Insights Into Erbb Signaling From the Structure of the Erbb2- Pertuzumab Complex
MMDB ID: 27406PDB ID: 1S78help
PDB Deposition Date: 2004/1/29help
Updated in MMDB: 02/2013  help
Experimental Method:
X-Ray Diffraction help
Resolution: 3.25  Åhelp
Source Organism:
Mus musculus ▼help
Similar Structures: help
Citation: help
Franklin MC, Carey KD, Vajdos FF, Leahy DJ, De Vos AM, Sliwkowski MX
Cancer Cell (2004) 5 p.317
  • help
Biological Unit: trimeric; determined by author, and by software (PISA)help
schmatic for structure MMDB ID=27406 biounit 1
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Molecular graphic for MMDB ID 27406 biounit 1
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Data Set:
Molecules and interactionshelp
Label Count Molecule Interactions
Proteins and interactions (3 molecules)
Receptor Protein-tyrosine Kinase Erbb-2
Show annotation
  • N-Acetyl-D-Glucosamine
  • Pertuzumab FAB Heavy Chain
  • Pertuzumab FAB Light Chain
Pertuzumab FAB Light Chain
Show annotation
  • Pertuzumab FAB Heavy Chain
  • Receptor Protein-tyrosine Kinase Erbb-2
Pertuzumab FAB Heavy Chain
Show annotation
  • Pertuzumab FAB Light Chain
  • Receptor Protein-tyrosine Kinase Erbb-2
Chemicals and interactions (5 molecules)
 -Click for PubChem compound information. 5
  • N-Acetyl-D-Glucosamine
  • Receptor Protein-tyrosine Kinase Erbb-2
* Click molecule labels to explore molecular sequence information.

Citing MMDB
Madej T, Addess KJ, Fong JH, Geer LY, Geer RC, Lanczycki CJ, Liu C, Lu S, Marchler-Bauer A, Panchenko AR, Chen J, Thiessen PA, Wang Y, Zhang D, Bryant SH. "MMDB: 3D structures and macromolecular interactions." Nucleic Acids Res. 2012 Jan; 40(Database issue):D461-4
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