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Conserved domains on  [gi|1567516499|ref|XP_027835222|]
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zinc finger protein 214 isoform X3 [Ovis aries]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
149-513 5.63e-12

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 67.80  E-value: 5.63e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 149 VLHKRNQLGEKLYPCSiSPTCFPQRSD---LYRHPRIHTGEQLYRC----------------DEVASNFSQSFGVHFHQR 209
Cdd:COG5048    50 TRHIRSHTGEKPSQCS-YSGCDKSFSRpleLSRHLRTHHNNPSDLNskslplsnskasssslSSSSSNSNDNNLLSSHSL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 210 AHPGEVPYICNLCSNSFSQIPRLHHHQRFHLEEKLYKLQ--------CDKDLGRNSLLHIHQRLHIGEKPFKCDQCGKSF 281
Cdd:COG5048   129 PPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLhpplpansLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSS 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 282 SRSSVLHVHQRVHTGEKPYKCDECGKGFSQSSNLRIHQ------LVHTGEKSYKCGDCGKGFTQRSNLQIHQRVHTG-EK 354
Cdd:COG5048   209 YSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSslsssdSSSSASESPRSSLPTASSQSSSPNESDSSSEKGfSL 288

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 355 PYKCDTCGKDFSHSSDLRIHQR--VHTGE--KPYICHE--CGKGFSKSSKLHTHQRVHTGEKPYKC--EQCGKGFSQRSH 426
Cdd:COG5048   289 PIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLN 368

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 427 LLIHQRV--HTGEKPYKCDDCGKGFS-------HSSNLHIHQRIHTGEKPYQCAKCGKGFSHSSALRIHQRVHTGEKTYK 497
Cdd:COG5048   369 NEPPQSLqqYKDLKNDKKSETLSNSCirnfkrdSNLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLL 448

                         410
                  ....*....|....*.
gi 1567516499 498 CHEYYKgFNQNSHLYN 513
Cdd:COG5048   449 CSILKS-FRRDLDLSN 463
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
149-513 5.63e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 67.80  E-value: 5.63e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 149 VLHKRNQLGEKLYPCSiSPTCFPQRSD---LYRHPRIHTGEQLYRC----------------DEVASNFSQSFGVHFHQR 209
Cdd:COG5048    50 TRHIRSHTGEKPSQCS-YSGCDKSFSRpleLSRHLRTHHNNPSDLNskslplsnskasssslSSSSSNSNDNNLLSSHSL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 210 AHPGEVPYICNLCSNSFSQIPRLHHHQRFHLEEKLYKLQ--------CDKDLGRNSLLHIHQRLHIGEKPFKCDQCGKSF 281
Cdd:COG5048   129 PPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLhpplpansLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSS 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 282 SRSSVLHVHQRVHTGEKPYKCDECGKGFSQSSNLRIHQ------LVHTGEKSYKCGDCGKGFTQRSNLQIHQRVHTG-EK 354
Cdd:COG5048   209 YSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSslsssdSSSSASESPRSSLPTASSQSSSPNESDSSSEKGfSL 288

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 355 PYKCDTCGKDFSHSSDLRIHQR--VHTGE--KPYICHE--CGKGFSKSSKLHTHQRVHTGEKPYKC--EQCGKGFSQRSH 426
Cdd:COG5048   289 PIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLN 368

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 427 LLIHQRV--HTGEKPYKCDDCGKGFS-------HSSNLHIHQRIHTGEKPYQCAKCGKGFSHSSALRIHQRVHTGEKTYK 497
Cdd:COG5048   369 NEPPQSLqqYKDLKNDKKSETLSNSCirnfkrdSNLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLL 448

                         410
                  ....*....|....*.
gi 1567516499 498 CHEYYKgFNQNSHLYN 513
Cdd:COG5048   449 CSILKS-FRRDLDLSN 463
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 270-322 6.03e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 6.03e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1567516499 270 KPFkCDQCGKSFSRSSVLHVHQRvhtgEKPYKCDECGKGFSQSSNLRIH-QLVH 322
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQK----AKHFKCHICHKKLYTAGGLAVHcLQVH 49
zf-H2C2_2 pfam13465
Zinc-finger double domain;
342-367 6.72e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 6.72e-04
                          10        20
                  ....*....|....*....|....*.
gi 1567516499 342 NLQIHQRVHTGEKPYKCDTCGKDFSH 367
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
149-513 5.63e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 67.80  E-value: 5.63e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 149 VLHKRNQLGEKLYPCSiSPTCFPQRSD---LYRHPRIHTGEQLYRC----------------DEVASNFSQSFGVHFHQR 209
Cdd:COG5048    50 TRHIRSHTGEKPSQCS-YSGCDKSFSRpleLSRHLRTHHNNPSDLNskslplsnskasssslSSSSSNSNDNNLLSSHSL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 210 AHPGEVPYICNLCSNSFSQIPRLHHHQRFHLEEKLYKLQ--------CDKDLGRNSLLHIHQRLHIGEKPFKCDQCGKSF 281
Cdd:COG5048   129 PPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLhpplpansLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSS 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 282 SRSSVLHVHQRVHTGEKPYKCDECGKGFSQSSNLRIHQ------LVHTGEKSYKCGDCGKGFTQRSNLQIHQRVHTG-EK 354
Cdd:COG5048   209 YSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSslsssdSSSSASESPRSSLPTASSQSSSPNESDSSSEKGfSL 288

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 355 PYKCDTCGKDFSHSSDLRIHQR--VHTGE--KPYICHE--CGKGFSKSSKLHTHQRVHTGEKPYKC--EQCGKGFSQRSH 426
Cdd:COG5048   289 PIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLN 368

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 427 LLIHQRV--HTGEKPYKCDDCGKGFS-------HSSNLHIHQRIHTGEKPYQCAKCGKGFSHSSALRIHQRVHTGEKTYK 497
Cdd:COG5048   369 NEPPQSLqqYKDLKNDKKSETLSNSCirnfkrdSNLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLL 448

                         410
                  ....*....|....*.
gi 1567516499 498 CHEYYKgFNQNSHLYN 513
Cdd:COG5048   449 CSILKS-FRRDLDLSN 463
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
255-499 3.92e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.39  E-value: 3.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 255 RNSLLHIHQRLHIGEKPFKC--DQCGKSFSRSSVLHVHQRVHTGEKP---------------------------YKCDEC 305
Cdd:COG5048    45 RLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSdlnskslplsnskasssslsssssnsnDNNLLS 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 306 GKGFSQSSNLRIHQLVHTGEKSYKCGD------------------------CGKGFTQRSNLQIHQRVHTGEKPYKCDTC 361
Cdd:COG5048   125 SHSLPPSSRDPQLPDLLSISNLRNNPLpgnnsssvntpqsnslhpplpansLSKDPSSNLSLLISSNVSTSIPSSSENSP 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 362 GKDFSHSSDLRIHQRVHTGEKPYICHECGKGFSKSSKLHTHQ------RVHTGEKPYKCEQCGKGFSQRSHLLIHQRVHT 435
Cdd:COG5048   205 LSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSslsssdSSSSASESPRSSLPTASSQSSSPNESDSSSEK 284

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1567516499 436 G-EKPYKCDDCGKGFSHSSNLHIHQR--IHTGE--KPYQC--AKCGKGFSHSSALRIHQRVHTGEKTYKCH 499
Cdd:COG5048   285 GfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEK 355
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
410-475 5.98e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.46  E-value: 5.98e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1567516499 410 KPYKCEQCGKGFSQRSHLLIHQRVHTGEKPYKC--DDCGKGFSHSSNLHIHQRIHTGEKPYQCAKCGK 475
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLP 99
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 275-379 2.36e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.55  E-value: 2.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 275 DQCGKSFSRSSVLHVHQR---------VHTGEKPYKCD--ECGKGFSQSSNLRIHQLvHtgeksykcGDCGKGFTQRSNL 343
Cdd:COG5189   316 LPCTNSSSNGKLAHGGERnidtpsrmlKVKDGKPYKCPveGCNKKYKNQNGLKYHML-H--------GHQNQKLHENPSP 386

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1567516499 344 QIHQRVHTGEKPYKCDTCGKDFSHSSDLRIHqRVHT 379
Cdd:COG5189   387 EKMNIFSAKDKPYRCEVCDKRYKNLNGLKYH-RKHS 421
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 270-322 6.03e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 6.03e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1567516499 270 KPFkCDQCGKSFSRSSVLHVHQRvhtgEKPYKCDECGKGFSQSSNLRIH-QLVH 322
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQK----AKHFKCHICHKKLYTAGGLAVHcLQVH 49
zf-H2C2_2 pfam13465
Zinc-finger double domain;
342-367 6.72e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 6.72e-04
                          10        20
                  ....*....|....*....|....*.
gi 1567516499 342 NLQIHQRVHTGEKPYKCDTCGKDFSH 367
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
438-491 1.88e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.83  E-value: 1.88e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1567516499 438 KPYKCDDCGKGFSHSSNLHIHQRIHTGEKPYQCAK--CGKGFSHSSALRIHQRVHT 491
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHH 87
zf-H2C2_2 pfam13465
Zinc-finger double domain;
426-451 3.82e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.82e-03
                          10        20
                  ....*....|....*....|....*.
gi 1567516499 426 HLLIHQRVHTGEKPYKCDDCGKGFSH 451
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
290-311 5.13e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 5.13e-03
                          10        20
                  ....*....|....*....|..
gi 1567516499 290 HQRVHTGEKPYKCDECGKGFSQ 311
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 440-462 6.47e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.20  E-value: 6.47e-03
                          10        20
                  ....*....|....*....|...
gi 1567516499 440 YKCDDCGKGFSHSSNLHIHQRIH 462
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 328-350 6.93e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.20  E-value: 6.93e-03
                          10        20
                  ....*....|....*....|...
gi 1567516499 328 YKCGDCGKGFTQRSNLQIHQRVH 350
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
402-423 7.84e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 7.84e-03
                          10        20
                  ....*....|....*....|..
gi 1567516499 402 HQRVHTGEKPYKCEQCGKGFSQ 423
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 352-435 9.28e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 38.55  E-value: 9.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1567516499 352 GEKPYKCDT--CGKDFSHSSDLRIHqRVHtGEKPYICHECGKGFSkssklhtHQRVHTGEKPYKCEQCGKGFSQRSHLLI 429
Cdd:COG5189   346 DGKPYKCPVegCNKKYKNQNGLKYH-MLH-GHQNQKLHENPSPEK-------MNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ....*.
gi 1567516499 430 HqRVHT 435
Cdd:COG5189   417 H-RKHS 421
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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