NCBI Conserved Domain Search

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Conserved domains on [gi\|117927828\|ref\|YP_872379.1\|]
diguanylate cyclase [Acidothermus cellulolyticus 11B]

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List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

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of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

133472

cd01949

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as domain of unknown function 1 (DUF1). It is widely present in bacteria and often links to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain has been suggested to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesiveness in bacteria.

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

true

false

true

157

1e-54

208.98

99.36

2,348,0,105,453,109,47

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 349 TDMLTGVANRRTLEENLDRMFAQASRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRSSDLVARYGGE 428
cd01949        1 TDPLTGLPNRRAFEERLERLLARARRSGRPLALLLIDLDHFKQINDTYGHAAGDEVLKEVARRLRSSLRESDLVARLGGD 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117927828 429 EFVVVLPDTDLAGAATAAENLRRRI----FGLDAEPRVTVSLGVATFPLHGGSPDHILSAADAALYQSKSAGRNRV 500
cd01949       81 EFAILLPGTDLEEAEELAERLRKAIeepfFIDGEEIRVTASIGIAEYPEDGEDLEELLRRADKALYQAKRSGRNRV 156

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

110022

pfam00990

GGDEF

GGDEF domain

false

160

1e-47

186.29

100.00

3,346,0,107,453,113,8,461,122,38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 347 AATDMLTGVANRRTLEENLDRMFAQASRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRSSDLVARYG 426
pfam00990      1 AAHDPLTGLPNRRYFEEELEQELQRAQRRQSPLALLLLDLDNFKRINDTYGHAVGDEVLQEVAQRLSSSLRRSDLVARLG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 427 GEEFVVVLPDTDLAGAATAAENLRRRI------FGLDAEPR-VTVSLGVATFPLHGGSPDHILSAADAALYQSKSAGRNR 499
pfam00990     81 GDEFAILLPDTSLEGAQELAERIRRLLaalkipHTLSGLPLyVTISIGIAAYPNDGEDAEDLLKRADQALYQAKNQGRNR 160

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

129356

TIGR00254

GGDEF

diguanylate cyclase (GGDEF) domain

false

165

1e-47

186.00

99.39

2,345,0,114,459,120,44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 346 LAATDMLTGVANRRTLEENLDRMFAQASRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRSSDLVARY 425
TIGR00254      1 QAVRDPLTGLYNRRYLEEMLDSELKRARRFQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 426 GGEEFVVVLPDTDLAGAATAAENLRRRIFGLDAE------PRVTVSLGVATFPLHGGSPDHILSAADAALYQSKSAGRNR 499
TIGR00254     81 GGEEFVVILPGTPLEDALSKAERLRDAINSKPIEvagsetLTVTVSIGVACYPGHGLTLEELLKRADEALYQAKKAGRNR 160


                 ....
gi 117927828 500 VTLA 503
TIGR00254    161 VVVA 164

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

128563

smart00267

GGDEF

diguanylate cyclase

false

163

1e-46

182.83

98.16

2,344,0,108,452,112,48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 345 LLAATDMLTGVANRRTLEENLDRMFAQASRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRSSDLVAR 424
smart00267     1 RLAFRDPLTGLPNRRYFEEELEQELQRAQRQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRPGDLLAR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 425 YGGEEFVVVLPDTDLAGAATAAENLRRR----IFGLDAEPRVTVSLGVATFPLHGGSPDHILSAADAALYQSKSAGRNRV 500
smart00267    81 LGGDEFALLLPETSLEEAIALAERILQQlrepIIIHGIPLYLTISIGVAAYPNPGEDAEDLLKRADTALYQAKKAGRNQV 160

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

32381

COG2199

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction...

false

181

2e-42

168.37

97.24

3,329,2,124,453,130,23,476,154,24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 330 TALALANSWLLEQITLLAATDMLTGVANRRTLEENLDRMFAQASRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRVA 409
COG2199        3 LRLLTRLRKAEERLERLALHDPLTGLPNRRAFEERLERALARARRHGEPLALLLLDLDHFKQINDTYGHAAGDEVLREVA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 410 RALQQGCRSSDLVARYGGEEFVVVLPDTDLAGAATAAENLRRRI----FGLDAEPRVTVSLGVATFPLHGG-SPDHILSA 484
COG2199       83 RRLRSNLREGDLVARLGGDEFAVLLPGTSLEEAARLAERIRAALeepfFLGGEELRVTVSIGVALYPEDGSdDAELLLRR 162

                        170
                 ....*....|....*.
gi 117927828 485 ADAALYQSKSAGRNRV 500
COG2199      163 ADLALYRAKRAGRNRV 178

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

128379

smart00065

GAF

Domain present in phytochromes and cGMP-specific phosphodiesterases.

true

false

149

6e-05

44.29

100.00

6,196,0,7,209,7,45,254,58,23,277,83,30,307,115,16,326,131,18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 197 RLEEALHpadvgrVLVEAVHDDFLAPRAAIVVKSGPGDVILASVKTTPNRLSPAEDRS------IQSVRRERRTWRLGHI 270
smart00065     1 DLEELLQ------TILEELRQLLGADRVLIYLVDEDDRGELVLVAADGLTLPLLGLRYplgeglAGRVAETGRPLNIPDV 74

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117927828 271 DRHRDRW--LAASFPGAQRLLLVPMSAGNNVDGVLVAEH--NARFGSRVDRRVVAMLeryASQTALALANSWLLEQIT 344
smart00065    75 EADPVFAldLLGRYQGVRSFLAVPLVADGELVGVLALHNkdSPRPFTEEDEELLQAL---ANQLAIALANAQLYEELR 149

cl00853

140972

GAF

GAF domain

-1

32385

COG2203

FhlA

FOG: GAF domain [Signal transduction mechanisms]

false

175

7e-04

40.77

96.57

4,186,1,57,243,69,30,273,102,45,319,147,23

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 187 DLLGLARLSQRLEEALHPADVGRVLVEAVHDDFLAPRAAIVVKSGPGDVILASVKTT-----------PNRLSPAEDRSI 255
COG2203        2 EEALLNELAAKIAQDLDLEEILQAALELLAELLGADRGLIYLLDEDGLLDGALVAEAaeagleqlideLFGLVILPACLI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 256 QSVRRERRTWRLGHIDRH---RDRWLAASFPGAQRLLLVPMSAGNNVDGVLVAEHNARFGSRVDRRvVAMLERYASQTAL 332
COG2203       82 GIALREGRPVVVEDILQDprfRDNPLVLLEPPIRSYLGVPLIAQGELLGLLCVHDSEPRRQWSEEE-LELLEELAEQVAI 160

                        170
                 ....*....|
gi 117927828 333 ALANSWLLEQ 342
COG2203      161 AIERARLYEE 170

cl00853

140972

GAF

GAF domain

-1

137400

PRK09581

pleD

response regulator PleD; Reviewed

false

true

false

457

7e-48

187.05

36.76

3,339,284,114,453,402,8,461,413,39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 340 LEQITLLAATDMLTGVANRRTLEENLDRMFAQASRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRSS 419
PRK09581     285 LEQSIEMAVTDGLTGLHNRRYFDMHLKQLIERANERGKPLSLMMLDIDHFKQVNDTYGHDAGDEVLREFAKRLRKNIRGT 364

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 420 DLVARYGGEEFVVVLPDTDLAGAATAAENLRRRI----FGLDAEPR---VTVSLGVATFPLHGGSPDHILSAADAALYQS 492
PRK09581     365 DLIARYGGEEFVVVMPDTDIEVAIAVAERIRRKIaeepFAISDGKErlnVTVSIGVAELRPSGESIEALIKRADKALYEA 444


                 ....*...
gi 117927828 493 KSAGRNRV 500
PRK09581     445 KNTGRNRV 452

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

7e-46

180.12

46.21

5,298,229,20,322,249,14,340,263,113,453,382,7,460,390,40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 299 VDGVLVAEHNARFGSRVDRRvvamLERYASQTALALANswllEQITLLAATDMLTGVANRRTLEENLDRMFAQASRAAQP 378
COG3706      230 NDYITKPIEEGELRARLRRQ----LRRKRYERQLRESL----ERLQELALVDGLTGLFNRRYFDEHLADLWKRALREGRP 301

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 379 ISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRSSDLVARYGGEEFVVVLPDTDLAGAATAAENLRRRI----- 453
COG3706      302 LSLLMLDIDDFKEINDTYGHDVGDEVLRQVARRLRQTVRGLDLVARYGGEEFAVVLPDTDLEAAIAIAERIRQKInelpf 381

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 117927828 454 -FGLDAEP-RVTVSLGVATFPLHGGSPDHILSAADAALYQSKSAGRNRV 500
COG3706      382 vHELSREPlEVTISIGVAEGKPGEDSIEELLKRADKALYKAKASGRNRV 430

-1

137576

PRK09894

hypothetical protein; Provisional

false

true

false

293

4e-34

141.38

55.63

4,343,126,28,373,154,83,456,242,17,474,259,30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 344 TLLAATDMLTGVANRRTLEENLDRMFAQasRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRSSDLVA 423
PRK09894     127 TIRSNMDVLTGLPGRRVLDESFDHQLRN--REPLNLYLALLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRPYETVY 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 424 RYGGEEFVVVLPDTDLAGAATAAENLRRRIFGL-----DAEPRVTVSLGVATFPLhGGSPDHILSAADAALYQSKSAGRN 498
PRK09894     205 RYGGEEFIIILKAATDEEACRAGERIRQLIANQaithsEGRINITATFGVTRAFP-EEPLDEVIGRADRAMYEGKQAGRN 283


                 ....*.
gi 117927828 499 RVTLAG 504
PRK09894     284 RVMFID 289

-1

137770

PRK10245

adrA

diguanylate cyclase AdrA; Provisional

false

true

false

371

3e-27

118.46

47.71

4,328,193,9,339,202,114,453,318,10,463,330,40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 329 QTALALANSwlLEQITLLAATDMLTGVANRRTLEENLDRMFAQASRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRV 408
PRK10245     194 QTATKLAEH--KRRLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVAL 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 409 ARALQQGCRSSDLVARYGGEEFVVVLPDTDLAGAATAAENLRRRI--FGLDAEPRVT--VSLGVATFPLHGGSPDHILSA 484
PRK10245     272 TRQLQITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLntLRLPNAPQVTlrISVGVAPLNPQMSHYREWLKS 351

                        170
                 ....*....|....*....
gi 117927828 485 ADAALYQSKSAGRNRVTLA 503
PRK10245     352 ADLALYKAKKAGRNRTEVA 370

-1

137662

PRK10060

RNase II stability modulator; Provisional

false

true

false

663

3e-24

108.28

23.98

6,340,230,27,369,257,72,441,330,10,451,345,2,454,347,2,457,349,40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 341 EQITLLAATDMLTGVANRRTLEENLDRmfAQASRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRSSD 420
PRK10060     231 ERLRILANTDSITGLPNRNAIQELIDH--AIAQADNNQVGIVYLDLDNFKKVNDAYGHMFGDQLLQDVSLAILSCLEEDQ 308

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 421 LVARYGGEEFVVVLPDTDLAG-AATAAENLRR-----RIfGLdAEPRVTVSLGVATFPLHGGSPDHILSAADAALYQSKS 494
PRK10060     309 TLARLGGDEFLVLASHTSQAAlEAMASRILTRlrlpfRI-GL-IEVYTGCSIGIALSPEHGDDSESLIRSADTAMYTAKE 386


                 ...
gi 117927828 495 AGR 497
PRK10060     387 GGR 389

-1

34606

COG5001

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF...

false

true

false

663

5e-24

107.42

23.83

3,344,225,91,435,320,10,445,331,52

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 345 LLAATDMLTGVANRRTLEENLDRMFAQASRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRSSDLVAR 424
COG5001      226 RLANLDSLTGLPNRRRFFAELDARLAAARQSGRRLVLGVIDLDGFKPVNDAFGHATGDRLLIEVGRRLKAFDGAPILAAR 305

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117927828 425 YGGEEFVVVLP----DTDLAGAATA-AENLRRRIFGLDAEPRVTVSLGVATFPLHGGSPDHILSAADAALYQSKSAGR 497
COG5001      306 LGGDEFALIIPaledDALRVAGARAlCESLQAPYDLRGVRVQVGASIGIAPFPSGADTSEQLFERADYALYHAKQNGK 383

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

8e-24

107.10

15.14

2,338,679,111,449,795,53

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828  339 LLEQITLLAATDMLTGVANRRTLEENLDRMFAQASRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRS 418
PRK09776      680 MLRQLSYSASHDALTGLANRASFEKQLREALQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALLRELASLMLSMLRS 759

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828  419 SDLVARYGGEEFVVVLPDTDLAGAATAAENL-----RRRIFGLDAEPRVTVSLGVATFPLHGGSPDHILSAADAALYQSK 493
PRK09776      760 SDVLARLGGDEFGLLLPDCNVESARFIATRIisainDYRFPWEGRVYRVGASAGITAIDDNNHQASEVMSQADIACYAAK 839


                  ....*....
gi 117927828  494 SAGRNRVTL 502
PRK09776      840 NAGRGRVTV 848

-1

138538

PRK11359

cAMP phosphodiesterase; Provisional

false

true

false

799

1e-15

79.88

22.53

6,320,345,10,330,359,39,372,398,7,380,405,71,451,480,21,474,501,24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 321 AMLERYASQT----ALALANSWLLEQITLLAATDMLTGVANRRTLEENLDRMFaqaSRAAQPIsVVMVDIDHFKHINDTF 396
PRK11359     346 AFIERVADISqhmaALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHNYLDDLV---DKAVSPV-VYLIGVDHIQDVIDSL 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 397 GHQVGDQTLQRVARALQQGCRSSDLVARYGGEEFVVVLPDTDLAGAATAAENLRR----RIFGLDAEPRVTVSLGVATFP 472
PRK11359     422 GYAWADQALLEVVNRFREKLKPDQYLCRIEGTQFVLVSLENDVSNITQIADELRNvvskPIMIDDKPFPLTLSIGISYDV 501

                        170       180
                 ....*....|....*....|....*.
gi 117927828 473 lhGGSPDHILSAADAALYQSKSAGRN 498
PRK11359     502 --GKNRDYLLSTAHNAMDYIRKNGGN 525

-1

137615

PRK09966

hypothetical protein; Provisional

false

true

false

407

3e-11

65.43

48.65

6,307,200,21,328,223,13,341,242,32,374,274,60,434,338,35,469,374,24

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 308 NARFGSRVDRRVVAMLERYAS--QTALALANSWLLE------QITLLAATDMLTGVANRRTLEENLDRMFAQASrAAQPI 379
PRK09966     201 NRNFSRRVSEERIAEFHRFALdfNSLLDEMEEWQLRlqaknaQLLRTALHDPLTGLANRAAFRSGINTLMNNSD-ARKTS 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 380 SVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRSSDLVARYGGEEFVVVL----PDTDLAGAATAAENLRRRIFG 455
PRK09966     280 ALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEFGGLRHKAYRLGGDEFAMVLydvqSESEVQQICSALTQIFNLPFD 359

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 117927828 456 LDAEPRVTVSLGVA-TFPLHGGSPDHILSAADAALYQSK 493
PRK09966     360 LHNGHQTTMTLSIGyAMTIEHASAEKLQELADHNMYQAK 398

-1

138376

PRK11059

regulatory protein CsrD; Provisional

false

true

false

642

1e-04

43.33

23.52

6,346,227,72,418,301,38,457,339,6,463,350,9,473,359,16,492,375,3

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 347 AATDMLTGVANRRTLEENLDRMFAQASRAAQPISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRS--SDLVAR 424
PRK11059     228 AFLDAKTGLGNRLFFDNQLDTLLEDQEKVGAHGVVMLIRLPDFDLLQEELGESQVDELLFELINLLSTFVQRypGALLAR 307

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117927828 425 YGGEEFVVVLPDTDLAGAATAAENLRRRIFGLdAEPRVT-----VSLGVATFPlHGGSPDHILSAADAALyqsKSA 495
PRK11059     308 YSRSDFAVLLPHRSLKEADSLASQLLKAVDSL-PPPKMLdrddfLHIGIAAYR-SGQSTEQVMEEAEMAL---RSA 378

-1

138768

PRK11829

biofilm formation regulator HmsP; Provisional

false

true

false

728

0.004

38.14

21.29

4,351,304,26,378,330,60,441,390,19,460,417,42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927828 352 LTGVANRRTLEENLDRMFAQASRAAQpISVVMVDIDHFKHINDTFGHQVGDQTLQRVARALQQGCRSSDLVARYGGEEFV 431
PRK11829     305 VTELPNRSLFISLLEKEIASSTRTDH-FHLLVIGIETLQEVSGAMSEAQHQQLLLTIVQRIEQCIDDSDLLAQLSKTEFA 383

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117927828 432 VVLPDTDlagAATAAENLRRRIFGLDAEP--------RVTVSLGVATFPLHGGSPDHILSAADAALYQSKSAGRNRVTL 502
PRK11829     384 VLARGTR---RSFPAMQLARRIMSQVTQPlffdeitlRPSASIGITRYQAQQDTAESMMRNASTAMMAAHHEGRNQIMV 459

-1

active site	0	10	10	true	133472	cd01949	GGDEF
I-site	1	3	3	true	133472	cd01949	GGDEF