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Conserved domains on  [gi|6680047|ref|NP_032169|]
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guanine nucleotide-binding protein subunit beta-2-like 1 [Mus musculus]

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List of domain hits

Name Accession Description Interval E-value
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
7-311 5.43e-94

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


:

Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 283.07  E-value: 5.43e-94
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    7 LRGTLKGHNGWVTQIATTPQfPDMILSASRDKTIIMWKLTRDEtnygiPQRALRGHSHFVSDVVISSDGQFALSGSWDGT 86
Cdd:cd00200   1 LRRTLKGHTGGVTCVAFSPD-GKLLATGSGDGTIKVWDLETGE-----LLRTLKGHTGPVRDVAASADGTYLASGSSDKT 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDesHSEWVSCVRFSPNssNPII 165
Cdd:cd00200  75 IRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVEtGKCLTTLRG--HTDWVNSVAFSPD--GTFV 150
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047  166 VSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALCFSPN 244
Cdd:cd00200 151 ASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGhENGVNSVAFSPD 230
                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6680047  245 RYWLCAATG-PSIKIWDLEGKIIVDELkqevistssKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQ 311
Cdd:cd00200 231 GYLLASGSEdGTIRVWDLRTGECVQTL---------SGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
COG2319 COG2319
FOG: WD40 repeat [General function prediction only]
2-310 5.72e-41

FOG: WD40 repeat [General function prediction only]


:

Pssm-ID: 225201 [Multi-domain]  Cd Length: 466  Bit Score: 149.08  E-value: 5.72e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDEtnygiPQRALRGHSHFVSDVVISSDGQF-ALS 80
Cdd:COG2319 142 STPGKLIRTLEGHSESVTSLAFSPDGKLLASGSSLDGTIKLWDLRTGK-----PLSTLAGHTDPVSSLAFSPDGGLlIAS 216
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   81 GSWDGTLRLWDLTTGTTTR-RFVGHTKDVLSvAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPN 159
Cdd:COG2319 217 GSSDGTIRLWDLSTGKLLRsTLSGHSDSVVS-SFSPDGSLLASGSSDGTIRLWDLRSSSSLLRTLSGHSSSVLSVAFSPD 295
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047  160 SSnpIIVSCGWDKLVKVWNLAN--CKLKTNHIGHTGYLNTVTVSPDGSLCASGG-KDGQAMLWDLNEGKHLYTLDGGDII 236
Cdd:COG2319 296 GK--LLASGSSDGTVRLWDLETgkLLSSLTLKGHEGPVSSLSFSPDGSLLVSGGsDDGTIRLWDLRTGKPLKTLEGHSNV 373
                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6680047  237 NALCFSPNRYWLC-AATGPSIKIWDLEGKIIVDELKQEVISTsskaeppqcTSLAWSADGQTLFAGYTDNLVRVW 310
Cdd:COG2319 374 LSVSFSPDGRVVSsGSTDGTVRLWDLSTGSLLRNLDGHTSRV---------TSLDFSPDGKSLASGSSDNTIRLW 439
 
Name Accession Description Interval E-value
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
7-311 5.43e-94

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 283.07  E-value: 5.43e-94
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    7 LRGTLKGHNGWVTQIATTPQfPDMILSASRDKTIIMWKLTRDEtnygiPQRALRGHSHFVSDVVISSDGQFALSGSWDGT 86
Cdd:cd00200   1 LRRTLKGHTGGVTCVAFSPD-GKLLATGSGDGTIKVWDLETGE-----LLRTLKGHTGPVRDVAASADGTYLASGSSDKT 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDesHSEWVSCVRFSPNssNPII 165
Cdd:cd00200  75 IRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVEtGKCLTTLRG--HTDWVNSVAFSPD--GTFV 150
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047  166 VSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALCFSPN 244
Cdd:cd00200 151 ASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGhENGVNSVAFSPD 230
                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6680047  245 RYWLCAATG-PSIKIWDLEGKIIVDELkqevistssKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQ 311
Cdd:cd00200 231 GYLLASGSEdGTIRVWDLRTGECVQTL---------SGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 pfam00400
WD domain, G-beta repeat;
95-133 6.68e-09

WD domain, G-beta repeat;


Pssm-ID: 249832  Cd Length: 39  Bit Score: 50.82  E-value: 6.68e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 6680047     95 GTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133
Cdd:pfam00400   1 GKLLRTLKGHTGPVTSVAFSPDGNLLASGSDDGTVRVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
94-133 1.77e-08

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651  Cd Length: 40  Bit Score: 50.00  E-value: 1.77e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 6680047      94 TGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
COG2319 COG2319
FOG: WD40 repeat [General function prediction only]
2-310 5.72e-41

FOG: WD40 repeat [General function prediction only]


Pssm-ID: 225201 [Multi-domain]  Cd Length: 466  Bit Score: 149.08  E-value: 5.72e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDEtnygiPQRALRGHSHFVSDVVISSDGQF-ALS 80
Cdd:COG2319 142 STPGKLIRTLEGHSESVTSLAFSPDGKLLASGSSLDGTIKLWDLRTGK-----PLSTLAGHTDPVSSLAFSPDGGLlIAS 216
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   81 GSWDGTLRLWDLTTGTTTR-RFVGHTKDVLSvAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPN 159
Cdd:COG2319 217 GSSDGTIRLWDLSTGKLLRsTLSGHSDSVVS-SFSPDGSLLASGSSDGTIRLWDLRSSSSLLRTLSGHSSSVLSVAFSPD 295
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047  160 SSnpIIVSCGWDKLVKVWNLAN--CKLKTNHIGHTGYLNTVTVSPDGSLCASGG-KDGQAMLWDLNEGKHLYTLDGGDII 236
Cdd:COG2319 296 GK--LLASGSSDGTVRLWDLETgkLLSSLTLKGHEGPVSSLSFSPDGSLLVSGGsDDGTIRLWDLRTGKPLKTLEGHSNV 373
                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6680047  237 NALCFSPNRYWLC-AATGPSIKIWDLEGKIIVDELKQEVISTsskaeppqcTSLAWSADGQTLFAGYTDNLVRVW 310
Cdd:COG2319 374 LSVSFSPDGRVVSsGSTDGTVRLWDLSTGSLLRNLDGHTSRV---------TSLDFSPDGKSLASGSSDNTIRLW 439
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
80-222 1.11e-09

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 58.17  E-value: 1.11e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    80 SGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS-DNRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHsewVSCVRFs 157
Cdd:PLN00181 550 SSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSaDPTLLASGSDDGSVKLWSiNQGVSIGTIKTKAN---ICCVQF- 625
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6680047   158 PNSSNPIIVSCGWDKLVKVWNLANCKLK-TNHIGHTGYLNTVTVSpDGSLCASGGKDGQAMLWDLN 222
Cdd:PLN00181 626 PSESGRSLAFGSADHKVYYYDLRNPKLPlCTMIGHSKTVSYVRFV-DSSTLVSSSTDNTLKLWDLS 690
PTZ00421 PTZ00421
coronin; Provisional
102-213 9.68e-07

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 48.74  E-value: 9.68e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   102 VGHTKDVLSVAFSS-DNRQIVSGSRDKTIKLWN------TLGVCKYTVQDESHSEWVSCVRFSPnSSNPIIVSCGWDKLV 174
Cdd:PTZ00421  72 LGQEGPIIDVAFNPfDPQKLFTASEDGTIMGWGipeeglTQNISDPIVHLQGHTKKVGIVSFHP-SAMNVLASAGADMVV 150
                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 6680047   175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKD 213
Cdd:PTZ00421 151 NVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKD 189
 
Name Accession Description Interval E-value
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
7-311 5.43e-94

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 283.07  E-value: 5.43e-94
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    7 LRGTLKGHNGWVTQIATTPQfPDMILSASRDKTIIMWKLTRDEtnygiPQRALRGHSHFVSDVVISSDGQFALSGSWDGT 86
Cdd:cd00200   1 LRRTLKGHTGGVTCVAFSPD-GKLLATGSGDGTIKVWDLETGE-----LLRTLKGHTGPVRDVAASADGTYLASGSSDKT 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDesHSEWVSCVRFSPNssNPII 165
Cdd:cd00200  75 IRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVEtGKCLTTLRG--HTDWVNSVAFSPD--GTFV 150
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047  166 VSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALCFSPN 244
Cdd:cd00200 151 ASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGhENGVNSVAFSPD 230
                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6680047  245 RYWLCAATG-PSIKIWDLEGKIIVDELkqevistssKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQ 311
Cdd:cd00200 231 GYLLASGSEdGTIRVWDLRTGECVQTL---------SGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
2-133 3.51e-27

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 107.81  E-value: 3.51e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    2 TEQMTLRGTLKGHNGWVTQIATTPQfPDMILSASRDKTIIMWkltrdETNYGIPQRALRGHSHFVSDVVISSDGQFALSG 81
Cdd:cd00200 164 LRTGKCVATLTGHTGEVNSVAFSPD-GEKLLSSSSDGTIKLW-----DLSTGKCLGTLRGHENGVNSVAFSPDGYLLASG 237
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 6680047   82 SWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133
Cdd:cd00200 238 SEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 pfam00400
WD domain, G-beta repeat;
95-133 6.68e-09

WD domain, G-beta repeat;


Pssm-ID: 249832  Cd Length: 39  Bit Score: 50.82  E-value: 6.68e-09
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 6680047     95 GTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133
Cdd:pfam00400   1 GKLLRTLKGHTGPVTSVAFSPDGNLLASGSDDGTVRVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
94-133 1.77e-08

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651  Cd Length: 40  Bit Score: 50.00  E-value: 1.77e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 6680047      94 TGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 133
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
53-91 1.52e-07

WD domain, G-beta repeat;


Pssm-ID: 249832  Cd Length: 39  Bit Score: 47.35  E-value: 1.52e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 6680047     53 GIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWD 91
Cdd:pfam00400   1 GKLLRTLKGHTGPVTSVAFSPDGNLLASGSDDGTVRVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
53-91 5.84e-07

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651  Cd Length: 40  Bit Score: 45.38  E-value: 5.84e-07
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 6680047      53 GIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWD 91
Cdd:smart00320   2 GELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
145-178 5.29e-06

WD domain, G-beta repeat;


Pssm-ID: 249832  Cd Length: 39  Bit Score: 42.73  E-value: 5.29e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 6680047    145 ESHSEWVSCVRFSPNSSnpIIVSCGWDKLVKVWN 178
Cdd:pfam00400   8 KGHTGPVTSVAFSPDGN--LLASGSDDGTVRVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
182-220 9.21e-06

WD domain, G-beta repeat;


Pssm-ID: 249832  Cd Length: 39  Bit Score: 41.96  E-value: 9.21e-06
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 6680047    182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWD 220
Cdd:pfam00400   1 GKLLRTLKGHTGPVTSVAFSPDGNLLASGSDDGTVRVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
145-178 3.01e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651  Cd Length: 40  Bit Score: 40.76  E-value: 3.01e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 6680047     145 ESHSEWVSCVRFSPNSSnpIIVSCGWDKLVKVWN 178
Cdd:smart00320   9 KGHTGPVTSVAFSPDGK--YLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
190-220 5.87e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651  Cd Length: 40  Bit Score: 39.99  E-value: 5.87e-05
                           10        20        30
                   ....*....|....*....|....*....|.
gi 6680047     190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWD 220
Cdd:smart00320  10 GHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
5-44 5.35e-04

WD domain, G-beta repeat;


Pssm-ID: 249832  Cd Length: 39  Bit Score: 36.95  E-value: 5.35e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 6680047      5 MTLRGTLKGHNGWVTQIATTPQfPDMILSASRDKTIIMWK 44
Cdd:pfam00400   1 GKLLRTLKGHTGPVTSVAFSPD-GNLLASGSDDGTVRVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
4-44 1.72e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651  Cd Length: 40  Bit Score: 35.75  E-value: 1.72e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 6680047       4 QMTLRGTLKGHNGWVTQIATTPQFpDMILSASRDKTIIMWK 44
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDG-KYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
286-310 4.19e-03

WD domain, G-beta repeat;


Pssm-ID: 249832  Cd Length: 39  Bit Score: 34.64  E-value: 4.19e-03
                          10        20
                  ....*....|....*....|....*
gi 6680047    286 CTSLAWSADGQTLFAGYTDNLVRVW 310
Cdd:pfam00400  14 VTSVAFSPDGNLLASGSDDGTVRVW 38
COG2319 COG2319
FOG: WD40 repeat [General function prediction only]
2-310 5.72e-41

FOG: WD40 repeat [General function prediction only]


Pssm-ID: 225201 [Multi-domain]  Cd Length: 466  Bit Score: 149.08  E-value: 5.72e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDEtnygiPQRALRGHSHFVSDVVISSDGQF-ALS 80
Cdd:COG2319 142 STPGKLIRTLEGHSESVTSLAFSPDGKLLASGSSLDGTIKLWDLRTGK-----PLSTLAGHTDPVSSLAFSPDGGLlIAS 216
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   81 GSWDGTLRLWDLTTGTTTR-RFVGHTKDVLSvAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPN 159
Cdd:COG2319 217 GSSDGTIRLWDLSTGKLLRsTLSGHSDSVVS-SFSPDGSLLASGSSDGTIRLWDLRSSSSLLRTLSGHSSSVLSVAFSPD 295
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047  160 SSnpIIVSCGWDKLVKVWNLAN--CKLKTNHIGHTGYLNTVTVSPDGSLCASGG-KDGQAMLWDLNEGKHLYTLDGGDII 236
Cdd:COG2319 296 GK--LLASGSSDGTVRLWDLETgkLLSSLTLKGHEGPVSSLSFSPDGSLLVSGGsDDGTIRLWDLRTGKPLKTLEGHSNV 373
                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6680047  237 NALCFSPNRYWLC-AATGPSIKIWDLEGKIIVDELKQEVISTsskaeppqcTSLAWSADGQTLFAGYTDNLVRVW 310
Cdd:COG2319 374 LSVSFSPDGRVVSsGSTDGTVRLWDLSTGSLLRNLDGHTSRV---------TSLDFSPDGKSLASGSSDNTIRLW 439
COG2319 COG2319
FOG: WD40 repeat [General function prediction only]
10-283 4.16e-38

FOG: WD40 repeat [General function prediction only]


Pssm-ID: 225201 [Multi-domain]  Cd Length: 466  Bit Score: 141.38  E-value: 4.16e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   10 TLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWkltrDETNYGIPQRALRGHSHFVSDVViSSDGQFALSGSWDGTLRL 89
Cdd:COG2319 193 TLAGHTDPVSSLAFSPDGGLLIASGSSDGTIRLW----DLSTGKLLRSTLSGHSDSVVSSF-SPDGSLLASGSSDGTIRL 267
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   90 WDL-TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNpIIVS 167
Cdd:COG2319 268 WDLrSSSSLLRTLSGHSSSVLSVAFSPDGKLLASGSSDGTVRLWDLeTGKLLSSLTLKGHEGPVSSLSFSPDGSL-LVSG 346
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047  168 CGWDKLVKVWNLANCKLKTNHIGHTGyLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIINALCFSPN-R 245
Cdd:COG2319 347 GSDDGTIRLWDLRTGKPLKTLEGHSN-VLSVSFSPDGRVVSSGSTDGTVRLWDLSTGSLLRNLDGhTSRVTSLDFSPDgK 425
                       250       260       270
                ....*....|....*....|....*....|....*...
gi 6680047  246 YWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEP 283
Cdd:COG2319 426 SLASGSSDNTIRLWDLKTSLKSVSFSPDGKVLASKSSD 463
COG2319 COG2319
FOG: WD40 repeat [General function prediction only]
32-315 1.58e-32

FOG: WD40 repeat [General function prediction only]


Pssm-ID: 225201 [Multi-domain]  Cd Length: 466  Bit Score: 125.20  E-value: 1.58e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   32 LSASRDKTIIMWKLTRDET--NYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFV--GHTKD 107
Cdd:COG2319  32 SLGSSESGILLLALLSDSLvsLPDLSSLLLRGHEDSITSIAFSPDGELLLSGSSDGTIKLWDLDNGEKLIKSLegLHDSS 111
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047  108 VLSVAFSSDNRQIV---SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNpIIVSCGWDKLVKVWNLANCKL 184
Cdd:COG2319 112 VSKLALSSPDGNSIllaSSSLDGTVKLWDLSTPGKLIRTLEGHSESVTSLAFSPDGKL-LASGSSLDGTIKLWDLRTGKP 190
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047  185 KTNHIGHTGYLNTVTVSPDGS-LCASGGKDGQAMLWDLNEGKHLY-TLDGGDIINALCFSPN-RYWLCAATGPSIKIWDL 261
Cdd:COG2319 191 LSTLAGHTDPVSSLAFSPDGGlLIASGSSDGTIRLWDLSTGKLLRsTLSGHSDSVVSSFSPDgSLLASGSSDGTIRLWDL 270
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....
gi 6680047  262 egkiivDELKQEVISTSSKAEPPqcTSLAWSADGQTLFAGYTDNLVRVWQVTIG 315
Cdd:COG2319 271 ------RSSSSLLRTLSGHSSSV--LSVAFSPDGKLLASGSSDGTVRLWDLETG 316
COG2319 COG2319
FOG: WD40 repeat [General function prediction only]
62-310 2.08e-26

FOG: WD40 repeat [General function prediction only]


Pssm-ID: 225201 [Multi-domain]  Cd Length: 466  Bit Score: 107.48  E-value: 2.08e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN-TLGVCKY 140
Cdd:COG2319  22 GPSLNSLSLLSLGSSESGILLLALLSDSLVSLPDLSSLLLRGHEDSITSIAFSPDGELLLSGSSDGTIKLWDlDNGEKLI 101
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047  141 TVQDESHSEWVSCVRFSPNSSNPIIVSCGW-DKLVKVWNLANC-KLKTNHIGHTGYLNTVTVSPDGSLCASGG-KDGQAM 217
Cdd:COG2319 102 KSLEGLHDSSVSKLALSSPDGNSILLASSSlDGTVKLWDLSTPgKLIRTLEGHSESVTSLAFSPDGKLLASGSsLDGTIK 181
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047  218 LWDLNEGKHLYTLDG-GDIINALCFSPNRYWLCAATGP--SIKIWDLE-GKIIVDELKQEVISTSSkaeppqctslAWSA 293
Cdd:COG2319 182 LWDLRTGKPLSTLAGhTDPVSSLAFSPDGGLLIASGSSdgTIRLWDLStGKLLRSTLSGHSDSVVS----------SFSP 251
                       250
                ....*....|....*..
gi 6680047  294 DGQTLFAGYTDNLVRVW 310
Cdd:COG2319 252 DGSLLASGSSDGTIRLW 268
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
80-222 1.11e-09

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 58.17  E-value: 1.11e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    80 SGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSS-DNRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHsewVSCVRFs 157
Cdd:PLN00181 550 SSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSaDPTLLASGSDDGSVKLWSiNQGVSIGTIKTKAN---ICCVQF- 625
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6680047   158 PNSSNPIIVSCGWDKLVKVWNLANCKLK-TNHIGHTGYLNTVTVSpDGSLCASGGKDGQAMLWDLN 222
Cdd:PLN00181 626 PSESGRSLAFGSADHKVYYYDLRNPKLPlCTMIGHSKTVSYVRFV-DSSTLVSSSTDNTLKLWDLS 690
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
31-261 1.79e-08

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 54.32  E-value: 1.79e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    31 ILSASRDKTIIMWKLTRDETnygipQRALRGHSHFVSDVVISS-DGQFALSGSWDGTLRLWDLTTGTTtrrfVGHTK--- 106
Cdd:PLN00181 548 VASSNFEGVVQVWDVARSQL-----VTEMKEHEKRVWSIDYSSaDPTLLASGSDDGSVKLWSINQGVS----IGTIKtka 618
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   107 DVLSVAFSSDN-RQIVSGSRDKTIKLWN----TLGVCKYTvqdeSHSEWVSCVRFSPNSSnpiIVSCGWDKLVKVWNLAN 181
Cdd:PLN00181 619 NICCVQFPSESgRSLAFGSADHKVYYYDlrnpKLPLCTMI----GHSKTVSYVRFVDSST---LVSSSTDNTLKLWDLSM 691
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   182 CKLKTNH------IGHTGYLNTVTVSPDGSLCASGGKDGQAMLW--------------DLNEGKHLYTLDGGDIINALCF 241
Cdd:PLN00181 692 SISGINEtplhsfMGHTNVKNFVGLSVSDGYIATGSETNEVFVYhkafpmpvlsykfkTIDPVSGLEVDDASQFISSVCW 771
                        250       260
                 ....*....|....*....|.
gi 6680047   242 SPNRYWLCAA-TGPSIKIWDL 261
Cdd:PLN00181 772 RGQSSTLVAAnSTGNIKILEM 792
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
108-314 4.22e-08

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 53.17  E-value: 4.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   108 VLSVAFSSDNRQIVSGSRDKTIKLWNtlgvCKYTVQD--ESHSEWVSCVRFSPNSS-------NPIIVSCGWDKLVKVWN 178
Cdd:PLN00181 486 VCAIGFDRDGEFFATAGVNKKIKIFE----CESIIKDgrDIHYPVVELASRSKLSGicwnsyiKSQVASSNFEGVVQVWD 561
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   179 LANCKLKTNHIGHTGYLNTVTVSP-DGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSpnrywlcAATGPSIK 257
Cdd:PLN00181 562 VARSQLVTEMKEHEKRVWSIDYSSaDPTLLASGSDDGSVKLWSINQGVSIGTIKTKANICCVQFP-------SESGRSLA 634
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 6680047   258 IWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTI 314
Cdd:PLN00181 635 FGSADHKVYYYDLRNPKLPLCTMIGHSKTVSYVRFVDSSTLVSSSTDNTLKLWDLSM 691
PTZ00421 PTZ00421
coronin; Provisional
102-213 9.68e-07

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 48.74  E-value: 9.68e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047   102 VGHTKDVLSVAFSS-DNRQIVSGSRDKTIKLWN------TLGVCKYTVQDESHSEWVSCVRFSPnSSNPIIVSCGWDKLV 174
Cdd:PTZ00421  72 LGQEGPIIDVAFNPfDPQKLFTASEDGTIMGWGipeeglTQNISDPIVHLQGHTKKVGIVSFHP-SAMNVLASAGADMVV 150
                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 6680047   175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKD 213
Cdd:PTZ00421 151 NVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKD 189
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
11-133 1.27e-04

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 42.38  E-value: 1.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLtrdetNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Cdd:PLN00181 571 MKEHEKRVWSIDYSSADPTLLASGSDDGSVKLWSI-----NQGVSIGTIKTKANICCVQFPSESGRSLAFGSADHKVYYY 645
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 6680047    91 DLTTGTTTR-RFVGHTKDVLSVAFsSDNRQIVSGSRDKTIKLWN 133
Cdd:PLN00181 646 DLRNPKLPLcTMIGHSKTVSYVRF-VDSSTLVSSSTDNTLKLWD 688
PTZ00421 PTZ00421
coronin; Provisional
11-131 1.33e-04

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 41.80  E-value: 1.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRD--ETNYGIPQRALRGHSHFVSDVVI--SSDGQFALSGSwDGT 86
Cdd:PTZ00421  71 LLGQEGPIIDVAFNPFDPQKLFTASEDGTIMGWGIPEEglTQNISDPIVHLQGHTKKVGIVSFhpSAMNVLASAGA-DMV 149
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 6680047    87 LRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKL 131
Cdd:PTZ00421 150 VNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNI 194
PTZ00420 PTZ00420
coronin; Provisional
11-92 1.24e-03

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 39.16  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6680047    11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYG---IPQRALRGHSHFVSDVVISSDGQFAL-SGSWDGT 86
Cdd:PTZ00420  70 LKGHTSSILDLQFNPCFSEILASGSEDLTIRVWEIPHNDESVKeikDPQCILKGHKKKISIIDWNPMNYYIMcSSGFDSF 149

                 ....*.
gi 6680047    87 LRLWDL 92
Cdd:PTZ00420 150 VNIWDI 155
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.12
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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