NCBI Conserved Domain Search

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Conserved domains on [gi\|117927300\|ref\|YP_871851.1\|]
histidine kinase [Acidothermus cellulolyticus 11B]

Graphical summary show options »	Show site features Horizontal zoom: ×	?



List of domain hits		?

References:

Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.

Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.

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of the residues that compose this conserved feature have been mapped to the query sequence.

Click on the triangle to view details about the feature, including a multiple sequence alignment of your query sequence and the protein sequences used to curate the domain model, where hash marks (#) above the aligned sequences show the location of the conserved feature residues.

The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions. Click on the triangle for interactive 3D structure viewing options.

This image shows a graphical summary of conserved domains identified on the query sequence. The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits (labeled illustration) or all hits (labeled illustration).
Domains are color coded according to superfamilies to which they have been assigned. Hits with scores that pass a domain-specific threshold (specific hits) are drawn in bright colors. Others (non-specific hits) and superfamily placeholders are drawn in pastel colors.
if a domain or superfamily has been annotated with functional sites (conserved features), they are mapped to the query sequence and indicated through sets of triangles with the same color and shade of the domain or superfamily that provides the annotation.
Mouse over the colored bars or triangles to see descriptions of the domains and features. click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.

The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores. Click on the PssmId to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.

To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page, or click on the triangles, if present, that represent functional sites (conserved features) mapped to the query sequence.

Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence. (labeled illustration)
Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance. (labeled illustration)
Four types of hits can be shown, as available, for each region on the query sequence:

specific hits meet or exceed a domain-specific e-value threshold (illustrated example) and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits meet or exceed the RPS-BLAST threshold for statistical significance (default E-value cutoff of 0.01, or an E-value selected by user via the advanced search options)
the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains

The CD-Search help document provides more detail about the tool and its features.

Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool (CDART).

Modify your query to search against a different database and/or use advanced search options

28956

cd00075

HATPase_c

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for...

true

false

true

103

4e-20

94.23

100.00

3,244,0,27,274,27,30,306,57,46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 245 LATAVTNLVENAIVYSSRGGRVGVGARervTPEGRIVEIAVSDNGIGIARADQERIFERFyrVDPGRSRATGGTGLGLAI 324
cd00075        1 LQQVLLNLLSNAIKHTPEGGGRITISV---ERDGDHLEIRVEDNGPGIPEEDLERIFERF--SDGSRSRKGGGTGLGLSI 75

                         90       100
                 ....*....|....*....|....*...
gi 117927300 325 VKHIVNNHGGRISVWSKPGTGSTFTLHL 352
cd00075       76 VKKLVELHGGRIEVESEPGGGTTFTITL 103

cl00075

140416

HATPase_c

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for...

119399

cd00082

HisKA

Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.

Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are...

true

false

true

9e-12

66.47

92.31

1,131,5,60

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 132 DFIANVSHELKTPVGAMLLLAEAIRDAQDDPAALTHFIDRLIHEANRLSRLVKELIDLSR 191
cd00082        6 EFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65

cl00080

140419

HisKA

Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are...

128669

smart00387

HATPase_c

Histidine kinase-like ATPases

false

111

4e-27

117.36

98.20

3,239,0,21,264,21,45,310,66,43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 240 GDRRQLATAVTNLVENAIVYSsrggRVGVGARERVTPEGRIVEIAVSDNGIGIARADQERIFERFYRVDPgRSRATGGTG 319
smart00387     1 GDPDRLRQVLSNLLDNAIKYT----PEGGRITVTLERDGDHLEITVEDNGPGIPPEDLEKIFEPFFRTDG-RSRKIGGTG 75

                         90       100       110
                 ....*....|....*....|....*....|....
gi 117927300 320 LGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
smart00387    76 LGLSIVKKLVELHGGEISVESEPGGGTTFTITLP 109

cl00075

140416

HATPase_c

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for...

-1

111420

pfam02518

HATPase_c

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase

false

111

5e-24

107.03

100.00

3,239,0,21,264,21,42,307,63,48

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 240 GDRRQLATAVTNLVENAIVYSsrggRVGVGARERVTPEGRIVEIAVSDNGIGIARADQERIFERFYRvDPGRSRATGGTG 319
pfam02518      1 GDEDRLRQVLSNLLDNAIKHA----PAGGEITVTLEREGGRLRITVEDNGPGIPPEDLEKIFEPFYR-DGSDSRKVGGTG 75

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 117927300 320 LGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLPAP 355
pfam02518     76 LGLSIVKKLVELHGGTITVESEPGGGTTFTLTLPLE 111

cl00075

140416

HATPase_c

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for...

-1

109563

pfam00512

HisKA

His Kinase A (phosphoacceptor) domain

false

6e-11

63.74

95.45

2,131,3,26,158,29,37

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117927300 132 DFIANVSHELKTPVGAMLLLAEAIRDaQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGG 195
pfam00512      4 EFLANLSHELRTPLTAIRGYLELLLD-TELSEEQREYLETILRSAERLLRLINDLLDLSRIEAG 66

cl00080

140419

HisKA

Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are...

-1

128670

smart00388

HisKA

His Kinase A (phosphoacceptor) domain

false

1e-10

62.98

95.45

2,131,3,27,159,30,36

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117927300 132 DFIANVSHELKTPVGAMLLLAEAIRDAqDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGG 195
smart00388     4 EFLANLSHELRTPLTAIRGYLELLEDT-ELSEEQREYLETILRSAERLLRLINDLLDLSRIEAG 66

cl00080

140419

HisKA

Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are...

-1

134915

PRK03660

anti-sigma F factor; Provisional

false

146

0.001

39.55

63.70

5,246,41,14,261,55,38,301,93,12,317,105,9,330,114,20

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 247 TAVTNLVENAIVYSsRGGRVGVGARERVTPEGRIVEIAVSDNGIGIARADQERifERFYRVDPGRSRatggTGLGLAIVK 326
PRK03660      42 TAVSEAVTNAIIHG-YENNPDGIVYIEAEIEDEELEITVRDEGKGIEDVEEAR--QPLFTTKPELER----SGMGFTFME 114

                         90       100
                 ....*....|....*....|....
gi 117927300 327 hivnNHGGRISVWSKPGTGSTFTL 350
PRK03660     115 ----SFMDEVEVESEPGKGTTIRM 134

cl00075

140416

HATPase_c

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for...

-1

130980

TIGR01925

spIIAB

anti-sigma F factor

false

137

0.003

37.98

70.07

5,243,38,17,261,55,31,294,86,19,317,105,14,335,119,15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 244 QLATAVTNLVENAIVYSsRGGRVGVGARERVTPEGRIVEIAVSDNGIGIarADQERIFERFYRVDPGRSRatggTGLGLA 323
TIGR01925     39 DIKTAVSEAVTNAIIHG-YEENCEGVVYISATIEDHEVYITVRDEGIGI--ENLEEAREPLYTSKPELER----SGMGFT 111

                         90       100
                 ....*....|....*....|....*..
gi 117927300 324 IVKHIVNNhggrISVWSKPGTGSTFTL 350
TIGR01925    112 VMENFMDD----VSVDSEKEKGTKIIM 134

cl00075

140416

HATPase_c

Histidine kinase-like ATPases; This family includes several ATP-binding proteins for...

-1

132011

TIGR02966

phoR_proteo

phosphate regulon sensor kinase PhoR

false

true

false

333

1e-51

198.97

72.67

5,107,91,50,157,142,102,274,244,4,278,249,2,280,261,72

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 108 LDSKRVVLLVTDVEESRRVEAVRRDFIANVSHELKTPVGAMLLLAEAIRD-AQDDPAALTHFIDRLIHEANRLSRLVKEL 186
TIGR02966     92 YGEEQKLLVARDVTRLRRLEQMRRDFVANVSHELRTPLTVLRGYLETLADgPDEDPEEWNRALEIMLEQSQRMQSLVEDL 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 187 IDLSRLQGGDPLPELSEVRVSDIVSDAVEPLHVRAEAAGIRLEVAIPANLCVLGDRRQLATAVTNLVENAIVYssrggrv 266
TIGR02966    172 LTLSRLESAASPLEDEPVDMPALLDHLRDEAEALSQGKNHQITFEIDGGVDVLGDEDELRSAFSNLVSNAIKY------- 244

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 267 gvgarervTPEG-RI----------VEIAVSDNGIGIARADQERIFERFYRVDPGRSRATGGTGLGLAIVKHIVNNHGGR 335
TIGR02966    245 --------TPEGgTItvrwrrdgggAEFSVTDTGIGIAPEHLPRLTERFYRVDKSRSRDTGGTGLGLAIVKHVLSRHHAR 316

                        250
                 ....*....|....*..
gi 117927300 336 ISVWSKPGTGSTFTLHL 352
TIGR02966    317 LEIESELGKGSTFSFIF 333

-1

30987

COG0642

BaeS

Signal transduction histidine kinase [Signal transduction mechanisms]

false

true

false

336

7e-38

153.40

63.99

5,131,116,33,166,149,32,198,182,71,274,253,38,316,291,40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 132 DFIANVSHELKTPVGAMLLLAEAIRDAQDDPAAltHFIDRLIHEANRLSRLVKELIDLSRLQGGDPL-PELSEVRVSDIV 210
COG0642      117 EFLANISHELRTPLTAIRGLLELLLEGLLDPQR--ELLEIIEEEAERLLRLVNDLLDLSRLEAGTKLkLLLELVDLAELL 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 211 SDAVEPLHVRAEAAGIRLEVAIPANLCVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGarervTPEGRIVEIAVSDNGI 290
COG0642      195 EEVVRLLAPLAQEKGIELAVDLPELPYVLGDPERLRQVLVNLLSNAIKYTPGGEITISV-----RQDDEQVTISVEDTGP 269

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117927300 291 GIARADQERIFERFYRVDPGRSratgGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLPAPA 356
COG0642      270 GIPEEELERIFEPFFRTDKSRS----GTGLGLAIVKRIVELHGGTISVESEPGKGTTFTIRLPLAP 331

-1

34607

COG5002

VicK

Signal transduction histidine kinase [Signal transduction mechanisms]

false

true

false

459

9e-36

146.23

48.15

5,131,226,26,157,253,61,218,315,17,235,333,37,276,370,77

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 132 DFIANVSHELKTPVGAMLLLAEAIRD-AQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIV 210
COG5002      227 EFVANVSHELRTPLTSMKSYLEALEEgAWEDKEIAPRFLRVTLNETERMIRLVNDLLQLSRMDNARYQLNKEWINFTAFL 306

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 211 SDAVEPLH-VRAEAAGIRLEVAIPAN-LCVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARErvtpEGRIVEIAVSDN 288
COG5002      307 NEIINRFEmILKKETIARFVRDIPKQdIWVEIDPDKMTQVLDNIISNALKYSPDGGRITVSVKQ----RETWVEISISDQ 382

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 117927300 289 GIGIARADQERIFERFYRVDPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
COG5002      383 GLGIPKEDLEKIFDRFYRVDKARSRKMGGTGLGLAIAKEIVQAHGGRIWAESEEGKGTTFSFTLP 447

-1

138336

PRK11006

phoR

phosphate regulon sensor protein; Provisional

false

true

false

431

9e-35

142.93

50.58

4,131,205,64,196,269,64,262,333,16,280,349,74

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 132 DFIANVSHELKTPVGAMLLLAEAIRDAQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGGdPLPELSEVRVSDIVS 211
PRK11006     206 NFFANVSHELRTPLTVLQGYLEMMEEQPLEGPMREKALHTMREQTQRMEGLVKQLLTLSKIEAA-PTHLLNEKVDVPMML 284

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 212 DAVEPLHVRAEAAGIRLEVAIPANLCVLGDRRQLATAVTNLVENAIVYSsrGGRVGVGARERVTPEGriVEIAVSDNGIG 291
PRK11006     285 RVLEREAQTLSQKKHTITFEVDDSLKVLGNEDQLRSAISNLVYNAVNHT--PEGTHITVRWQRVPHG--AEFSVEDNGPG 360

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 117927300 292 IARADQERIFERFYRVDPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLPA 354
PRK11006     361 IAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALNHHDSRLEIESTVGKGTRFSFVLPE 423

-1

32387

COG2205

KdpD

Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]

false

true

false

890

3e-31

131.14

24.49

6,132,662,35,167,699,48,217,747,22,239,770,33,276,803,31,309,834,46

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 133 FIANVSHELKTPVGAMLLLAEAIRDAQDDPAALTH--FIDRLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIV 210
COG2205      663 LLASISHDLRTPLTAIMGAAETLLLDGEALSPEDRaeLLSSIREESERLTRLVTNLLDMTRLQSGGVNLKLDWVLVEEVV 742

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 211 SDAVEplHVRAEAAGIRLEVAIPANLCVL-GDRRQLATAVTNLVENAIVYSSRGGRVGVGARErvtpEGRIVEIAVSDNG 289
COG2205      743 GEALQ--RLRKRFTGHKIVVSVPVDLPLIhVDSPLIEQVLINLLENALKYAPPGSEIRINAGV----ERENVVFSVIDEG 816

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117927300 290 IGIARADQERIFERFYRVdpGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLPAP 355
COG2205      817 PGIPEGELERIFDKFYRG--NKESATRGVGLGLAICRGIVEAHGGTISAENNPGGGAIFVFTLPVE 880

-1

138403

PRK11100

sensory histidine kinase CreC; Provisional

false

true

false

475

1e-28

122.66

44.42

6,138,264,19,158,283,76,235,359,25,264,384,41,305,428,7,316,435,40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 139 HELKTPVGAMLLLAEAIRDaQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIVSDAVEPLH 218
PRK11100     265 HELKSPLAAIRGAAELLQE-DPPPEDRQRFTGNILAQSARLQQLIDRLLELARLEQRQELEVLEPVALAALLEELVEARE 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 219 VRAEAAGIRLEVAIPAnLCVLGDRRQLATAVTNLVENAIVYSsrggRVGVGARERVTPEGRIVEIAVSDNGIGIARADQE 298
PRK11100     344 AQAAAKGITLRLRPDD-AAVLGDPFLLRQALGNLLDNAIDFT----PEGGTITLSAERDGEQVALSVEDSGPGIPDYALP 418

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117927300 299 RIFERFY---RVDPGRSratgGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLPAPA 356
PRK11100     419 RIFERFYslpRPANGRK----STGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPRHF 475

-1

137312

PRK09470

cpxA

two-component sensor protein; Provisional

false

true

false

461

1e-27

119.31

45.55

7,133,246,12,146,258,8,154,267,12,170,279,28,199,307,31,230,339,30,266,369,87

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 134 IANVSHELKTPVgAMLLLAEA-IRDAQDDPAALThfidRLIHEANRLSRLVKELIDLSRLQGGDPLpELSEVRVSDIVSD 212
PRK09470     247 LSDISHELRTPL-TRLQLATAlLRRRQGESKELE----RIETEAQRLDSMINDLLVLSRNQVKNHL-VRETIKANSLWSE 320

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 213 AVEPLHVRAEAAGIRLEV-AIPANLCVLGDRRQLATAVTNLVENAIVYSsrggrvGVGARERVTPEGRIVEIAVSDNGIG 291
PRK09470     321 VLEDAAFEAEQMGKSLTVnQPPGPWPINGNPNALESALENIVRNALRYS------HTKIEVGFSVDKDGLTITVDDDGPG 394

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 117927300 292 IARADQERIFERFYRVDPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
PRK09470     395 VPEEEREQIFRPFYRVDEARDRESGGTGLGLAIVENAIQQHRGWVKAEDSPLGGLRLTIWLP 456

-1

137202

PRK09303

adaptive-response sensory kinase; Validated

false

true

false

378

2e-27

118.52

58.73

6,133,152,29,162,183,16,178,203,58,236,262,41,280,303,28,310,331,43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 134 IANVSHELKTPVGAMLLLAEAIRDAQDDP--AALTHFIDRLIHEANR----LSRLVKELIDLSRLQGGDPLPELSEVRVS 207
PRK09303     153 LAMLAHDLRTPLTAASLAVETLELGQIDPseELSPALIEQLQDQARRqleeIERLITDLLEVGRTRWEALQFNPQKLDLG 232

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 208 DIVSDAVEPLHVRAEAAGIRLEVAIPANL-CVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARERVTPEgriVEIAVS 286
PRK09303     233 SLCQEVILELEKRWLAKSLEIQTDIPSDLpSVYADQRRIRQVLLNLLDNAIKYTPEGGTITLTMLHRTTQK---VQVSIC 309

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117927300 287 DNGIGIARADQERIFERFYRVDpgRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
PRK09303     310 DTGPGIPEEEQERIFEDRVRLP--RDEGTEGYGIGLSVCRRIVEVHYGQIWVDSEPGQGSCFHFTLP 374

-1

130453

TIGR01386

cztS_silS_copS

heavy metal sensor kinase

false

true

false

457

5e-27

117.10

47.05

4,131,242,100,233,342,39,276,381,68,345,449,8

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 132 DFIANVSHELKTPVGAMLLLAEAIRDAQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIVS 211
TIGR01386    243 QFSADLAHELRTPLTNLLGQTQVALSQPRTGEEYREVLESNLEELERLSRMVSDMLFLARADNGQLALERVRLDLAAELA 322

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 212 DAVEPLHVRAEAAGIRLEVAipANLCVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARErvtpEGRIVEIAVSDNGIG 291
TIGR01386    323 KVAEYFEPLAEERGVRIRVE--GEGLVRGDPQMFRRAISNLLSNALRHTPDGGTITVRIER----RSDEVRVSVSNPGPG 396

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 117927300 292 IARADQERIFERFYRVDPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTgSTFTLHLP 353
TIGR01386    397 IPPEHLSRLFDRFYRVDPARSNSGEGTGLGLAIVRSIMEAHGGRASAESPDGK-TRFILRFP 457

-1

137977

PRK10549

signal transduction histidine-protein kinase BaeS; Provisional

false

true

false

467

1e-26

115.59

46.25

3,131,242,35,168,277,104,276,381,77

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 132 DFIANVSHELKTPVGAMLLLAEAIRDAQDDPAALThfIDRLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIVS 211
PRK10549     243 DFMADISHELRTPLAVLRGELEAIQDGVRKFTPES--VASLQAEVGTLTKLVDDLHQLSLSDEGALAYQKTPVDLVPLLE 320

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 212 DAVEPLHVRAEAAGIRLEVAIPANLCVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARErvtpEGRIVEIAVSDNGIG 291
PRK10549     321 VAGGAFRERFASRGLTLQFSLPDSATVFGDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQ----HDKTLRLTFADSAPG 396

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 117927300 292 IARADQERIFERFYRVDPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
PRK10549     397 VSDEQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELP 458

-1

132001

TIGR02956

TMAO_torS

TMAO reductase sytem sensor TorS

false

true

false

968

3e-26

114.88

22.52

6,132,466,28,161,494,75,236,571,40,280,611,28,309,639,5,315,644,40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 133 FIANVSHELKTPVGAMLLLAEAIRDAQDdPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIVSD 212
TIGR02956    467 FLATMSHEIRTPLNGILGTLELLGDTGL-TSQQQQYLQVINRSGESLLDILNDILDYSKIEAGHLSISPRPFDLNALLDD 545

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 213 AVEPLHVRAEAAGIRLEVAIPANL--CVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARERVTPegriVEIAVSDNGI 290
TIGR02956    546 VHHLMVSRAQLKGIQLRLNIPEQLpnWWQGDGPRIRQVLINLVGNAIKFTDRGSVVLRVSLNDDSS----LLFEVEDTGC 621

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 117927300 291 GIARADQERIFERFYRVDpGRSRAtGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLPAP 355
TIGR02956    622 GIAEEEQATLFDAFTQAD-GRRRS-GGTGLGLAISQRLVEAMDGELGVESELGVGSCFWFTLPLT 684

-1

137828

PRK10337

sensor protein QseC; Provisional

false

true

false

446

2e-23

105.63

45.52

6,132,236,107,239,344,21,275,365,9,284,381,22,307,403,7,316,410,29

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 133 FIANVSHELKTPVGAMLLLAEAIRDAQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIVSD 212
PRK10337     237 FTSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKALLQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQS 316

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 213 AVEPLHVRAEAAGIRLEVAIPANLCVL-GDRRQLATAVTNLVENAIVYSsrggrvgvgarervtPEGRIVEIA------- 284
PRK10337     317 AVMDIYHTAQQAKIDVRLTLNAHGIKRtGQPLLLSLLVRNLLDNAVRYS---------------PQGSVVDVTlnarnft 381

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117927300 285 VSDNGIGIARADQERIFERFYRvDPGRSRAtgGTGLGLAIVKHIVNNHGGRISVWSKPGTG 345
PRK10337     382 VRDNGPGVTPEALARIGERFYR-PPGQTAT--GSGLGLSIVQRIAKLHGMNVSFGNAEEGG 439

-1

33974

COG4251

Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms]

Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal...

false

true

false

750

2e-23

105.03

28.53

9,132,526,13,145,543,18,165,561,27,194,588,37,231,626,3,237,629,24,275,653,8,283,672,24,309,696,44

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 133 FIANVSHELKTPV----GAMLLLAEAIRDAQDDPAalTHFIDRLIHEANRLSRLVKELIDLSRLqgGDPLPELSEVRVSD 208
COG4251      527 FAYVASHDLQEPLrqisNYAQLLSERYSDALDEEA--KEFITFISRLTSLMQQLIDDLLTYSKL--GLTEAPLQPTDVQK 602

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 209 IVSDAVEPLHVRAEAAGIRLEVA-IPAnlcVLGDRRQLATAVTNLVENAIVYSSrggrvgvgarervtPEGRIVEI---- 283
COG4251      603 VVDKVLLELSQRIADTGAEIRIApLPV---VAADATQLGQVFQNLIANAIKFGG--------------PENPDIEIsaer 665

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117927300 284 -------AVSDNGIGIARADQERIFERFYRVdpGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
COG4251      666 qedewtfSVRDNGIGIDPAYFERIFVIFQRL--HSRDEYLGTGLGLAICKKIAERHQGRIWVESTPGEGSTFYFTLP 740

-1

138409

PRK11107

hybrid sensory histidine kinase BarA; Provisional

false

true

false

920

2e-23

104.98

24.24

6,131,294,13,144,311,2,146,314,15,164,329,7,174,336,62,236,400,117

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 132 DFIANVSHELKTP----VG-AMLLLAEAIRDAQDDpaaLTHFIDRlihEANRLSRLVKELIDLSRLQGGDPLPELSEVRV 206
PRK11107     295 EFLANMSHELRTPlngvIGfTRQTLKTPLTPTQRD---YLQTIER---SANNLLAIINDILDFSKLEAGKLILENIPFSL 368

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 207 SDIVSDAVEPLHVRAEAAGIRLEVAIPANL--CVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARERVTPEGRIVEIA 284
PRK11107     369 RETLDEVVTLLAHSAHEKGLELTLNIDPDVpdNVIGDPLRLQQIITNLVGNAIKFTESGNIDILVELRALSDEKVQLEVQ 448

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117927300 285 VSDNGIGIARADQERIFERFYRVDPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
PRK11107     449 IRDTGIGISERQQSQLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHLP 517

-1

138397

PRK11091

aerobic respiration control sensor protein ArcB; Provisional

false

true

false

779

2e-22

101.61

28.63

11,131,284,37,170,321,4,174,326,21,195,351,4,203,355,29,232,388,10,242,399,3,248,402,24,276,426,32,308,460,8,317,468,39

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 132 DFIANVSHELKTPVGAMLLLAEAIRDAQDDPAALTHFidRLIH-EANRLSRLVKELIDLSRLQGG----DPLPelseVRV 206
PRK11091     285 TFISTISHELRTPLNGIVGLSRMLLDTELTAEQEKYL--KTIHvSAITLGNIFNDIIDMDKMDRRklqlDNQP----VDF 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 207 SDIVSDAVEPLHVRAEAAGIRLEVAI----PANLCVLGDR-RQLataVTNLVENAIVYSSRGGRVGVGARErvtpEGRIV 281
PRK11091     359 TDFLADLENLSGLQAEQKGLRFDLEPllplPHKVITDGTRlRQI---LWNLISNAVKFTQQGQVTVRVRYE----DGDML 431

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117927300 282 EIAVSDNGIGIARADQERIFERFYRVD--PGRSRATGgTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLPAPA 356
PRK11091     432 HFEVEDSGIGIPEDELDKIFAMYYQVKdsHGGKPATG-TGIGLAVSRRLAQNMGGDITVTSEEGKGSTFTLTIHAPA 507

-1

139897

PRK13837

two-component VirA-like sensor kinase; Provisional

false

true

false

831

8e-22

99.76

26.23

7,136,459,63,203,522,16,220,538,15,235,554,21,256,586,51,310,637,3,316,640,37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 137 VSHELKTPVGAMLLLAEAIRDAQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGGDPLPelseVRVSDIVSDAVEP 216
PRK13837     460 IAHNFNNILGAILGYAEMALNKLRRHSRARRHIDEIISSGDRARLIIDQILTFGRKGERRTKP----FSLSELVTEIAPL 535

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 217 LHVrAEAAGIRLEVAIPAN-LCVLGDRRQLATAVTNLVENA-----------IVYSSRGGRVGVGARERVTPEGRIVEIA 284
PRK13837     536 LRV-SLPPTVELDFDFDQEpAVVEGNPAQLQQVILNLCKNAaqamdengrvdIRLSRVDLRKPKVLAHGTAPPGRYVLLR 614

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117927300 285 VSDNGIGIARADQERIFERFYRVdpgRSRatgGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
PRK13837     615 VSDTGRGIDEAVLPHIFEPFFTT---RAR---GTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDVYLP 677

-1

138539

PRK11360

sensory histidine kinase AtoS; Provisional

false

true

false

607

2e-21

98.61

34.10

6,133,391,24,158,415,36,198,451,38,236,490,41,280,531,30,316,561,37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 134 IANVSHELKTPVGAMLLLAEAIRDaQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGgdplPELSEVRVSDIVSDA 213
PRK11360     392 MAGVAHEIRNPLTAIRGYVQILRQ-QTSDPIHQEYLSVVLREVDSLNKVIQQLLEFSRPRH----SQWQQVSLNALVEEV 466

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 214 VEPLHVRAEAAGIRLEVAIPANL-CVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARERVTPEgriVEIAVSDNGIGI 292
PRK11360     467 LVLVQTAGVQARVDFITELDNELpPINADRELLKQVLLNILINAVQAISARGKIRIRTWQYSDSQ---QAISIEDNGCGI 543

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117927300 293 ARADQERIFERFYRVDPGrsratgGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
PRK11360     544 DLELLKKIFDPFFTTKAS------GTGLGLALSQRIINAHQGDIRVASLPGYGTTFTLILP 598

-1

137545

PRK09835

sensor kinase CusS; Provisional

false

true

false

482

3e-21

97.60

44.81

6,131,263,98,229,362,6,237,368,22,274,390,4,278,405,63,342,468,11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 132 DFIANVSHELKTPVGAMLLLAEAIRDAQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIVS 211
PRK09835     264 NFSADIAHEIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKKMLNLADEVG 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 212 DAVEPLHVRAEAAGIRLE-VAIPANlcVLGDRRQLATAVTNLVENAIVYssrggrvgvgarervTPEG-----------R 279
PRK09835     344 KVFDFFEALAEDRGVELRfVGDPCQ--VAGDPLMLRRALSNLLSNALRY---------------TPEGeaivvrcqtvdH 406

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117927300 280 IVEIAVSDNGIGIARADQERIFERFYRVDPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKpGTGSTFTLHLP 353
PRK09835     407 QVQVVVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSD-ARGTRFVISLP 479

-1

138021

PRK10604

sensor protein RstB; Provisional

false

true

false

433

7e-21

96.68

47.81

6,133,215,12,146,227,20,171,247,44,217,291,18,235,310,35,276,345,77

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 134 IANVSHELKTPVgAMLLLAEAIRDAQDDPAALThfidrLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIVSDA 213
PRK10604     216 IDGIAHELRTPL-VRLRYRLEMSDNLSAAESQA-----LNRDIGQLEALIEELLTYARLDRPQNELHLSEPDLPAWLSTH 289

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 214 VEplHVRAEAAGIRLEVAIPAN-LCVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGArervtpEGRIVEIAVSDNGIGI 292
PRK10604     290 LA--DIQAVTPEKTVRLKTPHQgDYGALDMRLMERVLDNLLNNALRYSHSTVETSLLL------DGDQATLIVEDDGPGI 361

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117927300 293 ARADQERIFERFYRVDPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
PRK10604     362 APEERERIFEPFVRLDPSRDRATGGCGLGLAIVHSIALAMGGSVNCDTSELGGARFSFSWP 422

-1

137612

PRK09959

hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional

false

true

false

1197

9e-19

89.79

18.46

3,132,714,99,231,815,83,316,898,37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300  133 FIANVSHELKTPVGAMLLLAEAIRDAQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIVSD 212
PRK09959      715 FLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQN 794

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300  213 AVEPLHVRAEAAGIRLEVA--IPANLCVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARERVTPEGRIVEIAVSDNGI 290
PRK09959      795 TCHSFGAIAASKSIALSCSstFPEHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLGHIDDNHAVIKMTIMDSGS 874

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 117927300  291 GIARADQERIFERFYRVDPGRSRAtgGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
PRK09959      875 GLSQEEQQQLFKRYSQTSAGRQQT--GSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIP 935

-1

138212

PRK10841

hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional

false

true

false

947

6e-17

83.55

22.91

10,132,472,12,144,488,7,160,495,27,187,526,8,195,538,2,198,540,23,226,563,2,228,571,9,239,580,32,276,612,77

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 133 FIANVSHELKTP----VGAMLLLaeairdaqdDPAALTHFIDRLIHEANRLSRLVKELI----DLSRLQGG----DPlPE 200
PRK10841     473 FLATVSHELRTPlygiIGNLDLL---------QTKELPKGVDRLVTAMNNSSSLLLKIIsdilDFSKIESEqlkiEP-RE 542

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 201 LSEVRVSDIVSDAVEPLHVRAeaagiRL------EVAIPANLCvlGDRRQLATAVTNLVENAIVYSSRGGRVGVGARerv 274
PRK10841     543 FSPREVMNHITANYLPLVVKK-----QLglycfiEPDVPVSLN--GDPMRLQQVISNLLSNAIKFTDTGCIILHVRV--- 612

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117927300 275 tpEGRIVEIAVSDNGIGIARADQERIFERFYRVDPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
PRK10841     613 --DGDYLSFRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTVRIP 689

-1

33642

COG3852

NtrB

Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]

true

false

363

1e-16

82.65

97.52

13,16,0,19,38,19,20,58,53,26,87,79,29,116,118,29,145,151,15,162,166,7,172,173,32,209,205,28,237,234,43,280,287,21,307,308,36,344,344,10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300  17 PAVADDGESREILDTVLRSleaAAIVTEGDRVVVSNEAAAAL--------------RLVFDGRLTSGVLAQLAAESQRVG 82
COG3852        1 MAMPTEPLAGAILNNLINP---VLLVDDELAIHYANPAAEQLlavsarrlagtrlsELLPFGSLLLSLLDQVLERGQPVT 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300  83 RRvvaEIELPWGETVRAVHAVAAPVLDSKRVVLL----------VTDVEESRRVEAVRRDFIANVSHELKTPV----GAM 148
COG3852       78 EY---EVTLVILGRSHIVDLTVAPVPEEPGSVLLefhprdmqrrLDREQTQHAQQRAVKGLVRGLAHEIKNPLggirGAA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 149 LLLAEAIRDAQDdpAALTHFIdrlIHEANRLSRLVKELIDLSRLQGGDPLPELSEVrvsdiVSDAVEPLHVRAEAAGIRL 228
COG3852      155 QLLERALPDEAL--RELTQLI---IEEADRLRNLVDRLEVLGPQRPGDRVPVNIHE-----VLERVRALVEAEFADNVRL 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 229 EVAIPANLC-VLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARERVTPEGRI----------VEIAVSDNGIGIARADQ 297
COG3852      225 IRDYDPSLPeVLGDRDQLIQVFLNLVRNAAQALGGRADEGGEIILRTRTGIQLtiagtryrlaLPLEVIDNGPGVPPDLQ 304

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 117927300 298 ERIFerfyrvDPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGtGSTFTLHLPA 354
COG3852      305 DHLF------YPMVSGREGGTGLGLALAQNLIDQHGGKIEFDSWPG-RTVFRVLLPI 354

-1

137309

PRK09467

envZ

osmolarity sensor protein; Provisional

false

true

false

437

1e-16

82.27

43.25

10,133,234,17,150,262,5,155,268,20,179,288,13,205,301,6,212,307,23,237,330,6,247,336,23,276,359,36,314,395,28

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 134 IANVSHELKTPVGAMLL-----------LAEAI-RDAQDDPAALTHFIDRLIHEanrlSRLVKELIDLSRLqggdplpel 201
PRK09467     235 MAGVSHDLRTPLTRIRLatemmseedgyLAESInKDIEECNAIIEQFIDYLRTD----QEMPMEMADLNAL--------- 301

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 202 sevrVSDIVSdAVEPLHVRAEAAGIRLEVAIPANlcVLGDRRqlatAVTNLVENAIVYSSRGGRVGVGArervtpEGRIV 281
PRK09467     302 ----LGEVIA-AESGYEREIETALYPGPIEVPMN--PIAIKR----ALANLVVNAARYGNGWIKVSSGT------EGNRA 364

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117927300 282 EIAVSDNGIGIARADQERIFERFYRVDPGRSraTGGTGLGLAIVKHIVNNHGGRISVWSKP 342
PRK09467     365 WFQVEDNGPGIPEEQIKHLFQPFTRGDSARG--SSGTGLGLAIVKRIVDQHQGKVELGNRE 423

-1

33926

COG4191

Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms]

Signal transduction histidine kinase regulating C4-dicarboxylate transport system [...

false

true

false

603

2e-16

81.86

35.32

7,134,388,21,155,414,19,177,433,22,203,455,30,233,486,24,259,510,53,316,563,38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 135 ANVSHELKTPVGAMLLLAEAI-----RDAQDDPAALTHFIDRLIHeanRLSRLVKELIDLSRLQGGDPLPelseVRVSDI 209
COG4191      389 AGIAHELNQPLAAIRTYADNArllleRGRTEEARENLERISALTE---RMAAITAHLKSFARKSRDAAGP----VSLREA 461

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 210 VSDAVEPLHVRAEAAGIRLEVAIP-ANLCVLGDRRQLATAVTNLVENAIvySSRGGRVGVGARERVTPEGRIVEIAVSDN 288
COG4191      462 IEGALELLRGRLRAAGVELELDLPdAPLWVMANEIRLEQVLVNLLQNAL--DAMAGQEDRRLSIRAQREGGQVVLTVRDN 539

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117927300 289 GIGIARADQERIFERFYRVDPGRSratgGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLPA 354
COG4191      540 GPGIAPEALPHLFEPFFTTKPVGK----GLGLGLAISQNIARDLGGSLEVANHPEGGASFTIELRR 601

-1

34605

COG5000

NtrY

Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms]

Signal transduction histidine kinase involved in nitrogen fixation and metabolism...

false

true

false

712

3e-16

81.15

48.88

10,7,350,42,49,394,25,74,428,57,131,487,25,156,517,36,196,553,36,233,589,44,277,637,4,282,641,20,308,661,37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300   8 VRNSRYATRPAVADDGESREILDTVLRSLEAAAIVTEGDRVV--VSNEAAAALRLVFDGRLTSGVLAQL---------AA 76
COG5000      351 LSSQQEALERAKDALEQRRRFLEAVLSGLTAGVIGFDNRGCIttVNPSAEQILGKPFDQLLGQSLSAIApeleevfaeAG 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300  77 ESQRVGRRVVAEIELPWGETVRAVHAVAAPVLDSKRVVLLVTDVEESRRVEAVRR--DFIANVSHELKTPVGAMLLLAEA 154
COG5000      431 AAARTDKRVEVKLAREGEERTLNVQATREPEDNGNGYVVTFDDITDLVIAQRSAAwgDVARRIAHEIKNPLTPIQLSAER 510

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 155 IR-----DAQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLqggdPLPELSEVRVSDIVSDAVEPLHVRAEAAGIRLE 229
COG5000      511 LLrklgkEIDEDREVFDRCTDTIIRQVEDIKRMVDEFRAFARM----PAPKLEKSDLRALLKEVSFLYEIGNDHIVFAAE 586

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 230 VAIpANLCVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARERVTPE----GRIVeIAVSDNGIGIARADQERIFErfy 305
COG5000      587 FGG-EPLIGMADATLLGQVFGNLLKNAAEAIEAVEAEERRTALIRVSLddadGRIV-VDVIDNGKGFPRENRHRALE--- 661

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 117927300 306 rvdPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTG 345
COG5000      662 ---PYVTTREKGTGLGLAIVKKIVEEHGGRLELHNAPDFD 698

-1

137849

PRK10364

sensor protein ZraS; Provisional

false

true

false

455

6e-16

80.36

45.93

8,134,242,23,158,265,15,173,281,18,198,299,1,199,303,30,229,334,28,261,362,44,311,406,45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 135 ANVSHELKTPVGAMLLLAEAIRDaQDDPAALTHFIDRLI-HEANRLSRLVKELIDLSRlqggdplP---ELSEVRVSDIV 210
PRK10364     243 AGVAHEIRNPLSSIKGLAKYFAE-RAPAGGEAHQLAQVMaKEADRLNRVVSELLELVK-------PthlALQAVDLNTLI 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 211 SDAVEPLHVRAEAAGIRLE-VAIPANLCVLGDRRQLATAVTNLVENAIvyssRGGRVGVGARERVTPEGRIVEIAVSDNG 289
PRK10364     315 NHSLQLVSQDANSREIQLRfTANDTLPEIQADPDRLTQVLLNLYLNAI----QAIGQHGVISVTASESGAGVKISVTDSG 390

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 117927300 290 IGIARADQERIFERFYrvdpgrSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLPAPA 356
PRK10364     391 KGIAADQLEAIFTPYF------TTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLPVNI 451

-1

131962

TIGR02916

PEP_his_kin

putative PEP-CTERM system histidine kinase

false

true

false

679

6e-15

77.07

29.46

6,134,479,48,188,527,27,219,554,38,261,592,31,295,623,11,308,634,45

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 135 ANVSHELKTPVGAMLLLAEAIRDAQDDPAALTHFIDRLIHEANRLSRLvkelidLSRLQGGDPLPELSEVRVSDIVSDAV 214
TIGR02916    480 AFVVHDLKNLVAQLSLLLRNAERHKDNPEFQDDMLETVENAVNRMKKL------LAQLRSKGLEEEKLCVDLVDLLRRAI 553

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 215 EplhvRAEAAGIRLEVAIPANLCVLGDRRQLATAVTNLVENAIvyssRGGRVGVGARERVTPEGRIVEIAVSDNGIGIar 294
TIGR02916    554 A----SKRAQGPRPEVSIDTDLSVRADRERLERVLGHLVQNAL----EATPGEGRVAIRVERECGAARIEIEDSGCGM-- 623

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 117927300 295 aDQERIFERFYRvdPGRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
TIGR02916    624 -SPAFIRERLFK--PFDTTKGAGMGIGVYECRQYVEEIGGRIEVESTPGQGTIFTLVLP 679

-1

138589

PRK11466

hybrid sensory histidine kinase TorS; Provisional

false

true

false

912

1e-14

76.22

23.57

9,132,446,13,145,463,8,153,473,14,174,487,29,203,518,33,236,553,23,274,576,8,282,594,29,315,623,38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 133 FIANVSHELKTPV----GAMLLLAE--AIRDAQDDPAALTHfidrlihEANRLSRLVKELIDLSRLQGGDPLPELSE--V 204
PRK11466     447 FLAAMSHEIRTPLygilGTAQLLADnpALNAQRDDLRAITD-------SGESLLTILNDILDYSAIEAGGKNVSVSDepF 519

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 205 RVSDIVSDAVEPLHVRAEAAGIRLEVAIPANL--CVLGDRRQLATAVTNLVENAIVYssrggrvgvgarervTPEGRIVE 282
PRK11466     520 EPRPLLESTLQLMSGRVKGRPIRLATDIADDVpsALMGDPRRIRQVITNLLSNALRF---------------TDEGSIVL 584

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 283 ----------IAVSDNGIGIARADQERIFERFYRVDPGRsratGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHL 352
PRK11466     585 rsrtdgeqwlVEVEDSGCGIDPAKLAEIFQPFVQVSGKR----GGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRL 660


                 .
gi 117927300 353 P 353
PRK11466     661 P 661

-1

137934

PRK10490

sensor protein KdpD; Provisional

false

true

false

895

2e-14

75.55

23.91

6,133,667,23,156,691,73,231,764,9,240,774,30,274,804,34,310,838,43

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 134 IANVSHELKTPVGAMLLLAEAIR-DAQDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIVSD 212
PRK10490     668 LAALSHDLRTPLTVLFGQAEILTlDLASEGSPHARQASEIRQHVLNTTRLVNNLLDMARIQSGGFNLKKEWLTLEEVVGS 747

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 213 AVEPLHVRAEAAGIRLEvaIPANLCVLG-DRRQLATAVTNLVENAIVYSSRGGRVGVGArervTPEGRIVEIAVSDNGIG 291
PRK10490     748 ALQMLEPGLSQHPINLS--LPEPLTLIHvDGPLFERVLINLLENAVKYAGAQAEIGIDA----HVEGENLQLDVWDNGPG 821

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 117927300 292 IARADQERIFERFYRVDpgRSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
PRK10490     822 IPPGQEQLIFDKFARGN--KESAVPGVGLGLAICRAIVDVHGGTITAENRPEGGACFRVTLP 881

-1

138030

PRK10618

phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional

phosphotransfer intermediate protein in two-component regulatory system with RcsBC;...

false

true

false

881

4e-12

67.36

24.74

8,132,452,28,165,480,66,231,548,46,278,594,3,282,597,18,302,615,2,308,617,8,316,630,40

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 133 FIANVSHELKTPVGAMLLLAEAIRDAQDdpaalTHFIDRLIHEANRLSRLVKELIDLSRLQGGDPLPELSEVRVSDIVSD 212
PRK10618     453 FLQNIGDELKEPVQSLAELAAQLNAPES-----QQLLKQLAEQADVLVRLIDNIQLANMLENDEWKSEQTLFSLQDLIDE 527

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 213 AVEPLHVRAEAAGIRLEVA--IPANLCVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARERVTPEgRIVeIAVSDNGI 290
PRK10618     528 VVPEVLPAIKRKGLQLLIHnhLKANDMRRGDRDALRKILLLLLQYAVTTTQYGKITLEVDQDESSEE-RLT-FRILDTGE 605

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117927300 291 GIARADQERIfeRFyrvdPGRSRATG-----GTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLPAPA 356
PRK10618     606 GVSIHEIDNL--HF----PFLNQTQGdrygkASGLTFWLCNQLCRKLGGHLNIKSREDLGTRYSVHLKMLP 670

-1

138393

PRK11086

sensory histidine kinase DcuS; Provisional

false

true

false

541

6e-12

66.89

23.84

6,219,404,25,244,432,13,269,445,11,280,466,25,313,491,5,318,498,35

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 220 RAEAAGIRLEVAIPANLCVLGDRRQ---LATAVTNLVENAIvyssrggrvgvgARERVTPEGRI----------VEIAVS 286
PRK11086     405 RARELGITLIISEDSQLPDSDDEDQvheLITILGNLIENAL------------EAVSNEEGGEIsvslhyrhgwLHIEVS 472

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 117927300 287 DNGIGIARADQERIFERFYrvdpgrsrATGGT--GLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
PRK11086     473 DDGPGIAPEEIEAIFDKGY--------STKGSnrGVGLYLVKQSVENLGGSIAVESEPGIGTQFFVQIP 533

-1

33099

COG3290

CitA

Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]

Signal transduction histidine kinase regulating citrate/malate metabolism [Signal...

false

true

false

537

2e-11

65.63

24.39

4,219,399,25,244,427,14,259,441,47,311,488,42

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 220 RAEAAGIRLEVAIPANLCVLGDRRQ---LATAVTNLVENAIVySSRGGRVGVGARERVTPEGRIVEIAVSDNGIGIARAD 296
COG3290      400 RARELGVSLIIDPNSQLPQLPSELQphdLVTILGNLIDNALE-ALLAPEENKEIELSLSDRGDELVIEVADTGPGIPPEV 478

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 117927300 297 QERIFERFYRvdpgrSRATGGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
COG3290      479 RDKIFEKGVS-----TKNTGGRGIGLYLVKQLVERLGGSIEVESEKGQGTRFSIYIP 530

-1

138144

PRK10755

sensor protein BasS/PmrB; Provisional

false

true

false

355

2e-11

65.09

56.90

8,132,145,23,155,169,20,182,189,23,205,213,26,231,240,40,276,280,32,311,312,2,314,314,33

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 133 FIANVSHELKTPVGAMLLLAEAI-RDAQDDPAALTHFIDRLIHEanrlsrlVKELIDLSRLQGGDPLPELSEVR-VSDIV 210
PRK10755     146 FTADVAHELRTPLAGVRLHLELLaKTHHIDVAPLIARLDQMMHS-------VSQLLQLARAGQSFSSGNYQTVKlLEDVI 218

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 211 SDAVEPLHVRAEAAGIRLEVA-IPANLCVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARervtpEGRIVEIAVSDNG 289
PRK10755     219 LPSYDELSTMLEQRQQTLLLPeSAADITVQGDATLLRLLLRNLVENAHRYSPEGSNITIKLQ-----EDGGAVMAVEDEG 293

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 117927300 290 IGIARADQERIFERFYRVDpgrSRaTGGTGLGLAIVKHIVNNHGGRISVWSKPGTGST 347
PRK10755     294 PGIDESKCGELSKAFVRMD---SR-YGGIGLGLSIVSRITQLHHGQFFLQNRQERSGT 347

-1

138388

PRK11073

glnL

nitrogen regulation protein NR(II); Provisional

false

true

false

348

3e-10

61.27

61.78

12,131,131,32,164,163,19,189,182,5,198,187,9,214,196,27,241,234,15,256,252,22,278,277,3,281,281,20,304,301,8,315,309,29,345,338,8

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 132 DFIANVSHELKTPVGAMLLLAEAIRDAQDDPAaLTHFIDRLIHEANRLSRLVkelidlSRLQGgdplPELSEVRVSdivs 211
PRK11073     132 DLVRGLAHEIKNPLGGLRGAAQLLSKALPDPA-LTEYTKVIIEQADRLRNLV------DRLLG----PQRPGTHIT---- 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 212 davEPLHVRAEAAGIRLEVAIPANLCVLGD-----------RRQLATAVTNLVENA---IVYSSRGGRVGVGARERVTPE 277
PRK11073     197 ---ESIHKVAERVVQLVSLELPDNVRLIRDydpslpelahdPDQIEQVLLNIVRNAlqaLGPEGGEITLRTRTAFQLTLH 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 278 G---RIV-EIAVSDNGIGIARADQERIFerfYRVDPGRSratGGTGLGLAIVKHIVNNHGGRISVWSKPGTgSTFTLHLP 353
PRK11073     274 GeryRLAaRIDIEDNGPGIPPHLQDTLF---YPMVSGRE---GGTGLGLSIARNLIDQHSGKIEFTSWPGH-TEFSVYLP 346

-1

139663

PRK13557

histidine kinase; Provisional

false

true

false

538

3e-09

58.20

41.82

9,136,167,39,175,210,24,203,234,8,212,242,24,236,268,3,240,271,16,256,298,51,307,350,4,316,354,38

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 137 VSHELKTPVGAMLLLAEAIRDAQDDPAALTHFIDRLIHE----ANRLSRLVKELIDLSRLQGGDPLPelseVRVSDIVSd 212
PRK13557     168 IAHDFNNLLQVMSGYLDVLQMALSKPDADRERIARSVEHiraaAERAATLTQQLLAFARKQKLDGRV----VNLNGLVS- 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 213 AVEPLHVRAEAAGIRLEVAIPANL--CVLgDRRQLATAVTNLVENA-----------IVYSSRGGRVGVGARERVTPEGR 279
PRK13557     243 GMGEMAERTLGDAVTIETDLAPDLwnCRI-DPTQAEVALLNVLINArdampeggrvtVRTENVEITEHDLAMYHQLPPGR 321

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117927300 280 IVEIAVSDNGIGIARADQERIFERFYRV-DPGRsratgGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLPA 354
PRK13557     322 YVSIAVTDTGSGMPPEILARVMEPFFTTkEEGK-----GTGLGLSMVYGFAKQSGGAVRIYSEVGEGTTVRLYFPA 392

-1

33927

COG4192

Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]

Signal transduction histidine kinase regulating phosphoglycerate transport system [...

false

true

false

673

1e-08

56.24

29.42

6,133,454,25,158,481,39,199,520,34,234,554,38,274,592,30,310,622,30

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 134 IANVSHELKTPVGAMLLLAEAIRDA--QDDPAALTHFIDRLIHEANRLSRLVKELIDLSRLQGGDPlpELSEVRVSDIVS 211
COG4192      455 MTSLAHEINQPLNAMSAYLFSARLAleEAPSAQAATSLDKIENLTERMGKIVNSLRQFARKNSSDE--SLQPVRLNSVVE 532

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 212 DAVEPLHVRAEAAGIRLEVAIPaNLCVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARErvTPEGRIVEIAVSDNGIG 291
COG4192      533 QAWELLQTKHKRRQIKLINPTD-DLMVMGDAVSIEQVLVNLIVNALDASTHFAPWIKLIAL--GTEQEMLRIAIIDNGQG 609

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 117927300 292 IARADQERIFERFyrvdpgRSRATGGTGLGLAIVKHIVNNHGGRISVWS 340
COG4192      610 WPHELVDKLLTPF------TTSKEVGLGLGLSISQSLMEQMQGRLALAS 652

-1

131984

TIGR02938

nifL_nitrog

nitrogen fixation negative regulator NifL

false

true

false

494

2e-08

55.30

29.96

3,203,345,33,236,379,77,316,456,37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 204 VRVSDIVSDAVEPLHVRAEAAGIRLEVAIPANL-CVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARERVTPEGRIVE 282
TIGR02938    346 VNLNQILRDVITLSTPRLLAAGIVVDWQPAATLpAILGRELQLRSLFKALVDNAIEAMNIKGWKRRELSITTALNGDLIV 425

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117927300 283 IAVSDNGIGIARADQERIFERFYRVDPGRSRatgGTGLGLAIVKHIVNNHGGRISVWSKPGTGSTFTLHLP 353
TIGR02938    426 VSILDSGPGIPQDLRYKVFEPFFTTKGGSRK---HIGMGLSVAQEIVADHGGIIDLDDDYSEGCRIIVEFR 493

-1

32791

COG2972

Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]

Predicted signal transduction protein with a C-terminal ATPase domain [Signal...

false

true

false

456

2e-07

51.64

38.60

7,168,276,10,178,288,19,206,307,14,220,325,24,244,350,56,310,406,29,339,437,15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 169 IDRLIHEANR--LSRLVKELIDLSRLQGGDPlpelsevrvSDIVSDAVEPLHVR----AEAAGIRLEVAIPANLCVLGDR 242
COG2972      277 IRMLAEEDDPeeAAKVVKALSKLLRYSLSNL---------DNIVTLEIELLLIEkyleIQKLRIGDRLEVPLPIDEELEP 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 243 RQ-LATAVTNLVENAIVYSSRGGRVGVGARERVTPEGRIVEIAVSDNGIGIARADQERIferfyrvdpgRSRATGGTGLG 321
COG2972      348 LIdPKLVLQPLVENAIEHGIEPKRPGGSIAISAKKQDDVIQISISDNGPGIDEEKLEGL----------STKGENRSGIG 417

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 117927300 322 LAIVKHIVNNHGGRISVW--SKPGTGSTFTLHLPA 354
COG2972      418 LSNVKERLKLYFGEPGLSidSQPGKGTFVQIIIPK 452

-1

30988

COG0643

CheA

Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]

Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion /...

false

true

false

716

5e-05

44.16

13.97

5,276,472,16,295,488,8,303,520,1,307,521,9,316,535,37

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 277 EGRIVEIAVSDNGIGIaraDQERIFER------------------------FyrvDPGRSRATG-----GTGLGLAIVKH 327
COG0643      473 EGNNIVIEVSDDGAGI---DREKIREKaiergliteeeaetlsdeeilnliF---APGFSTAEQvtdvsGRGVGMDVVKT 546

                         90       100
                 ....*....|....*....|....*.
gi 117927300 328 IVNNHGGRISVWSKPGTGSTFTLHLP 353
COG0643      547 NIEQLGGSISVSSEPGKGTTFTIRLP 572

-1

138194

PRK10815

sensor protein PhoQ; Provisional

false

true

false

484

5e-04

40.85

21.49

3,224,357,50,280,407,32,316,439,22

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117927300 225 GIRLEVAIPANLCVLGDRRQLATAVTNLVENAIVYSSRGGRVGVGARERVtpegriVEIAVSDNGIGIARADQERIFERF 304
PRK10815     358 GVNISLDISPEISFVGEQNDFMEVMGNVLDNACKYCLEFVEISARQTDEH------LHIVVEDDGPGIPESKRELIFDRG 431

                         90       100       110
                 ....*....|....*....|....*....|....
gi 117927300 305 YRVDPGRSratgGTGLGLAIVKHIVNNHGGRISV 338
PRK10815     432 QRVDTLRP----GQGVGLAVAREITEQYEGKIVA 461

-1

ATP binding site	0	17	17	true	28956	cd00075	HATPase_c
Mg2+ binding site	1	1	1	true	28956	cd00075	HATPase_c
G-X-G motif	2	4	4	true	28956	cd00075	HATPase_c
phosphorylation site	0	1	1	true	119399	cd00082	HisKA
dimer interface	1	12	12	true	119399	cd00082	HisKA