Crystal Structure of Kpt251 in Complex With Crm1-ran-ranbp1
MMDB ID: 102785PDB ID: 4GPThelp
PDB Deposition Date: 2012/8/21help
Updated in MMDB: 01/2013  help
Experimental Method:
X-Ray Diffraction help
Resolution: 2.22  Åhelp
Source Organism:
Homo sapienshelp
Similar Structures: help
Citation: help
Etchin J, Sun Q, Kentsis A, Farmer A, Zhang ZC, Sanda T, Mansour MR, Barcelo C, Mccauley D, Kauffman M, Shacham S, Christie AL, Kung AL, Rodig SJ, Chook YM, Look AT
Leukemia (2013) 27 p.66
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Biological Unit: trimeric; determined by author, and by software (PISA)help
Interactions?
schmatic for structure MMDB ID=102785 biounit 1
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Molecular graphic for MMDB ID 102785 biounit 1
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Data Set:
Notice
ProteinChemical
Molecules and interactionshelp
Label Count Molecule Interactions
Proteins and interactions (3 molecules)
1
Gtp-binding Nuclear Protein Ran
Show annotation
  • Chloride Ion
  • Ethylene Glycol
  • Exportin-1
  • Guanylyl Imidodiphosphate
  • Magnesium Ion
  • Ran-specific Gtpase-activating Protein 1
1
Ran-specific Gtpase-activating Protein 1
Show annotation
  • Exportin-1
  • Gtp-binding Nuclear Protein Ran
1
Exportin-1
Show annotation
  • Chloride Ion
  • Ethylene Glycol
  • Glycerin
  • Gtp-binding Nuclear Protein Ran
  • Kpt-251
  • Ran-specific Gtpase-activating Protein 1
Chemicals and interactions (13 molecules)
 -Click for PubChem compound information. 1
  • Gtp-binding Nuclear Protein Ran
  • Magnesium Ion
 -Click for PubChem compound information. 1
  • Gtp-binding Nuclear Protein Ran
  • Guanylyl Imidodiphosphate
 -Click for PubChem compound information. 2
  • Exportin-1
  • Glycerin
  • Gtp-binding Nuclear Protein Ran
 -Click for PubChem compound information. 5
  • Exportin-1
  • Gtp-binding Nuclear Protein Ran
 -Click for PubChem compound information. 1
  • Exportin-1
 -Click for PubChem compound information. 3
  • Ethylene Glycol
  • Exportin-1
* Click molecule labels to explore molecular sequence information.

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