£€0€ €0€ €0€ €E»¡€0€ €1HD8£€0€¢€0€ €Protein Data Bank¡€ €¡€0€ €Ù¡€¢€¢€¡€0€ €PDB¡€¡€1HD8£€¡€0€ €С€ ¢€ €€¡€0€ €0€ € €0€0€ €¡€0€ €Davies£€C.Davies€€C.0€ €¡€0€ €White£€ S.W.White€€S.W.0€ €¡€0€ €Nicholas£€ R.A.Nicholas€€R.A.¡€0€ €¡€0€ €С€ ¢€ €€«€1€€€0€ €1€ €hCrystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-A resolution.¡€0€ € €0€0€ €¡€0€ €Davies£€C.Davies€€C.0€ €¡€0€ €White£€ S.W.White€€S.W.0€ €¡€0€ €Nicholas£€ R.A.Nicholas€€R.A.¡€ €^School of Biological Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom.¢€ €0€ €1€€€J. Biol. Chem.¥€ J Biol Chem§€ 0021-9258 €#The Journal of biological chemistry¡€0€ €¡€0€ €Ñ¡€¢€¡€276¢€1£€616-623š€eng¬€­€1€0€ €¡€¡€0€ €С€ ¢€€€ ¥€0€ € ¡€¡€0€ €Ñ¡€¢€€€ ¥€0€ €ÿ¡€¡€0€ €С€ ¢€€€ ¥€£€1€ €§X>¢€10.1074/jbc.M004471200£€ M004471200¢€0€¡€¡€0€ €Ñ¡€¢€¢€0€¢€ €0€ €1€ €gCrystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-A resolution¡€0€ €¡€0€ €Ñ¡€¢€£€‚lPenicillin-binding protein 5 (PBP 5) of Escherichia coli functions as a d-alanine carboxypeptidase, cleaving the C-terminal d-alanine residue from cell wall peptides. Like all PBPs, PBP 5 forms a covalent acyl-enzyme complex with beta-lactam antibiotics; however, PBP 5 is distinguished by its high rate of deacylation of the acyl-enzyme complex (t(12) approximately 9 min). A Gly-105 --> Asp mutation in PBP 5 markedly impairs this beta-lactamase activity (deacylation), with only minor effects on acylation, and promotes accumulation of a covalent complex with peptide substrates. To gain further insight into the catalytic mechanism of PBP 5, we determined the three-dimensional structure of the G105D mutant form of soluble PBP 5 (termed sPBP 5') at 2.3 A resolution. The structure is composed of two domains, a penicillin binding domain with a striking similarity to Class A beta-lactamases (TEM-1-like) and a domain of unknown function. In addition, the penicillin-binding domain contains an active site loop spatially equivalent to the Omega loop of beta-lactamases. In beta-lactamases, the Omega loop contains two amino acids involved in catalyzing deacylation. This similarity may explain the high beta-lactamase activity of wild-type PBP 5. Because of the low rate of deacylation of the G105D mutant, visualization of peptide substrates bound to the active site may be possible.¬€§X>€€«€1€€€0€ €1€ €‘Relations between beta-lactamases and penicillin-binding proteins: beta-lactamase activity of penicillin-binding protein 5 from Escherichia coli.¡€0€ € €0€0€ €¡€0€ €Nicholas£€ R.A.Nicholas€€R.A.0€ €¡€0€ € Strominger£€J.L.Strominger€€J.L.¡€ €_Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Massachusetts.¢€ €0€ €1€€€Rev. Infect. Dis.¥€Rev Infect Dis§€ 0162-0886 €Reviews of infectious diseases¡€0€ €¡€0€ €Ä¡€¡€10¢€4£€733-738š€eng¬€­€1€0€ €¡€¡€0€ €Ä¡€¢€0€ € ¡€¡€0€ €Ä¡€¢€€€¥€0€ €ÿ¡€¡€0€ €Ä¡€¢€€€¥€£€1€ €.žD¢€0€¡€¡€0€ €Ä¡€ ¢€ ¢€0€¢€ €0€ €1€ €Relations between beta-lactamases and penicillin-binding proteins: beta-lactamase activity of penicillin-binding protein 5 from Escherichia coli¡€0€ €¡€0€ €Ä¡€£€‚The molecular mechanism of the hydrolysis of penicillin by penicillin-binding protein (PBP) 5 was investigated. Cysteine-115 had been previously implicated in the hydrolysis of the acyl-enzyme intermediate in PBP5. In studies with oligonucleotide-directed mutagenesis, the role of cysteine-115 in the mechanism of PBP5 was investigated by the mutation of this residue to either a serine or an alanine residue. Genetic truncation of the studied proteins at their carboxyl termini resulted in the production of a soluble form of these proteins (sPBPs). The purified sPBPs were assayed for both their beta-lactamase and their D-alanine carboxypeptidase activities. The results of these assays indicate that the cysteine residue does not directly participate in the enzymatic mechanism. In a further investigation of the catalytic mechanism of beta-lactam hydrolysis, a soluble, naturally occurring mutant was purified in large amounts and crystallized from concentrated polyethylene glycol solutions. This mutant of PBP5 (sPBP5') has a near-normal acylation rate with respect to [14C]penicillin, but shows a drastic increase in the half-life of the acyl-enzyme complex. The crystals of sPBP5' diffract to greater than 3 A resolution and are suitable for detailed crystallographic analysis.¬€.žD€€«€1€€€0€ €1€ €ˆAn amino acid substitution that blocks the deacylation step in the enzyme mechanism of penicillin-binding protein 5 of Escherichia coli.¡€0€ € €0€0€ €¡€0€ € Broome-Smith£€J.Broome-Smith€€J.0€ €¡€0€ €Spratt£€ B.G.Spratt€€B.G.¢€ €0€ €1€€€ FEBS Lett.¥€ FEBS Lett§€ 0014-5793 € FEBS letters¡€0€ €¡€0€ €À¡€¢€ ¡€165¢€2£€185-189š€eng¬€­€1€0€ €¡€¡€0€ €À¡€¢€ 0€ € ¡€¡€0€ €À¡€¢€ €€¥€0€ €ÿ¡€¡€0€ €À¡€¢€ €€¥€£€1€ €`lL£€0014-5793(84)80166-0¢€0€¡€¡€0€ €À¡€¢€¢€0€¢€ €0€ €1€ €‡An amino acid substitution that blocks the deacylation step in the enzyme mechanism of penicillin-binding protein 5 of Escherichia coli¡€0€ €¡€0€ €À¡€¢€ £€‚¢A mutant of Escherichia coli has been described that produces an altered form of penicillin-binding protein 5 which still binds penicillin but is unable to catalyse the release of the bound penicilloyl moiety. We show that the mutation is caused by a single nucleotide transition that results in a change from glycine at residue 105 of the wild-type sequence of penicillin-binding protein 5 to aspartate in the mutant.¬€`lL¢€0€ €0€ €gCrystal Structure Of A Deacylation-Defective Mutant Of Penicillin-Binding Protein 5 At 2.3 A Resolution¡€ Hydrolase¢€‚Mol_id: 1; Organism_scientific: Escherichia Coli; Organism_taxid: 562; Cellular_location: Periplasm; Gene: Daca; Expression_system: Escherichia Coli; Expression_system_taxid: 562; Expression_system_strain: Mc1061; Expression_system_plasmid: Pbr322; Expression_system_gene: Daca£€‚&Crystal Structure Of A Deacylation-Defective Mutant Of Penicillin-Binding Protein 5 At 2.3 A Resolution Peptidoglycan Synthesis, Penicillin-Binding Protein, Dd- Carboxypeptidase, Hydrolase Mol_id: 1; Molecule: Penicillin-Binding Protein 5; Chain: A; Ec: 3.4.16.4; Engineered: Yes; Mutation: Yes§€ÿ¡€0€0€ €¡€0€ €A£€SEQRESš€¥€0€¢€0€ €Escherichia coli£€1€0€ €taxon¡€ €2€€1€Enterococcus coli7"Bacterium coli" (Migula 1895) Lehmann and Neumann 1896Bacterium coli"Bacillus coli" Migula 1895 Bacillus coli'"Bacterium coli commune" Escherich 1885Bacterium coli commune;Escherichia coli (Migula 1895) Castellani and Chalmers 1919¥€0€ € €0€ € Escherichia¡€coli£€aBacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia€€ Š€BCT¢€«€È£€0€0€ €¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €¡€ 3 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 4 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 5 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 6 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €¡€ 7 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €¡€ 8 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ € ¡€ 9 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ € ¡€ 10 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ € ¡€ 11 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ € ¡€ 12 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ € ¡€ 13 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €¡€ 14 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 15 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 16 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €¡€ 17 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 18 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 19 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €¡€ 20 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€70€ €¡€ 21 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 22 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 23 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 24 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €¡€ 25 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€70€ €¡€ 26 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 27 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €¡€ 28 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 29 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €¡€ 30 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €¡€ 31 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ € ¡€ 32 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €!¡€ 33 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €"¡€ 34 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €#¡€ 35 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €$¡€ 36 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €%¡€ 37 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €&¡€ 38 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €'¡€ 39 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €(¡€ 40 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €)¡€ 41 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €*¡€ 42 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €+¡€ 43 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €,¡€ 44 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €-¡€ 45 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €.¡€ 46 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €/¡€ 47 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €0¡€ 48 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ €1¡€ 49 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ €2¡€ 50 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €3¡€ 51 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €4¡€ 52 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€70€ €5¡€ 53 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €6¡€ 54 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €7¡€ 55 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €8¡€ 56 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €9¡€ 57 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €:¡€ 58 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ €;¡€ 59 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €<¡€ 60 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €=¡€ 61 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €>¡€ 62 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €?¡€ 63 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €@¡€ 64 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €A¡€ 65 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €B¡€ 66 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €C¡€ 67 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €D¡€ 68 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €E¡€ 69 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €F¡€ 70 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €G¡€ 71 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €H¡€ 72 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €I¡€ 73 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €J¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €K¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €L¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€40€ €M¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €N¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €O¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €P¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Q¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €R¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €S¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €T¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €U¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €V¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €W¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €X¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Y¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ €Z¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €[¡€ 91 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €\¡€ 92 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €]¡€ 93 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €^¡€ 94 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €_¡€ 95 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ €`¡€ 96 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €a¡€ 97 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €b¡€ 98 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €c¡€ 99 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €d¡€ 100 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €e¡€ 101 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €f¡€ 102 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €g¡€ 103 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €h¡€ 104 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €i¡€ 105 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €j¡€ 106 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €k¡€ 107 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €l¡€ 108 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €m¡€ 109 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €n¡€ 110 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €o¡€ 111 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €p¡€ 112 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €q¡€ 113 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €r¡€ 114 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €s¡€ 115 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €t¡€ 116 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €u¡€ 117 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €v¡€ 118 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ €w¡€ 119 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €x¡€ 120 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €y¡€ 121 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €z¡€ 122 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €{¡€ 123 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €|¡€ 124 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €}¡€ 125 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €~¡€ 126 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 127 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €€¡€ 128 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 129 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €‚¡€ 130 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €ƒ¡€ 131 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €„¡€ 132 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €…¡€ 133 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ €†¡€ 134 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €‡¡€ 135 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €ˆ¡€ 136 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€70€ €‰¡€ 137 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €Š¡€ 138 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €‹¡€ 139 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Œ¡€ 140 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 141 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ž¡€ 142 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 143 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €¡€ 144 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €‘¡€ 145 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €’¡€ 146 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €“¡€ 147 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €”¡€ 148 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €•¡€ 149 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €–¡€ 150 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €—¡€ 151 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €˜¡€ 152 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €™¡€ 153 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €š¡€ 154 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €›¡€ 155 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €œ¡€ 156 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €¡€ 157 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €ž¡€ 158 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ÿ¡€ 159 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€70€ € ¡€ 160 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €¡¡€ 161 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €¢¡€ 162 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €£¡€ 163 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €€¡€ 164 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €¥¡€ 165 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ €Š¡€ 166 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €§¡€ 167 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €š¡€ 168 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €©¡€ 169 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €ª¡€ 170 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €«¡€ 171 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¬¡€ 172 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €­¡€ 173 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €®¡€ 174 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¯¡€ 175 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €°¡€ 176 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €±¡€ 177 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €²¡€ 178 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €³¡€ 179 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ž¡€ 180 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€70€ €µ¡€ 181 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €¶¡€ 182 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €·¡€ 183 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€70€ €ž¡€ 184 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €¹¡€ 185 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €º¡€ 186 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €»¡€ 187 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Œ¡€ 188 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €œ¡€ 189 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €Ÿ¡€ 190 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €¿¡€ 191 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €À¡€ 192 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Á¡€ 193 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 194 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €á€ 195 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ä¡€ 196 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Å¡€ 197 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Æ¡€ 198 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ç¡€ 199 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €È¡€ 200 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €É¡€ 201 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ê¡€ 202 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ë¡€ 203 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€40€ €Ì¡€ 204 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €Í¡€ 205 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ρ€ 206 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €Ï¡€ 207 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €С€ 208 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ñ¡€ 209 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €Ò¡€ 210 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €Ó¡€ 211 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ô¡€ 212 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Õ¡€ 213 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €Ö¡€ 214 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €ס€ 215 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ø¡€ 216 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ù¡€ 217 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €Ú¡€ 218 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €Û¡€ 219 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €Ü¡€ 220 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Ý¡€ 221 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Þ¡€ 222 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€70€ €ß¡€ 223 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €ࡀ 224 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €ᡀ 225 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €⡀ 226 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €㡀 227 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €䡀 228 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €塀 229 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €桀 230 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €础 231 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €血 232 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €顀 233 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ €ꡀ 234 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €례 235 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €졀 236 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €í¡€ 237 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ € 238 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ € 239 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €ð¡€ 240 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ €ñ¡€ 241 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €ò¡€ 242 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €ó¡€ 243 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €ô¡€ 244 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €õ¡€ 245 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €ö¡€ 246 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €÷¡€ 247 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €ø¡€ 248 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €ù¡€ 249 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €ú¡€ 250 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €û¡€ 251 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €ü¡€ 252 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €ý¡€ 253 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €þ¡€ 254 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €ÿ¡€ 255 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 256 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 257 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €¡€ 258 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€40€ €¡€ 259 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 260 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €¡€ 261 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 262 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €¡€ 263 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €¡€ 264 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ € ¡€ 265 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ € ¡€ 266 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ € ¡€ 267 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ € ¡€ 268 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ € ¡€ 269 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 270 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €¡€ 271 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €¡€ 272 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 273 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €¡€ 274 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 275 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €¡€ 276 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 277 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €¡€ 278 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 279 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €¡€ 280 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €¡€ 281 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€40€ €¡€ 282 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €¡€ 283 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 284 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €¡€ 285 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €¡€ 286 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €¡€ 287 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ € ¡€ 288 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €!¡€ 289 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €"¡€ 290 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €#¡€ 291 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €$¡€ 292 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €%¡€ 293 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €&¡€ 294 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €'¡€ 295 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €(¡€ 296 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €)¡€ 297 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€70€ €*¡€ 298 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €+¡€ 299 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €,¡€ 300 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €-¡€ 301 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €.¡€ 302 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €/¡€ 303 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €0¡€ 304 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €1¡€ 305 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€%0€ €2¡€ 306 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €3¡€ 307 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €4¡€ 308 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €5¡€ 309 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €6¡€ 310 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €7¡€ 311 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €8¡€ 312 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€70€ €9¡€ 313 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €:¡€ 314 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €;¡€ 315 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €<¡€ 316 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €=¡€ 317 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€.0€ €>¡€ 318 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €?¡€ 319 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €@¡€ 320 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €A¡€ 321 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €B¡€ 322 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €C¡€ 323 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €D¡€ 324 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €E¡€ 325 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €F¡€ 326 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €G¡€ 327 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €H¡€ 328 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €I¡€ 329 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €J¡€ 330 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €K¡€ 331 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €L¡€ 332 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €M¡€ 333 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €N¡€ 334 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €O¡€ 335 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €P¡€ 336 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Q¡€ 337 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €R¡€ 338 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €S¡€ 339 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ €T¡€ 340 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €U¡€ 341 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €V¡€ 342 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €W¡€ 343 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €X¡€ 344 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €Y¡€ 345 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €Z¡€ 346 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €[¡€ 347 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €\¡€ 348 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €]¡€ 349 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €^¡€ 350 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €_¡€ 351 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €`¡€ 352 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €a¡€ 353 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €b¡€ 354 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €c¡€ 355 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €d¡€ 356 ¢€ €0€ €e¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €f¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €g¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €h¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€+0€ €i¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€:0€ €j¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €k¡€ ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ €€0€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€ ¢€ 0€ €0€ €¡€ ¢€¡€0€ €¡€ ¢€0€ €0€ €¡€ ¢€¡€0€ €¡€ ¢€0€ €0€ €¡€ ¢€¡€0€ €¡€ ¢€ 0€ €0€ €¡€ ¢€¡€0€ €¡€ ¢€0€ €0€ €¡€ ¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€ ¢€0€ €0€ €¡€ ¢€¡€0€ €¡€!¢€ 0€ €0€ €¡€!¢€¡€0€ €¡€"¢€0€ €0€ €¡€"¢€¡€0€ €¡€#¢€0€ €0€ €¡€#¢€¡€0€ €¡€$¢€0€ €0€ €¡€$¢€¡€0€ €¡€%¢€ 0€ €0€ €¡€%¢€¡€0€ €¡€&¢€ 0€ €0€ €¡€&¢€¡€0€ €¡€'¢€ 0€ €0€ €¡€'¢€¡€0€ €¡€(¢€ 0€ €0€ €¡€(¢€¡€0€ €¡€)¢€ 0€ €0€ €¡€)¢€¡€0€ €¡€*¢€0€ €0€ €¡€*¢€¡€0€ €¡€+¢€0€ €0€ €¡€+¢€¡€0€ €¡€,¢€0€ €0€ €¡€,¢€¡€0€ €¡€-¢€ 0€ €0€ €¡€-¢€¡€0€ €¡€.¢€ 0€ €0€ €¡€.¢€¡€0€ €¡€/¢€ 0€ €0€ €¡€/¢€¡€0€ €¡€0¢€0€ €0€ €¡€0¢€¡€0€ €¡€1¢€0€ €0€ €¡€1¢€¡€0€ €¡€2¢€ 0€ €0€ €¡€2¢€¡€0€ €¡€3¢€0€ €0€ €¡€3¢€¡€0€ €¡€4¢€0€ €0€ €¡€4¢€¡€0€ €¡€5¢€ 0€ €0€ €¡€5¢€¡€0€ €¡€6¢€ 0€ €0€ €¡€6¢€¡€0€ €¡€7¢€0€ €0€ €¡€7¢€¡€0€ €¡€8¢€0€ €0€ €¡€8¢€¡€0€ €¡€9¢€0€ €0€ €¡€9¢€¡€0€ €¡€:¢€0€ €0€ €¡€:¢€¡€0€ €¡€;¢€ 0€ €0€ €¡€;¢€¡€0€ €¡€<¢€0€ €0€ €¡€<¢€¡€0€ €¡€=¢€0€ €0€ €¡€=¢€¡€0€ €¡€>¢€ 0€ €0€ €¡€>¢€¡€0€ €¡€?¢€0€ €0€ €¡€?¢€¡€0€ €¡€@¢€ 0€ €0€ €¡€@¢€¡€0€ €¡€A¢€ 0€ €0€ €¡€A¢€¡€0€ €¡€B¢€ 0€ €0€ €¡€B¢€¡€0€ €¡€C¢€ 0€ €0€ €¡€C¢€¡€0€ €¡€D¢€ 0€ €0€ €¡€D¢€¡€0€ €¡€E¢€ 0€ €0€ €¡€E¢€¡€0€ €¡€F¢€ 0€ €0€ €¡€F¢€¡€0€ €¡€G¢€ 0€ €0€ €¡€G¢€¡€0€ €¡€H¢€0€ €0€ €¡€H¢€¡€0€ €¡€I¢€0€ €0€ €¡€[¢€¡€0€ €¡€\¢€ 0€ €0€ €¡€\¢€¡€0€ €¡€]¢€0€ €0€ €¡€]¢€¡€0€ €¡€^¢€0€ €0€ €¡€^¢€¡€0€ €¡€_¢€0€ €0€ €¡€_¢€¡€0€ €¡€`¢€0€ €0€ €¡€`¢€¡€0€ €¡€a¢€ 0€ €0€ €¡€a¢€¡€0€ €¡€b¢€0€ €0€ €¡€b¢€¡€0€ €¡€c¢€ 0€ €0€ €¡€c¢€¡€0€ €¡€d¢€0€ €0€ €¡€d¢€¡€0€ €¡€e¢€0€ €0€ €¡€e¢€¡€0€ €¡€f¢€ 0€ €0€ €¡€f¢€¡€0€ €¡€g¢€ 0€ €0€ €¡€g¢€¡€0€ €¡€h¢€ 0€ €0€ €¡€h¢€¡€0€ €¡€i¢€ 0€ €0€ €¡€i¢€¡€0€ €¡€j¢€ 0€ €0€ €¡€j¢€¡€0€ €¡€k¢€0€ €0€ €¡€k¢€¡€0€ €¡€l¢€ 0€ €0€ €¡€l¢€¡€0€ €¡€m¢€0€ €0€ €¡€m¢€¡€0€ €¡€n¢€0€ €0€ €¡€n¢€¡€0€ €¡€o¢€0€ €0€ €¡€o¢€¡€0€ €¡€p¢€0€ €0€ €¡€p¢€¡€0€ €¡€q¢€ 0€ €0€ €¡€q¢€¡€0€ €¡€r¢€0€ €0€ €¡€r¢€¡€0€ €¡€s¢€0€ €0€ €¡€s¢€¡€0€ €¡€t¢€ 0€ €0€ €¡€t¢€¡€0€ €¡€u¢€0€ €0€ €¡€u¢€¡€0€ €¡€v¢€0€ €0€ €¡€v¢€¡€0€ €¡€w¢€0€ €0€ €¡€w¢€¡€0€ €¡€x¢€ 0€ €0€ €¡€x¢€¡€0€ €¡€y¢€0€ €0€ €¡€y¢€¡€0€ €¡€z¢€0€ €0€ €¡€z¢€¡€0€ €¡€{¢€0€ €0€ €¡€{¢€¡€0€ €¡€|¢€0€ €0€ €¡€|¢€¡€0€ €¡€}¢€0€ €0€ €¡€}¢€¡€0€ €¡€~¢€0€ €0€ €¡€~¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€€¢€0€ €0€ €¡€€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€‚¢€ 0€ €0€ €¡€‚¢€¡€0€ €¡€ƒ¢€0€ €0€ €¡€ƒ¢€¡€0€ €¡€„¢€ 0€ €0€ €¡€„¢€¡€0€ €¡€…¢€0€ €0€ €¡€…¢€¡€0€ €¡€†¢€0€ €0€ €¡€†¢€¡€0€ €¡€‡¢€0€ €0€ €¡€‡¢€¡€0€ €¡€ˆ¢€0€ €0€ €¡€ˆ¢€¡€0€ €¡€‰¢€ 0€ €0€ €¡€‰¢€¡€0€ €¡€Š¢€0€ €0€ €¡€Š¢€¡€0€ €¡€‹¢€0€ €0€ €¡€‹¢€¡€0€ €¡€Œ¢€ 0€ €0€ €¡€Œ¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€Ž¢€ 0€ €0€ €¡€Ž¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€‘¢€ 0€ €0€ €¡€‘¢€¡€0€ €¡€’¢€ 0€ €0€ €¡€’¢€¡€0€ €¡€“¢€0€ €0€ €¡€“¢€¡€0€ €¡€”¢€0€ €0€ €¡€”¢€¡€0€ €¡€•¢€ 0€ €0€ €¡€•¢€¡€0€ €¡€–¢€ 0€ €0€ €¡€–¢€¡€0€ €¡€—¢€ 0€ €0€ €¡€—¢€¡€0€ €¡€˜¢€0€ €0€ €¡€˜¢€¡€0€ €¡€™¢€ 0€ €0€ €¡€™¢€¡€0€ €¡€š¢€ 0€ €0€ €¡€š¢€¡€0€ €¡€›¢€0€ €0€ €¡€›¢€¡€0€ €¡€œ¢€ 0€ €0€ €¡€œ¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€ž¢€0€ €0€ €¡€ž¢€¡€0€ €¡€Ÿ¢€0€ €0€ €¡€Ÿ¢€¡€0€ €¡€ ¢€0€ €0€ €¡€ ¢€¡€0€ €¡€¡¢€0€ €0€ €¡€¡¢€¡€0€ €¡€¢¢€0€ €0€ €¡€¢¢€¡€0€ €¡€£¢€ 0€ €0€ €¡€£¢€¡€0€ €¡€€¢€ 0€ €0€ €¡€€¢€¡€0€ €¡€¥¢€0€ €0€ €¡€¥¢€¡€0€ €¡€Š¢€0€ €0€ €¡€Š¢€¡€0€ €¡€§¢€ 0€ €0€ €¡€§¢€¡€0€ €¡€š¢€ 0€ €0€ €¡€š¢€¡€0€ €¡€©¢€0€ €0€ €¡€©¢€¡€0€ €¡€ª¢€0€ €0€ €¡€ª¢€¡€0€ €¡€«¢€0€ €0€ €¡€«¢€¡€0€ €¡€¬¢€ 0€ €0€ €¡€¬¢€¡€0€ €¡€­¢€ 0€ €0€ €¡€­¢€¡€0€ €¡€®¢€ 0€ €0€ €¡€®¢€¡€0€ €¡€¯¢€ 0€ €0€ €¡€¯¢€¡€0€ €¡€°¢€ 0€ €0€ €¡€°¢€¡€0€ €¡€±¢€0€ €0€ €¡€±¢€¡€0€ €¡€²¢€0€ €0€ €¡€²¢€¡€0€ €¡€³¢€ 0€ €0€ €¡€³¢€¡€0€ €¡€Ž¢€0€ €0€ €¡€Ž¢€¡€0€ €¡€µ¢€0€ €0€ €¡€µ¢€¡€0€ €¡€¶¢€ 0€ €0€ €¡€¶¢€¡€0€ €¡€·¢€0€ €0€ €¡€·¢€¡€0€ €¡€ž¢€ 0€ €0€ €¡€ž¢€¡€0€ €¡€¹¢€ 0€ €0€ €¡€¹¢€¡€0€ €¡€º¢€ 0€ €0€ €¡€º¢€¡€0€ €¡€»¢€ 0€ €0€ €¡€»¢€¡€0€ €¡€Œ¢€0€ €0€ €¡€Œ¢€¡€0€ €¡€œ¢€ 0€ €0€ €¡€œ¢€¡€0€ €¡€Ÿ¢€0€ €0€ €¡€Ÿ¢€¡€0€ €¡€¿¢€0€ €0€ €¡€¿¢€¡€0€ €¡€À¢€0€ €0€ €¡€À¢€¡€0€ €¡€Á¢€ 0€ €0€ €¡€Á¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€â€0€ €0€ €¡€â€¡€0€ €¡€Ä¢€ 0€ €0€ €¡€Ä¢€¡€0€ €¡€Å¢€0€ €0€ €¡€Å¢€¡€0€ €¡€Æ¢€ 0€ €0€ €¡€Æ¢€¡€0€ €¡€Ç¢€0€ €0€ €¡€Ç¢€¡€0€ €¡€È¢€0€ €0€ €¡€È¢€¡€0€ €¡€É¢€ 0€ €0€ €¡€É¢€¡€0€ €¡€Ê¢€ 0€ €0€ €¡€Ê¢€¡€0€ €¡€Ë¢€0€ €0€ €¡€Ë¢€¡€0€ €¡€Ì¢€ 0€ €0€ €¡€Ì¢€¡€0€ €¡€Í¢€0€ €0€ €¡€Í¢€¡€0€ €¡€΢€0€ €0€ €¡€΢€¡€0€ €¡€Ï¢€ 0€ €0€ €¡€Ï¢€¡€0€ €¡€Т€0€ €0€ €¡€Т€¡€0€ €¡€Ñ¢€ 0€ €0€ €¡€Ñ¢€¡€0€ €¡€Ò¢€ 0€ €0€ €¡€Ò¢€¡€0€ €¡€Ó¢€0€ €0€ €¡€Ó¢€¡€0€ €¡€Ô¢€ 0€ €0€ €¡€Ô¢€¡€0€ €¡€Õ¢€ 0€ €0€ €¡€Õ¢€¡€0€ €¡€Ö¢€ 0€ €0€ €¡€Ö¢€¡€0€ €¡€×¢€0€ €0€ €¡€×¢€¡€0€ €¡€Ø¢€ 0€ €0€ €¡€Ø¢€¡€0€ €¡€Ù¢€ 0€ €0€ €¡€Ù¢€¡€0€ €¡€Ú¢€ 0€ €0€ €¡€Ú¢€¡€0€ €¡€Û¢€ 0€ €0€ €¡€Û¢€¡€0€ €¡€Ü¢€0€ €0€ €¡€Ü¢€¡€0€ €¡€Ý¢€0€ €0€ €¡€Ý¢€¡€0€ €¡€Þ¢€0€ €0€ €¡€Þ¢€¡€0€ €¡€ߢ€0€ €0€ €¡€ߢ€¡€0€ €¡€ࢀ 0€ €0€ €¡€ࢀ¡€0€ €¡€ᢀ 0€ €0€ €¡€ᢀ¡€0€ €¡€⢀0€ €0€ €¡€⢀¡€0€ €¡€㢀0€ €0€ €¡€㢀¡€0€ €¡€䢀0€ €0€ €¡€䢀¡€0€ €¡€墀 0€ €0€ €¡€墀¡€0€ €¡€梀 0€ €0€ €¡€梀¡€0€ €¡€碀0€ €0€ €¡€碀¡€0€ €¡€袀0€ €0€ €¡€袀¡€0€ €¡€颀0€ €0€ €¡€颀¡€0€ €¡€ꢀ 0€ €0€ €¡€ꢀ¡€0€ €¡€뢀 0€ €0€ €¡€뢀¡€0€ €¡€좀 0€ €0€ €¡€좀¡€0€ €¡€í¢€0€ €0€ €¡€í¢€¡€0€ €¡€0€ €0€ €¡€¡€0€ €¡€ 0€ €0€ €¡€¡€0€ €¡€ð¢€0€ €0€ €¡€ð¢€¡€0€ €¡€ñ¢€0€ €0€ €¡€ñ¢€¡€0€ €¡€ò¢€0€ €0€ €¡€ò¢€¡€0€ €¡€ó¢€ 0€ €0€ €¡€ó¢€¡€0€ €¡€ô¢€ 0€ €0€ €¡€ô¢€¡€0€ €¡€õ¢€0€ €0€ €¡€õ¢€¡€0€ €¡€ö¢€ 0€ €0€ €¡€ö¢€¡€0€ €¡€÷¢€0€ €0€ €¡€÷¢€¡€0€ €¡€ø¢€ 0€ €0€ €¡€ø¢€¡€0€ €¡€ù¢€ 0€ €0€ €¡€ù¢€¡€0€ €¡€ú¢€0€ €0€ €¡€ú¢€¡€0€ €¡€û¢€ 0€ €0€ €¡€û¢€¡€0€ €¡€ü¢€0€ €0€ €¡€ü¢€¡€0€ €¡€ý¢€ 0€ €0€ €¡€ý¢€¡€0€ €¡€þ¢€ 0€ €0€ €¡€þ¢€¡€0€ €¡€ÿ¢€ 0€ €0€ €¡€ÿ¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€ ¢€ 0€ €0€ €¡€ ¢€¡€0€ €¡€ ¢€ 0€ €0€ €¡€ ¢€¡€0€ €¡€ ¢€0€ €0€ €¡€ ¢€¡€0€ €¡€ ¢€0€ €0€ €¡€ ¢€¡€0€ €¡€ ¢€ 0€ €0€ €¡€ ¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€¢€ 0€ €0€ €¡€¢€¡€0€ €¡€ ¢€0€ €0€ €¡€ ¢€¡€0€ €¡€!¢€0€ €0€ €¡€!¢€¡€0€ €¡€"¢€ 0€ €0€ €¡€"¢€¡€0€ €¡€#¢€0€ €0€ €¡€#¢€¡€0€ €¡€$¢€ 0€ €0€ €¡€$¢€¡€0€ €¡€%¢€ 0€ €0€ €¡€%¢€¡€0€ €¡€&¢€ 0€ €0€ €¡€&¢€¡€0€ €¡€'¢€ 0€ €0€ €¡€'¢€¡€0€ €¡€(¢€ 0€ €0€ €¡€(¢€¡€0€ €¡€)¢€0€ €0€ €¡€)¢€¡€0€ €¡€*¢€ 0€ €0€ €¡€*¢€¡€0€ €¡€+¢€ 0€ €0€ €¡€+¢€¡€0€ €¡€,¢€ 0€ €0€ €¡€,¢€¡€0€ €¡€-¢€0€ €0€ €¡€-¢€¡€0€ €¡€.¢€ 0€ €0€ €¡€.¢€¡€0€ €¡€/¢€0€ €0€ €¡€/¢€¡€0€ €¡€0¢€ 0€ €0€ €¡€0¢€¡€0€ €¡€1¢€0€ €0€ €¡€1¢€¡€0€ €¡€2¢€ 0€ €0€ €¡€2¢€¡€0€ €¡€3¢€ 0€ €0€ €¡€3¢€¡€0€ €¡€4¢€ 0€ €0€ €¡€4¢€¡€0€ €¡€5¢€ 0€ €0€ €¡€5¢€¡€0€ €¡€6¢€0€ €0€ €¡€6¢€¡€0€ €¡€7¢€0€ €0€ €¡€7¢€¡€0€ €¡€8¢€0€ €0€ €¡€8¢€¡€0€ €¡€9¢€ 0€ €0€ €¡€9¢€¡€0€ €¡€:¢€ 0€ €0€ €¡€:¢€¡€0€ €¡€;¢€0€ €0€ €¡€;¢€¡€0€ €¡€<¢€0€ €0€ €¡€<¢€¡€0€ €¡€=¢€0€ €0€ €¡€=¢€¡€0€ €¡€>¢€ 0€ €0€ €¡€>¢€¡€0€ €¡€?¢€ 0€ €0€ €¡€?¢€¡€0€ €¡€@¢€ 0€ €0€ €¡€@¢€¡€0€ €¡€A¢€0€ €0€ €¡€A¢€¡€0€ €¡€B¢€0€ €0€ €¡€B¢€¡€0€ €¡€C¢€ 0€ €0€ €¡€C¢€¡€0€ €¡€D¢€0€ €0€ €¡€D¢€¡€0€ €¡€E¢€ 0€ €0€ €¡€E¢€¡€0€ €¡€F¢€0€ €0€ €¡€F¢€¡€0€ €¡€G¢€0€ €0€ €¡€G¢€¡€0€ €¡€H¢€ 0€ €0€ €¡€H¢€¡€0€ €¡€I¢€ 0€ €0€ €¡€I¢€¡€0€ €¡€J¢€0€ €0€ €¡€J¢€¡€0€ €¡€K¢€ 0€ €0€ €¡€K¢€¡€0€ €¡€L¢€ 0€ €0€ €¡€L¢€¡€0€ €¡€M¢€0€ €0€ €¡€M¢€¡€0€ €¡€N¢€0€ €0€ €¡€N¢€¡€0€ €¡€O¢€0€ €0€ €¡€O¢€¡€0€ €¡€P¢€ 0€ €0€ €¡€P¢€¡€0€ €¡€Q¢€ 0€ €0€ €¡€Q¢€¡€0€ €¡€R¢€0€ €0€ €¡€R¢€¡€0€ €¡€S¢€ 0€ €0€ €¡€S¢€¡€0€ €¡€T¢€ 0€ €0€ €¡€T¢€¡€0€ €¡€U¢€ 0€ €0€ €¡€U¢€¡€0€ €¡€V¢€ 0€ €0€ €¡€V¢€¡€0€ €¡€W¢€0€ €0€ €¡€W¢€¡€0€ €¡€X¢€ 0€ €0€ €¡€X¢€¡€0€ €¡€Y¢€0€ €0€ €¡€Y¢€¡€0€ €¡€Z¢€ 0€ €0€ €¡€Z¢€¡€0€ €¡€[¢€ 0€ €0€ €¡€[¢€¡€0€ €¡€\¢€ 0€ €0€ €¡€\¢€¡€0€ €¡€]¢€ 0€ €0€ €¡€]¢€¡€0€ €¡€^¢€0€ €0€ €¡€^¢€¡€0€ €¡€_¢€ 0€ €0€ €¡€_¢€¡€0€ €¡€`¢€ 0€ €0€ €¡€`¢€¡€0€ €¡€a¢€0€ €0€ €¡€a¢€¡€0€ €¡€b¢€ 0€ €0€ €¡€b¢€¡€0€ €¡€c¢€0€ €0€ €¡€c¢€¡€0€ €¡€d¢€0€ €¡€0€ €1š€£€0€0€ €¡€ 1 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 2 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 3 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 4 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 5 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 6 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 7 ¢€ €0€ € ¡€0€ €1š€£€0€0€ €¡€ 8 ¢€ €0€ € ¡€0€ €1š€£€0€0€ €¡€ 9 ¢€ €0€ € ¡€0€ €1š€£€0€0€ €¡€ 10 ¢€ €0€ € ¡€0€ €1š€£€0€0€ €¡€ 11 ¢€ €0€ € ¡€0€ €1š€£€0€0€ €¡€ 12 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 13 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 14 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 15 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 16 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 17 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 18 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 19 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 20 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 21 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 22 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 23 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 24 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 25 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 26 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 27 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 28 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 29 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 30 ¢€ €0€ € ¡€0€ €1š€£€0€0€ €¡€ 31 ¢€ €0€ €!¡€0€ €1š€£€0€0€ €¡€ 32 ¢€ €0€ €"¡€0€ €1š€£€0€0€ €¡€ 33 ¢€ €0€ €#¡€0€ €1š€£€0€0€ €¡€ 34 ¢€ €0€ €$¡€0€ €1š€£€0€0€ €¡€ 35 ¢€ €0€ €%¡€0€ €1š€£€0€0€ €¡€ 36 ¢€ €0€ €&¡€0€ €1š€£€0€0€ €¡€ 37 ¢€ €0€ €'¡€0€ €1š€£€0€0€ €¡€ 38 ¢€ €0€ €(¡€0€ €1š€£€0€0€ €¡€ 39 ¢€ €0€ €)¡€0€ €1š€£€0€0€ €¡€ 40 ¢€ €0€ €*¡€0€ €1š€£€0€0€ €¡€ 41 ¢€ €0€ €+¡€0€ €1š€£€0€0€ €¡€ 42 ¢€ €0€ €,¡€0€ €1š€£€0€0€ €¡€ 43 ¢€ €0€ €-¡€0€ €1š€£€0€0€ €¡€ 44 ¢€ €0€ €.¡€0€ €1š€£€0€0€ €¡€ 45 ¢€ €0€ €/¡€0€ €1š€£€0€0€ €¡€ 46 ¢€ €0€ €0¡€0€ €1š€£€0€0€ €¡€ 47 ¢€ €0€ €1¡€0€ €1š€£€0€0€ €¡€ 48 ¢€ €0€ €2¡€0€ €1š€£€0€0€ €¡€ 49 ¢€ €0€ €3¡€0€ €1š€£€0€0€ €¡€ 50 ¢€ €0€ €4¡€0€ €1š€£€0€0€ €¡€ 51 ¢€ €0€ €5¡€0€ €1š€£€0€0€ €¡€ 52 ¢€ €0€ €6¡€0€ €1š€£€0€0€ €¡€ 53 ¢€ €0€ €7¡€0€ €1š€£€0€0€ €¡€ 54 ¢€ €0€ €8¡€0€ €1š€£€0€0€ €¡€ 55 ¢€ €0€ €9¡€0€ €1š€£€0€0€ €¡€ 56 ¢€ €0€ €:¡€0€ €1š€£€0€0€ €¡€ 57 ¢€ €0€ €;¡€0€ €1š€£€0€0€ €¡€ 58 ¢€ €0€ €<¡€0€ €1š€£€0€0€ €¡€ 59 ¢€ €0€ €=¡€0€ €1š€£€0€0€ €¡€ 60 ¢€ €0€ €>¡€0€ €1š€£€0€0€ €¡€ 61 ¢€ €0€ €?¡€0€ €1š€£€0€0€ €¡€ 62 ¢€ €0€ €@¡€0€ €1š€£€0€0€ €¡€ 63 ¢€ €0€ €A¡€0€ €1š€£€0€0€ €¡€ 64 ¢€ €0€ €B¡€0€ €1š€£€0€0€ €¡€ 65 ¢€ €0€ €C¡€0€ €1š€£€0€0€ €¡€ 66 ¢€ €0€ €D¡€0€ €1š€£€0€0€ €¡€ 67 ¢€ €0€ €E¡€0€ €1š€£€0€0€ €¡€ 68 ¢€ €0€ €F¡€0€ €1š€£€0€0€ €¡€ 69 ¢€ €0€ €G¡€0€ €1š€£€0€0€ €¡€ 70 ¢€ €0€ €H¡€0€ €1š€£€0€0€ €¡€ 71 ¢€ €0€ €I¡€0€ €1š€£€0€0€ €¡€ 72 ¢€ €0€ €J¡€0€ €1š€£€0€0€ €¡€ 73 ¢€ €0€ €K¡€0€ €1š€£€0€0€ €¡€ 74 ¢€ €0€ €L¡€0€ €1š€£€0€0€ €¡€ 75 ¢€ €0€ €M¡€0€ €1š€£€0€0€ €¡€ 76 ¢€ €0€ €N¡€0€ €1š€£€0€0€ €¡€ 77 ¢€ €0€ €O¡€0€ €1š€£€0€0€ €¡€ 78 ¢€ €0€ €P¡€0€ €1š€£€0€0€ €¡€ 79 ¢€ €0€ €Q¡€0€ €1š€£€0€0€ €¡€ 80 ¢€ €0€ €R¡€0€ €1š€£€0€0€ €¡€ 81 ¢€ €0€ €S¡€0€ €1š€£€0€0€ €¡€ 82 ¢€ €0€ €T¡€0€ €1š€£€0€0€ €¡€ 83 ¢€ €0€ €U¡€0€ €1š€£€0€0€ €¡€ 84 ¢€ €0€ €V¡€0€ €1š€£€0€0€ €¡€ 85 ¢€ €0€ €W¡€0€ €1š€£€0€0€ €¡€ 86 ¢€ €0€ €X¡€0€ €1š€£€0€0€ €¡€ 87 ¢€ €0€ €Y¡€0€ €1š€£€0€0€ €¡€ 88 ¢€ €0€ €Z¡€0€ €1š€£€0€0€ €¡€ 89 ¢€ €0€ €[¡€0€ €1š€£€0€0€ €¡€ 90 ¢€ €0€ €\¡€0€ €1š€£€0€0€ €¡€ 91 ¢€ €0€ €]¡€0€ €1š€£€0€0€ €¡€ 92 ¢€ €0€ €^¡€0€ €1š€£€0€0€ €¡€ 93 ¢€ €0€ €_¡€0€ €1š€£€0€0€ €¡€ 94 ¢€ €0€ €`¡€0€ €1š€£€0€0€ €¡€ 95 ¢€ €0€ €a¡€0€ €1š€£€0€0€ €¡€ 96 ¢€ €0€ €b¡€0€ €1š€£€0€0€ €¡€ 97 ¢€ €0€ €c¡€0€ €1š€£€0€0€ €¡€ 98 ¢€ €0€ €d¡€0€ €1š€£€0€0€ €¡€ 99 ¢€ €0€ €e¡€0€ €1š€£€0€0€ €¡€ 100 ¢€ €0€ €f¡€0€ €1š€£€0€0€ €¡€ 101 ¢€ €0€ €g¡€0€ €1š€£€0€0€ €¡€ 102 ¢€ €0€ €h¡€0€ €1š€£€0€0€ €¡€ 103 ¢€ €0€ €i¡€0€ €1š€£€0€0€ €¡€ 104 ¢€ €0€ €j¡€0€ €1š€£€0€0€ €¡€ 105 ¢€ €0€ €k¡€0€ €1š€£€0€0€ €¡€ 106 ¢€ €0€ €l¡€0€ €1š€£€0€0€ €¡€ 107 ¢€ €0€ €m¡€0€ €1š€£€0€0€ €¡€ 108 ¢€ €0€ €n¡€0€ €1š€£€0€0€ €¡€ 109 ¢€ €0€ €o¡€0€ €1š€£€0€0€ €¡€ 110 ¢€ €0€ €p¡€0€ €1š€£€0€0€ €¡€ 111 ¢€ €0€ €q¡€0€ €1š€£€0€0€ €¡€ 112 ¢€ €0€ €r¡€0€ €1š€£€0€0€ €¡€ 113 ¢€ €0€ €s¡€0€ €1š€£€0€0€ €¡€ 114 ¢€ €0€ €t¡€0€ €1š€£€0€0€ €¡€ 115 ¢€ €0€ €u¡€0€ €1š€£€0€0€ €¡€ 116 ¢€ €0€ €v¡€0€ €1š€£€0€0€ €¡€ 117 ¢€ €0€ €w¡€0€ €1š€£€0€0€ €¡€ 118 ¢€ €0€ €x¡€0€ €1š€£€0€0€ €¡€ 119 ¢€ €0€ €y¡€0€ €1š€£€0€0€ €¡€ 120 ¢€ €0€ €z¡€0€ €1š€£€0€0€ €¡€ 121 ¢€ €0€ €{¡€0€ €1š€£€0€0€ €¡€ 122 ¢€ €0€ €|¡€0€ €1š€£€0€0€ €¡€ 123 ¢€ €0€ €}¡€0€ €1š€£€0€0€ €¡€ 124 ¢€ €0€ €~¡€0€ €1š€£€0€0€ €¡€ 125 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 126 ¢€ €0€ €€¡€0€ €1š€£€0€0€ €¡€ 127 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 128 ¢€ €0€ €‚¡€0€ €1š€£€0€0€ €¡€ 129 ¢€ €0€ €ƒ¡€0€ €1š€£€0€0€ €¡€ 130 ¢€ €0€ €„¡€0€ €1š€£€0€0€ €¡€ 131 ¢€ €0€ €…¡€0€ €1š€£€0€0€ €¡€ 132 ¢€ €0€ €†¡€0€ €1š€£€0€0€ €¡€ 133 ¢€ €0€ €‡¡€0€ €1š€£€0€0€ €¡€ 134 ¢€ €0€ €ˆ¡€0€ €1š€£€0€0€ €¡€ 135 ¢€ €0€ €‰¡€0€ €1š€£€0€0€ €¡€ 136 ¢€ €0€ €Š¡€0€ €1š€£€0€0€ €¡€ 137 ¢€ €0€ €‹¡€0€ €1š€£€0€0€ €¡€ 138 ¢€ €0€ €Œ¡€0€ €1š€£€0€0€ €¡€ 139 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 140 ¢€ €0€ €Ž¡€0€ €1š€£€0€0€ €¡€ 141 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 142 ¢€ €0€ €¡€0€ €1š€£€0€0€ €¡€ 143 ¢€ €0€ €‘¡€0€ €1š€£€0€0€ €¡€ 144 ¢€ €0€ €’¡€0€ €1š€£€0€0€ €¡€ 145 ¢€ €£€0€0€ €¡€0€ €ASN£€¢€£€0€N€€0€0€ €¡€ N ¢€0€ N £€ 0€ €¡€ CA ¢€0€ CA £€ 0€ €¡€ C ¢€0€ C £€ 0€ €¡€ O ¢€0€ O £€ 0€ €¡€ CB ¢€0€ CB £€ 0€ €¡€ CG ¢€0€ CG £€ 0€ €¡€ OD1¢€0€ OD1£€ 0€ €¡€ ND2¢€0€ ND2£€ 0€ € ¡€ OXT¢€0€ OXT£€ ¥€0€0€ €¡€¢€ÿ0€ €¡€¢€ÿ0€ €¡€¢€ÿ0€ €¡€¢€ÿ0€ €¡€ ¢€ÿ0€ €¡€¢€ÿ0€ €¡€¢€ÿ0€ €¡€¢€ÿ0€ €¡€0€ €HOH£€¢€ÿ£€0€X€€0€0€ €¡€ O ¢€0€ O £€ ¥€0€£€0€0€ €¡€0€ €PDB secondary structure¢€0€0€ €¡€ 1¢€€€ €¡€¡€0€0€ €¡€*¢€-0€ €¡€ 2¢€€€ €¡€¡€0€0€ €¡€.¢€<0€ €¡€ 3¢€€€ €¡€¡€0€0€ €¡€c¢€n0€ €¡€ 4¢€€€ €¡€¡€0€0€ €¡€o¢€|0€ €¡€ 5¢€€€ €¡€¡€0€0€ €¡€}¢€0€ €¡€ 6¢€€€ €¡€¡€0€0€ €¡€¡¢€°0€ €¡€ 7¢€€€ €¡€¡€0€0€ €¡€°¢€µ0€ €¡€ 8¢€€€ €¡€¡€0€0€ €¡€¶¢€¹0€ € ¡€ 9¢€€€ €¡€¡€0€0€ €¡€Ç¢€Ì0€ € ¡€ 10¢€€€ €¡€¡€0€0€ €¡€ö¢€0€ € ¡€ 11¢€€€ €¡€¡€0€0€ €¡€0¢€40€ € ¡€ AA 1¢€€€ €¡€¡€0€0€ €¡€¢€"0€ € ¡€ AA 2¢€€€ €¡€¡€0€0€ €¡€¢€0€ €¡€ AA 3¢€€€ €¡€¡€0€0€ €¡€颀ò0€ €¡€ AA 4¢€€€ €¡€¡€0€0€ €¡€Ý¢€æ0€ €¡€ AA 5¢€€€ €¡€¡€0€0€ €¡€Ñ¢€Ù0€ €¡€ AB 1¢€€€ €¡€¡€0€0€ €¡€D¢€F0€ €¡€ AB 2¢€€€ €¡€¡€0€0€ €¡€`¢€b0€ €¡€ AC 1¢€€€ €¡€¡€0€0€ €¡€»¢€Ÿ0€ €¡€ AC 2¢€€€ €¡€¡€0€0€ €¡€Á¢€Ä0€ €¡€ AD 1¢€€€ €¡€¡€0€0€ €¡€¢€ 0€ €¡€ AD 2¢€€€ €¡€¡€0€0€ €¡€(¢€-0€ €¡€ AE 1¢€€€ €¡€¡€0€0€ €¡€5¢€:0€ €¡€ AE 2¢€€€ €¡€¡€0€0€ €¡€H¢€P0€ €¡€ AE 3¢€€€ €¡€¡€0€0€ €¡€S¢€\0€ €¡€ AE 4¢€€€ €¡€¡€0€0€ €¡€¢€#0€ €¡€ AE 5¢€€€ €¡€¡€0€0€ €¡€¢€0€ €¡€ AE 6¢€€€ €¡€¡€0€0€ €¡€?¢€@0€ €¡€0€ €!NCBI assigned secondary structure¢€0€0€ €¡€helix 1¢€€€ €¡€¡€0€0€ €¡€0¢€<0€ €¡€helix 2¢€€€ €¡€¡€0€0€ €¡€d¢€k0€ €¡€helix 3¢€€€ €¡€¡€0€0€ €¡€p¢€z0€ €¡€helix 4¢€€€ €¡€¡€0€0€ €¡€~¢€Œ0€ €¡€helix 5¢€€€ €¡€¡€0€0€ €¡€£¢€®0€ €¡€helix 6¢€€€ €¡€¡€0€0€ €¡€ú¢€0€ €¡€strand 1¢€€€ €¡€¡€0€0€ €¡€¢€0€ €¡€strand 2¢€€€ €¡€¡€0€0€ €¡€¢€#0€ € ¡€strand 3¢€€€ €¡€¡€0€0€ €¡€$¢€(0€ € ¡€strand 4¢€€€ €¡€¡€0€0€ €¡€C¢€G0€ € ¡€strand 5¢€€€ €¡€¡€0€0€ €¡€_¢€c0€ € ¡€strand 6¢€€€ €¡€¡€0€0€ €¡€¢€“0€ € ¡€strand 7¢€€€ €¡€¡€0€0€ €¡€ž¢€¢0€ €¡€strand 8¢€€€ €¡€¡€0€0€ €¡€º¢€¿0€ €¡€strand 9¢€€€ €¡€¡€0€0€ €¡€À¢€Å0€ €¡€ strand 10¢€€€ €¡€¡€0€0€ €¡€Т€Ù0€ €¡€ strand 11¢€€€ €¡€¡€0€0€ €¡€Ý¢€ç0€ €¡€ strand 12¢€€€ €¡€¡€0€0€ €¡€袀ó0€ €¡€ strand 13¢€€€ €¡€¡€0€0€ €¡€¢€ 0€ €¡€ strand 14¢€€€ €¡€¡€0€0€ €¡€¢€0€ €¡€ strand 15¢€€€ €¡€¡€0€0€ €¡€¢€#0€ €¡€ strand 16¢€€€ €¡€¡€0€0€ €¡€(¢€-0€ €¡€ strand 17¢€€€ €¡€¡€0€0€ €¡€4¢€;0€ €¡€ strand 18¢€€€ €¡€¡€0€0€ €¡€B¢€F0€ €¡€ strand 19¢€€€ €¡€¡€0€0€ €¡€G¢€Q0€ €¡€ strand 20¢€€€ €¡€¡€0€0€ €¡€R¢€V0€ €¡€ strand 21¢€€€ €¡€¡€0€0€ €¡€W¢€\0€ €¡€ strand 22¢€€€ €¡€¡€0€0€ €¡€]¢€a0€ €¡€0€ € NCBI Domains¢€0€0€ €¡€Domain¢€d€€ €¡€¡€0€0€ €¡€¢€#0€ €¡€Ë¢€0€ €¡€Domain¢€d€€ €¡€¡€0€0€ €¡€$¢€?0€ €¡€}¢€Ž0€ €¡€Domain¢€d€€ €¡€¡€0€0€ €¡€@¢€|0€ €¡€µ¢€Ê0€ €¡€Domain¢€d€€ €¡€¡€0€0€ €¡€¢€k€€0€0€ €¡€¢€0€ €QSingle-coordinate-per-atom model from PDB entry 1HD8 with a vector model attached¡€Resolution: 2.3¢€X-Ray Diffraction£€,FEB 24 9 Typographical~NOV 8 1 Initial Entry£€0€ € ¡€ €€0€0€ €¢€ € €0€ € ¿¡€0€ € ¿¡€0€      !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~€‚ƒ„…†‡ˆ‰Š‹ŒŽ‘’¢€0€                                      !!!!!!!!!"""""""""########$$$$$%%%%%%%%&&&&&&&'''''''''''((((((((((())))))))*******+++++,,,,,,--------......./////////00000000111111112222222333333444444444444555555566666666777788888888899999::::::::;;;;;;;;;<<<<<====>>>>>>>>>???????????@@@@@@@@@AAAAAAAAABBBBBBBCCCCCCCCDDDDDDDDEEEEEEEFFFFFFFGGGGGGGGHHHHIIIIIIII[[[[[[[[\\\\\\\\\]]]]]]]^^^^________`````````aaaaaaabbbbbbbcccccccddddddeeeeeeeeeffffffffgggggggghhhhhhhhhhhiiiiiiiijjjjjjjjkkkkkkkkllllllllmmmmmmmmmnnnnnnooooppppppppqqqqqqqqrrrrrsssssstttttttuuuuuvvvvvvvvwwwwwxxxxxxxxyyyyyyyyyyyzzzzz{{{{{||||}}}}}}~~~~~~~~~€€€€€‚‚‚‚‚‚‚ƒƒƒƒ„„„„„„„„……………………††††††††‡‡‡‡‡‡ˆˆˆˆˆˆˆˆˆˆˆˆ‰‰‰‰‰‰‰ŠŠŠŠŠŠŠŠ‹‹‹‹‹ŒŒŒŒŒŒŒŒŽŽŽŽŽŽŽŽ‘‘‘‘‘‘‘’’’’’’’’’’“““““““““““”””””””””•••••••–––––––——————————˜˜˜˜™™™™™™™™šššššššš›››››œœœœœœœœžžžžžžžžžŸŸŸŸŸŸŸŸŸŸŸŸ      ¡¡¡¡¡¡¢¢¢¢¢£££££££££££€€€€€€€€¥¥¥¥¥¥¥¥ŠŠŠŠŠ§§§§§§§§šššššššš©©©©ªªªªªªªªª«««««¬¬¬¬¬¬¬¬­­­­­­­­®®®®®®®®®®®¯¯¯¯¯¯¯¯°°°°°°°±±±±±±±²²²²²²²²³³³³³³³³³ŽŽŽŽŽŽŽŽŽŽŽŽµµµµµµ¶¶¶¶¶¶¶¶············žžžžžžžžž¹¹¹¹¹¹¹¹¹ººººººººº»»»»»»»»»ŒŒŒŒŒŒŒŒŒŒŒœœœœœœœŸŸŸŸŸŸŸŸŸŸŸ¿¿¿¿¿¿¿¿ÀÀÀÀÁÁÁÁÁÁÁÁÂÂÂÂÂÂÂÂÂÂÂÃÃÃÃÃÃÃÃÃÄÄÄÄÄÄÄÄÅÅÅÅÅÅÅÅÆÆÆÆÆÆÆÆÆÆÆÇÇÇÇÇÇÇÇÈÈÈÈÉÉÉÉÉÉÉÉÊÊÊÊÊÊÊÊËËËËËËËËËËËËËËÌÌÌÌÌÌÌÌÍÍÍÍÍÍÍÍÎÎÎÎÎÎÏÏÏÏÏÏÏÏÐÐÐÐÐÐÐÐÑÑÑÑÑÑÑÒÒÒÒÒÒÒÒÓÓÓÓÔÔÔÔÔÔÔÔÕÕÕÕÕÕÕÕÕÖÖÖÖÖÖÖ××××ØØØØØØØØØØÙÙÙÙÙÙÙÚÚÚÚÚÚÚÚÛÛÛÛÛÛÛÛÛÜÜÜÜÜÝÝÝÝÞÞÞÞÞÞÞÞÞÞÞÞßßßßßßßßààààààààáááááááâââââããããããäääääåååååååæææææææææççççèèèèèèèèèééééééééêêêêêêêêêêêëëëëëëëëììììììììííííííîîîîîïïïïïïïððððððððññññòòòòóóóóóóóóóóóôôôôôôôõõõõõõõõõõõööööööööö÷÷÷÷øøøøøøøøøøøùùùùùùùùùúúúúúûûûûûûûûûüüüüüüýýýýýýýýýþþþþþþþþþÿÿÿÿÿÿÿÿ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````````aaaaaaabbbbbbbbbccccddddddddd£€0€                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             ¢€0€ €血0€ŽËµ±K®¬Ž…±œ³©²Á±à°ó®ª[¶8º¯»¿5®À«œ§£¯H¬¡±.®\§„£ƒžøš}¥•¢­¥¡8¢! ?œÓ›«™×Ÿ•€¡œO–~“ žÆœà—H•F ’'…‹|Ù†?31Š·‡3ŠE‡ŠŒŠŠ›…Ù…»Ø|î}Ѐ3x‚xy®|Y||yªv’yœyyOzÂx7s's*{º÷}܁xŒnòiœgog"eñh `äi f d^*[Leûdýddª\ZVÇVoZ‰T9QÏQqQKRÙLxL NoMÐPÙN¿NMNþM3HîHÏQ QŽRRÄUÎ[K]Â]Ôb¹bàe;jPøQ•R*PGM(NñH9KØUVUŸX[Š]bY2RQ-Q;P¡LGwKKBRaRL~J§UëUoWõRWIÏD‚Cô@TBÒ=Í9=Æ4o924Ž/ëGGFªHKEÌIÐGLBÓIgLÑNÍLLxTŸUâJÆHÌMrL·RIVÃWVb[ab0hhûXäY’_RbÅX YdR8`He~g˜lNeÄd|eºgŠdBfa6\Öh aó]__cE[ŽXKW¶YÑUP[ñ\¿WqT‹_ý`hdohñc V@QZLšI-PºU WjVˆLHûC?ÚKµCM>·<˜8z?§A>ÛDÄ?= 7í7ŽAC>ÉEø3Ñ.¿.å/÷*)-%0$i!0i ×-u-U(T%Ÿ27_;ï=ž;Q7À;ã'9#$³'Ò!¯èÔ!Ø#  Æ"` Ë΢8Á*ÓŒ; ³ mÏfË$#c(z-W(Ú58J v ‘Ų -S µ O › ÆΈ\È% %¿x ý‹Ï ªC · ;ÙþªüP§ÿ.û«D] " nÂ>{ ù žhä ‚ " ÿ ù™öcôNöõñ@úöÍô¥ö¢ó€õ¹ò’ô®óžûÒýæûúÁûIøäó-ñ£ù9þŽHþ—ïþê¡ê7ççìí}íÜïîíÈñîìñöPó”õkðØïÐùéý¢œN£íÿé^ä±àšçÉäÄàqÛéØÜ>ØM×ҒÚ:ÛùØFØáÔTڑÙÄÞâÙmÝgáÛÝå°àÖå4Ý¥áÕã"à2à@ÛeڜÔòÒŸçoéŠåÑæ îó÷Œ÷%ûPâ»ßÚÖáÞåÞ»Ú]ÙÔ^ÔpØnÓÑæÐçÒÏ×ÎÿÍwÊÉÊîÌxÒ*ÈÂÏÄÏ̆ÎFÔ'ÓXÖÓÈqÅÑÇîÈk¿áŸQœ4ɊËÏNJöÎÝÒMÒIÖÈ-ÄbÆåÊãĉÆ-ËQÌÞÁÛÀ]¿º¿–ãß3Ú3Ùàá§ààá’äáÖ*ÑVÍH̄Ï>Ò Ï Ò=ÎîÊZÅúÂuÀϯÆÉËÁMœÆÀ ŒàÄÿÇ6ÈyÈÌÐPÕ¯×ÆÉ[ÊfÐÑGÆyÁ”ŸŒžŒLÓ0زÚ ØÝÜvâ ÚÐÜtÞ\â,ågá9á]ݳâVåøëºîðäåéFßÓí,òhô`øÆòî$ñò·ói÷'ïïŒígí3ëÏïúð ôÈöªëæ$áfæ·ö%ú¹aúwú›õ²û#Œa: x©êÛ8p-W)ûÚücäùlXy G LaúÎ÷u âF)ã š é ÜË^vkt(YÂÈlá  æ~ œ  ?qêøüÁü’û(û6øò\ïëøØþG€Ãð`ëê#ç êéhéè÷ímí=íˆë-ñQððêÑéFôúüè âàÞãÛõá2Û±åßeۙÜ ØXÛ¥á#â%àÕߑç¬é!åTåØáÑàyڎÙáÁ×EѪÐ Í_Î*ÎÈÏÎÍöÒÐËÒÏÓyÒ*Í<Ö ÌDÔ÷Ð ֏Ø`Ö5ÖÞXÕ»ԁÏL͹ØèÌšǞÈcÅ3ÌvÍÉÓšÖ5ÊÍ̕ÕžÚýÜÎá Û±ݏÞŽâkÚãÙ{ÚÄÛ`ޟÖŠ×#Û Ó¶ØØwݍßzÓËß%ãÐè—ëÓãîèí6æÊðõêŒïÃèŠìqì¯ðÛë’ïSìeè'èêçí‰êÁípó^ö“ë[æpä|ç|ôêúOü÷3ú ùkø‹ÿ;ú}ü­ü<ÿGúûôløKøÉùý?¯óñÊþk›æ HŒÿC€úpý}÷3øËõ„ð r ]û ÷k } W = [tÀ€Y  L CðMC,„2žç"<ƒÕT#-Œ ª?,•#˜"®"x"Ê!k&â%)j'œ%Ë#Ž#Ç ®"8)™,k+0GžY£–¥óû z n Ô bª=çýEü^íýÃûj ‰/& ÚXü#÷lô,ïgøSøƒùüéöñöÑô öPú`ô‘ùóò@óôþùvûšðYëÆîzùÿýž:Íúœöÿñº÷ëï¢óABqD aÇaA{þôÿ!ú èFx ÷þRø•öpõÚ ~ó<T s > 0q“ »À ¥   > i Ü ï„ ^  jÊ]l}µn7É?Ã!#Î)£+#(#L,ô2’4ó2B43n9ý<ò<¹;“BŠ=E<®76®> =Š>†B‹GšIZJ×3-ž,b*d)Û*-›&®."-*/Ê-ª.E)‰#ñé4†7H4Ž4ª<õ2#/q* (›.ô3è2ã6G'¯#&$’!± ’Á Ž)#*ù+*"-”.Î)È)$2/3E5>2Û9ª%Ù ³ÂŽ #Fy­îxä#Ì&O$î$,_.S/#4$ç#¹î¡%Ú&.$P#ö$u) s`Лzgh M_±öÚ FŒ^3„À;­F|§ à F ÃÑ ³ ÝÀ  ËEÃ Õ ÊR*ëPŽÏÕ{$ß%Õ(°*š-.~3 áš~âs1Š‘8 (Ì‹!<%Ò(]#{˜RÜ¥Šh&Û+(þ,5. *×-©)Z*Š#×!ö#¹"õ‹±}ñ%Ð(*$1$÷+þ1 5˜:Û;œ³|ofq† %j2 û ’  âM 1óê’†ý"ùq®þ˜|ý÷ýôý÷,ùlö[õô¬ñññŽðTðJíï í›êbê"éëõòËõùRûêú7þ6šØü›÷>ööw! € ÝF Ñ$øšÊä£ò à÷äŒ £‰W–€"é$Ì*€$j!~"†& )q%š%Ü'G$ð%•(Ñ.1`&!œñáÔì.å3©7û82{7C;‚6:ð?CC0DàDcHFÂJQHàL)L˜QAÒ@wCªD.:ž6v17]DÒGµM­PƒFV@þ?¿<::ƒ8=:é3 5Ž1ÓO€UCWVUaVx\>^ç^_Zø\×aaœ^ÎZPV[Oc-g dŒgujn"_È]pXŽVÇ[U_D\Ña'VÔQÝMÞL«RBVŒVôZfK÷H2B¿AÏHÑDbN?9ñ5©0ÿ99Ü:‹9C7£4q5Ç9Î1é-ß+†(-ˆ0ÿ'§/Š,7)£- 0“%Wïš<,.*Š%Ü0m5ï.&,9(°+È/ò)¿,0(.$[/n1K4È05|2Ò)&&”+%/8"’|"^*².˜04ç,Î-ç2*T,5-ˆ.ž1(©(À#]€!Š- ._3Ö6Ý*25i:g9‘5 =¬=Z=U?÷AÈAVCÐ>ÅCM>¶@Ñ@«9¯98Ï6,4E3Â1z6 ;2;y<,??þ@š;ªE$8Ä9: 6î4„5ý2È>ì@•A‚B¿E€AiBòE×D>@ˆJM!NÍOQÐOºQ˜VÕWöM°LÁHfYÞ^Ì_·_àcnf]ixmœgÅ__"ZUÉZUÐTêQ‡VsW'R…SCMöXÉXÙU;U^_Æf_eÕRENÛOõOµIE›?é=ì<Ó=r;SPQ)LÏJ V_[j`5[”K€GÆJAL@BÈ?é?=EJK‰FÈCCOÎM³GGC¿G1I×?ßFÛID‚AMO«Q#Dn@µCBG<ò9660ú@œBƒG•KHDL‚L=H!PÐQQnPU•T³ZY­]—a]URøSŒPïPÜYJ[Å\yO¹M‡Q:O„L'IäDLñB6J§EKVCZ[]M^“cPe9cédþZ‰[3VUìRLîM­KŒI3FÅD EIM^I;PQ3V¶W€PcJµILRDUZž`#aad<c_Y`T^Ña?]Š_keRh0g=ZcX[=\ƒRbO2\ˆ_Ýe$g `wcÖdgÞgÉgalk om{qs#oÚsQg`fdeQgŽbG`ôe\ðbuaxfuh]sWÜTUUŸinnlr>tÄpmm{v&rPuÝt~wÕu¡xm}vv~Ðz®q¡z quYopm“n£p nofuYwmGg€dŠdï_Y_‡\»x†~€dƒw€ž††ˆp†»„#‚よ~ë€ý~S€m_…tŠŠ„RŽ€ˆNycvktJrÞqÈs»utYw®vVx sfp[lÆm·s“w“zÃx¬Šh€d}dÎdó^ü_[ežfa_áknpl`1[º]¹]W“RÉQ3P‡_èb‚_ `µe”d `æZ'VaPÅNŒVeX0WU`N&H¬EmGMG™JÔKP—T‘@Œ<”;Ð<87'6j6j; :¢?Ÿ?oD<HõKJKqLôJ‹J²H‚CM^OËU-X¢PVR²R~N>V’UÚZ¹^6b”YÊ^Ìb‰_šg dBgð\^¹ZžV`\€Yš[¢`aZžXXSZ'W'RúY\žbud[eYzVÜR‰SNZü^g^‘NIIÚIOIîD¿@ DøHFá@ê=ÉI™OnRßRWëWÖQl[õU•ZÕ?9À517“;U=X<í@Ï@B621b3˜.+- 1˜1u'ì#„#]¹5•:F>·=œ:Ã7ChGøKO.K§MKQŠI$KpG«CwNS|V[ž^ê]—cöIOFhHŸMuF«E»GeF³BƒD…FKK[L.NÛOOpSpJ I°IÙGŒGEŠCr=×<G€F&JÔ:†54U0181ù5ï.Ž8¢8—>BD7_4&4ž2>4c=óB†FâEŸ@À?*>Þ> K¡P R…TtT W¶QIQÉTUX%VÀP©M”O¹H¯MEèH(E¯]`Æcdd•e cÝhœaed™gIlžm,d;_žghp²v#yrwæxUwÇuº{š~8£‚Ü„)†P„ƒ€¯ð‚܈AŒ8‚ǃèP{ÀwŒx†rш+Œo‡ý‹DŒw‰z‰U‹Çç’ ”<––—˜a†…ƒ …‚ƒø¶|Qyïv‰Ý5û‘g•ó™œ‡Ÿp'›‹éŒŠ“{˜óœk™á‡2‚†ý‚S}Êx·uäy®‚væ|Ò{†Á‰>ŒØ‰ëŒ×zhu¥vZx=q_tgt¡ožl¹yÓyrn•iÓjÌn%ewf6dÃhwevi_gÞhg¿h'b¥^¬jÆfýmêaû\ò[î_œ\Ó]]ÞWÿW VVTÔPÞOJ~QìUðVeYúZbQOMu\`7]¿`%bghY™W QÂO/VG[€Zé[aZPNK'GšHÒJÛMÄMýKCÍ@ :æ9>>äCªG\E`K!J8:3/0Ž1*r(¢+4,‘"®!k&=*û,Î(ˆ'27i7²:©&¹"Ö%­*,]$æéc#%%å"§!N#]¹ ,u*f+ò,·-P(z(Ì,Š$ß-Ã/4Í7Ž.w0×/},>1Ú6R;{>ñ=U;v@ß7íC€FÐL]O÷FìA—H@M4RbRÛO!W¢Xï]8`å[šX=\õ\œ`rc` ^.Zqb]WŽhNk«nÂq‰osløj\mpmøp«uAtƒm2iiîd5f$`gaGyð~›‚;‚¶Ù€e‚€Ì„ˆ„iˆŒ]‹¬…‡ˆ‰ ƒž‘.•Ð•Œ–©–£–²˜À”†’⒍¥ŒŠó†Šr€é‡FŠs‡CŠõ‡ê~xæuÆtvxöp‚tËqÒkôissßyt|j d}c×gbU\£XäZÎT_‘]ÜXAUy]ÔcZc4aeNVðQµP6SPïQ•MÓNƒL3HxM­K5II×HêCOBsFúKßLHGvF¢Q ToU§RpDz?}?;Aç:Í::;k:„7€3Ñ7ô6‚;±9C6D2.{9•>AAN¿3rÄ2j= T‘ WÉŒ6Ä.ÿNÓN +  ûˆìjÎÎÎøӗÁ7ÄrÈÆé]-÷8Ýðî ãGŸúù%à)88†éùøe‚n4BË,Ì<Ý)U'‰œ"’êûüþÍ,yLÕ«#µ#±ò0ZLžbJ-ò* %r?×H5H¬Tƒ]jò?FáUÍXO<%OžGPN÷SK[ºmp‚yÓwºŠX„teXFICˆGbNv[=%B_Å2KEá:X `µ‚Í?‹C @…1#$Ö-ù`ét²bjN$KQA\:b#ŽÏ¢€0€ ¬#¶t«ûÍú÷r ÈôÈÝÜòSu z Œ Ø “ R­ÉYäô0(ý0øõŽò òì× "þ‘‹ ÜÜ[¢T±ÞÊP›Ò#f'¬¹%S %ª"&*+e+Ê#G5Ï/q4ž4ý2º7¡8`=@û94†=Õw8Á7ÐIÝNæO+N.SšT7T³T‹UZOþOØULWL!FŸL@CžWš]]]ú_¢e}gvgÚ\\\Ê\TVÐ]Ê^šY‘Y€aÁd}iÿlpkƒU‡P©KñL(PRÑG¯C >e>õCyC_>˜Gö>pGãC+CJ9Ó4õ0Ò1ƒ3Å/.2¶.,»(~#t#f(›%ý#±":ím‘6D å ! ü Ä #ð þ8Ù­Øþ|û•ýâûAÿ@úmúÝøÁö ô2òQôæýfý 4þ-F = ce ü}] € ƒŽ õ‰;¢m2!¯'2!d+­%@%öz°g)&.—1«0E0}6 9>•?I68q6&1Ç8®BnGÑJgJØJÐPžSS“T•LN£KwMŽT&WäXVZÀFyBµBÌ@Í=PDøEgJóKÆCk=±:gEuO^S$HÇCØAŠ=CåEŠDCC[E C§?©< HgKÀFè?­;Ä6M2x=XB£DIN5¹0Œ-ì)+0a0ã0ã*‘0Î.€-`)†1í/i))³0ž0q+q'ú5C9Ä4}*%š ÔŽ& !è!O?v‰C?6xh¥Ôã•@"ü"%]RâNç8#C'=@ á  èjè Ð óŒ‡ö ÷ 2Š'ºéþ¥ú„Ú á z˜þ¡ùž÷òfú‘ööÔóóúù®÷±öŽõFûS÷CõÿùÒø¹þui)(ÚzšµYJ  Bè a[•fA@ üíü‰öÍõíú.Kµ • œ\gtô‹Ð– 2èýI Ó ¡Të ‘(™sŒ§Ÿ\uä¢"B&:+- 'ø,­#œ,ô1Ÿ6›771 ,y6 ::? BÃC~AÕ=êF;EH¬MòO~PÁU°UyX×W¥S¯OUaO;K÷NúQŽIÄD?ýBþNhQ;M©IT,YM]#bf~PM±JKwRyVeU’E—AÜ>F;I>›:Ý5ù6=<â>úB<ˆ1ˆ,À+,*ã(f(¢#Ó!¡!ý*)B$s$D-›,«3 ¥S âÞ# žº„­Ödê9ªõ?»LÞ#ý(+;&#%ý*Õ#'œ+Û+W/?+ü-Ã-`3p&x%r%ì'º 1  vw%;&V,9.+#ã+Ù¥ ¹ ®/A4ç6:z7Œ=D>‘@À4$5€4#7‡35r3b3e/T-8/<1''-%!( /³1á7×:b/Ê*d&M)„:?™BòGž?ÃD„C“F„>ï@mC$F„JŠFaBòE$H:HÃE)M°O@MåLyUVsTZXN L–FèE­M>RþVT C’=ü<Š8;…?Q>A? <3A³@’C?Dt@~>CJKšN?;J5ï3%;P4œ/³0I,-§+é&~" 4‡4q3i0t9Ä665w/ë-ç8ú>¯@GAt-€(]$w Œ&!w o¡«çß%S!~"|”!{'a(**ù,+@,t/:5"7ß7<–=X9×?µ>:AÙC…C1A]IWIÿOqRhQE E ?œ>‘H…MäP¡O;è6œ4*0ž3<5Ç3Œ5·2Ž523¹-–0ý*ý,œ:Û=E:¬9åC8E¢EË9X6l1A/Ô.w)—*F'D&Ã#~!Sò.w00‡.O5[4º:·žAR+ '$#w Á$à!ò#Ž ”"ÝÀöU?O.#'ý*[('0\2š2G'{%W€˜&ƒ+õ/Æ,wŒ0(EˆŸ Ì¥>R™Ÿr$Ÿ&)'U,d0C0Â.")ø,]'v2×6}<?v5 0³-e(Œ$==ŽBåD GkD~E0H‰AïABBù@_=<”= FRGžJM©KL=P\IŸP\LcH5IãLÏKíEABDí=œBx;=’OÜRÍRRIXÂZi`7a¹c€Q%PXKˆInUUæZIŸE(FbBÖBõAæF•KWLòP7PšO®SºSêWÎWöZXRÔV/[n]Ð]—b€gvkác|aãcVd?fÓj³jfôkjŠkhinqo­o€l6trVpõkZg-tÒxpzåxk-i[cóbD`uZøYµ\KY‹VóY;X]UØTõO@K¥WšVQnYOÈWbR×Q N–I¡J}NÑFiAF•F»BÛ?[E?ŽCy?ì:P6™AÁ9p4P2-}3Î..-B0à/à+3Œ531ò-§774Œ92534a/–,¡9š=N;>>M.N)‹$¿ ³)z% ÛÅF!É!±#„##á#‚ õš(è*](©/ß" ë| Û [ œ H  Õ2Î æFåo  #-Ê  4¯§ª 65n¢ÿýoùÇúàûÒš šWžÿxÿûˆ¬ãú˜O‘q‡¶ ýçýýß‚÷~ôàù3üìýàŸ`úÂôãòØñëÏ €^W…×8 —   Ò5F œ ÓÕ<äŽ É (—‰ô.Ð6¬±¢ ³ñŏ%!¢'W$&g&ÇOõŠ éÞªD)° "çç0Æ&##²'\,!•ŽOÜ%$'³$Û /'N++’(Š/ 'š%W(÷-”$)4-e)o1·-®1Ý'*Ó,·)×()#@'B1µ3Ö4œ728’9‘5–>‘6?•;y2³3Ê4x8=9<;J8I@1M2@6}8!8B<997O@ºCDËEç8õ6‚:6>ñ4ñ/1-'t$Ê'#Š8:b7a2“:€=ÇCˆFŸE :z8`7ý;Q<<'=ÿ6ì493þ8Œ9ª/ .1R)9;{@>ñBeDFÉI`MHRSU-:8”7¡3i3ï1ò4.;Õ;‚7+4ã5Š1d,)(ä0G4”3‘5V+1&p%å!m&~%Í%Ž Ã)î)l)l)a-Œ.,Ó/©-’/W1Q0œ2¡29)Ù)÷$u ÷+Ñ,€(Œ1#ŽSt¶ ¶n!Þïl•„#>!~î£j!ƒ&Ê^¥éÕ À‘ Dê}Ubê ,#€"Bƒ£‘x¹ Êt ¬Ó%';&û) .@-Í()#r&  32c7);±c]a]¿clegeÕkTl¹qEmõmmjl‡j$hÒiQi~k[gÊckûfôoiàf‘b<]ûiûfýfe%cŠbaŒcu_Ï[‰W\bècWhÿjøp¡\`XURUœS?MGKS…XVXrU}U#WÙR8JìE‚C÷@DmEDDICìCþG2FLEdAºJ±HUGwB@K™QLQÚRQº@;"6×3:†=Ž7ã4-3Ç/z5Â23©0“2š7ã7…3Å0„<Ê@6DéIÏNF4ž1Ú,(ò5 4Û5r95*€%&"*÷%/'&Ê#­$e"®"&Ý%ê&%%Ú%U §¶*_*Œ,)`+Ù)ø'¶)K&í'ª ÍpÈéóö n§/ H“ Ï A š ô~Îm ?$®'š&™tí þ š;Œ>C<"1 º ‘ pc éìjÁ4@üù°ùÊ÷õõiñhî)ñ­÷°õRïzíÀ÷|ý ôðì“æåäÉæýä}çÄã‹ßðÝ:ØÔܜٍÙ§ÖÝØEÓÇÏ<ÊÙÕÇÛMÝÐÌUÍ~ÑïÌóÈŽÊ-ÛÉ€ÊÆÞÃsȀËrȗÉLjȂÆ0ÀkŸêÈËÍŠÊ>œ)·›Ž¥¯Ø· ³ó²Kµ­¶æž6³~ŽV²r­†¬®•­ÿŠ€£ž³œŸœ&±gŽ8°Ô¯é¹ŽŒœÛŒ†À3ŸÊÀŽ®Ó«X§§}®£PžêÂéš—–œýœ<—­–/¡j£ë£ä§I 1”鐳“—Ž-’Œ–‘EŒëˆY‘e’P•kŽ8Š'‰ïƒ‹ŠˆŒˆ ‹iˆš…P†§ƒ^„ …Rƒ«„…!†[†P¯Šþä‹.†›„ …¢ÿ|ꁵÿ}†ÿ|ýÿy¬ÿ~®ÿ{ÿy ÿz‘€WÿŸÿ„ d…@€f‚†‘‡Æÿ}\ÿ{ÿ| ÿxRˆ¶ ‘‡Ï‹Uˆÿ‡~ˆˆ‚‡_‰®–Išøzž5žÈžb¡c§7šþŸ9¡åª¯‘³i²|°{­+¯d­·ÿŒ Á;ÂkÃéÉ5ÉpÆwËÊÍkϑÍÍ`ѯÒÃÎ ÑÓԮќÔsØŠؑ×ÜÞ9áqà¯ÛÑÚ5لÙçÝ¢âÛò×^ÒÍØ:ÛªÞøá¢ßAÜ'à)Ù-æÞêIíõð¶íŽê…éŠènæÃå•äËáýîñ£õ2óî»ê æÙëÍú ý£þÃ~­w…ý ýaÙ÷ÒôÅôÉðdMÕû†“¢ªþžûâýã£þ[ˆ=þYùûÌ÷ó„ðÝí}ñï êQèÎó4÷xùí÷PòŸïÿðäçÚãƒސÜoâásÚÎÚSÝYØÜÙÄÕÞ׳Ûڑß3á“ÞrßÞáßVäJã¹áúäÖÞ¯ÞžَÕ^àSáÅÜÂåÙµÔÓÔëØÚÓwגÕ$ÑÂÍ¡Ð\υËkÇ1͕ÌÇðÈmÌÈÉÍÅBÅŒÄÀ»ÂQŒv¹¹ÆŽ$Ži±©¬JÆĜÃÅTÉÍAÇ.Ÿþœ;¿¥Á·FŽŒ®Ÿµn¿ÎÂ>ŸpÀ7ÄåȄÇ®̕¹}µ¯±•°Ý³Œ³2¯ªùŠ‡€Ø©2ŠÝ€@ŸÉ¡ˆ€~›tš™œð”k  ¡—˜’¢$Š‰¥š«ÀžpšÄ›BŸK›Šš™–íœÀ–îšp–Õ—™5—Ö‘¿š›± š€Pœ›ø¡¥®Šñ£h¥¥—š  ’«»­g¯5±±ä±$µBŽß¹L®×°Û¶Â¹Z¯»²"±=«®«âžÉŸ1ÀĘÁøÀùŸàÂ[ŒƒŸ¿êœ¹aºTµÚ²v¶ ÉÅÑÃÂmËÑÎKÎ}Á Ÿ&À7Ÿž\µå·ØąÆÅËnÎ-ÌxÐúϲÍÕ(ÖzÚÑÄÑ2֘ÚŸÐËRÏTÊ_ÖbÚÿÛ ×WÛ%ÛNß%×Kß6ßëãçšáçÞÚEÞ Ö·ÚrÖèááä×æ&ã]áúã’àÛaâJêÒíïñóðÃñ£ìmô„íúð ïKòåõÜ÷Úõ2ü>ëEêªî<îŸðÇôCñÀðùšý\þ¿ÿUñ'îäó2öíìŒèLë'ò öÍöù¶÷_ò=ùýòîñŒð:ë+ç£ïqî#òº÷=ñûëæÈå_èúè\èŠêQî‡çàZތÙÿ×ÜÓàœå.èÅèüåµìÎÙ¢Õ{ÐGÐ3Ö¢ÛÙÝÌ@ÇÃéÃRÄ_À>Œ Ÿ Áñ¿_¹‘·ˆÂ)ÈÁŽ¶Ü±K±³Ü®±šú¯®g®„ª]ª­­À±f¯ß·Š¢n ™ŸÆžšDž9ž= µŸyš/–cŸÉ÷ž Ÿ,œÔ™ú•A”k–«•T•z—…‘SŒÓŠ-Œí‹JŽi)Š„Xƒ?‹Õ‰0‹õ=‰®ÿ{ƒÿx•ÿw8ÿx+ÿuÚÿzGÿ~¹ÿqÞÿlÂÿh·ÿlËÿy#(€*:K_xc‹K6JJ?§üTñ{ûÒö,îÛŠv+³6 Aø*ßLrJ÷J7P$Lp\k`7[Y­ ¶ôƒ0c:Ÿ÷Ê@pQÈ\áUú]á5TA~Ÿ5•>îA$OFµ°åÓ-·2ø*p;Ò0±>@m;}R«dÂeäPž^cÛ4”1²o,OŒÙ¿ÔÌŠ3¿D” œŸ„ø‘¿žÛMásørýfó>ËA²šÍ©ò¯•ÈÞàÏ>ú¹ö¢íCÓÒžx“f‡v£€0€Añ>9Ä6A€?Å:lCŒ9ý8`3<2ç8Ï<@“;t/`*š*«(3%ö!$%! ..Š1Ö0‚10œ+Ï(Ñ#69É9a=?*?@253Œ2Ô0$.'+Æ$Ö"ò4Ô4x0Ž1D9É:„>Y7Ð,w())s,²#å&­+x&é'’#ê­%œ"äL ¥&Ø*–*[]¡Fâጉ—zÚl‹ "µ°GòK£Æ\Š^ïYý + \ ‰ÔGÀØžuÇ$`'x,%o*š*2%ÿ.!%_(0$™ -*»/u&Ý#¡'N+ðu!À"ä"Ô$õ$ä%ï(.%'×#ª]+§.ö(ƒ3Ö$¿!7$(« =Ì# &O"Ø7)’%ì,Ø(d%7"v#9'£$°!yK"™ ö"i%—IÓ:5-O!æ$Ý*w."#w“+x0Ð3þ8§1*/1T3Ó5Ì8*4Ž64D/§5…6h<=B¥7_5á4S7“: 8 ;B/]-W-x. 'Õ'E!À+%,Ä- .è-u'é1ƒ3X4‚6ž8!<#A{BDõ384£5u1º0Š1w-ç/®)!:,;Œ9€799>:>F6 :›8;8ì8õ?®BÌBáE+HeH9EUK@?ö<ß8l=œ<äAm?,<™848Ô@DHMK*OP“Q?3«/+þ,É+±.*u(#±"i l(>$’ Uý"3ŒÏâÇϱÖ4 #L©Ó6¯ X[à!wÿn i¢Ð`î/R ÃxœnôFœ K  × -^™ýíý<þ }¢x2Æ Â2I„_7î'#5%0+ž©á¬Š8: ® ï  w XA^ÉtËoa†"  M%ž$Å(i9œ-âtÇ a Ü Ê JO Œ ÞÝ õŒÍùö!9 $ |ÐI³= U=/ ÿiùú âŒüÜÁÁ.ê”& ô  ` E €ÍGœ¹™ òý¹ú^ühý‹ªü«žþ vpõ@òíåíKðì»ë'é}æ.ë>çHâÉàdäüèŒæjá™éAá¬ÝDÞÎÛlÛ&՗ݑãÂå2ãxãTêûì÷éÌñºâ§àxä‰èIÜ.ֆÕ¡Óœä:è@åÂáÆêìî€îèBæèbíæÿäå>å çèúæ-âŽßÈåãfíŒï¯ñîâôšöËùÈüÈú‰þ¬ýž}Ó!Õ¯×ÚùÚ¡ÜXØ,à¥ÓÄÔè×cÖ5ÐÏ˓ÊmÈSÚíݝÚwÖ,ß8àœܜÜÌښÖ~ÔpÕÑaÔ Ù^άÒ3άÊÒÒ'ÕÓÉÏ9Ô×q×1ÓÛ°×××Ú<ÞÓØÉÖÊ×@׶ÚdÞÇއÖAхÒ/âºçåYç'ërïoîNáœßÏÝàß6ÛPØJÛÙ1ÝsÝgÔõÏÎË*Ê×Ç1áXåUèàêÆè€å¹éVãòê1íWêDìœð8ì^óÈïSå;ââ7ãmܯÜñØ)Ùs܀Þ­ÝOáŽâçoç•á‚à4ÝáÇë™ðªñò†õõúuùƒð$ð¹íï$ð’õøyõŠè"ärããâ¡ßÝgàï×£äEã0çÙç­ßpÛì×ZÖ<Õ&ìð¹ïÐòQò³õÙìrë_ð2óñõ”ôËø˜öŠøjûçöðîÛðTóŒéç¯ë}âîî îõôšöëfø$ý¥QÏ}‰þØþèûÿtŸùø÷ËúQû¢ñëûdýûš“ý‡ø.õãû<f à µ2q ¹ 0¯ ãñ QŠ Lfþ2û§ùû÷@øÁöÊ © mÄ| ²bãŠz‰àœ`[XXQa"`Æf SÑü} ¿"Û(`*~-ç+()*%;(á*Ú(§+T)o$ !•$–&eÔÓ×F9%Ò).X0‡)ª-$j0‡5[4ž8q0r/i.£0Ž*‘+/%ÿ.ï, +h0Ž1–(€"î|®4@9o=@Ê< 9²897<#?­=¡@µ@ß<¹8¢6W89N0‡/0B,Š.Î+D,S*Ê8à;P@³A·;Ÿ?Ô6?CêIHâLLÒOMDRôE D¹CDŒAN?ð>8B™B 9@4Z/©3ƒFŽJŸI£L"E†DHXJ>Ï:5f9ôJ1NsL¯O©ReVXP[<W·GæFA=>AE!JIM\K?â;]<á@b7ß6 3::€53w?a?ù=xBŽ>­AÝ3š.²/”3¢*ø)q&+Y$Ÿ)å&”+Á,'@'‰,É2q3,6N00"òû0“dçÖ(9†WÃ Ò A E ÖÝ­   ÒµmÖà Œ õ% ¡~Èþo…ßÚ‘}2a}\ `[ ·&''î&s(ï+G(R0,ý1ð48W0G/º/,*Ÿ&|!7Ë262S2/3H7O<*>Š>:CBªE Im112$3d,-ž1À2{.¡,¹7ñ8°-v*+,>)\)È1:3y2™0Ü9;;"@ìBÚCtBdE3ô3[-®,ƒ5À;š> >M* $"3õ!²"Wh"3#ÿ"n$¹"K$l)B+Í)@(?1¢4ø:4î'(#àÄž"Ï'Ü (1¬ä‹ñÝ#%*“.E+‹!"$è&™D U  Œe*  x ž c ˜2)JŠ¢"ú(y*ý-v/A.}1ÎO W%f&w(u4 HëY ²ŠûÊþ “ÿlú–ùëõnú„ú·ù}üOþýOûŽ÷À4þ-ûý0þ‰ýƒøõz¥ÏŒþ$™ýþíþõŠðBìKè îºí§íJéŽéhå>ë]êIè£ííqíOéŠèŸò­öœùƒ÷:ýúµý•(çãhÝðÚiãñâ†ä!ä§áÝcØÖAÙ×}ØØþ׉ÛuџÏ9ÌÄË÷Ë ÍnɊÌIÐ ËXÈaÈöÊ Ÿ¿1¹Žž0·È)È$ÄÜÄQ͘Ð%ÑÜбÔÓÔµÂý¿ß˜àºžŒa·[Ä ÆÀüœ}ÉPÎ&уÏ_ÕÜӿ׿ջQµÒ³Œ ÁsÅ¢Ž ®å¯ž¬ Žzµ—ž…ŒÅ¹·¹ž°²ª¶žqŒx»ËŽJ³®Š®©©¥©ŸÁÅ®ÇÍÈGÊÉÇõËVÃ`É[Ë|Ñ]Ô5ÉôÄVÄpÁ†ÓdØùÚ<×Úiàã>áèގßVáàâ†âÂß²ãØá>âþç‰à#ãæâßáéšìtëÅï°áÝޓÚ°ã^äfáóáê6ìáò êà™ÝçØá×GÜ@àdÝîãnÕàÑ ÑÞÎ Í)ÊÒÅÆÍFÄûɈÒ8ʎÓCÏp֘סÖÑÙZÝ#ÞCÞ×ÞÉÓZÒÕîÖ`ÌtȜÉ0ēÙ ÜÜá†ä Þ±â$âÐçTåÕá“ëíÇîÝòâéRè|ì]ð‹èÙå—à×è4êãîì…çÝìáîâïðî+ññ%î®ô÷üô‘ó›ö¶øŒùûýŽû¶÷ûœ#8 Ñþ‚ýÃþŸÎ)þúôõ]úŽùµú¡úô ôð‹üýžþžúýý°þûÜøÓøïü‘õÊû»÷œum÷¢3  Ä Îµýçü*û?‚ÐýŠEÅ-­õשÁ™} Ü(Ÿžró ëˆûqüJöÆøËòúô ðžT ¥xš 2 ¢t  ÚžþgûFú) œ4jœJ©è zïŽXþÍúoXP;üMþOèúúpûÜøùôžúšõ"ý<û˜ù’ûþŸú7õô²÷-ò1øÈú“ýƒû›X„«  œkë… ˆ è åe 8ÈD£ „ c œ ž æ ®rŸþš ¹V 1~xJÊ 0ì…‚F ÇÚ ž‰þíÝk@Vó˜ë(ÚAÛí¹Û!…"Æ‚iLú# y aá õ’ò  €Zó’é!ÿEùõööÊø+øû¶ñ‚íuëŒêèÎäLäàIàÜ+Ü ë'èøìÂë)æœêê’ððÞñÀõZöaú ó=óèô‘øï@íRè;ã·à{áqÜNð¹ïäñô<êè“ãß~âEðžñÁ÷qøï”û’’)éû×þ•ØpÕC§µúüø0úúûÃò…ïZé¹æpàêý-)ÁÈÕ u³ £ m Ä™3Ý}êÄiüÅø8þƒŽyÿbÞ&ûöäú[ Äúàæý¡î!Ó 6#šœ1ò  œ I D`Óöùÿ*±àp œ nâÉ£þÓäúIÿk–ðo  Ék÷{™ !#'Ð!‡+1$Ÿ)›†7a#MÔÌÎye€Ùlg•"K"ð"M%t)K#Š!Š)t$&Ÿ(ù&›"‹$.(Œ ^-ž/Ø1T0š4t590¥2—4h2Þ3r:Y=üC <Ô0ª/%2ý5Ð)•%¡ q+":3M6ž5<0¿5Ü8ù0"9 8j7_7~6©5Ÿ:ä>:2„-:)Æ$[#ì;)@ @“=S@}EÉF:G„EODÕEŸIGpG–IFNÃGÍPMM4PËRCQIUÉUEW,\•]S=T‘`leËh"f<h„lMjåh lÊkÉn}qÞtHrsBnOqöuGySwðru³mÈ~$ÿ‚Wr‡*‡Fƒ±‹0…(‰ŸÆŒ¥’¬‘'ƒ“„£€ ‚z‰Ž /””9–${šxtmuNpqlµhÙeXjHhÛd^kôhÔeËilØ`?^õg†jh8jKk0fbfCdaj_ò]Ê\T]QXX7T:OXUa_ºZßZXd?VêRmS¢U>MÔI`SÎU*P©LÄYQ^Db `ÖQMO S›KXK_I€F GÇBnJýKPIœE¢CÎMýRJRbUÆD¶@é>g@‰B >Û9 6Í1·9k6B7ê9b0ó-¥/b)7b8ì4?0{·@Ñ4W0Š3k7-|)’$³*É! '"T‡1i3é/ð+™6Ý:F;„?W1w-ó0!4z-*0)®-B/ *Ã&=/Ý*Ø46)ÿ,(>#è$ð+j0ï1A™ïÇŠÈ ù ¿ @Œ K(Oq7"î'É)¥.0,9+x064§4Ö0‚9S&`'I)-n!»Õ[%}&í(A-°/é$]#ôy!ï/Ú5>8à=œ5æ3‘6•.ú6ª9ý<ß:ž6È9ƒ:õ>QBDâGþJHKsOŒSbVHNKQOtN#G¡TX[HZ5ZÕ^Q_b7gÊhª_õ`Cd\"dž\?`™`Žk^pÜr•pßsÎu­x{u¢w€|ò4wórªsmo~ȃƈcŒ­„p€H~ ~ÿ‡3‹eˆñ„BŒ‰€ŒŠ‹ˆ$„_CŽàŠ)‡»…²ˆ€‹ÍŽ\”%—&•O€óåyLv‹pºw—„†ƒ)+‹ê*Ó“Š‘\”󂈀ƒ°‡à}þÜ|çz§}S|î‚q…Ou€rÆnÈk×oêr)w‚rKn—jÓeäeâl±q“rƒvRoJa\£][_šX/S!NœLF³[»\4aÃbÖYSYQ0PLeWjšjHg:nAs’w<v{Ïm—mcquƒnamÙjnosEswuÞqšr kÚp€p–mkëk`hIdaeÛkÉoðhŽ_È[š[[üVZVURJQ8[‚[‚VhU`e^f­h—SlN}OšQóJ)H›DßKCmIŠEÁN8O‚JýG SºY*]‹]Ba…KGöJúNDN>ö<;mJZMRæUóKÕFTBÏEoTÜZw\I`ðX°YúXaSêWcZÁ_›dHh~\4[X[5_ïaØ^ÒSxPìQO¥K?HTKKB†R“RÀUáUæMOLgLdLÒKìXŠ[êZWX×a¥cåijxlãZ^Y7\Þ^ËSµOMOßK¥GECã^aT^…YåaÎ_d[ò`ö^º`ke$`ú^bbdYa\º]Ë\>XÏ[2\RUZ^²]¹XªXEbpa™gTŠOœOÁL”JÞJ E>I£SSXz[¡O5N*LO°GˆYÌ^û`ð^*^ØcÂc:_gLeËhem[qci@cÿldimqƒuƒto]jhUzs~<|ü{[ƒŸ‡†ŒŸŒÌ{|×{\€5€›„'‰ŒÝŠõ‹ˆŠtƒ‘€<µ5Œ1? <Žþd=Â"¢0k‰Ó%œ7ʼn@Ã7ãA°3_5š@²E³1~BöGÊMŠ2ñI}Hçüƒ2‡*í ›MÅã?òâ2îìžæH÷ˆæéØŠøùž‘- @ ¡+—A—$Ÿ5B=¥CŸ1Š9pPjTúG€0Ù&Bª"µQKA¬>ÖGP6Ù/éh'jû~gÝÑûÅý î2¹Ý1ÍdÄEÆkìÓðñã?ß çpòµðôðò‰E ÇïxóÍ ì]éžê êÅø׆ØáçWñ#ó·õú‚'Él:?sOz`o^ËDÔIK >ƒ:q}ƒ‘œ„5…|~*rŒy©gìFF=É:WSWQUyyÒ£€ €0€ €血0€¶uºq»k·¬œˆÇ×ǺƬœÄà¿ÖÆ>ÍwÑ-ڎպµé³~Žµ€³’³U· ³AŽÒ²y¶žŒ¶ÁÐ*Ô&Õf£„™fšˆŽÙŒ•$Ÿˆ› Ü›ÈÖ¬:¹ÜÉ5Âj™4›c’Á«¡…Ÿ$¢šë]Ö‹UÖs?ˆ‰a\‹â’SesŒ<‘‘‹–'‘'7ÍŽî” ’Sš‘ Ÿ‘ù’®ÀíÌϓÍÜŽ†Äwâoó‡ˆ]qˆ@rsq)plÀxFzwL}–eÕm$sªe5icwØ„~}å•õªœ¶žž›r‡qp/j6}(…µfîfkbpXÞk0sœuÚu%{}Ÿ~êöZúUPùKœ^ÿ]WuavS a²b XpÆwˆ|}‚VTRÐG®5û^¯fÏ[ÁoOÿYiVþHã`SqÝ~ho5_ŸkÆs<uÏoÌvxx{¡}ðyÌzWwUnxmÎm7fpão{—^jhÿbp\:RŒb _eþc7bç_Ÿg˜iFaTáxF}Š—–m€$Z aX`Âb=^.e[6^õi ol—f”f/_fm`m$r7j6\uš~îv«|`Š—‹K’Á„~†}<s'‘'î°™¶îŽªzŒ|7||$wB{À}Ü~®v«}n|jzMtÁuÏy wõuÏy@„aˆ£ŒqÓr#v mjt!yeÁzC|ásæwi{„ƒ^„ø‡O†‡~êƒßpbwyo…}Ž=’+Ÿœ¢Š©i ðz§‚zMˆ’…–æ–'~ßzWrLn‹~ô€ }©{[{{ç{ {G{zyIqH‚‡'rVrÍk±Vqr7uîk÷nÒhŠ[­SÊ?*\§`™T$SÓ\0güi–b=eÕkw{G] [ÖRŒDQY`…eqVhQ­X\\÷aí\0iœr×gyXŽZŒWXQóVËXèQ†[|[TÍQ"[VJOâO_W²N>B"P³QIRvLÖZc[@PùZú]ûdÑY_]4BXHaŒk\§føjre+fDf%g>^.ZP]¡i2ožk”ghBpÆo5uîrÃxÒxOuu”s'y„u†Ør#u±u±jƒþ‰ãŒ‹“l‡æŠƒ"¢QŒ1‘–ë”y†Š“0—,“3«‹ˆˆŒcŒ‘m•`žü§Ú‚<~£xÈ~ß„ž†8„í„øƒ^ƒT‘Ÿ‡mš¯Šr­4¶î¶M”>£>££ç¯ÈÃYÒÇÚ4ÚžñŸs—Á”G¥ŒšÝ§»‘<˜‰—5™ñNŸÄªn¥F’!Œ1‰Æ‰î‘ùš}ši•ìŠÀœ•áš#ŠQ…f†º›wŠ›å•áŸÿŸ‘žÓ€£µ­ƒ­=¢ŠC¢“™ƒŽïÂÊÚÊ:ÐÚzÞMÝ?àÿãçáÒŸ<‡’Á3œ×¹Žº†žâÇáÎȂÉ@ÐÞÚHæxîQò€ƃÈZÈÛÍÑÅMÆÔǺÄ€ÂÿÁɏŒp¹¯dš¡¿ËÈï×Ûп«6šH PC«…·)º®»ŒºÖ˜ƒ6y†œ‘å‘x~6{4zÚ{zzÚ{=y­î}~+~{û€ Œwsx–„X…ûƒÌbsǏŽ£R°™¿ßµ@zySunïv¢yàyÂ}nsPx o+h#|ºyzlu:s–~hƒ!ˆž0~…y«†L‰Ïƒ€†›…[„Dë„íŒð†Ax(o"r‡nÈh’aÙ[][w.yuø{[y,rœr}lzw¹}ðy]}Ez§lGs–‰:…µƒ—!¬W¶/¹Â„ЉŠ4„ˆÌ†‡I„0…À|õ‚ÇŠoŒÈ’óˆg‰ÚŽN‰€Žî”*\‘Ÿ£¡³¶»ž„v¿nOgüsPkMiŒm`iÇk&kíkCoTg¿`…rát®pã_Üg j^$\äiœ_ï\&^ë]Q[]]>QéUdmlÞh8dPlñyÌlÀj|}1zÐq—Œ käpv[tgqy}©xÜ{wì~+yÌy@s gycuf%jókWpdðq¬wBv*~Ë}ŽyÂuÚo|v˜~ý†i†8€yËš)¯¬šˆ@†á}©x—5ªœ­üµ†q—iFg>bÀXH^$n rÍdnÛtšrÃq¶v*s1p²nÛlpjg] l—eJagè^Î_OZð\&dÇg `ßbkCc`føjIgÉh~]ÊcºZœS ZÇfkgnZpleqfXf/`moÂm¥jÁnïqfjÖo…pŒh_s–wuø|.w$~Tƒ‚xr#w$|wrsðq¶‚ùŽ%‹â’+¡êžUÂÁ3‚‡'‹Uˆž~]‰WŠ=‹¯’S‚<€üt+ƒ{Qˆ„²k„ž„0†ì‰a…„„ž†›„Ù‚ŸŠz|U¹›1§²Þ¹úÁ*pãnjc7ml*h¯r#o|pCpšbv¿wœfDrjutàs‹wixŸw¯x{À{zmØk€p%gHkíqmUtÁrÃyr‘hØsœp²d{Q€¶Šo‰î‚ªnŸl¡q=gÉhÍ^j\aswwÎs lx³„MzŒx©}‹V}œƒgŠ[ŠQˆT…À…G‚‹‰€˜X” Y°»ŒÇ¬³_±íŽ ¿ËÂA°¿ßÁ ÆÇ8Ã'È2ËÉͳÓȓÍdÆçÃÁ„Ê÷ÖõÜðÚQ·f°ž¯<«Ë§ŸV’JŒúœšžÝŠ®_©Š„§~™|.x³kíklagy`ódŽgèmUvwBw~xYlñežsmi(lzd–cVšj|[6P?[^õSÝc7n©q^AhˆgòqÓuî|›s dªe®fkdÑaM`ýbÊ^›[à_d_‚Sü]èb W²f:ZÒTºNAnQ]JŠP2WbTjY#_ùW/]ÔV!UŽT›NÞWÙVßUðT-RãLýIÓ?ÉSÓ\kbü_ŸZb¢e{oé`ÂdFZYi[àeš`Â\€e@\0fuqçtk±aÐc×e+fžoÂpNdðojósPv[tàv>y­âŒ©e‹UŒ–oÕiŒf»kle…f/jjš_ùgŽ^›cŠ[,XHeôk±mºceÕgŽnÈt6zMu:w.’±šÀ¥ZjÖsrbx<|¥Dx‚sªtþw¥n•tk§j£fäoÂimfä]|.~ËuÅv*’^lzhUaí]znïkCgòmõ[@epr}`dl„i je…ixdŸnsÛxŸyvŽ€«ŠÔ‘‚‘1uu0tÕov>yIÿ€H‹ë‹Ã“Г%‹i’™œT¢Ð­ ˜uŸ~žÊ“»¢»²Óºé¶&Ÿÿ›– x—àšœ—I™Ý– ›å˜ÏœÂ¡r®$µÁžâ°™¹‚¯ž}¿ŠÀ9œjŸw¿ÂÀ²ŒÂÄ¿­ÄgʀÉÍåÐyÝ+èß Ç#Å¿?À§¶:ª¡+–F«ô¬ªnŠš Ü¢9ŸBŸV§‰¶&œ_’ȂË Ëݝb™f–Œ“X€¶uœKĚ¿­‹‘„í{—ņ¯“íŒk”l[l b=b¢b—`Iešu¹‘w¥‹‘ Ÿ­QÀÇŠËÊ/}w~q|ë}©|áy"têtô€€Q}‚€H„§Š †Š‚Ÿƒ…oÐŒO’Á’­œß¶ˆ!‰‡ •‡›šž–Z– —T¿œ”GŽÙQŽäËŸ°Š^¥F¡^Š©#®¹¢§¬Œ¹Üžºž×ÂõÐпÑÿŽ·oµÕŽFŒ¶Çi®K€$š`™Ô¡­€Í€Ø¡J’€*€>vµž¿¯–·¡·µjýgÞhœ]Þgè`ßh¯h¯k÷r}qÓ[,RHDi(yó{[€Ê|U…>8†s‡©{wâyz§}ȉƆ8|Ήa•8‘³”p“²‰ž*¢X£p¢lšÔ©Uš)š¡«ý²Þš§»«+¯–¡ê¡…Ÿ×£¡ŸKžŽªú²µg®K³›Ž °JÀ“ǺÅuÒFÏøÙCâ ß>œ¹¶u¹;ÃÒÍ Ù/Ôä×ZšÀ§&¡Ë¡­Ÿ×œ6‰‰…>zMyàx(r-uÚ{[vµšzC~ê„Š|KyÖrÃiÒ†~¶ ð?r7nŽm¥`ÂnŸu:tJrjeY8Q™N `®W”]«O.NèPOKL€VaÙkjSb ]ûj,bÊaXVþWø]èn1t€l¡_Yd\}w“M“‰™ ©Uµ^¹Ñ¹n™ ›wŸ™=¢Ù¢‘Ÿ•L­HÄ5ѹ׌ÓÕ~?r×güZYhœlÞk&Y}b)[­X3Cbgy_Èdúl `Âw¥b\WNXoX\PŸa9^õV?S¡TºQ"FÑ8†Xò\Qb—G€RvVL­JœPS—Wu[]NŽR&Xèe…o…fDjše_Žr‡u{t…|Ks‹€Þv«÷€Ó{Ô„„Dý$Ž%’…“ø‘Ü“šˆœq™ƒ–æèŽ9ŽÐ‹KŽ0$‘m®‡;ŠQ°“„†-…òƒ6‚Ÿ„‚Ü‘“lˆš‡¡…³-ÁûÈcɚ{*}1vytš}‹‚'y@o|ƒ^Š ‚x„9€„„§|jzŠ„0ƒ{‡ ‰ã•Ä—ýšBŸÄ°}(q¬tšv>mlñlffkpÆxOztË‚ÜiÇaC[šRÐ_dXebÊtvszK…Šµ†v~·‚m†`ƒ^y–ú¢©×v*mˆlÊmnŸplmo™egiùj|bh8a&Là]µtTtÁsZnŸ{~ê}ZmÎjÖnniŒj"jÖgÞpíjo?nÛp%tgt+ic[@[ N>_njÌn eovepÏy]r7y­qÓkMv„oój|…R“»˜Xšƒ§Ú§ã©Ub)gRm$cöj]xŸsðyÌ€p|›}<nOnÛlj@tšr7t@mõqi2s<lÔtJn1iðxÒ‡ïÓ™À•mºq\e^cjy6u±y†fkiÜeÕej­hØh_plx<rsmxÜ„X‰÷ÍuX€ „Ùƒ€{À|õw¥‰u‰aŒ©ŽWŽš“—rŒ ‡;‡Ÿ„wâŽÅ›åš4®Ž•€«ƒJsðoé‰a…À*l«sð|U{€¶~|zãyý_‹–FžÓ£ÊsŽuv˜x(wBp9smlrwˆwõvonŸxï}È|.~£~™k}1{G|†¯{—|›ˆTŽ|…“ŠNØ™R›™Ô€›¶uŒ«œ¹ÅŸ7šÃŽ”›ú¡Ë€8š. ùŸ×šU ªãž\€8¥Û¢ E¬Å»ÐŒ)Ã;ƃŞÆzÈæÎhÊ/¢Š xîžÓ ª£>¢Ù£p£f¢²›Ü¥;®K²òžiÁ¿ÄSÌ}Éý×úÙÆÝJÀŒºq·˜»k¹w»ã³s²Êªœª(¶¹œ¹OÁ¥2šµž¿³AŧпÙWä˜åLæx—®Q„ž‚Ü’­uDvy,zão^iukwit{n;u»|7yr|.n ^â\Xeb mÄv4og[XRb†›–•™è™Ô€Ø°+ŒQŒ˜u•õŽk‚ —§Ïª1¬Œ­p„0‹Uœ€«—›n¡€£ÞsPuît…o^pšpmël m‘röjÁrìs–oþtrjpãu%y|ukvµrjIš…3ŠQˆm¥m`kŠfînïp‰p/orqçnŸ[ýxùxF{Ôt®rsp²rÍuørLtôkWs1~ꀍtvvò~+€ÊŒz$—g£>•s“l•-•~“X•-šB•U˜‰šL›nš}§”§Æ§:¯‹ŸÈ׎Ç8©ìª‹¥m­­Ý²Rº£ŸwŸŸ÷¢»Ÿë™z®Vœ°Í<º›åže™H—{Ÿj ‹¢M Yš‘¢™è˜l¬ŽÒÀv‡ÇA“Ћt…oŠè„ø„&†ŠŠ Žv‚³{4¿‘³”û•ØŒ(ˆ„“Žšƒ{ƒ…‚Ÿœ™R™ œé›F›È”3¢ø£*¢a§ã€A¢ž«£›O®Ä»Ÿ‹ËԻſž’¿ÀbÆÀŲÅÆƃÊNÊbέÍwÕ¡ÒxæZËÝÊÀv¿^ÓþáðåØíW쀲R¥€Ÿ$kv˜šŸ×¡"£pŸ7šŠªZŽÛµ^žâµàµ^šŠèˆš†iŽ‚³€„{Q~zÐ…˜{—„a‡Z„u€Q‡ „&…R†ì‹º‹âŽî‰—Ì¡gš¬ Š—°ŽÅŠ—ž*®V¶²œ¿ß†Š„0xmtàˆ5‹7‘1Qsðx³€z€vzWÍ‚ }{=y|xF~|sÛpÆ{xæVr}o£lŽ}ðƒÁ‡c‹7‰ŒŠµ”‹Ã-‡m‰²‰N‘Ÿ¶„lƒÖƒr{À•sÄ‘džđŸ—5™ •s“í–Ò›‹¢M” “l“’€“øyŸÄ§§¡J›±9ŒƒÄJÊÁe¡€§Ú¢Š¡Ö¢l£µ¡ °ži»Ð¹Ž±Œ«š¶Â~’ÄóÍPĚû/²¶È©чÔMۜÞb¶žµ^²ž’±a°©.¬kª‹«"¬Å©×¥Ò®B©t®B©L£¡¢X¬ÅŽd¹O¿€·ƒ› ™”À¿–Û ³€áª©¡6ˆrƒ!Bö~ô€¶„0…3‰Ú‹Uƒ€~]zWpNfXvèwBzípušt{o…~™}œ¹vÉws|`€Qx2âƒê%}ðww섲tqqÓg¢x³x2vû{fy†|›sPz÷~ŽÍ‘£òº]ÆûÈœÐ3—šž¢˜u—£šµŸÊÍPÓJ•õ“v’Š¬“’!”‡Ò™f¡™¡r€L Ÿ P™ûŠr³_º®¶®œ­Ê¬îš4®öÃPÒÒàáæïâþçÕî>ñ™çèîëêöìªïÑͯÜÙ÷g¢¬Àk©·G~ߟ.¥Ç¢M๞Ó²†`ŒšU¶Ïy"ß¿‡Ÿ¥ŸŸŸ„“|jº}c‰Wû,v¿Kœ– Õz™4 ¢ž§ÇÕGÑá…£µ€j§ã¯E˜¹1mUŸn·¡z&ˆ¬šŠ)ጌ_Ä,€¶Ž÷ã²ÓO¹ŸnJL–xtgœ_d¬:¯‹”>kŠÝ²¿XŽ”¬O$ZÍY‘P±®â¡õx­bÊ ¶±Œgüµ!­pµ5I)ŠÁµÂì—{ ÇºhŸ(ÔaE‡µ5ŸYžAáҟ˘XµôŽ»Nž«ÏЯPo̬Åÿå›ÞkžH˜Ԟ±9{•‡LÃY²„3ë¡Ëübë– ˆÔa‰”pb}‹ËeŽï0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€¢€¡€£€0€ €0€ €B@¡€ljO¢€v'^=ࡀ0€ €B@¡€lÚ\¢€y¿É£€|‹:¢€0€ €B@¡€lÓ¢€v<£€^<•£€0€ €B@¡€lŽà¢€yÓᣀ|‰ï€€0€ €B@¡€–¢€Û£€ˆ(X¥€0€ €B@¡€Œ¢€#rᣀŠu²Š€0€ €B@¡€K¢€ï£€ˆ' §€0€ €B@¡€»¢€#†ù£€Štg0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€¢€#¡€£€0€ €0€ €B@¡€Zð¢€/†e£€œã…¡€0€ €B@¡€= ˜¢€5Y­£€šýù¢€0€ €B@¡€Zæ'¢€/k2£€,£€0€ €B@¡€=±¢€5>z£€›FŠ€€0€ €B@¡€ƒ¢¢€x-£€ü`Õ¥€0€ €B@¡€eŒ¢€%Ku£€ú{IŠ€0€ €B@¡€ƒ˜¢€\ú£€ü©f§€0€ €B@¡€e²©¢€%0B£€úÃÚ0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€$¢€(¡€£€0€ €0€ €B@¡€…¢€J£€ÿüÏ¡€0€ €B@¡€ Š¢€ûD£€ñgÜ¢€0€ €B@¡€é9¢€}û£€>“£€0€ €B@¡€ àZ¢€ûõ£€ñ© €€0€ €B@¡€Žm¢€wý£€Ù€0€ €B@¡€€ Ž¢€bŒ£€ËY¬Š€0€ €B@¡€³ì!¢€wîs£€Ú0c§€0€ €B@¡€£ãB¢€brm£€˛p0€ €¡€0€€€helix¢€ €¡€0€ €¡€¡€0€0€ €¡€0¢€<¡€¢€0€ €0€ €B@¡€ªH¢€àj£€9è8¡€0€ €B@¡€3ü˜¢€ÍJ°£€K¯¢€0€ €¡€0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€C¢€G¡€£€0€ €0€ €B@¡€ÿMQô¢€/4€£€˜hÞ¡€0€ €B@¡€ÿWÊ4¢€5€×£€ÿ|z¢€0€ €B@¡€ÿM Í¢€/'Ø£€˜K@£€0€ €B@¡€ÿWƒ ¢€5˜ £€ÿ|\c€€0€ €B@¡€ÿžŒ¢€îÃŽ£€³nÖ¥€0€ €B@¡€ÿ*ü¢€õ3磀—ùŠ€0€ €B@¡€ÿW•¢€î¶è£€³Q8§€0€ €B@¡€ÿ)ÏÕ¢€õ'£€—b[0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€_¢€c¡€£€0€ €0€ €B@¡€ÿì.¢€Ò£€ÿ6?B¡€0€ €B@¡€ÿ™¢€às©£€ÿQ_¢€0€ €B@¡€ÿ³¢€ÑØ£€ÿ6Ub£€0€ €B@¡€ÿ׃¢€àC"£€ÿQ*€€0€ €B@¡€ã†¢€Yœm£€€ú¥€0€ €B@¡€œñ¢€h‰£€šÛŠ€0€ €B@¡€ªp¢€Yk检€§€0€ €B@¡€›ÎÛ¢€g×£€šñ70€ €¡€0€€€helix¢€ €¡€0€ €¡€¡€0€0€ €¡€d¢€k¡€¢€0€ €0€ €B@¡€2bp¢€Ì=(£€±¡€¡€0€ €B@¡€¶¢€uKX£€„!¢€0€ €¡€0€ € ¡€0€€€helix¢€ €¡€0€ €¡€¡€0€0€ €¡€p¢€z¡€¢€0€ €0€ €B@¡€ÿIߢ€ž^ø£€4°H¡€0€ €B@¡€Ôµø¢€)2£€ºìh¢€0€ €¡€0€ € ¡€0€€€helix¢€ €¡€0€ €¡€¡€0€0€ €¡€~¢€Œ¡€¢€0€ €0€ €B@¡€Pß ¢€o% £€Åð¡€0€ €B@¡€ÿZË¢€ýœ£€}:˜¢€0€ €¡€0€ € ¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€¢€“¡€£€0€ €0€ €B@¡€†ÄŠ¢€ñ×M£€ìq¡€0€ €B@¡€•#a¢€³£€4Ö¢€0€ €B@¡€†Óñ€-£€³i£€0€ €B@¡€•2Å¢€⣀û΀€0€ €B@¡€þ׫¢€#ý£€ÉèÁ¥€0€ €B@¡€ 6¢€-ÿ²£€º1&Š€0€ €B@¡€þ碀ðÝ£€ɯ¹§€0€ €B@¡€ E墀-̒£€¹ø0€ € ¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€ž¢€¢¡€£€0€ €0€ €B@¡€+S ¢€O I£€Ï«t¡€0€ €B@¡€2A¬¢€bðr£€¹•¢€0€ €B@¡€+n³¢€O? £€Ïàò£€0€ €B@¡€2]V¢€c"6£€¹Ë€€0€ €B@¡€îÙ¹¢€öJ¡£€œt¥€0€ €B@¡€õÈ\¢€ -Ê£€§Š€0€ €B@¡€îõc¢€ö|e£€œRò§€0€ €B@¡€õ䢀 _Ž£€§=0€ € ¡€0€€€helix¢€ €¡€0€ €¡€¡€0€0€ €¡€£¢€®¡€¢€0€ €0€ €B@¡€{¢€xð£€NÓ°¡€0€ €B@¡€Õ¯ ¢€ÞqP£€¹Þ¢€0€ €¡€0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€º¢€¿¡€£€0€ €0€ €B@¡€‘šÂ¢€m\£€ÿ=N顀0€ €B@¡€ž‹L¢€†Ÿv£€ÿ3m¢€0€ €B@¡€‘Ÿã¢€lðY£€ÿ=d£€0€ €B@¡€žm¢€†Ÿs£€ÿ2Ñ耀0€ €B@¡€°žs¢€È;4£€ÿ€é¥€0€ €B@¡€œšý¢€áêN£€þûomŠ€0€ €B@¡€°œ”¢€È1£€ÿ]d§€0€ €B@¡€œ®¢€áËK£€þû'è0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€À¢€Å¡€£€0€ €0€ €B@¡€ۖ+¢€ÇúX£€þŒ{0¡€0€ €B@¡€ß a¢€æ¶£€þžc^¢€0€ €B@¡€Ûb ¢€È £€þŒ³Ó£€0€ €B@¡€ÞÕV¢€æg£€þžœ€€0€ €B@¡€æš¢€ÉÃ`£€ÿ_ã8¥€0€ €B@¡€‘YТ€çΟ£€ÿ[ËfŠ€0€ €B@¡€²¢€ÉÑ£€ÿ`Û§€0€ €B@¡€‘%Å¢€çÜo£€ÿ\ 0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€Т€Ù¡€£€0€ €0€ €B@¡€y¢€6ÉÓ£€šÚ¡€0€ €B@¡€ÿë1¢€-Ö£€”Ýw¢€0€ €B@¡€tŸ¢€6šz£€› Š£€0€ €B@¡€ÿæÝ¢€-ŽŒ£€•#û€€0€ €B@¡€\¢€‘%Ë£€5üÝ¥€0€ €B@¡€rÎ1¢€ˆ2 £€0NŠ€0€ €B@¡€WŸ¢€‘r£€6Ca§€0€ €B@¡€rÉÝ¢€ˆŽ£€0FÒ0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€Ý¢€础£€0€ €0€ €B@¡€Î0K¢€‘J£€ Ú¡€0€ €B@¡€œª¢€Œ·Ø£€ùD¢€0€ €B@¡€Îl%¢€‘`§£€ ¬û£€0€ €B@¡€œY„¢€ŒÍ⣀Ì%€€0€ €B@¡€iÀƒ¢€¿„V£€ ·ò¥€0€ €B@¡€X­â¢€ºñ‘£€ò׊€0€ €B@¡€iü]¢€¿š`£€ ŠÓ§€0€ €B@¡€X錢€»›£€ò©þ0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€袀󡀣€0€ €0€ €B@¡€;ZŠ¢€ŽLü£€-Ña¡€0€ €B@¡€>¢€³ñ7£€L7³¢€0€ €B@¡€;š@¢€ŽS £€-ʬ£€0€ €B@¡€>P¢€³÷E£€L0þ€€0€ €B@¡€Év¢€Ÿè‹£€6噥€0€ €B@¡€qO¢€ŸŒÆ£€UK멀0€ €B@¡€¢€Ÿî™£€6Þ䧀0€ €B@¡€Ÿé¢€Ÿ’Ô£€UE60€ €¡€0€€€helix¢€ €¡€0€ €¡€¡€0€0€ €¡€ú¢€¡€¢€0€ €0€ €B@¡€âüˆ¢€2h£€G.š¡€0€ €B@¡€brH¢€`£€æ0¢€0€ €¡€0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€¢€ ¡€£€0€ €0€ €B@¡€¿ÅB¢€(þS£€nÒ0€ €B@¡€ŒŒ,¢€Æ_£€Qä ¢€0€ €B@¡€Àƒ¢€(ã0£€nÓ㣀0€ €B@¡€œm¢€«<£€Q倀0€ €B@¡€qÒ¢€ÿXw„£€¹xN¥€0€ €B@¡€n„Œ¢€ÿO?£€œ‰lŠ€0€ €B@¡€q×¢€ÿX\a£€¹yC§€0€ €B@¡€nÍý¢€ÿO$m£€œŠa0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€¢€¡€£€0€ €0€ €B@¡€fûÀ¢€þÆî~£€Ý¡€0€ €B@¡€‚¹±¢€þËÿ£€Èꢀ0€ €B@¡€fáN¢€þÇ/B£€A¥£€0€ €B@¡€‚Ÿ?¢€þÌ?Ó£€ë²€€0€ €B@¡€,Á€¢€þFðÞ£€È.¥€0€ €B@¡€Hq¢€þLo£€ÓؚŠ€0€ €B@¡€,§¢€þG1¢£€ÈQU§€0€ €B@¡€Hdÿ¢€þLB3£€Óûb0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€¢€#¡€£€0€ €0€ €B@¡€%¢€þ9šŸ¡€0€ €B@¡€5\΢€þT£€€[Ý¢€0€ €B@¡€¡¢€þ£€š^"£€0€ €B@¡€5ST¢€þÕó£€€뀀0€ €B@¡€œÓ¢€þ춎£€!+L¥€0€ €B@¡€#Ԇ¢€þì|ô£€èŠ€0€ €B@¡€“Y¢€þìŒ-£€ êZ§€0€ €B@¡€#Ë ¢€þìR“£€§#0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€(¢€-¡€£€0€ €0€ €B@¡€.å6¢€ ¯£€ãA¹¡€0€ €B@¡€0+¡¢€‚Xf£€ÆŽÝ¢€0€ €B@¡€.³Ÿ¢€D‹£€ã*’£€0€ €B@¡€/ú)¢€‚B£€Ɲ¶€€0€ €B@¡€ï™>¢€#Ö>£€³T1¥€0€ €B@¡€ðß©¢€!õ£€–ÇUŠ€0€ €B@¡€ïgÆ¢€$£€³= §€0€ €B@¡€ð®1¢€YÑ£€–°.0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€4¢€;¡€£€0€ €0€ €B@¡€ûyk¢€ÿqz£€Üq”¡€0€ €B@¡€³ê¢€ÿY鑣€Þô0€ €B@¡€ûšõ¢€ÿq¥€£€ܝÁ£€0€ €B@¡€ãt¢€ÿZ£€ß!€€0€ €B@¡€PƒË¢€ÿü£€ÿ>䥀0€ €B@¡€cŸJ¢€þíl!£€Â>Š€0€ €B@¡€P³U¢€ÿ(£€ÿk§€0€ €B@¡€cíÔ¢€þ헡£€îk0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€B¢€F¡€£€0€ €0€ €B@¡€r¿¢€þf Ú£€ÐüÞ¡€0€ €B@¡€¯Þ¢€þvtœ£€âõ¢€0€ €B@¡€°¢€þeô„£€ÐÓœ£€0€ €B@¡€°ࢀþv\g£€âËñ€€0€ €B@¡€‹B¢€þõ)’£€`ù¥€0€ €B@¡€­Ò¢€ÿ‘u£€rñJŠ€0€ €B@¡€‹€M¢€þõ<£€`Ïõ§€0€ €B@¡€ë ¢€ÿy£€rÈ)0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€G¢€Q¡€£€0€ €0€ €B@¡€ÇãТ€þ÷'M£€»5¡€0€ €B@¡€Øžž¢€þÝÆQ£€œ⢀0€ €B@¡€ÇТ€þ÷€£€ºÍý£€0€ €B@¡€Ø€ÿ¢€þݳ„£€ŒÉª€€0€ €B@¡€2ÂX¢€ۗţ€°%¥€0€ €B@¡€C—@¢€Â6É£€ «ÒŠ€0€ €B@¡€2®Ÿ¢€ۄø£€fí§€0€ €B@¡€Cƒ‡¢€Â#ü£€ bš0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€R¢€V¡€£€0€ €0€ €B@¡€;Ka¢€µ—j£€b“:¡€0€ €B@¡€2`i¢€º­£€P]¢€0€ €B@¡€;Yö¢€µã€£€bŠB£€0€ €B@¡€2nþ¢€ºù×£€Ge€€0€ €B@¡€“A¢€Ïª£€)×Ê¥€0€ €B@¡€ŠI¢€Ô0Ý£€F”튀0€ €B@¡€“Ö¢€Ïf䣀)ÎÒ§€0€ €B@¡€Š(Þ¢€Ô}£€F‹õ0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€W¢€\¡€£€0€ €0€ €B@¡€c‘n¢€€ÄP£€l@8¡€0€ €B@¡€]5¢€€F£€Np¶¢€0€ €B@¡€cÒꢀ€›Û£€l2Ù£€0€ €B@¡€]S±¢€£ñÑ£€NcW€€0€ €B@¡€æ•V¢€þÏä8£€Œ;ž¥€0€ €B@¡€à¢€þÏ:.£€nl6Š€0€ €B@¡€æÖÒ¢€þϻ「.Y§€0€ €B@¡€àW™¢€þϹ£€n^×0€ €¡€0€€€strand¢€ €¡€0€ €¡€¡€0€0€ €¡€]¢€a¡€£€0€ €0€ €B@¡€ÂòÚ¢€þÌ«ª£€:â顀0€ €B@¡€ÃyÌ¢€þ¶“‡£€%×k¢€0€ €B@¡€Ã=£¢€þ̝ £€:ô$£€0€ €B@¡€Ãĕ¢€þ¶„磀%芀€0€ €B@¡€ŠÀ"¢€þKuŠ£€Á"¥€0€ €B@¡€‹G¢€þ5]g£€¬›Š€0€ €B@¡€‹ 뢀þKfꣀÁ3T§€0€ €B@¡€‹‘Ý¢€þ5NÇ£€¬'Ö¡€1€¡€0€£€  Š€1€Ž€0€ €¡€0€ €С€ ¢€ ¡€ Hydrolase¢€0€gCrystal Structure Of A Deacylation-Defective Mutant Of Penicillin-Binding Protein 5 At 2.3 A Resolution£€0€‚Mol_id: 1; Organism_scientific: Escherichia Coli; Organism_taxid: 562; Cellular_location: Periplasm; Gene: Daca; Expression_system: Escherichia Coli; Expression_system_taxid: 562; Expression_system_strain: Mc1061; Expression_system_plasmid: Pbr322; Expression_system_gene: Daca§€0€ €0€ €1€«€È¡€1€¶€0€¢€0€ €Escherichia coli£€1€0€ €taxon¡€ €2€€1€Enterococcus coli7"Bacterium coli" (Migula 1895) Lehmann and Neumann 1896Bacterium coli"Bacillus coli" Migula 1895 Bacillus coli'"Bacterium coli commune" Escherich 1885Bacterium coli commune;Escherichia coli (Migula 1895) Castellani and Chalmers 1919¥€0€ € €0€ € Escherichia¡€coli£€aBacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia€€ Š€BCT¢€0€ € ¡€ ¢€kŠ€§€A‚kDDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRDINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGREAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRMKDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFGDPVID¢€0€ €0€¡€0€ € ¡€ ¢€ £€0€ €'¡€ˆ¢€ˆ£€ˆ€€'¢€0€ € ¡€ ¢€ £€0€ €'¡€ˆ¢€ˆ£€ˆ€€'£€0€ €¡€ ¢€ £€0€ €'¡€ˆ¢€ˆ£€ˆ€€'€€0€ €¡€ ¢€ £€0€ €'¡€ˆ¢€ˆ£€ˆ€€'¥€0€ €¡€ ¢€ £€0€ €'¡€ˆ¢€ˆ£€ˆ€€'Š€0€ €¡€ ¢€ £€0€ €'¡€ˆ¢€ˆ£€ˆ€€'§€0€ €¡€ ¢€ £€0€ €'¡€#(¢€#(£€'€€'š€0€ €¡€ ¢€ £€0€ €'¡€ˆ¢€ˆ£€ˆ€€'©€0€ €¡€ ¢€ £€0€ €'¡€ˆ¢€ˆ£€ˆ€€'ª€«€0€ €'¡€$T¢€|£€ô€€'¬€­€0€ €ÿ¡€¢€£€€€'®€'¯€'°€ ±€в€г€ žŽ€FPµ€N ¶€ˆ·€0€ €¡€ ¢€ £€€€ž€0€ €¡€ ¢€ £€€€¹€