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Conserved domains on  [gi|426220398|ref|XP_004004403|]
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GTP:AMP phosphotransferase AK3, mitochondrial isoform X1 [Ovis aries]

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11995178)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
12-190 3.72e-102

Adenylate kinase;


:

Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 293.45  E-value: 3.72e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNL-TQYNWLLD 90
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNdCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   91 GFPRTLPQAEALDR----AYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDRP 166
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 426220398  167 ETVVKRLKAYEAQTEPVLEYYRKK 190
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
12-190 3.72e-102

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 293.45  E-value: 3.72e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNL-TQYNWLLD 90
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNdCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   91 GFPRTLPQAEALDR----AYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDRP 166
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 426220398  167 ETVVKRLKAYEAQTEPVLEYYRKK 190
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 12-199 7.11e-94

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 273.54  E-value: 7.11e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNL-TQYNWLLD 90
Cdd:COG0563    5 LLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPdCANGFILD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  91 GFPRTLPQAEALDRA-----YQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDR 165
Cdd:COG0563   85 GFPRTVAQAEALDELlaelgIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRADDN 164

                        170       180       190
                 ....*....|....*....|....*....|....
gi 426220398 166 PETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGT 199
Cdd:COG0563  165 EETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 9-213 4.60e-92

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 269.10  E-value: 4.60e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398    9 RAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNL--TQYN 86
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNddNENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   87 WLLDGFPRTLPQAEALDR--AYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDD 164
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 426220398  165 RPETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGT-ETNKIWPHVYAFLQ 213
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
adk PRK00279
adenylate kinase; Reviewed
 12-213 8.01e-90

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 263.55  E-value: 8.01e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNL-TQYNWLLD 90
Cdd:PRK00279   5 LLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPdCKNGFLLD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  91 GFPRTLPQAEALDRAY-----QIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDR 165
Cdd:PRK00279  85 GFPRTIPQAEALDEMLkelgiKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQRADDN 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 426220398 166 PETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGTET-NKIWPHVYAFLQ 213
Cdd:PRK00279 165 EETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSiDEVFADILKALG 213
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 9-201 2.84e-85

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 251.00  E-value: 2.84e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   9 RAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQYN-W 87
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKgF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  88 LLDGFPRTLPQAEALDRAYQ----IDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIefnppktmGIDDLTGEPLVQRED 163
Cdd:cd01428   81 ILDGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 426220398 164 DRPETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGTET 201
Cdd:cd01428  153 DNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
12-190 3.72e-102

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 293.45  E-value: 3.72e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNL-TQYNWLLD 90
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNdCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   91 GFPRTLPQAEALDR----AYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDRP 166
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 426220398  167 ETVVKRLKAYEAQTEPVLEYYRKK 190
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 12-199 7.11e-94

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 273.54  E-value: 7.11e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNL-TQYNWLLD 90
Cdd:COG0563    5 LLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPdCANGFILD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  91 GFPRTLPQAEALDRA-----YQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDR 165
Cdd:COG0563   85 GFPRTVAQAEALDELlaelgIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRADDN 164

                        170       180       190
                 ....*....|....*....|....*....|....
gi 426220398 166 PETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGT 199
Cdd:COG0563  165 EETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 9-213 4.60e-92

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 269.10  E-value: 4.60e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398    9 RAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNL--TQYN 86
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNddNENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   87 WLLDGFPRTLPQAEALDR--AYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDD 164
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDAllEEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 426220398  165 RPETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGT-ETNKIWPHVYAFLQ 213
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
adk PRK00279
adenylate kinase; Reviewed
 12-213 8.01e-90

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 263.55  E-value: 8.01e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNL-TQYNWLLD 90
Cdd:PRK00279   5 LLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPdCKNGFLLD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  91 GFPRTLPQAEALDRAY-----QIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDR 165
Cdd:PRK00279  85 GFPRTIPQAEALDEMLkelgiKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQRADDN 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 426220398 166 PETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGTET-NKIWPHVYAFLQ 213
Cdd:PRK00279 165 EETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSiDEVFADILKALG 213
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 9-201 2.84e-85

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 251.00  E-value: 2.84e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   9 RAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQYN-W 87
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKgF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  88 LLDGFPRTLPQAEALDRAYQ----IDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIefnppktmGIDDLTGEPLVQRED 163
Cdd:cd01428   81 ILDGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 426220398 164 DRPETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGTET 201
Cdd:cd01428  153 DNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
PLN02674 PLN02674
adenylate kinase
 9-193 1.74e-62

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 195.10  E-value: 1.74e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   9 RAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLT-QYNW 87
Cdd:PLN02674  33 RLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKPScQKGF 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  88 LLDGFPRTLPQAEALD-----RAYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQRE 162
Cdd:PLN02674 113 ILDGFPRTVVQAQKLDemlakQGAKIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLIQRK 192

                        170       180       190
                 ....*....|....*....|....*....|.
gi 426220398 163 DDRPETVVKRLKAYEAQTEPVLEYYRKKGVL 193
Cdd:PLN02674 193 DDTAAVLKSRLEAFHKQTEPVIDYYAKKGVV 223
PRK14530 PRK14530
adenylate kinase; Provisional
 9-210 1.26e-51

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 166.50  E-value: 1.26e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   9 RAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLR-----GTEIGVlAKTFIDQGKLIPDDVMTRLVLHELKNLT 83
Cdd:PRK14530   5 RILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRANKQMdisdmDTEYDT-PGEYMDAGELVPDAVVNEIVEEALSDAD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  84 QYnwLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQRED 163
Cdd:PRK14530  84 GF--VLDGYPRNLEQAEYLESITDLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDECGGELIQRDD 161

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 426220398 164 DRPETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGTET-NKIWPHVYA 210
Cdd:PRK14530 162 DTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTpDEVWADIQD 209
PRK14526 PRK14526
adenylate kinase; Provisional
 13-189 7.28e-42

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 141.14  E-value: 7.28e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  13 MGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQY-NWLLDG 91
Cdd:PRK14526   6 LGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKNNdNFILDG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  92 FPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQREDDRPETVVK 171
Cdd:PRK14526  86 FPRNINQAKALDKFLPNIKIINFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQRKDDKEESLKT 165

                        170
                 ....*....|....*...
gi 426220398 172 RLKAYEAQTEPVLEYYRK 189
Cdd:PRK14526 166 RLQEYKLQTKPLIEFYSK 183
PLN02459 PLN02459
probable adenylate kinase
 13-196 1.65e-40

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 139.21  E-value: 1.65e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  13 MGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQ---YNWLL 89
Cdd:PLN02459  35 LGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEAGEEegeSGFIL 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  90 DGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNI------EFNPPKTMGIDDLTGEP-----L 158
Cdd:PLN02459 115 DGFPRTVRQAEILEGVTDIDLVVNLKLREEVLVEKCLGRRICSECGKNFNVadidlkGEDGRPGIVMPPLLPPPecaskL 194

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 426220398 159 VQREDDRPETVVKRLKAYEAQTEPVLEYYRKKGVLETF 196
Cdd:PLN02459 195 ITRADDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEF 232
PLN02842 PLN02842
nucleotide kinase
 12-187 1.98e-40

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 144.62  E-value: 1.98e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHEL--KNLTQYNWLL 89
Cdd:PLN02842   2 ISGAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLsrEDAKEKGWLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  90 DGFPRTLPQAEALDR-AYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNIEFNPPKTMGIDdltgEPLVQREDDRPET 168
Cdd:PLN02842  82 DGYPRSFAQAQSLEKlKIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKNFPPESEEIK----ARLITRPDDTEEK 157

                        170
                 ....*....|....*....
gi 426220398 169 VVKRLKAYEAQTEPVLEYY 187
Cdd:PLN02842 158 VKARLQIYKKNAEAILSTY 176
adk PRK02496
adenylate kinase; Provisional
 9-201 1.60e-39

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 134.49  E-value: 1.60e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   9 RAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNL-TQYNW 87
Cdd:PRK02496   3 RLIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPdAANGW 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  88 LLDGFPRTLPQAEALDR-----AYQIDTVINLNVPFEVIKQRLTARwihpgsgrvyniefnppktmgiddltgeplvQRE 162
Cdd:PRK02496  83 ILDGFPRKVTQAAFLDEllqeiGQSGERVVNLDVPDDVVVERLLAR-------------------------------GRK 131

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 426220398 163 DDRPETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGTET 201
Cdd:PRK02496 132 DDTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQS 170
PRK14527 PRK14527
adenylate kinase; Provisional
 13-201 3.05e-39

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 133.76  E-value: 3.05e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  13 MGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQYNWLLDGF 92
Cdd:PRK14527  12 LGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGMEPVRVIFDGF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  93 PRTLPQAEALDR-----AYQIDTVINLNVPFEVIKQRLTARWIHPGsgrvyniefnppktmgiddltgeplvqREDDRPE 167
Cdd:PRK14527  92 PRTLAQAEALDRlleelGARLLAVVLLEVPDEELIRRIVERARQEG---------------------------RSDDNEE 144

                        170       180       190
                 ....*....|....*....|....*....|....
gi 426220398 168 TVVKRLKAYEAQTEPVLEYYRKKGVLETFSGTET 201
Cdd:PRK14527 145 TVRRRQQVYREQTQPLVDYYEARGHLKRVDGLGT 178
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 6-192 9.82e-37

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 128.76  E-value: 9.82e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   6 RLLRAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQ- 84
Cdd:PTZ00088   5 GPLKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIAKVTDd 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  85 --YNWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPGSGRVYNI------EFNPPKTM---GIDDL 153
Cdd:PTZ00088  85 cfKGFILDGFPRNLKQCKELGKITNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNIahirsdPYDMPPILppaDCEGC 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 426220398 154 TGEP-LVQREDDRPETVVKRLKAYEAQTEPVLEYYRKKGV 192
Cdd:PTZ00088 165 KGNPkLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNENC 204
PRK14531 PRK14531
adenylate kinase; Provisional
 4-195 1.72e-36

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 126.46  E-value: 1.72e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   4 SARLLraaIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLT 83
Cdd:PRK14531   2 KQRLL---FLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQLKALN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  84 QYNWLLDGFPRTLPQAEALDRAYQ-----IDTVINLNVPFEVIKQRLTARwihpgsgrvyniefnppktmgiddltgepl 158
Cdd:PRK14531  79 SGGWLLDGFPRTVAQAEALEPLLEelkqpIEAVVLLELDDAVLIERLLAR------------------------------ 128

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 426220398 159 vQREDDRPETVVKRLKAYEAQTEPVLEYYRKKGVLET 195
Cdd:PRK14531 129 -GRADDNEAVIRNRLEVYREKTAPLIDHYRQRGLLQS 164
PRK14532 PRK14532
adenylate kinase; Provisional
 12-198 4.17e-34

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 120.70  E-value: 4.17e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHEL-KNLTQYNWLLD 90
Cdd:PRK14532   5 LFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLpEAEAAGGAIFD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  91 GFPRTLPQAEALD-----RAYQIDTVINLNVPFEVIKQRLTARWIHPGsgrvyniefnppktmgiddltgeplvqREDDR 165
Cdd:PRK14532  85 GFPRTVAQAEALDkmlasRGQKIDVVIRLKVDDEALIERIVKRFEEQG---------------------------RPDDN 137

                        170       180       190
                 ....*....|....*....|....*....|...
gi 426220398 166 PETVVKRLKAYEAQTEPVLEYYRKKGVLETFSG 198
Cdd:PRK14532 138 PEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDG 170
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 12-199 2.15e-33

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 118.63  E-value: 2.15e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLR-GTEIGVLAKTFIDQGKLIPDDVMTRLVLHELK-NLTQYNWLL 89
Cdd:TIGR01359   4 VLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKReGSENGSLIESYIKEGKIVPSEVTVELLKKAIQeDGSSKKFLI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   90 DGFPRTLPQAEA----LDRAYQIDTVINLNVPFEVIKQRLTARWIHPGsgrvyniefnppktmgiddltgeplvqREDDR 165
Cdd:TIGR01359  84 DGFPRNEENLEAweklMDNKVNFKFVLFFDCPEETMIKRLLKRGQTSG---------------------------RVDDN 136

                         170       180       190
                  ....*....|....*....|....*....|....
gi 426220398  166 PETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGT 199
Cdd:TIGR01359 137 IETLKKRFRTYNEETLPIIEHFENKGKVKEINAE 170
PRK13808 PRK13808
adenylate kinase; Provisional
 8-198 2.14e-32

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 119.99  E-value: 2.14e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   8 LRAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQYN- 86
Cdd:PRK13808   1 MRLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPDAANg 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  87 WLLDGFPRTLPQAEALDR-----AYQIDTVINLNVPFEVIKQRLTARwIHPGSGRvyniefnppktmgiddltGEPLvqR 161
Cdd:PRK13808  81 FILDGFPRTVPQAEALDAllkdkQLKLDAVVELRVNEGALLARVETR-VAEMRAR------------------GEEV--R 139

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 426220398 162 EDDRPETVVKRLKAYEAQTEPVLEYYRKKGVLETFSG 198
Cdd:PRK13808 140 ADDTPEVLAKRLASYRAQTEPLVHYYSEKRKLLTVDG 176
PRK14528 PRK14528
adenylate kinase; Provisional
 9-201 4.07e-32

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 115.49  E-value: 4.07e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   9 RAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQYN-W 87
Cdd:PRK14528   3 NIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKNgF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  88 LLDGFPRTLPQAEALDR-----AYQIDTVINLNVPFEVIKQRLTARWIHPGsgrvyniefnppktmgiddltgeplvqRE 162
Cdd:PRK14528  83 LLDGFPRTVEQADALDAllkneGKSIDKAINLEVPDGELLKRLLGRAEIEG---------------------------RA 135

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 426220398 163 DDRPETVVKRLKAYEAQTEPVLEYYRKKGVLETFSGTET 201
Cdd:PRK14528 136 DDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGS 174
PRK14529 PRK14529
adenylate kinase; Provisional
 12-176 1.08e-31

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 115.20  E-value: 1.08e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQYNWLLDG 91
Cdd:PRK14529   5 IFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETLKQDGKNGWLLDG 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  92 FPRTLPQAEALDRAYQ-----IDTVINLNVPFEVIKQRLTARWI------HPGsgrvyNIEFNPPKTMG-IDDLTGEPLV 159
Cdd:PRK14529  85 FPRNKVQAEKLWEALQkegmkLDYVIEILLPREVAKNRIMGRRLckndnnHPN-----NIFIDAIKPDGdVCRVCGGELS 159

                        170
                 ....*....|....*...
gi 426220398 160 QREDDRPETVV-KRLKAY 176
Cdd:PRK14529 160 TRADDQDEEAInKRHDIY 177
PLN02200 PLN02200
adenylate kinase family protein
 12-208 2.70e-27

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 104.20  E-value: 2.70e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHELKNLTQYNWLLDG 91
Cdd:PLN02200  48 VLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSDNNKFLIDG 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  92 FPRTLPQAEALDR--AYQIDTVINLNVPFEVIKQRLTARwihpGSGRVyniefnppktmgiddltgeplvqreDDRPETV 169
Cdd:PLN02200 128 FPRTEENRIAFERiiGAEPNVVLFFDCPEEEMVKRVLNR----NQGRV-------------------------DDNIDTI 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 426220398 170 VKRLKAYEAQTEPVLEYYRKKGVLETFSGTET-NKIWPHV 208
Cdd:PLN02200 179 KKRLKVFNALNLPVIDYYSKKGKLYTINAVGTvDEIFEQV 218
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 12-195 7.91e-27

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 101.82  E-value: 7.91e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   12 IMGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTEIGVLAKTFIDQGKLIPDDVMTRLVLHEL--KNLTQYNWLL 89
Cdd:TIGR01360   8 IVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMvaALGTSKGFLI 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   90 DGFPRTLPQAEALDRAYQIDTvinLNVPFEVIKQRLTARWIHPG--SGRVyniefnppktmgiddltgeplvqreDDRPE 167
Cdd:TIGR01360  88 DGYPREVKQGEEFERRIGPPT---LVLYFDCSEDTMVKRLLKRAetSGRV-------------------------DDNEK 139

                         170       180
                  ....*....|....*....|....*...
gi 426220398  168 TVVKRLKAYEAQTEPVLEYYRKKGVLET 195
Cdd:TIGR01360 140 TIKKRLETYYKATEPVIAYYETKGKLRK 167
AAA_17 pfam13207
AAA domain;
13-141 1.13e-24

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 94.61  E-value: 1.13e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   13 MGAPGSGKGTVSSRITKHFELKHLSSGDLLRDNMLRGTeiGVLAKTFIDQGKLIPDDVMTRLVLHEL-KNLTQYNWLLDG 91
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAERIaEEAGEGGVIVDG 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 426220398   92 FPRTLPQAEALD-------RAYQIDTVINLNVPFEVIKQRLTARwihPGSGRVY-NIE 141
Cdd:pfam13207  79 HPRIKTPAGYLPglpvevlRELKPDAIILLEADPEEILERRLKD---RTRGRDDdSEE 133
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 128-163 6.09e-17

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 71.34  E-value: 6.09e-17
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 426220398  128 RWIHPGSGRVYNIEFNPPKTMGIDDLTGEPLVQRED 163
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
AAA_18 pfam13238
AAA domain;
11-128 5.25e-08

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 50.12  E-value: 5.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398   11 AIMGAPGSGKGTVSSRITKHFELkHLSSGDLLRDNMLRGTEIGvlaktFIDQGKLIPDDVMTRLV--LHELKNLTQY-NW 87
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSKRLGF-GDNVRDLALENGLVLGDDP-----ETRESKRLDEDKLDRLLdlLEENAALEEGgNL 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 426220398   88 LLDGFPrtlpqAEALDRAYQIDTVINLNVPFEVIKQRLTAR 128
Cdd:pfam13238  76 IIDGHL-----AELEPERAKDLVGIVLRASPEELLERLEKR 111
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 11-56 4.57e-06

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 44.78  E-value: 4.57e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 426220398  11 AIMGAPGSGKGTVSSRITKHFELKHLSSGDllrdnmLRGTEIGVLA 56
Cdd:cd02020    3 AIDGPAGSGKSTVAKLLAKKLGLPYLDTGG------IRTEEVGKLA 42
PRK04182 PRK04182
cytidylate kinase; Provisional
 8-44 4.66e-06

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 45.57  E-value: 4.66e-06
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 426220398   8 LRAAIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRD 44
Cdd:PRK04182   1 MIITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRE 37
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
11-128 1.21e-05

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 44.13  E-value: 1.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  11 AIMGAPGSGKGTVSSRITKHFELKHLSSgDLLRdNMLRGTEIGVLAKTfidqgklipdDVMTRLVLHELKNLTQYNwLLD 90
Cdd:COG0645    3 LVCGLPGSGKSTLARALAERLGAVRLRS-DVVR-KRLFGAGLAPLERS----------PEATARTYARLLALAREL-LAA 69

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 426220398  91 GFP----------RTLPQAEALDRAYQID-TVINLNVPFEVIKQRLTAR 128
Cdd:COG0645   70 GRSvildatflrrAQREAFRALAEEAGAPfVLIWLDAPEEVLRERLEAR 118
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 12-131 1.31e-05

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 43.78  E-value: 1.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  12 IMGAPGSGKGTVSSRITKHFELKHLSSGDL----LRDNMLRGteigvlaktfidqgklIP---DDVMTRlvlheLKNLTQ 84
Cdd:cd02021    4 VMGVSGSGKSTVGKALAERLGAPFIDGDDLhppaNIAKMAAG----------------IPlndEDRWPW-----LQALTD 62

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 426220398  85 --YNWLLDGFPRTLPQAEALDRAYQI----------DTVINLNVPFEVIKQRLTARWIH 131
Cdd:cd02021   63 alLAKLASAGEGVVVACSALKRIYRDilrggaanprVRFVHLDGPREVLAERLAARKGH 121
PRK09270 PRK09270
nucleoside triphosphate hydrolase domain-containing protein; Reviewed
 11-136 9.25e-04

nucleoside triphosphate hydrolase domain-containing protein; Reviewed


Pssm-ID: 236442  Cd Length: 229  Bit Score: 39.15  E-value: 9.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  11 AIMGAPGSGKGTVSSRItkHFELK---------------HLSSGDL-------------------LRDNM--LRGTEIGV 54
Cdd:PRK09270  37 GIAGPPGAGKSTLAEFL--EALLQqdgelpaiqvpmdgfHLDNAVLdahglrprkgapetfdvagLAALLrrLRAGDDEV 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 426220398  55 LAKTF-------IDQGKLIPDDvmTRLVLhelknlTQYNWLLdgfprtLPQaEALDRAYQI-DTVINLNVPFEVIKQRLT 126
Cdd:PRK09270 115 YWPVFdrsledpVADAIVVPPT--ARLVI------VEGNYLL------LDE-EPWRRLAGLfDFTIFLDAPAEVLRERLV 179

                        170
                 ....*....|
gi 426220398 127 ARWIHPGSGR 136
Cdd:PRK09270 180 ARKLAGGLSP 189
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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