15-lipoxygenase, partial [Homo sapiens]
List of domain hits
Name | Accession | Description | Interval | E-value | ||
PLAT super family | cl00011 | PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. ... |
2-46 | 8.74e-16 | ||
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and polycystin, but also as a single domain or as repeats.The putative function of this domain is to facilitate access to sequestered membrane or micelle bound substrates. The actual alignment was detected with superfamily member cd01753: Pssm-ID: 412108 Cd Length: 113 Bit Score: 64.25 E-value: 8.74e-16
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Name | Accession | Description | Interval | E-value | ||
PLAT_LOX | cd01753 | PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they ... |
2-46 | 8.74e-16 | ||
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and plasma lipoproteins. Both types of enzymes are cytosolic but need this domain to access their sequestered membrane or micelle bound substrates. Pssm-ID: 238851 Cd Length: 113 Bit Score: 64.25 E-value: 8.74e-16
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LH2 | smart00308 | Lipoxygenase homology 2 (beta barrel) domain; |
4-46 | 9.03e-07 | ||
Lipoxygenase homology 2 (beta barrel) domain; Pssm-ID: 214608 [Multi-domain] Cd Length: 105 Bit Score: 41.09 E-value: 9.03e-07
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PLAT | pfam01477 | PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. ... |
4-35 | 6.91e-06 | ||
PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain binds to procolipase pfam01114, which mediates membrane association. So it appears possible that this domain mediates membrane attachment via other protein binding partners. The structure of this domain is known for many members of the family and is composed of a beta sandwich. Pssm-ID: 396180 Cd Length: 115 Bit Score: 38.95 E-value: 6.91e-06
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Name | Accession | Description | Interval | E-value | ||
PLAT_LOX | cd01753 | PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they ... |
2-46 | 8.74e-16 | ||
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and plasma lipoproteins. Both types of enzymes are cytosolic but need this domain to access their sequestered membrane or micelle bound substrates. Pssm-ID: 238851 Cd Length: 113 Bit Score: 64.25 E-value: 8.74e-16
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LH2 | smart00308 | Lipoxygenase homology 2 (beta barrel) domain; |
4-46 | 9.03e-07 | ||
Lipoxygenase homology 2 (beta barrel) domain; Pssm-ID: 214608 [Multi-domain] Cd Length: 105 Bit Score: 41.09 E-value: 9.03e-07
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PLAT | pfam01477 | PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. ... |
4-35 | 6.91e-06 | ||
PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain binds to procolipase pfam01114, which mediates membrane association. So it appears possible that this domain mediates membrane attachment via other protein binding partners. The structure of this domain is known for many members of the family and is composed of a beta sandwich. Pssm-ID: 396180 Cd Length: 115 Bit Score: 38.95 E-value: 6.91e-06
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PLAT | cd00113 | PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. ... |
2-31 | 1.24e-03 | ||
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and polycystin, but also as a single domain or as repeats.The putative function of this domain is to facilitate access to sequestered membrane or micelle bound substrates. Pssm-ID: 238061 Cd Length: 116 Bit Score: 33.08 E-value: 1.24e-03
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Blast search parameters | ||||
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