NCBI Conserved Domain Search

NewSearch

CDD Home

Conserved domains on [gi\|117928641\|ref\|YP_873192.1\|]
diguanylate cyclase/phosphodiesterase with GAF sensor [Acidothermus cellulolyticus 11B]

Graphical summary show options »	Show site features Horizontal zoom: ×	?



List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH

of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

30163

cd01948

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

true

false

true

240

5e-69

257.83

100.00

3,485,0,79,566,79,104,670,184,56

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 486 TELRGALHRGEFVVHYQPIVELATGDILGAEALLRWNHPRRGLLTAAEFVPIAEDCGEMVEIGSWVLRTACAQARAWQRe 565
cd01948        1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQA- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 566 lGEAPFTISVNVSTAQLAGDTFAGYLKEVLENTGLAATSLVLDITEALVLREEPWLLARLEELKLLGVSLAVDDFGARYS 645
cd01948       80 -GGPDLRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYS 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 646 SLAGLPRLPLDMVKIDQAFIDAVGT-PEGSAFARKIVELAHTLDLQVIAEGVQTQQQFEELRRARCEFAQGYLFAEPVDT 724
cd01948      159 SLSYLKRLPVDYLKIDRSFVRDIETdPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPA 238


                 ..
gi 117928641 725 DR 726
cd01948      239 EE 240

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

133472

cd01949

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as domain of unknown function 1 (DUF1). It is widely present in bacteria and often links to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain has been suggested to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesiveness in bacteria.

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

true

false

true

157

5e-40

161.22

90.45

1,311,0,142

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 312 HDSLTGLASRALFLDRLNLGLAQAARSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLRASDTAARYGGD 391
cd01949        1 TDPLTGLPNRRAFEERLERLLARARRSGRPLALLLIDLDHFKQINDTYGHAAGDEVLKEVARRLRSSLRESDLVARLGGD 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 117928641 392 EFVALLHDTDVRGAAIVAARIIDAVRQPLRVGEMDVTVDASIGIACSVAGGTAADDLLRSAD 453
cd01949       81 EFAILLPGTDLEEAEELAERLRKAIEEPFFIDGEEIRVTASIGIAEYPEDGEDLEELLRRAD 142

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

128367

smart00052

EAL

Putative diguanylate phosphodiesterase

false

241

3e-67

251.75

98.34

3,484,0,83,569,83,96,665,180,57

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 485 ETELRGALHRGEFVVHYQPIVELATGDILGAEALLRWNHPRRGLLTAAEFVPIAEDCGEMVEIGSWVLRTACAQARAWQR 564
smart00052     1 ERELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 565 ELGeaPFTISVNVSTAQLAGDTFAGYLKEVLENTGLAATSLVLDITEALVLREEPWLLARLEELKLLGVSLAVDDFGARY 644
smart00052    81 QGP--PLRISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGY 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117928641 645 SSLAGLPRLPLDMVKIDQAFI-DAVGTPEGSAFARKIVELAHTLDLQVIAEGVQTQQQFEELRRARCEFAQGYLFAEPV 722
smart00052   159 SSLSYLKRLPVDLLKIDKSFVrDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPL 237

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

32382

COG2200

Rtn

c-di-GMP phosphodiesterase class I (EAL domain) [Signal transduction mechanisms]

false

256

5e-65

244.46

98.83

3,483,3,81,567,84,103,670,188,68

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 484 LETELRGALHRGEFVVHYQPIVELATGDILGAEALLRWNHPRRGLLTAAEFVPIAEDCGEMVEIGSWVLRTACAQARAWQ 563
COG2200        4 LERDLRQALENGEFSLYYQPIVDLATGRIVGYEALLRWRHPDGGLISPGEFIPLAEETGLIVELGRWVLEEACRQLRTWP 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 564 RelgEAPFTISVNVSTAQLAGDTFAGYLKEVLENTGLAATSLVLDITEALVLREEPWLLARLEELKLLGVSLAVDDFGAR 643
COG2200       84 R---AGPLRLAVNLSPVQLRSPGLVDLLLRLLARLGLPPHRLVLEITESALIDDLDTALALLRQLRELGVRIALDDFGTG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 644 YSSLAGLPRLPLDMVKIDQAFIDAVGT-PEGSAFARKIVELAHTLDLQVIAEGVQTQQQFEELRRARCEFAQGYLFAEPV 722
COG2200      161 YSSLSYLKRLPPDILKIDRSFVRDLETdARDQAIVRAIVALAHKLGLTVVAEGVETEEQLDLLRELGCDYLQGYLFSRPL 240

                        250
                 ....*....|....*.
gi 117928641 723 DTDRVPALRPTAQRLW 738
COG2200      241 PADALDALLSSSQSRV 256

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

109613

pfam00563

EAL

EAL domain

false

236

5e-57

217.67

100.00

4,484,0,78,562,79,31,594,110,19,614,129,107

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 485 ETELRGALHRGEFVVHYQPIVELATGDILGAEALLRWNHPRRGLLTAAEFVPIAEDCGEMVEIGSWVLRTACAQARAW-Q 563
pfam00563      1 EQALREALENGEFSLYFQPIVDLRTGKVLGYEALLRWQHPDGGLIPPDEFLPLAERLGLIAELDRWVLEKALAQLAEWrG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 564 RELGEAPFTISVNVSTAQLAGDTFAGYLKEvLENTGLAATSLVLDITEALvLREEPWLLARLEELKLLGVSLAVDDFGAR 643
pfam00563     81 NALLPPDLPLSVNLSPASLLDPSFLEALLA-LKQGGLPPSRLVLEITESD-LDEDLRLLEALARLRSLGFRLALDDFGTG 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117928641 644 YSSLAGLPRLPLDMVKIDQAFIDAVGTPEGSAFARKIVELAHTLDLQVIAEGVQTQQQFEELRRARCEFAQGYLFAEP 721
pfam00563    159 YSSLSYLSRLPPDYIKIDRSFIKDLSDPESRALLRALIALARELGIKVVAEGVETEEQLELLKELGIDYVQGYLFSKP 236

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

110022

pfam00990

GGDEF

GGDEF domain

false

160

5e-36

148.16

91.88

2,309,0,109,418,112,35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 310 AFHDSLTGLASRALFLDRLNLGLAQAARSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLRASDTAARYG 389
pfam00990      1 AAHDPLTGLPNRRYFEEELEQELQRAQRRQSPLALLLLDLDNFKRINDTYGHAVGDEVLQEVAQRLSSSLRRSDLVARLG 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117928641 390 GDEFVALLHDTDVRGAAIVAARIIDAVRQ---PLRVGEMDVTVDASIGIACSVAGGTAADDLLRSAD 453
pfam00990     81 GDEFAILLPDTSLEGAQELAERIRRLLAAlkiPHTLSGLPLYVTISIGIAAYPNDGEDAEDLLKRAD 147

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

128563

smart00267

GGDEF

diguanylate cyclase

false

163

7e-36

147.39

88.96

1,308,1,145

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 309 RAFHDSLTGLASRALFLDRLNLGLAQAARSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLRASDTAARY 388
smart00267     2 LAFRDPLTGLPNRRYFEEELEQELQRAQRQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRPGDLLARL 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 117928641 389 GGDEFVALLHDTDVRGAAIVAARIIDAVRQPLRVGEMDVTVDASIGIACSVAGGTAADDLLRSAD 453
smart00267    82 GGDEFALLLPETSLEEAIALAERILQQLREPIIIHGIPLYLTISIGVAAYPNPGEDAEDLLKRAD 146

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

32381

COG2199

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction...

false

181

9e-30

127.16

80.11

2,309,19,127,436,147,17

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 310 AFHDSLTGLASRALFLDRLNLGLAQAARSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLRASDTAARYG 389
COG2199       20 ALHDPLTGLPNRRAFEERLERALARARRHGEPLALLLLDLDHFKQINDTYGHAAGDEVLREVARRLRSNLREGDLVARLG 99

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 117928641 390 GDEFVALLHDTDVRGAAIVAARIIDAVRQPLRVGEMDVTVDASIGIA-CSVAGGTAADDLLRSAD 453
COG2199      100 GDEFAVLLPGTSLEEAARLAERIRAALEEPFFLGGEELRVTVSIGVAlYPEDGSDDAELLLRRAD 164

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

129356

TIGR00254

GGDEF

diguanylate cyclase (GGDEF) domain

false

165

5e-29

124.75

89.09

3,308,0,110,418,113,7,426,120,27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 309 RAFHDSLTGLASRALFLDRLNLGLAQAARSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLRASDTAARY 388
TIGR00254      1 QAVRDPLTGLYNRRYLEEMLDSELKRARRFQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117928641 389 GGDEFVALLHDTDVRGAAIVAARIIDAVRQ---PLRVGEMdVTVDASIGIACSVAGGTAADDLLRSAD 453
TIGR00254     81 GGEEFVVILPGTPLEDALSKAERLRDAINSkpiEVAGSET-LTVTVSIGVACYPGHGLTLEELLKRAD 147

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

138661

PRK11596

EAL domain-containing protein; Provisional

false

255

9e-05

44.31

39.22

2,634,154,26,660,181,73

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 635 LAVDDFGARYSSLAGLPRLPLDMVKI-DQAFIDAVGTPEGSAFARKIVELAHTLDLQVIAEGVQTQQQFEELRRARCEFA 713
PRK11596     155 LWLDDFGTGMANFSALSEVRYDYIKVaRELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQRSPAFAA 234

                         90       100
                 ....*....|....*....|
gi 117928641 714 QGYLFAEPVDTDRVPALRPT 733
PRK11596     235 QGYFLSRPAPFDTLETLPLA 254

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

128379

smart00065

GAF

Domain present in phytochromes and cGMP-specific phosphodiesterases.

true

false

149

3e-04

42.75

97.99

5,180,3,21,201,27,35,236,75,14,250,90,7,257,98,51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 181 DILDAVVRTVHEVLGVDTVII---RRGPSATVAARCGGTERTARWLARLPLPDGTTGGV-------------HDLETANP 244
smart00065     4 ELLQTILEELRQLLGADRVLIylvDEDDRGELVLVAADGLTLPLLGLRYPLGEGLAGRVaetgrplnipdveADPVFALD 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117928641 245 PAGIAV-TRALAGV-VHENGRIAGALIAATTDPARLWRDADREALGVFADHVTLAITDATTVEAMN 308
smart00065    84 LLGRYQgVRSFLAVpLVADGELVGVLALHNKDSPRPFTEEDEELLQALANQLAIALANAQLYEELR 149

cl00853

140972

GAF

GAF domain

-1

137662

PRK10060

RNase II stability modulator; Provisional

false

true

false

663

7e-79

290.48

61.09

6,312,239,22,336,261,171,508,432,57,565,490,2,570,492,100,670,593,51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 313 DSLTGLASRALFLDRLNLGLAQaaRSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLRASDTAARYGGDE 392
PRK10060     240 DSITGLPNRNAIQELIDHAIAQ--ADNNQVGIVYLDLDNFKKVNDAYGHMFGDQLLQDVSLAILSCLEEDQTLARLGGDE 317

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 393 FVALLHDTDVRGAAIVAARIIDAVRQPLRVGEMDVTVDASIGIACSVAGGTAADDLLRSADVAMYRAKRAGRGRYAIYEP 472
PRK10060     318 FLVLASHTSQAALEAMASRILTRLRLPFRIGLIEVYTGCSIGIALSPEHGDDSESLIRSADTAMYTAKEGGRGQFCVFSP 397

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 473 SMHAALLEQLHLETELRGALHRGEFVVHYQPIVELaTGDILGAEALLRWNHPRRGLLTAAEFVPIAEDCGEMVEIGSWVL 552
PRK10060     398 EMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITW-RGEVRSLEALVRWQSPERGLIPPLEFISYAEESGLIVPLGRWVI 476

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 553 RTACAQARAWQRE-LGeapFTISVNVSTAQLAGDTFAGYLKEVLENTGLAATSLVLDITEALVLREEPWLLARLEELKLL 631
PRK10060     477 LDVVRQAAKWRDKgIN---LRVAVNVSARQLADQTIFTALKQVLQELNFEYCPIDVELTESCLIENEELALSVIQQFSQL 553

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 632 GVSLAVDDFGARYSSLAGLPRLPLDMVKIDQAFIDAVGT-PEGSAFARKIVELAHTLDLQVIAEGVQTQQQFEELRRARC 710
PRK10060     554 GAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKqPVSQSLVRAIVAVAQALNLQVIAEGVETAKEDAFLTKNGV 633

                        410
                 ....*....|.
gi 117928641 711 EFAQGYLFAEP 721
PRK10060     634 NERQGFLFAKP 644

-1

34606

COG5001

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF...

false

true

false

663

6e-68

254.18

69.08

5,278,196,140,418,337,148,571,485,94,665,580,60,725,641,13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 279 WRDADREALGVFADHVTLAITDATTVEAMNRAFHDSLTGLASRALFLDRLNLGLAQAARSGTNLCLLFIDLDRFKIVNDT 358
COG5001      197 YREFSDMVQSQVTLTQRAEETRRLSDENDRLANLDSLTGLPNRRRFFAELDARLAAARQSGRRLVLGVIDLDGFKPVNDA 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 359 LGHAAGDVLLVEIANRLRSCLRASDTAARYGGDEFVALLHDTDVRGAAIVAARIIDAVRQ-PLRVGEMDVTVDASIGIAC 437
COG5001      277 FGHATGDRLLIEVGRRLKAFDGAPILAARLGGDEFALIIPALEDDALRVAGARALCESLQaPYDLRGVRVQVGASIGIAP 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 438 SVAGGTAADDLLRSADVAMYRAKRAGRGRYAIYEPSMHAALLEQLHLETELRGALHRGEFVVHYQPIVELATGDILGAEA 517
COG5001      357 FPSGADTSEQLFERADYALYHAKQNGKGAAVLFDARHEAAIRDMAVVEQALRSADLEQELSVHFQPIVDIVSGKTIALEA 436

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 518 LLRWNHPRRGLLTAAEFVPIAEDCGEMVEIGSWVLRTACAQARAWQRELgeapfTISVNVSTAQLAGDTFAGYLKEVLEN 597
COG5001      437 LARWHSPEIGPVPPDVFIGIAERSGQIVELTRLLLAKALREARAWPMDV-----RVSINLSARDLASMENVRRLLAIVSE 511

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 598 TGLAATSLVLDITEALVLREEPWLLARLEELKLLGVSLAVDDFGARYSSLAGLPRLPLDMVKIDQAFI-DAVGTPEGSAF 676
COG5001      512 SCIAPHRLDFEITETAIVCDFDQARDALAALHELGVRTALDDFGTGYSSLSHLRALPLDKIKIDRSFVsDLEENPTSEDI 591

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 117928641 677 ARKIVELAHTLDLQVIAEGVQTQQQFEELRRARCEFAQGYLFAEPVDTD-RVPALRPTAQRLW 738
COG5001      592 VRTVLQLGRNLRMECVVEGVETEAQRDRVAALGATVMQGYHYARPMPAEeRRRRGRGAGPDVW 654

-1

138538

PRK11359

cAMP phosphodiesterase; Provisional

false

true

false

799

3e-64

242.05

52.44

6,312,378,11,323,392,13,343,405,100,445,505,125,571,630,102,673,733,64

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 313 DSLTGLASRAL---FLDRLNLGLAQAArsgtnlcLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLRASDTAARYG 389
PRK11359     379 DPMTGLPNRNNlhnYLDDLVDKAVSPV-------VYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRIE 451

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 390 GDEFVALLHDTDVRGAAIVAARIIDAVRQPLRVGEMDVTVDASIGIACSVAGGTaaDDLLRSADVAMYRAKRAGRGRYAI 469
PRK11359     452 GTQFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISYDVGKNR--DYLLSTAHNAMDYIRKNGGNGWQF 529

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 470 YEPSMHAALLEQLHLETELRGALHRGEFVVHYQPIVELATGDILGAEALLRWNHPRRGLLTAAEFVPIAEDCGEMVEIGS 549
PRK11359     530 FSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGR 609

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 550 WVLRTACAQARAWQRELGEAPfTISVNVSTAQLAGDTFAGYLKEVLENTGLAATSLVLDITEALVLREEPWLLARLEELK 629
PRK11359     610 WVIAEACRQLAEWRSQNIHIP-ALSVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFKRIQILR 688

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 630 LLGVSLAVDDFGARYSSLAGLPRLPLDMVKIDQAFIDAVGTPEG-SAFARKIVELAHTLDLQVIAEGVQTQQQFEELRRA 708
PRK11359     689 DMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRiLALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKI 768

                        410       420
                 ....*....|....*....|....*....
gi 117928641 709 RCEFAQGYLFAEPVDTDRVPALRPTAQRL 737
PRK11359     769 HCRVIQGYFFSRPLPAEEIPGWMSSVLPL 797

-1

139666

PRK13561

putative phosphodiesterase; Provisional

false

true

false

651

4e-51

198.07

63.90

7,304,225,25,333,250,84,417,335,19,437,354,133,572,487,80,652,570,14,668,584,57

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 305 EAMNRAFHDSLTGLASRALFLDRLNlglaQAARSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLRASDT 384
PRK13561     226 EQNENAMRFPVSDLPNKALLMALLE----QVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMV 301

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 385 AARYGGDEFVALLHDTDVRGAAIVAARIIDAVR-QPLRVGEMDVTVDASIGIAcSVAGGTAADDLLRSADVAMYRAKRAG 463
PRK13561     302 LAQISGYDFAIIANGVKEPWHAITLGQQVLTIInERLPIQRIQLRPSCSIGIA-MFYGDLTAEQLYSRAVSAAFTARRKG 380

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 464 RGRYAIYEPSMHAALLEQLHLETELRGALHRGEFVVHYQPIVELATGDILGAEALLRWNHPRRGLLTAAEFVPIAEDCGE 543
PRK13561     381 KNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMRSGKLVSAEALLRMQQPDGSWDLPDGLIDRIESCGL 460

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 544 MVEIGSWVLRTACAQARAWQRELGEAPftISVNVSTAQLAGDTFAGYLKEVLENTGLAATSLVLDITEALVLREEPWLLA 623
PRK13561     461 MVTVGHWVLEESCRLLAAWQERGIMLP--LSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVA 538

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 624 RLEELKLLGVSLAVDDFGARYSSLAGLPR---LPLDMVKIDQAFIDavGTPEGSAFARKIVELAHTLDLQVIAEGVQTQQ 700
PRK13561     539 ILRPLRNAGVRIALDDFGMGYAGLRQLQHmksLPIDVLKIDKMFVD--GLPEDSSMVAAIIMLAQSLNLQMIAEGVETEA 616

                        410       420
                 ....*....|....*....|....*
gi 117928641 701 QFEELRRARCEFAQGYLFAEPVDTD 725
PRK13561     617 QRDWLAKAGVGVAQGFLFARPLPIE 641

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

9e-46

180.29

38.89

7,295,668,14,309,687,118,427,806,54,481,862,37,518,900,49,570,949,95,665,1045,57

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641  296 LAITDATTVEAMNR-----AFHDSLTGLASRALFLDRLNLGLAQAARSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVE 370
PRK09776      669 LVFQDVTESRAMLRqlsysASHDALTGLANRASFEKQLREALQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALLRE 748

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641  371 IANRLRSCLRASDTAARYGGDEFVALLHDTDVRGAAIVAARIIDAVRQPLRVGEMDV-TVDASIGIACSVAGGTAADDLL 449
PRK09776      749 LASLMLSMLRSSDVLARLGGDEFGLLLPDCNVESARFIATRIISAINDYRFPWEGRVyRVGASAGITAIDDNNHQASEVM 828

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641  450 RSADVAMYRAKRAGRGRYAIYEPSMHAALLEQ--LHLETELRGALHRGEFVVHYQPIVELATGDILGAEAL-LRWNHPRR 526
PRK09776      829 SQADIACYAAKNAGRGRVTVYEPQQAAAHSERreLSLAEQWRSMLEENQLMLQAQEIASPRIPEARNLWLIsLRLWDCEG 908

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641  527 GLLTAAEFVPIAEDCGEMVEIGSWVLRTACAQARAWQRELGeapFTISVNVSTAQLAGDTFAGYLKEVLENTGLAATSLV 606
PRK09776      909 EIIDEGAFRPAAEDPALMHALDRWVIHELFQQGARAVASKG---LSIAIPLSVASLSSATLLPFLLEQLENSPLPPRLLH 985

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641  607 LDITEALVLREEPWLLARLEELKLLGVSLAVDDFGARYSSLAGLPRLPLDMVKIDQAFI-DAVGTPEGSAFARKIVELAH 685
PRK09776      986 LEITETALLNHAEAASRLVQKLRLAGCRVVLDDFGRGLSSFNYLKAFMADYLKIDGELCaNLQGNLMDEMLVSIINGIAQ 1065

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 117928641  686 TLDLQVIAEGVQTQQQFEELRRARCEFAQGYLFAEPV 722
PRK09776     1066 RLGMKTIAGPVELPLTLDTLSGIGVDLAQGYVIGRPQ 1102

-1

138768

PRK11829

biofilm formation regulator HmsP; Provisional

false

true

false

728

1e-42

169.88

57.14

7,306,295,7,313,303,25,339,328,78,417,407,153,572,560,76,648,639,20,670,659,52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 307 MNRAFHD-SLTGLASRALFLDRLNLGLAQAARSgTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLRASDTA 385
PRK11829     296 MGRISHRfPVTELPNRSLFISLLEKEIASSTRT-DHFHLLVIGIETLQEVSGAMSEAQHQQLLLTIVQRIEQCIDDSDLL 374

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 386 ARYGGDEFVALLHDTDVRGAAIVAARIIDAVR-QPLRVGEMDVTVDASIGIACSVAGGTAADDLLRSADVAMYRAKRAGR 464
PRK11829     375 AQLSKTEFAVLARGTRRSFPAMQLARRIMSQVtQPLFFDEITLRPSASIGITRYQAQQDTAESMMRNASTAMMAAHHEGR 454

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 465 GRYAIYEPSMHAALLEQLHLETELRGALHRGEFVVHYQPIVELATGDILGAEALLRWNHPRRGLLTAAEFVPIAEDCGEM 544
PRK11829     455 NQIMVFEPHLIEKTHKRLTQENDLLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWCQPDGSYVLPSGFVHFAEEEGMM 534

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 545 VEIGSWVLRTACAQARAWQRELGEAPftISVNVSTAQLAGDTFAGYLKEVLENTGLAATSLVLDITEALVLREEPWLLAR 624
PRK11829     535 VPLGNWVLEEACRILADWKARGVSLP--LSVNISGLQVQNKQFLPHLKTLISHYHIDPQQLLLEITETAQIQDLDEALRL 612

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 625 LEELKLLGVSLAVDDFGARYSSLA---GLPRLPLDMVKIDQAFIDAVgtPEGSAFARKIVELAHTLDLQVIAEGVQTQQQ 701
PRK11829     613 LRELQGLGLLIALDDFGIGYSSLRylnHLKSLPIHMIKLDKSFVKNL--PEDDAIARIISCVSDVLKVRVMAEGVETEEQ 690

                        410       420
                 ....*....|....*....|.
gi 117928641 702 FEELRRARCEFAQGYLFAEPV 722
PRK11829     691 RQWLLEHGIQCGQGFLFSPPL 711

-1

34551

COG4943

Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]

Predicted signal transduction protein containing sensor and EAL domains [Signal...

false

true

false

524

7e-42

167.44

45.23

4,483,268,82,567,350,48,616,398,58,674,457,48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 484 LETELRGALHRGEFVVHYQPIVELATGDILGAEALLRWNHPRRGLLTAAEFVPIAEDCGEMVEIGSWVLRTACAQARAWQ 563
COG4943      269 PRRRLQRAIERRELCVHYQPIVDLATGKCVGAEALARWPQEDGTVVSPDVFIPLAEESGMIEQITDYVIRNVFRDLGDLL 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 564 RElgEAPFTISVNVSTAQLAGDTFAGYLKEVLENTGLAATSLVLDITEALVLrEEPWLLARLEELKLLGVSLAVDDFGAR 643
COG4943      349 RQ--HRDLHVSINLSASDLASPRLIDRLNRKLAQYQVRPQQIALELTERTFA-DPKKMTPIILRLREAGHEIYIDDFGTG 425

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 644 YSSLAGLPRLPLDMVKIDQAFIDAVGTPEGS-AFARKIVELAHTLDLQVIAEGVQTQQQFEELRRARCEFAQGYLFAEPV 722
COG4943      426 YSNLHYLQSLPVDALKIDKSFVDTLGTDSAShLIAPHIIEMAKSLGLKIVAEGVETEEQVDWLRKRGVHYGQGWLFSKAL 505

-1

137979

PRK10551

hypothetical protein; Provisional

false

true

false

518

2e-29

125.94

45.56

4,484,264,82,567,346,52,620,398,52,672,451,49

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 485 ETELRGALHRGEFVVHYQPIVELATGDILGAEALLRWNHPRRGLLTAAEFVPIAEDCGEMVEIGSWVLRTACAQARAWQR 564
PRK10551     265 GREILTAIKREQFYVVYQPVVDTQTLRVTGLEVLLRWRHPTAGEIPPDAFINYAEAQKLIVPLTQHLFELIARDAAELQK 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 565 ELgEAPFTISVNVSTAQLAGDTFAGYLKEVLENTGLAATSLVLDITEALVLREEPwLLARLEELKLLGVSLAVDDFGARY 644
PRK10551     345 VL-PVGAKLGINIAPAHLHSDSFKADVQRLLASLPADHFQIVLEITERDMLQEEE-ALKLFAWLHSQGIEIAIDDFGTGH 422

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117928641 645 SSLAGLPRLPLDMVKIDQAFIDAVGTPE-GSAFARKIVELAHTLDLQVIAEGVQTQQQFEELRRARCEFAQGYLFAEP 721
PRK10551     423 SALIYLERFTLDYLKIDRGFINAIGTETvTSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLREHGVNFLQGYWISRP 500

-1

137400

PRK09581

pleD

response regulator PleD; Reviewed

false

true

false

457

2e-24

109.24

32.82

3,306,288,112,418,401,4,422,407,31

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 307 MNRAFHDSLTGLASRALFLDRLNLGLAQAARSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLRASDTAA 386
PRK09581     289 IEMAVTDGLTGLHNRRYFDMHLKQLIERANERGKPLSLMMLDIDHFKQVNDTYGHDAGDEVLREFAKRLRKNIRGTDLIA 368

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 387 RYGGDEFVALLHDTDVRGAAIVAARIIDAVRQ-PLRV--GEMDVTVDASIGIACSVAGGTAADDLLRSAD 453
PRK09581     369 RYGGEEFVVVMPDTDIEVAIAVAERIRRKIAEePFAIsdGKERLNVTVSIGVAELRPSGESIEALIKRAD 438

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

4e-24

108.47

35.86

2,300,260,118,418,381,35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 301 ATTVEAMNRAFHDSLTGLASRALFLDRLNLGLAQAARSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLR 380
COG3706      261 ESLERLQELALVDGLTGLFNRRYFDEHLADLWKRALREGRPLSLLMLDIDDFKEINDTYGHDVGDEVLRQVARRLRQTVR 340

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117928641 381 ASDTAARYGGDEFVALLHDTDVRGAAIVAARIIDAVRQ---PLRVGEMDVTVDASIGIACSVAGGTAADDLLRSAD 453
COG3706      341 GLDLVARYGGEEFAVVLPDTDLEAAIAIAERIRQKINElpfVHELSREPLEVTISIGVAEGKPGEDSIEELLKRAD 416

-1

138376

PRK11059

regulatory protein CsrD; Provisional

false

true

false

642

3e-19

92.64

64.17

14,309,227,70,379,298,6,385,305,12,397,318,23,420,342,9,431,351,13,445,364,32,477,406,4,490,410,16,507,426,56,567,482,25,592,508,67,659,583,3,669,586,53

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 310 AFHDSLTGLASRALFLDRLNLGLAQAARSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCL-RASDTA-AR 387
PRK11059     228 AFLDAKTGLGNRLFFDNQLDTLLEDQEKVGAHGVVMLIRLPDFDLLQEELGESQVDELLFELINLLSTFVqRYPGALlAR 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 388 YGGDEFVALL-HDTDVRGAAIVAARIIDAVRQPL-RVGEMDVTVdaSIGIACSVAGGTAaDDLLRSADVAMYRAKRAGRG 465
PRK11059     308 YSRSDFAVLLpHRSLKEADSLASQLLKAVDSLPPpKMLDRDDFL--HIGIAAYRSGQST-EQVMEEAEMALRSAQLQGGN 384

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 466 RYAIYEPSMHAA----------LLEQlhletelrgALHRGEFVVHYQPIVElATGDILGAEALLRWNHPRRGLLTAAEFV 535
PRK11059     385 SWFMYDKAQDPEkgrgsvrwrtLLEQ---------ALVRGGPRLYQQPVVT-RDGQVHHRELMCRIRDGQGNEVRAAEFM 454

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 536 PIAEDCGEMVEIGSWVLRTACAQARAWQrelgEAPFTISVNVSTAQLAGDTFAGYLK-EVLENTGLAATSLVLDITEALV 614
PRK11059     455 PMVLQCGLSEQYDRQVIERVLPLLSYWP----EESQNLSINLSVDSLLSRAFQRWLRdTLLQCERSQRKRLIFELAEADV 530

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 615 LREEPWLLARLEELKLLGVSLAVDDFGARYSSLAGLPRLPLDMVK--------IDQafidavgTPEGSAFARKIVELAHT 686
PRK11059     531 VQHIDRLRPVLRMLRGLGCRLAVDQAGLTVVSTSYIKELNVELIKlhpslvrnIHQ-------RTENQLFVRSLVGACAG 603

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 117928641 687 LDLQVIAEGVQTQQQFEELRRARCEFAQGYLFAEPV 722
PRK11059     604 TETQVFAEGVESREEWQTLQILGVSGGQGDFFASPQ 639

-1

137576

PRK09894

hypothetical protein; Provisional

false

true

false

293

6e-19

91.31

59.73

4,277,97,57,336,154,63,399,218,44,444,262,10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 278 LWRDADREALGVFADHVTLAITDATTVEAMNRAFHDSLTGLASRALFLDRLNLGLAQaaRSGTNLCLLFIDLDRFKIVND 357
PRK09894      98 HWQDADFDAFQEGLLSFTAALTDYKIYLLTIRSNMDVLTGLPGRRVLDESFDHQLRN--REPLNLYLALLDIDRFKLVND 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 358 TLGHAAGDVLLVEIANRLRSCLRASDTAARYGGDEFVALLHD-TDVRGAAIVAARIIDAVRQPLRVGEMDVTVDASIGIA 436
PRK09894     176 TYGHLIGDVVLRTLATYLASWTRPYETVYRYGGEEFIIILKAaTDEEACRAGERIRQLIANQAITHSEGRINITATFGVT 255

                        170
                 ....*....|....*...
gi 117928641 437 CSVAGGTaADDLLRSADV 454
PRK09894     256 RAFPEEP-LDEVIGRADR 272

-1

137615

PRK09966

hypothetical protein; Provisional

false

true

false

407

2e-15

79.29

24.08

3,300,238,29,329,268,11,342,279,57

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 301 ATTVEAMNRAFHDSLTGLASRALFLDRLN-LGLAQAARSGTnlCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCL 379
PRK09966     239 AKNAQLLRTALHDPLTGLANRAAFRSGINtLMNNSDARKTS--ALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEFG 316

                         90       100
                 ....*....|....*....|
gi 117928641 380 RASDTAARYGGDEFVALLHD 399
PRK09966     317 GLRHKAYRLGGDEFAMVLYD 336

-1

137770

PRK10245

adrA

diguanylate cyclase AdrA; Provisional

false

true

false

371

1e-09

60.68

23.72

1,312,212,88

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 313 DSLTGLASRALFLDRLNLGLAQAARSGTNLCLLFIDLDRFKIVNDTLGHAAGDVLLVEIANRLRSCLRASDTAARYGGDE 392
PRK10245     213 DGMTGVYNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDE 292


                 ....*...
gi 117928641 393 FVALLHDT 400
PRK10245     293 FAVIMSGT 300

-1

33240

COG3434

Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]

Predicted signal transduction protein containing EAL and modified HD-GYP domains [...

false

true

false

407

8e-07

51.05

25.06

6,631,110,9,641,119,14,655,134,6,664,140,7,675,147,46,721,196,16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928641 632 GVSLAVDDFgARYSSLAGLPRLPL-DMVKIDqafIDAVGTPegsaFARKIVELAHTLDLQVIAEGVQTQQQFEELRRARC 710
COG3434      111 GYLLALDDF-IFSNVSEWKPLLPLsDIVKID---FKRVTFD----KARLFDRDLGYINKKFLAEKVETEEEFEQAKKAGF 182

                         90       100       110
                 ....*....|....*....|....*....|
gi 117928641 711 EFAQGYLFAEP---VDTDRVPALRPTAQRL 737
COG3434      183 DLFQGYFFSKPeiiKRGRLSPFLKTTIELL 212

-1

active site	0	10	10	true	133472	cd01949	GGDEF
I-site	1	3	3	true	133472	cd01949	GGDEF