NCBI Conserved Domain Search

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Conserved domains on [gi\|94967406\|ref\|YP_589454.1\|]
periplasmic sensor signal transduction histidine kinase [Candidatus Koribacter versatilis Ellin345]

Graphical summary show options »	Show site features Horizontal zoom: ×	?



List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

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of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

28956

cd00075

HATPase_c

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for...

true

false

true

103

6e-13

70.73

100.00

5,384,0,22,413,22,23,436,47,10,446,61,33,480,94,9

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 385 LEQMMINLVKNAVEASKEMQQPetpeppeVIVGWDAEPAAIILKVEDNGPGI--MNPSNAFVPF----YTTKQGGSGIGL 458
cd00075       1 LQQVLLNLLSNAIKHTPEGGGR-------ITISVERDGDHLEIRVEDNGPGIpeEDLERIFERFsdgsRSRKGGGTGLGL 73

                        90       100       110
                ....*....|....*....|....*....|.
gi 94967406 459 VLSRQIAEAHGGRLELINREGtRGCMARVTL 489
cd00075      74 SIVKKLVELHGGRIEVESEPG-GGTTFTITL 103

cl00075

140416

HATPase_c

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for...

128669

smart00387

HATPase_c

Histidine kinase-like ATPases

false

111

3e-19

91.56

98.20

5,379,0,26,413,26,23,436,51,15,451,71,28,480,99,10

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 380 ADPDQLEQMMINLVKNAVEASKEMQQpetpeppeVIVGWDAEPAAIILKVEDNGPGI--MNPSNAFVPFYTTKQ-----G 452
smart00387    1 GDPDRLRQVLSNLLDNAIKYTPEGGR--------ITVTLERDGDHLEITVEDNGPGIppEDLEKIFEPFFRTDGrsrkiG 72

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 94967406 453 GSGIGLVLSRQIAEAHGGRLELINREGtRGCMARVTLP 490
smart00387   73 GTGLGLSIVKKLVELHGGEISVESEPG-GGTTFTITLP 109

cl00075

140416

HATPase_c

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for...

-1

111420

pfam02518

HATPase_c

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase

false

111

9e-17

83.53

98.20

5,379,0,26,413,26,23,436,51,11,447,67,32,480,99,10

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 380 ADPDQLEQMMINLVKNAVEASKEMQQpetpeppeVIVGWDAEPAAIILKVEDNGPGI--MNPSNAFVPFY-----TTKQG 452
pfam02518     1 GDEDRLRQVLSNLLDNAIKHAPAGGE--------ITVTLEREGGRLRITVEDNGPGIppEDLEKIFEPFYrdgsdSRKVG 72

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 94967406 453 GSGIGLVLSRQIAEAHGGRLELINREGtRGCMARVTLP 490
pfam02518    73 GTGLGLSIVKKLVELHGGTITVESEPG-GGTTFTLTLP 109

cl00075

140416

HATPase_c

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for...

-1

34605

COG5000

NtrY

Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms]

Signal transduction histidine kinase involved in nitrogen fixation and metabolism...

true

false

712

3e-37

151.65

59.83

9,87,285,17,106,302,74,180,383,74,254,467,52,308,519,49,357,574,17,375,591,37,413,628,23,436,653,58

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406  88 IALLAGESIAWLLLVLAqhEQIVRPLQTLTNVVAALREEDYSFRARGAAMDDALGELAIEVNALADVLTIQKTSAIEATA 167
COG5000     286 TALLVLLAAIWTAIAFA--RRIVRPIRKLIEAADEVADGDLDVQVPVRRVDEDVGRLSKAFNKMTEQLSSQQEALERAKD 363

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 168 LLSRIVEEIDAPL-------FAFDPEHKLKLVNSAGERLLQQPATKLLGSTATELNLQVAFEAESESLVPLPYSPNSRWM 240
COG5000     364 ALEQRRRFLEAVLsgltagvIGFDNRGCITTVNPSAEQILGKPFDQLLGQSLSAIAPELEEVFAEAGAAARTDKRVEVKL 443

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 241 VRRSSFRQDGVPHT----------LIVLSDVSRALREEERSAWQKLIRVLGHELNNSLAPIKSIAGSLNSRLKRTSlsDE 310
COG5000     444 AREGEERTLNVQATrepedngngyVVTFDDITDLVIAQRSAAWGDVARRIAHEIKNPLTPIQLSAERLLRKLGKEI--DE 521

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 311 EREDFEKGLSIVEGRAESLNRFLQAYRQLATMPPPKLKLVSMKSLVE------RVAGLETRVVVEVRNNPdVHLQADPDQ 384
COG5000     522 DREVFDRCTDTIIRQVEDIKRMVDEFRAFARMPAPKLEKSDLRALLKevsflyEIGNDHIVFAAEFGGEP-LIGMADATL 600

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 385 LEQMMINLVKNAVEASKEMQQPETPEPPeVIVGWDAEPAAIILKVEDNGPGI--MNPSNAFVPFYTTKQGGSGIGLVLSR 462
COG5000     601 LGQVFGNLLKNAAEAIEAVEAEERRTAL-IRVSLDDADGRIVVDVIDNGKGFprENRHRALEPYVTTREKGTGLGLAIVK 679

                       410       420       430
                ....*....|....*....|....*....|..
gi 94967406 463 QIAEAHGGRLELINREGTRGCMARVTLPRGRD 494
COG5000     680 KIVEEHGGRLELHNAPDFDGAMIRIKFPLKEL 711

-1

138539

PRK11360

sensory histidine kinase AtoS; Provisional

false

true

false

607

3e-26

115.17

68.70

15,79,182,9,88,193,18,110,211,45,162,256,36,198,300,44,242,347,8,250,358,31,281,396,5,289,401,24,318,425,41,359,472,19,378,492,21,406,513,33,439,548,41,481,589,10

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406  80 QKWTIDAKI--ALLAGESIAWLLLVLAQHeqivRPLQTLTNVVAALREEDYSFRARGAAMDDALGELAIEVNALADVLti 157
PRK11360    183 QAWKMDVRIyiVLTAGLVIGLLLIVLLSR----RLSANVDIITDGLSTLEQDLPTRLPPLPGELGQISQAINNLAQAL-- 256

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 158 qktsaIEATALLSRIVEEIDAPLFAFDPEHKLKLVNSAGER--------LLQQPATKLLGSTATELNLQVAFEAESESLV 229
PRK11360    257 -----REARTLNELIIENAADGIIAIDRQGDITTMNPAAEVitgyqrheLVGQPYSMLFDNTQFYSPVLDTLEHGTEHVA 331

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 230 PLPYSPNSRWMVR---RSSFRQDG---VPHTLIVLSDVSRALREEERSAWQKLIRVLG-------HELNNslaPIKSIAG 296
PRK11360    332 LEISFPGRDRTIElsvTTSRLHDThgeMIGAVVIFSDLTARKRLQRRMARAERLAALGelmagvaHEIRN---PLTAIRG 408

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 297 SLNSRLKRTSLSDEEREdfekgLSIVEGRAESLNRFLQAYRQLATMPPPKLKLVSMKSLVERV------AGLETRVVVEV 370
PRK11360    409 YVQILRQQTSDPIHQEY-----LSVVLREVDSLNKVIQQLLEFSRPRHSQWQQVSLNALVEEVlvlvqtAGVQARVDFIT 483

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 371 RNNPDVHL-QADPDQLEQMMINLVKNAVEAskemqqpETPEPPEVIVGWDAEPAAIILKVEDNGPGIMNP--SNAFVPFY 447
PRK11360    484 ELDNELPPiNADRELLKQVLLNILINAVQA-------ISARGKIRIRTWQYSDSQQAISIEDNGCGIDLEllKKIFDPFF 556

                       410       420       430       440
                ....*....|....*....|....*....|....*....|....
gi 94967406 448 TTKQGGSGIGLVLSRQIAEAHGGRLELINREGTrGCMARVTLPR 491
PRK11360    557 TTKASGTGLGLALSQRIINAHQGDIRVASLPGY-GTTFTLILPI 599

-1

33642

COG3852

NtrB

Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]

false

true

false

363

5e-18

87.66

91.74

11,171,11,44,215,61,11,226,81,49,275,134,20,300,154,17,320,171,39,359,215,17,376,233,23,399,262,37,438,299,3,441,306,38

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 172 IVEEIDAPLFAFDPEHKLKLVNSAGERLLQQPATKLLGSTATEL------NLQVAFEAESE---------SLVPLPYSPN 236
COG3852      12 ILNNLINPVLLVDDELAIHYANPAAEQLLAVSARRLAGTRLSELlpfgslLLSLLDQVLERgqpvteyevTLVILGRSHI 91

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 237 SRWMVRRSSFRQDGVPHTLIVLSDVSRALREEERSAWQK----LIRVLGHELNNSLAPIKSIAgslnsRLKRTSLSDEER 312
COG3852      92 VDLTVAPVPEEPGSVLLEFHPRDMQRRLDREQTQHAQQRavkgLVRGLAHEIKNPLGGIRGAA-----QLLERALPDEAL 166

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 313 EDFEKglsIVEGRAESLNRFLQAYRQLATMPPPKLKLVSMKSLVERV-----AGLETRVVVEVRNNPDV-HLQADPDQLE 386
COG3852     167 RELTQ---LIIEEADRLRNLVDRLEVLGPQRPGDRVPVNIHEVLERVralveAEFADNVRLIRDYDPSLpEVLGDRDQLI 243

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 387 QMMINLVKNAVEA------SKEMQQPETPEPPEVIVGWDAEPAAIILKVEDNGPGImnPSN----AFVPFYTTKQGGSGI 456
COG3852     244 QVFLNLVRNAAQAlggradEGGEIILRTRTGIQLTIAGTRYRLALPLEVIDNGPGV--PPDlqdhLFYPMVSGREGGTGL 321

                       330       340
                ....*....|....*....|...
gi 94967406 457 GLVLSRQIAEAHGGRLELINREG 479
COG3852     322 GLALAQNLIDQHGGKIEFDSWPG 344

-1

30987

COG0642

BaeS

Signal transduction histidine kinase [Signal transduction mechanisms]

false

true

false

336

4e-17

84.84

68.45

8,257,99,42,308,141,34,342,180,20,362,206,42,413,248,23,436,273,16,452,291,27,480,318,11

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 258 LSDVSRALREEERSAWQKLIRVLGHELNNSLAPIKSIAGSLNsrlkrtslsDEEREDFEKGLSIVEGRAESLNRFLQAYR 337
COG0642     100 LNELLERLERLLRRAKREFLANISHELRTPLTAIRGLLELLL---------EGLLDPQRELLEIIEEEAERLLRLVNDLL 170

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 338 QLATM-----PPPKLKLVSMKSLVERVAGL------ETRVVVEVRNNPDVHLQADPDQLEQMMINLVKNAVEASKEMQqp 406
COG0642     171 DLSRLeagtkLKLLLELVDLAELLEEVVRLlaplaqEKGIELAVDLPELPYVLGDPERLRQVLVNLLSNAIKYTPGGE-- 248

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 407 etpeppeVIVGWDAEPAAIILKVEDNGPGI--MNPSNAFVPFYTTKQG--GSGIGLVLSRQIAEAHGGRLELINREGtRG 482
COG0642     249 -------ITISVRQDDEQVTISVEDTGPGIpeEELERIFEPFFRTDKSrsGTGLGLAIVKRIVELHGGTISVESEPG-KG 320


                ....*....
gi 94967406 483 CMARVTLPR 491
COG0642     321 TTFTIRLPL 329

-1

33974

COG4251

Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms]

Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal...

false

true

false

750

2e-16

82.68

31.60

10,257,506,14,271,522,35,308,557,37,346,594,15,361,610,5,366,618,34,407,652,32,439,686,8,447,698,32,480,730,13

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 258 LSDVSRALREEERS--AWQKLIRVLGHELNNSLAPIKSIAGSLNSRLKRTSlsDEEREDFEKGLSIVEGRAESLNRFLQA 335
COG4251     507 AEELAQLRRELERSnaELRAFAYVASHDLQEPLRQISNYAQLLSERYSDAL--DEEAKEFITFISRLTSLMQQLIDDLLT 584

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 336 YRQLATMPPPkLKLVSMKSLVERVAG-LETRV---VVEVRNNPDVHLQADPDQLEQMMINLVKNAVEASkemqqpeTPEP 411
COG4251     585 YSKLGLTEAP-LQPTDVQKVVDKVLLeLSQRIadtGAEIRIAPLPVVAADATQLGQVFQNLIANAIKFG-------GPEN 656

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 412 PEVIVGWDAEPAAIILKVEDNGPGIMNP--SNAFVPFY----TTKQGGSGIGLVLSRQIAEAHGGRLELINREGtRGCMA 485
COG4251     657 PDIEISAERQEDEWTFSVRDNGIGIDPAyfERIFVIFQrlhsRDEYLGTGLGLAICKKIAERHQGRIWVESTPG-EGSTF 735


                ....*...
gi 94967406 486 RVTLPRGR 493
COG4251     736 YFTLPVGG 743

-1

33926

COG4191

Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms]

Signal transduction histidine kinase regulating C4-dicarboxylate transport system [...

false

true

false

603

6e-16

80.70

34.99

8,279,390,28,312,418,45,357,471,13,371,484,30,407,514,32,439,548,15,454,565,25,480,590,11

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 280 LGHELNNSLAPIKSIAGSLNSRLKRTSLsdeerEDFEKGLSIVEGRAESLNRFLQAYRQLATMPPPKLKLVSMKSLVE-- 357
COG4191     391 IAHELNQPLAAIRTYADNARLLLERGRT-----EEARENLERISALTERMAAITAHLKSFARKSRDAAGPVSLREAIEga 465

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 358 ------RVAGLETRVVVEVrNNPDVHLQADPDQLEQMMINLVKNAVEASKemqqpeTPEPPEVIVGWDAEPAAIILKVED 431
COG4191     466 lellrgRLRAAGVELELDL-PDAPLWVMANEIRLEQVLVNLLQNALDAMA------GQEDRRLSIRAQREGGQVVLTVRD 538

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 94967406 432 NGPGIMNP--SNAFVPFYTTKQGGS--GIGLVLSRQIAEAHGGRLELINREGtRGCMARVTLPR 491
COG4191     539 NGPGIAPEalPHLFEPFFTTKPVGKglGLGLAISQNIARDLGGSLEVANHPE-GGASFTIELRR 601

-1

34607

COG5002

VicK

Signal transduction histidine kinase [Signal transduction mechanisms]

false

true

false

459

8e-16

80.36

89.54

20,89,36,16,107,52,29,137,81,20,157,102,21,179,123,35,214,159,8,222,171,24,246,199,10,256,210,6,262,217,8,273,225,21,294,251,33,328,284,12,340,297,24,365,321,9,374,332,26,408,358,32,440,392,7,447,405,25,473,430,17

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406  90 LLAGESIAWLLLVLAQheQIVRPLQTLTNVVAALREEDYSFRARGAAmDDALGELAIEVNALADVLTI-QKTSAIEATAL 168
COG5002      37 LIALIITALLGILLAR--TITKPITDMRKQAVDMARGNYSRKVKVYG-TDEIGELADSFNDLTKRVQEaQANTEQERRKL 113

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 169 LSRIVEEIDApLFAFDPEHKLKLVNSAGERLLQQPATKLLGSTATE-LNLQVAFE----AESESLVPLPYSPNSRWMVRR 243
COG5002     114 DSVLAYMTDG-VIATDRRGKIILINKPALKMLGVSKEDALGRSILElLKIEDTYTfedlVEKNDSLLLDSSDEEEGYVLR 192

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 244 SSF----RQDGVPHTLI-VLSDVS-RALREEERsawQKLIRVLGHELNNSLAPIKSI-----AGSLNSRLKRTSLSDEER 312
COG5002     193 VNFsviqRESGFISGLIaVLHDVTeQEKVERER---REFVANVSHELRTPLTSMKSYlealeEGAWEDKEIAPRFLRVTL 269

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 313 EDFEKGLSIVEGRAEsLNRFLQAYRQLA-TMPPPKLKLVSMKSLVERVAGLETrVVVEVRNNP--DVHLQADPDQLEQMM 389
COG5002     270 NETERMIRLVNDLLQ-LSRMDNARYQLNkEWINFTAFLNEIINRFEMILKKET-IARFVRDIPkqDIWVEIDPDKMTQVL 347

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 390 INLVKNAVEASkemqqpetPEPPEVIVGWDAEPAAIILKVEDNGPGIMNPS--NAFVPFY------TTKQGGSGIGLVLS 461
COG5002     348 DNIISNALKYS--------PDGGRITVSVKQRETWVEISISDQGLGIPKEDleKIFDRFYrvdkarSRKMGGTGLGLAIA 419

                       410       420
                ....*....|....*....|....*....
gi 94967406 462 RQIAEAHGGRLeLINREGTRGCMARVTLP 490
COG5002     420 KEIVQAHGGRI-WAESEEGKGTTFSFTLP 447

-1

32387

COG2205

KdpD

Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]

false

true

false

890

5e-15

77.59

25.39

13,262,652,10,275,662,23,300,685,15,318,700,14,332,718,24,356,746,22,378,769,29,414,798,7,422,805,14,438,819,4,442,827,6,448,837,31,480,868,10

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 263 RALREEERSAwqkLIRVLGHELNNSLAPIKSIAGSLnsRLKRTSLSDEEREDFekgLSIVEGRAESLNRF----LQAYRQ 338
COG2205     653 AAERERLRSA---LLASISHDLRTPLTAIMGAAETL--LLDGEALSPEDRAEL---LSSIREESERLTRLvtnlLDMTRL 724

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 339 LATMPPPKLKLVSMKSLV----ERVAGLETRVVVEVRNNPDVHL-QADPDQLEQMMINLVKNAVEASKEMQQPEtpeppe 413
COG2205     725 QSGGVNLKLDWVLVEEVVgealQRLRKRFTGHKIVVSVPVDLPLiHVDSPLIEQVLINLLENALKYAPPGSEIR------ 798

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 414 vIVGWDAEpAAIILKVEDNGPGImnPSNA----FVPFYT----TKQGGSGIGLVLSRQIAEAHGGRLELINREGtRGCMA 485
COG2205     799 -INAGVER-ENVVFSVIDEGPGI--PEGEleriFDKFYRgnkeSATRGVGLGLAICRGIVEAHGGTISAENNPG-GGAIF 873


                ....*
gi 94967406 486 RVTLP 490
COG2205     874 VFTLP 878

-1

138403

PRK11100

sensory histidine kinase CreC; Provisional

false

true

false

475

4e-13

71.04

45.47

13,276,259,13,292,272,5,299,277,44,343,322,15,358,338,7,365,350,7,373,357,27,410,384,14,424,400,12,438,412,4,442,420,6,448,431,32,481,463,12

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 277 IRVLGHELNNSLApikSIAGSlnSRLKRTSLSDEEREDFEKGLSIVEGRAESLNRFLQAYRQLATMP-PPKLKLVSMKSL 355
PRK11100    260 VQTLTHELKSPLA---AIRGA--AELLQEDPPPEDRQRFTGNILAQSARLQQLIDRLLELARLEQRQeLEVLEPVALAAL 334

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 356 VER-VAGLETR-----VVVEVRNnPDVHLQADPDQLEQMMINLVKNAVEASkemqqpetpePPEVIVGWDAEPAA--IIL 427
PRK11100    335 LEElVEAREAQaaakgITLRLRP-DDAAVLGDPFLLRQALGNLLDNAIDFT----------PEGGTITLSAERDGeqVAL 403

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 94967406 428 KVEDNGPGImnPSNA----FVPFYT-----TKQGGSGIGLVLSRQIAEAHGGRLELINREGTrGCMARVTLPRGR 493
PRK11100    404 SVEDSGPGI--PDYAlpriFERFYSlprpaNGRKSTGLGLAFVREVARLHGGEVTLRNRPEG-GVLATLTLPRHF 475

-1

131962

TIGR02916

PEP_his_kin

putative PEP-CTERM system histidine kinase

false

true

false

679

5e-13

70.91

20.18

7,349,542,10,359,556,11,372,567,28,408,595,28,439,623,5,444,634,35,480,669,10

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 350 VSMKSLVERV----AGLETRVVVEVrnNPDVHLQADPDQLEQMMINLVKNAVEASkemqqpetPEPPEVIVGWDAEPAAI 425
TIGR02916   543 VDLVDLLRRAiaskRAQGPRPEVSI--DTDLSVRADRERLERVLGHLVQNALEAT--------PGEGRVAIRVERECGAA 612

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 94967406 426 ILKVEDNGPGImnpSNAFV------PFYTTKQGGSGIGLVLSRQIAEAHGGRLELINREGtRGCMARVTLP 490
TIGR02916   613 RIEIEDSGCGM---SPAFIrerlfkPFDTTKGAGMGIGVYECRQYVEEIGGRIEVESTPG-QGTIFTLVLP 679

-1

138388

PRK11073

glnL

nitrogen regulation protein NR(II); Provisional

false

true

false

348

3e-12

68.21

90.23

13,183,23,26,212,49,47,259,111,9,268,125,40,315,165,8,324,173,10,336,183,26,362,214,14,376,229,38,414,271,12,427,283,9,438,292,3,441,299,38

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 184 DPEHKLKLVNSAGERLLQQPATKLLGstaTELNLQVAFEAESESLVPLPYSPNSRWMVRRSSFRQDGVPHTLIVLS---- 259
PRK11073     24 DDNLAIHYANPAAQQLLAQSSRKLFG---TPLPELLSYFSLNIELMQESLQAGQGFTDNEVTLVIDGRSHILSLTAqrlp 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 260 -----------DVSRALREE-----ERSAWQKLIRVLGHELNNSLAPIKSIAGSLNSRLKRTSLSdeeredfEKGLSIVE 323
PRK11073    101 egmillemapmDNQRRLSQEqlqhaQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALT-------EYTKVIIE 173

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 324 gRAESLNRFLQayRQLATMPPPKLKLVSMKSLVERVAGL-----ETRVVVEVRNNPDV-HLQADPDQLEQMMINLVKNAV 397
PRK11073    174 -QADRLRNLVD--RLLGPQRPGTHITESIHKVAERVVQLvslelPDNVRLIRDYDPSLpELAHDPDQIEQVLLNIVRNAL 250

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 398 EASKEMQQPETPEPPEV----IVGWDAEPAAIIlKVEDNGPGImnPSN----AFVPFYTTKQGGSGIGLVLSRQIAEAHG 469
PRK11073    251 QALGPEGGEITLRTRTAfqltLHGERYRLAARI-DIEDNGPGI--PPHlqdtLFYPMVSGREGGTGLGLSIARNLIDQHS 327

                       330
                ....*....|
gi 94967406 470 GRLELINREG 479
PRK11073    328 GKIEFTSWPG 337

-1

132011

TIGR02966

phoR_proteo

phosphate regulon sensor kinase PhoR

false

true

false

333

5e-11

64.54

97.30

17,166,2,12,178,17,45,223,68,6,229,75,17,249,92,17,266,110,4,273,114,12,288,126,25,316,151,26,342,181,17,359,206,17,378,223,19,405,242,31,439,273,6,445,284,2,447,292,26,474,318,8

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 167 ALLSRIVEEIDA---PLFAFDPEHKLKLVNSAGERLLQQPATKLLGSTATELNLQVAFEA------ESESLV-PLPYSPN 236
TIGR02966     3 ALLSRFRAAAQAlpdAVVVLDEEGQIEWCNPAAERLLGLRWPDDLGQRITNLIRHPEFVEylaagrFSEPLElPSPINSE 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 237 SRWMVRRSSFrqdGVPHTLIVLSDVSRALR-EEERsawQKLIRVLGHELNnslAPIKSIAGSLNSRLKRTSLSDEEREdf 315
TIGR02966    83 RVLEIRIAPY---GEEQKLLVARDVTRLRRlEQMR---RDFVANVSHELR---TPLTVLRGYLETLADGPDEDPEEWN-- 151

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 316 eKGLSIVEGRAESLNRFLQAYRQLATM----PPPKLKLVSMKSLVERV--------AGLETRVVVEVRNNPDVhlQADPD 383
TIGR02966   152 -RALEIMLEQSQRMQSLVEDLLTLSRLesaaSPLEDEPVDMPALLDHLrdeaealsQGKNHQITFEIDGGVDV--LGDED 228

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 384 QLEQMMINLVKNAVeaskemqqPETPEPPEVIVGWDAEPAAIILKVEDNGPGImnpSNAFVP-----FY------TTKQG 452
TIGR02966   229 ELRSAFSNLVSNAI--------KYTPEGGTITVRWRRDGGGAEFSVTDTGIGI---APEHLPrlterFYrvdksrSRDTG 297

                       330       340       350
                ....*....|....*....|....*....|
gi 94967406 453 GSGIGLVLSRQIAEAHGGRLElINREGTRG 482
TIGR02966   298 GTGLGLAIVKHVLSRHHARLE-IESELGKG 326

-1

137849

PRK10364

sensor protein ZraS; Provisional

false

true

false

455

4e-10

61.48

45.71

6,265,230,52,324,282,41,365,329,11,376,341,23,407,364,33,440,399,39

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 266 REEERSAWQKLIRVLGHELNNSLAPIKSIAGSLNSRLKRTSLSDEEREDFEKglsivegRAESLNRFLQAYRQLATMPPP 345
PRK10364    231 RKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAK-------EADRLNRVVSELLELVKPTHL 303

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 346 KLKLVSMKSLVERVAGLETR------VVVEVRNNPDV-HLQADPDQLEQMMINLVKNAVEAskemqqpeTPEPPEVIVGW 418
PRK10364    304 ALQAVDLNTLINHSLQLVSQdansreIQLRFTANDTLpEIQADPDRLTQVLLNLYLNAIQA--------IGQHGVISVTA 375

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 94967406 419 DAEPAAIILKVEDNGPGIMNPS--NAFVPFYTTKQGGSGIGLVLSRQIAEAHGGRLELINREG 479
PRK10364    376 SESGAGVKISVTDSGKGIAADQleAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEG 438

-1

138144

PRK10755

sensor protein BasS/PmrB; Provisional

false

true

false

355

6e-09

57.39

31.83

5,373,242,27,408,269,17,426,286,13,439,304,7,447,311,44

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 374 PDVHLQADPDQLEQMMINLVKNAVEASkemqqpetPEPPEVIVGWDAEPAAIiLKVEDNGPGIMNP-----SNAFVPFyT 448
PRK10755    243 ADITVQGDATLLRLLLRNLVENAHRYS--------PEGSNITIKLQEDGGAV-MAVEDEGPGIDESkcgelSKAFVRM-D 312

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 94967406 449 TKQGGSGIGLVLSRQIAEAHGGRLELINREGTRGCMARVTLPR 491
PRK10755    313 SRYGGIGLGLSIVSRITQLHHGQFFLQNRQERSGTRAWVWLKK 355

-1

139897

PRK13837

two-component VirA-like sensor kinase; Provisional

false

true

false

831

7e-09

57.39

14.08

5,375,554,43,418,603,8,426,612,13,439,627,38,477,667,4

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 376 VHLQADPDQLEQMMINLVKNAVEASKEMQQPETPEPPEVIVGW------DAEPAAII-LKVEDNGPGIMNP--SNAFVPF 446
PRK13837    555 AVVEGNPAQLQQVILNLCKNAAQAMDENGRVDIRLSRVDLRKPkvlahgTAPPGRYVlLRVSDTGRGIDEAvlPHIFEPF 634

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 94967406 447 YTTKQGGSGIGLVLSRQIAEAHGGRLELINR--EGTR 481
PRK13837    635 FTTRARGTGLGLATVHGIVSAHAGYIDVQSTvgRGTR 671

-1

138397

PRK11091

aerobic respiration control sensor protein ArcB; Provisional

false

true

false

779

4e-08

54.61

28.24

12,274,284,12,289,296,7,297,303,15,316,318,33,349,355,7,356,365,8,364,378,41,413,419,23,438,442,1,439,447,13,452,467,27,480,494,10

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 275 KLIRVLGHELNNslaPIKSIAGsLNSRLKRTSLSDEERedfeKGLSIVEGRAESLNRFLQAYRQLATMPPPKLKL----V 350
PRK11091    285 TFISTISHELRT---PLNGIVG-LSRMLLDTELTAEQE----KYLKTIHVSAITLGNIFNDIIDMDKMDRRKLQLdnqpV 356

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 351 SMKSLV---ERVAGLET-----RVVVEVRNNPDVHLQADPDQLEQMMINLVKNAVEASKEMQQpetpeppeVIVGWDAEP 422
PRK11091    357 DFTDFLadlENLSGLQAeqkglRFDLEPLLPLPHKVITDGTRLRQILWNLISNAVKFTQQGQV--------TVRVRYEDG 428

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 94967406 423 AAIILKVEDNGPGImnP----SNAFVPFYTTKQG-------GSGIGLVLSRQIAEAHGGRLELINREGtRGCMARVTLP 490
PRK11091    429 DMLHFEVEDSGIGI--PedelDKIFAMYYQVKDShggkpatGTGIGLAVSRRLAQNMGGDITVTSEEG-KGSTFTLTIH 504

-1

33099

COG3290

CitA

Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]

Signal transduction histidine kinase regulating citrate/malate metabolism [Signal...

false

true

false

537

2e-07

52.15

57.54

18,159,211,17,180,228,20,200,250,21,221,272,11,232,286,7,239,294,18,257,315,20,277,337,18,296,355,32,336,387,6,351,393,12,367,405,15,382,423,8,390,433,10,405,443,31,438,474,3,441,481,9,450,491,29

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 160 TSAIEATALLSRIVEEIdaplFAFDPEHKLKLVNSAGERLL--QQPATKLLGSTATELNLQVAF-EAESESLVPLP---Y 233
COG3290     212 TLLEERQAMLQSIKEGV----IAVDKKGVITLINQAAQKLLglRQPSGDPIGRSIVEVLPPDSDlPEVLETGKPQHdeeI 287

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 234 SPNSRW-MVRRSSFRQDGVPHTLIV---LSDVSRALREEERSAWQKLI--RVLGHELNNSLAPIKSIAgSLNSRLKRTSL 307
COG3290     288 RINGRLlVANRVPIRSGGQIVGAIItfrDKTEIKKLTEQLTGVRQYAEalRAQSHEFMNKLHTILGLL-QLGEYDDALDY 366

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 308 SDEEREDFEKGLSIVEGRAESlnrflqayRQLATMpppklklvsMKSLVERVAGLEtrvvVEVRNNPDVHLQADP---DQ 384
COG3290     367 IQQESEEQQELIDSLSEKIKD--------PVLAGF---------LLGKISRARELG----VSLIIDPNSQLPQLPselQP 425

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 385 LEQMMI--NLVKNAVEASkemqqPETPEPPEVIVGWDAEPAAIILKVEDNGPGImnPSN----AFVPFYTTK-QGGSGIG 457
COG3290     426 HDLVTIlgNLIDNALEAL-----LAPEENKEIELSLSDRGDELVIEVADTGPGI--PPEvrdkIFEKGVSTKnTGGRGIG 498

                       330       340
                ....*....|....*....|..
gi 94967406 458 LVLSRQIAEAHGGRLELINREG 479
COG3290     499 LYLVKQLVERLGGSIEVESEKG 520

-1

131984

TIGR02938

nifL_nitrog

nitrogen fixation negative regulator NifL

false

true

false

494

6e-07

50.67

73.89

17,165,128,34,199,167,16,215,191,20,236,211,9,245,232,38,283,275,5,288,281,11,299,301,44,349,345,16,365,367,11,376,379,35,414,414,4,419,418,17,438,435,3,441,442,11,452,456,21,474,477,16

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 166 TALLSRIVEEIDAPLFAFDPEHKLKLVNSAGERL-----LQQPATKLLGSTATEL--------NLQVAFEAESESLVPLP 232
TIGR02938   129 KLLIESVVDAAPVAFVLLDPTGRVILDNQEYKKLatdlrVKEPAHTVLDLLREAWrealaenwPQQLAFSNREARFDRGG 208

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 233 YSPnSRWMVRRSS------------FRQDGVPHTLIVLSDVSRALREEERSAWQKLIRVLGHE-----LNNSL-APIKSI 294
TIGR02938   209 GRP-ARWLSCTGSvigmesdcadsfFCAAEQPYLLLTIADISNLREEQERARLSALQALMAEEerleaIRETLsAAIHRL 287

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 295 AGSLN---------SRLKRTSLSDEEREDFEKGLSIVEGRAESLNRFLQAYRQLATMPppklklVSMKSLVERVAGLETR 365
TIGR02938   288 QGPMNlisaaisvlQRRGDDAGNPASAAMLQQALSAGREHMEALRQVIPQSPQEIVVP------VNLNQILRDVITLSTP 361

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 366 ------VVVEVRNNPDV-HLQADPDQLEQMMINLVKNAVEASKEMQQPETPEPpevIVGWdAEPAAIILKVEDNGPGImn 438
TIGR02938   362 rllaagIVVDWQPAATLpAILGRELQLRSLFKALVDNAIEAMNIKGWKRRELS---ITTA-LNGDLIVVSILDSGPGI-- 435

                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 94967406 439 PSN----AFVPFYTTKQG---GSGIGLVLSRQIAEAHGGRLElINREGTRGCMARVTLP 490
TIGR02938   436 PQDlrykVFEPFFTTKGGsrkHIGMGLSVAQEIVADHGGIID-LDDDYSEGCRIIVEFR 493

-1

138589

PRK11466

hybrid sensory histidine kinase TorS; Provisional

false

true

false

912

3e-06

48.48

15.46

5,343,520,61,413,581,23,436,606,11,447,619,37,485,656,5

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 344 PPKLKLVSMKSLVERVAGLETRVVVEVRNNPDVHLQADPDQLEQMMINLVKNAVEASKEMQqpetpeppeVIVGWDAEPA 423
PRK11466    521 PRPLLESTLQLMSGRVKGRPIRLATDIADDVPSALMGDPRRIRQVITNLLSNALRFTDEGS---------IVLRSRTDGE 591

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 94967406 424 AIILKVEDNGPGI--MNPSNAFVPFY--TTKQGGSGIGLVLSRQIAEAHGGRLELINREGTRGCMaRVTLP 490
PRK11466    592 QWLVEVEDSGCGIdpAKLAEIFQPFVqvSGKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCF-CLRLP 661

-1

137309

PRK09467

envZ

osmolarity sensor protein; Provisional

false

true

false

437

6e-06

47.60

15.79

6,426,365,16,442,383,4,449,387,3,452,397,25,477,423,2,481,425,9

                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 94967406 427 LKVEDNGPGIMNPSNA--FVPFyttKQG-------GSGIGLVLSRQIAEAHGGRLELINR-EGtrGCMARVTLP 490
PRK09467    366 FQVEDNGPGIPEEQIKhlFQPF---TRGdsargssGTGLGLAIVKRIVDQHQGKVELGNReEG--GLSARAWLP 434

-1

33927

COG4192

Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]

Signal transduction histidine kinase regulating phosphoglycerate transport system [...

false

true

false

673

6e-06

47.38

28.68

8,279,457,7,289,464,11,302,475,47,349,524,13,362,542,44,413,586,7,420,594,19,439,615,35

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 280 LGHELNNslaPIKSIAGSLNSrlKRTSLSDEEREDFEKGLSIVEGRAESLNRFLQAYRQLATMPPPKLKL--VSMKSLVE 357
COG4192     458 LAHEINQ---PLNAMSAYLFS--ARLALEEAPSAQAATSLDKIENLTERMGKIVNSLRQFARKNSSDESLqpVRLNSVVE 532

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 358 RVAGL-----ETRVVVEVRNNPDVHLQADPDQLEQMMINLVKNAVEASKEMQQPetpeppeVIVGWDA-EPAAIILKVED 431
COG4192     533 QAWELlqtkhKRRQIKLINPTDDLMVMGDAVSIEQVLVNLIVNALDASTHFAPW-------IKLIALGtEQEMLRIAIID 605

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 94967406 432 NGPGIMNP--SNAFVPFYTTKQGGSGIGLVLSRQIAEAHGGRLEL 474
COG4192     606 NGQGWPHElvDKLLTPFTTSKEVGLGLGLSISQSLMEQMQGRLAL 650

-1

138336

PRK11006

phoR

phosphate regulon sensor protein; Provisional

false

true

false

431

1e-05

46.24

24.83

5,372,305,26,406,331,30,439,361,6,445,372,2,447,380,32

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 373 NPDVHLQADPDQLEQMMINLVKNAVEaskemqqpETPEPPEVIVGWDAEPAAIILKVEDNGPGImnpSNAFVP-----FY 447
PRK11006    306 DDSLKVLGNEDQLRSAISNLVYNAVN--------HTPEGTHITVRWQRVPHGAEFSVEDNGPGI---APEHIPrlterFY 374

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 94967406 448 ------TTKQGGSGIGLVLSRQIAEAHGGRLELINREG 479
PRK11006    375 rvdkarSRQTGGSGLGLAIVKHALNHHDSRLEIESTVG 412

-1

132001

TIGR02956

TMAO_torS

TMAO reductase sytem sensor TorS

false

true

false

968

5e-05

44.38

11.36

6,377,572,20,400,592,17,422,609,20,442,631,7,449,642,30,480,672,10

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 378 LQADPDQLEQMMINLVKNAVeasKEMQQPETPEPPEVIVGwdaepAAIILKVEDNGPGIMNPSNA--FVPFYTT----KQ 451
TIGR02956   573 WQGDGPRIRQVLINLVGNAI---KFTDRGSVVLRVSLNDD-----SSLLFEVEDTGCGIAEEEQAtlFDAFTQAdgrrRS 644

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 94967406 452 GGSGIGLVLSRQIAEAHGGRLELINREGtRGCMARVTLP 490
TIGR02956   645 GGTGLGLAISQRLVEAMDGELGVESELG-VGSCFWFTLP 682

-1

137977

PRK10549

signal transduction histidine-protein kinase BaeS; Provisional

false

true

false

467

2e-04

42.40

19.91

4,379,348,18,405,366,34,439,402,11,450,419,22

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 380 ADPDQLEQMMINLVKNAVeaskemqqPETPEPPEVIVGWDAEPAAIILKVEDNGPGIMNP--SNAFVPFYTTK------Q 451
PRK10549    349 GDPDRLMQLFNNLLENSL--------RYTDSGGSLHISAEQHDKTLRLTFADSAPGVSDEqlQKLFERFYRTEgsrnraS 420

                        90       100
                ....*....|....*....|.
gi 94967406 452 GGSGIGLVLSRQIAEAHGGRL 472
PRK10549    421 GGSGLGLAICLNIVEAHNGRI 441

-1

138021

PRK10604

sensor protein RstB; Provisional

false

true

false

433

3e-04

41.60

44.11

10,273,212,16,300,228,3,303,232,36,340,268,11,355,279,24,379,314,21,410,335,26,437,361,5,442,369,6,448,381,22

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 274 QKLIRVLGHELNNSLApiksiagslnsRLK-RTSLSDEEREDFEKGLSIVEGRAESLNRFLQAYRQLaTMPPPKLKLVSm 352
PRK10604    213 KQLIDGIAHELRTPLV-----------RLRyRLEMSDNLSAAESQALNRDIGQLEALIEELLTYARL-DRPQNELHLSE- 279

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 353 kslVERVAGLETRVVVEVRNNPDVHLQ-----------ADPDQLEQMMINLVKNAVEASkemqqpetpePPEVIVGWDAE 421
PRK10604    280 ---PDLPAWLSTHLADIQAVTPEKTVRlktphqgdygaLDMRLMERVLDNLLNNALRYS----------HSTVETSLLLD 346

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 94967406 422 PAAIILKVEDNGPGImNPSNA---FVPFYT------TKQGGSGIGLVLSRQIAEAHGG 470
PRK10604    347 GDQATLIVEDDGPGI-APEEReriFEPFVRldpsrdRATGGCGLGLAIVHSIALAMGG 403

-1

137202

PRK09303

adaptive-response sensory kinase; Validated

false

true

false

378

4e-04

41.48

61.38

15,254,124,14,268,143,6,274,150,16,291,166,4,295,171,9,305,180,27,332,211,9,341,223,11,352,243,18,373,261,4,379,265,18,397,287,19,427,306,9,436,317,16,452,337,19

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 255 LIVLSDVSRALREE-----ERSAWQ-KLIRVLGHELNNSLAPiKSIA-GSLNSRLKRtSLSDEEREDFEKGLSIVEGRAE 327
PRK09303    125 LLQLSDELFVLRQEnetllEQLKFKdRLLAMLAHDLRTPLTA-ASLAvETLELGQID-PSEELSPALIEQLQDQARRQLE 202

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 328 SLNRF----LQAYRQLAT---MPPPKLKLVSM---------KSLVERVAGLETRVVVEVrnnPDVHlqADPDQLEQMMIN 391
PRK09303    203 EIERLitdlLEVGRTRWEalqFNPQKLDLGSLcqevileleKRWLAKSLEIQTDIPSDL---PSVY--ADQRRIRQVLLN 277

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 392 LVKNAV----EASKEMQQPETPEPPEVIVgwdaepaaiilKVEDNGPGI--MNPSNAFVPFYTTKQG----GSGIGLVLS 461
PRK09303    278 LLDNAIkytpEGGTITLTMLHRTTQKVQV-----------SICDTGPGIpeEEQERIFEDRVRLPRDegteGYGIGLSVC 346

                       250
                ....*....|
gi 94967406 462 RQIAEAHGGR 471
PRK09303    347 RRIVEVHYGQ 356

-1

139663

PRK13557

histidine kinase; Provisional

false

true

false

538

8e-04

40.48

41.08

12,259,140,4,263,150,7,270,158,37,308,195,7,315,204,8,324,212,14,345,226,5,350,242,13,365,255,11,376,267,48,424,322,20,444,344,17

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 260 DVSR------ALREEER-SAWQKLIRVLGHELNNSLAPIKSIAGSLNSRLKRTSLsDEEREDF--EKGLSIVEgRAESLN 330
PRK13557    141 DVSRrrdaedALRQAQKmEALGQLTGGIAHDFNNLLQVMSGYLDVLQMALSKPDA-DRERIARsvEHIRAAAE-RAATLT 218

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 331 RFLQAYRQlatmpppKLKLV-----------SMKSLVERVAGLEtrVVVEVRNNPDV-HLQADPDQLEQMMINLVKNAVE 398
PRK13557    219 QQLLAFAR-------KQKLDgrvvnlnglvsGMGEMAERTLGDA--VTIETDLAPDLwNCRIDPTQAEVALLNVLINARD 289

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 94967406 399 ASKEMQQPETPEPPEVIVGWDAEPAA-------IILKVEDNGPGIMNPSNAFV--PFYTTKQGGSGIGLVLS 461
PRK13557    290 AMPEGGRVTVRTENVEITEHDLAMYHqlppgryVSIAVTDTGSGMPPEILARVmePFFTTKEEGKGTGLGLS 361

-1

130453

TIGR01386

cztS_silS_copS

heavy metal sensor kinase

false

true

false

457

0.001

40.06

23.85

6,362,333,15,379,348,21,406,369,15,423,384,16,439,402,8,447,416,26

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 363 ETRVVVEVRNNPDVHlqADPDQLEQMMINLVKNAVEASkemqqpETPEPPEVIVGWDAEpaAIILKVEDNGPGIMNP--S 440
TIGR01386   334 ERGVRIRVEGEGLVR--GDPQMFRRAISNLLSNALRHT------PDGGTITVRIERRSD--EVRVSVSNPGPGIPPEhlS 403

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 94967406 441 NAFVPFY------TTKQGGSGIGLVLSRQIAEAHGGRLE 473
TIGR01386   404 RLFDRFYrvdparSNSGEGTGLGLAIVRSIMEAHGGRAS 442

-1

137934

PRK10490

sensor protein KdpD; Provisional

false

true

false

895

0.001

40.11

11.51

5,384,778,14,406,792,38,445,830,7,452,844,32,485,876,5

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 385 LEQMMINLVKNAVEaskemqqpETPEPPEVIVGWDAEPAAIILKVEDNGPGIMNPSNAFVpFYTTKQG-------GSGIG 457
PRK10490    779 FERVLINLLENAVK--------YAGAQAEIGIDAHVEGENLQLDVWDNGPGIPPGQEQLI-FDKFARGnkesavpGVGLG 849

                        90       100       110
                ....*....|....*....|....*....|...
gi 94967406 458 LVLSRQIAEAHGGRLELINREGTRGCMaRVTLP 490
PRK10490    850 LAICRAIVDVHGGTITAENRPEGGACF-RVTLP 881

-1

138393

PRK11086

sensory histidine kinase DcuS; Provisional

false

true

false

541

0.001

39.93

15.71

3,390,438,28,424,466,12,436,480,43

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 391 NLVKNAVEASKEMQQPETPEPPEVIVGWdaepaaIILKVEDNGPGI--MNPSNAFVPFYTTKQGGSGIGLVLSRQIAEAH 468
PRK11086    439 NLIENALEAVSNEEGGEISVSLHYRHGW------LHIEVSDDGPGIapEEIEAIFDKGYSTKGSNRGVGLYLVKQSVENL 512

                        90
                ....*....|.
gi 94967406 469 GGRLELINREG 479
PRK11086    513 GGSIAVESEPG 523

-1

137828

PRK10337

sensor protein QseC; Provisional

false

true

false

446

0.004

38.22

24.44

5,359,327,9,371,336,35,418,371,26,444,399,4,448,406,30

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967406 360 AGLETRVVVevrNNPDVHLQADPDQLEQMMINLVKNAVEASKEMQQPetpeppevivgwDAEPAAIILKVEDNGPGIMNP 439
PRK10337    328 AKIDVRLTL---NAHGIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVV------------DVTLNARNFTVRDNGPGVTPE 392

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 94967406 440 SNAFV--PFYT---TKQGGSGIGLVLSRQIAEAHGGRLELINRE 478
PRK10337    393 ALARIgeRFYRppgQTATGSGLGLSIVQRIAKLHGMNVSFGNAE 436

-1

ATP binding site	0	17	17	true	28956	cd00075	HATPase_c
Mg2+ binding site	1	1	1	true	28956	cd00075	HATPase_c
G-X-G motif	2	4	4	true	28956	cd00075	HATPase_c