NCBI Conserved Domain Search

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Conserved domains on [gi\|94967235\|ref\|YP_589283.1\|]
diguanylate cyclase [Candidatus Koribacter versatilis Ellin345]

Graphical summary show options »	Show site features Horizontal zoom: ×	?



List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

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of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

133472

cd01949

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as domain of unknown function 1 (DUF1). It is widely present in bacteria and often links to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain has been suggested to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesiveness in bacteria.

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

true

false

true

157

3e-47

184.71

99.36

5,281,0,70,352,70,45,400,115,11,415,126,8,427,134,22

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 282 RDGLTGLYNRRFFDTTLTAECKRAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVRRtSDVVARYGG 361
cd01949       1 TDPLTGLPNRRAFEERLERLLARARRSGRPLALLLIDLDHFKQINDTYGHAAGDEVLKEVARRLRSSLRE-SDLVARLGG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 362 EEFALILPNTSEESATTIGENIRRAVLGLEIANANStagPFVTLSVGVCTrrpsHPRSSEDIlvttNEIIRAADEALYRA 441
cd01949      80 DEFAILLPGTDLEEAEELAERLRKAIEEPFFIDGEE---IRVTASIGIAE----YPEDGEDL----EELLRRADKALYQA 148


                ....*...
gi 94967235 442 KREGRNRV 449
cd01949     149 KRSGRNRV 156

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

110022

pfam00990

GGDEF

GGDEF domain

false

160

2e-49

191.69

100.00

3,279,0,72,352,72,65,425,137,23

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 280 STRDGLTGLYNRRFFDTTLTAECKRAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVRRtSDVVARY 359
pfam00990     1 AAHDPLTGLPNRRYFEEELEQELQRAQRRQSPLALLLLDLDNFKRINDTYGHAVGDEVLQEVAQRLSSSLRR-SDLVARL 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 360 GGEEFALILPNTSEESATTIGENIRRAVLGLEIANANSTAGPFVTLSVGVCTRRPSHPrssedilvTTNEIIRAADEALY 439
pfam00990    80 GGDEFAILLPDTSLEGAQELAERIRRLLAALKIPHTLSGLPLYVTISIGIAAYPNDGE--------DAEDLLKRADQALY 151


                ....*....
gi 94967235 440 RAKREGRNR 448
pfam00990   152 QAKNQGRNR 160

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

129356

TIGR00254

GGDEF

diguanylate cyclase (GGDEF) domain

false

165

4e-46

181.00

96.97

5,279,1,70,350,71,50,401,121,13,415,134,6,428,140,21

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 280 STRDGLTGLYNRRFFDTTLTAECKRAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVrRTSDVVARY 359
TIGR00254     2 AVRDPLTGLYNRRYLEEMLDSELKRARRFQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSV-RGSDVVGRY 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 360 GGEEFALILPNTSEESATTIGENIRRAVLGLEIANANSTAGpFVTLSVGVCTRRPsHPRSSEdilvttnEIIRAADEALY 439
TIGR00254    81 GGEEFVVILPGTPLEDALSKAERLRDAINSKPIEVAGSETL-TVTVSIGVACYPG-HGLTLE-------ELLKRADEALY 151

                       170
                ....*....|
gi 94967235 440 RAKREGRNRV 449
TIGR00254   152 QAKKAGRNRV 161

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

128563

smart00267

GGDEF

diguanylate cyclase

false

163

1e-44

176.28

96.93

4,279,2,72,352,74,45,400,119,17,425,136,24

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 280 STRDGLTGLYNRRFFDTTLTAECKRAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVRRtSDVVARY 359
smart00267    3 AFRDPLTGLPNRRYFEEELEQELQRAQRQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRP-GDLLARL 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 360 GGEEFALILPNTSEESATTIGENIRRAVLGLEIANANStagPFVTLSVGVCTRRPSHPrssedilvTTNEIIRAADEALY 439
smart00267   82 GGDEFALLLPETSLEEAIALAERILQQLREPIIIHGIP---LYLTISIGVAAYPNPGE--------DAEDLLKRADTALY 150

                       170
                ....*....|
gi 94967235 440 RAKREGRNRV 449
smart00267  151 QAKKAGRNQV 160

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

32381

COG2199

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction...

false

181

3e-37

151.43

87.85

4,279,19,72,352,91,35,390,126,31,428,157,21

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 280 STRDGLTGLYNRRFFDTTLTAECKRAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVRRtSDVVARY 359
COG2199      20 ALHDPLTGLPNRRAFEERLERALARARRHGEPLALLLLDLDHFKQINDTYGHAAGDEVLREVARRLRSNLRE-GDLVARL 98

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 360 GGEEFALILPNTSEESATTIGENIRRAVlglEIANANSTAGPFVTLSVGVCTRRPSHPRSSEdilvttnEIIRAADEALY 439
COG2199      99 GGDEFAVLLPGTSLEEAARLAERIRAAL---EEPFFLGGEELRVTVSIGVALYPEDGSDDAE-------LLLRRADLALY 168

                       170
                ....*....|
gi 94967235 440 RAKREGRNRV 449
COG2199     169 RAKRAGRNRV 178

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

112517

pfam03707

MHYT

Bacterial signalling protein N terminal repeat

true

false

3e-05

45.08

80.65

1,116,0,50

                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 94967235 117 GGGIGAMHYTGMAAMRSYAMHRYNPSLVLLSLVIAVAFSWMALRITFLLR 166
pfam03707     1 GLGIWAMHYTGMAAFHLPGPIEYDPLLVLLSLLIAVAASAVALWLAFRAR 50

pfam03707

112517

MHYT

Bacterial signalling protein N terminal repeat

-1

112517

pfam03707

MHYT

Bacterial signalling protein N terminal repeat

true

false

4e-04

41.23

48.39

1,53,0,30

                        10        20        30
                ....*....|....*....|....*....|
gi 94967235  54 GLGIWSMHYLGMLAVQLPVPVVYHVPTVII 83
pfam03707     1 GLGIWAMHYTGMAAFHLPGPIEYDPLLVLL 30

pfam03707

112517

MHYT

Bacterial signalling protein N terminal repeat

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

3e-41

164.71

37.24

3,282,272,70,353,342,64,425,406,28

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 283 DGLTGLYNRRFFDTTLTAECKRAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVRRTsDVVARYGGE 362
COG3706     273 DGLTGLFNRRYFDEHLADLWKRALREGRPLSLLMLDIDDFKEINDTYGHDVGDEVLRQVARRLRQTVRGL-DLVARYGGE 351

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 363 EFALILPNTSEESATTIGENIRRAVLGLEIANANSTAGPFVTLSVGVCTRRPSHPrssedilvTTNEIIRAADEALYRAK 442
COG3706     352 EFAVVLPDTDLEAAIAIAERIRQKINELPFVHELSREPLEVTISIGVAEGKPGED--------SIEELLKRADKALYKAK 423

                       170
                ....*....|.
gi 94967235 443 REGRNRVLLGA 453
COG3706     424 ASGRNRVVVKR 434

-1

137400

PRK09581

pleD

response regulator PleD; Reviewed

false

true

false

457

3e-40

161.62

36.11

3,279,291,73,353,364,64,425,428,28

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 280 STRDGLTGLYNRRFFDTTLTAECKRAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVRRTsDVVARY 359
PRK09581    292 AVTDGLTGLHNRRYFDMHLKQLIERANERGKPLSLMMLDIDHFKQVNDTYGHDAGDEVLREFAKRLRKNIRGT-DLIARY 370

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 360 GGEEFALILPNTSEESATTIGENIRRAVLGLEIANANSTAGPFVTLSVGVCTRRPSHPrssedilvTTNEIIRAADEALY 439
PRK09581    371 GGEEFVVVMPDTDIEVAIAVAERIRRKIAEEPFAISDGKERLNVTVSIGVAELRPSGE--------SIEALIKRADKALY 442

                       170
                ....*....|....
gi 94967235 440 RAKREGRNRVLLGA 453
PRK09581    443 EAKNTGRNRVVALA 456

-1

137576

PRK09894

hypothetical protein; Provisional

false

true

false

293

3e-29

124.82

53.92

5,279,129,19,300,148,51,352,199,48,402,247,13,424,260,27

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 280 STRDGLTGLYNRRFFDTTLtaECKRAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVRRtSDVVARY 359
PRK09894    130 SNMDVLTGLPGRRVLDESF--DHQLRNREPLNLYLALLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRP-YETVYRY 206

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 360 GGEEFALILPNTSEESATTIGENIRRAVLGLEIANANSTAGpfVTLSVGVCTRRPShprssedilVTTNEIIRAADEALY 439
PRK09894    207 GGEEFIIILKAATDEEACRAGERIRQLIANQAITHSEGRIN--ITATFGVTRAFPE---------EPLDEVIGRADRAMY 275

                       170
                ....*....|..
gi 94967235 440 RAKREGRNRVLL 451
PRK09894    276 EGKQAGRNRVMF 287

-1

33109

COG3300

MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]

true

false

236

1e-28

123.04

87.29

4,31,30,46,78,76,93,172,169,46,219,215,21

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235  32 ERVAASDRQRSLGWLIAGAFAMGLGIWSMHYLGMLAVQLPVPVVYHvPTVIISLLLAVAASAAVLWVVSRESLSGRAIVL 111
COG3300      31 SRARGATGRQSRIWLLLGAFAMGLGIWATHFVAMLAFHPGIPIGYD-PFLTGLSLLIAVAGSAAALWVSAARLRLYRLLV 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 112 GSVAMGGGIGAMHYTGMAAMRSYAMHRYNPSLVLLSLVIAVAFSWMALRITFLLRREPGAhELRRMGGAVLMGIGIASMH 191
COG3300     110 GGLLLGLGIAAMHYTGMAAMEVQGTIVYDPALVALSVLIAVAASFVALWLFFRLRGSRRS-RLRRAVAALLLGLAIVGMH 188

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 94967235 192 YTAMFAVTFERGNTEFSTVHTVPVTHIdQLGIVVMAGMVLFGALISAYF 240
COG3300     189 FTGMAAAVFPPDPSIPGPHQGVDPLWL-AGAVIVVTLLILALGLLASLI 236

-1

137770

PRK10245

adrA

diguanylate cyclase AdrA; Provisional

false

true

false

371

1e-25

113.07

43.67

6,279,209,70,350,279,45,400,324,5,405,331,9,414,342,4,428,346,25

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 280 STRDGLTGLYNRRFFDTTLTAECKRAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVrRTSDVVARY 359
PRK10245    210 STRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQITL-RGSDVIGRF 288

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 360 GGEEFALILPNTSEESATTIGENIRRAVLGLEIANAnstagPFVTL--SVGVCTRRP--SHPRssedilvttnEIIRAAD 435
PRK10245    289 GGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNA-----PQVTLriSVGVAPLNPqmSHYR----------EWLKSAD 353

                       170
                ....*....|....*...
gi 94967235 436 EALYRAKREGRNRVLLGA 453
PRK10245    354 LALYKAKKAGRNRTEVAA 371

-1

34606

COG5001

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF...

false

true

false

663

4e-19

90.85

28.36

5,252,200,93,346,293,54,402,347,9,412,356,12,431,368,20

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 253 ERLAEMQVALLQREKELKEAVAKLEELSTRDGLTGLYNRRFFDTTLTAECKRAARANYPISLLIIDVDCFKALNDHYGHL 332
COG5001     201 SDMVQSQVTLTQRAEETRRLSDENDRLANLDSLTGLPNRRRFFAELDARLAAARQSGRRLVLGVIDLDGFKPVNDAFGHA 280

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 333 VGDDCLQKVGKSLaSAVRRTSDVVARYGGEEFALILPNTSEESATTIGENIRRAVLGLEIANANSTAGpfVTLSVGVCTr 412
COG5001     281 TGDRLLIEVGRRL-KAFDGAPILAARLGGDEFALIIPALEDDALRVAGARALCESLQAPYDLRGVRVQ--VGASIGIAP- 356

                       170       180       190
                ....*....|....*....|....*....|....*....
gi 94967235 413 RPSHPRSSEDILvttneiiRAADEALYRAKREGRNRVLL 451
COG5001     357 FPSGADTSEQLF-------ERADYALYHAKQNGKGAAVL 388

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

7e-19

90.15

14.25

5,279,687,71,351,758,32,391,790,11,402,807,18,428,825,21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235  280 STRDGLTGLYNRRFFDTTLTAECKRAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVRrTSDVVARY 359
PRK09776     688 ASHDALTGLANRASFEKQLREALQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALLRELASLMLSMLR-SSDVLARL 766

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235  360 GGEEFALILPNTSEESATTIGENIrravlgleIANANSTAGPF------VTLSVGVCTRRPSHPRSSedilvttnEIIRA 433
PRK09776     767 GGDEFGLLLPDCNVESARFIATRI--------ISAINDYRFPWegrvyrVGASAGITAIDDNNHQAS--------EVMSQ 830

                        170
                 ....*....|....*.
gi 94967235  434 ADEALYRAKREGRNRV 449
PRK09776     831 ADIACYAAKNAGRGRV 846

-1

137662

PRK10060

RNase II stability modulator; Provisional

false

true

false

663

6e-16

80.54

22.62

9,282,239,20,304,259,45,350,304,22,372,330,15,387,346,3,390,350,2,401,352,8,410,360,11,428,371,18

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 283 DGLTGLYNRRFFDTTLTAECkrAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVrRTSDVVARYGGE 362
PRK10060    240 DSITGLPNRNAIQELIDHAI--AQADNNQVGIVYLDLDNFKKVNDAYGHMFGDQLLQDVSLAILSCL-EEDQTLARLGGD 316

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 363 EFALILPNTS----EESATTIGENIRRAV-LGL-EIananstagpFVTLSVGVcTRRPSHPRSSEdilvttnEIIRAADE 436
PRK10060    317 EFLVLASHTSqaalEAMASRILTRLRLPFrIGLiEV---------YTGCSIGI-ALSPEHGDDSE-------SLIRSADT 379

                       170
                ....*....|
gi 94967235 437 ALYRAKREGR 446
PRK10060    380 AMYTAKEGGR 389

-1

138376

PRK11059

regulatory protein CsrD; Provisional

false

true

false

642

4e-09

57.97

16.98

2,282,230,74,356,305,34

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 283 DGLTGLYNRRFFDTTLTAECKRAARANYPISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVRRTSDVV-ARYGG 361
PRK11059    231 DAKTGLGNRLFFDNQLDTLLEDQEKVGAHGVVMLIRLPDFDLLQEELGESQVDELLFELINLLSTFVQRYPGALlARYSR 310

                        90       100
                ....*....|....*....|....*....
gi 94967235 362 EEFALILPNTSEESATTIGENIRRAVLGL 390
PRK11059    311 SDFAVLLPHRSLKEADSLASQLLKAVDSL 339

-1

137615

PRK09966

hypothetical protein; Provisional

false

true

false

407

9e-09

56.57

34.64

7,240,200,6,248,206,12,260,224,22,282,250,24,307,274,40,347,316,6,356,322,19

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 241 DRQMSRdlRVSNERLAEMQV------ALLQREKELKEAVAKLEELSTR----DGLTGLYNRRFFDTTLTAECKRAArANY 310
PRK09966    201 NRNFSR--RVSEERIAEFHRfaldfnSLLDEMEEWQLRLQAKNAQLLRtalhDPLTGLANRAAFRSGINTLMNNSD-ARK 277

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 94967235 311 PISLLIIDVDCFKALNDHYGHLVGDDCLQKVGKSLAS--AVRRTSdvvARYGGEEFALILPNTSEES 375
PRK09966    278 TSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEfgGLRHKA---YRLGGDEFAMVLYDVQSES 341

-1

138538

PRK11359

cAMP phosphodiesterase; Provisional

false

true

false

799

9e-05

43.29

18.40

7,282,378,17,302,395,14,317,409,32,350,441,35,386,476,15,403,491,6,419,497,28

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 283 DGLTGLYNRRFFDTTLTaecKRAARANYPISLLIiDVDCFKALNDHYGHLVGDDCLQKVGKSLASAVrRTSDVVARYGGE 362
PRK11359    379 DPMTGLPNRNNLHNYLD---DLVDKAVSPVVYLI-GVDHIQDVIDSLGYAWADQALLEVVNRFREKL-KPDQYLCRIEGT 453

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94967235 363 EFALILPNTSEESATTIGENIRRaVLGLEIANANSTAGPfvTLSVGVctrrpshprsSEDILVTTNEIIRAADEALYRAK 442
PRK11359    454 QFVLVSLENDVSNITQIADELRN-VVSKPIMIDDKPFPL--TLSIGI----------SYDVGKNRDYLLSTAHNAMDYIR 520


                ....*
gi 94967235 443 REGRN 447
PRK11359    521 KNGGN 525

-1

active site	0	10	10	true	133472	cd01949	GGDEF
I-site	1	3	3	true	133472	cd01949	GGDEF