|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
683-1078 |
1.12e-43 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 165.08 E-value: 1.12e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 683 RSARRLLPAELQDGAGPGIAINSISISSTLCATGSADGYLRLWPLDFSAVVLEAEHEAPVSSVCISPDGHKVLCTTTARS 762
Cdd:COG2319 22 AAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGT 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 763 LGYLDIQSRGYSTLMRSHEDSI--LAFSVDGvwKQMATVSRDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHPTQRILAC 840
Cdd:COG2319 102 VRLWDLATGLLLRTLTGHTGAVrsVAFSPDG--KTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLAS 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 841 GFDSGVVRTFSLTASDLLTEHKQHRTRIAGLTFSPDGNFMFSSCLQGTLALYScvAQKSQVLRVLgnvvaRDAGSGPDAL 920
Cdd:COG2319 180 GSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWD--LATGKLLRTL-----TGHSGSVRSV 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 921 VLSGDSRLLAFVGPSKYVvtvmeacsldELLRVDISILDLNSTALDSAVR-ICFAPvsRGELLVSTSS-NRILVLDAKTG 998
Cdd:COG2319 253 AFSPDGRLLASGSADGTV----------RLWDLATGELLRTLTGHSGGVNsVAFSP--DGKLLASGSDdGTVRLWDLATG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 999 RLVREVSPvHKLSCSSLALSKDARYLLTAG-DKVIKVWDYRMRFDInfQVYIGHSEPVYQVAFTPDQQHVISVGD--AIF 1075
Cdd:COG2319 321 KLLRTLTG-HTGAVRSVAFSPDGKTLASGSdDGTVRLWDLATGELL--RTLTGHTGAVTSVAFSPDGRTLASGSAdgTVR 397
|
...
gi 2024356826 1076 LWD 1078
Cdd:COG2319 398 LWD 400
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
1293-1699 |
2.87e-41 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 158.15 E-value: 2.87e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1293 WLGHVEEISTLAVSHDAQALASASGKRdgdshcQICIWNTQDGICTARLFHHKTQVQAMAYSRDDRFLATVGDynDQTLA 1372
Cdd:COG2319 74 LLGHTAAVLSVAFSPDGRLLASASADG------TVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSA--DGTVR 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1373 LWSTYTYELLSS-TRISEPVHDVAFSPfshremacvgkgaimfwlleqhgadinlkvhrapvpevlgpveltslcygaD- 1450
Cdd:COG2319 146 LWDLATGKLLRTlTGHSGAVTSVAFSP---------------------------------------------------Dg 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1451 TLLYSGTNSGQVCVWDTETNSCFMTWEADEGEIGMLVC--RCNRLVSGSNTKRIRLWAVGAMQELR-LKGPKGRPSSVll 1527
Cdd:COG2319 175 KLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFspDGKLLASGSADGTVRLWDLATGKLLRtLTGHSGSVRSV-- 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1528 ehEITLDGTIVSMAFDDslemgivgttaGTLWYINWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWSLGR 1607
Cdd:COG2319 253 --AFSPDGRLLASGSAD-----------GTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLAT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1608 MELVVQFQVLNQSCHCLAWKPHpsfsweaeSQHVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGG 1687
Cdd:COG2319 320 GKLLRTLTGHTGAVRSVAFSPD--------GKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGS 391
|
410
....*....|..
gi 2024356826 1688 KDGMVAVSSPRT 1699
Cdd:COG2319 392 ADGTVRLWDLAT 403
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
480-893 |
1.14e-38 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 150.45 E-value: 1.14e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 480 AVIVTLQIQTGEQRFFTGHTDKVSALAFNGSSTLLASAqeGPLGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLC 559
Cdd:COG2319 59 TLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASA--SADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLA 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 560 GVGKDGhgktMVVVWNTAQvthgGEVLVLARAHTDvDIQTLKIASfDDTRMVSCGRD-SVRLWRVRNGvlrSCPVNLGEy 638
Cdd:COG2319 137 SGSADG----TVRLWDLAT----GKLLRTLTGHSG-AVTSVAFSP-DGKLLASGSDDgTVRLWDLATG---KLLRTLTG- 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 639 HALEFTDLAFeeghSaarePDDRTLficsrsghvlevdyknvcvrsarrllpaelqdgagpgiainsisisstlcATGSA 718
Cdd:COG2319 203 HTGAVRSVAF----S----PDGKLL--------------------------------------------------ASGSA 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 719 DGYLRLWPLDFSAVVLE-AEHEAPVSSVCISPDGHKVLCTTTARSLGYLDIQSRGYSTLMRSHEDSI--LAFSVDGvwKQ 795
Cdd:COG2319 225 DGTVRLWDLATGKLLRTlTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVnsVAFSPDG--KL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 796 MATVSRDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHPTQRILACGFDSGVVRTFSLTASDLLTEHKQHRTRIAGLTFSP 875
Cdd:COG2319 303 LASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSP 382
|
410
....*....|....*...
gi 2024356826 876 DGNFMFSSCLQGTLALYS 893
Cdd:COG2319 383 DGRTLASGSADGTVRLWD 400
|
|
| CFA20_dom |
pfam05018 |
CFA20 domain; This domain is characteriztic of cilia- and flagella-associated protein 20 ... |
4-194 |
1.24e-38 |
|
CFA20 domain; This domain is characteriztic of cilia- and flagella-associated protein 20 (CFA20). CFA20 is a cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. In Chlamydomonas reinhardtii, it stabilizes outer doublet microtubules (DMTs) of the axoneme and may work as a scaffold for intratubular proteins, such as tektin and PACRG, to produce the beak structures in DMT1. Other proteins contain a domain with homology to CFA20. WDR90/POC16 contains such a domain in its N terminus, followed by a large C-terminal domain with multiple WD40 repeats. This domain is also present in the N terminus of uncharacterized protein C3orf67.
Pssm-ID: 461521 Cd Length: 185 Bit Score: 143.11 E-value: 1.24e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 4 AWQSPYLNVFKHFRV---EEWKRSHKEGDVTTVMDKTLKGTVYRIRGSIPASNYLQLPRTGSQSLGLCGRYLYLLFRPLp 80
Cdd:pfam05018 5 TFQSGFLSIFYSIGSkplQIWSKKVKNGHIKRVTDDDIKSNVLEIVGTNVATTYITCPADPKQSLGIKLPFLVLLVKNL- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 81 RKYFVVHLDVATEENQVVRVSFSNLFKEFKSTATWLQFPFicgaakgslhdgkarasrrelvgaaPADTRWTCLVLDLHY 160
Cdd:pfam05018 84 GKYFSFEIQILDDKNVRRRFRFSNFQKVTKVKPFITTMPL-------------------------RLNEGWNQIQFNLAD 138
|
170 180 190
....*....|....*....|....*....|....
gi 2024356826 161 VLSLYLSRRYSHLKSIKLCSNLLVKNVCTSDLLF 194
Cdd:pfam05018 139 FTRRAYGTNYVETVRVQIHANCRLRRIYFSDRLY 172
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
1426-1748 |
3.84e-29 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 119.36 E-value: 3.84e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1426 LKVHRAPVpevlgpvelTSLCYGADT-LLYSGTNSGQVCVWDTETNSCFMTWEADEGEIGMLVCRC--NRLVSGSNTKRI 1502
Cdd:cd00200 5 LKGHTGGV---------TCVAFSPDGkLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASAdgTYLASGSSDKTI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1503 RLWAVGamqelrlkgpKGRPSSVLLEHEitldGTIVSMAFDDSLEMGIVGTTAGTLWYINWKESTSIRLISGHKSKVTEV 1582
Cdd:cd00200 76 RLWDLE----------TGECVRTLTGHT----SYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSV 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1583 SFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLNQSCHCLAWKPhpsfsweaESQHVVAGYSDGTIRVFSIsRTEMEL 1662
Cdd:cd00200 142 AFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSP--------DGEKLLSSSSDGTIKLWDL-STGKCL 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1663 K-MHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTGMTVRILADHKGSAITVlqctrkqyhdfGVEGGELWLAT-SS 1740
Cdd:cd00200 213 GtLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSL-----------AWSPDGKRLASgSA 281
|
....*...
gi 2024356826 1741 DRRVSVWA 1748
Cdd:cd00200 282 DGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
495-893 |
8.32e-27 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 112.43 E-value: 8.32e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 495 FTGHTDKVSALAFNGSSTLLASAqeGPLGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLCGVGKDGhgktMVVVW 574
Cdd:cd00200 5 LKGHTGGVTCVAFSPDGKLLATG--SGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDK----TIRLW 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 575 NtaqvTHGGEVLVLARAHTDvDIQTLKIAsfDDTRMV-SCGRD-SVRLWRVRNGVLRSCPvnlgeyhaleftdlafeEGH 652
Cdd:cd00200 79 D----LETGECVRTLTGHTS-YVSSVAFS--PDGRILsSSSRDkTIKVWDVETGKCLTTL-----------------RGH 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 653 SAarepddrtlficsrsghvlevDYKNVCVRSARRLLpaelqdgagpgiainsisisstlcATGSADGYLRLWplDFSAV 732
Cdd:cd00200 135 TD---------------------WVNSVAFSPDGTFV------------------------ASSSQDGTIKLW--DLRTG 167
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 733 VLEAE---HEAPVSSVCISPDGhkvlctttarslgyldiqsrgystlmrshedsilafsvdgvwKQMATVSRDNSIRVWD 809
Cdd:cd00200 168 KCVATltgHTGEVNSVAFSPDG------------------------------------------EKLLSSSSDGTIKLWD 205
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 810 LVSMQQLYDFTAAAEMPCAVSFHPTQRILACGFDSGVVRTFSLTASDLLTEHKQHRTRIAGLTFSPDGNFMFSSCLQGTL 889
Cdd:cd00200 206 LSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTI 285
|
....
gi 2024356826 890 ALYS 893
Cdd:cd00200 286 RIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
778-1078 |
4.13e-26 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 110.50 E-value: 4.13e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 778 RSHEDSI--LAFSVDGVWkqMATVSRDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHP-TQRILACGFDsGVVRTFSLTA 854
Cdd:cd00200 6 KGHTGGVtcVAFSPDGKL--LATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASAdGTYLASGSSD-KTIRLWDLET 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 855 SDLLTEHKQHRTRIAGLTFSPDGNFMFSSCLQGTLALYScvAQKSQVLRVLgnvvardagSGPDALVLSgdsrlLAFVGP 934
Cdd:cd00200 83 GECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWD--VETGKCLTTL---------RGHTDWVNS-----VAFSPD 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 935 SKYVVTvmeaCSLDELLRV-DISILDLNSTAL--DSAVR-ICFAPvSRGELLVSTSSNRILVLDAKTGRLVREVsPVHKL 1010
Cdd:cd00200 147 GTFVAS----SSQDGTIKLwDLRTGKCVATLTghTGEVNsVAFSP-DGEKLLSSSSDGTIKLWDLSTGKCLGTL-RGHEN 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024356826 1011 SCSSLALSKDaRYLLTAG--DKVIKVWDYRMRFDInfQVYIGHSEPVYQVAFTPDQQHVISVGD--AIFLWD 1078
Cdd:cd00200 221 GVNSVAFSPD-GYLLASGseDGTIRVWDLRTGECV--QTLSGHTNSVTSLAWSPDGKRLASGSAdgTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
1522-1887 |
1.09e-21 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 97.41 E-value: 1.09e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1522 PSSVLLEHEitldGTIVSMAFDDSLEMGIVGTTAGTL--WyiNWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGS 1599
Cdd:cd00200 1 LRRTLKGHT----GGVTCVAFSPDGKLLATGSGDGTIkvW--DLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1600 VRVWSLGRMELVVQFQVLNQSCHCLAWKPHPSFsweaesqhVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTD 1679
Cdd:cd00200 75 IRLWDLETGECVRTLTGHTSYVSSVAFSPDGRI--------LSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPD 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1680 GEMILSGGKDGMVAVSSPRTGMTVRILADHKGSaitVLQCTrkqYHDfgvEGGELwLATSSDRRVSVWasdwlkdkcell 1759
Cdd:cd00200 147 GTFVASSSQDGTIKLWDLRTGKCVATLTGHTGE---VNSVA---FSP---DGEKL-LSSSSDGTIKLW------------ 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1760 dwlsfpapaspeglgslppSLAAfcpwehGTLVYVGFGMQKealfyslrkkqvvekislpyFATSLSLSPAARFMAVGFS 1839
Cdd:cd00200 205 -------------------DLST------GKCLGTLRGHEN--------------------GVNSVAFSPDGYLLASGSE 239
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1840 ERLLRL-QRCPAGLPQDYAGHDDAVHLCRFAPAGRRLLTASH-SAVLVWE 1887
Cdd:cd00200 240 DGTIRVwDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSAdGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
1541-1888 |
2.48e-14 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 77.26 E-value: 2.48e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1541 AFDDSLEMGIVGTTAGTLWYINWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLNQS 1620
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1621 CHCLAWKPHPsfsweaesQHVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTG 1700
Cdd:COG2319 81 VLSVAFSPDG--------RLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1701 MTVRILADHKGSAITVlqctrkqyhDFGVEGgeLWLATSS-DRRVSVWasDWLKDKCelldwlsfpapaspegLGSLPps 1779
Cdd:COG2319 153 KLLRTLTGHSGAVTSV---------AFSPDG--KLLASGSdDGTVRLW--DLATGKL----------------LRTLT-- 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1780 laafcpwEHGTLVYvgfgmqkealfyslrkkqvvekislpyfatSLSLSPAARFMAVGFSERLLRLQRCPAG-LPQDYAG 1858
Cdd:COG2319 202 -------GHTGAVR------------------------------SVAFSPDGKLLASGSADGTVRLWDLATGkLLRTLTG 244
|
330 340 350
....*....|....*....|....*....|.
gi 2024356826 1859 HDDAVHLCRFAPAGRRLLTASHS-AVLVWEL 1888
Cdd:COG2319 245 HSGSVRSVAFSPDGRLLASGSADgTVRLWDL 275
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
1567-1604 |
1.59e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 49.23 E-value: 1.59e-07
10 20 30
....*....|....*....|....*....|....*...
gi 2024356826 1567 TSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWS 1604
Cdd:smart00320 3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
1566-1604 |
3.16e-07 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 48.11 E-value: 3.16e-07
10 20 30
....*....|....*....|....*....|....*....
gi 2024356826 1566 STSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWS 1604
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
1571-1795 |
5.32e-03 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 41.42 E-value: 5.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1571 LISGHKSKVTEVSFSP-DETLCATCGEDGSVRVWSLGRMEL-------VVQFQVLNQSCHCLAWkpHPSfsweAESQHVV 1642
Cdd:PTZ00421 70 ILLGQEGPIIDVAFNPfDPQKLFTASEDGTIMGWGIPEEGLtqnisdpIVHLQGHTKKVGIVSF--HPS----AMNVLAS 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1643 AGySDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTGMTVRILADHKGS-AITVLQCTR 1721
Cdd:PTZ00421 144 AG-ADMVVNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAkSQRCLWAKR 222
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024356826 1722 KqyhDFGVEGGelwLATSSDRRVSVWasdwlkdkcellDWLSFPAPASPEGLGSlppSLAAFCPW--EHGTLVYVG 1795
Cdd:PTZ00421 223 K---DLIITLG---CSKSQQRQIMLW------------DTRKMASPYSTVDLDQ---SSALFIPFfdEDTNLLYIG 277
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
497-564 |
6.10e-03 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 41.42 E-value: 6.10e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024356826 497 GHTDKVSALAFNGSST-LLASAqeGPLGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLCGVGKD 564
Cdd:PTZ00421 123 GHTKKVGIVSFHPSAMnVLASA--GADMVVNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKD 189
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
777-809 |
9.62e-03 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 35.75 E-value: 9.62e-03
10 20 30
....*....|....*....|....*....|...
gi 2024356826 777 MRSHEDSILAFSVDGVWKQMATVSRDNSIRVWD 809
Cdd:smart00320 8 LKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
683-1078 |
1.12e-43 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 165.08 E-value: 1.12e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 683 RSARRLLPAELQDGAGPGIAINSISISSTLCATGSADGYLRLWPLDFSAVVLEAEHEAPVSSVCISPDGHKVLCTTTARS 762
Cdd:COG2319 22 AAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGT 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 763 LGYLDIQSRGYSTLMRSHEDSI--LAFSVDGvwKQMATVSRDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHPTQRILAC 840
Cdd:COG2319 102 VRLWDLATGLLLRTLTGHTGAVrsVAFSPDG--KTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLAS 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 841 GFDSGVVRTFSLTASDLLTEHKQHRTRIAGLTFSPDGNFMFSSCLQGTLALYScvAQKSQVLRVLgnvvaRDAGSGPDAL 920
Cdd:COG2319 180 GSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWD--LATGKLLRTL-----TGHSGSVRSV 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 921 VLSGDSRLLAFVGPSKYVvtvmeacsldELLRVDISILDLNSTALDSAVR-ICFAPvsRGELLVSTSS-NRILVLDAKTG 998
Cdd:COG2319 253 AFSPDGRLLASGSADGTV----------RLWDLATGELLRTLTGHSGGVNsVAFSP--DGKLLASGSDdGTVRLWDLATG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 999 RLVREVSPvHKLSCSSLALSKDARYLLTAG-DKVIKVWDYRMRFDInfQVYIGHSEPVYQVAFTPDQQHVISVGD--AIF 1075
Cdd:COG2319 321 KLLRTLTG-HTGAVRSVAFSPDGKTLASGSdDGTVRLWDLATGELL--RTLTGHTGAVTSVAFSPDGRTLASGSAdgTVR 397
|
...
gi 2024356826 1076 LWD 1078
Cdd:COG2319 398 LWD 400
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
1293-1699 |
2.87e-41 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 158.15 E-value: 2.87e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1293 WLGHVEEISTLAVSHDAQALASASGKRdgdshcQICIWNTQDGICTARLFHHKTQVQAMAYSRDDRFLATVGDynDQTLA 1372
Cdd:COG2319 74 LLGHTAAVLSVAFSPDGRLLASASADG------TVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSA--DGTVR 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1373 LWSTYTYELLSS-TRISEPVHDVAFSPfshremacvgkgaimfwlleqhgadinlkvhrapvpevlgpveltslcygaD- 1450
Cdd:COG2319 146 LWDLATGKLLRTlTGHSGAVTSVAFSP---------------------------------------------------Dg 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1451 TLLYSGTNSGQVCVWDTETNSCFMTWEADEGEIGMLVC--RCNRLVSGSNTKRIRLWAVGAMQELR-LKGPKGRPSSVll 1527
Cdd:COG2319 175 KLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFspDGKLLASGSADGTVRLWDLATGKLLRtLTGHSGSVRSV-- 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1528 ehEITLDGTIVSMAFDDslemgivgttaGTLWYINWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWSLGR 1607
Cdd:COG2319 253 --AFSPDGRLLASGSAD-----------GTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLAT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1608 MELVVQFQVLNQSCHCLAWKPHpsfsweaeSQHVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGG 1687
Cdd:COG2319 320 GKLLRTLTGHTGAVRSVAFSPD--------GKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGS 391
|
410
....*....|..
gi 2024356826 1688 KDGMVAVSSPRT 1699
Cdd:COG2319 392 ADGTVRLWDLAT 403
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
1304-1747 |
7.83e-40 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 153.91 E-value: 7.83e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1304 AVSHDAQALASASGKRDGDshcqicIWNTQDGICTARLFHHKTQVQAMAYSRDDRFLATVGDyNDQTLALWSTYTYELLS 1383
Cdd:COG2319 1 ALSADGAALAAASADLALA------LLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAG-DLTLLLLDAAAGALLAT 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1384 STRISEPVHDVAFSPFSHREMACVGKGAIMFWLLEQHGADINLKVHRAPVpevlgpvelTSLCYGAD-TLLYSGTNSGQV 1462
Cdd:COG2319 74 LLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAV---------RSVAFSPDgKTLASGSADGTV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1463 CVWDTETNSCFMTWEADEGEIGMLVCRCN--RLVSGSNTKRIRLWAVGAMQELR-LKGPKGRPSSVllehEITLDG-TIV 1538
Cdd:COG2319 145 RLWDLATGKLLRTLTGHSGAVTSVAFSPDgkLLASGSDDGTVRLWDLATGKLLRtLTGHTGAVRSV----AFSPDGkLLA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1539 SMAFDDSLemgivgttagTLWyiNWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLN 1618
Cdd:COG2319 221 SGSADGTV----------RLW--DLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHS 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1619 QSCHCLAWKPhpsfsweaESQHVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPR 1698
Cdd:COG2319 289 GGVNSVAFSP--------DGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLA 360
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1699 TGMTVRILADHKGSAITVlqctrkqyhDFGVEGGelWLATSS-DRRVSVW 1747
Cdd:COG2319 361 TGELLRTLTGHTGAVTSV---------AFSPDGR--TLASGSaDGTVRLW 399
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
480-893 |
1.14e-38 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 150.45 E-value: 1.14e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 480 AVIVTLQIQTGEQRFFTGHTDKVSALAFNGSSTLLASAqeGPLGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLC 559
Cdd:COG2319 59 TLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASA--SADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLA 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 560 GVGKDGhgktMVVVWNTAQvthgGEVLVLARAHTDvDIQTLKIASfDDTRMVSCGRD-SVRLWRVRNGvlrSCPVNLGEy 638
Cdd:COG2319 137 SGSADG----TVRLWDLAT----GKLLRTLTGHSG-AVTSVAFSP-DGKLLASGSDDgTVRLWDLATG---KLLRTLTG- 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 639 HALEFTDLAFeeghSaarePDDRTLficsrsghvlevdyknvcvrsarrllpaelqdgagpgiainsisisstlcATGSA 718
Cdd:COG2319 203 HTGAVRSVAF----S----PDGKLL--------------------------------------------------ASGSA 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 719 DGYLRLWPLDFSAVVLE-AEHEAPVSSVCISPDGHKVLCTTTARSLGYLDIQSRGYSTLMRSHEDSI--LAFSVDGvwKQ 795
Cdd:COG2319 225 DGTVRLWDLATGKLLRTlTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVnsVAFSPDG--KL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 796 MATVSRDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHPTQRILACGFDSGVVRTFSLTASDLLTEHKQHRTRIAGLTFSP 875
Cdd:COG2319 303 LASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSP 382
|
410
....*....|....*...
gi 2024356826 876 DGNFMFSSCLQGTLALYS 893
Cdd:COG2319 383 DGRTLASGSADGTVRLWD 400
|
|
| CFA20_dom |
pfam05018 |
CFA20 domain; This domain is characteriztic of cilia- and flagella-associated protein 20 ... |
4-194 |
1.24e-38 |
|
CFA20 domain; This domain is characteriztic of cilia- and flagella-associated protein 20 (CFA20). CFA20 is a cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. In Chlamydomonas reinhardtii, it stabilizes outer doublet microtubules (DMTs) of the axoneme and may work as a scaffold for intratubular proteins, such as tektin and PACRG, to produce the beak structures in DMT1. Other proteins contain a domain with homology to CFA20. WDR90/POC16 contains such a domain in its N terminus, followed by a large C-terminal domain with multiple WD40 repeats. This domain is also present in the N terminus of uncharacterized protein C3orf67.
Pssm-ID: 461521 Cd Length: 185 Bit Score: 143.11 E-value: 1.24e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 4 AWQSPYLNVFKHFRV---EEWKRSHKEGDVTTVMDKTLKGTVYRIRGSIPASNYLQLPRTGSQSLGLCGRYLYLLFRPLp 80
Cdd:pfam05018 5 TFQSGFLSIFYSIGSkplQIWSKKVKNGHIKRVTDDDIKSNVLEIVGTNVATTYITCPADPKQSLGIKLPFLVLLVKNL- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 81 RKYFVVHLDVATEENQVVRVSFSNLFKEFKSTATWLQFPFicgaakgslhdgkarasrrelvgaaPADTRWTCLVLDLHY 160
Cdd:pfam05018 84 GKYFSFEIQILDDKNVRRRFRFSNFQKVTKVKPFITTMPL-------------------------RLNEGWNQIQFNLAD 138
|
170 180 190
....*....|....*....|....*....|....
gi 2024356826 161 VLSLYLSRRYSHLKSIKLCSNLLVKNVCTSDLLF 194
Cdd:pfam05018 139 FTRRAYGTNYVETVRVQIHANCRLRRIYFSDRLY 172
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
1284-1605 |
4.94e-36 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 142.74 E-value: 4.94e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1284 DLHSGSQNHWL-GHVEEISTLAVSHDAQALASASgkRDGdshcQICIWNTQDGICTARLFHHKTQVQAMAYSRDDRFLAT 1362
Cdd:COG2319 106 DLATGLLLRTLtGHTGAVRSVAFSPDGKTLASGS--ADG----TVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLAS 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1363 VGDynDQTLALWSTYTYELLSSTRI-SEPVHDVAFSPFSHReMACVGK-GAIMFWLLEQHGADINLKVHRAPVpevlgpv 1440
Cdd:COG2319 180 GSD--DGTVRLWDLATGKLLRTLTGhTGAVRSVAFSPDGKL-LASGSAdGTVRLWDLATGKLLRTLTGHSGSV------- 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1441 elTSLCYGAD-TLLYSGTNSGQVCVWDTETNSCFMTWEADEGEI--------GmlvcrcNRLVSGSNTKRIRLWAVGAMQ 1511
Cdd:COG2319 250 --RSVAFSPDgRLLASGSADGTVRLWDLATGELLRTLTGHSGGVnsvafspdG------KLLASGSDDGTVRLWDLATGK 321
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1512 ELR-LKGPKGRPSSVllehEITLDGTIVSMAFDDslemgivgttaGTLWYINWKESTSIRLISGHKSKVTEVSFSPDETL 1590
Cdd:COG2319 322 LLRtLTGHTGAVRSV----AFSPDGKTLASGSDD-----------GTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRT 386
|
330
....*....|....*
gi 2024356826 1591 CATCGEDGSVRVWSL 1605
Cdd:COG2319 387 LASGSADGTVRLWDL 401
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
486-853 |
8.81e-33 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 133.11 E-value: 8.81e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 486 QIQTGEQ-RFFTGHTDKVSALAFNGSSTLLASAQEGplGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLCGVGKD 564
Cdd:COG2319 106 DLATGLLlRTLTGHTGAVRSVAFSPDGKTLASGSAD--GTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDD 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 565 GhgktMVVVWNTAqvthGGEVLVLARAHTDVdIQTLKIaSFDDTRMVSCGRD-SVRLWRVRNGVLrscpVNLGEYHALEF 643
Cdd:COG2319 184 G----TVRLWDLA----TGKLLRTLTGHTGA-VRSVAF-SPDGKLLASGSADgTVRLWDLATGKL----LRTLTGHSGSV 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 644 TDLAFeeghSaarePDDRTLficsrsghvlevdyknvcvrsarrllpaelqdgagpgiainsisisstlcATGSADGYLR 723
Cdd:COG2319 250 RSVAF----S----PDGRLL--------------------------------------------------ASGSADGTVR 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 724 LWPLD-FSAVVLEAEHEAPVSSVCISPDGHKVLCTTTARSLGYLDIQSRGYSTLMRSHEDSI--LAFSVDGvwKQMATVS 800
Cdd:COG2319 272 LWDLAtGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVrsVAFSPDG--KTLASGS 349
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 2024356826 801 RDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHPTQRILACGFDSGVVRTFSLT 853
Cdd:COG2319 350 DDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLA 402
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
1426-1748 |
3.84e-29 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 119.36 E-value: 3.84e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1426 LKVHRAPVpevlgpvelTSLCYGADT-LLYSGTNSGQVCVWDTETNSCFMTWEADEGEIGMLVCRC--NRLVSGSNTKRI 1502
Cdd:cd00200 5 LKGHTGGV---------TCVAFSPDGkLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASAdgTYLASGSSDKTI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1503 RLWAVGamqelrlkgpKGRPSSVLLEHEitldGTIVSMAFDDSLEMGIVGTTAGTLWYINWKESTSIRLISGHKSKVTEV 1582
Cdd:cd00200 76 RLWDLE----------TGECVRTLTGHT----SYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSV 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1583 SFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLNQSCHCLAWKPhpsfsweaESQHVVAGYSDGTIRVFSIsRTEMEL 1662
Cdd:cd00200 142 AFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSP--------DGEKLLSSSSDGTIKLWDL-STGKCL 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1663 K-MHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTGMTVRILADHKGSAITVlqctrkqyhdfGVEGGELWLAT-SS 1740
Cdd:cd00200 213 GtLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSL-----------AWSPDGKRLASgSA 281
|
....*...
gi 2024356826 1741 DRRVSVWA 1748
Cdd:cd00200 282 DGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
1344-1654 |
4.43e-29 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 118.98 E-value: 4.43e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1344 HKTQVQAMAYSRDDRFLATVGDynDQTLALWSTYTYELLSSTRI-SEPVHDVAFSPFSHReMACVGK-GAIMFWLLEQHG 1421
Cdd:cd00200 8 HTGGVTCVAFSPDGKLLATGSG--DGTIKVWDLETGELLRTLKGhTGPVRDVAASADGTY-LASGSSdKTIRLWDLETGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1422 ADINLKVHRAPVpevlgpvelTSLCYGAD-TLLYSGTNSGQVCVWDTETNSCFMTWEADEGEIGML-VCRCNRLV-SGSN 1498
Cdd:cd00200 85 CVRTLTGHTSYV---------SSVAFSPDgRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVaFSPDGTFVaSSSQ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1499 TKRIRLWAVGAMQELRlkgpkgrpssVLLEHEitldGTIVSMAFDDSLEMGIVGTTAGTLWYINWKESTSIRLISGHKSK 1578
Cdd:cd00200 156 DGTIKLWDLRTGKCVA----------TLTGHT----GEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENG 221
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024356826 1579 VTEVSFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLNQSCHCLAWKPhpsfsweaESQHVVAGYSDGTIRVFS 1654
Cdd:cd00200 222 VNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSP--------DGKRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
1449-1888 |
1.13e-28 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 120.79 E-value: 1.13e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1449 ADTLLYSGTNSGQVCVWDTETNSCFMTWEADEGEIGMLVCRCN--RLVSGSNTKRIRLWAVGAMQELR-LKGPKGRPSSV 1525
Cdd:COG2319 47 DGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDgrLLASASADGTVRLWDLATGLLLRtLTGHTGAVRSV 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1526 llehEITLDG-TIVSMAFDDSLemgivgttagTLWyiNWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWS 1604
Cdd:COG2319 127 ----AFSPDGkTLASGSADGTV----------RLW--DLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWD 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1605 LGRMELVVQFQVLNQSCHCLAWKPhpsfsweaESQHVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMIL 1684
Cdd:COG2319 191 LATGKLLRTLTGHTGAVRSVAFSP--------DGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLA 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1685 SGGKDGMVAVSSPRTGMTVRILADHKGSAITVlqctrkqyhDFGVEGGelWLATSS-DRRVSVWasdwlkdkcellDWLS 1763
Cdd:COG2319 263 SGSADGTVRLWDLATGELLRTLTGHSGGVNSV---------AFSPDGK--LLASGSdDGTVRLW------------DLAT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1764 FPAPASPEGlgslppslaafcpweHGTLVyvgfgmqkealfyslrkkqvvekislpyfaTSLSLSPAARFMAVGFSERLL 1843
Cdd:COG2319 320 GKLLRTLTG---------------HTGAV------------------------------RSVAFSPDGKTLASGSDDGTV 354
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 2024356826 1844 RLQRCPAG-LPQDYAGHDDAVHLCRFAPAGRRLLTASH-SAVLVWEL 1888
Cdd:COG2319 355 RLWDLATGeLLRTLTGHTGAVTSVAFSPDGRTLASGSAdGTVRLWDL 401
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
1265-1604 |
8.43e-28 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 115.51 E-value: 8.43e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1265 WDPDTGFFAYTC--GCVIVVeDLHSGSQNHWL-GHVEEISTLAVSHDAQALASASGkrDGdshcQICIWNTQDGICTARL 1341
Cdd:cd00200 17 FSPDGKLLATGSgdGTIKVW-DLETGELLRTLkGHTGPVRDVAASADGTYLASGSS--DK----TIRLWDLETGECVRTL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1342 FHHKTQVQAMAYSRDDRFLATVGDynDQTLALWSTYTYELLSSTR-ISEPVHDVAFSPFshremacvgkgaimfwlleqh 1420
Cdd:cd00200 90 TGHTSYVSSVAFSPDGRILSSSSR--DKTIKVWDVETGKCLTTLRgHTDWVNSVAFSPD--------------------- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1421 gadinlkvhrapvpevlgpveltslcygaDTLLYSGTNSGQVCVWDTETNSCFMTWEADEGEIgmlvcRC-------NRL 1493
Cdd:cd00200 147 -----------------------------GTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEV-----NSvafspdgEKL 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1494 VSGSNTKRIRLWavgamqELRlkgpKGRPSSVLLEHEitldGTIVSMAFDDSLEMGIVGTTAGTLWYINWKESTSIRLIS 1573
Cdd:cd00200 193 LSSSSDGTIKLW------DLS----TGKCLGTLRGHE----NGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLS 258
|
330 340 350
....*....|....*....|....*....|.
gi 2024356826 1574 GHKSKVTEVSFSPDETLCATCGEDGSVRVWS 1604
Cdd:cd00200 259 GHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
495-893 |
8.32e-27 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 112.43 E-value: 8.32e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 495 FTGHTDKVSALAFNGSSTLLASAqeGPLGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLCGVGKDGhgktMVVVW 574
Cdd:cd00200 5 LKGHTGGVTCVAFSPDGKLLATG--SGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDK----TIRLW 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 575 NtaqvTHGGEVLVLARAHTDvDIQTLKIAsfDDTRMV-SCGRD-SVRLWRVRNGVLRSCPvnlgeyhaleftdlafeEGH 652
Cdd:cd00200 79 D----LETGECVRTLTGHTS-YVSSVAFS--PDGRILsSSSRDkTIKVWDVETGKCLTTL-----------------RGH 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 653 SAarepddrtlficsrsghvlevDYKNVCVRSARRLLpaelqdgagpgiainsisisstlcATGSADGYLRLWplDFSAV 732
Cdd:cd00200 135 TD---------------------WVNSVAFSPDGTFV------------------------ASSSQDGTIKLW--DLRTG 167
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 733 VLEAE---HEAPVSSVCISPDGhkvlctttarslgyldiqsrgystlmrshedsilafsvdgvwKQMATVSRDNSIRVWD 809
Cdd:cd00200 168 KCVATltgHTGEVNSVAFSPDG------------------------------------------EKLLSSSSDGTIKLWD 205
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 810 LVSMQQLYDFTAAAEMPCAVSFHPTQRILACGFDSGVVRTFSLTASDLLTEHKQHRTRIAGLTFSPDGNFMFSSCLQGTL 889
Cdd:cd00200 206 LSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTI 285
|
....
gi 2024356826 890 ALYS 893
Cdd:cd00200 286 RIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
778-1078 |
4.13e-26 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 110.50 E-value: 4.13e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 778 RSHEDSI--LAFSVDGVWkqMATVSRDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHP-TQRILACGFDsGVVRTFSLTA 854
Cdd:cd00200 6 KGHTGGVtcVAFSPDGKL--LATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASAdGTYLASGSSD-KTIRLWDLET 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 855 SDLLTEHKQHRTRIAGLTFSPDGNFMFSSCLQGTLALYScvAQKSQVLRVLgnvvardagSGPDALVLSgdsrlLAFVGP 934
Cdd:cd00200 83 GECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWD--VETGKCLTTL---------RGHTDWVNS-----VAFSPD 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 935 SKYVVTvmeaCSLDELLRV-DISILDLNSTAL--DSAVR-ICFAPvSRGELLVSTSSNRILVLDAKTGRLVREVsPVHKL 1010
Cdd:cd00200 147 GTFVAS----SSQDGTIKLwDLRTGKCVATLTghTGEVNsVAFSP-DGEKLLSSSSDGTIKLWDLSTGKCLGTL-RGHEN 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024356826 1011 SCSSLALSKDaRYLLTAG--DKVIKVWDYRMRFDInfQVYIGHSEPVYQVAFTPDQQHVISVGD--AIFLWD 1078
Cdd:cd00200 221 GVNSVAFSPD-GYLLASGseDGTIRVWDLRTGECV--QTLSGHTNSVTSLAWSPDGKRLASGSAdgTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
1501-1888 |
8.89e-24 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 106.15 E-value: 8.89e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1501 RIRLWAVGAMQELRLKGPKGRPSSVLLEHEITLDGTIVSMAFDDSLEMGIVGTTAGTLWYINWKESTSIRLISGHKSKVT 1580
Cdd:COG2319 3 SADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1581 EVSFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLNQSCHCLAWKPhpsfsweaESQHVVAGYSDGTIRVFSISRTEM 1660
Cdd:COG2319 83 SVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSP--------DGKTLASGSADGTVRLWDLATGKL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1661 ELKMHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTGMTVRILADHKGSAITVlqctrkqyhDFGVEGGelWLATSS 1740
Cdd:COG2319 155 LRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSV---------AFSPDGK--LLASGS 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1741 -DRRVSVWasdwlkdkcellDWLSFPAPASPEGLGSLPPSLAaFCPweHGTLVYVGfGMQKEALFYSLRKKQVVEKISLP 1819
Cdd:COG2319 224 aDGTVRLW------------DLATGKLLRTLTGHSGSVRSVA-FSP--DGRLLASG-SADGTVRLWDLATGELLRTLTGH 287
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024356826 1820 YFA-TSLSLSPAARFMAVGFSERLLRLQRCPAG-LPQDYAGHDDAVHLCRFAPAGRRLLTASH-SAVLVWEL 1888
Cdd:COG2319 288 SGGvNSVAFSPDGKLLASGSDDGTVRLWDLATGkLLRTLTGHTGAVRSVAFSPDGKTLASGSDdGTVRLWDL 359
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
712-1036 |
6.28e-23 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 101.26 E-value: 6.28e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 712 LCATGSADGYLRLWPLDFSAVVLE-AEHEAPVSSVCISPDGHKVLCTTTARSLGYLDIQSRGYSTLMRSHEDSI--LAFS 788
Cdd:cd00200 23 LLATGSGDGTIKVWDLETGELLRTlKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVssVAFS 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 789 VDGVWkqMATVSRDNSIRVWDLVSMQQLYDFTAAAEMPCAVSFHPTQRILACGFDSGVVRTFSLTASDLLTEHKQHRTRI 868
Cdd:cd00200 103 PDGRI--LSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEV 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 869 AGLTFSPDGNFMFSSCLQGTLALYSCVAQKSQVLrvlgnvvardagsgpdalvlsgdsrllaFVGPSKYVVTVmeacsld 948
Cdd:cd00200 181 NSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGT----------------------------LRGHENGVNSV------- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 949 ellrvdisildlnstaldsavriCFAPVSRgeLLVSTSSNR-ILVLDAKTGRLVREVSpVHKLSCSSLALSKDARYLLTA 1027
Cdd:cd00200 226 -----------------------AFSPDGY--LLASGSEDGtIRVWDLRTGECVQTLS-GHTNSVTSLAWSPDGKRLASG 279
|
330
....*....|
gi 2024356826 1028 G-DKVIKVWD 1036
Cdd:cd00200 280 SaDGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
1522-1887 |
1.09e-21 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 97.41 E-value: 1.09e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1522 PSSVLLEHEitldGTIVSMAFDDSLEMGIVGTTAGTL--WyiNWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGS 1599
Cdd:cd00200 1 LRRTLKGHT----GGVTCVAFSPDGKLLATGSGDGTIkvW--DLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1600 VRVWSLGRMELVVQFQVLNQSCHCLAWKPHPSFsweaesqhVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTD 1679
Cdd:cd00200 75 IRLWDLETGECVRTLTGHTSYVSSVAFSPDGRI--------LSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPD 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1680 GEMILSGGKDGMVAVSSPRTGMTVRILADHKGSaitVLQCTrkqYHDfgvEGGELwLATSSDRRVSVWasdwlkdkcell 1759
Cdd:cd00200 147 GTFVASSSQDGTIKLWDLRTGKCVATLTGHTGE---VNSVA---FSP---DGEKL-LSSSSDGTIKLW------------ 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1760 dwlsfpapaspeglgslppSLAAfcpwehGTLVYVGFGMQKealfyslrkkqvvekislpyFATSLSLSPAARFMAVGFS 1839
Cdd:cd00200 205 -------------------DLST------GKCLGTLRGHEN--------------------GVNSVAFSPDGYLLASGSE 239
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1840 ERLLRL-QRCPAGLPQDYAGHDDAVHLCRFAPAGRRLLTASH-SAVLVWE 1887
Cdd:cd00200 240 DGTIRVwDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSAdGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
487-809 |
4.26e-21 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 95.86 E-value: 4.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 487 IQTGE-QRFFTGHTDKVSALAFNGSSTLLASAqeGPLGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLCGVGKDg 565
Cdd:cd00200 38 LETGElLRTLKGHTGPVRDVAASADGTYLASG--SSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRD- 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 566 hgKTmVVVWNTAQvthgGEVLVLARAHTDvDIQTLKIaSFDDTRMVSCGRD-SVRLWRVRNGVLRscpvnlgeyhaleft 644
Cdd:cd00200 115 --KT-IKVWDVET----GKCLTTLRGHTD-WVNSVAF-SPDGTFVASSSQDgTIKLWDLRTGKCV--------------- 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 645 dlafeeghsaarepddRTLficsrSGHvlevdykNVCVRSArRLLPaelqDGAgpgiainsisisstLCATGSADGYLRL 724
Cdd:cd00200 171 ----------------ATL-----TGH-------TGEVNSV-AFSP----DGE--------------KLLSSSSDGTIKL 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 725 W-PLDFSAVVLEAEHEAPVSSVCISPDGHKVLCTTTARSLGYLDIQSRGYSTLMRSHEDSILAFSVDGVWKQMATVSRDN 803
Cdd:cd00200 204 WdLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADG 283
|
....*.
gi 2024356826 804 SIRVWD 809
Cdd:cd00200 284 TIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
1541-1888 |
2.48e-14 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 77.26 E-value: 2.48e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1541 AFDDSLEMGIVGTTAGTLWYINWKESTSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLNQS 1620
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1621 CHCLAWKPHPsfsweaesQHVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTG 1700
Cdd:COG2319 81 VLSVAFSPDG--------RLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1701 MTVRILADHKGSAITVlqctrkqyhDFGVEGgeLWLATSS-DRRVSVWasDWLKDKCelldwlsfpapaspegLGSLPps 1779
Cdd:COG2319 153 KLLRTLTGHSGAVTSV---------AFSPDG--KLLASGSdDGTVRLW--DLATGKL----------------LRTLT-- 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1780 laafcpwEHGTLVYvgfgmqkealfyslrkkqvvekislpyfatSLSLSPAARFMAVGFSERLLRLQRCPAG-LPQDYAG 1858
Cdd:COG2319 202 -------GHTGAVR------------------------------SVAFSPDGKLLASGSADGTVRLWDLATGkLLRTLTG 244
|
330 340 350
....*....|....*....|....*....|.
gi 2024356826 1859 HDDAVHLCRFAPAGRRLLTASHS-AVLVWEL 1888
Cdd:COG2319 245 HSGSVRSVAFSPDGRLLASGSADgTVRLWDL 275
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
857-1081 |
1.45e-13 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 73.52 E-value: 1.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 857 LLTEHKQHRTRIAGLTFSPDGNFMFSSCLQGTLALYSCvaQKSQVLRVLGNvvardAGSGPDALVLSGDSRLLAfvgpsk 936
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDL--ETGELLRTLKG-----HTGPVRDVAASADGTYLA------ 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 937 yvvtvmeACSLDELLRV-DISILDLNSTAL--DSAVRiCFAPVSRGELLVSTSSNR-ILVLDAKTGRLVREVsPVHKLSC 1012
Cdd:cd00200 68 -------SGSSDKTIRLwDLETGECVRTLTghTSYVS-SVAFSPDGRILSSSSRDKtIKVWDVETGKCLTTL-RGHTDWV 138
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024356826 1013 SSLALSKDARYLLTAG-DKVIKVWDYR-MRFdinFQVYIGHSEPVYQVAFTPDQQHVISVGD--AIFLWDFLA 1081
Cdd:cd00200 139 NSVAFSPDGTFVASSSqDGTIKLWDLRtGKC---VATLTGHTGEVNSVAFSPDGEKLLSSSSdgTIKLWDLST 208
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
1626-1888 |
1.94e-11 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 66.97 E-value: 1.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1626 WKPHP----SFSWEAESQHVVAGYSDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTGM 1701
Cdd:cd00200 5 LKGHTggvtCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1702 TVRILADHKGSaitVLQCTrkqYHDfgveGGELWLATSSDRRVSVWasDWLKDKCElldwLSFPAPASPeglgslppslA 1781
Cdd:cd00200 85 CVRTLTGHTSY---VSSVA---FSP----DGRILSSSSRDKTIKVW--DVETGKCL----TTLRGHTDW----------V 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1782 AFCPWEHGTLVYVGFGMQKEALFYSLRKKQVVEKISLPY-FATSLSLSPAARFMAVGFSERLLRLQRCPAG-LPQDYAGH 1859
Cdd:cd00200 139 NSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTgEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGkCLGTLRGH 218
|
250 260 270
....*....|....*....|....*....|
gi 2024356826 1860 DDAVHLCRFAPAGRRLLTASH-SAVLVWEL 1888
Cdd:cd00200 219 ENGVNSVAFSPDGYLLASGSEdGTIRVWDL 248
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
1567-1604 |
1.59e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 49.23 E-value: 1.59e-07
10 20 30
....*....|....*....|....*....|....*...
gi 2024356826 1567 TSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWS 1604
Cdd:smart00320 3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
1566-1604 |
3.16e-07 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 48.11 E-value: 3.16e-07
10 20 30
....*....|....*....|....*....|....*....
gi 2024356826 1566 STSIRLISGHKSKVTEVSFSPDETLCATCGEDGSVRVWS 1604
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| Pgl |
COG2706 |
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism]; |
729-1028 |
1.85e-04 |
|
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
Pssm-ID: 442025 [Multi-domain] Cd Length: 352 Bit Score: 46.05 E-value: 1.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 729 FSAVVLEAEHEAPvSSVCISPDGHKVlctttarslgyldiqsrgYSTLmRSHEDSILAFSVD---GVWKQMATVSrdnsi 805
Cdd:COG2706 35 LTLLGLVAALGNP-SFLALSPDGRFL------------------YAVN-EVDDGGVSAFRIDpadGTLTLLNTVS----- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 806 rvwdlvsmqqlydftAAAEMPCAVSFHPTQRILACG-FDSGVVRTFSLTASDLLTEHKQ---------HRTRIAG----- 870
Cdd:COG2706 90 ---------------SGGASPCHLSVDPDGRFLFVAnYGGGSVSVFPIDADGSLGEPVQviqhegsgpNPERQEGphahs 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 871 LTFSPDGNFMFSSCLqGT--LALYScVAQKSQVLRVLGNVVARdAGSGPDALVLSGDSRLLafvgpskYVVTVM----EA 944
Cdd:COG2706 155 VVFDPDGRFLYVPDL-GTdrIYVYR-LDPATGKLPEPPEVSLP-PGSGPRHLAFHPNGRFA-------YVINELdstvSV 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 945 CSLDE----LLRVD-ISILDLNSTALDSAVRICFAPVSRgELLVS-TSSNRILVL--DAKTGRL-------VREVSPVHk 1009
Cdd:COG2706 225 YAYDAatgtLTLIQtVSTLPEDFTGENWAADIHISPDGR-FLYVSnRGHNSIAVFaiDADGGKLtlvghvpTGGKWPRD- 302
|
330
....*....|....*....
gi 2024356826 1010 lscssLALSKDARYLLTAG 1028
Cdd:COG2706 303 -----FAIDPDGRFLLVAN 316
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
1551-1626 |
2.98e-03 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 38.80 E-value: 2.98e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024356826 1551 VGTTAGTLWY--INWKESTSIRLiSGHKSKVTEVSFSPDETLCATCGEDGSVRVWSLGRMELVVQFQVLNQSCHCLAW 1626
Cdd:pfam12894 12 LATEDGELLLhrLNWQRVWTLSP-DKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGW 88
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
1571-1795 |
5.32e-03 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 41.42 E-value: 5.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1571 LISGHKSKVTEVSFSP-DETLCATCGEDGSVRVWSLGRMEL-------VVQFQVLNQSCHCLAWkpHPSfsweAESQHVV 1642
Cdd:PTZ00421 70 ILLGQEGPIIDVAFNPfDPQKLFTASEDGTIMGWGIPEEGLtqnisdpIVHLQGHTKKVGIVSF--HPS----AMNVLAS 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024356826 1643 AGySDGTIRVFSISRTEMELKMHPHATALTAIAYSTDGEMILSGGKDGMVAVSSPRTGMTVRILADHKGS-AITVLQCTR 1721
Cdd:PTZ00421 144 AG-ADMVVNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAkSQRCLWAKR 222
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024356826 1722 KqyhDFGVEGGelwLATSSDRRVSVWasdwlkdkcellDWLSFPAPASPEGLGSlppSLAAFCPW--EHGTLVYVG 1795
Cdd:PTZ00421 223 K---DLIITLG---CSKSQQRQIMLW------------DTRKMASPYSTVDLDQ---SSALFIPFfdEDTNLLYIG 277
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
497-564 |
6.10e-03 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 41.42 E-value: 6.10e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024356826 497 GHTDKVSALAFNGSST-LLASAqeGPLGVLRLWDFPKGSCLAVFQTHLRAVLSLSFSYSGAVLCGVGKD 564
Cdd:PTZ00421 123 GHTKKVGIVSFHPSAMnVLASA--GADMVVNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKD 189
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
777-809 |
9.62e-03 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 35.75 E-value: 9.62e-03
10 20 30
....*....|....*....|....*....|...
gi 2024356826 777 MRSHEDSILAFSVDGVWKQMATVSRDNSIRVWD 809
Cdd:smart00320 8 LKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| |
