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Conserved domains on  [gi|110556654|ref|NP_034978|]
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transcriptional activator Myb isoform 2 [Mus musculus]

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List of domain hits

Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind ...
94-138 1.95e-16

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


:

Pssm-ID: 238096  Cd Length: 45  Bit Score: 74.15  E-value: 1.95e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 110556654  94 PWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHL 138
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind ...
42-86 3.46e-16

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


:

Pssm-ID: 238096  Cd Length: 45  Bit Score: 73.76  E-value: 3.46e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 110556654  42 RWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVL 86
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind ...
146-186 2.28e-13

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


:

Pssm-ID: 238096  Cd Length: 45  Bit Score: 65.67  E-value: 2.28e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 110556654 146 SWTEEEDRIIYQAHKRLG-NRWAEIAKLLPGRTDNAIKNHWN 186
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWR 42
Cmyb_C pfam09316
C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb ...
402-563 5.34e-75

C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb and the viral transforming protein myb. Truncation of the domain results in 'activation' of c-myb and subsequent tumorigenesis.


:

Pssm-ID: 255282  Cd Length: 168  Bit Score: 239.74  E-value: 5.34e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  402 FLNTSSNHESSGLDAPTLPSTPLIGHKLTPC----RDQTVKTQKENSIFRTPAIKRSILESSPRTPTPFKHALAAQEIKY 477
Cdd:pfam09316   6 FLNSSTKQDHLDLENPSLTSTPVCSQKAIVTtplhRDKTPLLQKENSGFRTPNIRRSILDSTPRTPTPFKNALAAQEKKY 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  478 GPLKMLPQTPSHAVEDLQDVIKQESDESGIVAEFQEsgpPLLKKIKQEVESPTEKSGNFFCSNHWAENSLSTQLFSQASP 557
Cdd:pfam09316  86 GPLKPLPQTPSHLEEDIKEVIKQETGEDLIIVEEVE---PPLKKIKQEVESPMKKVRKSLALDIWEGEDLNAQLLTPDSP 162

                  ....*.
gi 110556654  558 VADAPN 563
Cdd:pfam09316 163 AREQPN 168
LMSTEN pfam07988
LMSTEN motif; This region of Myb proteins has previously been described as the transcriptional ...
266-313 2.82e-22

LMSTEN motif; This region of Myb proteins has previously been described as the transcriptional activation domain present in the vertebrate c-Myb and A-Myb, but neither vertebrate B-Myb proteins nor Myb proteins of invertebrates. Because vertebrate B-Myb (but neither A-Myb nor c-Myb) can partially complement Drosophila Myb null mutants, this region appears to have been a relatively recent insertion.


:

Pssm-ID: 149202  Cd Length: 48  Bit Score: 91.04  E-value: 2.82e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 110556654  266 HVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQ 313
Cdd:pfam07988   1 EDNCIEHPQASTAFIQQHFVDEDPDKEKRIKELELLLMSTENEVRRKR 48
 
Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind ...
94-138 1.95e-16

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096  Cd Length: 45  Bit Score: 74.15  E-value: 1.95e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 110556654  94 PWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHL 138
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind ...
42-86 3.46e-16

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096  Cd Length: 45  Bit Score: 73.76  E-value: 3.46e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 110556654  42 RWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVL 86
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind ...
146-186 2.28e-13

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096  Cd Length: 45  Bit Score: 65.67  E-value: 2.28e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 110556654 146 SWTEEEDRIIYQAHKRLG-NRWAEIAKLLPGRTDNAIKNHWN 186
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWR 42
Cmyb_C pfam09316
C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb ...
402-563 5.34e-75

C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb and the viral transforming protein myb. Truncation of the domain results in 'activation' of c-myb and subsequent tumorigenesis.


Pssm-ID: 255282  Cd Length: 168  Bit Score: 239.74  E-value: 5.34e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  402 FLNTSSNHESSGLDAPTLPSTPLIGHKLTPC----RDQTVKTQKENSIFRTPAIKRSILESSPRTPTPFKHALAAQEIKY 477
Cdd:pfam09316   6 FLNSSTKQDHLDLENPSLTSTPVCSQKAIVTtplhRDKTPLLQKENSGFRTPNIRRSILDSTPRTPTPFKNALAAQEKKY 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  478 GPLKMLPQTPSHAVEDLQDVIKQESDESGIVAEFQEsgpPLLKKIKQEVESPTEKSGNFFCSNHWAENSLSTQLFSQASP 557
Cdd:pfam09316  86 GPLKPLPQTPSHLEEDIKEVIKQETGEDLIIVEEVE---PPLKKIKQEVESPMKKVRKSLALDIWEGEDLNAQLLTPDSP 162

                  ....*.
gi 110556654  558 VADAPN 563
Cdd:pfam09316 163 AREQPN 168
LMSTEN pfam07988
LMSTEN motif; This region of Myb proteins has previously been described as the transcriptional ...
266-313 2.82e-22

LMSTEN motif; This region of Myb proteins has previously been described as the transcriptional activation domain present in the vertebrate c-Myb and A-Myb, but neither vertebrate B-Myb proteins nor Myb proteins of invertebrates. Because vertebrate B-Myb (but neither A-Myb nor c-Myb) can partially complement Drosophila Myb null mutants, this region appears to have been a relatively recent insertion.


Pssm-ID: 149202  Cd Length: 48  Bit Score: 91.04  E-value: 2.82e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 110556654  266 HVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQ 313
Cdd:pfam07988   1 EDNCIEHPQASTAFIQQHFVDEDPDKEKRIKELELLLMSTENEVRRKR 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
92-138 3.84e-18

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 249715  Cd Length: 47  Bit Score: 79.10  E-value: 3.84e-18
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 110556654   92 KGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHL 138
Cdd:pfam00249   1 RGPWTPEEDELLIEAVKKHGNGNWKKIAKHLPGRTDNQCKNRWNNYL 47
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
43-103 4.09e-17

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 258184  Cd Length: 59  Bit Score: 76.59  E-value: 4.09e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 110556654   43 WTREEDEKLKKLVEQNGtDDWKVIANYLpNRTDVQCQHRWQKVLNPELIKGPWTKEEDQRV 103
Cdd:pfam13921   1 WTEEEDEILLKLVEKYG-NDWKQIAEEL-GRTPSACRDRWRRKLRPKRKRGPWTKEEDQRL 59
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
92-140 9.04e-17

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842  Cd Length: 49  Bit Score: 75.34  E-value: 9.04e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 110556654    92 KGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNP 140
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
40-88 1.08e-16

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842  Cd Length: 49  Bit Score: 74.95  E-value: 1.08e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 110556654    40 KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNP 88
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLKP 49
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
144-189 1.15e-14

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 249715  Cd Length: 47  Bit Score: 69.47  E-value: 1.15e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 110556654  144 KTSWTEEEDRIIYQAHKRLGNR-WAEIAKLLPGRTDNAIKNHWNSTM 189
Cdd:pfam00249   1 RGPWTPEEDELLIEAVKKHGNGnWKKIAKHLPGRTDNQCKNRWNNYL 47
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
144-191 1.45e-13

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842  Cd Length: 49  Bit Score: 66.09  E-value: 1.45e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 110556654   144 KTSWTEEEDRIIYQAHKRLG-NRWAEIAKLLPGRTDNAIKNHWNSTMRR 191
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
89-191 3.31e-29

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 120.66  E-value: 3.31e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  89 ELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAE 168
Cdd:COG5147   17 KRKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWST 96
                         90       100
                 ....*....|....*....|...
gi 110556654 169 IAKLLPGRTDNAIKNHWNSTMRR 191
Cdd:COG5147   97 IADYKDRRTAQQCVERYVNTLED 119
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
92-197 6.99e-28

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 112.48  E-value: 6.99e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  92 KGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKG-RIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIA 170
Cdd:PLN03212  25 RGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLlRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWSLIA 104
                         90       100
                 ....*....|....*....|....*..
gi 110556654 171 KLLPGRTDNAIKNHWNSTMRRKVEQEG 197
Cdd:PLN03212 105 GRIPGRTDNEIKNYWNTHLRKKLLRQG 131
 
Name Accession Description Interval E-value
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind ...
94-138 1.95e-16

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096  Cd Length: 45  Bit Score: 74.15  E-value: 1.95e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 110556654  94 PWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHL 138
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind ...
42-86 3.46e-16

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096  Cd Length: 45  Bit Score: 73.76  E-value: 3.46e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 110556654  42 RWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVL 86
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind ...
146-186 2.28e-13

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096  Cd Length: 45  Bit Score: 65.67  E-value: 2.28e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 110556654 146 SWTEEEDRIIYQAHKRLG-NRWAEIAKLLPGRTDNAIKNHWN 186
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWR 42
Cmyb_C pfam09316
C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb ...
402-563 5.34e-75

C-myb, C-terminal; Members of this family are predominantly found in the proto-oncogene c-myb and the viral transforming protein myb. Truncation of the domain results in 'activation' of c-myb and subsequent tumorigenesis.


Pssm-ID: 255282  Cd Length: 168  Bit Score: 239.74  E-value: 5.34e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  402 FLNTSSNHESSGLDAPTLPSTPLIGHKLTPC----RDQTVKTQKENSIFRTPAIKRSILESSPRTPTPFKHALAAQEIKY 477
Cdd:pfam09316   6 FLNSSTKQDHLDLENPSLTSTPVCSQKAIVTtplhRDKTPLLQKENSGFRTPNIRRSILDSTPRTPTPFKNALAAQEKKY 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  478 GPLKMLPQTPSHAVEDLQDVIKQESDESGIVAEFQEsgpPLLKKIKQEVESPTEKSGNFFCSNHWAENSLSTQLFSQASP 557
Cdd:pfam09316  86 GPLKPLPQTPSHLEEDIKEVIKQETGEDLIIVEEVE---PPLKKIKQEVESPMKKVRKSLALDIWEGEDLNAQLLTPDSP 162

                  ....*.
gi 110556654  558 VADAPN 563
Cdd:pfam09316 163 AREQPN 168
LMSTEN pfam07988
LMSTEN motif; This region of Myb proteins has previously been described as the transcriptional ...
266-313 2.82e-22

LMSTEN motif; This region of Myb proteins has previously been described as the transcriptional activation domain present in the vertebrate c-Myb and A-Myb, but neither vertebrate B-Myb proteins nor Myb proteins of invertebrates. Because vertebrate B-Myb (but neither A-Myb nor c-Myb) can partially complement Drosophila Myb null mutants, this region appears to have been a relatively recent insertion.


Pssm-ID: 149202  Cd Length: 48  Bit Score: 91.04  E-value: 2.82e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 110556654  266 HVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQ 313
Cdd:pfam07988   1 EDNCIEHPQASTAFIQQHFVDEDPDKEKRIKELELLLMSTENEVRRKR 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
92-138 3.84e-18

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 249715  Cd Length: 47  Bit Score: 79.10  E-value: 3.84e-18
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 110556654   92 KGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHL 138
Cdd:pfam00249   1 RGPWTPEEDELLIEAVKKHGNGNWKKIAKHLPGRTDNQCKNRWNNYL 47
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
43-103 4.09e-17

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 258184  Cd Length: 59  Bit Score: 76.59  E-value: 4.09e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 110556654   43 WTREEDEKLKKLVEQNGtDDWKVIANYLpNRTDVQCQHRWQKVLNPELIKGPWTKEEDQRV 103
Cdd:pfam13921   1 WTEEEDEILLKLVEKYG-NDWKQIAEEL-GRTPSACRDRWRRKLRPKRKRGPWTKEEDQRL 59
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
40-86 6.71e-17

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 249715  Cd Length: 47  Bit Score: 75.64  E-value: 6.71e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 110556654   40 KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVL 86
Cdd:pfam00249   1 RGPWTPEEDELLIEAVKKHGNGNWKKIAKHLPGRTDNQCKNRWNNYL 47
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
92-140 9.04e-17

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842  Cd Length: 49  Bit Score: 75.34  E-value: 9.04e-17
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 110556654    92 KGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNP 140
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
40-88 1.08e-16

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842  Cd Length: 49  Bit Score: 74.95  E-value: 1.08e-16
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 110556654    40 KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNP 88
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLKP 49
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
95-155 1.44e-16

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 258184  Cd Length: 59  Bit Score: 75.05  E-value: 1.44e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 110556654   95 WTKEEDQRVIELVQKYGPKrWSVIAKHLkGRIGKQCRERWHNHLNPEVKKTSWTEEEDRII 155
Cdd:pfam13921   1 WTEEEDEILLKLVEKYGND-WKQIAEEL-GRTPSACRDRWRRKLRPKRKRGPWTKEEDQRL 59
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
144-189 1.15e-14

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 249715  Cd Length: 47  Bit Score: 69.47  E-value: 1.15e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 110556654  144 KTSWTEEEDRIIYQAHKRLGNR-WAEIAKLLPGRTDNAIKNHWNSTM 189
Cdd:pfam00249   1 RGPWTPEEDELLIEAVKKHGNGnWKKIAKHLPGRTDNQCKNRWNNYL 47
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
144-191 1.45e-13

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842  Cd Length: 49  Bit Score: 66.09  E-value: 1.45e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 110556654   144 KTSWTEEEDRIIYQAHKRLG-NRWAEIAKLLPGRTDNAIKNHWNSTMRR 191
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
147-201 6.16e-09

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 258184  Cd Length: 59  Bit Score: 53.10  E-value: 6.16e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 110556654  147 WTEEEDRIIYQAHKRLGNRWAEIAKLLpGRTDNAIKNHWNSTMRRKVEQEGYLQE 201
Cdd:pfam13921   1 WTEEEDEILLKLVEKYGNDWKQIAEEL-GRTPSACRDRWRRKLRPKRKRGPWTKE 54
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
94-136 6.39e-07

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558  Cd Length: 50  Bit Score: 47.18  E-value: 6.39e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 110556654  94 PWTKEEDQRVIELVQKYGPKRWSVIAKH---LKGRIGKQCRERWHN 136
Cdd:cd11660    2 KWTDEEDEALVEGVEKYGVGNWAKILKDyffVNNRTSVDLKDKWRN 47
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
88-134 9.69e-07

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557  Cd Length: 53  Bit Score: 46.53  E-value: 9.69e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 110556654  88 PELIKGPWTKEEDQRVIELVQKYgPKRWSVIAKhLKGRIGKQCRERW 134
Cdd:cd11659    1 PSIKKTEWTREEDEKLLHLAKLL-PTQWRTIAP-IVGRTAQQCLERY 45
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
38-87 3.38e-06

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557  Cd Length: 53  Bit Score: 44.99  E-value: 3.38e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 110556654  38 LGKTRWTREEDEKLKKLVEQNGTdDWKVIANYLpNRTDVQCQHRWQKVLN 87
Cdd:cd11659    3 IKKTEWTREEDEKLLHLAKLLPT-QWRTIAPIV-GRTAQQCLERYNKLLD 50
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
42-82 8.32e-06

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558  Cd Length: 50  Bit Score: 43.71  E-value: 8.32e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 110556654  42 RWTREEDEKLKKLVEQNGTDDWKVIANYLP---NRTDVQCQHRW 82
Cdd:cd11660    2 KWTDEEDEALVEGVEKYGVGNWAKILKDYFfvnNRTSVDLKDKW 45
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
140-179 3.20e-05

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557  Cd Length: 53  Bit Score: 42.30  E-value: 3.20e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 110556654 140 PEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLpGRTDN 179
Cdd:cd11659    1 PSIKKTEWTREEDEKLLHLAKLLPTQWRTIAPIV-GRTAQ 39
SGNH_arylesterase_like cd01839
SGNH_hydrolase subfamily, similar to arylesterase (7-aminocephalosporanic acid-deacetylating ...
28-74 3.06e-03

SGNH_hydrolase subfamily, similar to arylesterase (7-aminocephalosporanic acid-deacetylating enzyme) of A. tumefaciens. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.


Pssm-ID: 238877  Cd Length: 208  Bit Score: 38.02  E-value: 3.06e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 110556654  28 GLLPKSGKRHLGKTRWTreedEKLKKLVEQNGTdDWKVIANYLPNRT 74
Cdd:cd01839   12 GIIPDTGGRYPFEDRWP----GVLEKALGANGE-NVRVIEDGLPGRT 53
Myb_DNA-bind_4 pfam13837
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb ...
40-82 3.75e-03

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT-like DNA binding domains. In particular pfam10545 seems most related. This family is greatly expanded in plants and appears in several proteins annotated as transposon proteins.


Pssm-ID: 258112  Cd Length: 82  Bit Score: 36.09  E-value: 3.75e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 110556654   40 KTRWTREEDEKL---------KKLVEQNGTDDWKVIANYL----PNRTDVQCQHRW 82
Cdd:pfam13837   1 RNKWTEAETLALieiwgeldlRFQGTKRNKALWEEIAEKMaelgYNRSAKQCKEKW 56
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
89-191 3.31e-29

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 120.66  E-value: 3.31e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  89 ELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAE 168
Cdd:COG5147   17 KRKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWST 96
                         90       100
                 ....*....|....*....|...
gi 110556654 169 IAKLLPGRTDNAIKNHWNSTMRR 191
Cdd:COG5147   97 IADYKDRRTAQQCVERYVNTLED 119
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
92-197 6.99e-28

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 112.48  E-value: 6.99e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  92 KGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKG-RIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIA 170
Cdd:PLN03212  25 RGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLlRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWSLIA 104
                         90       100
                 ....*....|....*....|....*..
gi 110556654 171 KLLPGRTDNAIKNHWNSTMRRKVEQEG 197
Cdd:PLN03212 105 GRIPGRTDNEIKNYWNTHLRKKLLRQG 131
PLN03091 PLN03091
hypothetical protein; Provisional
89-197 1.02e-27

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 115.46  E-value: 1.02e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  89 ELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKhLKG--RIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRW 166
Cdd:PLN03091  11 KLRKGLWSPEEDEKLLRHITKYGHGCWSSVPK-QAGlqRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRW 89
                         90       100       110
                 ....*....|....*....|....*....|.
gi 110556654 167 AEIAKLLPGRTDNAIKNHWNSTMRRKVEQEG 197
Cdd:PLN03091  90 SQIAAQLPGRTDNEIKNLWNSCLKKKLRQRG 120
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
35-184 4.17e-06

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 48.25  E-value: 4.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  35 KRHLGKTRWTREEDEKLKKLVEQNGTdDWKVIANYLPNRTDVQCQHRWQKVLNPELiKGPWTKEEDQRVIELVQ--KYGP 112
Cdd:COG5147   67 NPQLKKKNWSEEEDEQLIDLDKELGT-QWSTIADYKDRRTAQQCVERYVNTLEDLS-STHDSKLQRRNEFDKIDpfNENS 144
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 110556654 113 KRWSVIAKhlkgrigKQCRERWHNHL------NPEVKKtSWTEEEDriiyqaHKRLGNRWAEIAKLLPGRTDNAIKNH 184
Cdd:COG5147  145 ARRPDIYE-------DELLEREVNREasyrlrVPRVSK-ADVKPRE------KGEENNPDIEDLQEMKELKSASITRH 208
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
40-177 7.13e-06

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 47.47  E-value: 7.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110556654  40 KTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGpKRWSVIA 119
Cdd:COG5147  239 KKGLSRKQFCERIWSTDRDEDKFWPNIYKKLPYRDKKSIYKHLRRKYNIFEQRGKWTKEEEQELAKLVVEHG-GSWTEIG 317
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 110556654 120 KhLKGRIGKQCRERWHNHLNP--EVKKTSWT-EEEDRII-------YQAHKRLGNRWAEIAKLLPGRT 177
Cdd:COG5147  318 K-LLGRMPNDCRDRWRDYVKCgdTLKRNRWSiEEEELLDkvvnemrLEAQQSSRILWLLIAQNIRNRL 384
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.11
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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