|
Name |
Accession |
Description |
Interval |
E-value |
| Tubulin-binding |
pfam00418 |
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
1956-1985 |
3.30e-15 |
|
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.
Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 70.90 E-value: 3.30e-15
10 20 30
....*....|....*....|....*....|
gi 987959268 1956 VQIVSKKLNYSHVQSKCGSKDNIKHVPGGG 1985
Cdd:pfam00418 1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
|
|
| Tubulin-binding |
pfam00418 |
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
1987-2016 |
9.45e-14 |
|
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.
Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 66.67 E-value: 9.45e-14
10 20 30
....*....|....*....|....*....|
gi 987959268 1987 VQIQSKKVDISKVSSKCGSKANIKHKPGGG 2016
Cdd:pfam00418 1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
166-600 |
6.60e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.97 E-value: 6.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 166 TRQSDPLRDRDSHGHLPCDTLTPEAVVPQDWPVEAPhgpqagafiSPEATPPLQPTAEPAGERETASEERASTRASgtmL 245
Cdd:PHA03247 2596 ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSP---------SPAANEPDPHPPPTVPPPERPRDDPAPGRVS---R 2663
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 246 ELKAADMAPSREAETALAQDMVPATETEVALATNVASPTKEDvsfaknmDSPIESDVAAVRDVVLPIEAKEtpAKGAVLL 325
Cdd:PHA03247 2664 PRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPP-------PTPEPAPHALVSATPLPPGPAA--ARQASPA 2734
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 326 RDTERAPPmemdAAPAAGVVSLTEREMALAKDTASPTAKelALSSGTEVAPVKGMAPPPETEVAPGKDMAP------PPE 399
Cdd:PHA03247 2735 LPAAPAPP----AVPAGPATPGGPARPARPPTTAGPPAP--APPAAPAAGPPRRLTRPAVASLSESRESLPspwdpaDPP 2808
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 400 TEGLGMAPPPETEVAPVKGMAPPPETEVAPVKGMAPPPEIEVASVKGMAP-------PPETEVVPVKGMAPPPETEVVPV 472
Cdd:PHA03247 2809 AAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPggdvrrrPPSRSPAAKPAAPARPPVRRLAR 2888
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 473 KGVAPPPETEVTPGKDVPLLPEPEPSlakdvVPPSETEVAPVPAKDMGTVRTPGKPSEGPQfaslrnegPSAVPAAVASP 552
Cdd:PHA03247 2889 PAVSRSTESFALPPDQPERPPQPQAP-----PPPQPQPQPPPPPQPQPPPPPPPRPQPPLA--------PTTDPAGAGEP 2955
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 987959268 553 EPVTAVGQTSALPPDEASVPEKLEQRQPLSRQPPEPPAAPSGTLPTPA 600
Cdd:PHA03247 2956 SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR 3003
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1330-1890 |
1.60e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.80 E-value: 1.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1330 EATSTPAPPEA--LHSAACEKLPTPHPqlvkGGEAFTGNLAESR---QGTALAQISEWSVVGHCSKDGVPEQERATAA-- 1402
Cdd:PHA03247 2413 EQPDPPGPPDVrfVGSEEIEELPFVSP----GGDVLAGLAADGDpffARTILGAPFSLSLLLGELFPGAPVYRRPAEArf 2488
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1403 -SAARPCASPGGGALTLPAATETGQRPRDCC--------PEHKEQLA--EPMENEAGVDGGHVGGESESGPRGAS----- 1466
Cdd:PHA03247 2489 pFAAGAAPDPGGGGPPDPDAPPAPSRLAPAIlpdepvgePVHPRMLTwiRGLEELASDDAGDPPPPLPPAAPPAApdrsv 2568
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1467 --KRPAEEITEPAKGPR------PAVPTADQSPRPERGGPGVRAGGSPVPASPVNREGEAGAGSASSHTADFPGDGPQKP 1538
Cdd:PHA03247 2569 ppPRPAPRPSEPAVTSRarrpdaPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPP 2648
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1539 LCCEDQHAEGG-ASRGPTGLNKEMEMTLSTPKSEQDKREGSSLAPKITESAD--APLPAPALQSDFFNGQLGAAPSSAVE 1615
Cdd:PHA03247 2649 PERPRDDPAPGrVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADppPPPPTPEPAPHALVSATPLPPGPAAA 2728
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1616 KLAVTACQGLPLPEPEEKASEAPEKMTEKPEPKALGEGKKE---EKRAAEPLKGYMRP-----TKSRGLAPLSPKPAAVQ 1687
Cdd:PHA03247 2729 RQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPappAAPAAGPPRRLTRPavaslSESRESLPSPWDPADPP 2808
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1688 ERGRPEHATPSGTAKPEGPAAASVTGNDITAPPNKELPPSPEKKAKVVA-GMPVAetKVPEKKATPSKPAsAPASRPGSR 1766
Cdd:PHA03247 2809 AAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVApGGDVR--RRPPSRSPAAKPA-APARPPVRR 2885
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1767 STQAAPKAPAAASVASTGPSSRSAPTPLPRRPAGTKTEGKPADAKKAVTKSAPADLSRAKSTSSSTARKTAAGPGPGSPA 1846
Cdd:PHA03247 2886 LARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLG 2965
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 987959268 1847 GAAPSRVK-PTPVSPRASGTLAVDKKPTSARPSSLAPRLSRPATS 1890
Cdd:PHA03247 2966 ALVPGRVAvPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASS 3010
|
|
| Tubulin-binding |
pfam00418 |
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
1895-1916 |
5.23e-07 |
|
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.
Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 47.41 E-value: 5.23e-07
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
387-910 |
1.19e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 54.17 E-value: 1.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 387 EVAPGKDMAPPPETEGLGMAPPPETEVAPVKGMAPPPEtevAPVKGMAPPPEIEVASVKGMAP--PPETEVVPVKGMAPP 464
Cdd:PHA03247 2542 ELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSE---PAVTSRARRPDAPPQSARPRAPvdDRGDPRGPAPPSPLP 2618
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 465 PETEVVPVKGVAPPPETEVTPGKDVPLLPEPE----PSLAKDVVPPSETEVAPVPAKDMGTVRTPGKPSEGPQFASLRNE 540
Cdd:PHA03247 2619 PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPErprdDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSL 2698
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 541 GPSAVPAAVASPEPVTAVGQTSALPpdeasVPEKLEQRQPLSRQPPEPPAAPSGTLpTPAKQVCRPRDRRAARPRPARVP 620
Cdd:PHA03247 2699 ADPPPPPPTPEPAPHALVSATPLPP-----GPAAARQASPALPAAPAPPAVPAGPA-TPGGPARPARPPTTAGPPAPAPP 2772
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 621 PELLGGSSPKTLDPGLGPCSVLEPGWVSGSVPCGEPGSQrkTTPAAFPETQREPGRQAWEAESTAMMKKKKKRPKQKRCS 700
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV--LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL 2850
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 701 PPRGGGPWGDDSAREADGRPVAADPQKPgvrpsqpatvggQHAPASRespeedggvdagTAKPAAeSLVSESPRVPSCPW 780
Cdd:PHA03247 2851 PLGGSVAPGGDVRRRPPSRSPAAKPAAP------------ARPPVRR------------LARPAV-SRSTESFALPPDQP 2905
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 781 EEPPKAAVNSQPKLSREAEVkgnKSEPQSQDReslQQGGCKPQTAPHLATPLRPEGSlpevsaHKIEAPWEVRAQEGCFP 860
Cdd:PHA03247 2906 ERPPQPQAPPPPQPQPQPPP---PPQPQPPPP---PPPRPQPPLAPTTDPAGAGEPS------GAVPQPWLGALVPGRVA 2973
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 987959268 861 VSDQEAPGPvVKPTAAKELPNPTRTLTANNPLES-----SLKEGSDGRTVPALQT 910
Cdd:PHA03247 2974 VPRFRVPQP-APSREAPASSTPPLTGHSLSRVSSwasslALHEETDPPPVSLKQT 3027
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
421-738 |
2.26e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 46.68 E-value: 2.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 421 PPPETEVAPVKGMAPPPEIEVASVKGMAPPPETEVVPVKGMAPPPETEVVPVKGVAPPPETEVTPGKDVPLLPEPEPSLA 500
Cdd:pfam03154 171 PPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQ 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 501 KDVVPPSETEVAPVPakdmgtVRTPGKPSEGPQFASLRNEGPSAVPAAVAS----PEPVTAVGQTSALPPDEASVPEKLE 576
Cdd:pfam03154 251 PMTQPPPPSQVSPQP------LPQPSLHGQMPPMPHSLQTGPSHMQHPVPPqpfpLTPQSSQSQVPPGPSPAAPGQSQQR 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 577 QRQPLSR------QPPEPPAAPSGTLPTPAKQVCRPRDRRAARPRPARVPPELLGGSSPKTLDPGLGPCSVLEPgwvSGS 650
Cdd:pfam03154 325 IHTPPSQsqlqsqQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKP---LSS 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 651 VPCGEPGSQRKTTPAAFPETQREPGRQAWEAESTAMMKKKKKRPKQKRCS-----------PPRGGGPWGDDSAREADGR 719
Cdd:pfam03154 402 LSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSglhqvpsqspfPQHPFVPGGPPPITPPSGP 481
|
330
....*....|....*....
gi 987959268 720 PVAADPQKPGVRPSQPATV 738
Cdd:pfam03154 482 PTSTSSAMPGIQPPSSASV 500
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
1558-1885 |
4.27e-04 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 45.76 E-value: 4.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1558 NKEMEMTLSTPKSEQDKREGSSLAPKITESADaplpapalqsdffngqlGAAPSSAVEKLAVTacqglplpePEEKASEA 1637
Cdd:TIGR00927 69 NDEMMMVSSDPPKSSSEMEGEMLAPQATVGRD-----------------EATPSIAMENTPSP---------PRRTAKIT 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1638 PEKMTEKPEPKALGEGKKEEKRAAEPLK--GYMRPTKSRGLA-PLSPKP-------AAVQERGRPEHATPSGTAKPEGPA 1707
Cdd:TIGR00927 123 PTTPKNNYSPTAAGTERVKEDTPATPSRalNHYISTSGRQRVkSYTPKPrgevkssSPTQTREKVRKYTPSPLGRMVNSY 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1708 AASVTgndITAPPNKELPP-SPEKKAKVVAGMPVAETK-----------VPEKKATPSKPA-----------SAPASRPG 1764
Cdd:TIGR00927 203 APSTF---MTMPRSHGITPrTTVKDSEITATYKMLETNpskrtagkttpTPLKGMTDNTPTfltrevetdllTSPRSVVE 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1765 SRSTQAAPKAPAAASVASTGPSSRSAPTPlprrPAGTKTEGKPADAKKAVTKSAPADLSRAKsTSSSTARKTAAGPGPGS 1844
Cdd:TIGR00927 280 KNTLTTPRRVESNSSTNHWGLVGKNNLTT----PQGTVLEHTPATSEGQVTISIMTGSSPAE-TKASTAAWKIRNPLSRT 354
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1845 PAGAA-------------PSRVKPTPVSP--RASGTLAVDK----KPTSARPSSLAPRLS 1885
Cdd:TIGR00927 355 SAPAVriasatfrgleknPSTAPSTPATPrvRAVLTTQVHHcvvvKPAPAVPTTPSPSLT 414
|
|
| KAR9 |
pfam08580 |
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ... |
1693-1893 |
7.80e-04 |
|
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.
Pssm-ID: 430088 [Multi-domain] Cd Length: 684 Bit Score: 44.44 E-value: 7.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1693 EHATPSGTAKPEGPAAASVT---GNDITAPPNKELPPSPEKKA---KVVAGMPVAETKVPEKKAT---PSKPASAPASRP 1763
Cdd:pfam08580 420 SPATLVANKTPGSSPPSSVImtpVNKGSKTPSSRRGSSFDFGSsseRVINSKLRRESKLPQIASTlkqTKRPSKIPRASP 499
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1764 GSRSTQAAPKAPAAASV--ASTGPSSRSAPTPLPRRPAGTKTEgKPADAKKAVTKSaPADLSRAKSTSSSTARKTAAGPG 1841
Cdd:pfam08580 500 NHSGFLSTPSNTATSETptPALRPPSRPQPPPPGNRPRWNAST-NTNDLDVGHNFK-PLTLTTPSPTPSRSSRSSSTLPP 577
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 987959268 1842 PGSPAGAAPSRVKPTPVSPRASGTLAVDKKPT-SARPSSLAPRLSRPATSAST 1893
Cdd:pfam08580 578 VSPLSRDKSRSPAPTCRSVSRASRRRASRKPTrIGSPNSRTSLLDEPPYPKLT 630
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
389-599 |
1.70e-03 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 43.22 E-value: 1.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 389 APGKDMAPPPETEGLGMAPPPETEVAPVKGMAPPPETEVapvkgmAPPPEIEVASVKGMAPPPETEV-----VPVKGMAP 463
Cdd:NF033839 294 APKPGMQPSPQPEKKEVKPEPETPKPEVKPQLEKPKPEV------KPQPEKPKPEVKPQLETPKPEVkpqpeKPKPEVKP 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 464 PPETevvPVKGVAPPPETEVTPGKDVPLLPEPEPSLAKDVVPPSETEVAPVPAKDMGTVRTPGKPSEGPQFASlrnegps 543
Cdd:NF033839 368 QPEK---PKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEK------- 437
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 987959268 544 avPAAVASPEPVTAvgqtsalPPDEASVPEKLEQRQPLSRQPPEPPAAPSGTLPTP 599
Cdd:NF033839 438 --PKPEVKPQPEKP-------KPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKP 484
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
1456-1851 |
3.06e-03 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 42.45 E-value: 3.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1456 GESESGPRGASKRPAEEITEPAKGPRPAVPTADQSPRPErggpgvrAGGSPVPASPVNREGEAGAGSASSHTADFPGDGP 1535
Cdd:NF033839 146 DSSSSSSSGSSTKPETPQPENPEHQKPTTPAPDTKPSPQ-------PEGKKPSVPDINQEKEKAKLAVATYMSKILDDIQ 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1536 QKPLCCEDQHAEGGASRGPTGLNKEMEMTLSTPKSeqdKREGSSLAPKITESADAPLpapalqSDFFNGQLGAAPSSAVE 1615
Cdd:NF033839 219 KHHLQKEKHRQIVALIKELDELKKQALSEIDNVNT---KVEIENTVHKIFADMDAVV------TKFKKGLTQDTPKEPGN 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1616 KLAVTACQGL-PLPEPEEKASEA----------PEKMTEKPEPKALGEGKKEE-KRAAEPLKGYMRPTKSRGLAPLSPKP 1683
Cdd:NF033839 290 KKPSAPKPGMqPSPQPEKKEVKPepetpkpevkPQLEKPKPEVKPQPEKPKPEvKPQLETPKPEVKPQPEKPKPEVKPQP 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1684 AAVQERGRPEHATPSGTAKPEgPAAASVTGNDITAPPNKELPPSPEKKAKVVAgmPVAETKVPEKKATPSKPASAPASRP 1763
Cdd:NF033839 370 EKPKPEVKPQPETPKPEVKPQ-PEKPKPEVKPQPEKPKPEVKPQPEKPKPEVK--PQPEKPKPEVKPQPEKPKPEVKPQP 446
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1764 GSRSTQAAPKAPAAASVASTGPSS-RSAPTPLPRRPAGTKTEGKPADAKKAVTKSAPADlsRAKSTSSSTARKTAAGPGP 1842
Cdd:NF033839 447 EKPKPEVKPQPETPKPEVKPQPEKpKPEVKPQPEKPKPDNSKPQADDKKPSTPNNLSKD--KQPSNQASTNEKATNKPKK 524
|
....*....
gi 987959268 1843 GSPAGAAPS 1851
Cdd:NF033839 525 SLPSTGSIS 533
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Tubulin-binding |
pfam00418 |
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
1956-1985 |
3.30e-15 |
|
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.
Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 70.90 E-value: 3.30e-15
10 20 30
....*....|....*....|....*....|
gi 987959268 1956 VQIVSKKLNYSHVQSKCGSKDNIKHVPGGG 1985
Cdd:pfam00418 1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
|
|
| Tubulin-binding |
pfam00418 |
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
1987-2016 |
9.45e-14 |
|
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.
Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 66.67 E-value: 9.45e-14
10 20 30
....*....|....*....|....*....|
gi 987959268 1987 VQIQSKKVDISKVSSKCGSKANIKHKPGGG 2016
Cdd:pfam00418 1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
166-600 |
6.60e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.97 E-value: 6.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 166 TRQSDPLRDRDSHGHLPCDTLTPEAVVPQDWPVEAPhgpqagafiSPEATPPLQPTAEPAGERETASEERASTRASgtmL 245
Cdd:PHA03247 2596 ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSP---------SPAANEPDPHPPPTVPPPERPRDDPAPGRVS---R 2663
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 246 ELKAADMAPSREAETALAQDMVPATETEVALATNVASPTKEDvsfaknmDSPIESDVAAVRDVVLPIEAKEtpAKGAVLL 325
Cdd:PHA03247 2664 PRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPP-------PTPEPAPHALVSATPLPPGPAA--ARQASPA 2734
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 326 RDTERAPPmemdAAPAAGVVSLTEREMALAKDTASPTAKelALSSGTEVAPVKGMAPPPETEVAPGKDMAP------PPE 399
Cdd:PHA03247 2735 LPAAPAPP----AVPAGPATPGGPARPARPPTTAGPPAP--APPAAPAAGPPRRLTRPAVASLSESRESLPspwdpaDPP 2808
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 400 TEGLGMAPPPETEVAPVKGMAPPPETEVAPVKGMAPPPEIEVASVKGMAP-------PPETEVVPVKGMAPPPETEVVPV 472
Cdd:PHA03247 2809 AAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPggdvrrrPPSRSPAAKPAAPARPPVRRLAR 2888
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 473 KGVAPPPETEVTPGKDVPLLPEPEPSlakdvVPPSETEVAPVPAKDMGTVRTPGKPSEGPQfaslrnegPSAVPAAVASP 552
Cdd:PHA03247 2889 PAVSRSTESFALPPDQPERPPQPQAP-----PPPQPQPQPPPPPQPQPPPPPPPRPQPPLA--------PTTDPAGAGEP 2955
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 987959268 553 EPVTAVGQTSALPPDEASVPEKLEQRQPLSRQPPEPPAAPSGTLPTPA 600
Cdd:PHA03247 2956 SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR 3003
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
156-679 |
1.45e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.80 E-value: 1.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 156 PSGAHGASALTRQSDPLRDRDSHGHLPCDTLTPEAVVPQDWPVEAPHGPQAGAFI----------SPEATPPLQPTAEPA 225
Cdd:PHA03247 2483 PAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRMLTWIrgleelasddAGDPPPPLPPAAPPA 2562
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 226 GERETASEERASTRASGTMLELKAAdmAPSREAETALAQdmVPATETEVALATNVASPTKEDvsfAKNMDSPIESDVAAv 305
Cdd:PHA03247 2563 APDRSVPPPRPAPRPSEPAVTSRAR--RPDAPPQSARPR--APVDDRGDPRGPAPPSPLPPD---THAPDPPPPSPSPA- 2634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 306 rdvvlpieAKETPAKGAVllrdtERAPPMEMDAAPAAGVVSLTEREMALAKDT--ASPTAKELALSSGTEVAPVKGMAPP 383
Cdd:PHA03247 2635 --------ANEPDPHPPP-----TVPPPERPRDDPAPGRVSRPRRARRLGRAAqaSSPPQRPRRRAARPTVGSLTSLADP 2701
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 384 PETEVAPgkDMAPPPETEGLGMAPPPET--EVAPVKGMAP----PPETEVAPVKGMAP--------PPEIEVASVKGMAP 449
Cdd:PHA03247 2702 PPPPPTP--EPAPHALVSATPLPPGPAAarQASPALPAAPappaVPAGPATPGGPARParppttagPPAPAPPAAPAAGP 2779
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 450 PPETEVVPVKGMAPPPETEVVPVKGVAPP----PETEVTPGKDVPLLPEPEPSLAKDVVPPSETEVAPVPAKDMGTVRTP 525
Cdd:PHA03247 2780 PRRLTRPAVASLSESRESLPSPWDPADPPaavlAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPG 2859
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 526 GKPSEGPQFASlrnegPSAVPAAVASPePVTAVGQTSALPPDEASVPEKLEQRQPLSRQPPEPPAAPSGTLPTPAKQVCR 605
Cdd:PHA03247 2860 GDVRRRPPSRS-----PAAKPAAPARP-PVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 987959268 606 PRDRRAARPRPARVPPELLGGSSPKTLDPGLGPCSVLEPGWVSGSVPCGEPGSQRKTTPAAFPETQREPGRQAW 679
Cdd:PHA03247 2934 PPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSW 3007
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1330-1890 |
1.60e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 63.80 E-value: 1.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1330 EATSTPAPPEA--LHSAACEKLPTPHPqlvkGGEAFTGNLAESR---QGTALAQISEWSVVGHCSKDGVPEQERATAA-- 1402
Cdd:PHA03247 2413 EQPDPPGPPDVrfVGSEEIEELPFVSP----GGDVLAGLAADGDpffARTILGAPFSLSLLLGELFPGAPVYRRPAEArf 2488
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1403 -SAARPCASPGGGALTLPAATETGQRPRDCC--------PEHKEQLA--EPMENEAGVDGGHVGGESESGPRGAS----- 1466
Cdd:PHA03247 2489 pFAAGAAPDPGGGGPPDPDAPPAPSRLAPAIlpdepvgePVHPRMLTwiRGLEELASDDAGDPPPPLPPAAPPAApdrsv 2568
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1467 --KRPAEEITEPAKGPR------PAVPTADQSPRPERGGPGVRAGGSPVPASPVNREGEAGAGSASSHTADFPGDGPQKP 1538
Cdd:PHA03247 2569 ppPRPAPRPSEPAVTSRarrpdaPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPP 2648
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1539 LCCEDQHAEGG-ASRGPTGLNKEMEMTLSTPKSEQDKREGSSLAPKITESAD--APLPAPALQSDFFNGQLGAAPSSAVE 1615
Cdd:PHA03247 2649 PERPRDDPAPGrVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADppPPPPTPEPAPHALVSATPLPPGPAAA 2728
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1616 KLAVTACQGLPLPEPEEKASEAPEKMTEKPEPKALGEGKKE---EKRAAEPLKGYMRP-----TKSRGLAPLSPKPAAVQ 1687
Cdd:PHA03247 2729 RQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPappAAPAAGPPRRLTRPavaslSESRESLPSPWDPADPP 2808
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1688 ERGRPEHATPSGTAKPEGPAAASVTGNDITAPPNKELPPSPEKKAKVVA-GMPVAetKVPEKKATPSKPAsAPASRPGSR 1766
Cdd:PHA03247 2809 AAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVApGGDVR--RRPPSRSPAAKPA-APARPPVRR 2885
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1767 STQAAPKAPAAASVASTGPSSRSAPTPLPRRPAGTKTEGKPADAKKAVTKSAPADLSRAKSTSSSTARKTAAGPGPGSPA 1846
Cdd:PHA03247 2886 LARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLG 2965
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 987959268 1847 GAAPSRVK-PTPVSPRASGTLAVDKKPTSARPSSLAPRLSRPATS 1890
Cdd:PHA03247 2966 ALVPGRVAvPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASS 3010
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
326-520 |
8.37e-09 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 59.96 E-value: 8.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 326 RDTERAPPMEMDAAPAAGVvslteREMALAKDTASPTAKElalsSGTEVAPVKGMAPPPETEVAPGKdmapppeteglGM 405
Cdd:PTZ00436 181 REKDRERARREDAAAAAAA-----KQKAAAKKAAAPSGKK----SAKAAAPAKAAAAPAKAAAPPAK-----------AA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 406 APPPETEVAPVKGMAPPPETEVAPVKGMAPPPEIEVASVKGMAPPPETEVVPVKGMAPPPETEVVPVKGVAPPPETEVTP 485
Cdd:PTZ00436 241 AAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPP 320
|
170 180 190
....*....|....*....|....*....|....*
gi 987959268 486 GKDVPLLPEPEPSLAKDVVPPSETEVAPVPAKDMG 520
Cdd:PTZ00436 321 AKAAAPPAKAATPPAKAAAPPAKAAAAPVGKKAGG 355
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1471-1894 |
8.77e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.03 E-value: 8.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1471 EEITEPAKGPRPAVPTADQSPRPERGGPGVRAGGSPVPASPVNREGEAGAgSASSHTADFPGDGPqkplccedqhaegGA 1550
Cdd:PHA03247 2542 ELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDA-PPQSARPRAPVDDR-------------GD 2607
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1551 SRGPTGLNKEMEMTLSTPKSEQDKREGSSLAPKITESADAPLPAPalqsdffngQLGAAPSSAVEKLAVTAcqglplPEP 1630
Cdd:PHA03247 2608 PRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERP---------RDDPAPGRVSRPRRARR------LGR 2672
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1631 EEKASEAPEKMTEKPEPKALGEGKKEEKRAAEPLKGYMRPTKSRGLAPLSPKPAAVQERGRPEHATPSGTAKPEGPAAaS 1710
Cdd:PHA03247 2673 AAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT-P 2751
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1711 VTGNDITAPPNKELPPSPEKKAKVVAGMPVAETKVPEKKATPSKPASAPASRPGSRStqAAPKAPAAASVASTGPSSRSA 1790
Cdd:PHA03247 2752 GGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPP--AAVLAPAAALPPAASPAGPLP 2829
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1791 PTPLPRRPAGTKTEGKPADAKKAVTKSAPADLSRAKSTSSSTARKTAAGPGPGSPAGAAPSRVKPTPVSPRASGTLAVDK 1870
Cdd:PHA03247 2830 PPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPP 2909
|
410 420
....*....|....*....|....
gi 987959268 1871 KPTSARPSSLAPRLSRPATSASTP 1894
Cdd:PHA03247 2910 QPQAPPPPQPQPQPPPPPQPQPPP 2933
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1520-1918 |
2.39e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 56.33 E-value: 2.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1520 AGSASSHTADFPGDGPQKPLCCEDQHAE---GGASRGPTGLNKEMEMTLSTPKSEQDKREGSSLAPkITESADAPLPAPA 1596
Cdd:PHA03307 24 PPATPGDAADDLLSGSQGQLVSDSAELAavtVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPT-WSLSTLAPASPAR 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1597 LQSDffngqlGAAPSSAVEKLAVTACQGLPLPEPEEKASEAPeKMTEKPEPKALGEGKKEEKRAAEPLKGymrPTKSRGL 1676
Cdd:PHA03307 103 EGSP------TPPGPSSPDPPPPTPPPASPPPSPAPDLSEML-RPVGSPGPPPAASPPAAGASPAAVASD---AASSRQA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1677 APLSPKPAAVQERGRPEHATPSGTAKPEGPAAASVTGNDITAPPNKELPPSPEKKAKVVAG---MPVAETKVPEKKATPS 1753
Cdd:PHA03307 173 ALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGassSDSSSSESSGCGWGPE 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1754 KPASAPASRPGSRSTQAAPKAPAAASVASTGPSSRSAPTPLPRRPAGTKTEGKPADA--KKAVTKSAPADLSRAKSTSSS 1831
Cdd:PHA03307 253 NECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPssPRASSSSSSSRESSSSSTSSS 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1832 TARKTAAGPGPGSPAGAAPSRVKPTPVSPRASGTLAVDKKPTSARPSSLAPRLSRPATSASTPDLKNVRAKVGSTENIRH 1911
Cdd:PHA03307 333 SESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRP 412
|
....*..
gi 987959268 1912 QPGGGRA 1918
Cdd:PHA03307 413 RPSPLDA 419
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1480-1893 |
5.10e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 55.18 E-value: 5.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1480 PRPAVPTADQSPRPERGGPGVRAGGSPVPASPVNREGEAGAGSASSHTADFPGDGPqkplccEDQHAEGGASRGPTGLNK 1559
Cdd:PHA03307 22 PRPPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGT------EAPANESRSTPTWSLSTL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1560 EMEMTLSTPKSEQDKREGSSLAPKITESA-DAPLPAPALQSDFFNGQLGAAPSSAVEklavtacqglplPEPEEKASEAP 1638
Cdd:PHA03307 96 APASPAREGSPTPPGPSSPDPPPPTPPPAsPPPSPAPDLSEMLRPVGSPGPPPAASP------------PAAGASPAAVA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1639 EKMTEKPEPKALGEGKKEEKRAAEPLKGYMRPTKSRGLAPLSPKPAAVQERGRPEHATPSGTAKPEGPAAASVTGNDITA 1718
Cdd:PHA03307 164 SDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSE 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1719 PPNKELPPSPEkkakvvagmpvAETKVPEKKATPSKPASA-PASRPGSRSTQAAPKAPAAASVASTGPSSRSAPTPLPRR 1797
Cdd:PHA03307 244 SSGCGWGPENE-----------CPLPRPAPITLPTRIWEAsGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1798 PAGTKTEGKPADAKKAVTKSAPADLSRAKSTSSSTARKTAAGPGPGSPAGAAPSRVKPTPVSPRASGTLAVDKKPTSARP 1877
Cdd:PHA03307 313 RASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARA 392
|
410
....*....|....*.
gi 987959268 1878 SSLAPRLSRPATSAST 1893
Cdd:PHA03307 393 AVAGRARRRDATGRFP 408
|
|
| Tubulin-binding |
pfam00418 |
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
1895-1916 |
5.23e-07 |
|
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.
Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 47.41 E-value: 5.23e-07
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
349-771 |
9.01e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 54.22 E-value: 9.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 349 EREMALAKDTASPTAkelALSSGTEVAPVKGMAPPPETEVAPGkdmAPPPETEGLGMAPPPETEVAPVKGMAPPPETEVA 428
Cdd:PRK07764 382 ERRLGVAGGAGAPAA---AAPSAAAAAPAAAPAPAAAAPAAAA---APAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPS 455
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 429 PVKGMAPPPEIEVASVKGMAPPPETEVVPVKGMAPPPETEVVPVKGVAPPPETEVTPGKDVPLLPE--PEPSLAKDVVPP 506
Cdd:PRK07764 456 PPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERWPEILAavPKRSRKTWAILL 535
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 507 SETEVAPVpakdMGTVRTPGKPSEGPQ--FASLRNE-----------GPSAVPAAVASPEPVtAVGQTSALPPDEASVPE 573
Cdd:PRK07764 536 PEATVLGV----RGDTLVLGFSTGGLArrFASPGNAevlvtalaeelGGDWQVEAVVGPAPG-AAGGEGPPAPASSGPPE 610
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 574 KLEQRQPLSRQPPEPPAAPSGTLPTPAKQVCRPRDRRAARPRPARVPPELLGGSSPKTLDPGLGPCSVLEPGWVSGSVPC 653
Cdd:PRK07764 611 EAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAP 690
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 654 GEPGSQRKTTPAAFPETQREPGR-QAWEAESTAMMKKKKKRPKQKRCSPPRGGGPWGDDSAREADGRPVAADPQKPGVRP 732
Cdd:PRK07764 691 AAPAGAAPAQPAPAPAATPPAGQaDDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAP 770
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 987959268 733 SQPATVGGQHAP--ASRESPEEDGGVDAGTAKPAAESLVSE 771
Cdd:PRK07764 771 AAAPPPSPPSEEeeMAEDDAPSMDDEDRRDAEEVAMELLEE 811
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
387-910 |
1.19e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 54.17 E-value: 1.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 387 EVAPGKDMAPPPETEGLGMAPPPETEVAPVKGMAPPPEtevAPVKGMAPPPEIEVASVKGMAP--PPETEVVPVKGMAPP 464
Cdd:PHA03247 2542 ELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSE---PAVTSRARRPDAPPQSARPRAPvdDRGDPRGPAPPSPLP 2618
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 465 PETEVVPVKGVAPPPETEVTPGKDVPLLPEPE----PSLAKDVVPPSETEVAPVPAKDMGTVRTPGKPSEGPQFASLRNE 540
Cdd:PHA03247 2619 PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPErprdDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSL 2698
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 541 GPSAVPAAVASPEPVTAVGQTSALPpdeasVPEKLEQRQPLSRQPPEPPAAPSGTLpTPAKQVCRPRDRRAARPRPARVP 620
Cdd:PHA03247 2699 ADPPPPPPTPEPAPHALVSATPLPP-----GPAAARQASPALPAAPAPPAVPAGPA-TPGGPARPARPPTTAGPPAPAPP 2772
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 621 PELLGGSSPKTLDPGLGPCSVLEPGWVSGSVPCGEPGSQrkTTPAAFPETQREPGRQAWEAESTAMMKKKKKRPKQKRCS 700
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV--LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL 2850
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 701 PPRGGGPWGDDSAREADGRPVAADPQKPgvrpsqpatvggQHAPASRespeedggvdagTAKPAAeSLVSESPRVPSCPW 780
Cdd:PHA03247 2851 PLGGSVAPGGDVRRRPPSRSPAAKPAAP------------ARPPVRR------------LARPAV-SRSTESFALPPDQP 2905
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 781 EEPPKAAVNSQPKLSREAEVkgnKSEPQSQDReslQQGGCKPQTAPHLATPLRPEGSlpevsaHKIEAPWEVRAQEGCFP 860
Cdd:PHA03247 2906 ERPPQPQAPPPPQPQPQPPP---PPQPQPPPP---PPPRPQPPLAPTTDPAGAGEPS------GAVPQPWLGALVPGRVA 2973
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 987959268 861 VSDQEAPGPvVKPTAAKELPNPTRTLTANNPLES-----SLKEGSDGRTVPALQT 910
Cdd:PHA03247 2974 VPRFRVPQP-APSREAPASSTPPLTGHSLSRVSSwasslALHEETDPPPVSLKQT 3027
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
379-750 |
2.46e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 53.02 E-value: 2.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 379 GMAPPPETEVAPGKDMAPPPeteglgmAPPPETEVAPVKGMAPPPETEVAPVKGMAPPPEIEVASvkgmaPPPETEVVPV 458
Cdd:PHA03247 2590 DAPPQSARPRAPVDDRGDPR-------GPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP-----PPERPRDDPA 2657
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 459 KGMAPPPETEVVPVKgvaPPPETEVTPGKDVPLLPEPEPSLAKDVVPPSEtEVAPVPAKDMGTVRTPGKPseGPQFASLR 538
Cdd:PHA03247 2658 PGRVSRPRRARRLGR---AAQASSPPQRPRRRAARPTVGSLTSLADPPPP-PPTPEPAPHALVSATPLPP--GPAAARQA 2731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 539 NEGPSAVPAAVASPE-PVTAVGQTS-ALPPDEASVPEKLEQRQPLSRQPPEPPAAPSGTLPTPAKQVCRPRDRRAARPRP 616
Cdd:PHA03247 2732 SPALPAAPAPPAVPAgPATPGGPARpARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV 2811
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 617 ARVPPELLGGSSPKTLD----------PGLGPCSVLEPGWVSGSVPCGEPGSQRKTT--PAAFPETQREPGRQAWEAEST 684
Cdd:PHA03247 2812 LAPAAALPPAASPAGPLppptsaqptaPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSrsPAAKPAAPARPPVRRLARPAV 2891
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 987959268 685 AMMKKKKKRPKQKRCSPPRGGGPWGDDSAREADGRPVAADPQKPGVRPSQPATVGGQHAPASRESP 750
Cdd:PHA03247 2892 SRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG 2957
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1669-1894 |
3.00e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 52.57 E-value: 3.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1669 RPTKSRGLAPLSPKPAAVQERGRPEHATPSGTAKPEGPAAASVTGNDITAPPNKELPPSPEKKAKVVAGMPVAETKVPEK 1748
Cdd:PRK12323 364 RPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARG 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1749 KATPSKPASAPASRPgsrstqaapkaPAAASVASTGPSSRSAPTPLPRRPAGTKTEGKPADAKKAVTKSAPADLSRAKST 1828
Cdd:PRK12323 444 PGGAPAPAPAPAAAP-----------AAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPA 512
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 987959268 1829 SSSTARKTAAGPGPGSPAGAAPSRVKPTPVSPRASGTLAVDKKPTSARPSSLAPRLSRPATSASTP 1894
Cdd:PRK12323 513 QPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFD 578
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
379-598 |
4.48e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 51.80 E-value: 4.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 379 GMAPPPETEVAPGKDMAPPPETEGLGMAPP--PETEVAPVKGMAPPPETEVAPVKGMAPPPEIEVASVKGMAPPPETEVV 456
Cdd:PRK12323 370 GGAGPATAAAAPVAQPAPAAAAPAAAAPAPaaPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 457 PVKGMAPPPETEVVP-VKGVAPPPETEVTPgkDVPLLPEPEPSLAKDVVPPSETEVAPVPAkdmgtvrtPGKPSEGPQFA 535
Cdd:PRK12323 450 PAPAPAAAPAAAARPaAAGPRPVAAAAAAA--PARAAPAAAPAPADDDPPPWEELPPEFAS--------PAPAQPDAAPA 519
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 987959268 536 SLRNEGPSAVPAAVASPEpvtavGQTSALPPDEASVPEKLEQRQPlsRQPPEPPAAPSGTLPT 598
Cdd:PRK12323 520 GWVAESIPDPATADPDDA-----FETLAPAPAAAPAPRAAAATEP--VVAPRPPRASASGLPD 575
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
181-600 |
1.05e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 50.75 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 181 LPCDTLTPEAVVPQDWPVEApHGPQAGAFISPEATPPLQPTAEPAGERETASEERASTRASGTMLELKAADMAPSREA-E 259
Cdd:PRK07764 364 LPSASDDERGLLARLERLER-RLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPApP 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 260 TALAQDMVPATETEVALATNVASPTKEDVSFAKNMDSPIESDVAAVRDVVLP-IEAKETPAKGAVLLRDTERAPPMEMDA 338
Cdd:PRK07764 443 SPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPaAPAAPAAPAGADDAATLRERWPEILAA 522
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 339 A------------PAAGVVSLTEREMALAKDTaSPTAKELALSSGTEV-----APVKGMAPPPETEVAPGKDMAPPPETE 401
Cdd:PRK07764 523 VpkrsrktwaillPEATVLGVRGDTLVLGFST-GGLARRFASPGNAEVlvtalAEELGGDWQVEAVVGPAPGAAGGEGPP 601
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 402 GLGMAPPPETEVAPvKGMAPPPETEVAPVKGMAPPPEIEVASVKGMAPPPETEVVPVKGMAPPPETEVVPVKGVAPPPET 481
Cdd:PRK07764 602 APASSGPPEEAARP-AAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAA 680
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 482 EVTPgkdvpllPEPEPSLAKDVVPPSETEVAPVPAKdmGTVRTPGKPSEGPQFASLRNEGPSAVPAAVASPEPVTAVGQT 561
Cdd:PRK07764 681 PPPA-------PAPAAPAAPAGAAPAQPAPAPAATP--PAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDP 751
|
410 420 430
....*....|....*....|....*....|....*....
gi 987959268 562 SALPPDEASVPEKLEQRQPLSRQPPEPPAAPSGTLPTPA 600
Cdd:PRK07764 752 AGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDA 790
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
355-569 |
1.42e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 50.26 E-value: 1.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 355 AKDTASPTAKELALSSGTEVAPVKGMAPPPETEVAPGKDMAPPPETEGLG-MAPPPETEVAPVKGMAPPPETEVAPVKGM 433
Cdd:PRK12323 375 ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPArRSPAPEALAAARQASARGPGGAPAPAPAP 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 434 APPPeievasvKGMAPPPETEVVPVKGMAPPPETEVVPVKGVAPPPEtevtpgkDVPLLPEPEPSLAkdVVPPSETEVAP 513
Cdd:PRK12323 455 AAAP-------AAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADD-------DPPPWEELPPEFA--SPAPAQPDAAP 518
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 987959268 514 VPAKDMGTVRtPGKPSEGPQFASLRnEGPSAVPAAVASPEPVTAVGQTsalPPDEA 569
Cdd:PRK12323 519 AGWVAESIPD-PATADPDDAFETLA-PAPAAAPAPRAAAATEPVVAPR---PPRAS 569
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
352-507 |
4.31e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 48.71 E-value: 4.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 352 MALAKDTASPTAKELALSSGTEVAPVKGMAPPPETEVAPGKDMAPPPETEGLGMAPPPETEVAPVKGMAPPPETEVAPVK 431
Cdd:PRK07994 363 APLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSE 442
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 987959268 432 GMAPPPEIEVASVKGMAPPPETEVVPVKGMAPPPET-EVVPVKGVAPPPETEVTPGK-DVPLLPEPEPSLAKDVVPPS 507
Cdd:PRK07994 443 PAAASRARPVNSALERLASVRPAPSALEKAPAKKEAyRWKATNPVEVKKEPVATPKAlKKALEHEKTPELAAKLAAEA 520
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
408-593 |
4.82e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 48.69 E-value: 4.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 408 PPETEVAPVKGMAPPPETEVAPVKGMAPPPEIEVASVKGMAPP---PETEVVPVKGMAPPPETEVVPVKGVAPPPETEVT 484
Cdd:PRK07003 360 PAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVtgaAGAALAPKAAAAAAATRAEAPPAAPAPPATADRG 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 485 PGKDVPLLPEPEPSLAKDVVPPSETEVAPVPAKDMGTVRTPgkPSEGPQFASLRNEGPSAVPAAVASPEPVTAVGQTSAL 564
Cdd:PRK07003 440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAP--ASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAS 517
|
170 180
....*....|....*....|....*....
gi 987959268 565 PPDEASVPEkleqrQPLSRQPPEPPAAPS 593
Cdd:PRK07003 518 REDAPAAAA-----PPAPEARPPTPAAAA 541
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
374-514 |
6.03e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 48.17 E-value: 6.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 374 VAPVKGMAPPPETEVAPgkdmAPPPETeglgmaPPPETEVAPVKGMAPPPeteVAPVKGMAPPPEIEVASVkgmAPPPET 453
Cdd:PRK14951 375 PAEKKTPARPEAAAPAA----APVAQA------AAAPAPAAAPAAAASAP---AAPPAAAPPAPVAAPAAA---APAAAP 438
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 987959268 454 EVVPVKGMAPPPETEVVPVKGVAPPPETEVTPGKDVpllPEPEPSLAKDVVPPSETEVAPV 514
Cdd:PRK14951 439 AAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVAS---AAPAPAAAPAAARLTPTEEGDV 496
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
355-488 |
7.72e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 47.79 E-value: 7.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 355 AKDTASPTAKELALSSGTEVAPvkgmAPPPETEVAPGkdMAPPPETEglgMAPPPETEVAPVKGMAPPPETEVAPVKGMA 434
Cdd:PRK14951 370 AEAAAPAEKKTPARPEAAAPAA----APVAQAAAAPA--PAAAPAAA---ASAPAAPPAAAPPAPVAAPAAAAPAAAPAA 440
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 987959268 435 PPPEIEVASVKGMAPPPETEVVPVKgMAPPPETEVVPVKGVAPPPETEVTPGKD 488
Cdd:PRK14951 441 APAAVALAPAPPAQAAPETVAIPVR-VAPEPAVASAAPAPAAAPAAARLTPTEE 493
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
303-519 |
1.33e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 47.18 E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 303 AAVRDVVLPIEAKETPAKGAVLLRDTERAPPMEMDAAPAAGVVSLTEREMALAKDTASPTAKELALSSGTEVAPVKGMAP 382
Cdd:PRK12323 377 AAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAA 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 383 PPETEVAPGKDMAPPPETEGLGMAPPPETEVAPVKGMAPPPETEVAPVKGMAPPPEIEVASVKGMAPPPETEVVPVKGMA 462
Cdd:PRK12323 457 APAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDD 536
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 987959268 463 PPPETEVVPVKGVAPPPETEVTpgkdvPLLPEPEPSLAKDVVPPSETEVAPVPAKDM 519
Cdd:PRK12323 537 AFETLAPAPAAAPAPRAAAATE-----PVVAPRPPRASASGLPDMFDGDWPALAARL 588
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
493-602 |
1.65e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 46.63 E-value: 1.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 493 PEPEPSLAKDVVPPSETEVAPVPAKDMGTVRTPGKP-----SEGPQFASLRNEGPSAVPAAVAsPEPVTAVGQTSALPPD 567
Cdd:PRK14951 371 EAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAApaaaaSAPAAPPAAAPPAPVAAPAAAA-PAAAPAAAPAAVALAP 449
|
90 100 110
....*....|....*....|....*....|....*
gi 987959268 568 EASVPEKLEQRQPLSRQPPEPPAAPSGTLPTPAKQ 602
Cdd:PRK14951 450 APPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPA 484
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1669-1861 |
1.81e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.90 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1669 RPTKSRGLAPLSPKPAAVQERGRPEHATPSGTAKPEGPAAASVTGNDITAPPNKELPPSPEKKAKVVAGMPVAETkvpek 1748
Cdd:PRK07764 601 PAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGG----- 675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1749 kATPSKPASAPASRPGSRSTQAAPKAPAAASVASTGPSSRSAPTPLPRRPAGTKTEGKPADAKKAVTKSAPADLSRAKST 1828
Cdd:PRK07764 676 -AAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGA 754
|
170 180 190
....*....|....*....|....*....|...
gi 987959268 1829 SSSTARKTAAGPGPGSPAGAAPSRVKPTPVSPR 1861
Cdd:PRK07764 755 PAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAE 787
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
421-738 |
2.26e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 46.68 E-value: 2.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 421 PPPETEVAPVKGMAPPPEIEVASVKGMAPPPETEVVPVKGMAPPPETEVVPVKGVAPPPETEVTPGKDVPLLPEPEPSLA 500
Cdd:pfam03154 171 PPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQ 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 501 KDVVPPSETEVAPVPakdmgtVRTPGKPSEGPQFASLRNEGPSAVPAAVAS----PEPVTAVGQTSALPPDEASVPEKLE 576
Cdd:pfam03154 251 PMTQPPPPSQVSPQP------LPQPSLHGQMPPMPHSLQTGPSHMQHPVPPqpfpLTPQSSQSQVPPGPSPAAPGQSQQR 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 577 QRQPLSR------QPPEPPAAPSGTLPTPAKQVCRPRDRRAARPRPARVPPELLGGSSPKTLDPGLGPCSVLEPgwvSGS 650
Cdd:pfam03154 325 IHTPPSQsqlqsqQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKP---LSS 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 651 VPCGEPGSQRKTTPAAFPETQREPGRQAWEAESTAMMKKKKKRPKQKRCS-----------PPRGGGPWGDDSAREADGR 719
Cdd:pfam03154 402 LSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSglhqvpsqspfPQHPFVPGGPPPITPPSGP 481
|
330
....*....|....*....
gi 987959268 720 PVAADPQKPGVRPSQPATV 738
Cdd:pfam03154 482 PTSTSSAMPGIQPPSSASV 500
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
331-538 |
3.23e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 46.02 E-value: 3.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 331 APPMEMDAAPAAGVVSLTEREMALAKDTASPTAKELALSSGTEVAPVKGMAPPPETEVAPGKDMAPPPETEGLGMAPPPE 410
Cdd:PRK12323 372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 411 TEVAPVK-GMAPPPETEVAPVKGMAPPPEIEVASVKGMAPPPEtevvpvkgmAPPPETEVVPVKGVAPPPETEVTP-GKD 488
Cdd:PRK12323 452 PAPAAAPaAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADD---------DPPPWEELPPEFASPAPAQPDAAPaGWV 522
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 987959268 489 VPLLPEPEPSLAKDVVPPSETEVAPVPAKDMGTVRTPGKPSEGPQFASLR 538
Cdd:PRK12323 523 AESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASG 572
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
248-566 |
3.77e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 45.61 E-value: 3.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 248 KAADMAPSREAETALAQDMVPATETEVALATNVASPTKEDVSFAKNMDSPIESDVAAVRDVVLPIEAKETPAKGAVLLRD 327
Cdd:PRK07003 378 GAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARA 457
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 328 TERAPPMEMDAAPAAGVVSlterEMALAKDTASPTAKELALSSGTEVAPVKGMAPPPETEVAPGKDMAPPPETEGLGMAP 407
Cdd:PRK07003 458 SADSRCDERDAQPPADSGS----ASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEAR 533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 408 PPEtevaPVKGMAPPPETEVAPVKGMAPPPEIEVASVKGMAPPPETEVVPVKGMAPPPETEVVPVKGVAPPPETEVTPGK 487
Cdd:PRK07003 534 PPT----PAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAP 609
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 488 DVPLLPEPEPSLAKDVVPPSE----TEVAPVPAKDMGtvrtpGKPSEGpqFASLRNEGPSAVPAAVASPEPVTAVGQTSA 563
Cdd:PRK07003 610 PNGAARAEQAAESRGAPPPWEdippDDYVPLSADEGF-----GGPDDG--FVPVFDSGPDDVRVAPKPADAPAPPVDTRP 682
|
...
gi 987959268 564 LPP 566
Cdd:PRK07003 683 LPP 685
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
1558-1885 |
4.27e-04 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 45.76 E-value: 4.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1558 NKEMEMTLSTPKSEQDKREGSSLAPKITESADaplpapalqsdffngqlGAAPSSAVEKLAVTacqglplpePEEKASEA 1637
Cdd:TIGR00927 69 NDEMMMVSSDPPKSSSEMEGEMLAPQATVGRD-----------------EATPSIAMENTPSP---------PRRTAKIT 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1638 PEKMTEKPEPKALGEGKKEEKRAAEPLK--GYMRPTKSRGLA-PLSPKP-------AAVQERGRPEHATPSGTAKPEGPA 1707
Cdd:TIGR00927 123 PTTPKNNYSPTAAGTERVKEDTPATPSRalNHYISTSGRQRVkSYTPKPrgevkssSPTQTREKVRKYTPSPLGRMVNSY 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1708 AASVTgndITAPPNKELPP-SPEKKAKVVAGMPVAETK-----------VPEKKATPSKPA-----------SAPASRPG 1764
Cdd:TIGR00927 203 APSTF---MTMPRSHGITPrTTVKDSEITATYKMLETNpskrtagkttpTPLKGMTDNTPTfltrevetdllTSPRSVVE 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1765 SRSTQAAPKAPAAASVASTGPSSRSAPTPlprrPAGTKTEGKPADAKKAVTKSAPADLSRAKsTSSSTARKTAAGPGPGS 1844
Cdd:TIGR00927 280 KNTLTTPRRVESNSSTNHWGLVGKNNLTT----PQGTVLEHTPATSEGQVTISIMTGSSPAE-TKASTAAWKIRNPLSRT 354
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1845 PAGAA-------------PSRVKPTPVSP--RASGTLAVDK----KPTSARPSSLAPRLS 1885
Cdd:TIGR00927 355 SAPAVriasatfrgleknPSTAPSTPATPrvRAVLTTQVHHcvvvKPAPAVPTTPSPSLT 414
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
503-880 |
4.79e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 4.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 503 VVPPSETEVAPVPAKDMGTVRTPGKPSEGPQFASLRNEGPSAVPAAVASPEPVTAVGQTSALPPDEASVPEKLEQRQPLS 582
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQ 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 583 RQPPEPPAAPSGTLPTPAKQVCRPRDRRAARPRPARVPP----------------ELLGGSSPKTLDPGLGPCSVLEPG- 645
Cdd:PRK07764 466 PAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAgaddaatlrerwpeilAAVPKRSRKTWAILLPEATVLGVRg 545
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 646 ---WVSGSVPC-----GEPGSQRKTTPAAFPETQREPGRQAWEAESTAMMKKKKKRPKQKRCSP-----PRGGGPWGDDS 712
Cdd:PRK07764 546 dtlVLGFSTGGlarrfASPGNAEVLVTALAEELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPPeeaarPAAPAAPAAPA 625
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 713 AREADGRPVAADPQKPGVRPSQPAtvgGQHAPASRESPEEDGGVDAGTAKPAAESLVSESPRVPSCPWEEPPKAAVNSQP 792
Cdd:PRK07764 626 APAPAGAAAAPAEASAAPAPGVAA---PEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA 702
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 793 KLSREAEVKGNKSEPQSQDReSLQQGGCKPQTAPHLATPLRPEGSLPEVSAHkieAPWEVRAQEGCFPVSDQEAPGPVVK 872
Cdd:PRK07764 703 PAPAATPPAGQADDPAAQPP-QAAQGASAPSPAADDPVPLPPEPDDPPDPAG---APAQPPPPPAPAPAAAPAAAPPPSP 778
|
....*...
gi 987959268 873 PTAAKELP 880
Cdd:PRK07764 779 PSEEEEMA 786
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
331-599 |
5.86e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 45.23 E-value: 5.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 331 APPMEMDAAPAAGVVSLTEREMALAKDTASPTAKELALSSGTEVAPVKGMAPPPETEVAPGKDMAPPPeTEGLGMAPPPE 410
Cdd:PRK07003 367 APGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPA-TADRGDDAADG 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 411 TEVAPVKGMAPPPETEVAPVKGMAPPPEIEVASVKGMAPPPETevvpvkgmAPPPETEVVPVKGVAPPPETEVTPGKDVP 490
Cdd:PRK07003 446 DAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDA--------AFEPAPRAAAPSAATPAAVPDARAPAAAS 517
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 491 LLPEPEPSlakdvVPPSETEVAPVPAKDMGTVRTPGKPSegpQFASLRNEG------PSAVPAAVASPEPVTAVGQTSAL 564
Cdd:PRK07003 518 REDAPAAA-----APPAPEARPPTPAAAAPAARAGGAAA---ALDVLRNAGmrvssdRGARAAAAAKPAAAPAAAPKPAA 589
|
250 260 270
....*....|....*....|....*....|....*....
gi 987959268 565 PPDEASVP----EKLEQRQPLSRQPPEPPAAPSGTLPTP 599
Cdd:PRK07003 590 PRVAVQVPtpraRAATGDAPPNGAARAEQAAESRGAPPP 628
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
187-553 |
6.12e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 44.98 E-value: 6.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 187 TPEAVVPQDWPVEAPHGPQAGAFISPEATPPLQPTAEPAGERETASEERASTRA-SGTMLELKAADMAPSREAETAL--- 262
Cdd:PRK07764 443 SPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAApAAPAAPAGADDAATLRERWPEIlaa 522
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 263 AQDMVPATETEVALATNVASPTKEDVSF-------AKNMDSPIESDV--AAVRDVV---LPIEAKETPAKGAVLLRDTE- 329
Cdd:PRK07764 523 VPKRSRKTWAILLPEATVLGVRGDTLVLgfstgglARRFASPGNAEVlvTALAEELggdWQVEAVVGPAPGAAGGEGPPa 602
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 330 --RAPPMEMDAAPAAGVVSlteremalAKDTASPTAKELALSSGTEVAPVKGMAPPPetevAPGKDMAPPPETEGLGMAP 407
Cdd:PRK07764 603 paSSGPPEEAARPAAPAAP--------AAPAAPAPAGAAAAPAEASAAPAPGVAAPE----HHPKHVAVPDASDGGDGWP 670
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 408 PPETEVAPVKGMAPPPETEVAPVKGMAPPPEievasvkgmAPPPETEVVPVKGMAPPPETEVVPVKGVAPPPETEVtpgk 487
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQP---------APAPAATPPAGQADDPAAQPPQAAQGASAPSPAADD---- 737
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 987959268 488 DVPLLPEPEPSLAKDVVPPSETEVAPVPAKDmGTVRTPGKPSEGPQFASLRNEGPSAVPAAVASPE 553
Cdd:PRK07764 738 PVPLPPEPDDPPDPAGAPAQPPPPPAPAPAA-APAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAE 802
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
291-430 |
6.87e-04 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 44.17 E-value: 6.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 291 AKNMDSPIESDVAAVRDVVLPIEAKETPAKGAvllrdterAPPMEMDAAPAAGVVSLTEREMALAKDTASPtAKELALSS 370
Cdd:PTZ00436 223 AKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAA--------APPAKAAAPPAKAAAPPAKAAAPPAKAAAPP-AKAAAPPA 293
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 371 GTEVAPVKGMAPPPETEVAPGKDMAPPPETEglgmAPPPETEVAPVKGMAPPPETEVAPV 430
Cdd:PTZ00436 294 KAAAAPAKAAAAPAKAAAAPAKAAAPPAKAA----APPAKAATPPAKAAAPPAKAAAAPV 349
|
|
| KAR9 |
pfam08580 |
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ... |
1693-1893 |
7.80e-04 |
|
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.
Pssm-ID: 430088 [Multi-domain] Cd Length: 684 Bit Score: 44.44 E-value: 7.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1693 EHATPSGTAKPEGPAAASVT---GNDITAPPNKELPPSPEKKA---KVVAGMPVAETKVPEKKAT---PSKPASAPASRP 1763
Cdd:pfam08580 420 SPATLVANKTPGSSPPSSVImtpVNKGSKTPSSRRGSSFDFGSsseRVINSKLRRESKLPQIASTlkqTKRPSKIPRASP 499
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1764 GSRSTQAAPKAPAAASV--ASTGPSSRSAPTPLPRRPAGTKTEgKPADAKKAVTKSaPADLSRAKSTSSSTARKTAAGPG 1841
Cdd:pfam08580 500 NHSGFLSTPSNTATSETptPALRPPSRPQPPPPGNRPRWNAST-NTNDLDVGHNFK-PLTLTTPSPTPSRSSRSSSTLPP 577
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 987959268 1842 PGSPAGAAPSRVKPTPVSPRASGTLAVDKKPT-SARPSSLAPRLSRPATSAST 1893
Cdd:pfam08580 578 VSPLSRDKSRSPAPTCRSVSRASRRRASRKPTrIGSPNSRTSLLDEPPYPKLT 630
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1666-1894 |
9.33e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 44.46 E-value: 9.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1666 GYMRPTKSRGLAPLSPKPAAVQERGRPEHATPSGTAKPEGPAAASVTGNDITAPPNKELPPSPEKKAKVVAGMPVAETKV 1745
Cdd:PRK07003 370 GGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPV 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1746 PEKKATPSkpasAPASRPGSRSTQ-AAPKAPAAASVASTGPSSRSAPTPlprrPAGTKTEGKPADAKKAVTKSAPADLSR 1824
Cdd:PRK07003 450 PAKANARA----SADSRCDERDAQpPADSGSASAPASDAPPDAAFEPAP----RAAAPSAATPAAVPDARAPAAASREDA 521
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 987959268 1825 AKSTSSSTARKTAAGPGPGSPA----GAAPS----RVKPTPVSPRASGTLAVDKKPTSARPSSLAPRLSRPATSASTP 1894
Cdd:PRK07003 522 PAAAAPPAPEARPPTPAAAAPAaragGAAAAldvlRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTP 599
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
387-589 |
9.71e-04 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 44.26 E-value: 9.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 387 EVAPGK-----DMAPPPETEGLGMAPPPETEVAP--VKGMAPPPETEVAPVKGMAPPPEIEVASVKgMAPPPETEVVPVK 459
Cdd:PRK10811 835 EMASGKvwiryPVVRPQDVQVEEQREAEEVQVQPvvAEVPVAAAVEPVVSAPVVEAVAEVVEEPVV-VAEPQPEEVVVVE 913
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 460 gmAPPPETEVVPVkgVAPPPeteVTPGKDVPLLPEPEPSLAKDVVPPSETEVAPVPAKDMGTVRTPGKPSEGPQFASLRN 539
Cdd:PRK10811 914 --TTHPEVIAAPV--TEQPQ---VITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAE 986
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 987959268 540 EGPSAVPAAVASPEPVTAVGQTSALPPDEASVPeklEQRQPLSRQPPEPP 589
Cdd:PRK10811 987 VAAEVETVTAVEPEVAPAQVPEATVEHNHATAP---MTRAPAPEYVPEAP 1033
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
389-599 |
1.70e-03 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 43.22 E-value: 1.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 389 APGKDMAPPPETEGLGMAPPPETEVAPVKGMAPPPETEVapvkgmAPPPEIEVASVKGMAPPPETEV-----VPVKGMAP 463
Cdd:NF033839 294 APKPGMQPSPQPEKKEVKPEPETPKPEVKPQLEKPKPEV------KPQPEKPKPEVKPQLETPKPEVkpqpeKPKPEVKP 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 464 PPETevvPVKGVAPPPETEVTPGKDVPLLPEPEPSLAKDVVPPSETEVAPVPAKDMGTVRTPGKPSEGPQFASlrnegps 543
Cdd:NF033839 368 QPEK---PKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEK------- 437
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 987959268 544 avPAAVASPEPVTAvgqtsalPPDEASVPEKLEQRQPLSRQPPEPPAAPSGTLPTP 599
Cdd:NF033839 438 --PKPEVKPQPEKP-------KPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKP 484
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1741-1865 |
2.38e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.78 E-value: 2.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1741 AETKVPEKKATPSKP-ASAPASRPGSRSTQAAPKAPAAasvastgPSSRSAPTPLPRRPAGTKTEGKPADAKKAVTKSAP 1819
Cdd:PRK14951 370 AEAAAPAEKKTPARPeAAAPAAAPVAQAAAAPAPAAAP-------AAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAP 442
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 987959268 1820 ADLSRAKSTSSSTARKTAAGP------------GPGSPAGAAPSRVKPTPVSPRASGT 1865
Cdd:PRK14951 443 AAVALAPAPPAQAAPETVAIPvrvapepavasaAPAPAAAPAAARLTPTEEGDVWHAT 500
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
462-603 |
2.59e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.93 E-value: 2.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 462 APPPETEVVPVKGVAPPPETEVTPGKDVPLLPEPEPSlakdvvPPSETEVAPVPAkdmgtvrTPGKPSEGPQFASLRN-- 539
Cdd:PRK07994 370 VPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASA------PQQAPAVPLPET-------TSQLLAARQQLQRAQGat 436
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 987959268 540 EGPSAVPAAVASPEPVTAVGQTSALPPDEASVPEKLEQRQPLSR---QPPEPPAAPSGTLPTPAKQV 603
Cdd:PRK07994 437 KAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRwkaTNPVEVKKEPVATPKALKKA 503
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
462-600 |
2.75e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.78 E-value: 2.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 462 APPPETEVVPVKGVAPPPETEVTPGKDVPLLPEPEPSLAKDVVPPSETEVAPVPAKDMGTVRTPGKPSEGPQFASlrneg 541
Cdd:PRK14951 372 AAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVA----- 446
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 987959268 542 PSAVPAAVASPEPVtavgqtsalppdeaSVPEKLEQRQPLSRQPPEPPAAPSGTLPTPA 600
Cdd:PRK14951 447 LAPAPPAQAAPETV--------------AIPVRVAPEPAVASAAPAPAAAPAAARLTPT 491
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
1456-1851 |
3.06e-03 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 42.45 E-value: 3.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1456 GESESGPRGASKRPAEEITEPAKGPRPAVPTADQSPRPErggpgvrAGGSPVPASPVNREGEAGAGSASSHTADFPGDGP 1535
Cdd:NF033839 146 DSSSSSSSGSSTKPETPQPENPEHQKPTTPAPDTKPSPQ-------PEGKKPSVPDINQEKEKAKLAVATYMSKILDDIQ 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1536 QKPLCCEDQHAEGGASRGPTGLNKEMEMTLSTPKSeqdKREGSSLAPKITESADAPLpapalqSDFFNGQLGAAPSSAVE 1615
Cdd:NF033839 219 KHHLQKEKHRQIVALIKELDELKKQALSEIDNVNT---KVEIENTVHKIFADMDAVV------TKFKKGLTQDTPKEPGN 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1616 KLAVTACQGL-PLPEPEEKASEA----------PEKMTEKPEPKALGEGKKEE-KRAAEPLKGYMRPTKSRGLAPLSPKP 1683
Cdd:NF033839 290 KKPSAPKPGMqPSPQPEKKEVKPepetpkpevkPQLEKPKPEVKPQPEKPKPEvKPQLETPKPEVKPQPEKPKPEVKPQP 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1684 AAVQERGRPEHATPSGTAKPEgPAAASVTGNDITAPPNKELPPSPEKKAKVVAgmPVAETKVPEKKATPSKPASAPASRP 1763
Cdd:NF033839 370 EKPKPEVKPQPETPKPEVKPQ-PEKPKPEVKPQPEKPKPEVKPQPEKPKPEVK--PQPEKPKPEVKPQPEKPKPEVKPQP 446
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1764 GSRSTQAAPKAPAAASVASTGPSS-RSAPTPLPRRPAGTKTEGKPADAKKAVTKSAPADlsRAKSTSSSTARKTAAGPGP 1842
Cdd:NF033839 447 EKPKPEVKPQPETPKPEVKPQPEKpKPEVKPQPEKPKPDNSKPQADDKKPSTPNNLSKD--KQPSNQASTNEKATNKPKK 524
|
....*....
gi 987959268 1843 GSPAGAAPS 1851
Cdd:NF033839 525 SLPSTGSIS 533
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
406-576 |
3.12e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.55 E-value: 3.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 406 APPPETEVAPVKGMAPPPETeVAPVKGMAPPPEIEVASVKGMAPPPETEVVPVKGMAPPPE--TEVVPVKGVAPPPETE- 482
Cdd:PRK07994 365 LPEPEVPPQSAAPAASAQAT-AAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAarQQLQRAQGATKAKKSEp 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 483 VTPGKDVPLLPEPEPSLAkdvVPPSETEVAPVPAKDMGTVRTPGKPSEGPQFASLRnegPSAVPAAVA---SPEPVTAVG 559
Cdd:PRK07994 444 AAASRARPVNSALERLAS---VRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVAT---PKALKKALEhekTPELAAKLA 517
|
170
....*....|....*..
gi 987959268 560 QTSALPPDEASVPEKLE 576
Cdd:PRK07994 518 AEAIERDPWAALVSQLG 534
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1593-1876 |
3.24e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 42.53 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1593 PAPALQSDFFNGQLGAAPSSAVEKLAVTACQGLPLPEPEEKASEAPEKMTEKPEPKALGEGKKEEKRAAEPLKGYMRPTK 1672
Cdd:PRK07003 360 PAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRG 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1673 SRGLAPLSPKPAAVQERGRPEHATPSGTAKPEGPAAASVTGNDITAPPNKELPPSPEKKAKVVAGMPVAETKVPEKKATP 1752
Cdd:PRK07003 440 DDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASRE 519
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1753 SKPasAPASRPGSRSTqaapkapaaasvastgpssrsAPTPLPRRPAgtkTEGKPADAKKAVTKSAPADLSRAKSTSSST 1832
Cdd:PRK07003 520 DAP--AAAAPPAPEAR---------------------PPTPAAAAPA---ARAGGAAAALDVLRNAGMRVSSDRGARAAA 573
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 987959268 1833 ARKTAAGPgPGSPAGAAPSRVKPTPvSPRASGTLAVDKKPTSAR 1876
Cdd:PRK07003 574 AAKPAAAP-AAAPKPAAPRVAVQVP-TPRARAATGDAPPNGAAR 615
|
|
| PRK10819 |
PRK10819 |
transport protein TonB; Provisional |
405-541 |
3.41e-03 |
|
transport protein TonB; Provisional
Pssm-ID: 236768 [Multi-domain] Cd Length: 246 Bit Score: 41.59 E-value: 3.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 405 MAPPPETEVAPVKGMAPPPETEVAPvkgmaPPPEIEVASVKGMAPPPEtevvpvkgmaPPPETEVVPVKGVAPPPETEVT 484
Cdd:PRK10819 58 LEPPQAVQPPPEPVVEPEPEPEPIP-----EPPKEAPVVIPKPEPKPK----------PKPKPKPKPVKKVEEQPKREVK 122
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 987959268 485 PGKDVPLLPEPEPSLAKDV-VPPSETEVAPVPAKDMG-TVRTPGKPSEGPQFASLRNEG 541
Cdd:PRK10819 123 PVEPRPASPFENTAPARPTsSTATAAASKPVTSVSSGpRALSRNQPQYPARAQALRIEG 181
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
372-516 |
3.47e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 42.72 E-value: 3.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 372 TEVAPVKGMAPPPETEVAPGKDMAPPPETEGLGMAPPPETEVAPVKgmAPPPETEVAPVKgmAPPPEI---------EVA 442
Cdd:PRK10811 868 PVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVE--TTHPEVIAAPVT--EQPQVItesdvavaqEVA 943
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 987959268 443 SVKGMAPPPETEVVPVKGMAPPPETEVVPVKGVAPPPETEVtpgkdvpllPEPEPSLAKDVVPPSETEVAPVPA 516
Cdd:PRK10811 944 EHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVV---------AEVAAEVETVTAVEPEVAPAQVPE 1008
|
|
| SOG2 |
pfam10428 |
RAM signalling pathway protein; SOG2 proteins in Saccharomyces cerevisiae are involved in cell ... |
1745-1907 |
3.95e-03 |
|
RAM signalling pathway protein; SOG2 proteins in Saccharomyces cerevisiae are involved in cell separation and cytokinesis.
Pssm-ID: 431280 Cd Length: 476 Bit Score: 42.01 E-value: 3.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1745 VPEKKATPSKPASAPASRPGSRSTQAAPKAPAAASVASTGPSSRSAPTPLPR-RPAGT-KTEGKPADAKKAVTKSAPADL 1822
Cdd:pfam10428 153 GPLLEAVRPPSPKKRAGRTKQPSPSITSGGSPSSPAESSTRPSSSSVTPTRRrRHAGSfSSKLPPLRSDTTIPHPGGNLS 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1823 SRAKSTSSSTARKTAAG----PGPGSPAGAAPSRVKPTPV------------SPRASGTLAVDKKPTSARPSSLApRLSR 1886
Cdd:pfam10428 233 SPAPNGAQTPTPPRSATspgvPSSAPTLGTGSTGAISRSNhstsgsqssltsSSRSRSSSRSNTLLSTSGPSSLA-TTPR 311
|
170 180
....*....|....*....|.
gi 987959268 1887 PATSASTPDLKNVRAKVGSTE 1907
Cdd:pfam10428 312 PSSGESFAPTSTGSRINPLTG 332
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
152-401 |
4.23e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.17 E-value: 4.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 152 LLFFPSGAHGASALTRQSDPlrdrdshghlPCDTLTPEAVVPQDwPVEAPHGPQAGAFISPEATPPLQPTAEPAGERETA 231
Cdd:PRK12323 361 LAFRPGQSGGGAGPATAAAA----------PVAQPAPAAAAPAA-AAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPA 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 232 SEERASTRASGTMLELKAADMAPSREAETALAQDMVPATETEVALATNVASPTKEDVSFAknmdspiesdvAAVRDVVLP 311
Cdd:PRK12323 430 PEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAP-----------APADDDPPP 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 312 IEakETPAKGAVllrdterAPPMEMDAAPAAGVVSLTEREMALAKDTASPTAKElalssgtevAPVKGMAPPPETEVAPG 391
Cdd:PRK12323 499 WE--ELPPEFAS-------PAPAQPDAAPAGWVAESIPDPATADPDDAFETLAP---------APAAAPAPRAAAATEPV 560
|
250
....*....|
gi 987959268 392 KDMAPPPETE 401
Cdd:PRK12323 561 VAPRPPRASA 570
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1608-1818 |
5.09e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.79 E-value: 5.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1608 AAPSSAVEKLAVTACQGLPLPEPEEKASEAPEKMTEKPEPKALGEGKKEEKRAAEPLKGYMRPTKSRGLAPLSPKPAAVq 1687
Cdd:PRK12323 379 AAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAA- 457
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1688 ergrPEHATPSGTAKPEGPAAAsvtgnDITAPPnkelPPSPEKKAKVVAGMPVAETKVPEKKATPSKPASAPASRPG-SR 1766
Cdd:PRK12323 458 ----PAAAARPAAAGPRPVAAA-----AAAAPA----RAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWvAE 524
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 987959268 1767 STQAAPKAPAAASVASTGPSSRSAPTPLPRRPAGTKTEGKPADAKKAVTKSA 1818
Cdd:PRK12323 525 SIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDM 576
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
381-666 |
5.59e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.06 E-value: 5.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 381 APPPETEVAPGKDMAPPPETEGLGMAPPPETEVAPVKGMAPPPETEVAPVKGMAPPPEIEV--ASVKGMAPPPETEVVPV 458
Cdd:pfam03154 184 PSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSphPPLQPMTQPPPPSQVSP 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 459 KGMAPPPETEVVPvkgVAPPPETEVTPGKDVPLLPEP---EPSLAKDVVPPSETEVAPVPAKDMGTVRTPGKPSEGPQFA 535
Cdd:pfam03154 264 QPLPQPSLHGQMP---PMPHSLQTGPSHMQHPVPPQPfplTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPP 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 536 SLRNEGPSAVPAAVASPEPVTAVGQ---------------------TSALPPDEASVP-----------------EKLEQ 577
Cdd:pfam03154 341 REQPLPPAPLSMPHIKPPPTTPIPQlpnpqshkhpphlsgpspfqmNSNLPPPPALKPlsslsthhppsahppplQLMPQ 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 578 RQPLSRQPPEPPA-APSGTLPTPAKQVCRPRDRRAARPRPARVPPELLGGSSPKTLDPgLGPCSVLEPGWVSGSVPCGEP 656
Cdd:pfam03154 421 SQQLPPPPAQPPVlTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPP-SGPPTSTSSAMPGIQPPSSAS 499
|
330
....*....|
gi 987959268 657 GSQRKTTPAA 666
Cdd:pfam03154 500 VSSSGPVPAA 509
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
326-600 |
7.32e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 41.70 E-value: 7.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 326 RDTERAPPMEMDAAPAAGVVSLTEREMALAKDTASPTAKELALSSGTEVAPVKGMAPPPETEVAPGKDmAPPPETEGLGM 405
Cdd:PHA03307 59 AAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASP-PPSPAPDLSEM 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 406 APPPETEVAPVKGMAPPPETEVAPVKGMAPPPEiEVASVKGMAPPPETEVVPVKGMAPP--------PETEVVPVKGVAP 477
Cdd:PHA03307 138 LRPVGSPGPPPAASPPAAGASPAAVASDAASSR-QAALPLSSPEETARAPSSPPAEPPPstppaaasPRPPRRSSPISAS 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 478 PPETEVTPGKDVPLLPEPEPSLAKDVVPP----SETEVAPVPAKDMGTV------------RTPGKPSEGPQfASLRNEG 541
Cdd:PHA03307 217 ASSPAPAPGRSAADDAGASSSDSSSSESSgcgwGPENECPLPRPAPITLptriweasgwngPSSRPGPASSS-SSPRERS 295
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 987959268 542 PSAVPAAVASPEPVTAVGQTSALPPDEASVPEKLEQRQPLSRQPPEPPAAPSGTLPTPA 600
Cdd:PHA03307 296 PSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPS 354
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
418-633 |
7.65e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.40 E-value: 7.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 418 GMAPPPETEVAPVKGMAPPPEIEVASVKGMAPPPETEVVPVKGMAPPPETEVVPVKgVAPPPETEVTPGKDVPLLPEPEP 497
Cdd:PRK12323 370 GGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPAR-RSPAPEALAAARQASARGPGGAP 448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 498 SLAKDVVPpsetevAPVPAKDMGTVRTPGKPSEGPQFASLRNEGPSAVPAAVASPEPVTAVGQTSALPPDEASVPEKLEQ 577
Cdd:PRK12323 449 APAPAPAA------APAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWV 522
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 987959268 578 RQPLSRQPPEPPAAPSGTLPTPAKQVCRPRDRRAARPRPARVPPELLGGSSPKTLD 633
Cdd:PRK12323 523 AESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFD 578
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
330-572 |
7.79e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.61 E-value: 7.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 330 RAPPMEMDAA-PAAGVVSLTEREMALAKDTASPTAKELALSSGTEVAPVKGMAPPPETEVAPGKDmAPPPETEGLGMAPP 408
Cdd:PRK10263 298 RATQPEYDEYdPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQP-VPGPQTGEPVIAPA 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 409 PETeVAPVKGMAPPPETEVAPVKGMAPPPEIEVASVKGMAP------PPETEVVPVKGMAPPPETEVVPVKGVAPPPETE 482
Cdd:PRK10263 377 PEG-YPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAqqpyyaPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQST 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 483 VTPGKDV--------PLLPEPEPSLAKDVVPPSETEVAPVpAKDMGTVRTPGKPSEGPQFASLRNEGPSA-----VPAAV 549
Cdd:PRK10263 456 FAPQSTYqteqtyqqPAAQEPLYQQPQPVEQQPVVEPEPV-VEETKPARPPLYYFEEVEEKRAREREQLAawyqpIPEPV 534
|
250 260
....*....|....*....|...
gi 987959268 550 ASPEPVTAvgqtSALPPDEASVP 572
Cdd:PRK10263 535 KEPEPIKS----SLKAPSVAAVP 553
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1680-1923 |
9.42e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.46 E-value: 9.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1680 SPKPAAVQERGRPEHATPSGTAKPEGPAAAsvtgnditaPPNKELPPSPEKKAKVVAGMPVAETKVPEKkaTPSKPASAP 1759
Cdd:PHA03247 256 APPPVVGEGADRAPETARGATGPPPPPEAA---------APNGAAAPPDGVWGAALAGAPLALPAPPDP--PPPAPAGDA 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1760 ASRPGS-RSTQAAPKAPAAASVASTGPSSRSAPTPLPRRPAGTKTEG----KPADAKKAVTKSAPADLSRAKSTSSSTAR 1834
Cdd:PHA03247 325 EEEDDEdGAMEVVSPLPRPRQHYPLGFPKRRRPTWTPPSSLEDLSAGrhhpKRASLPTRKRRSARHAATPFARGPGGDDQ 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 1835 KTAAGPGPGSP----AGAAPSRVKPTPVSPRASGTLAVDKKPTSArPSSLAPRLSRPATSASTPDLKNVRAKVGSTENIR 1910
Cdd:PHA03247 405 TRPAAPVPASVptpaPTPVPASAPPPPATPLPSAEPGSDDGPAPP-PERQPPAPATEPAPDDPDDATRKALDALRERRPP 483
|
250
....*....|...
gi 987959268 1911 HQPGGGRAKVEGR 1923
Cdd:PHA03247 484 EPPGADLAELLGR 496
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
513-600 |
9.75e-03 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 40.87 E-value: 9.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 987959268 513 PVPAKDMGTVRTPgKPSEGPQFASLRNEGPSAVPAAVAS--PEPVTAVGQTSALPPDEASVPEKLEQRQPlsrQPPEPPA 590
Cdd:PHA03269 42 PAPAPHQAASRAP-DPAVAPTSAASRKPDLAQAPTPAASekFDPAPAPHQAASRAPDPAVAPQLAAAPKP---DAAEAFT 117
|
90
....*....|
gi 987959268 591 APSGTLPTPA 600
Cdd:PHA03269 118 SAAQAHEAPA 127
|
|
| |
