1HMY: Crystal Structure of the Hhai DNA Methyltransferase Complexed With S- Adenosyl-l-methionine

The first three-dimensional structure of a DNA methyltransferase is presented. The crystal structure of the DNA (cytosine-5)-methyltransferase, M.HhaI (recognition sequence: GCGC), complexed with S-adenosyl-L-methionine has been determined and refined at 2.5 A resolution. The core of the structure is dominated by sequence motifs conserved among all DNA (cytosine-5)-methyltransferases, and these are responsible for cofactor binding and methyltransferase function.
PDB ID: 1HMYDownload
MMDB ID: 56354
PDB Deposition Date: 1993/8/5
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 1HMY: monomeric; determined by author
Molecular Components in 1HMY
Label Count Molecule
Protein (1 molecule)
Haeiii Methyltransferase
Molecule annotation
Chemical (1 molecule)
* Click molecule labels to explore molecular sequence information.

Citing MMDB