NCBI Conserved Domain Search

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Conserved domains on [gi\|117928031\|ref\|YP_872582.1\|]
diguanylate cyclase/phosphodiesterase [Acidothermus cellulolyticus 11B]

Graphical summary show options »	Show site features Horizontal zoom: ×	?



List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

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of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

30163

cd01948

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

true

false

true

240

2e-64

242.43

98.75

1,287,0,237

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 288 AELDAALRTGQLVLHYQSTVDLATGRTVGVEALLRWQHPRRGLLRPAEFLPAAEQSELIGLVTSYVLDAALASAVHWRQK 367
cd01948        1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLARWQAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 368 GIALPVSVNISARDLHDPSFPDRVDTLLHLHGVPADRLTLEITETTLNSRLYPADAVAKKLRDLGVRLSCDDFGTGTTPL 447
cd01948       81 GPDLRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYSSL 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117928031 448 PRLRDLPLAELKIDNTLIAGIVGDDDKRAIVAAVVELGRVFDLTVVAEGIERQDEREVLIRLGCTTGQGYYFSPPVP 524
cd01948      161 SYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLP 237

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

133472

cd01949

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as domain of unknown function 1 (DUF1). It is widely present in bacteria and often links to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain has been suggested to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesiveness in bacteria.

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

true

false

true

157

3e-31

131.94

96.82

2,112,0,90,203,90,62

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 113 RDDLTGVANRPALLAALDDTFEDIHRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVRHRDVVARLGAD 192
cd01949        1 TDPLTGLPNRRAFEERLERLLARARRSGRPLALLLIDLDHFKQINDTYGHAAGDEVLKEVARRLRSSLRESDLVARLGGD 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 117928031 193 EFAVLLRDFNrPEGADAMSRAILRALREPFDVAGLPLTLDVAAGLAVAPRDADTSAELLRRAMVALQAARHAR 265
cd01949       81 EFAILLPGTD-LEEAEELAERLRKAIEEPFFIDGEEIRVTASIGIAEYPEDGEDLEELLRRADKALYQAKRSG 152

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

128367

smart00052

EAL

Putative diguanylate phosphodiesterase

false

241

5e-64

240.58

97.93

1,288,2,236

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 289 ELDAALRTGQLVLHYQSTVDLATGRTVGVEALLRWQHPRRGLLRPAEFLPAAEQSELIGLVTSYVLDAALASAVHWRQKG 368
smart00052     3 ELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQAQG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 369 IALPVSVNISARDLHDPSFPDRVDTLLHLHGVPADRLTLEITETTLNSRLYPADAVAKKLRDLGVRLSCDDFGTGTTPLP 448
smart00052    83 PPLRISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGYSSLS 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117928031 449 RLRDLPLAELKIDNTLIAGIVGDDDKRAIVAAVVELGRVFDLTVVAEGIERQDEREVLIRLGCTTGQGYYFSPPVP 524
smart00052   163 YLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLP 238

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

32382

COG2200

Rtn

c-di-GMP phosphodiesterase class I (EAL domain) [Signal transduction mechanisms]

false

256

9e-59

223.28

100.00

2,282,0,86,369,86,170

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 283 RLTLHAELDAALRTGQLVLHYQSTVDLATGRTVGVEALLRWQHPRRGLLRPAEFLPAAEQSELIGLVTSYVLDAALASAV 362
COG2200        1 RLQLERDLRQALENGEFSLYYQPIVDLATGRIVGYEALLRWRHPDGGLISPGEFIPLAEETGLIVELGRWVLEEACRQLR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 363 HWRQKGiALPVSVNISARDLHDPSFPDRVDTLLHLHGVPADRLTLEITETTLNSRLYPADAVAKKLRDLGVRLSCDDFGT 442
COG2200       81 TWPRAG-PLRLAVNLSPVQLRSPGLVDLLLRLLARLGLPPHRLVLEITESALIDDLDTALALLRQLRELGVRIALDDFGT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 443 GTTPLPRLRDLPLAELKIDNTLIAGIVGDDDKRAIVAAVVELGRVFDLTVVAEGIERQDEREVLIRLGCTTGQGYYFSPP 522
COG2200      160 GYSSLSYLKRLPPDILKIDRSFVRDLETDARDQAIVRAIVALAHKLGLTVVAEGVETEEQLDLLRELGCDYLQGYLFSRP 239

                        250
                 ....*....|....*..
gi 117928031 523 VPGALIGDVLRPDGERA 539
COG2200      240 LPADALDALLSSSQSRV 256

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

109613

pfam00563

EAL

EAL domain

false

236

3e-53

204.96

100.00

5,286,0,83,369,86,27,397,113,27,425,140,43,469,183,53

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 287 HAELDAALRTGQLVLHYQSTVDLATGRTVGVEALLRWQHPRRGLLRPAEFLPAAEQSELIGLVTSYVLDAALASAVHWRQ 366
pfam00563      1 EQALREALENGEFSLYFQPIVDLRTGKVLGYEALLRWQHPDGGLIPPDEFLPLAERLGLIAELDRWVLEKALAQLAEWRG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 367 KGI---ALPVSVNISARDLHDPSFPDRVDTLLHlHGVPADRLTLEITETTLNSRLYPADAVaKKLRDLGVRLSCDDFGTG 443
pfam00563     81 NALlppDLPLSVNLSPASLLDPSFLEALLALKQ-GGLPPSRLVLEITESDLDEDLRLLEAL-ARLRSLGFRLALDDFGTG 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117928031 444 TTPLPRLRDLPLAELKIDNTLIAGIvGDDDKRAIVAAVVELGRVFDLTVVAEGIERQDEREVLIRLGCTTGQGYYFSPP 522
pfam00563    159 YSSLSYLSRLPPDYIKIDRSFIKDL-SDPESRALLRALIALARELGIKVVAEGVETEEQLELLKELGIDYVQGYLFSKP 236

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

110022

pfam00990

GGDEF

GGDEF domain

false

160

5e-28

120.81

97.50

2,110,0,103,213,105,51

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 111 AGRDDLTGVANRPALLAALDDTFEDIHRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVRHRDVVARLG 190
pfam00990      1 AAHDPLTGLPNRRYFEEELEQELQRAQRRQSPLALLLLDLDNFKRINDTYGHAVGDEVLQEVAQRLSSSLRRSDLVARLG 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117928031 191 ADEFAVLLRDFNRPEGADAMSRA--ILRALREPFDVAGLPLTLDVAAGLAVAPRDADTSAELLRRAMVALQAARHA 264
pfam00990     81 GDEFAILLPDTSLEGAQELAERIrrLLAALKIPHTLSGLPLYVTISIGIAAYPNDGEDAEDLLKRADQALYQAKNQ 156

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

128563

smart00267

GGDEF

diguanylate cyclase

false

163

1e-26

116.58

95.09

2,108,0,94,203,94,61

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 109 EHAGRDDLTGVANRPALLAALDDTFEDIHRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVRHRDVVAR 188
smart00267     1 RLAFRDPLTGLPNRRYFEEELEQELQRAQRQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRPGDLLAR 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117928031 189 LGADEFAVLLRDFNrPEGADAMSRAILRALREPFDVAGLPLTLDVAAGLAVAPRDADTSAELLRRAMVALQAARHA 264
smart00267    81 LGGDEFALLLPETS-LEEAIALAERILQQLREPIIIHGIPLYLTISIGVAAYPNPGEDAEDLLKRADTALYQAKKA 155

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

32381

COG2199

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction...

false

181

3e-25

111.75

90.06

3,101,10,99,201,109,48,249,158,15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 102 ATHRRASEHAGRDDLTGVANRPALLAALDDTFEDIHRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVR 181
COG2199       11 KAEERLERLALHDPLTGLPNRRAFEERLERALARARRHGEPLALLLLDLDHFKQINDTYGHAAGDEVLREVARRLRSNLR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 182 HRDVVARLGADEFAVLLRDfNRPEGADAMSRAILRALREPFDVAGLPLTLDVAAGLAVAPRDADTSAE-LLRRAMVALQA 260
COG2199       91 EGDLVARLGGDEFAVLLPG-TSLEEAARLAERIRAALEEPFFLGGEELRVTVSIGVALYPEDGSDDAElLLRRADLALYR 169


                 ....
gi 117928031 261 ARHA 264
COG2199      170 AKRA 173

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

129356

TIGR00254

GGDEF

diguanylate cyclase (GGDEF) domain

false

165

1e-19

93.55

93.94

2,110,1,118,228,120,36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 111 AGRDDLTGVANRPALLAALDDTFEDIHRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVRHRDVVARLG 190
TIGR00254      2 AVRDPLTGLYNRRYLEEMLDSELKRARRFQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRYG 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 117928031 191 ADEFAVLLRDFNRPEGADAMSRAILRALREPFDVAGLP-LTLDVAAGLAVAPRDADTSAELLRRAMVALQAARHA 264
TIGR00254     82 GEEFVVILPGTPLEDALSKAERLRDAINSKPIEVAGSEtLTVTVSIGVACYPGHGLTLEELLKRADEALYQAKKA 156

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

138661

PRK11596

EAL domain-containing protein; Provisional

false

255

0.003

38.92

35.69

1,433,153,91

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 434 RLSCDDFGTGTTPLPRLRDLPLAELKIDNTLIAGIVGDDDKRAIVAAVVELGRVFDLTVVAEGIERQDEREVLIRLGCTT 513
PRK11596     154 PLWLDDFGTGMANFSALSEVRYDYIKVARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQRSPAFA 233

                         90
                 ....*....|.
gi 117928031 514 GQGYYFSPPVP 524
PRK11596     234 AQGYFLSRPAP 244

cl00290

140582

EAL

EAL domain. This domain is found in diverse bacterial signaling proteins. It is called...

-1

34606

COG5001

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF...

false

true

false

663

6e-67

250.33

61.99

2,110,227,256,369,483,155

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 111 AGRDDLTGVANRPALLAALDDTFEDIHRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVRHRDVVARLG 190
COG5001      228 ANLDSLTGLPNRRRFFAELDARLAAARQSGRRLVLGVIDLDGFKPVNDAFGHATGDRLLIEVGRRLKAFDGAPILAARLG 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 191 ADEFAVLLRDFNRPEGADAMSRAILRALREPFDVAGLPLTLDVAAGLAVAPRDADTSAELLRRAMVALQAARHARSPAVE 270
COG5001      308 GDEFALIIPALEDDALRVAGARALCESLQAPYDLRGVRVQVGASIGIAPFPSGADTSEQLFERADYALYHAKQNGKGAAV 387

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 271 NYRPAHDPAGAERLTLHAELDAALRTGQLVLHYQSTVDLATGRTVGVEALLRWQHPRRGLLRPAEFLPAAEQSELIGLVT 350
COG5001      388 LFDARHEAAIRDMAVVEQALRSADLEQELSVHFQPIVDIVSGKTIALEALARWHSPEIGPVPPDVFIGIAERSGQIVELT 467

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 351 SYVLDAALASAVHWRQkgiALPVSVNISARDLHDPSFPDRVDTLLHLHGVPADRLTLEITETTLNSRLYPADAVAKKLRD 430
COG5001      468 RLLLAKALREARAWPM---DVRVSINLSARDLASMENVRRLLAIVSESCIAPHRLDFEITETAIVCDFDQARDALAALHE 544

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 431 LGVRLSCDDFGTGTTPLPRLRDLPLAELKIDNTLIAGIVGDDDKRAIVAAVVELGRVFDLTVVAEGIERQDEREVLIRLG 510
COG5001      545 LGVRTALDDFGTGYSSLSHLRALPLDKIKIDRSFVSDLEENPTSEDIVRTVLQLGRNLRMECVVEGVETEAQRDRVAALG 624

                        410
                 ....*....|....
gi 117928031 511 CTTGQGYYFSPPVP 524
COG5001      625 ATVMQGYHYARPMP 638

-1

137662

PRK10060

RNase II stability modulator; Provisional

false

true

false

663

3e-62

234.62

64.71

6,98,219,5,103,225,7,110,236,25,137,261,68,206,329,103,310,432,216

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031  99 GTTAT-HRRASEH----AGRDDLTGVANRPALLAALDDTFEDihRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIA 173
PRK10060     220 GTDITeERRAQERlrilANTDSITGLPNRNAIQELIDHAIAQ--ADNNQVGIVYLDLDNFKKVNDAYGHMFGDQLLQDVS 297

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 174 MRLASRVRHRDVVARLGADEFAVLLRDFNRPEgADAMSRAILRALREPFDVAGLPLTLDVAAGLAVAPRDADTSAELLRR 253
PRK10060     298 LAILSCLEEDQTLARLGGDEFLVLASHTSQAA-LEAMASRILTRLRLPFRIGLIEVYTGCSIGIALSPEHGDDSESLIRS 376

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 254 AMVALQAARHARSPAVENYRPAHDPAGAERLTLHAELDAALRTGQLVLHYQSTVDLaTGRTVGVEALLRWQHPRRGLLRP 333
PRK10060     377 ADTAMYTAKEGGRGQFCVFSPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITW-RGEVRSLEALVRWQSPERGLIPP 455

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 334 AEFLPAAEQSELIGLVTSYVLDAALASAVHWRQKGIALPVSVNISARDLHDPSFPDRVDTLLHLHGVPADRLTLEITETT 413
PRK10060     456 LEFISYAEESGLIVPLGRWVILDVVRQAAKWRDKGINLRVAVNVSARQLADQTIFTALKQVLQELNFEYCPIDVELTESC 535

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 414 LNSRLYPADAVAKKLRDLGVRLSCDDFGTGTTPLPRLRDLPLAELKIDNTLIAGIVGDDDKRAIVAAVVELGRVFDLTVV 493
PRK10060     536 LIENEELALSVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQVI 615

                        410       420       430
                 ....*....|....*....|....*....|...
gi 117928031 494 AEGIERQDEREVLIRLGCTTGQGYYFSPPVPGA 526
PRK10060     616 AEGVETAKEDAFLTKNGVNERQGFLFAKPMPAV 648

-1

138538

PRK11359

cAMP phosphodiesterase; Provisional

false

true

false

799

5e-57

217.40

51.94

6,113,378,29,146,407,54,201,461,38,239,500,7,249,507,123,372,631,162

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 114 DDLTGVANRPALLAALDDTFEDIHRRAAYagllVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVRHRDVVARLGADE 193
PRK11359     379 DPMTGLPNRNNLHNYLDDLVDKAVSPVVY----LIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRIEGTQ 454

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 194 FAVLLRDfNRPEGADAMSRAILRALREPFDVAGLPLTLDVAAGLAV-APRDADTsaeLLRRAMVALQAARHARSPAVENY 272
PRK11359     455 FVLVSLE-NDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISYdVGKNRDY---LLSTAHNAMDYIRKNGGNGWQFF 530

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 273 RPAHDPAGAERLTLHAELDAALRTGQLVLHYQSTVDLATGRTVGVEALLRWQHPRRGLLRPAEFLPAAEQSELIGLVTSY 352
PRK11359     531 SPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRW 610

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 353 VLDAALASAVHWRQKGIALP-VSVNISARDLHDPSFPDRVDTLLHLHGVPADRLTLEITETTLNSRLYPADAVAKKLRDL 431
PRK11359     611 VIAEACRQLAEWRSQNIHIPaLSVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFKRIQILRDM 690

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 432 GVRLSCDDFGTGTTPLPRLRDLPLAELKIDNTLIAGIVGDDDKRAIVAAVVELGRVFDLTVVAEGIERQDEREVLIRLGC 511
PRK11359     691 GVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHC 770

                        410       420
                 ....*....|....*....|...
gi 117928031 512 TTGQGYYFSPPVPGALIGDVLRP 534
PRK11359     771 RVIQGYFFSRPLPAEEIPGWMSS 793

-1

139666

PRK13561

putative phosphodiesterase; Provisional

false

true

false

651

3e-52

201.92

63.90

6,103,223,31,138,254,98,238,352,11,249,364,208,457,575,15,475,590,49

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 104 HRRASEHAGRDDLTGVANRPALLAALDDTFEdihrRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVRHR 183
PRK13561     224 YEEQNENAMRFPVSDLPNKALLMALLEQVVA----RKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPR 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 184 DVVARLGADEFAVLLRDFNRPEGADAMSRAILRALREPFDVAGLPLTLDVAAGlaVAPRDADTSAE-LLRRAMVALQAAR 262
PRK13561     300 MVLAQISGYDFAIIANGVKEPWHAITLGQQVLTIINERLPIQRIQLRPSCSIG--IAMFYGDLTAEqLYSRAVSAAFTAR 377

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 263 HARSPAVENYRPAHDPAGAERLTLHAELDAALRTGQLVLHYQSTVDLATGRTVGVEALLRWQHPRRGLLRPAEFLPAAEQ 342
PRK13561     378 RKGKNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMRSGKLVSAEALLRMQQPDGSWDLPDGLIDRIES 457

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 343 SELIGLVTSYVLDAALASAVHWRQKGIALPVSVNISARDLHDPSFPDRVDTLLHLHGVPADRLTLEITETTLNSRLYPAD 422
PRK13561     458 CGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAV 537

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 423 AVAKKLRDLGVRLSCDDFGTGTTPLPRLRDLPLAE---LKIDNTLIAGIVGDDdkrAIVAAVVELGRVFDLTVVAEGIER 499
PRK13561     538 AILRPLRNAGVRIALDDFGMGYAGLRQLQHMKSLPidvLKIDKMFVDGLPEDS---SMVAAIIMLAQSLNLQMIAEGVET 614

                        410       420
                 ....*....|....*....|....*
gi 117928031 500 QDEREVLIRLGCTTGQGYYFSPPVP 524
PRK13561     615 EAQRDWLAKAGVGVAQGFLFARPLP 639

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

1e-43

172.97

40.32

12,88,653,10,98,665,3,101,678,24,125,705,16,144,721,61,206,782,14,220,797,63,283,862,37,320,900,38,358,941,5,365,946,5,372,951,152

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031   89 ATPVSQLQGG--GTT----------ATHRRASEHAGRDDLTGVANRPAL---LAALDDTFEDIHRRAAyagLLVVNIRGF 153
PRK09776      654 IAPLSTLDGEniGSVlvfqdvtesrAMLRQLSYSASHDALTGLANRASFekqLREALQTVNSTHQRHA---LVFIDLDRF 730

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031  154 KQINAIVGHSAADQLLTNIAMRLASRVRHRDVVARLGADEFAVLLRDFNRPEgADAMSRAILRALRE-PFDVAGLPLTLD 232
PRK09776      731 KAVNDSAGHAAGDALLRELASLMLSMLRSSDVLARLGGDEFGLLLPDCNVES-ARFIATRIISAINDyRFPWEGRVYRVG 809

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031  233 VAAGLAVAPRDADTSAELLRRAMVALQAARHARSPAVENYRPAHDPAGAER--LTLHAELDAALRTGQLVLHYQSTVDLA 310
PRK09776      810 ASAGITAIDDNNHQASEVMSQADIACYAAKNAGRGRVTVYEPQQAAAHSERreLSLAEQWRSMLEENQLMLQAQEIASPR 889

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031  311 TGRTVGVEAL-LRWQHPRRGLLRPAEFLPAAEQSELIGLVTSYVLDAAL---ASAVHwrQKGIAlpVSVNISARDLHDPS 386
PRK09776      890 IPEARNLWLIsLRLWDCEGEIIDEGAFRPAAEDPALMHALDRWVIHELFqqgARAVA--SKGLS--IAIPLSVASLSSAT 965

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031  387 FPDRVDTLLHLHGVPADRLTLEITETTLNSRLYPADAVAKKLRDLGVRLSCDDFGTGTTPLPRLRDLPLAELKIDNTLIA 466
PRK09776      966 LLPFLLEQLENSPLPPRLLHLEITETALLNHAEAASRLVQKLRLAGCRVVLDDFGRGLSSFNYLKAFMADYLKIDGELCA 1045

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 117928031  467 GIVGDDDKRAIVAAVVELGRVFDLTVVAEGIERQDEREVLIRLGCTTGQGYYFSPPVP 524
PRK09776     1046 NLQGNLMDEMLVSIINGIAQRLGMKTIAGPVELPLTLDTLSGIGVDLAQGYVIGRPQP 1103

-1

138768

PRK11829

biofilm formation regulator HmsP; Provisional

false

true

false

728

2e-43

172.58

56.73

4,112,301,23,136,324,321,457,648,26,486,674,40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 113 RDDLTGVANRPALLAALDDTFEDiHRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVRHRDVVARLGAD 192
PRK11829     302 RFPVTELPNRSLFISLLEKEIAS-STRTDHFHLLVIGIETLQEVSGAMSEAQHQQLLLTIVQRIEQCIDDSDLLAQLSKT 380

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 193 EFAVLLRDFNRPEGADAMSRAILRALREPFDVAGLPLTLDVAAGLAVAPRDADTSAELLRRAMVALQAARHARSPAVENY 272
PRK11829     381 EFAVLARGTRRSFPAMQLARRIMSQVTQPLFFDEITLRPSASIGITRYQAQQDTAESMMRNASTAMMAAHHEGRNQIMVF 460

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 273 RPAHDPAGAERLTLHAELDAALRTGQLVLHYQSTVDLATGRTVGVEALLRWQHPRRGLLRPAEFLPAAEQSELIGLVTSY 352
PRK11829     461 EPHLIEKTHKRLTQENDLLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWCQPDGSYVLPSGFVHFAEEEGMMVPLGNW 540

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 353 VLDAALASAVHWRQKGIALPVSVNISARDLHDPSFPDRVDTLLHLHGVPADRLTLEITETTLNSRLYPADAVAKKLRDLG 432
PRK11829     541 VLEEACRILADWKARGVSLPLSVNISGLQVQNKQFLPHLKTLISHYHIDPQQLLLEITETAQIQDLDEALRLLRELQGLG 620

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 433 VRLSCDDFGTGTTPLPRLRDLPLAE---LKIDNTLIAGIVGDDDKRAIVAAVVElgrVFDLTVVAEGIERQDEREVLIRL 509
PRK11829     621 LLIALDDFGIGYSSLRYLNHLKSLPihmIKLDKSFVKNLPEDDAIARIISCVSD---VLKVRVMAEGVETEEQRQWLLEH 697

                        410
                 ....*....|....*..
gi 117928031 510 GCTTGQGYYFSPPVPGA 526
PRK11829     698 GIQCGQGFLFSPPLPRA 714

-1

34551

COG4943

Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]

Predicted signal transduction protein containing sensor and EAL domains [Signal...

false

true

false

524

2e-41

165.90

45.99

2,282,265,143,426,408,98

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 283 RLTLHAELDAALRTGQLVLHYQSTVDLATGRTVGVEALLRWQHPRRGLLRPAEFLPAAEQSELIGLVTSYVLDAALASAV 362
COG4943      266 YLSPRRRLQRAIERRELCVHYQPIVDLATGKCVGAEALARWPQEDGTVVSPDVFIPLAEESGMIEQITDYVIRNVFRDLG 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 363 HWRQKGIALPVSVNISARDLHDPSFPDRVDTLLHLHGVPADRLTLEITETTLNSRLYPADAVAkKLRDLGVRLSCDDFGT 442
COG4943      346 DLLRQHRDLHVSINLSASDLASPRLIDRLNRKLAQYQVRPQQIALELTERTFADPKKMTPIIL-RLREAGHEIYIDDFGT 424

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 443 GTTPLPRLRDLPLAELKIDNTLIAGIVGDDDKRAIVAAVVELGRVFDLTVVAEGIERQDEREVLIRLGCTTGQGYYFSPP 522
COG4943      425 GYSNLHYLQSLPVDALKIDKSFVDTLGTDSASHLIAPHIIEMAKSLGLKIVAEGVETEEQVDWLRKRGVHYGQGWLFSKA 504


                 ..
gi 117928031 523 VP 524
COG4943      505 LP 506

-1

137979

PRK10551

hypothetical protein; Provisional

false

true

false

518

3e-27

118.62

46.72

7,282,260,70,353,330,14,369,344,6,375,354,12,389,366,17,406,385,11,418,396,106

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 283 RLTLHAELDAALRTGQLVLHYQSTVDLATGRTVGVEALLRWQHPRRGLLRPAEFLPAAEQSELIGLVTSYvLDAALASAV 362
PRK10551     261 RMRPGREILTAIKREQFYVVYQPVVDTQTLRVTGLEVLLRWRHPTAGEIPPDAFINYAEAQKLIVPLTQH-LFELIARDA 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 363 HWRQKgiALPVSV----NISARDLHDPSFpdRVDTLLHLHGVPADRLT--LEITETTLNSRlYPADAVAKKLRDLGVRLS 436
PRK10551     340 AELQK--VLPVGAklgiNIAPAHLHSDSF--KADVQRLLASLPADHFQivLEITERDMLQE-EEALKLFAWLHSQGIEIA 414

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 437 CDDFGTGTTPLPRLRDLPLAELKIDNTLIAGIVGDDDKRAIVAAVVELGRVFDLTVVAEGIERQDEREVLIRLGCTTGQG 516
PRK10551     415 IDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETVTSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLREHGVNFLQG 494


                 ....*...
gi 117928031 517 YYFSPPVP 524
PRK10551     495 YWISRPLP 502

-1

138376

PRK11059

regulatory protein CsrD; Provisional

false

true

false

642

2e-16

83.01

64.49

20,109,226,71,180,298,6,186,305,19,206,324,12,222,336,15,237,354,42,279,399,5,284,405,2,289,407,12,302,419,41,346,460,6,352,469,16,370,485,21,391,507,23,414,533,6,423,539,18,446,557,15,463,572,3,466,578,10,476,592,48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 110 HAGRDDLTGVANRPALLAALDDTFEDIHRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRV-RHRDVV-A 187
PRK11059     227 NAFLDAKTGLGNRLFFDNQLDTLLEDQEKVGAHGVVMLIRLPDFDLLQEELGESQVDELLFELINLLSTFVqRYPGALlA 306

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 188 RLGADEFAVLLRDFNRPEgADAMSRAILRALrepfDVAGLPLTLDVAAGL---AVAPRDADTSAELLRRAMVALQAARHA 264
PRK11059     307 RYSRSDFAVLLPHRSLKE-ADSLASQLLKAV----DSLPPPKMLDRDDFLhigIAAYRSGQSTEQVMEEAEMALRSAQLQ 381

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 265 RSPAVENYRPAHDPA---GAERL-TLhaeLDAALRTGQLVLhYQSTVDLATGRTVGVEALLRWQHPRRGLLRPAEFLPAA 340
PRK11059     382 GGNSWFMYDKAQDPEkgrGSVRWrTL---LEQALVRGGPRL-YQQPVVTRDGQVHHRELMCRIRDGQGNEVRAAEFMPMV 457

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 341 EQSeliGLVTSY---VLDAALASAVHWRQKGiaLPVSVNISARDLHDPSFPDRV-DTLLHLHGVPADRLTLEITETTL-- 414
PRK11059     458 LQC---GLSEQYdrqVIERVLPLLSYWPEES--QNLSINLSVDSLLSRAFQRWLrDTLLQCERSQRKRLIFELAEADVvq 532

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 415 -NSRLYPadaVAKKLRDLGVRLSCDDFGtgttpLPRLRDLPLAELKIDntLIA---GIVGDDDKRA----IVAAVVELGR 486
PRK11059     533 hIDRLRP---VLRMLRGLGCRLAVDQAG-----LTVVSTSYIKELNVE--LIKlhpSLVRNIHQRTenqlFVRSLVGACA 602

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 117928031 487 VFDLTVVAEGIERQDEREVLIRLGCTTGQGYYFSPPVP 524
PRK11059     603 GTETQVFAEGVESREEWQTLQILGVSGGQGDFFASPQP 640

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

3e-16

81.89

40.69

2,99,258,112,211,372,63

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 100 TTATHRRASEHAGRDDLTGVANRPALLAALDDTFEDIHRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASR 179
COG3706      259 LRESLERLQELALVDGLTGLFNRRYFDEHLADLWKRALREGRPLSLLMLDIDDFKEINDTYGHDVGDEVLRQVARRLRQT 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 180 VRHRDVVARLGADEFAVLLRDFNRPEGADAMS--RAILRALREPFDVAGLPLTLDVAAGLAVAPRDADTSAELLRRAMVA 257
COG3706      339 VRGLDLVARYGGEEFAVVLPDTDLEAAIAIAEriRQKINELPFVHELSREPLEVTISIGVAEGKPGEDSIEELLKRADKA 418

                        170
                 ....*....|....*..
gi 117928031 258 LQAARHARSPAVENYRP 274
COG3706      419 LYKAKASGRNRVVVKRA 435

-1

137400

PRK09581

pleD

response regulator PleD; Reviewed

false

true

false

457

1e-14

76.88

34.35

4,108,289,94,203,383,15,218,399,17,235,418,28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 109 EHAGRDDLTGVANRPALLAALDDTFEDIHRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVRHRDVVAR 188
PRK09581     290 EMAVTDGLTGLHNRRYFDMHLKQLIERANERGKPLSLMMLDIDHFKQVNDTYGHDAGDEVLREFAKRLRKNIRGTDLIAR 369

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117928031 189 LGADEFAVLLRDFNrPEGADAMSRAILRAL-REPFDVAGLPLTLDVAA--GLAVAPRDADTSAELLRRAMVALQAARH 263
PRK09581     370 YGGEEFVVVMPDTD-IEVAIAVAERIRRKIaEEPFAISDGKERLNVTVsiGVAELRPSGESIEALIKRADKALYEAKN 446

-1

137615

PRK09966

hypothetical protein; Provisional

false

true

false

407

3e-12

68.51

38.82

3,110,247,33,144,280,82,226,365,40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 111 AGRDDLTGVANRPALLAALDDTFEDIHRRAAYAgLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVRHRDVVARLG 190
PRK09966     248 ALHDPLTGLANRAAFRSGINTLMNNSDARKTSA-LLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEFGGLRHKAYRLG 326

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117928031 191 ADEFAVLLRDFNRPEGADAMSRAILRALREPFDVAG---LPLTLDVAAGLAVAPRDADTSAELLRRAMVALQAARHARS 266
PRK09966     327 GDEFAMVLYDVQSESEVQQICSALTQIFNLPFDLHNghqTTMTLSIGYAMTIEHASAEKLQELADHNMYQAKHQRAEKL 405

-1

137770

PRK10245

adrA

diguanylate cyclase AdrA; Provisional

false

true

false

371

1e-11

66.84

43.94

5,101,199,3,104,203,109,213,314,8,225,322,3,228,326,36

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 102 ATH-RRASEHAGRDDLTGVANRPALLAALDDTFEDIHRRAAYAGLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRV 180
PRK10245     200 AEHkRRLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQITL 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 181 RHRDVVARLGADEFAVLLRDFNRPEGADAMSRA--ILRALREPfdvaGLP-LTLDVAAGLAVAPRDADTSAELLRRAMVA 257
PRK10245     280 RGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVheGLNTLRLP----NAPqVTLRISVGVAPLNPQMSHYREWLKSADLA 355


                 ....*..
gi 117928031 258 LQAARHA 264
PRK10245     356 LYKAKKA 362

-1

137576

PRK09894

hypothetical protein; Provisional

false

true

false

293

1e-11

66.66

50.85

5,112,131,30,144,161,68,214,229,6,220,237,23,244,260,20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 113 RDDLTGVANRPALLAALDDTFEDIHRRAAYagLLVVNIRGFKQINAIVGHSAADQLLTNIAMRLASRVRHRDVVARLGAD 192
PRK09894     132 MDVLTGLPGRRVLDESFDHQLRNREPLNLY--LALLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRPYETVYRYGGE 209

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117928031 193 EFAVLLRDFNRPEGADAMSRaiLRALRE--PFDVAGLPLTLDVAAGLAVAPRDaDTSAELLRRAMVALQAARHA 264
PRK09894     210 EFIIILKAATDEEACRAGER--IRQLIAnqAITHSEGRINITATFGVTRAFPE-EPLDEVIGRADRAMYEGKQA 280

-1

33240

COG3434

Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]

Predicted signal transduction protein containing EAL and modified HD-GYP domains [...

false

true

false

407

4e-04

41.80

27.52

5,400,81,14,414,96,7,424,103,40,468,143,20,492,163,30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117928031 401 PADRLTLEITETTL-NSRLYPAdavAKKLRDLGVRLSCDDFGTGTTPLPRLRDLPLAELKIDNTLiagiVGDDDKRAIVA 479
COG3434       82 PPDKVVIEILEDCPpTEKLLSA---IKELKQKGYLLALDDFIFSNVSEWKPLLPLSDIVKIDFKR----VTFDKARLFDR 154

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 117928031 480 AVVELGRVFdltvVAEGIERQDEREVLIRLGCTTGQGYYFSPP 522
COG3434      155 DLGYINKKF----LAEKVETEEEFEQAKKAGFDLFQGYFFSKP 193

-1

active site	0	10	10	true	133472	cd01949	GGDEF
I-site	1	3	3	true	133472	cd01949	GGDEF