NCBI Conserved Domain Search

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Conserved domains on [gi\|117929306\|ref\|YP_873857.1\|]
response regulator receiver modulated diguanylate phosphodiesterase [Acidothermus cellulolyticus 11B]

Graphical summary show options »	Show site features Horizontal zoom: ×	?



List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

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of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

30163

cd01948

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

true

false

true

240

7e-41

163.08

97.92

6,177,5,6,184,11,31,215,44,36,251,83,17,270,100,7,277,115,125

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 178 AIADDTaLTTVFQPIIRLADTEVVGFEALSRFADPAGT--PPDRWFSEASSVGLGPDLELKAMHTALQYLPTIPDG---V 252
cd01948        6 ALERGE-FELYYQPIVDLRTGRIVGYEALLRWRHPEGGliSPAEFIPLAEETGLIVELGRWVLEEACRQLARWQAGgpdL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 253 FLALNASPELVLSRKLenLQDVSSL--------DRLVLELTEHAAVEDYGVIQERLAPFREKGMRVAIDDTGAGFASLRH 324
cd01948       85 RLSVNLSARQLRDPDF--LDRLLELlaetglppRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYSSLSY 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117929306 325 ILLLQPEIIKLDISITRSIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAPRPA 402
cd01948      163 LKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAEE 240

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

29071

cd00156

REC

Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; contains a phosphoacceptor site that is phosphorylated by histidine kinase homologs; usually found N-terminal to a DNA binding effector domain; forms homodimers

Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC,...

true

false

true

113

6e-23

103.78

100.00

3,18,0,23,42,23,41,85,64,49

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  19 LVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRslEDAEYLPILVLTA 98
cd00156        1 LIVDDDPLIRELLRRLLEKEGYE-VVEAEDGEEALALLAEEKPDLILLDIMMPGMDGLELLRRIR--KRGPDIPIIFLTA 77

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 117929306  99 DLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLL 134
cd00156       78 HGDDEDAVEALKAGADDYLTKPFSPEELLARIRALL 113

cl09944

142340

REC

Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC,...

32382

COG2200

Rtn

c-di-GMP phosphodiesterase class I (EAL domain) [Signal transduction mechanisms]

false

256

3e-38

154.33

89.06

5,184,16,31,215,49,35,250,86,13,263,103,15,278,120,124

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 185 LTTVFQPIIRLADTEVVGFEALSRFADPAGT--PPDRWFSEASSVGLGPDLELKAMHTALQYLPTIPD--GVFLALNASP 260
COG2200       17 FSLYYQPIVDLATGRIVGYEALLRWRHPDGGliSPGEFIPLAEETGLIVELGRWVLEEACRQLRTWPRagPLRLAVNLSP 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 261 ELV----LSRKLENLQDVSSLD--RLVLELTEHAAVEDYGVIQERLAPFREKGMRVAIDDTGAGFASLRHILLLQPEIIK 334
COG2200       97 VQLrspgLVDLLLRLLARLGLPphRLVLEITESALIDDLDTALALLRQLRELGVRIALDDFGTGYSSLSYLKRLPPDILK 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117929306 335 LDISITRSIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAPRPA 402
COG2200      177 IDRSFVRDLETDARDQAIVRAIVALAHKLGLTVVAEGVETEEQLDLLRELGCDYLQGYLFSRPLPADA 244

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

109613

pfam00563

EAL

EAL domain

false

236

5e-38

153.73

94.92

7,184,12,31,215,45,33,248,84,17,265,105,8,273,114,20,294,134,50,345,184,52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 185 LTTVFQPIIRLADTEVVGFEALSRFADPAGT--PPDRWFSEASSVGLGPDLELKAMHTALQYLPTI------PDGVFLAL 256
pfam00563     13 FSLYFQPIVDLRTGKVLGYEALLRWQHPDGGliPPDEFLPLAERLGLIAELDRWVLEKALAQLAEWrgnallPPDLPLSV 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 257 NASPELVLS----RKLENLQD-VSSLDRLVLELTEHAAVEDYgVIQERLAPFREKGMRVAIDDTGAGFASLRHILLLQPE 331
pfam00563     93 NLSPASLLDpsflEALLALKQgGLPPSRLVLEITESDLDEDL-RLLEALARLRSLGFRLALDDFGTGYSSLSYLSRLPPD 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117929306 332 IIKLDISITRSIDrDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRP 397
pfam00563    172 YIKIDRSFIKDLS-DPESRALLRALIALARELGIKVVAEGVETEEQLELLKELGIDYVQGYLFSKP 236

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

128367

smart00052

EAL

Putative diguanylate phosphodiesterase

false

241

5e-35

143.89

92.53

5,187,15,27,214,44,36,250,83,15,265,102,13,278,117,121

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 188 VFQPIIRLADTEVVGFEALSRFADPAG--TPPDRWFSEASSVGLGPDLELKAMHTALQYLPTIPD---GVFLALNASPEL 262
smart00052    16 YYQPIVSLRTGRLVGVEALIRWQHPEGgiISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQAqgpPLRISINLSARQ 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 263 VLS----RKLENLQDVSSLD--RLVLELTEHAAVEDYGVIQERLAPFREKGMRVAIDDTGAGFASLRHILLLQPEIIKLD 336
smart00052    96 LISpdlvPRVLELLEETGLPpqRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGYSSLSYLKRLPVDLLKID 175

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 117929306 337 ISITRSIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAP 399
smart00052   176 KSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLP 238

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

109140

pfam00072

Response_reg

Response regulator receiver domain

false

111

6e-25

110.36

100.00

3,17,0,24,42,24,46,90,70,41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAeyLPILVLT 97
pfam00072      1 VLIVDDDPLIRELLRQLLEKEGYV-VAEADDGEEALELLKEKRPDLILLDIRMPGMDGLELLRRIRRRPPT--TPVIVLT 77

                         90       100       110
                 ....*....|....*....|....*....|....
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFDATEVVLRVR 131
pfam00072     78 AHGDEEDAVEALKAGANDFLSKPFDPEELVAALR 111

cl09944

142340

REC

Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC,...

-1

31127

COG0784

CheY

FOG: CheY-like receiver [Signal transduction mechanisms]

false

130

3e-15

77.97

91.54

3,10,0,49,59,50,24,85,74,45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  11 ERFSDAHVLVVDDNEANVQLLEALLTRSGLRHVATARDGDEALRMVRDF-QPDLILLDLRMPKLDGYTVLERLRslEDAE 89
COG0784        1 LLLSGLRVLVVDDEPVNRRLLKRLLEDLGYEVVEAADGEEEALELLRELpQPDLILLDINMPGMDGIELLRRLR--ARGP 78

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 117929306  90 YLPILVLTADLTRDAVHRALDLGARDFLTKPFDATEVVLRV 130
COG0784       79 NIPVILLTAYADEADRERALAAGADDYLTKPIFLEEELLAA 119

cl09944

142340

REC

Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC,...

-1

128724

smart00448

REC

cheY-homologous receiver domain

false

5e-11

64.14

98.18

2,16,1,25,42,26,29

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 117929306  17 HVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMP 71
smart00448     2 RILVVDDDPLLRELLKALLEREGYE-VDEATDGEEALELLKEEKPDLILLDIMMP 55

cl09944

142340

REC

Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC,...

-1

138024

PRK10610

chemotaxis regulatory protein CheY; Provisional

false

129

2e-10

62.35

90.70

1,18,8,117

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  19 LVVDDNEANVQLLEALLTRSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAEYLPILVLTA 98
PRK10610       9 LVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGFGFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTA 88

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 117929306  99 DLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLLE 135
PRK10610      89 EAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFE 125

cl09944

142340

REC

Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC,...

-1

138661

PRK11596

EAL domain-containing protein; Provisional

false

255

3e-05

44.70

82.75

9,188,33,6,195,39,19,214,62,11,226,73,21,247,95,12,259,108,4,263,113,28,295,141,12,308,153,91

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 189 FQPIIRlADTEVVGFEALSRFADPAG----TPPDRWFSEASsVGLGPDLELKAMHTALQYLPT-IPDGVFLALNAS-PEL 262
PRK11596      34 FQPIYR-TCGRLMAVELLTVVTHPSNpsqrLSPDRYFAEIT-VSHRLDVVKEQLDLLAQKADFfVRHGLLASVNIDgPTL 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 263 V-LSRKLENLQDVSSLDRLVLELTEHAAVEdygvIQERLAPFREKGmRVAIDDTGAGFASLRHILLLQPEIIKLDISITR 341
PRK11596     112 IaLRQQPKILRLIERLPWLRFELVEHIRLP----KDSTFASMCEFG-PLWLDDFGTGMANFSALSEVRYDYIKVARELFV 186

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 117929306 342 SIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAP 399
PRK11596     187 MLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQRSPAFAAQGYFLSRPAP 244

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

34606

COG5001

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF...

false

true

false

663

1e-29

125.91

34.09

4,184,415,28,212,445,51,265,496,12,277,516,125

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 185 LTTVFQPIIRLADTEVVGFEALSRFADP--AGTPPDRWFSEASSVGLGPDLELKAMHTALQYLPTIPDGVFLALNASPEL 262
COG5001      416 LSVHFQPIVDIVSGKTIALEALARWHSPeiGPVPPDVFIGIAERSGQIVELTRLLLAKALREARAWPMDVRVSINLSARD 495

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 263 VlsRKLENLQDVSSL--------DRLVLELTEHAAVEDYGVIQERLAPFREKGMRVAIDDTGAGFASLRHILLLQPEIIK 334
COG5001      496 L--ASMENVRRLLAIvsesciapHRLDFEITETAIVCDFDQARDALAALHELGVRTALDDFGTGYSSLSHLRALPLDKIK 573

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117929306 335 LDISITRSIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAPRPA 402
COG5001      574 IDRSFVSDLEENPTSEDIVRTVLQLGRNLRMECVVEGVETEAQRDRVAALGATVMQGYHYARPMPAEE 641

-1

34551

COG4943

Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]

Predicted signal transduction protein containing sensor and EAL domains [Signal...

false

true

false

524

5e-25

110.43

42.94

8,184,281,31,215,314,28,243,346,7,251,353,6,257,365,5,262,372,10,274,382,16,291,398,108

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 185 LTTVFQPIIRLADTEVVGFEALSRFADPAGT--PPDRWFSEASSVGLGPDLELKAMHTALQ----YLPTIPDgVFLALN- 257
COG4943      282 LCVHYQPIVDLATGKCVGAEALARWPQEDGTvvSPDVFIPLAEESGMIEQITDYVIRNVFRdlgdLLRQHRD-LHVSINl 360

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 258 -----ASPEL--VLSRKLENLQdvSSLDRLVLELTEHAAVeDYGVIQERLAPFREKGMRVAIDDTGAGFASLRHILLLQP 330
COG4943      361 sasdlASPRLidRLNRKLAQYQ--VRPQQIALELTERTFA-DPKKMTPIILRLREAGHEIYIDDFGTGYSNLHYLQSLPV 437

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117929306 331 EIIKLDISITRSIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAP 399
COG4943      438 DALKIDKSFVDTLGTDSASHLIAPHIIEMAKSLGLKIVAEGVETEEQVDWLRKRGVHYGQGWLFSKALP 506

-1

137400

PRK09581

pleD

response regulator PleD; Reviewed

false

true

false

457

3e-24

108.08

28.01

4,15,2,21,37,23,61,98,85,7,106,92,38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  16 AHVLVVDDNEANVQLLEALLTrSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAEYLPILV 95
PRK09581       3 ARILVVDDIPANVKLLEAKLL-AEYYTVLTASSGAEAIEICEREQPDIILLDVMMPGMDGFEVCRRLKSDPATAHIPVVM 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 117929306  96 LTA-DLTRDAVhRALDLGARDFLTKPFDATEVVLRVRNLLETRALYRTLR 144
PRK09581      82 VTAlDDPSDRV-RGLEAGADDFLTKPINDVALFARVKSLTRLKMVIDELR 130

-1

133606

CHL00148

orf27

Ycf27; Reviewed

false

true

false

240

7e-22

100.12

48.75

5,13,4,27,41,31,46,90,77,8,98,86,7,106,93,28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  14 SDAHVLVVDDNEANVQLLEALLTRSGLrHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDaeyLPI 93
CHL00148       5 SKEKILVVDDEASIRRILETRLSIIGY-EVITASDGEEALKLFHQEQPDLVILDVMMPKLDGYGVCQEIRKESD---VPI 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 117929306  94 LVLTA-DLTRDAVhRALDLGARDFLTKPFDATEVVLRVRNLL 134
CHL00148      81 IMLTAlGDVSDRI-TGLELGADDYVVKPFSPKELEARIRSVL 121

-1

32386

COG2204

AtoC

Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]

Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding...

false

true

false

464

5e-20

94.21

27.37

3,15,4,26,42,30,46,90,76,55

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  16 AHVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAeyLPILV 95
COG2204        5 ARILVVDDDPDIRELLEQALELAGYE-VVTAESAEEALEALSESPFDLVLLDIRMPGMDGLELLKEIKSRDPD--LPVIV 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 117929306  96 LTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLLETRALYRTLRA 145
COG2204       82 MTGHGDIDTAVEALRLGAFDFLEKPFDLDRLLAIVERALELRELQRENRR 131

-1

137662

PRK10060

RNase II stability modulator; Provisional

false

true

false

663

5e-20

94.03

34.54

8,180,417,17,198,434,14,212,450,38,250,491,9,264,500,17,281,528,11,292,543,6,302,549,97

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 181 DDTALTTVFQPIIRLADtEVVGFEALSRFADP--AGTPPDRWFSEASSVGLGPDLELKAMHTALQYLPTIPD---GVFLA 255
PRK10060     418 ENDQLVIHYQPKITWRG-EVRSLEALVRWQSPerGLIPPLEFISYAEESGLIVPLGRWVILDVVRQAAKWRDkgiNLRVA 496

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 256 LNASpelvlSRKLENLQDVSSLDRLV-----------LELTEHAAVED----YGVIQErlapFREKGMRVAIDDTGAGFA 320
PRK10060     497 VNVS-----ARQLADQTIFTALKQVLqelnfeycpidVELTESCLIENeelaLSVIQQ----FSQLGAQVHLDDFGTGYS 567

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117929306 321 SLRHILLLQPEIIKLDISITRSIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAP 399
PRK10060     568 SLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVETAKEDAFLTKNGVNERQGFLFAKPMP 646

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

5e-20

93.83

34.25

3,9,126,35,45,161,102,147,268,7

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  10 LERFSDAHVLVVDDNEANVQLLEALLTRSGLRHVAtARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAE 89
COG3706      127 LPEDAPKKILVVDDDATQRERLRRILQVEGFRVVE-ATDGEEALLQLAELPPDLVLLDANMPDMDGLELCTRLRQLERTR 205

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  90 YLPILVLTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLLETRALYRTLRAHN-----IALSDEL 154
COG3706      206 DIPIILLSSKDDDELVVRAFELGVNDYITKPIEEGELRARLRRQLRRKRYERQLRESLerlqeLALVDGL 275

-1

31088

COG0745

OmpR

Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]

Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-...

false

true

false

229

1e-19

93.09

50.22

4,16,1,25,42,26,16,59,42,30,90,72,44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  17 HVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDfQPDLILLDLRMPKLDGYTVLERLRSLEDAEyLPILVL 96
COG0745        2 RILLVEDDPELAELLKEYLEEEGYE-VDVAADGEEALEAARE-QPDLVLLDLMLPDLDGLELCRRLRAKKGSG-PPIIVL 78

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 117929306  97 TADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLL 134
COG0745       79 TARDDEEDRVLGLEAGADDYLTKPFSPRELLARLRALL 116

-1

33243

COG3437

Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and an HD-GYP domain [...

false

true

false

360

2e-19

91.90

43.33

3,5,4,36,42,40,43,85,84,76

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306   6 ASGALERFSDAHVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSL 85
COG3437        5 MQGKNEPDEKLTVLLVDDEPDNLEALRQLLRMIGYR-VIEAENGEEALKLLQEEPPDLVLLDVRMPEMDGAEVLNKLKAM 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117929306  86 -EDAEYLPILVLTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLLETRALYRTLRAHNIALSDELEKRRAQD 161
COG3437       84 sPSTRRIPVILLTAYADSEDRQRALEAGADDYLSKPISPKELVARVSSHLQLKRNEDFLLDQNLYLELQELRRRTEE 160

-1

139666

PRK13561

putative phosphodiesterase; Provisional

false

true

false

651

1e-18

89.44

34.41

6,189,418,25,214,445,36,250,482,27,277,517,46,323,566,16,342,582,60

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 190 QPIIRLADTEVVGFEALSRFADPAG--TPPDRWFSEASSVGLGPDLELKAMHTALQYLPTIPD-GVFLALNASPELVLSR 266
PRK13561     419 QPQVEMRSGKLVSAEALLRMQQPDGswDLPDGLIDRIESCGLMVTVGHWVLEESCRLLAAWQErGIMLPLSVNLSALQLM 498

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 267 KLENLQDVSSL--------DRLVLELTEHAAVEDYGVIQERLAPFREKGMRVAIDDTGAGFASLR---HILLLQPEIIKL 335
PRK13561     499 HPNMVADMLELltryriqpGTLILEVTESRRIDDPHAAVAILRPLRNAGVRIALDDFGMGYAGLRqlqHMKSLPIDVLKI 578

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117929306 336 DISItrsIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAPRPA 402
PRK13561     579 DKMF---VDGLPEDSSMVAAIIMLAQSLNLQMIAEGVETEAQRDWLAKAGVGVAQGFLFARPLPIEI 642

-1

138540

PRK11361

acetoacetate metabolism regulatory protein AtoC; Provisional

false

true

false

457

1e-18

89.52

28.67

3,17,6,24,42,30,46,90,76,61

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAeyLPILVLT 97
PRK11361       7 ILIVDDEDNVRRMLSTAFALQGFE-THCANNGRTALHLFADIHPDVVLMDIRMPEMDGIKALKEMRSHETR--TPVILMT 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLLETRALYRTLRAHNIALS 151
PRK11361      84 AYAEVETAVEALRCGAFDYVIKPFDLDELNLIVQRALQLQSMKKEIRHLHQALS 137

-1

138538

PRK11359

cAMP phosphodiesterase; Provisional

false

true

false

799

2e-18

88.74

29.16

7,177,550,5,183,555,29,212,586,34,246,627,3,252,630,19,273,649,4,277,661,122

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 178 AIADDtALTTVFQPIIRLADTEVVGFEALSRFADP--AGTPPDRWFSEASSVGLGPDLELKAMHTALQYLP-------TI 248
PRK11359     551 AISNN-QLKLVYQPQIFAETGELYGIEALARWHDPlhGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAewrsqniHI 629

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 249 PdgvFLALNASPELVLSRKLENLqdVSSL--------DRLVLELTEHAAVEDYGVIQERLAPFREKGMRVAIDDTGAGFA 320
PRK11359     630 P---ALSVNLSALHFRSNQLPNQ--VSDAmhawgidgHQLTVEITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGTGFS 704

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117929306 321 SLRHILLLQPEIIKLDISITRSIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAP 399
PRK11359     705 GLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLP 783

-1

131922

TIGR02875

spore_0_A

sporulation transcription factor Spo0A

false

true

false

262

2e-17

85.23

45.42

2,17,4,19,36,24,99

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLT-RSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAEYLPILVL 96
TIGR02875      5 IVIADDNKEFCNLLKEYLAaQPDMEVVGVAHNGVDALELIKEQQPDVVVLDIIMPHLDGIGVLEKLNEIELSARPRVIML 84

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 117929306  97 TADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLLE 135
TIGR02875     85 SAFGQEKITQRAVALGADYYVLKPFDLEILAARIRQLAW 123

-1

131209

TIGR02154

PhoB

phosphate regulon transcriptional regulatory protein PhoB

false

true

false

226

5e-17

83.92

52.21

2,15,2,26,42,28,92

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  16 AHVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAEYLPILV 95
TIGR02154      3 RRILVVEDEPAIRELIAYNLEKAGYD-VVEAGDGDEALTLINERGPDLILLDWMLPGTSGIELCRRLRRRPETRAIPIIM 81

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 117929306  96 LTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLL 134
TIGR02154     82 LTARGEEEDRVRGLETGADDYITKPFSPRELLARIKAVL 120

-1

134369

PRK00742

chemotaxis-specific methylesterase; Provisional

false

true

false

345

2e-16

82.14

30.14

4,17,4,14,31,19,56,90,75,12,102,89,19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLL-EALLTRSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDaeyLPILVL 96
PRK00742       5 VLVVDDSAFMRRLLsEILNSDPDIEVVGTARDGLEAVEKIKKLNPDVITLDVEMPVMDGIEALRKIMALRP---TPVVMV 81

                         90       100
                 ....*....|....*....|....*..
gi 117929306  97 TADLTR--DAVHRALDLGARDFLTKPF 121
PRK00742      82 SSLTERgaEITLEALELGAVDFVPKPF 108

-1

34367

COG4753

Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]

Response regulator containing CheY-like receiver domain and AraC-type DNA-binding...

false

true

false

475

1e-15

79.20

22.95

4,17,3,21,38,26,45,88,71,4,92,78,34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRS--GLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRsledaEYLP--- 92
COG4753        4 VLIVDDEPLIREGLKSLIDWEalGIEVVGTAANGKEALELIQETQPDIVITDINMPGMDGLDLIKAIK-----EQSPdte 78

                         90       100       110
                 ....*....|....*....|....*....|....
gi 117929306  93 ILVLTADLTRDAVHRALDLGARDFLTKPFDATEV 126
COG4753       79 FIILSGYDEFEYAKKAMKLGVKDYLLKPVDKAEL 112

-1

130454

TIGR01387

cztR_silR_copR

heavy metal response regulator

false

true

false

218

2e-15

78.30

52.29

5,17,0,24,42,24,41,85,65,13,98,79,7,106,86,28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRslEDAEYLPILVLT 97
TIGR01387      1 ILVVEDEQKTAEYLQQGLSESGYV-VDAASNGRDGLHLALKDDYDLIILDVMLPGMDGWQILQTLR--RSGKQTPVLFLT 77

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 117929306  98 A-DLTRDAVhRALDLGARDFLTKPFDATEVVLRVRNLL 134
TIGR01387     78 ArDSVADKV-KGLDLGADDYLVKPFSFSELLARVRTLL 114

-1

137979

PRK10551

hypothetical protein; Provisional

false

true

false

518

4e-15

77.79

43.05

8,187,279,25,212,305,2,214,308,19,233,332,8,242,340,27,271,367,7,278,382,20,299,402,100

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 188 VFQPIIRLADTEVVGFEALSRFADP-AG-TPPDRWFSEASSVGLGPDL-----ELKAMHTAlQYLPTIPDGVFLALNASP 260
PRK10551     280 VYQPVVDTQTLRVTGLEVLLRWRHPtAGeIPPDAFINYAEAQKLIVPLtqhlfELIARDAA-ELQKVLPVGAKLGINIAP 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 261 ELVLSRKLEnlQDVSSLD--------RLVLELTEHAAVEDYGVIQErLAPFREKGMRVAIDDTGAGFASLRHILLLQPEI 332
PRK10551     359 AHLHSDSFK--ADVQRLLaslpadhfQIVLEITERDMLQEEEALKL-FAWLHSQGIEIAIDDFGTGHSALIYLERFTLDY 435

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117929306 333 IKLDISITRSIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAP 399
PRK10551     436 LKIDRGFINAIGTETVTSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLREHGVNFLQGYWISRPLP 502

-1

139064

PRK12555

chemotaxis-specific methylesterase; Provisional

false

true

false

340

2e-14

75.04

30.29

4,17,3,14,31,18,56,90,74,14,104,90,16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLL-EALLTRSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDaeyLPILVL 96
PRK12555       4 VGIVDDSALAREALrRIIARRPDHRVLGVATDGLQARDLCKAQPPDVVLLDLEMPRMDGLTFLRRIMRRRP---CPVLIV 80

                         90       100
                 ....*....|....*....|....*.
gi 117929306  97 TADLTRDA--VHRALDLGARDFLTKP 120
PRK12555      81 SSLTEAGAsiTYEALGAGALDAVDKP 106

-1

130877

TIGR01818

ntrC

nitrogen regulation protein NR(I)

false

true

false

463

3e-14

74.77

23.11

3,17,0,24,42,24,46,90,70,37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAeyLPILVLT 97
TIGR01818      1 VWVVDDDRSIRWVLEKALSRAGYE-VRTFGNAASVLRALARGQPDLLITDVRMPGEDGLDLLPQIKKRHPQ--LPVIVMT 77

                         90       100       110
                 ....*....|....*....|....*....|
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFDATEVV 127
TIGR01818     78 AHSDLDTAVAAYQRGAFEYLPKPFDLDEAV 107

-1

32379

COG2197

CitB

Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]

Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain...

false

true

false

211

3e-14

74.61

55.45

3,16,1,27,43,29,40,85,69,49

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  17 HVLVVDDNEANVQLLEALLTRSGLRHV-ATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRslEDAEYLPILV 95
COG2197        2 KVLIVDDHPLVREGLRQLLELEPDLEVvGEASNGEEALDLARELKPDVVLLDLSMPGMDGLEALKQLR--ARGPDIKVVV 79

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 117929306  96 LTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLL 134
COG2197       80 LTAHDDPAYVIRALRAGADGYLLKDASPEELVEAIRAVA 118

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

4e-14

74.36

19.80

7,189,882,18,207,901,7,214,910,34,248,946,11,259,962,14,274,976,3,277,981,122

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  190 QPIIRLADTEVVGFEALS-RFADPAG--TPPDRWFSEASSVGLGPDLELKAMHTALQYLPTI--PDGVFLALNAS----- 259
PRK09776      883 QEIASPRIPEARNLWLISlRLWDCEGeiIDEGAFRPAAEDPALMHALDRWVIHELFQQGARAvaSKGLSIAIPLSvasls 962

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  260 PELVLSRKLENLQDvSSL--DRLVLELTEHAAVEDYGVIQERLAPFREKGMRVAIDDTGAGFASLRHILLLQPEIIKLDI 337
PRK09776      963 SATLLPFLLEQLEN-SPLppRLLHLEITETALLNHAEAASRLVQKLRLAGCRVVLDDFGRGLSSFNYLKAFMADYLKIDG 1041

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 117929306  338 SITRSIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAP 399
PRK09776     1042 ELCANLQGNLMDEMLVSIINGIAQRLGMKTIAGPVELPLTLDTLSGIGVDLAQGYVIGRPQP 1103

-1

34203

COG4565

CitB

Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]

Response regulator of citrate/malate metabolism [Transcription / Signal transduction...

false

true

false

224

1e-13

72.94

61.16

5,16,1,8,24,13,10,37,23,47,88,70,4,92,76,62

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  17 HVLVVDDN----EANVQLLEALltrSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSledaEYLP 92
COG4565        2 NVLIIEDDpmvaEIHRRYVKQI---PGFSVVGTAGTLEEAKMIIEEFKPDLILLDIYMPDGNGIELLPELRS----QHYP 74

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117929306  93 --ILVLTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLLETRALYRTLRAHNIALSDEL 154
COG4565       75 vdVIVITAASDMETIKEALRYGVVDYLIKPFTFERLQQALTRYRQKRHALESHQQLSQKELDQL 138

-1

32383

COG2201

CheB

Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain [Cell motility and secretion / Signal transduction mechanisms]

Chemotaxis response regulator containing a CheY-like receiver domain and a...

false

true

false

350

3e-13

71.47

30.00

4,17,3,22,39,26,48,90,74,12,102,88,20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSG-LRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDaeyLPILVL 96
COG2201        4 VLVVDDSALMRKVISDILNSDPdIEVVGTARNGREAIDKVKKLKPDVITLDVEMPVMDGLEALRKIMRLRP---LPVIMV 80

                         90       100
                 ....*....|....*....|....*...
gi 117929306  97 TADLTR--DAVHRALDLGARDFLTKPFD 122
COG2201       81 SSLTEEgaEATLEALELGAVDFIAKPSG 108

-1

138409

PRK11107

hybrid sensory histidine kinase BarA; Provisional

false

true

false

920

3e-13

71.46

11.85

3,17,670,18,36,688,86,124,774,5

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLtRSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAEYLPILVLT 97
PRK11107     671 VMAVDDNPANLKLIGALL-EEQVEHVVLCDSGHQAVELAKQRPFDLIFMDIQMPGMDGIRACELIRQLPHNQNTPIIAVT 749

                         90       100       110
                 ....*....|....*....|....*....|..
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFDatEVVLR 129
PRK11107     750 AHAMAGERERLLGAGMDDYLAKPID--EAALK 779

-1

138212

PRK10841

hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional

false

true

false

947

1e-12

69.69

12.46

4,6,815,35,42,850,41,85,891,35,122,926,7

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306   7 SGALERFSDAHVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRslE 86
PRK10841     816 DKAVDDNDDMMILVVDDHPINRRLLADQLGSLGYQ-CKTANDGVDALNVLSKNHIDIVLSDVNMPNMDGYRLTQRIR--Q 892

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 117929306  87 DAEYLPILVLTADLTRDAVHRALDLGARDFLTKPfdATEVVLR 129
PRK10841     893 LGLTLPVIGVTANALAEEKQRCLEAGMDSCLSKP--VTLDVLK 933

-1

138104

PRK10710

DNA-binding transcriptional regulator BaeR; Provisional

false

true

false

240

1e-12

69.39

47.08

3,17,12,23,41,35,46,90,81,44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLrHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDaeyLPILVLT 97
PRK10710      13 ILIVEDEPKLGQLLIDYLRAASY-APTLISHGDEVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSD---IPIVMVT 88

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLL 134
PRK10710      89 AKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTIL 125

-1

138305

PRK10955

DNA-binding transcriptional regulator CpxR; Provisional

false

true

false

232

2e-12

69.09

48.28

4,17,3,23,41,26,17,59,43,25,87,68,47

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLrHVATARDGDEALRMVRDfQPDLILLDLRMPKLDGYTVLERLRSledAEYLPILVLT 97
PRK10955       4 ILLVDDDRELTSLLKELLEMEGF-NVIVAHDGEQALDLLDD-SIDLLLLDVMMPKKNGIDTLKALRQ---THQTPVIMLT 78

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLL 134
PRK10955      79 ARGSELDRVLGLELGADDYLPKPFNDRELVARIRAIL 115

-1

138091

PRK10693

response regulator of RpoS; Provisional

false

true

false

337

2e-12

68.96

29.97

3,16,8,25,42,33,42,86,75,34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  17 HVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSleDAEYLPILVL 96
PRK10693       9 QILIVEDEPVFRSLLDSWFSSLGAT-TVLAADGVDALELLGGFTPDLMICDIAMPRMNGLKFVEHLRN--RGDQTPVLVI 85

                         90       100
                 ....*....|....*....|....
gi 117929306  97 TADLTRDAVHRALDLGARDFLTKP 120
PRK10693      86 SATENMADIAKALRLGVEDVLLKP 109

-1

138397

PRK11091

aerobic respiration control sensor protein ArcB; Provisional

false

true

false

779

2e-12

68.48

13.22

4,16,526,23,40,549,55,95,605,9,105,614,15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  17 HVLVVDDNEANVQLLEALLTRSGlRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAEYLPILV- 95
PRK11091     527 NILLVEDIELNVIVARSLLEKLG-NSVDVAMTGKDALEMFKPGEYDLVLLDIQLPDMTGLDVARELRERYGREDLPPLVa 605

                         90       100
                 ....*....|....*....|....*
gi 117929306  96 LTADLTRDAvHRALDLGARDFLTKP 120
PRK11091     606 LTANVLKDK-QEYLDAGMDDVLSKP 629

-1

138282

PRK10923

glnG

nitrogen regulation protein NR(I); Provisional

false

true

false

469

2e-12

68.41

22.81

3,17,5,23,41,28,42,85,70,42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLrHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRslEDAEYLPILVLT 97
PRK10923       6 VWVVDDDSSIRWVLERALAGAGL-TCTTFENGNEVLEALASKTPDVLLSDIRMPGMDGLALLKQIK--QRHPMLPVIIMT 82

                         90       100       110
                 ....*....|....*....|....*....|
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFDATEVV 127
PRK10923      83 AHSDLDAAVSAYQQGAFDYLPKPFDIDEAV 112

-1

138611

PRK11517

transcriptional regulatory protein YedW; Provisional

false

true

false

223

3e-12

68.42

58.30

6,17,2,24,42,26,42,87,68,11,101,79,5,106,87,25,131,113,19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSledAEYLPILVLT 97
PRK11517       3 ILLIEDNQRTQEWVTQGLSEAGYV-IDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQILQTLRT---AKQTPVICLT 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 117929306  98 AdltRDAVH---RALDLGARDFLTKPFDATEVVLRVR-NLLETRALYRTLRAHNIAL 150
PRK11517      79 A---RDSVDdrvRGLDSGANDYLVKPFSFSELLARVRaQLRQHHALNSTLEISGLRM 132

-1

138768

PRK11829

biofilm formation regulator HmsP; Provisional

false

true

false

728

3e-12

68.19

31.18

7,184,486,31,215,519,33,248,553,29,277,590,46,323,639,25,352,664,11,363,676,37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 185 LTTVFQPIIRLADTEVVGFEALSRFADPAGT--PPDRWFSEASSVGLGPDLELKAMHTALQYLPTI-PDGVFLALNASPE 261
PRK11829     487 FTLFLQPQWDMKRQQVIGAEALLRWCQPDGSyvLPSGFVHFAEEEGMMVPLGNWVLEEACRILADWkARGVSLPLSVNIS 566

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 262 LVLSRKLENLQDVSSL--------DRLVLELTEHAAVEDYGVIQERLAPFREKGMRVAIDDTGAGFASLR---HILLLQP 330
PRK11829     567 GLQVQNKQFLPHLKTLishyhidpQQLLLEITETAQIQDLDEALRLLRELQGLGLLIALDDFGIGYSSLRylnHLKSLPI 646

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117929306 331 EIIKLDISITRSIDRDPArralASALVSFAADV-GAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAPR 400
PRK11829     647 HMIKLDKSFVKNLPEDDA----IARIISCVSDVlKVRVMAEGVETEEQRQWLLEHGIQCGQGFLFSPPLPR 713

-1

132001

TIGR02956

TMAO_torS

TMAO reductase sytem sensor TorS

false

true

false

968

4e-12

67.50

10.85

3,15,702,24,40,726,48,88,775,32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  16 AHVLVVDDNEANVQLLEALLTRSGlRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDA-EYLPIL 94
TIGR02956    703 QRVLLVEDNEVNQMVAQGFLTRLG-HKVTLAESGQSALECFHQHAFDLALLDINLPDGDGVTLLQQLRAIYGAkNEVKFI 781

                         90       100
                 ....*....|....*....|....*.
gi 117929306  95 VLTADLTRDAVHRALDLGARDFLTKP 120
TIGR02956    782 AFSAHVFNEDVAQYLAAGFDGFLAKP 807

-1

137310

PRK09468

ompR

osmolarity response regulator; Provisional

false

true

false

239

5e-12

67.33

49.79

5,16,6,25,42,31,46,90,77,8,100,85,7,107,94,31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  17 HVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAeyLPILVL 96
PRK09468       7 KILVVDDDMRLRALLERYLTEQGFQ-VRSAANAEQMDRLLTRESFHLMVLDLMLPGEDGLSICRRLRSQNNP--TPIIML 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 117929306  97 TAdlTRDAVHR--ALDLGARDFLTKPFDATEVVLRVRNLLETRA 138
PRK09468      84 TA--KGEEVDRivGLEMGADDYLPKPFNPRELLARIRAVLRRQA 125

-1

137400

PRK09581

pleD

response regulator PleD; Reviewed

false

true

false

457

9e-12

66.48

26.04

2,10,150,28,40,178,91

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  11 ERFSDAHVLVVDDNEANVQLLEALLTRSglRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAEY 90
PRK09581     151 NKIEDGRILLVDDDVSQAERIANILKEE--FRVDVLSDPEEALIRAAEGNYDLIIVSASFENYDPLRLCSQLRSKERTRY 228

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 117929306  91 LPILVLTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVR 131
PRK09581     229 VPILLLVDEDEDPRLVKALELGVNDYLMRPIDKNELLARVR 269

-1

137850

PRK10365

transcriptional regulatory protein ZraR; Provisional

false

true

false

441

1e-11

65.82

23.13

3,17,7,23,41,30,47,90,77,32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLrHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAeyLPILVLT 97
PRK10365       8 ILVVDDDISHCTILQALLRGWGY-NVALANSGRQALEQVREQVFDLVLCDVRMAEMDGIATLKEIKALNPA--IPVLIMT 84

                         90       100
                 ....*....|....*....|....*
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFD 122
PRK10365      85 AYSSVETAVEALKTGALDYLIKPLD 109

-1

138195

PRK10816

DNA-binding transcriptional regulator PhoP; Provisional

false

true

false

223

4e-11

64.46

51.12

3,17,2,22,40,24,46,88,70,46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGlRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEdaEYLPILVLT 97
PRK10816       3 VLVVEDNALLRHHLKVQLQDAG-HQVDAAEDAKEADYYLNEHLPDIAIVDLGLPDEDGLSLIRRWRSND--VSLPILVLT 79

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLL 134
PRK10816      80 ARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALM 116

-1

139916

PRK13856

two-component response regulator VirG; Provisional

false

true

false

241

5e-11

64.07

49.38

4,16,2,25,42,27,33,78,60,29,107,90,31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  17 HVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGytvLERLRSLEDAEYLPILVL 96
PRK13856       3 HVLVIDDDVAMRHLIVEYLTIHAFK-VTAVADSQQFNRVLSSETVDVVVVDLNLGREDG---LEIVRSLATKSDVPIIII 78

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 117929306  97 TADLTRDAVHR-ALDLGARDFLTKPFDATEVVLRVRNLLETRA 138
PRK13856      79 SGDRLEEADKVvALELGATDFIAKPFGTREFLARIRVALRVRP 121

-1

138376

PRK11059

regulatory protein CsrD; Provisional

false

true

false

642

6e-11

63.75

34.11

6,189,421,4,194,425,21,215,448,38,253,487,13,266,506,11,277,518,122

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 190 QPIIrLADTEVVGFEALSRFADPAGT--PPDRWFSEASSVGLGPDLELKAMHTALQYLPTIPDGVF-LALNASPELVLSR 266
PRK11059     422 QPVV-TRDGQVHHRELMCRIRDGQGNevRAAEFMPMVLQCGLSEQYDRQVIERVLPLLSYWPEESQnLSINLSVDSLLSR 500

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 267 ------KLENLQDVSSL-DRLVLELTEHAAVEDYGVIQERLAPFREKGMRVAIDDTGAGFASLRHILLLQPEIIKLDISI 339
PRK11059     501 afqrwlRDTLLQCERSQrKRLIFELAEADVVQHIDRLRPVLRMLRGLGCRLAVDQAGLTVVSTSYIKELNVELIKLHPSL 580

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 340 TRSIDRDPARRALASALVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRPAP 399
PRK11059     581 VRNIHQRTENQLFVRSLVGACAGTETQVFAEGVESREEWQTLQILGVSGGQGDFFASPQP 640

-1

33502

COG3707

AmiR

Response regulator with putative antiterminator output domain [Signal transduction mechanisms]

Response regulator with putative antiterminator output domain [Signal transduction...

false

true

false

194

7e-11

63.34

73.71

2,12,2,62,77,64,81

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  13 FSDAHVLVVDDNEANVQLLEALLTRSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDgytVLERLRSLEDAEYLP 92
COG3707        3 AMLLRVLVADDEALTRMDIREGLLEAGYQRVGEAADGLEAVEVCERLQPDVVILDIEMPRRD---IIEALLLASENVARP 79

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117929306  93 ILVLTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLLETRALYRTLRAHNIALSDELEKRR 158
COG3707       80 IVALTAYSDPALIEAAIEAGVMAYIVKPLDESRLLPILDVAVSRFEERRALRRELAKLKDRLEERK 145

-1

34204

COG4566

TtrR

Response regulator [Signal transduction mechanisms]

false

true

false

202

1e-10

62.57

70.79

4,17,6,24,42,30,41,85,71,56,141,130,19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRslEDAEYLPILVLT 97
COG4566        7 VHVVDDDESVRDALAFLLESAGFQ-VKCFASAEEFLAAAPLDRPGCLLLDVRMPGMSGLELQDRLA--ERGIRLPVIFLT 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLLETRALYR---TLRAHNIALSDELEKRRAQ 160
COG4566       84 GHGDIPMAVQAMKAGAVDFLEKPFSEQDLLDAVERALARDASRRaeaDRQAAIRARLATLTPRERQ 149

-1

138153

PRK10766

DNA-binding transcriptional regulator TorR; Provisional

false

true

false

224

5e-10

60.44

50.89

4,16,3,25,42,28,48,92,76,13,106,89,28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  17 HVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAEYlpILVL 96
PRK10766       4 HILVVEDEPVTRARLQGYFEQEGYR-VSEAASGAGMREIMQNQHVDLILLDINLPGEDGLMLTRELRSRSTVGI--ILVT 80

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 117929306  97 TADLTRDAVhRALDLGARDFLTKPFDATEVVLRVRNLL 134
PRK10766      81 GRTDSIDRI-VGLEMGADDYVTKPFELRELLVRVKNLL 117

-1

137546

PRK09836

DNA-binding transcriptional activator CusR; Provisional

false

true

false

226

5e-10

60.42

50.44

3,17,2,24,42,26,46,90,72,44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAeyLPILVLT 97
PRK09836       3 LLIVEDEKKTGEYLTKGLTEAGFV-VDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWDIVRMLRSANKG--MPILLLT 79

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLL 134
PRK09836      80 ALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLL 116

-1

104359

PRK10161

transcriptional regulator PhoB; Provisional

false

true

false

229

7e-10

60.12

50.66

2,17,4,27,45,31,89

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLRHVAtARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAEYLPILVLT 97
PRK10161       5 ILVVEDEAPIREMVCFVLEQNGFQPVE-AEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLT 83

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 117929306  98 ADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLL 134
PRK10161      84 ARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVM 120

-1

138051

PRK10643

DNA-binding transcriptional regulator BasR; Provisional

false

true

false

222

8e-10

60.11

51.35

6,17,2,22,39,26,17,59,43,24,85,67,13,101,80,5,106,88,28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSG--LRHVATARDGDEALRMVrdfQPDLILLDLRMPKLDGYTVLERLRslEDAEYLPILV 95
PRK10643       3 ILIVEDDTLLLQGLILAAQTEGyaCDGVSTAREAEQSLESG---HYSLVVLDLGLPDEDGLHFLARIR--QKKYTLPVLI 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 117929306  96 LTAdltRDAVH---RALDLGARDFLTKPFDATEVVLRVRNLL 134
PRK10643      78 LTA---RDTLEdriAGLDVGADDYLVKPFALEELHARIRALL 116

-1

33728

COG3947

Response regulator containing CheY-like receiver and SARP domains [Signal transduction mechanisms]

Response regulator containing CheY-like receiver and SARP domains [Signal transduction...

false

true

false

361

2e-09

58.83

27.42

4,17,2,22,40,24,48,90,72,17,109,89,12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGlRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAeyLPILVLT 97
COG3947        3 IIIVDDDAAIVKLLSVILSRAG-HEVRSCSHPVEALDLLEVFKPDLIFLDIVMPYMNGIEFAEQVRDIESA--VPIIFIS 79

                         90       100
                 ....*....|....*....|....
gi 117929306  98 ADLTRDAVHRalDLGARDFLTKPF 121
COG3947       80 SHAEYADDSF--GMNLDDYLPKPV 101

-1

138391

PRK11083

DNA-binding response regulator CreB; Provisional

false

true

false

229

2e-09

58.84

50.66

5,15,3,32,48,35,40,90,75,8,100,83,7,107,92,27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  16 AHVLVVDDNEANVQLLEALLTRSGLRHVATARdGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAeyLPILV 95
PRK11083       4 PTILLVEDEQAIADTLVYALQSEGFTVEWFER-GLPALDKLRQQPPDLVILDVGLPDISGFELCRQLRAFHPA--LPVIF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 117929306  96 LTAdlTRDAVHR--ALDLGARDFLTKPFDATEVVLRVRNLL 134
PRK11083      81 LTA--RSDEVDRlvGLEIGADDYVAKPFSPREVAARVRTIL 119

-1

137960

PRK10529

DNA-binding transcriptional activator KdpE; Provisional

false

true

false

225

3e-09

58.32

49.78

3,15,1,26,42,27,33,78,60,53

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  16 AHVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGytvLERLRSLEDAEYLPILV 95
PRK10529       2 TNVLIVEDEQAIRRFLRTALEGDGMR-VFEAETLQRGLLEAATRKPDLIILDLGLPDGDG---IEFIRDLRQWSAIPVIV 77

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 117929306  96 LTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVR 131
PRK10529      78 LSARSEESDKIAALDAGADDYLSKPFGIGELQARLR 113

-1

137244

PRK09390

fixJ

response regulator FixJ; Provisional

false

true

false

202

4e-08

54.26

52.48

7,13,1,27,40,30,17,60,47,23,85,70,12,97,84,5,103,89,2,106,91,16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  14 SDAHVLVVDDNEANVQLLEALLTRSGL--RHVATARDGDEALRMVRdfqPDLILLDLRMPKLDGYTVLERLRslEDAEYL 91
PRK09390       2 TKGVVHVVDDDEAMRDSLAFLLDSAGFevRLFESAQAFLDALPGLR---FGCVVTDVRMPGIDGIELLRRLK--ARGSPL 76

                         90       100       110
                 ....*....|....*....|....*....|...
gi 117929306  92 PILVLT--ADLTRdAVhRALDLGARDFLTKPFD 122
PRK09390      77 PVIVMTghGDVPL-AV-EAMKLGAIDFIEKPFE 107

-1

131961

TIGR02915

PEP_resp_reg

putative PEP-CTERM system response regulator

false

true

false

445

5e-08

53.98

29.21

6,17,0,21,41,21,31,73,52,14,87,70,44,140,114,8,152,122,8

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSglrHVATARDGDEALRMVRDFQPDLILLDLRMPKlDGYTVLERLRSLED----AEYLPI 93
TIGR02915      1 LLIVEDDLGLQKQLKWSFADY---ELAVAADRESAIALVRRHEPAVVTLDLGLPP-DADGASEGLAALQQilaiAPDTKV 76

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117929306  94 LVLTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRnlletralyRTLRAHNIalsdELEKRRAQ 160
TIGR02915     77 IVITGNDDRENAVKAIGLGAYDFYQKPIDPDVLKLIVD---------RAFHLYTL----ETENRRLQ 130

-1

33090

COG3279

LytT

Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]

Response regulator of the LytR/AlgR family [Transcription / Signal transduction...

false

true

false

244

6e-08

53.82

48.77

4,17,3,18,35,22,51,88,73,16,106,89,33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALL-TRSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEdaEYLPILVL 96
COG3279        4 VLIVDDEPLAREELRRILnEIPDIEIVGEAENGEEALQLLQGLRPDLVFLDIAMPDINGIELAARIRKGD--PRPAIVFV 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 117929306  97 TADLTRDAvhRALDLGARDFLTKPFDATEVVLRVRNLLETRAL 139
COG3279       82 TAHDEYAV--AAFEVEALDYLLKPISEERLAKTLERLRRYAQL 122

-1

138058

PRK10651

transcriptional regulator NarL; Provisional

false

true

false

216

1e-07

52.76

47.69

4,15,6,9,24,19,8,35,27,48,85,75,34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  16 AHVLVVDDN----EANVQLLEallTRSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRslEDAEYL 91
PRK10651       7 ATILLIDDHpmlrTGVKQLIS---MAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMNGLETLDKLR--EKSLSG 81

                         90       100
                 ....*....|....*....|....*...
gi 117929306  92 PILVLTADLTRDAVHRALDLGARDFLTK 119
PRK10651      82 RIVVFSVSNHEEDVVTALKRGADGYLLK 109

-1

138454

PRK11173

two-component response regulator; Provisional

false

true

false

237

1e-07

52.76

48.10

6,16,4,24,41,28,34,78,62,20,101,82,2,103,85,8,111,95,23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  17 HVLVVDDNEANVQLLEALLTRSGLrHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGytvLERLRSLEDAEYLPILVL 96
PRK11173       5 HILIVEDELVTRNTLKSIFEAEGY-DVFEATDGAEMHQILSENDINLVIMDINLPGKNG---LLLARELREQANVALMFL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 117929306  97 TAdltRD-AVHRALDL--GARDFLTKPFDATEVVLRVRNLL 134
PRK11173      81 TG---RDnEVDKILGLeiGADDYITKPFNPRELTIRARNLL 118

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

3e-07

51.46

25.98

3,27,0,9,37,9,49,90,58,55

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  28 VQLLEALLTrSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEdaeyLPILVLTADLTRDAVHR 107
COG3706        1 VKLLEAKLP-LEYKEVATAKKGLIALAILLDHKPDYKLLDVMMPGMDGFELCRRLKAEP----ATVVMVTALDDSAPRVR 75

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 117929306 108 ALDLGARDFLTKPFDATEVVLRVRNLLETRALYRTLRA 145
COG3706       76 GLKAGADDFLTKPVNDSQLFLRAKSLVRLKCSIDELRL 113

-1

137598

PRK09935

transcriptional regulator FimZ; Provisional

false

true

false

210

3e-07

51.43

56.19

3,15,3,22,37,26,49,88,75,46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  16 AHVLVVDDNEANVQLLEALLTR-SGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEdaEYLPIL 94
PRK09935       4 ASVIIMDEHPIVRMSIEVLLQKnSNIQVVLKTDDSRITIDYLRTYPVDLVILDIELPGTDGFTLLKRIKQIQ--ETVKVL 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 117929306  95 VLTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVRNLL 134
PRK09935      82 FLSSKSECFYAGRAIRAGANGFVSKRKDLNDIYNAVQMIL 121

-1

33240

COG3434

Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]

Predicted signal transduction protein containing EAL and modified HD-GYP domains [...

false

true

false

407

3e-07

51.43

45.70

7,189,7,5,195,12,31,233,43,38,275,81,20,297,101,40,340,141,11,356,152,41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 190 QPIIRlADTEVVGFEALSRFADPAGTPPDRWFSEASSvglgpdlELKAMHTALQYLPTIPDGVFLALNASPELVLSRKLE 269
COG3434        8 QPILD-RNKEVFGYELLFREGEKNKYPEDVDNSRATY-------RIIIEEFVIQGIDKLANGKKCFINFPEELLISDLPE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306 270 NLqdvsSLDRLVLELTEHAAVEDYGViqERLAPFREKGMRVAIDDTGAGFASLRHILLLQPEIIKLDIsitRSIDRDPAR 349
COG3434       80 LL----PPDKVVIEILEDCPPTEKLL--SAIKELKQKGYLLALDDFIFSNVSEWKPLLPLSDIVKIDF---KRVTFDKAR 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 117929306 350 RAlasalVSFAADVGAHLIAEGVETAAELQTLVKLGVEWAQGYHLGRP 397
COG3434      151 LF-----DRDLGYINKKFLAEKVETEEEFEQAKKAGFDLFQGYFFSKP 193

-1

34205

COG4567

Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain [Signal transduction mechanisms / Transcription]

Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain [..

false

true

false

182

4e-07

50.73

76.92

4,14,8,27,42,35,46,90,81,36,129,117,31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  15 DAHVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAeyLPIL 94
COG4567        9 DKSLLLVDDDTPFLRTLARAMERRGFA-VVTAESVEEALAAARTAPPAYAVVDLKLGDGSGLAVIEALRERRAD--MRIV 85

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117929306  95 VLTADLTRDAVHRALDLGARDFLTKPFDATEVvlrVRNLLETRALYRTLRAHNIALSDELEKRRAQ 160
COG4567       86 VLTGYASIATAVEAVKLGACDYLAKPADADDI---LAALLRREPDEDTAPPENPMSADRLRWEHIQ 148

-1

137612

PRK09959

hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional

false

true

false

1197

5e-07

50.50

8.44

3,17,960,23,41,983,42,85,1025,36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306   18 VLVVDDNEANVQLLEALLTRSGLrHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRslEDAEYLPILVLT 97
PRK09959      961 ILIADDHPTNRLLLKRQLNLLGY-DVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFELTRKLR--EQNSSLPIWGLT 1037

                          90       100
                  ....*....|....*....|....
gi 117929306   98 ADLTRDAVHRALDLGARDFLTKPF 121
PRK09959     1038 ANAQANEREKGLNCGMNLCLFKPL 1061

-1

137869

PRK10403

transcriptional regulator NarP; Provisional

false

true

false

215

1e-06

49.47

47.44

3,16,7,19,35,27,48,85,75,34

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  17 HVLVVDDNEANVQLLEALL-TRSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRslEDAEYLPILV 95
PRK10403       8 QVLIVDDHPLMRRGVRQLLeLDPGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGLDTLNALR--RDGVTAQIII 85

                         90       100
                 ....*....|....*....|....
gi 117929306  96 LTADLTRDAVHRALDLGARDFLTK 119
PRK10403      86 LTVSDASSDIFALIDAGADGYLLK 109

-1

138099

PRK10701

DNA-binding transcriptional regulator RstA; Provisional

false

true

false

240

2e-06

48.56

40.42

6,17,4,10,28,14,19,48,33,40,91,73,7,99,80,7,106,88,13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANvQLLEALLTRSGLRHVATARdGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAeylPILVLT 97
PRK10701       5 VFVEDDAEVG-SLIAAYLAKHDIDVTVEPR-GDRAEETILREQPDLVLLDIMLPGKDGMTICRDLRPKWSG---PIVLLT 79

                         90       100
                 ....*....|....*....|...
gi 117929306  98 AdLTRDAVH-RALDLGARDFLTK 119
PRK10701      80 S-LDSDMNHiLALEMGACDYILK 101

-1

137827

PRK10336

DNA-binding transcriptional regulator QseB; Provisional

false

true

false

219

2e-06

48.78

52.05

6,17,2,24,41,28,15,59,43,24,85,67,13,101,80,6,107,89,27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSGLR--HVATARDGDEALRMVrdfQPDLILLDLRMPKLDGYTVLERLRslEDAEYLPILV 95
PRK10336       3 ILLIEDDMLIGDGIKTGLSKMGFSvdWFTQGRQGKEALYSA---PYDAVILDLTLPGMDGRDILREWR--EKGQREPVLI 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 117929306  96 LTAdltRDAVHR---ALDLGARDFLTKPFDATEVVLRVRNLL 134
PRK10336      78 LTA---RDALAErveGLRLGADDYLCKPFALIEVAARLEALM 116

-1

137611

PRK09958

DNA-binding transcriptional activator EvgA; Provisional

false

true

false

204

7e-06

46.81

48.53

2,18,3,72,92,75,27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  19 LVVDDNEANVQLLEALLTRSGLRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLERLRSLEDAEYlpILVLTA 98
PRK09958       4 IIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQVLETLRKRQYSGI--IIIVSA 81

                         90       100
                 ....*....|....*....|.
gi 117929306  99 DLTRDAVHRALDLGARDFLTK 119
PRK09958      82 KNDHFYGKHCADAGANGFVSK 102

-1

137324

PRK09483

response regulator; Provisional

false

true

false

216

8e-06

46.64

52.31

5,17,3,8,34,11,8,42,29,39,81,69,8,92,77,39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEanvqllealLTRSGLRH----------VATARDGDEALRMVRDFQPDLILLDLRMPKLDGYTVLER-LRSLE 86
PRK09483       4 VLLVDDHE---------LVRAGIRRiledikgikvVGEASCGEDAVKWCRTNAVDVVLMDMNMPGIGGLEATRKiLRSTP 74

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 117929306  87 DAEylpILVLTADLTRDAVHRALDLGARDFLTKPFDATEVVLRVR 131
PRK09483      75 DVK---IIMLTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIR 116

-1

138717

PRK11697

putative two-component response-regulatory protein YehT; Provisional

false

true

false

239

9e-06

46.41

42.68

8,17,3,22,39,26,36,78,62,2,81,64,11,92,76,6,101,82,2,103,86,2,106,88,17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTRSG-LRHVATARDGDEALRMVRDFQPDLILLDLRMPKLDGytvLErLRSLEDAEYLP-ILV 95
PRK11697       4 VLIVDDEPLAREELRELLQEEGdIEIVGECSNAIEALGAIHRLKPDVVFLDIQMPRISG---LE-LVGMLDPEHMPyIVF 79

                         90       100       110
                 ....*....|....*....|....*....|
gi 117929306  96 LTAdltRD--AVhRALDLGARDFLTKPFDA 123
PRK11697      80 VTA---FDeyAI-KAFEEHAFDYLLKPIDP 105

-1

137892

PRK10430

DNA-binding transcriptional activator DcuR; Provisional

false

true

false

239

3e-05

44.74

54.39

6,17,3,20,37,24,24,61,50,40,103,90,21,124,113,4,128,121,12

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306  18 VLVVDDNEANVQLLEALLTR-SGLRHVATARDGDEALRMVRDFQP--DLILLDLRMPKLDGYTVLERLRSLEDAEYLPIL 94
PRK10430       4 VLIVDDDAMVAELNRRYVAQiPGFQCCGTASTLEKAKEIIFNSDTpiDLILLDIYMQQENGLDLLPVLHEAGCKSDVIVI 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 117929306  95 VLTADLTrdAVHRALDLGARDFLTKPFDAT--EVVL----RVRNLLETRALY 140
PRK10430      84 SSAADAA--TIKDSLHYGVVDYLIKPFQASrfEEALtgwrQKKMALEKRQYY 133

-1

139663

PRK13557

histidine kinase; Provisional

false

true

false

538

4e-04

40.86

23.42

8,8,406,33,42,439,16,58,456,13,71,470,17,90,487,4,95,491,13,109,504,7,116,513,19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117929306   9 ALERFSDAHVLVVDDNEANVQLLEALLTRSGLRhVATARDGDEALRMVRD-FQPDLILLDLRMP-KLDGYTVLERLRSLE 86
PRK13557     407 AIDRGGTETILIVDDRPDVAELARMILEDFGYR-TLVASNGREALEILEShPEVDLLFTDLIMPgGMNGVMLAREARRRQ 485

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 117929306  87 DAeyLPILvLTADLTRDAVHRAlDLGARDF--LTKPFDATEVVLRVRNLLE 135
PRK13557     486 PK--IKVL-LTTGYAEASIERT-DVGGSEFdiVNKPYRRAELARRVRMVLD 532

-1

active site	0	8	8	true	29071	cd00156	REC
phosphorylation site	1	1	1	true	29071	cd00156	REC
intermolecular recognition site	2	5	5	true	29071	cd00156	REC
dimerization interface	3	3	3	true	29071	cd00156	REC