NCBI Conserved Domain Search

NewSearch

CDD Home

Conserved domains on [gi\|46198730\|ref\|YP_004397.1\|]
sensory transduction histidine kinase [Thermus thermophilus HB27]

Graphical summary show options »	Show site features Horizontal zoom: ×	?



List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH

of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

30163

cd01948

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

true

false

true

240

1e-49

193.12

99.17

6,460,2,38,498,41,27,525,69,7,532,82,18,550,106,29,579,137,103

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 461 LEKALAEGELRLYGQPIVDLATGRPAGVEVLLRWARGE-EVVPASRFIPVAEEAGLIPELDLYVLR-ALAQMTT------ 532
cd01948       3 LRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEgGLISPAEFIPLAEETGLIVELGRWVLEeACRQLARwqaggp 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 533 ALPLHVNLSPQTLLDERL------LLGLAPLKGRNLRLELTEHALASPGAEAR--LKELSCMGFPVVLDDFGQGYASLRL 604
cd01948      83 DLRLSVNLSARQLRDPDFldrlleLLAETGLPPRRLVLEITESALIDDLEEALatLRRLRALGVRIALDDFGTGYSSLSY 162

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 46198730 605 LVGLPFSMAKVDRGFVGGIGLDPKAEAALKAVLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQGYLWGRPAPLEE 682
cd01948     163 LKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAEE 240

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

133472

cd01949

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as domain of unknown function 1 (DUF1). It is widely present in bacteria and often links to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain has been suggested to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesiveness in bacteria.

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

true

false

true

157

3e-23

105.36

97.45

4,292,0,24,316,31,57,373,89,22,396,111,42

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 293 HDPLTGLPNRRRLEEDFRLLRGRW-------ALCRLDLVDLYEVNEAYGREAGDALLARTSRRLQALLPREGRLYRLEGG 365
cd01949       1 TDPLTGLPNRRAFEERLERLLARArrsgrplALLLIDLDHFKQINDTYGHAAGDEVLKEVARRLRSSLRESDLVARLGGD 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46198730 366 EFLALLPG-GAKEAEAFGQALGEALEAPLDLgEGRAFRVRVRAGVALFPDDANTLSELLRRADQALREAKKAGK 438
cd01949      81 EFAILLPGtDLEEAEELAERLRKAIEEPFFI-DGEEIRVTASIGIAEYPEDGEDLEELLRRADKALYQAKRSGR 153

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

128367

smart00052

EAL

Putative diguanylate phosphodiesterase

false

241

1e-48

189.73

98.76

7,460,3,34,494,39,9,504,48,21,525,70,5,530,81,20,550,107,21,571,130,111

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 461 LEKALAEGELRLYGQPIVDLATGRPAGVEVLLRW--ARGEEVVPAsRFIPVAEEAGLIPELDLYVLR-ALAQM------T 531
smart00052    4 LRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWqhPEGGIISPD-EFIPLAEETGLIVPLGRWVLEqACQQLaewqaqG 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 532 TALPLHVNLSPQTLLDERL------LLGLAPLKGRNLRLELTEHAL--ASPGAEARLKELSCMGFPVVLDDFGQGYASLR 603
smart00052   83 PPLRISINLSARQLISPDLvprvleLLEETGLPPQRLELEITESVLldDDESAVATLQRLRELGVRIALDDFGTGYSSLS 162

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 46198730 604 LLVGLPFSMAKVDRGFVGGIGLDPKAEAALKAVLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQGYLWGRPAPLEE 682
smart00052  163 YLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPLDD 241

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

32382

COG2200

Rtn

c-di-GMP phosphodiesterase class I (EAL domain) [Signal transduction mechanisms]

false

256

7e-47

183.99

95.70

6,453,0,41,494,42,31,525,74,7,532,86,18,550,110,23,573,135,110

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 454 RREVLAGLEKALAEGELRLYGQPIVDLATGRPAGVEVLLRW-ARGEEVVPASRFIPVAEEAGLIPELDLYVLR-ALAQMT 531
COG2200       1 RLQLERDLRQALENGEFSLYYQPIVDLATGRIVGYEALLRWrHPDGGLISPGEFIPLAEETGLIVELGRWVLEeACRQLR 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 532 T-----ALPLHVNLSPQTLLDERL------LLGLAPLKGRNLRLELTEHALAS--PGAEARLKELSCMGFPVVLDDFGQG 598
COG2200      81 TwpragPLRLAVNLSPVQLRSPGLvdlllrLLARLGLPPHRLVLEITESALIDdlDTALALLRQLRELGVRIALDDFGTG 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 599 YASLRLLVGLPFSMAKVDRGFVGGIGLDPKAEAALKAVLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQGYLWGRPA 678
COG2200     161 YSSLSYLKRLPPDILKIDRSFVRDLETDARDQAIVRAIVALAHKLGLTVVAEGVETEEQLDLLRELGCDYLQGYLFSRPL 240


                ....*
gi 46198730 679 PLEEV 683
COG2200     241 PADAL 245

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

109613

pfam00563

EAL

EAL domain

false

236

4e-45

178.00

98.73

7,460,3,34,494,38,31,525,70,8,533,87,18,551,110,20,571,131,52,624,183,53

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 461 LEKALAEGELRLYGQPIVDLATGRPAGVEVLLRW-ARGEEVVPASRFIPVAEEAGLIPELDLYVLR-ALAQMTTA----- 533
pfam00563     4 LREALENGEFSLYFQPIVDLRTGKVLGYEALLRWqHPDGGLIPPDEFLPLAERLGLIAELDRWVLEkALAQLAEWrgnal 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 534 ----LPLHVNLSPQTLLDERLL-----LGLAPLKGRNLRLELTEHAL-ASPGAEARLKELSCMGFPVVLDDFGQGYASLR 603
pfam00563    84 lppdLPLSVNLSPASLLDPSFLeallaLKQGGLPPSRLVLEITESDLdEDLRLLEALARLRSLGFRLALDDFGTGYSSLS 163

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 46198730 604 LLVGLPFSMAKVDRGFVGGIgLDPKAEAALKAVLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQGYLWGRP 677
pfam00563   164 YLSRLPPDYIKIDRSFIKDL-SDPESRALLRALIALARELGIKVVAEGVETEEQLELLKELGIDYVQGYLFSKP 236

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

128563

smart00267

GGDEF

diguanylate cyclase

false

163

2e-17

86.15

98.16

5,291,3,24,315,34,58,373,93,22,396,115,42,438,158,5

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 292 YHDPLTGLPNRRRLEEDFRLLRGR-------WALCRLDLVDLYEVNEAYGREAGDALLARTSRRLQALLPREGRLYRLEG 364
smart00267    4 FRDPLTGLPNRRYFEEELEQELQRaqrqgspFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRPGDLLARLGG 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 365 GEFLALLPG-GAKEAEAFGQALGEALEAPLDLgEGRAFRVRVRAGVALFPDDANTLSELLRRADQALREAKKAGK-RWTF 442
smart00267   84 DEFALLLPEtSLEEAIALAERILQQLREPIII-HGIPLYLTISIGVAAYPNPGEDAEDLLKRADTALYQAKKAGRnQVAV 162


                .
gi 46198730 443 Y 443
smart00267  163 Y 163

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

110022

pfam00990

GGDEF

GGDEF domain

false

160

2e-17

86.14

98.75

6,291,1,21,315,22,7,322,36,5,327,44,46,373,94,22,396,116,43

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 292 YHDPLTGLPNRRRLEEDFRLLrgrWALCRLD-------LVDLY---EVNEAYGREAGDALLARTSRRLQALLPREGRLYR 361
pfam00990     2 AHDPLTGLPNRRYFEEELEQE---LQRAQRRqsplallLLDLDnfkRINDTYGHAVGDEVLQEVAQRLSSSLRRSDLVAR 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 362 LEGGEFLALLPG----GAKEAEAFGQALGEALEAPLDLgEGRAFRVRVRAGVALFPDDANTLSELLRRADQALREAKKAG 437
pfam00990    79 LGGDEFAILLPDtsleGAQELAERIRRLLAALKIPHTL-SGLPLYVTISIGIAAYPNDGEDAEDLLKRADQALYQAKNQG 157


                ..
gi 46198730 438 KR 439
pfam00990   158 RN 159

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

32381

COG2199

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction...

false

181

3e-17

85.56

88.95

4,291,20,25,316,52,57,373,110,65,438,176,5

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 292 YHDPLTGLPNRRRLEEDFRLLRGRW-------ALCRLDLVDLYEVNEAYGREAGDALLARTSRRLQALLPREGRLYRLEG 364
COG2199      21 LHDPLTGLPNRRAFEERLERALARArrhgeplALLLLDLDHFKQINDTYGHAAGDEVLREVARRLRSNLREGDLVARLGG 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 365 GEFLALLPG-GAKEAEAFGQALGEALEAPLDLGEGRAFRVRVRAGVALFPDDANTLSELLRRADQALREAKKAGK-RWTF 442
COG2199     101 DEFAVLLPGtSLEEAARLAERIRAALEEPFFLGGEELRVTVSIGVALYPEDGSDDAELLLRRADLALYRAKRAGRnRVVV 180


                .
gi 46198730 443 Y 443
COG2199     181 F 181

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

129356

TIGR00254

GGDEF

diguanylate cyclase (GGDEF) domain

false

165

1e-10

63.51

98.18

6,291,2,21,315,23,7,322,37,4,326,44,54,380,99,11,391,111,53

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 292 YHDPLTGLPNRRRLEEDFRLLrgrWALCRLD-------LVDL---YEVNEAYGREAGDALLARTSRRLQALLPREGRLYR 361
TIGR00254     3 VRDPLTGLYNRRYLEEMLDSE---LKRARRFqrsfsvlMIDIdnfKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGR 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 362 LEGGEFLALLPGGAKEAEA-FGQALGEALEA-PLDLGEGRAFRVRVRAGVALFPDDANTLSELLRRADQALREAKKAGKR 439
TIGR00254    80 YGGEEFVVILPGTPLEDALsKAERLRDAINSkPIEVAGSETLTVTVSIGVACYPGHGLTLEELLKRADEALYQAKKAGRN 159


                ....*
gi 46198730 440 WTFYS 444
TIGR00254   160 RVVVA 164

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

110584

pfam01590

GAF

GAF domain

true

false

153

2e-10

63.03

97.39

4,142,1,11,153,17,17,173,34,49,222,97,53

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 143 LHKVCALLVEE-----GYALAWVGEARPTGEVVpreAAGAVGYLEGIRVRWDEAPEGQGPTGRALRSGRPQVLRSVEEDP 217
pfam01590     2 LEELLQTILEElrellGADRCAILLADADGLLL---YLVAGDGLSDIPLAARGLPLGGGVVGEVIAGGNPIVVPDVQDDP 78

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 46198730 218 RYAPW--------------RERAQVFGFASSAAFPLRVEGRVWGSLNVYAPEEDAFDEEEVRLLEDLARLIG 275
pfam01590    79 RFRDLtalaeelpapvgchEHYLRGLGIRSCLAVPLLGGGKLIGVLVLHSTSPRAFTEEELELLQALADQVA 150

cl00853

140972

GAF

GAF domain

-1

128379

smart00065

GAF

Domain present in phytochromes and cGMP-specific phosphodiesterases.

false

149

4e-09

58.54

70.47

5,165,31,25,195,56,23,220,79,12,232,92,24,256,117,19

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 166 TGEVVPREAAGAVGYLEGIRVRWDEapegqGPTGRALRSGRPQVLRSVEEDPRyaPWRERAQVFGFA-SSAAFPLRVEGR 244
smart00065   32 RGELVLVAADGLTLPLLGLRYPLGE-----GLAGRVAETGRPLNIPDVEADPV--FALDLLGRYQGVrSFLAVPLVADGE 104

                        90       100       110
                ....*....|....*....|....*....|..
gi 46198730 245 VWGSLNVYAPEE-DAFDEEEVRLLEDLARLIG 275
smart00065  105 LVGVLALHNKDSpRPFTEEDEELLQALANQLA 136

cl00853

140972

GAF

GAF domain

-1

32385

COG2203

FhlA

FOG: GAF domain [Signal transduction mechanisms]

false

175

2e-07

52.71

82.86

4,134,14,19,153,34,25,178,61,78,256,140,19

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 135 QAAGEGDLLHKVCALLVEE-GYALAWVGEARPTGEVVPREAAGAV--GYLEGIRVRWDEAPEGQGPTGRALRSGRPQVLR 211
COG2203      15 QDLDLEEILQAALELLAELlGADRGLIYLLDEDGLLDGALVAEAAeaGLEQLIDELFGLVILPACLIGIALREGRPVVVE 94

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 46198730 212 SVEEDPRYAPWRERAQVFGFASSAAFPLRVEGRVWGSLNVYAPEE-DAFDEEEVRLLEDLARLIG 275
COG2203      95 DILQDPRFRDNPLVLLEPPIRSYLGVPLIAQGELLGLLCVHDSEPrRQWSEEELELLEELAEQVA 159

cl00853

140972

GAF

GAF domain

-1

138661

PRK11596

EAL domain-containing protein; Provisional

false

255

6e-04

41.62

56.08

6,537,103,24,561,129,16,577,146,7,588,153,30,618,184,30,649,214,32

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 538 VNLSPQTLLDERLLLGLAPLKGRN--LRLELTEHALASPGAE-ARLKELScmgfPVVLDDFGQGYASLRLLVGLPFSMAK 614
PRK11596    104 VNIDGPTLIALRQQPKILRLIERLpwLRFELVEHIRLPKDSTfASMCEFG----PLWLDDFGTGMANFSALSEVRYDYIK 179

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 46198730 615 VDRG-FVGGIGLDPKAEAALKAVLALSRELEIALVaEGVEREDQWAWLRSVGYSLGQGYLWGRPAPLE 681
PRK11596    180 VARElFVMLRQSPEGRTLFSQLLHLMNRYCRGVIV-EGVETPEEWRDVQRSPAFAAQGYFLSRPAPFD 246

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

32139

COG1956

GAF domain-containing protein [Signal transduction mechanisms]

false

163

0.002

39.87

73.62

4,142,36,33,177,69,9,191,78,36,232,114,42

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 143 LHKVCALLVEEGYALAWVGEARPTGEVVPREAAgaVGYLEGIRVrwdeaPEGQGPTGRALRSGRPQVLRSVEEDPRYAPW 222
COG1956      37 LANASALLKERLPDVNWVGFYLLEGDELVLGPF--QGKVACVRI-----PFGKGVCGTAAATGETVRVDDVHAFPGHIAC 109

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 46198730 223 RERAQvfgfaSSAAFPLRVEGRVWGSLNVYAPEEDAFDEEEVRLLEDLARLI 274
COG1956     110 DAASN-----SEIVVPIFKDGKLIGVLDIDSPTPGRFDEEDEAGLEKLAALL 156

cl00853

140972

GAF

GAF domain

-1

34606

COG5001

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF...

false

true

false

663

1e-50

196.78

61.99

10,293,230,22,315,259,64,379,325,30,410,355,28,438,384,61,499,446,25,524,472,8,532,483,22,554,511,25,579,538,103

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 294 DPLTGLPNRRRLEEDFRLLRGR-------WALCRLDLVDLYEVNEAYGREAGDALLARTSRRLQALLPREGRLYRLEGGE 366
COG5001     231 DSLTGLPNRRRFFAELDARLAAarqsgrrLVLGVIDLDGFKPVNDAFGHATGDRLLIEVGRRLKAFDGAPILAARLGGDE 310

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 367 FLALLPGGAKEAE--AFGQALGEALEAPLDLGEGRAFRVRVRAGVaLFPDDANTLSELLRRADQALREAKKAGK-RWTFY 443
COG5001     311 FALIIPALEDDALrvAGARALCESLQAPYDLRGVRVQVGASIGIA-PFPSGADTSEQLFERADYALYHAKQNGKgAAVLF 389

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 444 SLGLGEAVRERREVLAGLEKALAEGELRLYGQPIVDLATGRPAGVEVLLRWARGEE-VVPASRFIPVAEEAGLIPELDLY 522
COG5001     390 DARHEAAIRDMAVVEQALRSADLEQELSVHFQPIVDIVSGKTIALEALARWHSPEIgPVPPDVFIGIAERSGQIVELTRL 469

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 523 VL-RALAQMTT---ALPLHVNLSPQTLLDERLLLGL------APLKGRNLRLELTEHALASPGAEAR--LKELSCMGFPV 590
COG5001     470 LLaKALREARAwpmDVRVSINLSARDLASMENVRRLlaivseSCIAPHRLDFEITETAIVCDFDQARdaLAALHELGVRT 549

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 591 VLDDFGQGYASLRLLVGLPFSMAKVDRGFVGGIGLDPKAEAALKAVLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQ 670
COG5001     550 ALDDFGTGYSSLSHLRALPLDKIKIDRSFVSDLEENPTSEDIVRTVLQLGRNLRMECVVEGVETEAQRDRVAALGATVMQ 629

                       410
                ....*....|..
gi 46198730 671 GYLWGRPAPLEE 682
COG5001     630 GYHYARPMPAEE 641

-1

137662

PRK10060

RNase II stability modulator; Provisional

false

true

false

663

9e-44

173.76

61.84

11,293,239,24,317,268,61,378,330,31,410,361,29,439,391,41,481,432,18,499,451,34,533,492,23,556,516,7,563,528,16,579,546,103

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 294 DPLTGLPNRRRLEEDFRLLRGRWA-----LCRLDLVDLYEVNEAYGREAGDALLARTSRRLQALLPREGRLYRLEGGEFL 368
PRK10060    240 DSITGLPNRNAIQELIDHAIAQADnnqvgIVYLDLDNFKKVNDAYGHMFGDQLLQDVSLAILSCLEEDQTLARLGGDEFL 319

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 369 ALLPGGAKEA-EAFGQALGEALEAPLDLGEGRAFRVRVRAGVaLFPDDANTLSELLRRADQALREAKKAGKR-WTFYSLG 446
PRK10060    320 VLASHTSQAAlEAMASRILTRLRLPFRIGLIEVYTGCSIGIA-LSPEHGDDSESLIRSADTAMYTAKEGGRGqFCVFSPE 398

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 447 LGEAVRERREVLAGLEKALAEGELRLYGQPIVDLaTGRPAGVEVLLRWARGEE-VVPASRFIPVAEEAGLIPELDLYVLR 525
PRK10060    399 MNQRVFEYLWLDTNLRKALENDQLVIHYQPKITW-RGEVRSLEALVRWQSPERgLIPPLEFISYAEESGLIVPLGRWVIL 477

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 526 ALAQMTTA-------LPLHVNLSPQTLLDERLLLGLAP-LKGRNLR-----LELTEHALASPGAEAR--LKELSCMGFPV 590
PRK10060    478 DVVRQAAKwrdkginLRVAVNVSARQLADQTIFTALKQvLQELNFEycpidVELTESCLIENEELALsvIQQFSQLGAQV 557

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 591 VLDDFGQGYASLRLLVGLPFSMAKVDRGFVGGIGLDPKAEAALKAVLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQ 670
PRK10060    558 HLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVETAKEDAFLTKNGVNERQ 637

                       410
                ....*....|..
gi 46198730 671 GYLWGRPAPLEE 682
PRK10060    638 GFLFAKPMPAVA 649

-1

138538

PRK11359

cAMP phosphodiesterase; Provisional

false

true

false

799

1e-41

166.55

51.19

11,293,378,22,315,403,59,374,463,45,422,508,15,437,524,62,499,587,26,525,614,6,531,626,4,535,631,15,550,652,27,577,681,106

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 294 DPLTGLPNRRRLEEDFRLLRGR---WALCRLDLVDLYEVNEAYGREAGDALLARTSRRLQALLPREGRLYRLEGGEFLAL 370
PRK11359    379 DPMTGLPNRNNLHNYLDDLVDKavsPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRIEGTQFVLV 458

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 371 LPGG-AKEAEAFGQALGEALEAPLDLGEGRAFRVRVRAGVALFPDDANTLselLRRADQALREAKKAG-KRWTFYSLGLG 448
PRK11359    459 SLENdVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISYDVGKNRDYL---LSTAHNAMDYIRKNGgNGWQFFSPAMN 535

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 449 EAVRERREVLAGLEKALAEGELRLYGQPIVDLATGRPAGVEVLLRWARGEE-VVPASRFIPVAEEAGLIPELDLYVLR-A 526
PRK11359    536 EMVKERLVLGAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHgHVPPSRFIPLAEEIGEIENIGRWVIAeA 615

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 527 LAQMT------TALP-LHVNLSPQTLLDERL------LLGLAPLKGRNLRLELTEHALASPGAE--ARLKELSCMGFPVV 591
PRK11359    616 CRQLAewrsqnIHIPaLSVNLSALHFRSNQLpnqvsdAMHAWGIDGHQLTVEITESMMMEHDTEifKRIQILRDMGVGLS 695

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 592 LDDFGQGYASLRLLVGLPFSMAKVDRGFVGGIGLDPKAEAALKAVLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQG 671
PRK11359    696 VDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQG 775

                       410
                ....*....|..
gi 46198730 672 YLWGRPAPLEEV 683
PRK11359    776 YFFSRPLPAEEI 787

-1

34551

COG4943

Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]

Predicted signal transduction protein containing sensor and EAL domains [Signal...

false

true

false

524

8e-37

150.49

47.33

7,451,263,47,498,311,26,524,338,13,537,357,14,551,377,27,578,408,5,586,413,98

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 452 RERREVLAGLEKALAEGELRLYGQPIVDLATGRPAGVEVLLRWARGE-EVVPASRFIPVAEEAGLIPELDLYVL-RALAQ 529
COG4943     264 RRYLSPRRRLQRAIERRELCVHYQPIVDLATGKCVGAEALARWPQEDgTVVSPDVFIPLAEESGMIEQITDYVIrNVFRD 343

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 530 MTTALPLH------VNLSPQTLLDERLL------LGLAPLKGRNLRLELTEHALASPGAEA----RLKELscmGFPVVLD 593
COG4943     344 LGDLLRQHrdlhvsINLSASDLASPRLIdrlnrkLAQYQVRPQQIALELTERTFADPKKMTpiilRLREA---GHEIYID 420

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 594 DFGQGYASLRLLVGLPFSMAKVDRGFVGGIGLDPKAEAALKAVLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQGYL 673
COG4943     421 DFGTGYSNLHYLQSLPVDALKIDKSFVDTLGTDSASHLIAPHIIEMAKSLGLKIVAEGVETEEQVDWLRKRGVHYGQGWL 500

                       250
                ....*....|.
gi 46198730 674 WGRPAPLEEVL 684
COG4943     501 FSKALPAQAFL 511

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

6e-35

144.08

37.54

11,292,689,23,315,719,58,373,778,65,438,844,20,458,866,33,491,900,2,493,903,36,529,949,10,539,960,11,550,972,29,579,1003,105

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730  293 HDPLTGLPNRRRLEEDFRLLRGR-------WALCRLDLVDLYEVNEAYGREAGDALLARTSRRLQALLPREGRLYRLEGG 365
PRK09776     690 HDALTGLANRASFEKQLREALQTvnsthqrHALVFIDLDRFKAVNDSAGHAAGDALLRELASLMLSMLRSSDVLARLGGD 769

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730  366 EFLALLPG-GAKEAEAFGQALGEALEAPLDLGEGRAFRVRVRAGVALFPDDANTLSELLRRADQALREAKKAGK-RWTFY 443
PRK09776     770 EFGLLLPDcNVESARFIATRIISAINDYRFPWEGRVYRVGASAGITAIDDNNHQASEVMSQADIACYAAKNAGRgRVTVY 849

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730  444 SLGLGEAVRERREVL--AGLEKALAEGELRLYGQPIVDLATGRPAGVEVL-LR-WARGEEVVPASRFIPVAEEAGLIPEL 519
PRK09776     850 EPQQAAAHSERRELSlaEQWRSMLEENQLMLQAQEIASPRIPEARNLWLIsLRlWDCEGEIIDEGAFRPAAEDPALMHAL 929

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730  520 DLYVLRALAQ----------MTTALPLHVN-LSPQTLLDERL-LLGLAPLKGRNLRLELTEHALASPGAEAR--LKELSC 585
PRK09776     930 DRWVIHELFQqgaravaskgLSIAIPLSVAsLSSATLLPFLLeQLENSPLPPRLLHLEITETALLNHAEAASrlVQKLRL 1009

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730  586 MGFPVVLDDFGQGYASLRLLVGLPFSMAKVDRGFVGGIGLDPKAEAALKAVLALSRELEIALVAEGVEREDQWAWLRSVG 665
PRK09776    1010 AGCRVVLDDFGRGLSSFNYLKAFMADYLKIDGELCANLQGNLMDEMLVSIINGIAQRLGMKTIAGPVELPLTLDTLSGIG 1089

                        410
                 ....*....|....*....
gi 46198730  666 YSLGQGYLWGRPAPLEEVL 684
PRK09776    1090 VDLAQGYVIGRPQPLDLLL 1108

-1

139666

PRK13561

putative phosphodiesterase; Provisional

false

true

false

651

2e-33

139.13

55.45

14,338,281,29,368,310,9,377,322,38,417,360,21,438,382,58,496,442,8,505,450,19,524,473,4,528,480,32,560,518,10,570,529,4,574,534,31,605,568,18,626,586,56

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 339 DALLARTSRRLQALLPREGRLYRLEGGEFlALLPGGAKE---AEAFGQALGEALEAPLDLGEGRAFRVRVRAGVALFPDD 415
PRK13561    282 EILLLTLVEKLKSVLSPRMVLAQISGYDF-AIIANGVKEpwhAITLGQQVLTIINERLPIQRIQLRPSCSIGIAMFYGDL 360

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 416 anTLSELLRRADQALREAKKAGK-RWTFYSLGLGEAVRERREVLAGLEKALAEGELRLYGQPIVDLATGRPAGVEVLLRW 494
PRK13561    361 --TAEQLYSRAVSAAFTARRKGKnQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMRSGKLVSAEALLRM 438

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 495 AR--GEEVVPASrFIPVAEEAGLIPELDLYVL----RALA---QMTTALPLHVNLSPQTLLDERLLLGLAPLKGR----- 560
PRK13561    439 QQpdGSWDLPDG-LIDRIESCGLMVTVGHWVLeescRLLAawqERGIMLPLSVNLSALQLMHPNMVADMLELLTRyriqp 517

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 561 -NLRLELTEHA-LASP-GAEARLKELSCMGFPVVLDDFGQGYASLRLL---VGLPFSMAKVDRGFVGGIgldPKAEAALK 634
PRK13561    518 gTLILEVTESRrIDDPhAAVAILRPLRNAGVRIALDDFGMGYAGLRQLqhmKSLPIDVLKIDKMFVDGL---PEDSSMVA 594

                       330       340       350       360
                ....*....|....*....|....*....|....*....|....*...
gi 46198730 635 AVLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQGYLWGRPAPLEE 682
PRK13561    595 AIIMLAQSLNLQMIAEGVETEAQRDWLAKAGVGVAQGFLFARPLPIEI 642

-1

137979

PRK10551

hypothetical protein; Provisional

false

true

false

518

5e-30

128.25

46.91

8,451,262,12,467,274,27,494,304,4,500,308,28,528,340,7,535,351,13,548,370,34,582,405,100

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 452 RERREVLAGLEKalaeGELRLYGQPIVDLATGRPAGVEVLLRW---ARGEevVPASRFIPVAEEAGLIPELDLYVLRALA 528
PRK10551    263 RPGREILTAIKR----EQFYVVYQPVVDTQTLRVTGLEVLLRWrhpTAGE--IPPDAFINYAEAQKLIVPLTQHLFELIA 336

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 529 ----QMTTALP----LHVNLSPQTLLDE------RLLLGLAPLKGRNLRLELTEHALASPGAEARLKE-LSCMGFPVVLD 593
PRK10551    337 rdaaELQKVLPvgakLGINIAPAHLHSDsfkadvQRLLASLPADHFQIVLEITERDMLQEEEALKLFAwLHSQGIEIAID 416

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 594 DFGQGYASLRLLVGLPFSMAKVDRGFVGGIGLDPKAEAALKAVLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQGYL 673
PRK10551    417 DFGTGHSALIYLERFTLDYLKIDRGFINAIGTETVTSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLREHGVNFLQGYW 496


                ....*....
gi 46198730 674 WGRPAPLEE 682
PRK10551    497 ISRPLPLDD 505

-1

138768

PRK11829

biofilm formation regulator HmsP; Provisional

false

true

false

728

4e-24

108.25

38.87

10,416,432,26,442,459,54,496,515,6,503,521,21,524,546,8,532,557,25,557,588,22,579,612,26,605,641,18,626,659,56

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 417 NTLSELLRRADQALREAKKAGKRWTF-YSLGLGEAVRERREVLAGLEKALAEGELRLYGQPIVDLATGRPAGVEVLLRWA 495
PRK11829    433 DTAESMMRNASTAMMAAHHEGRNQIMvFEPHLIEKTHKRLTQENDLLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWC 512

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 496 R--GEEVVPaSRFIPVAEEAGLIPELDLYVL----RALAQMTT---ALPLHVNLSPQTLLDERLLLGLAPL------KGR 560
PRK11829    513 QpdGSYVLP-SGFVHFAEEEGMMVPLGNWVLeeacRILADWKArgvSLPLSVNISGLQVQNKQFLPHLKTLishyhiDPQ 591

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 561 NLRLELTEHALASPGAEAR--LKELSCMGFPVVLDDFGQGYASLRLL---VGLPFSMAKVDRGFVGGIgldPKAEAALKA 635
PRK11829    592 QLLLEITETAQIQDLDEALrlLRELQGLGLLIALDDFGIGYSSLRYLnhlKSLPIHMIKLDKSFVKNL---PEDDAIARI 668

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*..
gi 46198730 636 VLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQGYLWGRPAPLEE 682
PRK11829    669 ISCVSDVLKVRVMAEGVETEEQRQWLLEHGIQCGQGFLFSPPLPRAE 715

-1

138376

PRK11059

regulatory protein CsrD; Provisional

false

true

false

642

2e-13

72.61

58.72

15,320,264,35,355,301,18,373,320,18,391,343,19,417,362,20,437,389,11,449,400,5,458,405,21,480,426,20,500,447,20,520,471,11,531,483,20,559,503,11,570,520,8,578,539,102

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 321 LDLVDLYEVNEAYGREAGDALLARTSRRLQALLPR--EGRLYRLEGGEFLALLPG-GAKEAEAFGQALGEALEA-----P 392
PRK11059    265 IRLPDFDLLQEELGESQVDELLFELINLLSTFVQRypGALLARYSRSDFAVLLPHrSLKEADSLASQLLKAVDSlpppkM 344

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 393 LDLGEGRAFRVRVRAGVAlfpddanTLSELLRRADQALREAKKAG-------KRWTFYSLGLGeAVRERrevlAGLEKAL 465
PRK11059    345 LDRDDFLHIGIAAYRSGQ-------STEQVMEEAEMALRSAQLQGgnswfmyDKAQDPEKGRG-SVRWR----TLLEQAL 412

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 466 AEGELRLYGQPIVDlATGRPAGVEVLLRWARGEEV-VPASRFIPVAEEAGLIPELD----LYVLRALAQMT-TALPLHVN 539
PRK11059    413 VRGGPRLYQQPVVT-RDGQVHHRELMCRIRDGQGNeVRAAEFMPMVLQCGLSEQYDrqviERVLPLLSYWPeESQNLSIN 491

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 540 LSPQTLLDERLLlglaplkgRNLRLELTEHA------LASPGAEA-----------RLKELSCMGFPVVLDDFGQGYASL 602
PRK11059    492 LSVDSLLSRAFQ--------RWLRDTLLQCErsqrkrLIFELAEAdvvqhidrlrpVLRMLRGLGCRLAVDQAGLTVVST 563

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 46198730 603 RLLVGLPFSMAKVDRGFVGGIGLDPKAEAALKAVLALSRELEIALVAEGVEREDQWAWLRSVGYSLGQGYLWGRPAPL 680
PRK11059    564 SYIKELNVELIKLHPSLVRNIHQRTENQLFVRSLVGACAGTETQVFAEGVESREEWQTLQILGVSGGQGDFFASPQPL 641

-1

137576

PRK09894

hypothetical protein; Provisional

false

true

false

293

2e-08

56.64

51.19

5,293,132,22,315,159,60,375,220,16,391,237,24,417,261,21

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 294 DPLTGLPNRRRLEEDFRLLRGR-----WALCRLDLVDLYEVNEAYGREAGDALLARTSRRLQALLPREGRLYRLEGGEFL 368
PRK09894    133 DVLTGLPGRRVLDESFDHQLRNreplnLYLALLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRPYETVYRYGGEEFI 212

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 46198730 369 ALLPGGA-KEAEAFGQALGEALEA-PLDLGEGRAFRVRVRAGVALFPDDanTLSELLRRADQALREAKKAGK 438
PRK09894    213 IILKAATdEEACRAGERIRQLIANqAITHSEGRINITATFGVTRAFPEE--PLDEVIGRADRAMYEGKQAGR 282

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

4e-07

51.84

35.86

5,292,271,23,315,301,62,377,368,10,388,378,27,416,405,22

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 293 HDPLTGLPNRRRLEEDFRLLRGR-------WALCRLDLVDLYEVNEAYGREAGDALLARTSRRLQALLPREGRLYRLEGG 365
COG3706     272 VDGLTGLFNRRYFDEHLADLWKRalregrpLSLLMLDIDDFKEINDTYGHDVGDEVLRQVARRLRQTVRGLDLVARYGGE 351

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 46198730 366 EFLALLPGGAKE-----AEAFGQALGEaLEAPLDLGEGRAFRVRVRAGVALFPDDaNTLSELLRRADQALREAKKAGK 438
COG3706     352 EFAVVLPDTDLEaaiaiAERIRQKINE-LPFVHELSREPLEVTISIGVAEGKPGE-DSIEELLKRADKALYKAKASGR 427

-1

137615

PRK09966

hypothetical protein; Provisional

false

true

false

407

5e-05

45.01

27.27

3,292,249,23,315,278,65,380,345,15

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 293 HDPLTGLPNRRRLEEDFRLLRGR------WALCRLDLVDLYEVNEAYGREAGDALLARTSRRLQALLPREGRLYRLEGGE 366
PRK09966    250 HDPLTGLANRAAFRSGINTLMNNsdarktSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEFGGLRHKAYRLGGDE 329

                        90       100       110
                ....*....|....*....|....*....|.
gi 46198730 367 FLALLPGGAKEAEA--FGQALGEALEAPLDL 395
PRK09966    330 FAMVLYDVQSESEVqqICSALTQIFNLPFDL 360

-1

130876

TIGR01817

nifA

Nif-specific regulatory protein

false

true

false

534

5e-04

41.62

15.36

3,193,71,28,222,99,30,252,130,23

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46198730 194 GQGPTGRALRSGRPQVLRSVEEDPRYAPwRERAQVFGFASSAAFPLRVEGRVWGSLNVY-APEEDAFDEEEVRLLEDLAR 272
TIGR01817    72 GEGAIGQIVATGNSLVVPDVAAEPLFLD-RLSLYDPGPVPFIGVPIKADSETIGVLAADrDFRSRERLEEEVRFLEMVAN 150


                ...
gi 46198730 273 LIG 275
TIGR01817   151 LIG 153

-1

active site	0	10	10	true	133472	cd01949	GGDEF
I-site	1	3	3	true	133472	cd01949	GGDEF