NCBI Conserved Domain Search

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Conserved domains on [gi\|117927307\|ref\|YP_871858.1\|]
diguanylate cyclase [Acidothermus cellulolyticus 11B]

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List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

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of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

133472

cd01949

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as domain of unknown function 1 (DUF1). It is widely present in bacteria and often links to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain has been suggested to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesiveness in bacteria.

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

true

false

true

157

2e-42

169.31

100.00

4,400,0,20,420,24,87,508,111,18,526,130,27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 401 RDALTGLANRRALDMALEAL----AKSDTVSSLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAILRGECREDDVVARFGGD 476
cd01949        1 TDPLTGLPNRRAFEERLERLlaraRRSGRPLALLLIDLDHFKQINDTYGHAAGDEVLKEVARRLRSSLRESDLVARLGGD 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 117927307 477 EFVLVLHGAPRKTGIRVGERIRSAVKAFSWEkIAPDLRVSVSIGVAEFQP-GMDLSEALLTADSALYAAKQQGRDRVA 553
cd01949       81 EFAILLPGTDLEEAEELAERLRKAIEEPFFI-DGEEIRVTASIGIAEYPEdGEDLEELLRRADKALYQAKRSGRNRVV 157

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

128563

smart00267

GGDEF

diguanylate cyclase

false

163

2e-37

152.40

100.00

4,396,0,16,412,20,89,502,109,23,525,133,30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 397 HEALRDALTGLANRRA----LDMALEALAKSDTVSSLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAILRGECREDDVVAR 472
smart00267     1 RLAFRDPLTGLPNRRYfeeeLEQELQRAQRQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRPGDLLAR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 473 FGGDEFVLVLHGAPRKTGIRVGERIRSAVkAFSWEKIAPDLRVSVSIGVAEFQ-PGMDLSEALLTADSALYAAKQQGRDR 551
smart00267    81 LGGDEFALLLPETSLEEAIALAERILQQL-REPIIIHGIPLYLTISIGVAAYPnPGEDAEDLLKRADTALYQAKKAGRNQ 159


                 ....
gi 117927307 552 VAAA 555
smart00267   160 VAVY 163

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

110022

pfam00990

GGDEF

GGDEF domain

false

160

1e-35

146.62

100.00

4,398,0,14,412,18,90,502,110,22,524,133,27

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 399 ALRDALTGLANRRA----LDMALEALAKSDTVSSLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAILRGECREDDVVARFG 474
pfam00990      1 AAHDPLTGLPNRRYfeeeLEQELQRAQRRQSPLALLLLDLDNFKRINDTYGHAVGDEVLQEVAQRLSSSLRRSDLVARLG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 475 GDEFVLVLHGAPRKTGIRVGERIRSAVK--AFSWEKIAPDLRVSVSIGVAEF-QPGMDLSEALLTADSALYAAKQQGRDR 551
pfam00990     81 GDEFAILLPDTSLEGAQELAERIRRLLAalKIPHTLSGLPLYVTISIGIAAYpNDGEDAEDLLKRADQALYQAKNQGRNR 160

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

32381

COG2199

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]

c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction...

false

181

1e-35

146.42

100.00

4,379,0,33,412,37,96,509,133,26,535,161,20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 380 MVRMQMLELAAENERVEHEALRDALTGLANRRA----LDMALEALAKSDTVSSLLFVDLDDFKTTNDSFSHTVGDEVLRS 455
COG2199        1 ALLRLLTRLRKAEERLERLALHDPLTGLPNRRAfeerLERALARARRHGEPLALLLLDLDHFKQINDTYGHAAGDEVLRE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 456 IAAILRGECREDDVVARFGGDEFVLVLHGAPRKTGIRVGERIRSAVKAFSWEKiAPDLRVSVSIGVAEFQPGMDLSEALL 535
COG2199       81 VARRLRSNLREGDLVARLGGDEFAVLLPGTSLEEAARLAERIRAALEEPFFLG-GEELRVTVSIGVALYPEDGSDDAELL 159

                        170       180
                 ....*....|....*....|..
gi 117927307 536 --TADSALYAAKQQGRDRVAAA 555
COG2199      160 lrRADLALYRAKRAGRNRVVVF 181

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

129356

TIGR00254

GGDEF

diguanylate cyclase (GGDEF) domain

false

165

1e-35

146.33

98.79

5,398,1,20,418,24,9,427,34,80,507,115,29,536,145,19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 399 ALRDALTGLANRRALDMALE---ALAKSDTVS-SLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAILRGECREDDVVARFG 474
TIGR00254      2 AVRDPLTGLYNRRYLEEMLDselKRARRFQRSfSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRYG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 475 GDEFVLVLHGAPRKTGIRVGERIRSAVKAFSWE-KIAPDLRVSVSIGVAEFQPGMDLSEALLT-ADSALYAAKQQGRDRV 552
TIGR00254     82 GEEFVVILPGTPLEDALSKAERLRDAINSKPIEvAGSETLTVTVSIGVACYPGHGLTLEELLKrADEALYQAKKAGRNRV 161


                 ...
gi 117927307 553 AAA 555
TIGR00254    162 VVA 164

cl00291

140583

GGDEF

Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue...

-1

137400

PRK09581

pleD

response regulator PleD; Reviewed

false

true

false

457

1e-37

153.15

35.89

4,398,291,29,427,324,74,501,400,35,536,436,19

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 399 ALRDALTGLANRRALDMALEALAKSDTVS----SLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAILRGECREDDVVARFG 474
PRK09581     292 AVTDGLTGLHNRRYFDMHLKQLIERANERgkplSLMMLDIDHFKQVNDTYGHDAGDEVLREFAKRLRKNIRGTDLIARYG 371

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 475 GDEFVLVLHGAPRKTGIRVGERIRSAV--KAFSWEKIAPDLRVSVSIGVAEFQPGMDLSEALLT-ADSALYAAKQQGRDR 551
PRK09581     372 GEEFVVVMPDTDIEVAIAVAERIRRKIaeEPFAISDGKERLNVTVSIGVAELRPSGESIEALIKrADKALYEAKNTGRNR 451


                 ....
gi 117927307 552 VAAA 555
PRK09581     452 VVAL 455

-1

33501

COG3706

PleD

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]

Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal...

false

true

false

435

8e-36

146.99

39.54

4,387,258,40,427,302,75,502,379,34,536,414,16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 388 LAAENERVEHEALRDALTGLANRRALDMALEALAKSDTVS----SLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAILRGE 463
COG3706      259 LRESLERLQELALVDGLTGLFNRRYFDEHLADLWKRALREgrplSLLMLDIDDFKEINDTYGHDVGDEVLRQVARRLRQT 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 464 CREDDVVARFGGDEFVLVLHGAPRKTGIRVGERIRSAVK--AFSWEKIAPDLRVSVSIGVAEFQPGMDLSEALLT-ADSA 540
COG3706      339 VRGLDLVARYGGEEFAVVLPDTDLEAAIAIAERIRQKINelPFVHELSREPLEVTISIGVAEGKPGEDSIEELLKrADKA 418

                        170
                 ....*....|..
gi 117927307 541 LYAAKQQGRDRV 552
COG3706      419 LYKAKASGRNRV 430

-1

137576

PRK09894

hypothetical protein; Provisional

false

true

false

293

3e-28

121.74

59.73

3,385,111,15,400,131,19,419,152,134

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 386 LELAAENERVEHEAL-----RDALTGLANRRALDMALEA--LAKSDTVSSLLFVDLDDFKTTNDSFSHTVGDEVLRSIAA 458
PRK09894     112 LSFTAALTDYKIYLLtirsnMDVLTGLPGRRVLDESFDHqlRNREPLNLYLALLDIDRFKLVNDTYGHLIGDVVLRTLAT 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 459 ILRGECREDDVVARFGGDEFVLVLHGAPRKTGIRVGERIRSAVKAFSWEKIAPDLRVSVSIGVAEFQPGMDLSEALLTAD 538
PRK09894     192 YLASWTRPYETVYRYGGEEFIIILKAATDEEACRAGERIRQLIANQAITHSEGRINITATFGVTRAFPEEPLDEVIGRAD 271

                        170
                 ....*....|....*
gi 117927307 539 SALYAAKQQGRDRVA 553
PRK09894     272 RAMYEGKQAGRNRVM 286

-1

137770

PRK10245

adrA

diguanylate cyclase AdrA; Provisional

false

true

false

371

4e-23

104.98

46.63

4,386,197,31,417,232,89,507,321,22,529,344,26

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 387 ELAAENERVEHEALRDALTGLANRRALDMAL----EALAKSDTVSSLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAILRG 462
PRK10245     198 KLAEHKRRLQVMSTRDGMTGVYNRRHWETMLrnefDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQI 277

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 463 ECREDDVVARFGGDEFVLVLHGAPRKTGIRVGERIRSAVKAFSWeKIAPDLRVSVSIGVAEFQPGMD-LSEALLTADSAL 541
PRK10245     278 TLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRL-PNAPQVTLRISVGVAPLNPQMShYREWLKSADLAL 356

                        170
                 ....*....|....
gi 117927307 542 YAAKQQGRDRVAAA 555
PRK10245     357 YKAKKAGRNRTEVA 370

-1

137515

PRK09776

putative sensor protein; Provisional

false

true

false

1116

1e-22

103.25

14.43

5,396,685,14,410,703,93,503,798,4,509,802,15,524,818,28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307  397 HEALRDALTGLANR----RALDMALEALAKSDTVSSLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAILRGECREDDVVAR 472
PRK09776      686 YSASHDALTGLANRasfeKQLREALQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALLRELASLMLSMLRSSDVLAR 765

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307  473 FGGDEFVLVLHGAPRKTGIRVGERIRSAVKA--FSWEkiAPDLRVSVSIGVAEF-QPGMDLSEALLTADSALYAAKQQGR 549
PRK09776      766 LGGDEFGLLLPDCNVESARFIATRIISAINDyrFPWE--GRVYRVGASAGITAIdDNNHQASEVMSQADIACYAAKNAGR 843


                  ...
gi 117927307  550 DRV 552
PRK09776      844 GRV 846

-1

34606

COG5001

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]

Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF...

false

true

false

663

3e-21

98.56

27.15

4,378,203,23,401,230,11,412,245,124,536,370,13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 379 VMVRMQMLELAAENERVEHEALR----DALTGLANRRA----LDMALEALAKSDTVSSLLFVDLDDFKTTNDSFSHTVGD 450
COG5001      204 VQSQVTLTQRAEETRRLSDENDRlanlDSLTGLPNRRRffaeLDARLAAARQSGRRLVLGVIDLDGFKPVNDAFGHATGD 283

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 451 EVLRSIAAILRGECREDDVVARFGGDEFVLVLHGAPRKTGIRVGERIRSAVKAFSWEKIAPDLRVSVSIGVAEFQPGMDL 530
COG5001      284 RLLIEVGRRLKAFDGAPILAARLGGDEFALIIPALEDDALRVAGARALCESLQAPYDLRGVRVQVGASIGIAPFPSGADT 363

                        170       180
                 ....*....|....*....|
gi 117927307 531 SEALLT-ADSALYAAKQQGR 549
COG5001      364 SEQLFErADYALYHAKQNGK 383

-1

137662

PRK10060

RNase II stability modulator; Provisional

false

true

false

663

1e-19

93.25

24.74

8,392,225,9,401,239,12,413,252,14,427,267,51,478,319,6,484,328,23,512,351,12,524,364,25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 393 ERVEHEALR-----DALTGLANRRAL-DMALEALAKSDTVS-SLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAILRGECR 465
PRK10060     226 ERRAQERLRilantDSITGLPNRNAIqELIDHAIAQADNNQvGIVYLDLDNFKKVNDAYGHMFGDQLLQDVSLAILSCLE 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 466 EDDVVARFGGDEF-VLVLHG---APRKTGIRVGERIRSAVKAFSWEkiapdLRVSVSIGVAEF-QPGMDLSEALLTADSA 540
PRK10060     306 EDQTLARLGGDEFlVLASHTsqaALEAMASRILTRLRLPFRIGLIE-----VYTGCSIGIALSpEHGDDSESLIRSADTA 380


                 ....*....
gi 117927307 541 LYAAKQQGR 549
PRK10060     381 MYTAKEGGR 389

-1

137615

PRK09966

hypothetical protein; Provisional

false

true

false

407

1e-13

73.13

41.77

7,385,234,41,426,278,65,494,343,7,501,351,6,507,360,15,522,378,10,535,388,16

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 386 LELAAENERVEHEALRDALTGLANRRALDMALEALAKSDTV---SSLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAILRG 462
PRK09966     235 LRLQAKNAQLLRTALHDPLTGLANRAAFRSGINTLMNNSDArktSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAE 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 463 ECREDDVVARFGGDEFVLVLHGAPRKTGIrvgERIRSAV-KAFSWE---KIAPDLRVSVSIGVA---EFQPGMDLSEall 535
PRK09966     315 FGGLRHKAYRLGGDEFAMVLYDVQSESEV---QQICSALtQIFNLPfdlHNGHQTTMTLSIGYAmtiEHASAEKLQE--- 388

                        170
                 ....*....|....*.
gi 117927307 536 TADSALYAAKQQGRDR 551
PRK09966     389 LADHNMYQAKHQRAEK 404

-1

138538

PRK11359

cAMP phosphodiesterase; Provisional

false

true

false

799

4e-11

65.25

20.78

5,384,357,9,393,370,110,506,480,6,512,488,10,523,498,25

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 385 MLELAAENE----RVEHEALRDALTGLANRRALDMALEALAKSDTVSSLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAIL 460
PRK11359     358 MAALALEQEksrqHIEQLIQFDPMTGLPNRNNLHNYLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRF 437

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 461 RGECREDDVVARFGGDEFVLVLHGAPRKTGIRVGERIRSAVKAfswEKIAPD--LRVSVSIGVAeFQPGMDLSEALLTAD 538
PRK11359     438 REKLKPDQYLCRIEGTQFVLVSLENDVSNITQIADELRNVVSK---PIMIDDkpFPLTLSIGIS-YDVGKNRDYLLSTAH 513

                        170
                 ....*....|
gi 117927307 539 SALYAAKQQG 548
PRK11359     514 NAMDYIRKNG 523

-1

139666

PRK13561

putative phosphodiesterase; Provisional

false

true

false

651

7e-07

50.92

25.50

4,387,219,101,488,321,15,503,337,7,512,344,41

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 388 LAAENERVEHEALRDALTGLANRRALDMALEALAKSDTVSSLLFVDLDDFKTTNDSFSHTVGDEVLRSIAAILRGECRED 467
PRK13561     220 LQRHYEEQNENAMRFPVSDLPNKALLMALLEQVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPR 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 468 DVVARFGGDEFVLVLHGAPRK-TGIRVGERIRSAVKA-FSWEKIApdLRVSVSIGVAEFQPGMDLSEALLTADSALYAAK 545
PRK13561     300 MVLAQISGYDFAIIANGVKEPwHAITLGQQVLTIINErLPIQRIQ--LRPSCSIGIAMFYGDLTAEQLYSRAVSAAFTAR 377


                 ....*...
gi 117927307 546 QQGRDRVA 553
PRK13561     378 RKGKNQIQ 385

-1

138376

PRK11059

regulatory protein CsrD; Provisional

false

true

false

642

1e-04

43.33

23.68

8,401,230,19,420,253,33,453,290,8,464,298,6,470,305,12,485,317,19,506,336,10,516,350,32

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 402 DALTGLANRRALDMALEAL----AKSDTVSSLLFVDLDDFKTTNDSFSHTVGDEVL----RSIAAILRgecREDDVV-AR 472
PRK11059     231 DAKTGLGNRLFFDNQLDTLledqEKVGAHGVVMLIRLPDFDLLQEELGESQVDELLfeliNLLSTFVQ---RYPGALlAR 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927307 473 FGGDEFVLVLhgaPRKTGIRVGERIRSAVKAFswEKIAPDLRVS----VSIGVAEFQPGMDLSEALLTADSALYAAKQQG 548
PRK11059     308 YSRSDFAVLL---PHRSLKEADSLASQLLKAV--DSLPPPKMLDrddfLHIGIAAYRSGQSTEQVMEEAEMALRSAQLQG 382

-1

active site	0	10	10	true	133472	cd01949	GGDEF
I-site	1	3	3	true	133472	cd01949	GGDEF