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Conserved domains on  [gi|30021736|ref|NP_833367|]
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Serine/threonine protein phosphatase [Bacillus cereus ATCC 14579]

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List of domain hits

Name Accession Description Interval E-value
PP2Cc super family cl00120
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
22-250 8.41e-12

Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.


The actual alignment was detected with superfamily member pfam13672:

Pssm-ID: 260203  Cd Length: 210  Bit Score: 61.56  E-value: 8.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736    22 CEDSYFCNKEKKIYG--VCDGATplvtfRDEKGHNGAYIASHLFASYFTALRENHSLQFAVAKA----NEALQSKMLEYE 95
Cdd:pfam13672  12 CQDAFAYRVLSDGWLiaVADGAG-----SAKYSDVGARLAVEAAVEALRELLDSGELPELEALVrqilNDILALVRQEAA 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736    96 VDTRKKEHLWCTCIAAVqIVGEKIEYAQLGDCMIVATFQNGTMQVLTKDtvegiskrakkkreedrkkglsvpeeyvfqD 175
Cdd:pfam13672  87 AQGLEPRDYATTLLLAV-ITPGGIVFFQIGDGAIVVRDRDGELQLLSEP------------------------------D 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736   176 VREQlkynrylANMPngYSVAngMKEAIHYLQHGELHTDEVSGIFICSDGLF-----HPDW--SLEQTVAYIRKNSINEY 248
Cdd:pfam13672 136 SGEY-------ANET--TFLT--SPDALEEFRIRRLTLEPGDALALMTDGLSdslvtEEPFfpFFAPLLETLEEEGASEQ 204

                  ..
gi 30021736   249 IA 250
Cdd:pfam13672 205 LA 206
 
Name Accession Description Interval E-value
PP2C_2 pfam13672
Protein phosphatase 2C; Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine ...
22-250 8.41e-12

Protein phosphatase 2C; Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.


Pssm-ID: 257978  Cd Length: 210  Bit Score: 61.56  E-value: 8.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736    22 CEDSYFCNKEKKIYG--VCDGATplvtfRDEKGHNGAYIASHLFASYFTALRENHSLQFAVAKA----NEALQSKMLEYE 95
Cdd:pfam13672  12 CQDAFAYRVLSDGWLiaVADGAG-----SAKYSDVGARLAVEAAVEALRELLDSGELPELEALVrqilNDILALVRQEAA 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736    96 VDTRKKEHLWCTCIAAVqIVGEKIEYAQLGDCMIVATFQNGTMQVLTKDtvegiskrakkkreedrkkglsvpeeyvfqD 175
Cdd:pfam13672  87 AQGLEPRDYATTLLLAV-ITPGGIVFFQIGDGAIVVRDRDGELQLLSEP------------------------------D 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736   176 VREQlkynrylANMPngYSVAngMKEAIHYLQHGELHTDEVSGIFICSDGLF-----HPDW--SLEQTVAYIRKNSINEY 248
Cdd:pfam13672 136 SGEY-------ANET--TFLT--SPDALEEFRIRRLTLEPGDALALMTDGLSdslvtEEPFfpFFAPLLETLEEEGASEQ 204

                  ..
gi 30021736   249 IA 250
Cdd:pfam13672 205 LA 206
PP2Cc cd00143
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
19-273 9.25e-10

Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.


Pssm-ID: 238083  Cd Length: 254  Bit Score: 56.57  E-value: 9.25e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736  19 KQECEDSYFCNKEKK-----IYGVCDGatplvtFRdekGHNGAYIASHLFASYFTALRENHSLQF------AVAKANEAL 87
Cdd:cd00143  12 RKTNEDAVVIKPNLNnedggLFGVFDG------HG---GHAAGEFASKLLVEELLEELEETLTLSeedieeALRKAFLRA 82
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736  88 QSKMLEYEVDTRKKEHLWCTCIAAVqIVGEKIEYAQLGDCMIVAtFQNGTMQVLTKD---TVEGISKRakkkreedrkkg 164
Cdd:cd00143  83 DEEILEEAQDEPDDARSGTTAVVAL-IRGNKLYVANVGDSRAVL-CRNGEAVQLTKDhkpVNEEERER------------ 148
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736 165 LSVPEEYVFQdvreqlkynrylANMPNGYSVAN--GMKEAIHYLQ-HGELHTDEVSG----IFICSDGLFhpDW-SLEQT 236
Cdd:cd00143 149 IEKAGGRVSN------------GRVPGVLAVTRalGDFDLKPGVSaEPDVTVVKLTEdddfLILASDGLW--DVlSNQEA 214
                       250       260       270       280
                ....*....|....*....|....*....|....*....|
gi 30021736 237 VAYIRKNSINEYI-AIIEEL--EAEKRIRPDDKTIIMIDF 273
Cdd:cd00143 215 VDIVRSELAKEDLqEAAQELvdLALRRGSHDNITVVVVRL 254
PTC1 COG0631
Serine/threonine protein phosphatase [Signal transduction mechanisms]
23-273 2.94e-08

Serine/threonine protein phosphatase [Signal transduction mechanisms]


Pssm-ID: 223704  Cd Length: 262  Bit Score: 52.36  E-value: 2.94e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736  23 EDSYFCNKEKKI-----YGVCDGATplvtfrdekGHNGAYIASHLFASYFTALRENHSLQFAVAKANEALQS--KMLEYE 95
Cdd:COG0631  24 EDAFLIKPNENGnllllFAVADGMG---------GHAAGEVASKLAVEALARLFDETNFNSLNESLEELLKEaiLKANEA 94
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736  96 VDTRKKEHLWC----TCIAAVQIVGEKIEYAQLGDCMIVaTFQNGTMQVLTKDTVegiskrakkkreedrkkglsvpeeY 171
Cdd:COG0631  95 IAEEGQLNEDVrgmgTTLVLLLIRGNKLYVANVGDSRAY-LLRDGELKQLTEDHS------------------------L 149
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736 172 VFQDVREQLKYNRYLANMPNGYSVAN--GMKEAIHY-LQHGELHTDEVsgIFICSDGLFhpDW-SLEQTVAYIRKNSINE 247
Cdd:COG0631 150 VNRLEQRGIITPEEARSHPRRNALTRalGDFDLLEPdITELELEPGDF--LLLCSDGLW--DVvSDDEIVDILKNSETPQ 225
                       250       260
                ....*....|....*....|....*...
gi 30021736 248 YIAiiEEL--EAEKRIRPDDKTIIMIDF 273
Cdd:COG0631 226 EAA--DKLieLALEGGGPDNITVVLVRL 251
PP2Cc smart00332
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
19-271 1.63e-06

Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.


Pssm-ID: 214625  Cd Length: 252  Bit Score: 46.98  E-value: 1.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736     19 KQECEDSYFCNKEK----KIYGVCDGatplvtfrdekgHNGAYIASHL---FASYFTALRENHSLQF-----AVAKANEA 86
Cdd:smart00332  20 RKPMEDAHVITPDLsdsgGFFGVFDG------------HGGSEAAKFLsknLPEILAEELIKEKDELedveeALRKAFLS 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736     87 LQSKMLEyevdtRKKEHLWCTCIAAVqIVGEKIEYAQLGDCMIVAtFQNGTMQVLTKD-TVEGISKRAkkkreEDRKKGL 165
Cdd:smart00332  88 TDEEILE-----ELEALSGSTAVVAL-ISGNKLYVANVGDSRAVL-CRNGKAVQLTEDhKPSNEDERA-----RIEAAGG 155
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736    166 SVPEEYVFQdvreqlkyNRYLANMPnGYSVANGMKEAIHYLQHGELhTDEVSGIFICSDGLFHPDwSLEQTVAYIRKNSI 245
Cdd:smart00332 156 FVINGRVNG--------VLALSRAI-GDFFLKPYVSAEPDVTVVEL-TEKDDFLILASDGLWDVL-SNQEVVDIVRKHLS 224
                          250       260
                   ....*....|....*....|....*...
gi 30021736    246 NEYIAIIEEL--EAEKRIRPDDKTIIMI 271
Cdd:smart00332 225 KDPKEAAKRLidLALARGSKDNITVVVV 252
 
Name Accession Description Interval E-value
PP2C_2 pfam13672
Protein phosphatase 2C; Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine ...
22-250 8.41e-12

Protein phosphatase 2C; Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.


Pssm-ID: 257978  Cd Length: 210  Bit Score: 61.56  E-value: 8.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736    22 CEDSYFCNKEKKIYG--VCDGATplvtfRDEKGHNGAYIASHLFASYFTALRENHSLQFAVAKA----NEALQSKMLEYE 95
Cdd:pfam13672  12 CQDAFAYRVLSDGWLiaVADGAG-----SAKYSDVGARLAVEAAVEALRELLDSGELPELEALVrqilNDILALVRQEAA 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736    96 VDTRKKEHLWCTCIAAVqIVGEKIEYAQLGDCMIVATFQNGTMQVLTKDtvegiskrakkkreedrkkglsvpeeyvfqD 175
Cdd:pfam13672  87 AQGLEPRDYATTLLLAV-ITPGGIVFFQIGDGAIVVRDRDGELQLLSEP------------------------------D 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736   176 VREQlkynrylANMPngYSVAngMKEAIHYLQHGELHTDEVSGIFICSDGLF-----HPDW--SLEQTVAYIRKNSINEY 248
Cdd:pfam13672 136 SGEY-------ANET--TFLT--SPDALEEFRIRRLTLEPGDALALMTDGLSdslvtEEPFfpFFAPLLETLEEEGASEQ 204

                  ..
gi 30021736   249 IA 250
Cdd:pfam13672 205 LA 206
PP2Cc cd00143
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
19-273 9.25e-10

Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.


Pssm-ID: 238083  Cd Length: 254  Bit Score: 56.57  E-value: 9.25e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736  19 KQECEDSYFCNKEKK-----IYGVCDGatplvtFRdekGHNGAYIASHLFASYFTALRENHSLQF------AVAKANEAL 87
Cdd:cd00143  12 RKTNEDAVVIKPNLNnedggLFGVFDG------HG---GHAAGEFASKLLVEELLEELEETLTLSeedieeALRKAFLRA 82
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736  88 QSKMLEYEVDTRKKEHLWCTCIAAVqIVGEKIEYAQLGDCMIVAtFQNGTMQVLTKD---TVEGISKRakkkreedrkkg 164
Cdd:cd00143  83 DEEILEEAQDEPDDARSGTTAVVAL-IRGNKLYVANVGDSRAVL-CRNGEAVQLTKDhkpVNEEERER------------ 148
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736 165 LSVPEEYVFQdvreqlkynrylANMPNGYSVAN--GMKEAIHYLQ-HGELHTDEVSG----IFICSDGLFhpDW-SLEQT 236
Cdd:cd00143 149 IEKAGGRVSN------------GRVPGVLAVTRalGDFDLKPGVSaEPDVTVVKLTEdddfLILASDGLW--DVlSNQEA 214
                       250       260       270       280
                ....*....|....*....|....*....|....*....|
gi 30021736 237 VAYIRKNSINEYI-AIIEEL--EAEKRIRPDDKTIIMIDF 273
Cdd:cd00143 215 VDIVRSELAKEDLqEAAQELvdLALRRGSHDNITVVVVRL 254
PTC1 COG0631
Serine/threonine protein phosphatase [Signal transduction mechanisms]
23-273 2.94e-08

Serine/threonine protein phosphatase [Signal transduction mechanisms]


Pssm-ID: 223704  Cd Length: 262  Bit Score: 52.36  E-value: 2.94e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736  23 EDSYFCNKEKKI-----YGVCDGATplvtfrdekGHNGAYIASHLFASYFTALRENHSLQFAVAKANEALQS--KMLEYE 95
Cdd:COG0631  24 EDAFLIKPNENGnllllFAVADGMG---------GHAAGEVASKLAVEALARLFDETNFNSLNESLEELLKEaiLKANEA 94
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736  96 VDTRKKEHLWC----TCIAAVQIVGEKIEYAQLGDCMIVaTFQNGTMQVLTKDTVegiskrakkkreedrkkglsvpeeY 171
Cdd:COG0631  95 IAEEGQLNEDVrgmgTTLVLLLIRGNKLYVANVGDSRAY-LLRDGELKQLTEDHS------------------------L 149
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736 172 VFQDVREQLKYNRYLANMPNGYSVAN--GMKEAIHY-LQHGELHTDEVsgIFICSDGLFhpDW-SLEQTVAYIRKNSINE 247
Cdd:COG0631 150 VNRLEQRGIITPEEARSHPRRNALTRalGDFDLLEPdITELELEPGDF--LLLCSDGLW--DVvSDDEIVDILKNSETPQ 225
                       250       260
                ....*....|....*....|....*...
gi 30021736 248 YIAiiEEL--EAEKRIRPDDKTIIMIDF 273
Cdd:COG0631 226 EAA--DKLieLALEGGGPDNITVVLVRL 251
PP2Cc smart00332
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and ...
19-271 1.63e-06

Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.


Pssm-ID: 214625  Cd Length: 252  Bit Score: 46.98  E-value: 1.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736     19 KQECEDSYFCNKEK----KIYGVCDGatplvtfrdekgHNGAYIASHL---FASYFTALRENHSLQF-----AVAKANEA 86
Cdd:smart00332  20 RKPMEDAHVITPDLsdsgGFFGVFDG------------HGGSEAAKFLsknLPEILAEELIKEKDELedveeALRKAFLS 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736     87 LQSKMLEyevdtRKKEHLWCTCIAAVqIVGEKIEYAQLGDCMIVAtFQNGTMQVLTKD-TVEGISKRAkkkreEDRKKGL 165
Cdd:smart00332  88 TDEEILE-----ELEALSGSTAVVAL-ISGNKLYVANVGDSRAVL-CRNGKAVQLTEDhKPSNEDERA-----RIEAAGG 155
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30021736    166 SVPEEYVFQdvreqlkyNRYLANMPnGYSVANGMKEAIHYLQHGELhTDEVSGIFICSDGLFHPDwSLEQTVAYIRKNSI 245
Cdd:smart00332 156 FVINGRVNG--------VLALSRAI-GDFFLKPYVSAEPDVTVVEL-TEKDDFLILASDGLWDVL-SNQEVVDIVRKHLS 224
                          250       260
                   ....*....|....*....|....*...
gi 30021736    246 NEYIAIIEEL--EAEKRIRPDDKTIIMI 271
Cdd:smart00332 225 KDPKEAAKRLidLALARGSKDNITVVVV 252
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.13
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2015), "CDD: NCBI's conserved domain database.", Nucleic Acids Res.43(D)222-6.
  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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