NCBI Conserved Domain Search

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Conserved domains on [gi\|15805493\|ref\|NP_294189.1\|]
sensory box/GGDEF family protein [Deinococcus radiodurans R1]

Graphical summary show options »	Show site features Horizontal zoom: ×	?



List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

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of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

30163

cd01948

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

true

false

true

240

1e-81

299.44

100.00

2,538,0,79,620,79,161

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 539 HELRRALAADELRVRYQPVLDLDRGRIEGFEALVRWQHPERGLLGPDDFTPIAEESGLLPDIDRWVLARACRELVQWQRl 618
cd01948       1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQA- 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 619 ypHDPPLHLSVNFCSQHLAAPDVHERVKELLQRTGFDPGRLNLEITESSLLSQTGDVQRNMERLRQLGVRLHLDDFGTGY 698
cd01948      80 --GGPDLRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGY 157

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 699 SSLSYLQLYPIDVLKIDRSFVQGMLDNDSNAELVRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFSPALD 778
cd01948     158 SSLSYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLP 237


                ...
gi 15805493 779 VHA 781
cd01948     238 AEE 240

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

133472

cd01949

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as domain of unknown function 1 (DUF1). It is widely present in bacteria and often links to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain has been suggested to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesiveness in bacteria.

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

true

false

true

157

7e-47

184.33

100.00

4,352,0,30,383,30,59,443,89,24,477,113,44

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 353 HDSLTGLPNRALFSDRLSQAIARSKLPGGPqYAVLFLDVDRFKGINDTLGHPTGDAMLVEMARRLRACLRATDTVARLGG 432
cd01949       1 TDPLTGLPNRRAFEERLERLLARARRSGRP-LALLLIDLDHFKQINDTYGHAAGDEVLKEVARRLRSSLRESDLVARLGG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 433 DEFTILLEPLqSTEQAAQVAARIQDALRRPMQMPAagpgglpggwHQVTMSASLGIVHSQPDYDSAMAVLRDADIAMYRA 512
cd01949      80 DEFAILLPGT-DLEEAEELAERLRKAIEEPFFIDG----------EEIRVTASIGIAEYPEDGEDLEELLRRADKALYQA 148


                ....*....
gi 15805493 513 KDGGRAKYR 521
cd01949     149 KRSGRNRVV 157

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

128367

smart00052

EAL

Putative diguanylate phosphodiesterase

false

241

5e-81

297.59

98.34

2,537,0,80,620,80,157

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 538 EHELRRALAADELRVRYQPVLDLDRGRIEGFEALVRWQHPERGLLGPDDFTPIAEESGLLPDIDRWVLARACRELVQWQR 617
smart00052    1 ERELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQA 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 618 lypHDPPLHLSVNFCSQHLAAPDVHERVKELLQRTGFDPGRLNLEITESSLLSQTGDVQRNMERLRQLGVRLHLDDFGTG 697
smart00052   81 ---QGPPLRISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTG 157

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 698 YSSLSYLQLYPIDVLKIDRSFVQGMLDNDSNAELVRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFSPAL 777
smart00052  158 YSSLSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPL 237

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

32382

COG2200

Rtn

c-di-GMP phosphodiesterase class I (EAL domain) [Signal transduction mechanisms]

false

256

2e-77

286.07

99.61

2,534,1,81,619,82,174

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 535 NRMEHELRRALAADELRVRYQPVLDLDRGRIEGFEALVRWQHPERGLLGPDDFTPIAEESGLLPDIDRWVLARACRELVQ 614
COG2200       2 LQLERDLRQALENGEFSLYYQPIVDLATGRIVGYEALLRWRHPDGGLISPGEFIPLAEETGLIVELGRWVLEEACRQLRT 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 615 WqrlyPHDPPLHLSVNFCSQHLAAPDVHERVKELLQRTGFDPGRLNLEITESSLLSQTGDVQRNMERLRQLGVRLHLDDF 694
COG2200      82 W----PRAGPLRLAVNLSPVQLRSPGLVDLLLRLLARLGLPPHRLVLEITESALIDDLDTALALLRQLRELGVRIALDDF 157

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 695 GTGYSSLSYLQLYPIDVLKIDRSFVQGMLDNDSNAELVRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFS 774
COG2200     158 GTGYSSLSYLKRLPPDILKIDRSFVRDLETDARDQAIVRAIVALAHKLGLTVVAEGVETEEQLDLLRELGCDYLQGYLFS 237

                       250
                ....*....|....*....
gi 15805493 775 PALDVHAARTLVAEGQHHR 793
COG2200     238 RPLPADALDALLSSSQSRV 256

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

109613

pfam00563

EAL

EAL domain

false

236

5e-68

254.65

100.00

4,537,0,110,648,110,24,673,134,49,723,183,53

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 538 EHELRRALAADELRVRYQPVLDLDRGRIEGFEALVRWQHPERGLLGPDDFTPIAEESGLLPDIDRWVLARACRELVQWQR 617
pfam00563     1 EQALREALENGEFSLYFQPIVDLRTGKVLGYEALLRWQHPDGGLIPPDEFLPLAERLGLIAELDRWVLEKALAQLAEWRG 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 618 LYPHDPPLHLSVNFCSQHLAAPDVHERVKElLQRTGFDPGRLNLEITESSLLSQTgDVQRNMERLRQLGVRLHLDDFGTG 697
pfam00563    81 NALLPPDLPLSVNLSPASLLDPSFLEALLA-LKQGGLPPSRLVLEITESDLDEDL-RLLEALARLRSLGFRLALDDFGTG 158

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15805493 698 YSSLSYLQLYPIDVLKIDRSFVQGMlDNDSNAELVRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFSPA 776
pfam00563   159 YSSLSYLSRLPPDYIKIDRSFIKDL-SDPESRALLRALIALARELGIKVVAEGVETEEQLELLKELGIDYVQGYLFSKP 236

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

128563

smart00267

GGDEF

diguanylate cyclase

false

163

1e-41

166.65

100.00

4,348,0,34,383,34,56,440,90,27,477,117,46

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 349 HDALHDSLTGLPNRALFSDRLSQAIARSKLPGGPqYAVLFLDVDRFKGINDTLGHPTGDAMLVEMARRLRACLRATDTVA 428
smart00267    1 RLAFRDPLTGLPNRRYFEEELEQELQRAQRQGSP-FALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRPGDLLA 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 429 RLGGDEFTILLePLQSTEQAAQVAARIQDALRRPMQMPAagpgglpggwHQVTMSASLGIVHSQPDYDSAMAVLRDADIA 508
smart00267   80 RLGGDEFALLL-PETSLEEAIALAERILQQLREPIIIHG----------IPLYLTISIGVAAYPNPGEDAEDLLKRADTA 148

                       170
                ....*....|....*
gi 15805493 509 MYRAKDGGRAKYRVF 523
smart00267  149 LYQAKKAGRNQVAVY 163

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

110022

pfam00990

GGDEF

GGDEF domain

false

160

3e-41

165.88

98.75

4,350,0,32,383,32,57,440,91,27,477,118,40

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 351 ALHDSLTGLPNRALFSDRLSQAIARSKLPGGPqYAVLFLDVDRFKGINDTLGHPTGDAMLVEMARRLRACLRATDTVARL 430
pfam00990     1 AAHDPLTGLPNRRYFEEELEQELQRAQRRQSP-LALLLLDLDNFKRINDTYGHAVGDEVLQEVAQRLSSSLRRSDLVARL 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 431 GGDEFTILLE--PLQSTEQAAQVAARIQDALRRPMQMPAagpgglpggwHQVTMSASLGIVHSQPDYDSAMAVLRDADIA 508
pfam00990    80 GGDEFAILLPdtSLEGAQELAERIRRLLAALKIPHTLSG----------LPLYVTISIGIAAYPNDGEDAEDLLKRADQA 149


                ....*....
gi 15805493 509 MYRAKDGGR 517
pfam00990   150 LYQAKNQGR 158

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

32381

COG2199

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction...

false

181

2e-40

162.60

98.34

5,334,3,48,383,51,56,440,107,25,475,132,29,504,162,19

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 335 ARTAELEALSRQLQHDALHDSLTGLPNRALFSDRLSQAIARSKLPGGPqYAVLFLDVDRFKGINDTLGHPTGDAMLVEMA 414
COG2199       4 RLLTRLRKAEERLERLALHDPLTGLPNRRAFEERLERALARARRHGEP-LALLLLDLDHFKQINDTYGHAAGDEVLREVA 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 415 RRLRACLRATDTVARLGGDEFTILLePLQSTEQAAQVAARIQDALRRPMQMpaagpgglpgGWHQVTMSASLGIVHSQPD 494
COG2199      83 RRLRSNLREGDLVARLGGDEFAVLL-PGTSLEEAARLAERIRAALEEPFFL----------GGEELRVTVSIGVALYPED 151

                       170       180       190
                ....*....|....*....|....*....|
gi 15805493 495 YDSAMAVLRD-ADIAMYRAKDGGRAKYRVF 523
COG2199     152 GSDDAELLLRrADLALYRAKRAGRNRVVVF 181

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

129356

TIGR00254

GGDEF

diguanylate cyclase (GGDEF) domain

false

165

1e-32

137.08

99.39

4,350,1,27,378,28,61,440,89,19,467,108,57

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 351 ALHDSLTGLPNRALFSDRLSQAIARSKlPGGPQYAVLFLDVDRFKGINDTLGHPTGDAMLVEMARRLRACLRATDTVARL 430
TIGR00254     2 AVRDPLTGLYNRRYLEEMLDSELKRAR-RFQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRY 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 431 GGDEFTILLePLQSTEQAAQVAARIQDALrrpmqmpaAGPGGLPGGWHQVTMSASLGIVHSQPDYDSAMAVLRDADIAMY 510
TIGR00254    81 GGEEFVVIL-PGTPLEDALSKAERLRDAI--------NSKPIEVAGSETLTVTVSIGVACYPGHGLTLEELLKRADEALY 151

                       170
                ....*....|....
gi 15805493 511 RAKDGGRAKYRVFT 524
TIGR00254   152 QAKKAGRNRVVVAD 165

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

138661

PRK11596

EAL domain-containing protein; Provisional

false

255

4e-06

48.94

83.14

8,548,28,13,562,41,16,578,59,8,586,68,11,603,79,20,624,99,30,658,129,22,685,151,89

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 549 ELRVRYQPVLDLDrGRIEGFEALVRWQHPE--RGLLGPDD-FTPIAEESGLLpdidrwVLARACRELVQWQRLYPHDPpL 625
PRK11596     29 ERAYTFQPIYRTC-GRLMAVELLTVVTHPSnpSQRLSPDRyFAEITVSHRLD------VVKEQLDLLAQKADFFVRHG-L 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 626 HLSVNFCSQHLAAPDVHERVKELLQRTGFdpgrLNLEITESSLLSQTGDVQRNMErlrqlGVRLHLDDFGTGYSSLSYLQ 705
PRK11596    101 LASVNIDGPTLIALRQQPKILRLIERLPW----LRFELVEHIRLPKDSTFASMCE-----FGPLWLDDFGTGMANFSALS 171

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15805493 706 LYPIDVLKIDRSFVQGMLDNDSNAELVRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFS 774
PRK11596    172 EVRYDYIKVARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQRSPAFAAQGYFLS 240

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

128397

smart00086

PAC

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

true

false

0.006

38.32

100.00

1,272,0,43

                        10        20        30        40
                ....*....|....*....|....*....|....*....|...
gi 15805493 273 QFEERMLRPDGEPVYQLRNYTPLFDENGELLLYLGHGVDVTEL 315
smart00086    1 TVEYRLRRKDGSYIWVLVSASPIRDEDGEVEGILGVVRDITER 43

smart00086

128397

PAC

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

-1

137662

PRK10060

RNase II stability modulator; Provisional

false

true

false

663

7e-101

363.67

66.67

9,308,219,17,334,236,3,353,239,23,379,262,61,442,323,8,450,332,18,478,350,82,561,432,56,620,488,173

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 309 GVDVTELRRTQEALRELnaqleerveARTaelealsrqlqhdalhDSLTGLPNRALFSDRLSQAIARSklpGGPQYAVLF 388
PRK10060    220 GTDITEERRAQERLRIL---------ANT----------------DSITGLPNRNAIQELIDHAIAQA---DNNQVGIVY 271

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 389 LDVDRFKGINDTLGHPTGDAMLVEMARRLRACLRATDTVARLGGDEFTILLEplQSTEQAAQ-VAARIQDALRRPMQMPA 467
PRK10060    272 LDLDNFKKVNDAYGHMFGDQLLQDVSLAILSCLEEDQTLARLGGDEFLVLAS--HTSQAALEaMASRILTRLRLPFRIGL 349

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 468 AgpgglpggwhQVTMSASLGIVHSQPDYDSAMAVLRDADIAMYRAKDGGRAKYRVFTPEMREHILHVNRMEHELRRALAA 547
PRK10060    350 I----------EVYTGCSIGIALSPEHGDDSESLIRSADTAMYTAKEGGRGQFCVFSPEMNQRVFEYLWLDTNLRKALEN 419

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 548 DELRVRYQPVLDLdRGRIEGFEALVRWQHPERGLLGPDDFTPIAEESGLLPDIDRWVLARACRELVQWQRlypHDPPLHL 627
PRK10060    420 DQLVIHYQPKITW-RGEVRSLEALVRWQSPERGLIPPLEFISYAEESGLIVPLGRWVILDVVRQAAKWRD---KGINLRV 495

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 628 SVNFCSQHLAAPDVHERVKELLQRTGFDPGRLNLEITESSLLSQTGDVQRNMERLRQLGVRLHLDDFGTGYSSLSYLQLY 707
PRK10060    496 AVNVSARQLADQTIFTALKQVLQELNFEYCPIDVELTESCLIENEELALSVIQQFSQLGAQVHLDDFGTGYSSLSQLARF 575

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 708 PIDVLKIDRSFVQGMLDNDSNAELVRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFSPALDVHAARTLVA 787
PRK10060    576 PIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVETAKEDAFLTKNGVNERQGFLFAKPMPAVAFERWYK 655


                ....*.
gi 15805493 788 EGQHHR 793
PRK10060    656 RYQKLR 661

-1

34606

COG5001

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF...

false

true

false

663

1e-87

319.66

66.82

4,323,200,54,378,254,90,478,344,137,621,481,162

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 324 ELNAQLEERVEARTAELEALSRQLQHDALHDSLTGLPNRALFSDRLSQAIARSKlPGGPQYAVLFLDVDRFKGINDTLGH 403
COG5001     201 SDMVQSQVTLTQRAEETRRLSDENDRLANLDSLTGLPNRRRFFAELDARLAAAR-QSGRRLVLGVIDLDGFKPVNDAFGH 279

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 404 PTGDAMLVEMARRLRACLRATDTVARLGGDEFTILLEPLQSTEQAAQVAARIQDALRRPMQMPAAgpgglpggwhQVTMS 483
COG5001     280 ATGDRLLIEVGRRLKAFDGAPILAARLGGDEFALIIPALEDDALRVAGARALCESLQAPYDLRGV----------RVQVG 349

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 484 ASLGIVHSQPDYDSAMAVLRDADIAMYRAKDGGRAKYRVFTPEMREHILHVNRMEHELRRALAADELRVRYQPVLDLDRG 563
COG5001     350 ASIGIAPFPSGADTSEQLFERADYALYHAKQNGKGAAVLFDARHEAAIRDMAVVEQALRSADLEQELSVHFQPIVDIVSG 429

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 564 RIEGFEALVRWQHPERGLLGPDDFTPIAEESGLLPDIDRWVLARACRELVQWqrlyphDPPLHLSVNFCSQHLAAPDVHE 643
COG5001     430 KTIALEALARWHSPEIGPVPPDVFIGIAERSGQIVELTRLLLAKALREARAW------PMDVRVSINLSARDLASMENVR 503

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 644 RVKELLQRTGFDPGRLNLEITESSLLSQTGDVQRNMERLRQLGVRLHLDDFGTGYSSLSYLQLYPIDVLKIDRSFVQGML 723
COG5001     504 RLLAIVSESCIAPHRLDFEITETAIVCDFDQARDALAALHELGVRTALDDFGTGYSSLSHLRALPLDKIKIDRSFVSDLE 583

                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 724 DNDSNAELVRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFSPALDVHAAR 783
COG5001     584 ENPTSEDIVRTVLQLGRNLRMECVVEGVETEAQRDRVAALGATVMQGYHYARPMPAEERR 643

-1

138538

PRK11359

cAMP phosphodiesterase; Provisional

false

true

false

799

4e-74

274.80

56.45

10,299,331,13,312,345,25,338,370,7,352,377,20,377,397,58,436,455,35,481,490,10,491,501,6,500,507,125,627,632,150

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 300 GELLLYLGHGVDV-TELRRTQEALRELNAQLEERVEARTaELEALSRqlqhdalHDSLTGLPNRALFSDRLSQAiarskL 378
PRK11359    332 GILQIKTSSGAETsAFIERVADISQHMAALALEQEKSRQ-HIEQLIQ-------FDPMTGLPNRNNLHNYLDDL-----V 398

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 379 PGGPQYAVLFLDVDRFKGINDTLGHPTGDAMLVEMARRLRACLRATDTVARLGGDEFtILLEPLQSTEQAAQVAARIQDA 458
PRK11359    399 DKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRIEGTQF-VLVSLENDVSNITQIADELRNV 477

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 459 LRRPMQMPAAGPGglpggwhqvtMSASLGIVHS-QPDYDSamaVLRDADIAMYRAKDGGRAKYRVFTPEMREHILHVNRM 537
PRK11359    478 VSKPIMIDDKPFP----------LTLSIGISYDvGKNRDY---LLSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVL 544

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 538 EHELRRALAADELRVRYQPVLDLDRGRIEGFEALVRWQHPERGLLGPDDFTPIAEESGLLPDIDRWVLARACRELVQWQR 617
PRK11359    545 GAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRS 624

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 618 LYPHDPPLhlSVNFCSQHLAAPDVHERVKELLQRTGFDPGRLNLEITESSLLSQTGDVQRNMERLRQLGVRLHLDDFGTG 697
PRK11359    625 QNIHIPAL--SVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGTG 702

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 698 YSSLSYLQLYPIDVLKIDRSFVQGMLDNDSNAELVRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFSPAL 777
PRK11359    703 FSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPL 782

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

4e-68

255.01

37.72

8,338,675,42,381,717,58,440,775,20,467,795,13,482,808,56,538,866,33,571,900,33,608,933,163

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493  339 ELEALSRQLQHDALHDSLTGLPNRALFSDRLSQAIARSKLPGgPQYAVLFLDVDRFKGINDTLGHPTGDAMLVEMARRLR 418
PRK09776     676 ESRAMLRQLSYSASHDALTGLANRASFEKQLREALQTVNSTH-QRHALVFIDLDRFKAVNDSAGHAAGDALLRELASLML 754

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493  419 ACLRATDTVARLGGDEFTILLePLQSTEQAAQVAARIQDALRrpmqmpaAGPGGLPGGWHQVtmSASLGIVHSQPDYDSA 498
PRK09776     755 SMLRSSDVLARLGGDEFGLLL-PDCNVESARFIATRIISAIN-------DYRFPWEGRVYRV--GASAGITAIDDNNHQA 824

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493  499 MAVLRDADIAMYRAKDGGRAKYRVFTPEMREHILHVNRME--HELRRALAADELRVRYQPVLDLDRGRIEGFEAL-VRWQ 575
PRK09776     825 SEVMSQADIACYAAKNAGRGRVTVYEPQQAAAHSERRELSlaEQWRSMLEENQLMLQAQEIASPRIPEARNLWLIsLRLW 904

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493  576 HPERGLLGPDDFTPIAEESGLLPDIDRWVlaraCRELVQWQRLYPHDPPLHLSVNFCSQHLAAPDVHERVKELLQRTGFD 655
PRK09776     905 DCEGEIIDEGAFRPAAEDPALMHALDRWV----IHELFQQGARAVASKGLSIAIPLSVASLSSATLLPFLLEQLENSPLP 980

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493  656 PGRLNLEITESSLLSQTGDVQRNMERLRQLGVRLHLDDFGTGYSSLSYLQLYPIDVLKIDRSFVQGMLDNDSNAELVRTI 735
PRK09776     981 PRLLHLEITETALLNHAEAASRLVQKLRLAGCRVVLDDFGRGLSSFNYLKAFMADYLKIDGELCANLQGNLMDEMLVSII 1060

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 15805493  736 VAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGF 771
PRK09776    1061 NGIAQRLGMKTIAGPVELPLTLDTLSGIGVDLAQGY 1096

-1

139666

PRK13561

putative phosphodiesterase; Provisional

false

true

false

651

6e-62

234.28

66.67

9,340,217,6,346,226,29,380,255,88,478,343,17,496,360,121,620,481,87,707,571,20,730,591,47,777,640,11

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 341 EALSRQ---LQHDALHDSLTGLPNRALFSDRLSQAIARsklpgGPQYAVLFLDVDRFKGINDTLGHPTGDAMLVEMARRL 417
PRK13561    218 QLLQRHyeeQNENAMRFPVSDLPNKALLMALLEQVVAR-----KQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKL 292

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 418 RACLRATDTVARLGGDEFTILLEPLQSTEQAAQVAARIQDALRRPMQMPAAgpgglpggwhQVTMSASLGIVHSQPDYdS 497
PRK13561    293 KSVLSPRMVLAQISGYDFAIIANGVKEPWHAITLGQQVLTIINERLPIQRI----------QLRPSCSIGIAMFYGDL-T 361

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 498 AMAVLRDADIAMYRAKDGGRAKYRVFTPEMREHILHVNRMEHELRRALAADELRVRYQPVLDLDRGRIEGFEALVRWQHP 577
PRK13561    362 AEQLYSRAVSAAFTARRKGKNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMRSGKLVSAEALLRMQQP 441

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 578 ERGLLGPDDFTPIAEESGLLPDIDRWVLARACRELVQWQRlypHDPPLHLSVNFCSQHLAAPDVHERVKELLQRTGFDPG 657
PRK13561    442 DGSWDLPDGLIDRIESCGLMVTVGHWVLEESCRLLAAWQE---RGIMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPG 518

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 658 RLNLEITESSLLSQTGDVQRNMERLRQLGVRLHLDDFGTGYSSLSYLQLY---PIDVLKIDRSFVQGMLDNDSnaeLVRT 734
PRK13561    519 TLILEVTESRRIDDPHAAVAILRPLRNAGVRIALDDFGMGYAGLRQLQHMkslPIDVLKIDKMFVDGLPEDSS---MVAA 595

                       410       420       430       440       450
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 15805493 735 IVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFSPAL--DVHAARTLVAE 788
PRK13561    596 IIMLAQSLNLQMIAEGVETEAQRDWLAKAGVGVAQGFLFARPLpiEIFEERYLSEK 651

-1

34551

COG4943

Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]

Predicted signal transduction protein containing sensor and EAL domains [Signal...

false

true

false

524

8e-54

207.50

45.61

3,538,270,83,624,353,47,672,400,109

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 539 HELRRALAADELRVRYQPVLDLDRGRIEGFEALVRWQHPERGLLGPDDFTPIAEESGLLPDIDRWVLARACRELVQWQRL 618
COG4943     271 RRLQRAIERRELCVHYQPIVDLATGKCVGAEALARWPQEDGTVVSPDVFIPLAEESGMIEQITDYVIRNVFRDLGDLLRQ 350

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 619 YPHdppLHLSVNFCSQHLAAPDVHERVKELLQRTGFDPGRLNLEITESSLLSQtGDVQRNMERLRQLGVRLHLDDFGTGY 698
COG4943     351 HRD---LHVSINLSASDLASPRLIDRLNRKLAQYQVRPQQIALELTERTFADP-KKMTPIILRLREAGHEIYIDDFGTGY 426

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 699 SSLSYLQLYPIDVLKIDRSFVQGMLDNDSNAELVRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFSPALD 778
COG4943     427 SNLHYLQSLPVDALKIDKSFVDTLGTDSASHLIAPHIIEMAKSLGLKIVAEGVETEEQVDWLRKRGVHYGQGWLFSKALP 506


                ...
gi 15805493 779 VHA 781
COG4943     507 AQA 509

-1

138768

PRK11829

biofilm formation regulator HmsP; Provisional

false

true

false

728

7e-52

201.08

55.91

7,355,304,25,382,329,81,475,410,7,482,419,134,619,553,84,703,640,24,730,664,47

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 356 LTGLPNRALFSDRLSQAIARSKLPGgpQYAVLFLDVDRFKGINDTLGHPTGDAMLVEMARRLRACLRATDTVARLGGDEF 435
PRK11829    305 VTELPNRSLFISLLEKEIASSTRTD--HFHLLVIGIETLQEVSGAMSEAQHQQLLLTIVQRIEQCIDDSDLLAQLSKTEF 382

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 436 TILLEPLQSTEQAAQVAARIQDALRRPMqmpaagpgglpgGWHQVTM--SASLGIVHSQPDYDSAMAVLRDADIAMYRAK 513
PRK11829    383 AVLARGTRRSFPAMQLARRIMSQVTQPL------------FFDEITLrpSASIGITRYQAQQDTAESMMRNASTAMMAAH 450

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 514 DGGRAKYRVFTPEMREHILHVNRMEHELRRALAADELRVRYQPVLDLDRGRIEGFEALVRWQHPERGLLGPDDFTPIAEE 593
PRK11829    451 HEGRNQIMVFEPHLIEKTHKRLTQENDLLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWCQPDGSYVLPSGFVHFAEE 530

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 594 SGLLPDIDRWVLARACRELVQWQrlyPHDPPLHLSVNFCSQHLAAPDVHERVKELLQRTGFDPGRLNLEITESSLLSQTG 673
PRK11829    531 EGMMVPLGNWVLEEACRILADWK---ARGVSLPLSVNISGLQVQNKQFLPHLKTLISHYHIDPQQLLLEITETAQIQDLD 607

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 674 DVQRNMERLRQLGVRLHLDDFGTGYSSLSY---LQLYPIDVLKIDRSFVQGMLDNDSnaeLVRTIVAMAKNLNLKVVAEG 750
PRK11829    608 EALRLLRELQGLGLLIALDDFGIGYSSLRYlnhLKSLPIHMIKLDKSFVKNLPEDDA---IARIISCVSDVLKVRVMAEG 684

                       410       420
                ....*....|....*....|....*..
gi 15805493 751 IEDPRQLAALRGLGCDAGQGFLFSPAL 777
PRK11829    685 VETEEQRQWLLEHGIQCGQGFLFSPPL 711

-1

137979

PRK10551

hypothetical protein; Provisional

false

true

false

518

1e-39

160.60

46.91

3,535,262,85,622,347,49,672,396,109

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 536 RMEHELRRALAADELRVRYQPVLDLDRGRIEGFEALVRWQHPERGLLGPDDFTPIAEESGLLPDIDRWVLARACRELVQW 615
PRK10551    263 RPGREILTAIKREQFYVVYQPVVDTQTLRVTGLEVLLRWRHPTAGEIPPDAFINYAEAQKLIVPLTQHLFELIARDAAEL 342

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 616 QRLYPhdPPLHLSVNFCSQHLAAPDVHERVKELLQRTGFDPGRLNLEITESSLLSQtGDVQRNMERLRQLGVRLHLDDFG 695
PRK10551    343 QKVLP--VGAKLGINIAPAHLHSDSFKADVQRLLASLPADHFQIVLEITERDMLQE-EEALKLFAWLHSQGIEIAIDDFG 419

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 696 TGYSSLSYLQLYPIDVLKIDRSFVQGMLDNDSNAELVRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFSP 775
PRK10551    420 TGHSALIYLERFTLDYLKIDRGFINAIGTETVTSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLREHGVNFLQGYWISR 499


                ....*.
gi 15805493 776 ALDVHA 781
PRK10551    500 PLPLDD 505

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

2e-33

139.67

45.06

6,322,239,17,339,258,43,383,301,56,440,357,21,462,378,11,479,389,46

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 323 RELNAQLEERVEARTAE--LEALSRQLQHDALHDSLTGLPNRALFSDRLSQAIARSKLPGGPqYAVLFLDVDRFKGINDT 400
COG3706     240 GELRARLRRQLRRKRYErqLRESLERLQELALVDGLTGLFNRRYFDEHLADLWKRALREGRP-LSLLMLDIDDFKEINDT 318

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 401 LGHPTGDAMLVEMARRLRACLRATDTVARLGGDEFTILLePLQSTEQAAQVAARIQDALRRpMQMPAAGPGGLpggwhqV 480
COG3706     319 YGHDVGDEVLRQVARRLRQTVRGLDLVARYGGEEFAVVL-PDTDLEAAIAIAERIRQKINE-LPFVHELSREP------L 390

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 15805493 481 TMSASLGIVHSQPDYDSAMAVLRDADIAMYRAKDGGRAKYRVFTP 525
COG3706     391 EVTISIGVAEGKPGEDSIEELLKRADKALYKAKASGRNRVVVKRA 435

-1

137400

PRK09581

pleD

response regulator PleD; Reviewed

false

true

false

457

3e-29

125.80

50.55

11,287,218,4,291,227,5,296,236,8,304,253,11,315,266,1,316,268,18,335,286,5,350,291,32,383,323,56,440,379,16,463,395,54

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 288 QLRN-----YTPLF----DENGELLL---------YLGHGVDVTEL--R-RTQEALRELNAQLEERVEaRTAELealsrq 346
PRK09581    219 QLRSkertrYVPILllvdEDEDPRLVkalelgvndYLMRPIDKNELlaRvRTQIRRKRYQDALRQNLE-QSIEM------ 291

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 347 lqhdALHDSLTGLPNRALFSDRLSQAIARSKLPGGPqYAVLFLDVDRFKGINDTLGHPTGDAMLVEMARRLRACLRATDT 426
PRK09581    292 ----AVTDGLTGLHNRRYFDMHLKQLIERANERGKP-LSLMMLDIDHFKQVNDTYGHDAGDEVLREFAKRLRKNIRGTDL 366

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 427 VARLGGDEFTILLePLQSTEQAAQVAARIQdalrrpmQMPAAGPGGLPGGWHQVTMSASLGIVHSQPDYDSAMAVLRDAD 506
PRK09581    367 IARYGGEEFVVVM-PDTDIEVAIAVAERIR-------RKIAEEPFAISDGKERLNVTVSIGVAELRPSGESIEALIKRAD 438

                       250
                ....*....|.
gi 15805493 507 IAMYRAKDGGR 517
PRK09581    439 KALYEAKNTGR 449

-1

137576

PRK09894

hypothetical protein; Provisional

false

true

false

293

8e-23

104.41

59.73

7,329,107,18,347,126,15,362,142,17,383,159,56,440,215,19,468,234,26,495,260,22

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 330 EERVEARTAELEALSRQL-QHDALHDSLTGLPNR-ALFSDRLSQAIARSKLPggpqYAVLFLDVDRFKGINDTLGHPTGD 407
PRK09894    108 QEGLLSFTAALTDYKIYLlTIRSNMDVLTGLPGRrVLDESFDHQLRNREPLN----LYLALLDIDRFKLVNDTYGHLIGD 183

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 408 AMLVEMARRLRACLRATDTVARLGGDEFTILLePLQSTEQAAQVAARIQDALrrpmqmpaaGPGGLPGGWHQVTMSASLG 487
PRK09894    184 VVLRTLATYLASWTRPYETVYRYGGEEFIIIL-KAATDEEACRAGERIRQLI---------ANQAITHSEGRINITATFG 253

                       170       180       190
                ....*....|....*....|....*....|
gi 15805493 488 IVHSQPDyDSAMAVLRDADIAMYRAKDGGR 517
PRK09894    254 VTRAFPE-EPLDEVIGRADRAMYEGKQAGR 282

-1

138376

PRK11059

regulatory protein CsrD; Provisional

false

true

false

642

2e-22

102.65

68.69

18,315,196,10,328,206,9,337,217,9,349,226,34,384,260,37,421,298,6,427,305,12,440,317,21,464,338,14,485,352,9,495,361,13,508,387,2,510,390,5,515,399,8,540,407,21,562,428,54,621,482,25,646,508,129

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 316 RRTQEALRELnaqLEERVEART--AELEALSRQlqhDALHDSLTGLPNRALFSDRLSQAIARSKLPGGPQyAVLFLDVDR 393
PRK11059    197 RLASRALDHL---LEELQDARKerSRFDTFIRS---NAFLDAKTGLGNRLFFDNQLDTLLEDQEKVGAHG-VVMLIRLPD 269

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 394 FKGINDTLGHPTGDAMLVEMARRLRACL-RATDTV-ARLGGDEFTILLePLQSTEQAAQVAARIQDALRRpmqMPAAGPG 471
PRK11059    270 FDLLQEELGESQVDELLFELINLLSTFVqRYPGALlARYSRSDFAVLL-PHRSLKEADSLASQLLKAVDS---LPPPKML 345

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 472 GLPGGWHqvtmsasLGIVHSQPDyDSAMAVLRDADIA-------------MY-RAKDG----GRAKYRVFtpemrehilh 533
PRK11059    346 DRDDFLH-------IGIAAYRSG-QSTEQVMEEAEMAlrsaqlqggnswfMYdKAQDPekgrGSVRWRTL---------- 407

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 534 vnrmeheLRRALAADELRVRYQPVLDLDrGRIEGFEALVRWQHPERGLLGPDDFTPIAEESGLLPDIDRWVLARACRELV 613
PRK11059    408 -------LEQALVRGGPRLYQQPVVTRD-GQVHHRELMCRIRDGQGNEVRAAEFMPMVLQCGLSEQYDRQVIERVLPLLS 479

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 614 QWQrlyphDPPLHLSVNFCSQHLAAPDVHERVK-ELLQRTGFDPGRLNLEITESSLLSQTGDVQRNMERLRQLGVRLHLD 692
PRK11059    480 YWP-----EESQNLSINLSVDSLLSRAFQRWLRdTLLQCERSQRKRLIFELAEADVVQHIDRLRPVLRMLRGLGCRLAVD 554

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 693 DFGTGYSSLSYLQLYPIDVLKIDRSFVQGMLDNDSNAELVRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFL 772
PRK11059    555 QAGLTVVSTSYIKELNVELIKLHPSLVRNIHQRTENQLFVRSLVGACAGTETQVFAEGVESREEWQTLQILGVSGGQGDF 634


                ...
gi 15805493 773 FSP 775
PRK11059    635 FAS 637

-1

137615

PRK09966

hypothetical protein; Provisional

false

true

false

407

1e-21

100.86

43.73

5,322,220,9,332,229,45,379,274,89,477,363,15,493,378,20

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 323 RELNAQLEErVEARTAELEALSRQLQHDALHDSLTGLPNRALFSDRLSQAIARSKlpGGPQYAVLFLDVDRFKGINDTLG 402
PRK09966    221 LDFNSLLDE-MEEWQLRLQAKNAQLLRTALHDPLTGLANRAAFRSGINTLMNNSD--ARKTSALLFLDGDNFKYINDTWG 297

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 403 HPTGDAMLVEMARRLRACLRATDTVARLGGDEFTILLEPLQSTEQAAQVAARIQDALRRPMQMPAAgpgglpggwHQVTM 482
PRK09966    298 HATGDRVLIEIAKRLAEFGGLRHKAYRLGGDEFAMVLYDVQSESEVQQICSALTQIFNLPFDLHNG---------HQTTM 368

                       170       180       190
                ....*....|....*....|....*....|.
gi 15805493 483 SASLGIVHSQpDYDSAMAVLRDADIAMYRAK 513
PRK09966    369 TLSIGYAMTI-EHASAEKLQELADHNMYQAK 398

-1

137770

PRK10245

adrA

diguanylate cyclase AdrA; Provisional

false

true

false

371

2e-16

83.02

44.74

5,344,203,18,367,221,17,384,242,55,439,299,25,477,324,45

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 345 RQLQHDALHDSLTGLPNRalfsdRLSQAIARSKLPGGPQY----AVLFLDVDRFKGINDTLGHPTGDAMLVEMARRLRAC 420
PRK10245    204 RRLQVMSTRDGMTGVYNR-----RHWETMLRNEFDNCRRHnrdaTLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQIT 278

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 421 LRATDTVARLGGDEFTILL--EPLQSTEQAAQVAARIQDALRRPMQmpaagpgglpggwHQVTMSASLGIVHSQPDYDSA 498
PRK10245    279 LRGSDVIGRFGGDEFAVIMsgTPAESAITAMLRVHEGLNTLRLPNA-------------PQVTLRISVGVAPLNPQMSHY 345

                       170       180
                ....*....|....*....|....
gi 15805493 499 MAVLRDADIAMYRAKDGGRAKYRV 522
PRK10245    346 REWLKSADLALYKAKKAGRNRTEV 369

-1

117025

pfam08448

PAS_4

PAS fold

true

false

110

1e-11

67.05

91.82

4,211,9,22,233,32,11,249,43,32,282,75,35

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 212 VLGPDQRYRFCNPAAIGNPQIR-EWIMGHTDAEYvaergFPPELATERGRHMDEAARERKTVQFEERMLRPdGEPVYQLR 290
pfam08448    10 VLDPDGRVRYANAAAAELFGLPpEELLGKTLAEL-----LPPEDAARLERALRRALEGEEPIDFLEELLLN-GEERHYEL 83

                        90       100
                ....*....|....*....|....*..
gi 15805493 291 NYTPLFDENGELLLYLGHGVDVTELRR 317
pfam08448    84 RLTPLRDPDGEVIGVLVISRDITERRR 110

-1

117025

pfam08448

PAS_4

PAS fold

true

false

110

7e-05

44.71

88.18

6,86,12,11,97,24,9,106,34,16,123,50,22,146,72,22,169,94,15

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493  87 RQGTVIHASEA-CGALGWSHD-LRGRPLAELLSSPLEDlRLSNLLKRVWQGERLHQVPLSLrHTEGRLQLAEASLLPLHA 164
pfam08448    13 PDGRVRYANAAaAELFGLPPEeLLGKTLAELLPPEDAA-RLERALRRALEGEEPIDFLEEL-LLNGEERHYELRLTPLRD 90

                        90       100
                ....*....|....*....|
gi 15805493 165 ASGEsTAAYVAMSITTTELH 184
pfam08448    91 PDGE-VIGVLVISRDITERR 109

-1

33240

COG3434

Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]

Predicted signal transduction protein containing EAL and modified HD-GYP domains [...

false

true

false

407

3e-04

42.57

27.27

4,653,80,16,671,96,29,700,130,19,732,149,42

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 654 FDPGRLNLEITESSLLsqTGDVQRNMERLRQLGVRLHLDDFGTGYSS-----LSYLQLYPIDVLKIDRSFVqgmldndsn 728
COG3434      81 LPPDKVVIEILEDCPP--TEKLLSAIKELKQKGYLLALDDFIFSNVSewkplLPLSDIVKIDFKRVTFDKA--------- 149

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 15805493 729 aelvRTIVAMAKNLNLKVVAEGIEDPRQLAALRGLGCDAGQGFLFS 774
COG3434     150 ----RLFDRDLGYINKKFLAEKVETEEEFEQAKKAGFDLFQGYFFS 191

-1

129332

TIGR00229

sensory_box

PAS domain S-box

false

true

false

124

5e-04

41.88

68.55

3,232,39,14,250,53,46,297,99,25

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 233 REWIMGHTDAEYVAergfPPELATERGRHMDEAARERKTVQFEERMLRPDGEPVYQLRNYTPLFdENGELLLYLGHGVDV 312
TIGR00229    40 AEELIGRNVLELIP----EEDREEVRERIERLLEGEREPYSEERRVRRKDGSEIWVEVSVSPIR-TNGGELGVVGIVRDI 114

                        90
                ....*....|
gi 15805493 313 TELRRTQEAL 322
TIGR00229   115 TERKQAEEAL 124

-1

139664

PRK13558

bacterio-opsin activator; Provisional

false

true

false

674

0.002

40.17

11.87

3,250,215,8,263,223,61,325,284,11

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 251 PPELATERgrhmdEAARERKTVQFEERMLRPDGEPVYQLRNYTPLFDENGELLLYLGHGVDVTELRRTQEALRElNAQLE 330
PRK13558    216 EDRVAEFW-----TAITEDHDTQVVLRNYRRDGSLFWNQVDISPIYDEDGTVSHYVGFQMDVSERMAAQQELQG-ERQSL 289


                ....*.
gi 15805493 331 ERVEAR 336
PRK13558    290 DRLLDR 295

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

0.002

39.69

5.82

3,259,490,25,285,515,7,292,523,32

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15805493  260 RHMDEAARERKTVQFEERMLRPDGEpVYQLRNY-TPLFDENGELLLYLGHGVDVTELRRTQEALRE 324
PRK09776     491 KEIRDALQGRSPFKLEFRIVVPDGE-IRHIRALaNRVLNKDGEVERLLGINMDMTEVRQLNEALFE 555

-1

33926

COG4191

Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms]

Signal transduction histidine kinase regulating C4-dicarboxylate transport system [...

true

false

603

0.004

39.10

9.45

3,314,321,36,350,358,13,365,371,7

                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15805493 315 LRRTQEALRELNAQLEERVEARTAELEALSRQLQHD-ALHDSLTGLPNRAlfSDRLSQA 372
COG4191     322 ARLRLAELQEARAELERRVEERTADLTRANARLQAEiAEREQAEAALRRA--QDELVQA 378

-1

139665

PRK13559

hypothetical protein; Provisional

false

true

false

363

0.005

38.65

29.48

7,265,113,7,273,120,44,330,164,8,340,172,10,350,187,13,363,204,7,370,214,6

                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15805493 266 ARERKTVqFEERMLRPDGEPVYQLRNYTPLFDENGELLLYLGHGVDVTELRRtqealrelnaqleERVEARTAelEALSR 345
PRK13559    114 AAERVVV-VELLNYRKDGSPFWNALHLGPIYDEDGKLLYFFGSQWDVTDIRA-------------VRALEAHE--RRLAR 177

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 15805493 346 QLQHD-----ALHDSLTGLPNRA----LFSDRLS---QAIARS 376
PRK13559    178 EVDHRsknvfAVVDSIVRLTGRAddasLYAAAIQervQALARA 220

-1

active site	0	10	10	true	133472	cd01949	GGDEF
I-site	1	3	3	true	133472	cd01949	GGDEF