NCBI Conserved Domain Search

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Conserved domains on [gi\|94970869\|ref\|YP_592917.1\|]
diguanylate cyclase [Candidatus Koribacter versatilis Ellin345]

Graphical summary show options »	Show site features Horizontal zoom: ×	?



List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

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of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

133472

cd01949

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as domain of unknown function 1 (DUF1). It is widely present in bacteria and often links to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain has been suggested to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesiveness in bacteria.

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

true

false

true

157

7e-47

183.56

99.36

4,303,1,67,371,68,49,422,117,13,436,130,27

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 304 DWLTDLPNRRHFDMRFNSEWRRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCLAKLGSVMAASVkRSADFVARYGGE 383
cd01949       2 DPLTGLPNRRAFEERLERLLARARRSGRPLALLLIDLDHFKQINDTYGHAAGDEVLKEVARRLRSSL-RESDLVARLGGD 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 384 EFVVILPETTATGAGIVAANVMEAVAALELPHAGSPHkqVSVSVGIAYAHPDiGAEPSELVRSADRALYTAKRDGRNCVR 463
cd01949      81 EFAILLPGTDLEEAEELAERLRKAIEEPFFIDGEEIR--VTASIGIAEYPED-GEDLEELLRRADKALYQAKRSGRNRVV 157

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

110022

pfam00990

GGDEF

GGDEF domain

false

160

1e-45

179.36

100.00

4,300,0,73,374,73,46,420,120,15,436,135,25

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 301 VYVDWLTDLPNRRHFDMRFNSEWRRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCLAKLGSVMAASVKRSaDFVARY 380
pfam00990     1 AAHDPLTGLPNRRYFEEELEQELQRAQRRQSPLALLLLDLDNFKRINDTYGHAVGDEVLQEVAQRLSSSLRRS-DLVARL 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 381 GGEEFVVILPETTATGAGIVAANVMEAVAALELPHAGSPH-KQVSVSVGIAYAHPDiGAEPSELVRSADRALYTAKRDGR 459
pfam00990    80 GGDEFAILLPDTSLEGAQELAERIRRLLAALKIPHTLSGLpLYVTISIGIAAYPND-GEDAEDLLKRADQALYQAKNQGR 158


                ..
gi 94970869 460 NC 461
pfam00990   159 NR 160

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

129356

TIGR00254

GGDEF

diguanylate cyclase (GGDEF) domain

false

165

9e-45

176.37

98.18

3,301,2,69,371,71,64,436,135,29

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 302 YVDWLTDLPNRRHFDMRFNSEWRRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCLAKLGSVMAASVkRSADFVARYG 381
TIGR00254     3 VRDPLTGLYNRRYLEEMLDSELKRARRFQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSV-RGSDVVGRYG 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 382 GEEFVVILPETTATGAGIVAANVMEAVAALELPHAGSPHKQVSVSVGIAYAHPDiGAEPSELVRSADRALYTAKRDGRNC 461
TIGR00254    82 GEEFVVILPGTPLEDALSKAERLRDAINSKPIEVAGSETLTVTVSIGVACYPGH-GLTLEELLKRADEALYQAKKAGRNR 160


                ....
gi 94970869 462 VRVA 465
TIGR00254   161 VVVA 164

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

128563

smart00267

GGDEF

diguanylate cyclase

false

163

9e-43

169.74

99.39

4,299,1,74,374,75,46,422,121,13,436,134,29

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 300 LVYVDWLTDLPNRRHFDMRFNSEWRRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCLAKLGSVMAASVKRSaDFVAR 379
smart00267    2 LAFRDPLTGLPNRRYFEEELEQELQRAQRQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRPG-DLLAR 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 380 YGGEEFVVILPETTATGAGIVAANVMEAVAALELPHAGSPHkqVSVSVGIAYAHPDiGAEPSELVRSADRALYTAKRDGR 459
smart00267   81 LGGDEFALLLPETSLEEAIALAERILQQLREPIIIHGIPLY--LTISIGVAAYPNP-GEDAEDLLKRADTALYQAKKAGR 157


                ....*.
gi 94970869 460 NCVRVA 465
smart00267  158 NQVAVY 163

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

32381

COG2199

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction...

false

181

8e-40

159.90

99.45

3,282,1,88,371,89,38,411,127,54

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 283 LAAVLGERDRLHERLTGLVYVDWLTDLPNRRHFDMRFNSEWRRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCLAKL 362
COG2199       2 LLRLLTRLRKAEERLERLALHDPLTGLPNRRAFEERLERALARARRHGEPLALLLLDLDHFKQINDTYGHAAGDEVLREV 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 363 GSVMAASVkRSADFVARYGGEEFVVILPETTATGAGIVAANVMEAVAalELPHAGSPHKQVSVSVGIAYAHPDIGAEPSE 442
COG2199      82 ARRLRSNL-REGDLVARLGGDEFAVLLPGTSLEEAARLAERIRAALE--EPFFLGGEELRVTVSIGVALYPEDGSDDAEL 158

                       170       180
                ....*....|....*....|...
gi 94970869 443 LVRSADRALYTAKRDGRNCVRVA 465
COG2199     159 LLRRADLALYRAKRAGRNRVVVF 181

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

113982

pfam05231

MASE1

true

false

298

2e-10

62.08

50.00

2,26,18,120,146,141,26

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869  27 LTLTRGEDRVAAIWLSNGVLVVLLLSKGKTPTLPLVMIGFLANLLANRVAGDQWLQASSLAAINALEVVIAYALLTRRGR 106
pfam05231    19 LALALVSSGIAAIWLPTGLRLAALLLFGRRYWPGILLGDVLASLFLGLLSGLGLLLALLILLVNALEALLAVALLRRLLP 98

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 94970869 107 EVDLRDPSGLGRFVLWGAIVAPLICSLLGTTVVVASRGGD---FQATLRVWFLADALGMAVIAPVLFVF 172
pfam05231    99 GRHRLQLLFWLRFLLAAAIIAALLLAIIGLALLLLLGLLPlapFAESWLTWWLGSATGVLVLAPLLLLL 167

cl01367

120595

MASE1

-1

33250

COG3447

Predicted integral membrane sensor domain [Signal transduction mechanisms]

false

308

2e-07

52.20

53.25

4,25,32,75,100,111,14,117,125,24,141,151,45

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869  26 GLTLTRGEDRVAAIWLSNGVLVVLLLSKGKTPTLPLVMIGFLANLLANRVAGDQWLQASSLAAINALEVVIAYAL----L 101
COG3447      33 SLELSQFGTQLAPLWFPTSIMMGAFYRHAGRMWPGIALSCSLGNIAASILLFSTSSLNMAITTINILEAVVGAVLlrklL 112

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 102 TRRGREVDLRDPSglgRFVLWGAIVAPLICSLLGTTVVVA--SRGGDFQATLRVWFLADALGMAVIAPVLFVFLKDHVLT 179
COG3447     113 PWYNPLQNLQDWL---RFLLGGAIVPPLLGAIIGSVLLVVlgTPGDDFSEAWFTWWLGDAIGILALAPLGIVIRPNWLRR 189


                ....*..
gi 94970869 180 ELFGREK 186
COG3447     190 HRLLRLQ 196

cl01367

120595

MASE1

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

5e-39

157.00

38.85

4,294,263,76,371,339,45,416,385,21,438,406,26

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 295 ERLTGLVYVDWLTDLPNRRHFDMRFNSEWRRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCLAKLGSVMAASVkRSA 374
COG3706     264 ERLQELALVDGLTGLFNRRYFDEHLADLWKRALREGRPLSLLMLDIDDFKEINDTYGHDVGDEVLRQVARRLRQTV-RGL 342

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 375 DFVARYGGEEFVVILPETTATGAGIVAANVMEAVAALELPHA-GSPHKQVSVSVGIAYAHPDIGaEPSELVRSADRALYT 453
COG3706     343 DLVARYGGEEFAVVLPDTDLEAAIAIAERIRQKINELPFVHElSREPLEVTISIGVAEGKPGED-SIEELLKRADKALYK 421

                       170
                ....*....|.
gi 94970869 454 AKRDGRNCVRV 464
COG3706     422 AKASGRNRVVV 432

-1

137400

PRK09581

pleD

response regulator PleD; Reviewed

false

true

false

457

4e-34

140.82

34.57

6,303,294,67,371,361,38,409,401,12,422,413,8,430,422,4,436,426,26

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 304 DWLTDLPNRRHFDMRFNSEWRRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCLAKLGSVMAASVkRSADFVARYGGE 383
PRK09581    295 DGLTGLHNRRYFDMHLKQLIERANERGKPLSLMMLDIDHFKQVNDTYGHDAGDEVLREFAKRLRKNI-RGTDLIARYGGE 373

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 384 EFVVILPETTATGAGIVAANVMEAVA--ALELPHAGSPHKqVSVSVGIA-YAHPdiGAEPSELVRSADRALYTAKRDGRN 460
PRK09581    374 EFVVVMPDTDIEVAIAVAERIRRKIAeePFAISDGKERLN-VTVSIGVAeLRPS--GESIEALIKRADKALYEAKNTGRN 450


                ..
gi 94970869 461 CV 462
PRK09581    451 RV 452

-1

137576

PRK09894

hypothetical protein; Provisional

false

true

false

293

8e-31

130.21

57.68

5,293,122,29,324,151,46,371,197,47,419,244,15,436,259,32

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 294 HERLTGLVYVDWLTDLPNRRHFDMRFNSEwrRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCLAKLGSVMAASVkRS 373
PRK09894    123 IYLLTIRSNMDVLTGLPGRRVLDESFDHQ--LRNREPLNLYLALLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWT-RP 199

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 374 ADFVARYGGEEFVVILPETTATGAGIVAANVMEAVAALELPHAGSpHKQVSVSVGIAYAHPdiGAEPSELVRSADRALYT 453
PRK09894    200 YETVYRYGGEEFIIILKAATDEEACRAGERIRQLIANQAITHSEG-RINITATFGVTRAFP--EEPLDEVIGRADRAMYE 276

                       170
                ....*....|....*
gi 94970869 454 AKRDGRNCVRVALEQ 468
PRK09894    277 GKQAGRNRVMFIDEQ 291

-1

137770

PRK10245

adrA

diguanylate cyclase AdrA; Provisional

false

true

false

371

1e-23

106.13

48.25

5,279,191,13,295,204,75,371,279,43,416,322,21,438,343,27

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 280 SFPLAAVLGERDRlheRLTGLVYVDWLTDLPNRRHFDMRFNSEWRRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCL 359
PRK10245    192 SYQTATKLAEHKR---RLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAI 268

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 360 AKLGSVMAASVkRSADFVARYGGEEFVVILPETTATGAGIVAANVMEAVAALELPhaGSPHKQVSVSVGIAYAHPDIGaE 439
PRK10245    269 VALTRQLQITL-RGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLP--NAPQVTLRISVGVAPLNPQMS-H 344

                       170       180
                ....*....|....*....|....*.
gi 94970869 440 PSELVRSADRALYTAKRDGRNCVRVA 465
PRK10245    345 YREWLKSADLALYKAKKAGRNRTEVA 370

-1

137662

PRK10060

RNase II stability modulator; Provisional

false

true

false

663

6e-22

100.57

25.64

7,288,224,33,325,257,7,332,266,30,363,296,43,409,339,5,414,345,17,432,362,32

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 289 ERDRLHERLTGLVYVDWLTDLPNRRHFDMRFNSewrrAMRSRMP--ISLMMIDVDQFKEYNDAYGHMAGDRCLAKLgSVM 366
PRK10060    225 EERRAQERLRILANTDSITGLPNRNAIQELIDH----AIAQADNnqVGIVYLDLDNFKKVNDAYGHMFGDQLLQDV-SLA 299

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 367 AASVKRSADFVARYGGEEFVVILPETTATGAGIVAANVMEavaALELP-HAGSPHKQVSVSVGIAYaHPDIGAEPSELVR 445
PRK10060    300 ILSCLEEDQTLARLGGDEFLVLASHTSQAALEAMASRILT---RLRLPfRIGLIEVYTGCSIGIAL-SPEHGDDSESLIR 375

                       170
                ....*....|....*....
gi 94970869 446 SADRALYTAKRDGRNCVRV 464
PRK10060    376 SADTAMYTAKEGGRGQFCV 394

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

4e-19

91.31

14.16

4,303,690,67,371,757,50,422,807,8,431,815,33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869  304 DWLTDLPNRRHFDMRFNSEWRRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCLAKLGSVMAASVkRSADFVARYGGE 383
PRK09776     691 DALTGLANRASFEKQLREALQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALLRELASLMLSML-RSSDVLARLGGD 769

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869  384 EFVVILPETTATGAGIVAANVMEAVAALELPHAGSPHKqVSVSVGIAyAHPDIGAEPSELVRSADRALYTAKRDGRNCVR 463
PRK09776     770 EFGLLLPDCNVESARFIATRIISAINDYRFPWEGRVYR-VGASAGIT-AIDDNNHQASEVMSQADIACYAAKNAGRGRVT 847


                 .
gi 94970869  464 V 464
PRK09776     848 V 848

-1

34606

COG5001

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF...

false

true

false

663

4e-19

90.85

29.86

6,265,190,7,272,199,102,375,301,20,397,321,17,414,339,18,433,357,31

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 266 VLLLQAY--LACVVATSFPLAAVLGERDRLHERLTGLVYVDWLTDLPNRRHFDMRFNSEWRRAMRSRMPISLMMIDVDQF 343
COG5001     191 VILLTNYreFSDMVQSQVTLTQRAEETRRLSDENDRLANLDSLTGLPNRRRFFAELDARLAAARQSGRRLVLGVIDLDGF 270

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 344 KEYNDAYGHMAGDRCLAKLGSVMAASVKRSAdFVARYGGEEFVVILPETTATgaGIVAANVMEAVAALELP-HAGSPHKQ 422
COG5001     271 KPVNDAFGHATGDRLLIEVGRRLKAFDGAPI-LAARLGGDEFALIIPALEDD--ALRVAGARALCESLQAPyDLRGVRVQ 347

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 94970869 423 VSVSVGIAYAhPDIGAEPSELVRSADRALYTAKRDGRNCVRV 464
COG5001     348 VGASIGIAPF-PSGADTSEQLFERADYALYHAKQNGKGAAVL 388

-1

138538

PRK11359

cAMP phosphodiesterase; Provisional

false

true

false

799

4e-12

67.94

22.53

7,270,345,42,312,391,14,334,405,37,372,442,31,404,473,16,421,489,10,434,499,26

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 271 AYLACVVATSFPLAAVLGERDRLHERLTGLVYVDWLTDLPNR----RHFDMRFNSEWRRAmrsrmpisLMMIDVDQFKEY 346
PRK11359    346 AFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRnnlhNYLDDLVDKAVSPV--------VYLIGVDHIQDV 417

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 347 NDAYGHMAGDRCLAKLGSVMAASVKrSADFVARYGGEEFVVILPETTATGAGIVAANvMEAVAALELPHAGSPHkQVSVS 426
PRK11359    418 IDSLGYAWADQALLEVVNRFREKLK-PDQYLCRIEGTQFVLVSLENDVSNITQIADE-LRNVVSKPIMIDDKPF-PLTLS 494

                       170       180       190
                ....*....|....*....|....*....|....
gi 94970869 427 VGIAYahpDIGAEPSELVRSADRALYTAKRDGRN 460
PRK11359    495 IGISY---DVGKNRDYLLSTAHNAMDYIRKNGGN 525

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

8e-11

63.57

14.07

6,25,34,18,43,54,21,66,75,31,98,106,5,103,113,26,132,139,52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869   26 GLTLTRGEDRVAAIWLSN--GVLVVLLLSKGKTPTLPLVMIgfLANLLANRVAGDQWLQASSLAAINALEVVIAyALLTR 103
PRK09776      35 SLELSRFPTTLAPLWFPTaiMMVAFLRHPGRMWPGILLSCS--LGNIAANILLFSTSSLNLTWTTINLVEAVVG-AVLLR 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869  104 --RGREVDLRDPSGLGRFVLWGAIVAPLicsLLGTTVVVASRGGDFQATLRVWFLADALGMAVIAPVLFVFLKDHVLTEL 181
PRK09776     112 klLPWYNPLQNLADWLRLALGSAIVPPL---LGGALVVLLTPGDDFLRAWLIWVLSEAIGMLALVPLGLLFKPHYLLRHR 188


                 ...
gi 94970869  182 FGR 184
PRK09776     189 NPR 191

-1

137615

PRK09966

hypothetical protein; Provisional

false

true

false

407

2e-07

52.33

37.59

8,289,245,12,310,257,10,321,267,42,370,309,6,376,321,13,389,336,24,414,360,3,420,363,35

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 290 RDRLHERLTGLVyvdwltdlpNRRHFDMRFNsEWRRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCLAKLGsvmaas 369
PRK09966    246 RTALHDPLTGLA---------NRAAFRSGIN-TLMNNSDARKTSALLFLDGDNFKYINDTWGHATGDRVLIEIA------ 309

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 370 vKRSADF------VARYGGEEFVVIL--PETTATGAGIVAANVMEAVAALELpHAGsphKQVSVSVGIAYAHPDIGAEPS 441
PRK09966    310 -KRLAEFgglrhkAYRLGGDEFAMVLydVQSESEVQQICSALTQIFNLPFDL-HNG---HQTTMTLSIGYAMTIEHASAE 384

                       170
                ....*....|....
gi 94970869 442 ELVRSADRALYTAK 455
PRK09966    385 KLQELADHNMYQAK 398

-1

138376

PRK11059

regulatory protein CsrD; Provisional

false

true

false

642

7e-07

50.65

24.14

5,302,229,75,377,305,42,419,351,1,426,352,8,436,360,24

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 303 VDWLTDLPNRRHFDMRFNSEWRRAMRSRMPISLMMIDVDQFKEYNDAYGHMAGDRCLAKLGSVMAASVKRSADFV-ARYG 381
PRK11059    230 LDAKTGLGNRLFFDNQLDTLLEDQEKVGAHGVVMLIRLPDFDLLQEELGESQVDELLFELINLLSTFVQRYPGALlARYS 309

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94970869 382 GEEFVVILPETTATGAGIVAANVMEAVAALELPHAGSP----HkqvsvsVGIAYAHPdiGAEPSELVRSADRALYTAKRD 457
PRK11059    310 RSDFAVLLPHRSLKEADSLASQLLKAVDSLPPPKMLDRddflH------IGIAAYRS--GQSTEQVMEEAEMALRSAQLQ 381


                ...
gi 94970869 458 GRN 460
PRK11059    382 GGN 384

-1

active site	0	10	10	true	133472	cd01949	GGDEF
I-site	1	3	3	true	133472	cd01949	GGDEF