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Conserved domains on  [gi|114016|sp|P02654|]
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RecName: Full=Apolipoprotein C-I; AltName: Full=Apolipoprotein C1; Contains: RecName: Full=Truncated apolipoprotein C-I; Flags: Precursor [Homo sapiens]

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List of domain hits

Name Accession Description Interval E-value
ApoC-I pfam04691
Apolipoprotein C-I (ApoC-1); Apolipoprotein C-I (ApoC-1) is a water-soluble protein component ...
27-83 2.70e-19

Apolipoprotein C-I (ApoC-1); Apolipoprotein C-I (ApoC-1) is a water-soluble protein component of plasma lipoprotein. It solubalises lipids and regulates lipid metabolizm. ApoC-1 transfers among HDL (high density lipoprotein), VLDL (very low-density lipoprotein) and chylomicrons. ApoC-1 activates lecithin:choline acetyltransferase (LCAT), inhibits cholesteryl ester transfer protein, can inhibit hepatic lipase and phospholipase 2 and can stimulate cell growth. ApoC-1 delays the clearance of beta-VLDL by inhibiting its uptake via the LDL receptor-related pathway. ApoC-1 has been implicated in hypertriglyceridemia, and Alzheimer's disease.


:

Pssm-ID: 147044  Cd Length: 61  Bit Score: 74.90  E-value: 2.70e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 114016     27 TPDVSSAL----DKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS 83
Cdd:pfam04691  1 EPDFSSKFeklpDKLKEFGNTLEDKAKTAIDRIKQSELMAKTRNWFSETFEKVKEKLKTTS 61
 
Name Accession Description Interval E-value
ApoC-I pfam04691
Apolipoprotein C-I (ApoC-1); Apolipoprotein C-I (ApoC-1) is a water-soluble protein component ...
27-83 2.70e-19

Apolipoprotein C-I (ApoC-1); Apolipoprotein C-I (ApoC-1) is a water-soluble protein component of plasma lipoprotein. It solubalises lipids and regulates lipid metabolizm. ApoC-1 transfers among HDL (high density lipoprotein), VLDL (very low-density lipoprotein) and chylomicrons. ApoC-1 activates lecithin:choline acetyltransferase (LCAT), inhibits cholesteryl ester transfer protein, can inhibit hepatic lipase and phospholipase 2 and can stimulate cell growth. ApoC-1 delays the clearance of beta-VLDL by inhibiting its uptake via the LDL receptor-related pathway. ApoC-1 has been implicated in hypertriglyceridemia, and Alzheimer's disease.


Pssm-ID: 147044  Cd Length: 61  Bit Score: 74.90  E-value: 2.70e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 114016     27 TPDVSSAL----DKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS 83
Cdd:pfam04691  1 EPDFSSKFeklpDKLKEFGNTLEDKAKTAIDRIKQSELMAKTRNWFSETFEKVKEKLKTTS 61
 
Name Accession Description Interval E-value
ApoC-I pfam04691
Apolipoprotein C-I (ApoC-1); Apolipoprotein C-I (ApoC-1) is a water-soluble protein component ...
27-83 2.70e-19

Apolipoprotein C-I (ApoC-1); Apolipoprotein C-I (ApoC-1) is a water-soluble protein component of plasma lipoprotein. It solubalises lipids and regulates lipid metabolizm. ApoC-1 transfers among HDL (high density lipoprotein), VLDL (very low-density lipoprotein) and chylomicrons. ApoC-1 activates lecithin:choline acetyltransferase (LCAT), inhibits cholesteryl ester transfer protein, can inhibit hepatic lipase and phospholipase 2 and can stimulate cell growth. ApoC-1 delays the clearance of beta-VLDL by inhibiting its uptake via the LDL receptor-related pathway. ApoC-1 has been implicated in hypertriglyceridemia, and Alzheimer's disease.


Pssm-ID: 147044  Cd Length: 61  Bit Score: 74.90  E-value: 2.70e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 114016     27 TPDVSSAL----DKLKEFGNTLEDKARELISRIKQSELSAKMREWFSETFQKVKEKLKIDS 83
Cdd:pfam04691  1 EPDFSSKFeklpDKLKEFGNTLEDKAKTAIDRIKQSELMAKTRNWFSETFEKVKEKLKTTS 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.11
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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