NCBI Conserved Domain Search

NewSearch

CDD Home

Conserved domains on [gi\|15806634\|ref\|NP_295352.1\|]
c-di-GMP phosphodiesterase A [Deinococcus radiodurans R1]

Graphical summary show options »	Show site features Horizontal zoom: ×	?



List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH

of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

30163

cd01948

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

true

false

true

240

7e-67

250.52

92.08

4,570,0,126,696,127,16,712,144,37,750,181,40

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 571 QALRSGIGNGELVLHYQPIVEVRSGKTVAVEALVRWQHPRLGLLSPDRFIGLAEDNGLIVPLGRWVLNTALRQLAAWREH 650
cd01948       1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQAG 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 651 WPELRVSVNMAPRQLQQPGSCQEIRDALRAYALPPDALELEITEQT-ICDEEALEPFLPLIRE-GLRLAIDDFGTGYSSL 728
cd01948      81 GPDLRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESAlIDDLEEALATLRRLRAlGVRIALDDFGTGYSSL 160

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15806634 729 SRLYRLPAQILKLDRSLIQDLsADNATDGPLVSALIAFAQRFGMQVTAEGIETAEQLHLLRQ 790
cd01948     161 SYLKRLPVDYLKIDRSFVRDI-ETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRE 221

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

133472

cd01949

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as domain of unknown function 1 (DUF1). It is widely present in bacteria and often links to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain has been suggested to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesiveness in bacteria.

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

true

false

true

157

1e-38

156.59

97.45

3,399,0,23,422,26,66,489,92,61

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 400 HDALTGLPNRLALHEALGQQVAA---DSAPFALLCLDLDHFKTVNHTLGQPAGDALLLYIGERVQAAVGEQGQTFRRGGN 476
cd01949       1 TDPLTGLPNRRAFEERLERLLARarrSGRPLALLLIDLDHFKQINDTYGHAAGDEVLKEVARRLRSSLRESDLVARLGGD 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15806634 477 EFVVLLPAVRAApDALTIAQTLLDTINEPLLLDGQALVVTASIGLALFPEDGRDSLTLQKNADLALHAAKQEGG 550
cd01949      81 EFAILLPGTDLE-EAEELAERLRKAIEEPFFIDGEEIRVTASIGIAEYPEDGEDLEELLRRADKALYQAKRSGR 153

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

128367

smart00052

EAL

Putative diguanylate phosphodiesterase

false

241

2e-68

255.99

91.70

4,570,1,129,699,131,13,712,145,42,755,187,35

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 571 QALRSGIGNGELVLHYQPIVEVRSGKTVAVEALVRWQHPRLGLLSPDRFIGLAEDNGLIVPLGRWVLNTALRQLAAWREH 650
smart00052    2 RELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQAQ 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 651 WPELRVSVNMAPRQLQQPGSCQEIRDALRAYALPPDALELEITEQTICD-EEALEPFLPLIRE-GLRLAIDDFGTGYSSL 728
smart00052   82 GPPLRISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDdDESAVATLQRLRElGVRIALDDFGTGYSSL 161

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15806634 729 SRLYRLPAQILKLDRSLIQDLSADNAtDGPLVSALIAFAQRFGMQVTAEGIETAEQLHLLRQ 790
smart00052  162 SYLKRLPVDLLKIDKSFVRDLQTDPE-DEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRS 222

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

32382

COG2200

Rtn

c-di-GMP phosphodiesterase class I (EAL domain) [Signal transduction mechanisms]

false

256

2e-61

232.52

87.89

5,565,0,85,651,85,45,696,131,16,712,148,42,755,190,35

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 566 RLELTQALRSGIGNGELVLHYQPIVEVRSGKTVAVEALVRWQHPRLGLLSPDRFIGLAEDNGLIVPLGRWVLNTALRQLA 645
COG2200       1 RLQLERDLRQALENGEFSLYYQPIVDLATGRIVGYEALLRWRHPDGGLISPGEFIPLAEETGLIVELGRWVLEEACRQLR 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 646 AWREHwPELRVSVNMAPRQLQQPGSCQEIRDALRAYALPPDALELEITEQT-ICDEEALEPFLPLIRE-GLRLAIDDFGT 723
COG2200      81 TWPRA-GPLRLAVNLSPVQLRSPGLVDLLLRLLARLGLPPHRLVLEITESAlIDDLDTALALLRQLRElGVRIALDDFGT 159

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15806634 724 GYSSLSRLYRLPAQILKLDRSLIQDLSADNAtDGPLVSALIAFAQRFGMQVTAEGIETAEQLHLLRQ 790
COG2200     160 GYSSLSYLKRLPPDILKIDRSFVRDLETDAR-DQAIVRAIVALAHKLGLTVVAEGVETEEQLDLLRE 225

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

109613

pfam00563

EAL

EAL domain

false

236

2e-52

202.65

93.64

5,570,1,81,651,85,24,676,109,36,712,146,37,751,183,39

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 571 QALRSGIGNGELVLHYQPIVEVRSGKTVAVEALVRWQHPRLGLLSPDRFIGLAEDNGLIVPLGRWVLNTALRQLAAWREH 650
pfam00563     2 QALREALENGEFSLYFQPIVDLRTGKVLGYEALLRWQHPDGGLIPPDEFLPLAERLGLIAELDRWVLEKALAQLAEWRGN 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 651 W---PELRVSVNMAPRQLQQPGSCQEIRdALRAYALPPDALELEITEQTICDEEALEPFLPLIRE-GLRLAIDDFGTGYS 726
pfam00563    82 AllpPDLPLSVNLSPASLLDPSFLEALL-ALKQGGLPPSRLVLEITESDLDEDLRLLEALARLRSlGFRLALDDFGTGYS 160

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15806634 727 SLSRLYRLPAQILKLDRSLIQDLsaDNATDGPLVSALIAFAQRFGMQVTAEGIETAEQLHLLRQ 790
pfam00563   161 SLSYLSRLPPDYIKIDRSFIKDL--SDPESRALLRALIALARELGIKVVAEGVETEEQLELLKE 222

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

128563

smart00267

GGDEF

diguanylate cyclase

false

163

6e-33

137.76

95.71

3,396,1,26,422,30,66,489,96,61

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 397 QLRHDALTGLPNRLALHEALGQQVAA---DSAPFALLCLDLDHFKTVNHTLGQPAGDALLLYIGERVQAAVGEQGQTFRR 473
smart00267    2 LAFRDPLTGLPNRRYFEEELEQELQRaqrQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRPGDLLARL 81

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15806634 474 GGNEFVVLLPAVRAApDALTIAQTLLDTINEPLLLDGQALVVTASIGLALFPEDGRDSLTLQKNADLALHAAKQEGG 550
smart00267   82 GGDEFALLLPETSLE-EAIALAERILQQLREPIIIHGIPLYLTISIGVAAYPNPGEDAEDLLKRADTALYQAKKAGR 157

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

32381

COG2199

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction...

false

181

2e-32

136.40

95.03

4,381,3,43,424,49,64,489,113,43,532,157,18

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 382 RRLKEEGRTQQRLAAQLRHDALTGLPNRLALHEALGQQVAADS---APFALLCLDLDHFKTVNHTLGQPAGDALLLYIGE 458
COG2199       4 RLLTRLRKAEERLERLALHDPLTGLPNRRAFEERLERALARARrhgEPLALLLLDLDHFKQINDTYGHAAGDEVLREVAR 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 459 RVQAAVGEQGQTFRRGGNEFVVLLPAVRAApDALTIAQTLLDTINEPLLLDGQALVVTASIGLALFPEDGRDSL-TLQKN 537
COG2199      84 RLRSNLREGDLVARLGGDEFAVLLPGTSLE-EAARLAERIRAALEEPFFLGGEELRVTVSIGVALYPEDGSDDAeLLLRR 162

                       170
                ....*....|...
gi 15806634 538 ADLALHAAKQEGG 550
COG2199     163 ADLALYRAKRAGR 175

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

110022

pfam00990

GGDEF

GGDEF domain

false

160

2e-32

136.22

97.50

3,399,2,20,419,25,67,486,94,64

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 400 HDALTGLPNRLALHEALGQQ---VAADSAPFALLCLDLDHFKTVNHTLGQPAGDALLLYIGERVQAAVGEQGQTFRRGGN 476
pfam00990     3 HDPLTGLPNRRYFEEELEQElqrAQRRQSPLALLLLDLDNFKRINDTYGHAVGDEVLQEVAQRLSSSLRRSDLVARLGGD 82

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15806634 477 EFVVLLPAVR--AAPDALTIAQTLLDTINEPLLLDGQALVVTASIGLALFPEDGRDSLTLQKNADLALHAAKQEGG 550
pfam00990    83 EFAILLPDTSleGAQELAERIRRLLAALKIPHTLSGLPLYVTISIGIAAYPNDGEDAEDLLKRADQALYQAKNQGR 158

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

129356

TIGR00254

GGDEF

diguanylate cyclase (GGDEF) domain

false

165

2e-25

113.20

93.33

5,399,3,21,420,27,68,489,95,14,503,110,5,508,116,41

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 400 HDALTGLPNRLALHEALGQQV---AADSAPFALLCLDLDHFKTVNHTLGQPAGDALLLYIGERVQAAVGEQGQTFRRGGN 476
TIGR00254     4 RDPLTGLYNRRYLEEMLDSELkraRRFQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRYGGE 83

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15806634 477 EFVVLLPAVRAApDALTIAQTLLDTIN-EPLLL-DGQALVVTASIGLALFPEDGRDSLTLQKNADLALHAAKQEG 549
TIGR00254    84 EFVVILPGTPLE-DALSKAERLRDAINsKPIEVaGSETLTVTVSIGVACYPGHGLTLEELLKRADEALYQAKKAG 157

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

138661

PRK11596

EAL domain-containing protein; Provisional

false

255

6e-04

41.62

76.86

11,584,32,8,593,40,18,611,60,7,618,68,12,636,80,17,653,99,13,669,112,16,686,128,10,699,138,52,753,190,4,757,195,33

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 585 HYQPIVEVrSGKTVAVEALVRWQHPRL--GLLSPDR-FIGLAEDNGLIVplgrwvLNTALRQLAAWREHWPE--LRVSVN 659
PRK11596     33 TFQPIYRT-CGRLMAVELLTVVTHPSNpsQRLSPDRyFAEITVSHRLDV------VKEQLDLLAQKADFFVRhgLLASVN 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 660 MAPRQLQqpgSCQEIRDALRAYALPPdALELEITEQTicdEEALEPFLPLIREGLRLAIDDFGTGYSSLSRLYRLPAQIL 739
PRK11596    106 IDGPTLI---ALRQQPKILRLIERLP-WLRFELVEHI---RLPKDSTFASMCEFGPLWLDDFGTGMANFSALSEVRYDYI 178

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 15806634 740 KLDRSLIQDLSAdnATDG-PLVSALIAFAQRFGMQVTAEGIETAEQLHLLRQ 790
PRK11596    179 KVARELFVMLRQ--SPEGrTLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQR 228

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

29151

cd00189

TPR

Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here

Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[...

true

100

5e-04

41.99

99.00

3,125,1,31,162,32,39,207,71,29

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 126 AWLGLGLAHLNERRMARGLQAYLEALKICESlnapelSLRVLTNLASAYAKLEQYDTAQPYLTEAHDTARQLGQPFdlmi 205
cd00189       2 ALLNLGNLYYKLGDYDEALEYYEKALELDPD------NADAYYNLAAAYYKLGKYEEALEDYEKALELDPDNAKAY---- 71

                        90       100       110
                ....*....|....*....|....*....|.
gi 15806634 206 tsLNLACVCQLSGGTGAALTLIEEALRHAKT 236
cd00189      72 --YNLGLAYYKLGKYEEALEAYEKALELDPN 100

cl02429

141413

TPR

Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[...

137662

PRK10060

RNase II stability modulator; Provisional

false

true

false

663

6e-79

290.86

61.24

12,385,224,36,421,261,32,457,293,8,465,304,8,473,313,10,483,324,9,494,333,55,549,389,44,594,433,110,706,543,6,712,553,45,758,598,32

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 386 EEGRTQQRLAAQLRHDALTGLPNRLALHEALGQQVA-ADSAPFALLCLDLDHFKTVNHTLGQPAGDALLlyigERVQAAV 464
PRK10060    225 EERRAQERLRILANTDSITGLPNRNAIQELIDHAIAqADNNQVGIVYLDLDNFKKVNDAYGHMFGDQLL----QDVSLAI 300

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 465 G---EQGQTFRR-GGNEFVVLLP-AVRAAPDALtiAQTLLDTINEPLLLDGQALVVTASIGLALFPEDGRDSLTLQKNAD 539
PRK10060    301 LsclEEDQTLARlGGDEFLVLAShTSQAALEAM--ASRILTRLRLPFRIGLIEVYTGCSIGIALSPEHGDDSESLIRSAD 378

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 540 LALHAAKQEG-GQAQRYRNALSQAANERLELTQALRSGIGNGELVLHYQPIVEVRsGKTVAVEALVRWQHPRLGLLSPDR 618
PRK10060    379 TAMYTAKEGGrGQFCVFSPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWR-GEVRSLEALVRWQSPERGLIPPLE 457

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 619 FIGLAEDNGLIVPLGRWVLNTALRQLAAWREHWPELRVSVNMAPRQLQQPGSCQEIRDALRAYALPPDALELEITEQTIC 698
PRK10060    458 FISYAEESGLIVPLGRWVILDVVRQAAKWRDKGINLRVAVNVSARQLADQTIFTALKQVLQELNFEYCPIDVELTESCLI 537

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 699 DEEALEpfLPLIRE----GLRLAIDDFGTGYSSLSRLYRLPAQILKLDRSLIQDLSADNATDGpLVSALIAFAQRFGMQV 774
PRK10060    538 ENEELA--LSVIQQfsqlGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQS-LVRAIVAVAQALNLQV 614

                       410
                ....*....|....*.
gi 15806634 775 TAEGIETAEQLHLLRQ 790
PRK10060    615 IAEGVETAKEDAFLTK 630

-1

34606

COG5001

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF...

false

true

false

663

6e-73

270.74

62.29

8,376,208,22,400,230,22,422,255,127,549,383,99,651,482,45,696,528,16,712,545,38,751,583,38

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 377 TLAEKRRLKEEGRTQQRLAAQLrhDALTGLPNRLALHEALGQQVAA---DSAPFALLCLDLDHFKTVNHTLGQPAGDALL 453
COG5001     209 TLTQRAEETRRLSDENDRLANL--DSLTGLPNRRRFFAELDARLAAarqSGRRLVLGVIDLDGFKPVNDAFGHATGDRLL 286

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 454 LYIGERVQAAVGEQGQTFRRGGNEFVVLLPAVRAAPDALTIAQTLLDTINEPLLLDGQALVVTASIGLALFPEDGRDSLT 533
COG5001     287 IEVGRRLKAFDGAPILAARLGGDEFALIIPALEDDALRVAGARALCESLQAPYDLRGVRVQVGASIGIAPFPSGADTSEQ 366

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 534 LQKNADLALHAAKQEG-GQAQRYRNALSQAANERLELTQALRSGIGNGELVLHYQPIVEVRSGKTVAVEALVRWQHPRLG 612
COG5001     367 LFERADYALYHAKQNGkGAAVLFDARHEAAIRDMAVVEQALRSADLEQELSVHFQPIVDIVSGKTIALEALARWHSPEIG 446

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 613 LLSPDRFIGLAEDNGLIVPLGRWVLNTALRQLAAWRehwPELRVSVNMAPRQLQQPGSCQEIRDALRAYALPPDALELEI 692
COG5001     447 PVPPDVFIGIAERSGQIVELTRLLLAKALREARAWP---MDVRVSINLSARDLASMENVRRLLAIVSESCIAPHRLDFEI 523

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 693 TEQT-ICDEEALEPFLPLIRE-GLRLAIDDFGTGYSSLSRLYRLPAQILKLDRSLIQDLSaDNATDGPLVSALIAFAQRF 770
COG5001     524 TETAiVCDFDQARDALAALHElGVRTALDDFGTGYSSLSHLRALPLDKIKIDRSFVSDLE-ENPTSEDIVRTVLQLGRNL 602

                       410
                ....*....|....*....
gi 15806634 771 GMQVTAEGIETAEQLHLLR 789
COG5001     603 RMECVVEGVETEAQRDRVA 621

-1

138538

PRK11359

cAMP phosphodiesterase; Provisional

false

true

false

799

5e-70

260.93

50.56

9,385,363,41,427,404,61,489,465,34,525,499,27,552,527,97,649,627,4,655,631,43,698,676,59,758,735,32

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 386 EEGRTQQRLAAQLRHDALTGLPNRLALHEALGQQVAADSAPfALLCLDLDHFKTVNHTLGQPAGDALLLYIGERVQAAVG 465
PRK11359    364 EQEKSRQHIEQLIQFDPMTGLPNRNNLHNYLDDLVDKAVSP-VVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLK 442

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 466 EQGQTFRRGGNEFVVLLPAVRAApDALTIAQTLLDTINEPLLLDGQALVVTASIGLALfpEDGRDSLTLQKNADLALHAA 545
PRK11359    443 PDQYLCRIEGTQFVLVSLENDVS-NITQIADELRNVVSKPIMIDDKPFPLTLSIGISY--DVGKNRDYLLSTAHNAMDYI 519

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 546 KQEGGQA-QRYRNALSQAANERLELTQALRSGIGNGELVLHYQPIVEVRSGKTVAVEALVRWQHPRLGLLSPDRFIGLAE 624
PRK11359    520 RKNGGNGwQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAE 599

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 625 DNGLIVPLGRWVLNTALRQLAAWRE---HWPElrVSVNMAPRQLQQPGSCQEIRDALRAYALPPDALELEITEQTIC--D 699
PRK11359    600 EIGEIENIGRWVIAEACRQLAEWRSqniHIPA--LSVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMehD 677

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 700 EEALEPFLPLIREGLRLAIDDFGTGYSSLSRLYRLPAQILKLDRSLIQDLSADNATDGpLVSALIAFAQRFGMQVTAEGI 779
PRK11359    678 TEIFKRIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILA-LLEAITSIGQSLNLTVVAEGV 756

                       410
                ....*....|.
gi 15806634 780 ETAEQLHLLRQ 790
PRK11359    757 ETKEQFEMLRK 767

-1

139666

PRK13561

putative phosphodiesterase; Provisional

false

true

false

651

6e-58

220.79

62.83

8,388,214,11,399,232,10,410,242,114,525,356,24,549,381,150,699,533,34,733,570,21,758,591,32

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 389 RTQQRLAAQLR-------HDALTGLPNRlALHEALGQQVAADSAPFALLCLDLDHFKTVNHTLGQPAGDALLLYIGERVQ 461
PRK13561    215 LNQQLLQRHYEeqnenamRFPVSDLPNK-ALLMALLEQVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLK 293

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 462 AAVGEQGQTFRRGGNEFVVLLPAVRAAPDALTIAQTLLDTINEPLLLDGQALVVTASIGLALFpEDGRDSLTLQKNADLA 541
PRK13561    294 SVLSPRMVLAQISGYDFAIIANGVKEPWHAITLGQQVLTIINERLPIQRIQLRPSCSIGIAMF-YGDLTAEQLYSRAVSA 372

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 542 LHAAKQEG-GQAQRYRNALSQAANERLELTQALRSGIGNGELVLHYQPIVEVRSGKTVAVEALVRWQHPRLGLLSPDRFI 620
PRK13561    373 AFTARRKGkNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMRSGKLVSAEALLRMQQPDGSWDLPDGLI 452

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 621 GLAEDNGLIVPLGRWVLNTALRQLAAWREHWPELRVSVNMAPRQLQQPGSCQEIRDALRAYALPPDALELEITEQTICD- 699
PRK13561    453 DRIESCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDd 532

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 700 -EEALEPFLPLIREGLRLAIDDFGTGYSSLSRLYR---LPAQILKLDRSLIQDLSADNAtdgpLVSALIAFAQRFGMQVT 775
PRK13561    533 pHAAVAILRPLRNAGVRIALDDFGMGYAGLRQLQHmksLPIDVLKIDKMFVDGLPEDSS----MVAAIIMLAQSLNLQMI 608

                       410
                ....*....|....*
gi 15806634 776 AEGIETAEQLHLLRQ 790
PRK13561    609 AEGVETEAQRDWLAK 623

-1

34551

COG4943

Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]

Predicted signal transduction protein containing sensor and EAL domains [Signal...

false

true

false

524

2e-49

192.87

43.32

3,563,263,149,712,413,44,757,457,33

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 564 NERLELTQALRSGIGNGELVLHYQPIVEVRSGKTVAVEALVRWQHPRLGLLSPDRFIGLAEDNGLIVPLGRWVLNTALRQ 643
COG4943     264 RRYLSPRRRLQRAIERRELCVHYQPIVDLATGKCVGAEALARWPQEDGTVVSPDVFIPLAEESGMIEQITDYVIRNVFRD 343

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 644 LAAWREHWPELRVSVNMAPRQLQQPGSCQEIRDALRAYALPPDALELEITEQTICDEEALEPFLPLIRE-GLRLAIDDFG 722
COG4943     344 LGDLLRQHRDLHVSINLSASDLASPRLIDRLNRKLAQYQVRPQQIALELTERTFADPKKMTPIILRLREaGHEIYIDDFG 423

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15806634 723 TGYSSLSRLYRLPAQILKLDRSLIQDLSADNATDgPLVSALIAFAQRFGMQVTAEGIETAEQLHLLRQ 790
COG4943     424 TGYSNLHYLQSLPVDALKIDKSFVDTLGTDSASH-LIAPHIIEMAKSLGLKIVAEGVETEEQVDWLRK 490

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

5e-45

177.97

36.83

13,386,675,7,393,683,25,418,710,13,431,724,54,486,778,18,504,797,45,549,843,23,572,868,31,603,900,36,640,936,60,700,997,12,712,1010,37,750,1047,39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634  387 EGRTQQR-LAAQLRHDALTGLPNRLALHEALGQ--QVAADSAPFALLC-LDLDHFKTVNHTLGQPAGDALLLYIGERVQA 462
PRK09776     676 ESRAMLRqLSYSASHDALTGLANRASFEKQLREalQTVNSTHQRHALVfIDLDRFKAVNDSAGHAAGDALLRELASLMLS 755

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634  463 AVGEQGQTFRRGGNEFVVLLPAVrAAPDALTIAQTLLDTINE-PLLLDGQALVVTASIGLALFPEDGRDSLTLQKNADLA 541
PRK09776     756 MLRSSDVLARLGGDEFGLLLPDC-NVESARFIATRIISAINDyRFPWEGRVYRVGASAGITAIDDNNHQASEVMSQADIA 834

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634  542 LHAAKQEG-GQAQRYRNALSQAANERLELTQA--LRSGIGNGELVLHYQPIVEVRSGKTVAVEAL-VRWQHPRLGLLSPD 617
PRK09776     835 CYAAKNAGrGRVTVYEPQQAAAHSERRELSLAeqWRSMLEENQLMLQAQEIASPRIPEARNLWLIsLRLWDCEGEIIDEG 914

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634  618 RFIGLAEDNGLIVPLGRWVLNTaLRQLAAWREHWPELRVSVNMAPRQLQQPGSCQEIRDALRAYALPPDALELEITEQTI 697
PRK09776     915 AFRPAAEDPALMHALDRWVIHE-LFQQGARAVASKGLSIAIPLSVASLSSATLLPFLLEQLENSPLPPRLLHLEITETAL 993

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634  698 CDE-EALEPFLPLIRE-GLRLAIDDFGTGYSSLSRLYRLPAQILKLDRSLIQDLsADNATDGPLVSALIAFAQRFGMQVT 775
PRK09776     994 LNHaEAASRLVQKLRLaGCRVVLDDFGRGLSSFNYLKAFMADYLKIDGELCANL-QGNLMDEMLVSIINGIAQRLGMKTI 1072

                        410
                 ....*....|....
gi 15806634  776 AEGIETAEQLHLLR 789
PRK09776    1073 AGPVELPLTLDTLS 1086

-1

138768

PRK11829

biofilm formation regulator HmsP; Provisional

false

true

false

728

1e-43

173.35

57.14

9,383,278,12,395,296,6,401,303,25,426,330,123,549,454,151,702,605,10,712,619,15,727,637,27,758,664,30

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 384 LKEEGRTQQRLA------AQLRHD-ALTGLPNRLALHEALGQQVAADSAP--FALLCLDLDHFKTVNHTLGQPAGDALLL 454
PRK11829    279 VRNYNRNQQLLAdayadmGRISHRfPVTELPNRSLFISLLEKEIASSTRTdhFHLLVIGIETLQEVSGAMSEAQHQQLLL 358

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 455 YIGERVQAAVGEQGQTFRRGGNEFVVLLPAVRAAPDALTIAQTLLDTINEPLLLDGQALVVTASIGLALFPEDGRDSLTL 534
PRK11829    359 TIVQRIEQCIDDSDLLAQLSKTEFAVLARGTRRSFPAMQLARRIMSQVTQPLFFDEITLRPSASIGITRYQAQQDTAESM 438

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 535 QKNADLALHAAKQEG-GQAQRYRNALSQAANERLELTQALRSGIGNGELVLHYQPIVEVRSGKTVAVEALVRWQHPRLGL 613
PRK11829    439 MRNASTAMMAAHHEGrNQIMVFEPHLIEKTHKRLTQENDLLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWCQPDGSY 518

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 614 LSPDRFIGLAEDNGLIVPLGRWVLNTALRQLAAWREHWPELRVSVNMAPRQLQQPGSCQEIRDALRAYALPPDALELEIT 693
PRK11829    519 VLPSGFVHFAEEEGMMVPLGNWVLEEACRILADWKARGVSLPLSVNISGLQVQNKQFLPHLKTLISHYHIDPQQLLLEIT 598

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 694 EQTICDEeaLEPFLPLIRE----GLRLAIDDFGTGYSS---LSRLYRLPAQILKLDRSLIQDLSADNAtdgpLVSALIAF 766
PRK11829    599 ETAQIQD--LDEALRLLRElqglGLLIALDDFGIGYSSlryLNHLKSLPIHMIKLDKSFVKNLPEDDA----IARIISCV 672

                       410       420
                ....*....|....*....|..
gi 15806634 767 AQRFGMQVTAEGIETAEQLHLL 788
PRK11829    673 SDVLKVRVMAEGVETEEQRQWL 694

-1

137979

PRK10551

hypothetical protein; Provisional

false

true

false

518

3e-38

155.60

41.89

7,574,269,79,653,349,23,677,372,3,681,375,8,689,385,11,700,397,55,756,452,34

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 575 SGIGNGELVLHYQPIVEVRSGKTVAVEALVRWQHPRLGLLSPDRFIGLAEDNGLIVPLGRWVLNTALRQLAAWREHWPE- 653
PRK10551    270 TAIKREQFYVVYQPVVDTQTLRVTGLEVLLRWRHPTAGEIPPDAFINYAEAQKLIVPLTQHLFELIARDAAELQKVLPVg 349

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 654 LRVSVNMAPRQLQQPGSCQEIRDaLRAyALPPDALE--LEITEQTICDE-EALEPFLPLIREGLRLAIDDFGTGYSSLSR 730
PRK10551    350 AKLGINIAPAHLHSDSFKADVQR-LLA-SLPADHFQivLEITERDMLQEeEALKLFAWLHSQGIEIAIDDFGTGHSALIY 427

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 731 LYRLPAQILKLDRSLIQDLSADNATdGPLVSALIAFAQRFGMQVTAEGIETAEQLHLLRQ 790
PRK10551    428 LERFTLDYLKIDRGFINAIGTETVT-SPVLDAVLTLAKRLNMLTVAEGVETPEQARWLRE 486

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

2e-19

93.06

42.30

5,371,242,18,389,261,25,414,289,70,485,359,19,504,381,45

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 372 RLRSETLAEKRRLKEEGR-TQQRLAAQLRHDALTGLPNRLALHE---ALGQQVAADSAPFALLCLDLDHFKTVNHTLGQP 447
COG3706     243 RARLRRQLRRKRYERQLReSLERLQELALVDGLTGLFNRRYFDEhlaDLWKRALREGRPLSLLMLDIDDFKEINDTYGHD 322

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 448 AGDALLLYIGERVQAAVGEQGQTFRRGGNEFVVLLPAvRAAPDALTIAQTLLDTINE---PLLLDGQALVVTASIGLALF 524
COG3706     323 VGDEVLRQVARRLRQTVRGLDLVARYGGEEFAVVLPD-TDLEAAIAIAERIRQKINElpfVHELSREPLEVTISIGVAEG 401

                       170       180
                ....*....|....*....|....*
gi 15806634 525 PEDGRDSLTLQKNADLALHAAKQEG 549
COG3706     402 KPGEDSIEELLKRADKALYKAKASG 426

-1

137400

PRK09581

pleD

response regulator PleD; Reviewed

false

true

false

457

1e-17

87.28

42.45

10,358,262,10,380,272,3,388,275,12,400,294,9,409,305,4,413,310,75,489,385,13,502,399,10,512,411,37,555,448,8

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 359 EQLAAVNLQLeaerlrsetlaeKRRlkeegRTQQRLAAQLRH-------DALTGLPNR--LALH-EALGQQVAADSAPFA 428
PRK09581    263 ELLARVRTQI------------RRK-----RYQDALRQNLEQsiemavtDGLTGLHNRryFDMHlKQLIERANERGKPLS 325

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 429 LLCLDLDHFKTVNHTLGQPAGDALLLYIGERVQAAVGEQGQTFRRGGNEFVVLLPAVRAApDALTIAQTLLDTI-NEPLL 507
PRK09581    326 LMMLDIDHFKQVNDTYGHDAGDEVLREFAKRLRKNIRGTDLIARYGGEEFVVVMPDTDIE-VAIAVAERIRRKIaEEPFA 404

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 15806634 508 LDGQA--LVVTASIGLALFPEDGRDSLTLQKNADLALHAAKQEGgqaqryRNALSQAA 563
PRK09581    405 ISDGKerLNVTVSIGVAELRPSGESIEALIKRADKALYEAKNTG------RNRVVALA 456

-1

138376

PRK11059

regulatory protein CsrD; Provisional

false

true

false

642

1e-17

86.86

65.42

19,371,204,5,377,209,5,384,214,29,413,246,58,471,306,13,485,319,14,499,336,15,517,351,9,527,360,25,552,386,13,565,404,9,578,413,13,592,426,58,652,484,32,684,517,16,700,534,12,712,547,35,747,584,8,758,592,32

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 372 RLRSEtLAEKRrlKEEGRTQQRLAAQLRHDALTGLPNRLALH---EALGQQVAADSAPFALLCLDLDHFKTVNHTLGQPA 448
PRK11059    205 HLLEE-LQDAR--KERSRFDTFIRSNAFLDAKTGLGNRLFFDnqlDTLLEDQEKVGAHGVVMLIRLPDFDLLQEELGESQ 281

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 449 GDALLLYIGERVQAAVGEQGQTF--RRGGNEFVVLLPAvRAAPDALTIAQTLL---DTINEPLLLDGQALVvtaSIGLAL 523
PRK11059    282 VDELLFELINLLSTFVQRYPGALlaRYSRSDFAVLLPH-RSLKEADSLASQLLkavDSLPPPKMLDRDDFL---HIGIAA 357

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 524 FPEdGRDSLTLQKNADLALHAAKQEGGQA-QRYRNALSQAANE-----RLELTQALRsgigNGELVLHYQPIVEvRSGKT 597
PRK11059    358 YRS-GQSTEQVMEEAEMALRSAQLQGGNSwFMYDKAQDPEKGRgsvrwRTLLEQALV----RGGPRLYQQPVVT-RDGQV 431

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 598 VAVEALVRWQHPRLGLLSPDRFIGLAEDNGLIVPLGRWVLNTALRQLAAWREHwpELRVSVNMAPRQLQQPGSCQEIRDA 677
PRK11059    432 HHRELMCRIRDGQGNEVRAAEFMPMVLQCGLSEQYDRQVIERVLPLLSYWPEE--SQNLSINLSVDSLLSRAFQRWLRDT 509

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 678 LRAYALP-PDALELEITEQTICDE-EALEPFLPLIRE-GLRLAIDDFGTGYSSLSRLYRLPAQILKLDRSLIQ--DLSAD 752
PRK11059    510 LLQCERSqRKRLIFELAEADVVQHiDRLRPVLRMLRGlGCRLAVDQAGLTVVSTSYIKELNVELIKLHPSLVRniHQRTE 589

                       410       420       430
                ....*....|....*....|....*....|....*...
gi 15806634 753 NATdgpLVSALIAFAQRFGMQVTAEGIETAEQLHLLRQ 790
PRK11059    590 NQL---FVRSLVGACAGTETQVFAEGVESREEWQTLQI 624

-1

137615

PRK09966

hypothetical protein; Provisional

false

true

false

407

5e-16

81.60

41.77

5,379,230,19,399,249,26,425,277,81,506,359,22,529,381,19

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 380 EKRRLKEEGRTQQRLAAQLrHDALTGLPNRLALHEALGQQVAADSA--PFALLCLDLDHFKTVNHTLGQPAGDALLLYIG 457
PRK09966    231 EEWQLRLQAKNAQLLRTAL-HDPLTGLANRAAFRSGINTLMNNSDArkTSALLFLDGDNFKYINDTWGHATGDRVLIEIA 309

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 458 ERVQAAVGEQGQTFRRGGNEFVVLLPAVRAAPDALTIAQTLLDTINEPL-LLDGQALVVTASIGLALFPEDGrDSLTLQK 536
PRK09966    310 KRLAEFGGLRHKAYRLGGDEFAMVLYDVQSESEVQQICSALTQIFNLPFdLHNGHQTTMTLSIGYAMTIEHA-SAEKLQE 388

                       170
                ....*....|..
gi 15806634 537 NADLALHAAKQE 548
PRK09966    389 LADHNMYQAKHQ 400

-1

137576

PRK09894

hypothetical protein; Provisional

false

true

false

293

9e-15

77.44

50.85

5,400,132,19,419,152,103,522,256,3,525,260,9,537,269,12

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 401 DALTGLPNRLALHEALGQQ-VAADSAPFALLCLDLDHFKTVNHTLGQPAGDALLLYIGERVQAAVGEQGQTFRRGGNEFV 479
PRK09894    133 DVLTGLPGRRVLDESFDHQlRNREPLNLYLALLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRPYETVYRYGGEEFI 212

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15806634 480 VLLPAVRAAPDALTIAQTLLDTINEPLLLDGQALVVTASIGLA-LFP-EDGRDSLTLqknADLALHAAKQEG 549
PRK09894    213 IILKAATDEEACRAGERIRQLIANQAITHSEGRINITATFGVTrAFPeEPLDEVIGR---ADRAMYEGKQAG 281

-1

137770

PRK10245

adrA

diguanylate cyclase AdrA; Provisional

false

true

false

371

1e-07

53.75

44.74

7,382,197,7,392,204,30,422,237,63,486,300,36,522,337,6,528,345,4,535,349,14

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 383 RLKEEGRtqqRLAAQLRHDALTGLPNRLALHEALGQQVAA---DSAPFALLCLDLDHFKTVNHTLGQPAGDALLLYIGER 459
PRK10245    198 KLAEHKR---RLQVMSTRDGMTGVYNRRHWETMLRNEFDNcrrHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQ 274

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 460 VQAAVGEQGQTFRRGGNEFVVLLPAVrAAPDALTIAQTLLDTINEPLLLDGQALVVTASIGLA-LFPEDG--RDSLtlqK 536
PRK10245    275 LQITLRGSDVIGRFGGDEFAVIMSGT-PAESAITAMLRVHEGLNTLRLPNAPQVTLRISVGVApLNPQMShyREWL---K 350

                       170
                ....*....|...
gi 15806634 537 NADLALHAAKQEG 549
PRK10245    351 SADLALYKAKKAG 363

-1

137202

PRK09303

adaptive-response sensory kinase; Validated

true

false

378

8e-04

41.10

25.40

2,297,106,41,344,147,55

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15806634 298 GRPAEARPALEAGLRAAQDLRLNDAEGRARRCYAQLLEDQDdyqgalAQVRALAQLEHDLREQLAAVNLQLEAERLRSET 377
PRK09303    107 GLGLSLRPSESDVGRTQELLQLSDELFVLRQENETLLEQLK------FKDRLLAMLAHDLRTPLTAASLAVETLELGQID 180

                        90       100
                ....*....|....*....|..
gi 15806634 378 LAEKRRLKEEGRTQQRLAAQLR 399
PRK09303    181 PSEELSPALIEQLQDQARRQLE 202

-1

active site	0	10	10	true	133472	cd01949	GGDEF
I-site	1	3	3	true	133472	cd01949	GGDEF
TPR motif	0	12	12	true	29151	cd00189	TPR
binding surface	1	17	18	true	29151	cd00189	TPR