NCBI Conserved Domain Search

NewSearch

CDD Home

Conserved domains on [gi\|117928869\|ref\|YP_873420.1\|]
diguanylate cyclase/phosphodiesterase [Acidothermus cellulolyticus 11B]

Graphical summary show options »	Show site features Horizontal zoom: ×	?



List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH

of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

30163

cd01948

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

true

false

true

240

8e-65

242.81

100.00

2,194,0,77,271,79,161

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 195 SEFRRAVTDNQLVLHYQPKAKLSDGAVEAIEALVRWHHPARGLLYPDVFVPLVEQTDLIDDLTRWVLRHALEDLATI--G 272
cd01948        1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWqaG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 273 DPHLAVAVNISARNLSRHTFAADVKAAVRRAGIEPHRLVLELTETALLFDPTRAHDVFTDLTSYGIRVSIDDFGRGQTSL 352
cd01948       81 GPDLRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYSSL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 353 GYLSALPLSEIKIDRTFVRDMVTNAAHAAIVRSVVELGHNLGLIVVAEGVETAEVGDELRECGCDVAQGYWFARPMPLVD 432
cd01948      161 SYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAEE 240

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

133472

cd01949

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as domain of unknown function 1 (DUF1). It is widely present in bacteria and often links to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain has been suggested to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesiveness in bacteria.

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

true

false

true

157

5e-37

150.82

96.18

3,17,0,25,48,25,64,112,91,60

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  18 HDALTGLPNRAAFQRSGEAAVARAVsrrlgvRREGTTAVAVIDLDRFKAINDTLGPRNGDVLLRRIAERLASHTRKGDTV 97
cd01949        1 TDPLTGLPNRRAFEERLERLLARAR------RSGRPLALLLIDLDHFKQINDTYGHAAGDEVLKEVARRLRSSLRESDLV 74

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117928869  98 ARLGGDEFGLILRDT--ADPHDALCRIRGLIESELDVAGIPLAVEASIGYAVTPDDAATIEELLQYADVAVHHAKAR 172
cd01949       75 ARLGGDEFAILLPGTdlEEAEELAERLRKAIEEPFFIDGEEIRVTASIGIAEYPEDGEDLEELLRRADKALYQAKRS 151

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

128367

smart00052

EAL

Putative diguanylate phosphodiesterase

false

241

1e-64

242.12

99.17

2,195,2,76,271,80,161

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 196 EFRRAVTDNQLVLHYQPKAKLSDGAVEAIEALVRWHHPARGLLYPDVFVPLVEQTDLIDDLTRWVLRHALEDLATI--GD 273
smart00052     3 ELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWqaQG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 274 PHLAVAVNISARNLSRHTFAADVKAAVRRAGIEPHRLVLELTETALLFDPTRAHDVFTDLTSYGIRVSIDDFGRGQTSLG 353
smart00052    83 PPLRISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGYSSLS 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117928869 354 YLSALPLSEIKIDRTFVRDMVTNAAHAAIVRSVVELGHNLGLIVVAEGVETAEVGDELRECGCDVAQGYWFARPMPLVD 432
smart00052   163 YLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPLDD 241

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

32382

COG2200

Rtn

c-di-GMP phosphodiesterase class I (EAL domain) [Signal transduction mechanisms]

false

256

2e-60

227.90

98.05

2,190,1,83,273,85,167

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 191 LSLISEFRRAVTDNQLVLHYQPKAKLSDGAVEAIEALVRWHHPARGLLYPDVFVPLVEQTDLIDDLTRWVLRHALEDLAT 270
COG2200        2 LQLERDLRQALENGEFSLYYQPIVDLATGRIVGYEALLRWRHPDGGLISPGEFIPLAEETGLIVELGRWVLEEACRQLRT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 271 IGD-PHLAVAVNISARNLSRHTFAADVKAAVRRAGIEPHRLVLELTETALLFDPTRAHDVFTDLTSYGIRVSIDDFGRGQ 349
COG2200       82 WPRaGPLRLAVNLSPVQLRSPGLVDLLLRLLARLGLPPHRLVLEITESALIDDLDTALALLRQLRELGVRIALDDFGTGY 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 350 TSLGYLSALPLSEIKIDRTFVRDMVTNAAHAAIVRSVVELGHNLGLIVVAEGVETAEVGDELRECGCDVAQGYWFARPMP 429
COG2200      162 SSLSYLKRLPPDILKIDRSFVRDLETDARDQAIVRAIVALAHKLGLTVVAEGVETEEQLDLLRELGCDYLQGYLFSRPLP 241

                        250
                 ....*....|.
gi 117928869 430 LVDLRRWLAGS 440
COG2200      242 ADALDALLSSS 252

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

109613

pfam00563

EAL

EAL domain

false

236

6e-49

190.32

99.15

5,195,2,76,271,83,28,300,111,20,321,131,52,374,183,53

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 196 EFRRAVTDNQLVLHYQPKAKLSDGAVEAIEALVRWHHPARGLLYPDVFVPLVEQTDLIDDLTRWVLRHALEDLATI---- 271
pfam00563      3 ALREALENGEFSLYFQPIVDLRTGKVLGYEALLRWQHPDGGLIPPDEFLPLAERLGLIAELDRWVLEKALAQLAEWrgna 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 272 -GDPHLAVAVNISARNLSRHTFAADVKAAvRRAGIEPHRLVLELTETALLfDPTRAHDVFTDLTSYGIRVSIDDFGRGQT 350
pfam00563     83 lLPPDLPLSVNLSPASLLDPSFLEALLAL-KQGGLPPSRLVLEITESDLD-EDLRLLEALARLRSLGFRLALDDFGTGYS 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117928869 351 SLGYLSALPLSEIKIDRTFVRDMvTNAAHAAIVRSVVELGHNLGLIVVAEGVETAEVGDELRECGCDVAQGYWFARP 427
pfam00563    161 SLSYLSRLPPDYIKIDRSFIKDL-SDPESRALLRALIALARELGIKVVAEGVETEEQLELLKELGIDYVQGYLFSKP 236

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

128563

smart00267

GGDEF

diguanylate cyclase

false

163

4e-34

141.23

95.71

4,13,0,29,48,29,64,114,93,6,120,103,53

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  14 YQARHDALTGLPNRAAFQRSGEAAVARAVsrrlgvRREGTTAVAVIDLDRFKAINDTLGPRNGDVLLRRIAERLASHTRK 93
smart00267     1 RLAFRDPLTGLPNRRYFEEELEQELQRAQ------RQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRP 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  94 GDTVARLGGDEFGLILRDTadPHDALC----RIRGLIESELDVAGIPLAVEASIGYAVTPDDAATIEELLQYADVAVHHA 169
smart00267    75 GDLLARLGGDEFALLLPET--SLEEAIalaeRILQQLREPIIIHGIPLYLTISIGVAAYPNPGEDAEDLLKRADTALYQA 152


                 ....
gi 117928869 170 KARH 173
smart00267   153 KKAG 156

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

110022

pfam00990

GGDEF

GGDEF domain

false

160

1e-33

139.30

98.12

4,15,0,33,54,33,62,116,97,12,128,112,45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  16 ARHDALTGLPNRAAFQRSGEAAVARAVSRRLGVrregttAVAVIDLDRFKAINDTLGPRNGDVLLRRIAERLASHTRKGD 95
pfam00990      1 AAHDPLTGLPNRRYFEEELEQELQRAQRRQSPL------ALLLLDLDNFKRINDTYGHAVGDEVLQEVAQRLSSSLRRSD 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  96 TVARLGGDEFGLILRDTADPH--DALCRIRGLIES---ELDVAGIPLAVEASIGYAVTPDDAATIEELLQYADVAVHHAK 170
pfam00990     75 LVARLGGDEFAILLPDTSLEGaqELAERIRRLLAAlkiPHTLSGLPLYVTISIGIAAYPNDGEDAEDLLKRADQALYQAK 154


                 ...
gi 117928869 171 ARH 173
pfam00990    155 NQG 157

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

32381

COG2199

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction...

false

181

5e-30

127.54

97.79

4,0,4,42,48,46,72,120,120,35,155,156,25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869   1 MTRRLRTEVARNAYQARHDALTGLPNRAAFQRSGEAAVARAVsrrlgvRREGTTAVAVIDLDRFKAINDTLGPRNGDVLL 80
COG2199        5 LLTRLRKAEERLERLALHDPLTGLPNRRAFEERLERALARAR------RHGEPLALLLLDLDHFKQINDTYGHAAGDEVL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  81 RRIAERLASHTRKGDTVARLGGDEFGLILRDTADPHDALC--RIRGLIESELDVAGIPLAVEASIGYAVTPDDAATI-EE 157
COG2199       79 REVARRLRSNLREGDLVARLGGDEFAVLLPGTSLEEAARLaeRIRAALEEPFFLGGEELRVTVSIGVALYPEDGSDDaEL 158

                        170       180
                 ....*....|....*....|...
gi 117928869 158 LLQYADVAVHHAKARHLGVVRYH 180
COG2199      159 LLRRADLALYRAKRAGRNRVVVF 181

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

129356

TIGR00254

GGDEF

diguanylate cyclase (GGDEF) domain

false

165

4e-26

114.36

98.79

7,14,0,27,48,27,4,52,32,60,113,92,7,120,102,8,128,111,8,136,120,43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  15 QARHDALTGLPNRAAFQRSGEAAVARAvsrrlgvRREG-TTAVAVIDLDRFKAINDTLGPRNGDVLLRRIAERLASHTRK 93
TIGR00254      1 QAVRDPLTGLYNRRYLEEMLDSELKRA-------RRFQrSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  94 GDTVARLGGDEFGLILRDTaDPHDALC---RIRGLIES-ELDVAGIP-LAVEASIGYAVTPDDAATIEELLQYADVAVHH 168
TIGR00254     74 SDVVGRYGGEEFVVILPGT-PLEDALSkaeRLRDAINSkPIEVAGSEtLTVTVSIGVACYPGHGLTLEELLKRADEALYQ 152

                        170
                 ....*....|.
gi 117928869 169 AKARHLGVVRY 179
TIGR00254    153 AKKAGRNRVVV 163

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

34606

COG5001

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF...

false

true

false

663

3e-79

290.77

66.82

8,1,216,7,11,223,19,30,244,18,56,262,72,128,337,68,196,406,71,268,477,167,435,646,13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869   2 TRRLRTEvarNAYQARHDALTGLPNRAAF--QRSGEAAVARAVSRRLGVrregttavAVIDLDRFKAINDTLGPRNGDVL 79
COG5001      217 TRRLSDE---NDRLANLDSLTGLPNRRRFfaELDARLAAARQSGRRLVL--------GVIDLDGFKPVNDAFGHATGDRL 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  80 LRRIAERLASHTRKGDTVARLGGDEFGLILRDTADPHDALCRIRGLIES---ELDVAGIPLAVEASIGYAVTPDDAATIE 156
COG5001      286 LIEVGRRLKAFDGAPILAARLGGDEFALIIPALEDDALRVAGARALCESlqaPYDLRGVRVQVGASIGIAPFPSGADTSE 365

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 157 ELLQYADVAVHHAKARHLGVVRYHPSQNHYDAASLSLISE-FRRAVTDNQLVLHYQPKAKLSDGAVEAIEALVRWHHPAR 235
COG5001      366 QLFERADYALYHAKQNGKGAAVLFDARHEAAIRDMAVVEQaLRSADLEQELSVHFQPIVDIVSGKTIALEALARWHSPEI 445

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 236 GLLYPDVFVPLVEQTDLIDDLTRWVLRHALEDlATIGDPHLAVAVNISARNLSRHTFAADVKAAVRRAGIEPHRLVLELT 315
COG5001      446 GPVPPDVFIGIAERSGQIVELTRLLLAKALRE-ARAWPMDVRVSINLSARDLASMENVRRLLAIVSESCIAPHRLDFEIT 524

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 316 ETALLFDPTRAHDVFTDLTSYGIRVSIDDFGRGQTSLGYLSALPLSEIKIDRTFVRDMVTNAAHAAIVRSVVELGHNLGL 395
COG5001      525 ETAIVCDFDQARDALAALHELGVRTALDDFGTGYSSLSHLRALPLDKIKIDRSFVSDLEENPTSEDIVRTVLQLGRNLRM 604

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 117928869 396 IVVAEGVETAEVGDELRECGCDVAQGYWFARPMPLVDLRR--WLAGSDRGDFSLA 448
COG5001      605 ECVVEGVETEAQRDRVAALGATVMQGYHYARPMPAEERRRrgRGAGPDVWDADFC 659

-1

137662

PRK10060

RNase II stability modulator; Provisional

false

true

false

663

2e-70

261.59

64.71

9,10,226,5,15,236,25,48,261,67,115,334,8,123,347,4,136,351,42,178,394,39,218,433,56,274,491,164

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  11 RNAYQ-----ARHDALTGLPNRAAFQRSGEAAVARavsrrlgvRREGTTAVAVIDLDRFKAINDTLGPRNGDVLLRRIAE 85
PRK10060     227 RRAQErlrilANTDSITGLPNRNAIQELIDHAIAQ--------ADNNQVGIVYLDLDNFKKVNDAYGHMFGDQLLQDVSL 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  86 RLASHTRKGDTVARLGGDEFGLILRDTADP------HDALCRIR-----GLIEseldvagipLAVEASIGYAVTPDDAAT 154
PRK10060     299 AILSCLEEDQTLARLGGDEFLVLASHTSQAaleamaSRILTRLRlpfriGLIE---------VYTGCSIGIALSPEHGDD 369

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 155 IEELLQYADVAVHHAKARHLGVVR-YHPSQNHYDAASLSLISEFRRAVTDNQLVLHYQPKAKLSdGAVEAIEALVRWHHP 233
PRK10060     370 SESLIRSADTAMYTAKEGGRGQFCvFSPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWR-GEVRSLEALVRWQSP 448

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 234 ARGLLYPDVFVPLVEQTDLIDDLTRWVLRHALEDLATIGDP--HLAVAVNISARNLSRHTFAADVKAAVRRAGIEPHRLV 311
PRK10060     449 ERGLIPPLEFISYAEESGLIVPLGRWVILDVVRQAAKWRDKgiNLRVAVNVSARQLADQTIFTALKQVLQELNFEYCPID 528

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 312 LELTETALLFDPTRAHDVFTDLTSYGIRVSIDDFGRGQTSLGYLSALPLSEIKIDRTFVRDMVTNAAHAAIVRSVVELGH 391
PRK10060     529 VELTESCLIENEELALSVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQ 608

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 117928869 392 NLGLIVVAEGVETAEVGDELRECGCDVAQGYWFARPMPLVDLRRWLA 438
PRK10060     609 ALNLQVIAEGVETAKEDAFLTKNGVNERQGFLFAKPMPAVAFERWYK 655

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

3e-63

237.68

37.63

7,12,684,33,51,717,65,116,791,18,140,809,37,177,849,35,212,885,60,272,946,158

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869   13 AYQARHDALTGLPNRAAFQRSGEAAVARAVSRRlgvrreGTTAVAVIDLDRFKAINDTLGPRNGDVLLRRIAERLASHTR 92
PRK09776      685 SYSASHDALTGLANRASFEKQLREALQTVNSTH------QRHALVFIDLDRFKAVNDSAGHAAGDALLRELASLMLSMLR 758

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869   93 KGDTVARLGGDEFGLILRDTADPH---------DALCRIRGLIESELDVAGiplaveASIGYAVTPDDAATIEELLQYAD 163
PRK09776      759 SSDVLARLGGDEFGLLLPDCNVESarfiatriiSAINDYRFPWEGRVYRVG------ASAGITAIDDNNHQASEVMSQAD 832

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  164 VAVHHAKARHLGVV---RYHPSQNHYDAASLSLISEFRRAVTDNQLVLHYQP-KAKLSDGAVEAIEALVRWHHPARGLLY 239
PRK09776      833 IACYAAKNAGRGRVtvyEPQQAAAHSERRELSLAEQWRSMLEENQLMLQAQEiASPRIPEARNLWLISLRLWDCEGEIID 912

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  240 PDVFVPLVEQTDLIDDLTRWVLRHALEDLATIG-DPHLAVAVNISARNLSRHTFAADVKAAVRRAGIEPHRLVLELTETA 318
PRK09776      913 EGAFRPAAEDPALMHALDRWVIHELFQQGARAVaSKGLSIAIPLSVASLSSATLLPFLLEQLENSPLPPRLLHLEITETA 992

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  319 LLFDPTRAHDVFTDLTSYGIRVSIDDFGRGQTSLGYLSALPLSEIKIDRTFVRDMVTNAAHAAIVRSVVELGHNLGLIVV 398
PRK09776      993 LLNHAEAASRLVQKLRLAGCRVVLDDFGRGLSSFNYLKAFMADYLKIDGELCANLQGNLMDEMLVSIINGIAQRLGMKTI 1072

                         410       420       430
                  ....*....|....*....|....*....|..
gi 117928869  399 AEGVETAEVGDELRECGCDVAQGYWFARPMPL 430
PRK09776     1073 AGPVELPLTLDTLSGIGVDLAQGYVIGRPQPL 1104

-1

138538

PRK11359

cAMP phosphodiesterase; Provisional

false

true

false

799

2e-57

218.56

51.94

7,16,376,28,54,404,58,113,462,5,118,470,26,146,496,33,179,530,97,276,630,161

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  17 RHDALTGLPNRAAFQRSGEAAVARAVSRrlgvrregttAVAVIDLDRFKAINDTLGPRNGDVLLRRIAERLASHTRKGDT 96
PRK11359     377 QFDPMTGLPNRNNLHNYLDDLVDKAVSP----------VVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQY 446

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  97 VARLGGDEFGLILRDTaDPHDA---LCRIRGLIESELDVAGIPLAVEASIGyaVTPDDAATIEELLQYADVAVHHAKARH 173
PRK11359     447 LCRIEGTQFVLVSLEN-DVSNItqiADELRNVVSKPIMIDDKPFPLTLSIG--ISYDVGKNRDYLLSTAHNAMDYIRKNG 523

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 174 LGVVRY-HPSQNHYDAASLSLISEFRRAVTDNQLVLHYQPKAKLSDGAVEAIEALVRWHHPARGLLYPDVFVPLVEQTDL 252
PRK11359     524 GNGWQFfSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGE 603

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 253 IDDLTRWVLRHALEDLATIGDPHL---AVAVNISARNLSRHTFAADVKAAVRRAGIEPHRLVLELTETALLFDPTRAHDV 329
PRK11359     604 IENIGRWVIAEACRQLAEWRSQNIhipALSVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFKR 683

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 330 FTDLTSYGIRVSIDDFGRGQTSLGYLSALPLSEIKIDRTFVRDMVTNAAHAAIVRSVVELGHNLGLIVVAEGVETAEVGD 409
PRK11359     684 IQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFE 763

                        410       420
                 ....*....|....*....|....*...
gi 117928869 410 ELRECGCDVAQGYWFARPMPLVDLRRWL 437
PRK11359     764 MLRKIHCRVIQGYFFSRPLPAEEIPGWM 791

-1

34551

COG4943

Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]

Predicted signal transduction protein containing sensor and EAL domains [Signal...

false

true

false

524

1e-42

169.37

47.52

3,190,266,81,271,349,49,321,398,117

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 191 LSLISEFRRAVTDNQLVLHYQPKAKLSDGAVEAIEALVRWHHPARGLLYPDVFVPLVEQTDLIDDLTRWVLRHALEDLAT 270
COG4943      267 LSPRRRLQRAIERRELCVHYQPIVDLATGKCVGAEALARWPQEDGTVVSPDVFIPLAEESGMIEQITDYVIRNVFRDLGD 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 271 I--GDPHLAVAVNISARNLSRHTFAADVKAAVRRAGIEPHRLVLELTETALLfDPTRAHDVFTDLTSYGIRVSIDDFGRG 348
COG4943      347 LlrQHRDLHVSINLSASDLASPRLIDRLNRKLAQYQVRPQQIALELTERTFA-DPKKMTPIILRLREAGHEIYIDDFGTG 425

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 349 QTSLGYLSALPLSEIKIDRTFVRDMVTNAAHAAIVRSVVELGHNLGLIVVAEGVETAEVGDELRECGCDVAQGYWFARPM 428
COG4943      426 YSNLHYLQSLPVDALKIDKSFVDTLGTDSASHLIAPHIIEMAKSLGLKIVAEGVETEEQVDWLRKRGVHYGQGWLFSKAL 505

                        250
                 ....*....|
gi 117928869 429 PLVDLRRWLA 438
COG4943      506 PAQAFLDWAE 515

-1

139666

PRK13561

putative phosphodiesterase; Provisional

false

true

false

651

2e-41

164.94

64.36

10,14,229,27,51,256,69,120,328,32,153,360,13,168,373,7,175,383,99,274,484,82,356,569,20,379,589,54,433,644,4

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  15 QARHDALTGLPNRAAFQRSGEAAVARAvsrrlgvrreGTTAVAVIDLDRFKAINDTLGPRNGDVLLRRIAERLASHTRKG 94
PRK13561     230 NAMRFPVSDLPNKALLMALLEQVVARK----------QTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPR 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  95 DTVARLGGDEFGLILRDTADPHDALC---RIRGLIESELDVAGIPLAVEASIGYAVTPDDAaTIEELLQYADVAVhhAKA 171
PRK13561     300 MVLAQISGYDFAIIANGVKEPWHAITlgqQVLTIINERLPIQRIQLRPSCSIGIAMFYGDL-TAEQLYSRAVSAA--FTA 376

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 172 RHLG---VVRYHPSQNHYDAASLSLISEFRRAVTDNQLVLHYQPKAKLSDGAVEAIEALVRWHHPARGLLYPDVFVPLVE 248
PRK13561     377 RRKGknqIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMRSGKLVSAEALLRMQQPDGSWDLPDGLIDRIE 456

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 249 QTDLIDDLTRWVLRHALEDLATIGDP--HLAVAVNISARNLSRHTFAADVKAAVRRAGIEPHRLVLELTETALLFDPTRA 326
PRK13561     457 SCGLMVTVGHWVLEESCRLLAAWQERgiMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAA 536

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 327 HDVFTDLTSYGIRVSIDDFGRGQTSLGYLS---ALPLSEIKIDRTFVRDMVTNaahAAIVRSVVELGHNLGLIVVAEGVE 403
PRK13561     537 VAILRPLRNAGVRIALDDFGMGYAGLRQLQhmkSLPIDVLKIDKMFVDGLPED---SSMVAAIIMLAQSLNLQMIAEGVE 613

                        410       420       430
                 ....*....|....*....|....*....|....*
gi 117928869 404 TAEVGDELRECGCDVAQGYWFARPMPLVDL-RRWL 437
PRK13561     614 TEAQRDWLAKAGVGVAQGFLFARPLPIEIFeERYL 648

-1

137979

PRK10551

hypothetical protein; Provisional

false

true

false

518

1e-30

129.02

47.10

5,195,266,72,267,341,32,301,373,7,308,382,12,321,394,116

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 196 EFRRAVTDNQLVLHYQPKAKLSDGAVEAIEALVRWHHPARGLLYPDVFVPLVEQTDLIDDLTRWVLRHALED---LATIG 272
PRK10551     267 EILTAIKREQFYVVYQPVVDTQTLRVTGLEVLLRWRHPTAGEIPPDAFINYAEAQKLIVPLTQHLFELIARDaaeLQKVL 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 273 DPHLAVAVNISARNLSRHTFAADVKAAvrRAGIEPH--RLVLELTETALLfDPTRAHDVFTDLTSYGIRVSIDDFGRGQT 350
PRK10551     347 PVGAKLGINIAPAHLHSDSFKADVQRL--LASLPADhfQIVLEITERDML-QEEEALKLFAWLHSQGIEIAIDDFGTGHS 423

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 351 SLGYLSALPLSEIKIDRTFVRDMVTNAAHAAIVRSVVELGHNLGLIVVAEGVETAEVGDELRECGCDVAQGYWFARPMPL 430
PRK10551     424 ALIYLERFTLDYLKIDRGFINAIGTETVTSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLREHGVNFLQGYWISRPLPL 503


                 ....*..
gi 117928869 431 VDLRRWL 437
PRK10551     504 DDFVKWL 510

-1

138768

PRK11829

biofilm formation regulator HmsP; Provisional

false

true

false

728

2e-30

128.66

56.04

8,20,304,22,49,326,71,120,400,24,144,427,43,189,470,80,269,552,87,356,642,33,392,675,37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  21 LTGLPNRAAFQRSGEAAVARAVsrrlgvrREGTTAVAVIDLDRFKAINDTLGPRNGDVLLRRIAERLASHTRKGDTVARL 100
PRK11829     305 VTELPNRSLFISLLEKEIASST-------RTDHFHLLVIGIETLQEVSGAMSEAQHQQLLLTIVQRIEQCIDDSDLLAQL 377

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 101 GGDEFGLILRDTADPHDALC---RIRGLIESELDVAGIPLAVEASIG---YAVTPDDAATIEELLQYADVAVHHAKARHL 174
PRK11829     378 SKTEFAVLARGTRRSFPAMQlarRIMSQVTQPLFFDEITLRPSASIGitrYQAQQDTAESMMRNASTAMMAAHHEGRNQI 457

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 175 GVVRYHPSQNHYDaaSLSLISEFRRAVTDNQLVLHYQPKAKLSDGAVEAIEALVRWHHPARGLLYPDVFVPLVEQTDLID 254
PRK11829     458 MVFEPHLIEKTHK--RLTQENDLLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWCQPDGSYVLPSGFVHFAEEEGMMV 535

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 255 DLTRWVLRHALEDLA--TIGDPHLAVAVNISARNLSRHTFAADVKAAVRRAGIEPHRLVLELTETALLFDPTRAHDVFTD 332
PRK11829     536 PLGNWVLEEACRILAdwKARGVSLPLSVNISGLQVQNKQFLPHLKTLISHYHIDPQQLLLEITETAQIQDLDEALRLLRE 615

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 333 LTSYGIRVSIDDFGRGQTSLGYLS---ALPLSEIKIDRTFVRDMVTNAAHAAIVRSVVELghnLGLIVVAEGVETAEVGD 409
PRK11829     616 LQGLGLLIALDDFGIGYSSLRYLNhlkSLPIHMIKLDKSFVKNLPEDDAIARIISCVSDV---LKVRVMAEGVETEEQRQ 692

                        410       420
                 ....*....|....*....|
gi 117928869 410 ELRECGCDVAQGYWFARPMP 429
PRK11829     693 WLLEHGIQCGQGFLFSPPLP 712

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

5e-22

100.76

38.62

5,2,256,40,48,296,64,113,360,7,120,370,8,128,381,43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869   3 RRLRTEVARNAYQARHDALTGLPNRAAFQRSGEAAVARAVsrrlgvRREGTTAVAVIDLDRFKAINDTLGPRNGDVLLRR 82
COG3706      257 RQLRESLERLQELALVDGLTGLFNRRYFDEHLADLWKRAL------REGRPLSLLMLDIDDFKEINDTYGHDVGDEVLRQ 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  83 IAERLASHTRKGDTVARLGGDEFGLILRDTaDPHDALC---RIRGLIES---ELDVAGIPLAVEASIGYAVTPDDAATIE 156
COG3706      331 VARRLRQTVRGLDLVARYGGEEFAVVLPDT-DLEAAIAiaeRIRQKINElpfVHELSREPLEVTISIGVAEGKPGEDSIE 409

                        170
                 ....*....|....*
gi 117928869 157 ELLQYADVAVHHAKA 171
COG3706      410 ELLKRADKALYKAKA 424

-1

137400

PRK09581

pleD

response regulator PleD; Reviewed

false

true

false

457

3e-21

98.07

36.76

5,1,277,45,52,322,60,113,382,7,120,392,9,129,404,41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869   2 TRRLRTEVARNAYQARHDALTGLPNRAAFQRSGEAAVARAVSRRLgvrregTTAVAVIDLDRFKAINDTLGPRNGDVLLR 81
PRK09581     278 QDALRQNLEQSIEMAVTDGLTGLHNRRYFDMHLKQLIERANERGK------PLSLMMLDIDHFKQVNDTYGHDAGDEVLR 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  82 RIAERLASHTRKGDTVARLGGDEFGLILRDTaDPHDALC---RIRGLIESE---LDVAGIPLAVEASIGYAVTPDDAATI 155
PRK09581     352 EFAKRLRKNIRGTDLIARYGGEEFVVVMPDT-DIEVAIAvaeRIRRKIAEEpfaISDGKERLNVTVSIGVAELRPSGESI 430

                        170
                 ....*....|....*
gi 117928869 156 EELLQYADVAVHHAK 170
PRK09581     431 EALIKRADKALYEAK 445

-1

137576

PRK09894

hypothetical protein; Provisional

false

true

false

293

7e-20

93.62

49.83

5,18,132,28,54,160,60,114,222,12,126,235,22,149,257,21

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  19 DALTGLPNRAAFQRSGEAAVARAVSRRLgvrregttAVAVIDLDRFKAINDTLGPRNGDVLLRRIAERLASHTRKGDTVA 98
PRK09894     133 DVLTGLPGRRVLDESFDHQLRNREPLNL--------YLALLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRPYETVY 204

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 117928869  99 RLGGDEFGLILRDTAD--PHDALCRIRGLI-ESELDVAGIPLAVEASIGYAVTpDDAATIEELLQYADVAVHHAK 170
PRK09894     205 RYGGEEFIIILKAATDeeACRAGERIRQLIaNQAITHSEGRINITATFGVTRA-FPEEPLDEVIGRADRAMYEGK 278

-1

137615

PRK09966

hypothetical protein; Provisional

false

true

false

407

1e-14

76.60

40.54

6,3,235,27,31,262,14,51,276,66,118,342,15,133,362,18,152,380,20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869   4 RLRTEVARNAYQARHDALTGLPNRAAFqRSGEAAVARAVSRRlgvrreGTTAVAVIDLDRFKAINDTLGPRNGDVLLRRI 83
PRK09966     236 RLQAKNAQLLRTALHDPLTGLANRAAF-RSGINTLMNNSDAR------KTSALLFLDGDNFKYINDTWGHATGDRVLIEI 308

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  84 AERLASHTRKGDTVARLGGDEFGLILRDTADPHDaLCRIRGLIESELDVA-----GIPLAVEASIGYAVTPDDaATIEEL 158
PRK09966     309 AKRLAEFGGLRHKAYRLGGDEFAMVLYDVQSESE-VQQICSALTQIFNLPfdlhnGHQTTMTLSIGYAMTIEH-ASAEKL 386

                        170
                 ....*....|....
gi 117928869 159 LQYADVAVHHAKAR 172
PRK09966     387 QELADHNMYQAKHQ 400

-1

137770

PRK10245

adrA

diguanylate cyclase AdrA; Provisional

false

true

false

371

3e-09

58.37

42.32

6,2,203,9,18,212,9,31,221,22,55,243,57,114,300,24,138,328,32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869   3 RRLRTEVARnayqarhDALTGLPNRaafqRSGEAAVARAVSRRLGVRREGTtaVAVIDLDRFKAINDTLGPRNGDVLLRR 82
PRK10245     204 RRLQVMSTR-------DGMTGVYNR----RHWETMLRNEFDNCRRHNRDAT--LLIIDIDHFKSINDTWGHDVGDEAIVA 270

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  83 IAERLASHTRKGDTVARLGGDEFGLILRDTadPHDALCRIRGLIESELDVAGIPLA----VEASIGYAVTPDDAATIEEL 158
PRK10245     271 LTRQLQITLRGSDVIGRFGGDEFAVIMSGT--PAESAITAMLRVHEGLNTLRLPNApqvtLRISVGVAPLNPQMSHYREW 348

                        170
                 ....*....|..
gi 117928869 159 LQYADVAVHHAK 170
PRK10245     349 LKSADLALYKAK 360

-1

138376

PRK11059

regulatory protein CsrD; Provisional

false

true

false

642

3e-07

51.81

64.80

15,14,226,24,42,250,10,54,260,36,90,297,7,97,305,12,114,317,2,122,319,26,148,346,7,155,364,14,169,390,5,174,399,6,194,405,18,213,423,84,297,514,5,308,519,123

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  15 QARHDALTGLPNRAAFQRSGEAAVaravSRRLGVRREGttAVAVIDLDRFKAINDTLGPRNGDVLLRRIAERLASH-TRK 93
PRK11059     227 NAFLDAKTGLGNRLFFDNQLDTLL----EDQEKVGAHG--VVMLIRLPDFDLLQEELGESQVDELLFELINLLSTFvQRY 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869  94 GDTV-ARLGGDEFGLILrdtadPHdalcriRGLIESELDVAGIPLAVEASIGYAVT-PDDAATI-----------EELLQ 160
PRK11059     301 PGALlARYSRSDFAVLL-----PH------RSLKEADSLASQLLKAVDSLPPPKMLdRDDFLHIgiaayrsgqstEQVME 369

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 161 YADVAVHHA------------KARHL----GVVRYHpsqnhydaaslsliSEFRRAVTDNQLVLHYQPkAKLSDGAVEAI 224
PRK11059     370 EAEMALRSAqlqggnswfmydKAQDPekgrGSVRWR--------------TLLEQALVRGGPRLYQQP-VVTRDGQVHHR 434

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 225 EALVRWHHPARGLLYPDVFVPLVEQTDLIDDLTRWVLRHALEDLATIGDPHLAVAVNISARNLSRHTFAADVK------- 297
PRK11059     435 ELMCRIRDGQGNEVRAAEFMPMVLQCGLSEQYDRQVIERVLPLLSYWPEESQNLSINLSVDSLLSRAFQRWLRdtllqce 514

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928869 298 AAVRRagiephRLVLELTETALLFDPTRAHDVFTDLTSYGIRVSIDDFGRGQTSLGYLSALPLSEIKIDRTFVRDMVTNA 377
PRK11059     515 RSQRK------RLIFELAEADVVQHIDRLRPVLRMLRGLGCRLAVDQAGLTVVSTSYIKELNVELIKLHPSLVRNIHQRT 588

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....
gi 117928869 378 AHAAIVRSVVELGHNLGLIVVAEGVETAEVGDELRECGCDVAQGYWFARPMPLV 431
PRK11059     589 ENQLFVRSLVGACAGTETQVFAEGVESREEWQTLQILGVSGGQGDFFASPQPLD 642

-1

active site	0	10	10	true	133472	cd01949	GGDEF
I-site	1	3	3	true	133472	cd01949	GGDEF