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Conserved domains on  [gi|487518213|ref|WP_001707965|]
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alpha,alpha-trehalase [Escherichia coli]

Protein Classification

alpha,alpha-trehalase( domain architecture ID 10014167)

alpha,alpha-trehalase catalyzes the hydrolysis of alpha,alpha-trehalose to form alpha- and beta-D-glucose

CATH:  1.50.10.10
CAZY:  GH37
EC:  3.2.1.28
Gene Ontology:  GO:0005993|GO:0004555
PubMed:  4377836|31925485
SCOP:  4001563

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
treA PRK13271
alpha,alpha-trehalase TreA;
1-565 0e+00

alpha,alpha-trehalase TreA;


:

Pssm-ID: 237326  Cd Length: 569  Bit Score: 1155.06  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213   1 MKSPAPSRP----QKMALIPACIFLCFAALSVQAEETPVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMIL 76
Cdd:PRK13271   1 MKSPAPRRPvllqQAMALAPAGILLCFAALSVQAEETSVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMIL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  77 ADYRMQQNQSGFDLLHFVNVNFPLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREV 156
Cdd:PRK13271  81 ADYRMQQNQSGFDLRHFVNVNFTLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 157 YYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQK 236
Cdd:PRK13271 161 YYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTWGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQK 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 237 EYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSR 316
Cdd:PRK13271 241 EYAYWMEGVENLQPGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSR 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 317 WMDNPHQLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDQQGWYADYDLKSHK 396
Cdd:PRK13271 321 WMDNPQQLNTIRTTSIVPVDLNALMFKMEKILARASKAAGDNAMANQYETLANARQKAIEKYLWNDKEGWYADYDLKSHK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 397 VRNQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSGKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDI 476
Cdd:PRK13271 401 VRNQLTAAALFPLYVNAAAKDRANKVAAATKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDV 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 477 SWHFLTNVQHTYDREKKLVEKYDVSTTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPTVKSATTQP 556
Cdd:PRK13271 481 TWRFLTNVQHTYDREKKLVEKYDVSSTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEKPCDNVPATRPASKSATPPP 560


                 ....*....
gi 487518213 557 STKEAQPTP 565
Cdd:PRK13271 561 KTKEATPTP 569
 
Name Accession Description Interval E-value
treA PRK13271
alpha,alpha-trehalase TreA;
1-565 0e+00

alpha,alpha-trehalase TreA;


Pssm-ID: 237326  Cd Length: 569  Bit Score: 1155.06  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213   1 MKSPAPSRP----QKMALIPACIFLCFAALSVQAEETPVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMIL 76
Cdd:PRK13271   1 MKSPAPRRPvllqQAMALAPAGILLCFAALSVQAEETSVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMIL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  77 ADYRMQQNQSGFDLLHFVNVNFPLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREV 156
Cdd:PRK13271  81 ADYRMQQNQSGFDLRHFVNVNFTLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 157 YYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQK 236
Cdd:PRK13271 161 YYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTWGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQK 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 237 EYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSR 316
Cdd:PRK13271 241 EYAYWMEGVENLQPGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSR 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 317 WMDNPHQLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDQQGWYADYDLKSHK 396
Cdd:PRK13271 321 WMDNPQQLNTIRTTSIVPVDLNALMFKMEKILARASKAAGDNAMANQYETLANARQKAIEKYLWNDKEGWYADYDLKSHK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 397 VRNQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSGKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDI 476
Cdd:PRK13271 401 VRNQLTAAALFPLYVNAAAKDRANKVAAATKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDV 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 477 SWHFLTNVQHTYDREKKLVEKYDVSTTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPTVKSATTQP 556
Cdd:PRK13271 481 TWRFLTNVQHTYDREKKLVEKYDVSSTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEKPCDNVPATRPASKSATPPP 560


                 ....*....
gi 487518213 557 STKEAQPTP 565
Cdd:PRK13271 561 KTKEATPTP 569
TreA COG1626
Neutral trehalase [Carbohydrate transport and metabolism];
100-535 0e+00

Neutral trehalase [Carbohydrate transport and metabolism];


Pssm-ID: 441233  Cd Length: 438  Bit Score: 785.19  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 100 LPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVAD 179
Cdd:COG1626    3 LPEPDESYVSDPGQTLREHIDALWPVLTRTPDEPNEGSSLLPLPHPYVVPGGRFREIYYWDSYFTMLGLAESGRWDLARD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 180 MVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVK 259
Cdd:COG1626   83 MVDNFAYLIDRYGHIPNGNRTYYLSRSQPPFFALMVELLAEHTGDEWLRRYLPQLEKEYAFWMDGADSLAPGQAYRRVVR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 260 LQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPHQLNTLRTTSIVPVDLNS 339
Cdd:COG1626  163 LPDGTVLNRYWDDRDTPRPESYREDVETAKQSPERPAEEVYRDLRAGAESGWDFSSRWLADGKDLATIRTTDIVPVDLNA 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 340 LMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDQQGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDRA 419
Cdd:COG1626  243 LLYHLETTLAKAYALAGDPAKAAEYRARAERRKEAINRYLWDEERGFYFDYDFVTGKQTAVLSAAAFYPLFAGIATPEQA 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 420 NKMATATKTHLLQPGGLNTTSGKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYD 499
Cdd:COG1626  323 ARVAETLEPQLLKPGGLVTTLVNSGQQWDAPNGWAPLQWMAVKGLRNYGYDDLAREIARRWLALVERVYERTGKLVEKYN 402

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 487518213 500 VSTTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPK 535
Cdd:COG1626  403 VVDPSLEAGGGEYPLQDGFGWTNGVYLALLALLGEP 438
Trehalase pfam01204
Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a ...
 55-532 0e+00

Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi.


Pssm-ID: 395961 [Multi-domain]  Cd Length: 509  Bit Score: 660.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213   55 KLFPDQKTFADAVPNSDPLMILADYRMQQNQ------SGFDLLHFVNVNFPLP--------KEGEKYVPP-----EGQSL 115
Cdd:pfam01204   1 KLFPDQKTFVDEARLNEPNRILRLIRAQFWRaltrriDGEDLRAFVEDYFDEPgdelprivPYDEKEQPEflqkiEDPDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  116 R---EHIDGLWPVLTR----STENTEKWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFAHEI 188
Cdd:pfam01204  81 RlwvEELNALWPALVRkinkKPGLLPEASSLLPLPNPFVVPGGRFRELYYWDSYFTILGLLESGMHDLAKGMVENFIYLI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  189 DTYGHIPNGNRSYYLSRSQPPFFALMVELLAQH-EGDAALKQYLPQMQKEYAYWMdgvenlqAGQQEKRVVKLQDGTLLN 267
Cdd:pfam01204 161 ETYGHIPNGNRSYYLNRSQPPFLTDMVLLVYEKtEDDALLRRYLAALKKEYAFWM-------ANPRLDPVTGLSDGYLLN 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  268 RYWDDRDTPRPESWVEDIATAKSNP-NRPATEIYRDLRSAAASGWDFSSRWMDNPH---QLNTLRTTSIVPVDLNSLMFK 343
Cdd:pfam01204 234 RYGVPPETPRPESYLEDVEYAEKLPkERPKAYNYRDLKAGAESGWDFSSRWVREGHdtgYLAEIRTTSLVPVDLNALLYK 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  344 MEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDQQGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDR----A 419
Cdd:pfam01204 314 YEKDIAFFCDVLGDSETSAIWEERAEQRRLAIDKYLWNEEAGVWFDYDLKKRKQTNYFSATNFWPLWAGLASPDQakmvA 393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  420 NKMATATKTHLLQ-PGGLNTTSGKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKY 498
Cdd:pfam01204 394 KVLPKLEESGLLVfPGGRPTSLLDSGQQWDYPNGWAPLQWLAVEGLQRYGYDELAERLAYRWLFTNTKAFVDEGKMVEKY 473

                         490       500       510
                  ....*....|....*....|....*....|....*
gi 487518213  499 DVSTTGTG-GGGGEYPLQDGFGWTNGVTLKMLDLI 532
Cdd:pfam01204 474 DVTRGGEYgGGGGEYVPQEGFGWTNGVYLYFLDLY 508
 
Name Accession Description Interval E-value
treA PRK13271
alpha,alpha-trehalase TreA;
1-565 0e+00

alpha,alpha-trehalase TreA;


Pssm-ID: 237326  Cd Length: 569  Bit Score: 1155.06  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213   1 MKSPAPSRP----QKMALIPACIFLCFAALSVQAEETPVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMIL 76
Cdd:PRK13271   1 MKSPAPRRPvllqQAMALAPAGILLCFAALSVQAEETSVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMIL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  77 ADYRMQQNQSGFDLLHFVNVNFPLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREV 156
Cdd:PRK13271  81 ADYRMQQNQSGFDLRHFVNVNFTLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 157 YYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQK 236
Cdd:PRK13271 161 YYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTWGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQK 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 237 EYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSR 316
Cdd:PRK13271 241 EYAYWMEGVENLQPGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSR 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 317 WMDNPHQLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDQQGWYADYDLKSHK 396
Cdd:PRK13271 321 WMDNPQQLNTIRTTSIVPVDLNALMFKMEKILARASKAAGDNAMANQYETLANARQKAIEKYLWNDKEGWYADYDLKSHK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 397 VRNQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSGKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDI 476
Cdd:PRK13271 401 VRNQLTAAALFPLYVNAAAKDRANKVAAATKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDV 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 477 SWHFLTNVQHTYDREKKLVEKYDVSTTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPTVKSATTQP 556
Cdd:PRK13271 481 TWRFLTNVQHTYDREKKLVEKYDVSSTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEKPCDNVPATRPASKSATPPP 560


                 ....*....
gi 487518213 557 STKEAQPTP 565
Cdd:PRK13271 561 KTKEATPTP 569
TreA COG1626
Neutral trehalase [Carbohydrate transport and metabolism];
100-535 0e+00

Neutral trehalase [Carbohydrate transport and metabolism];


Pssm-ID: 441233  Cd Length: 438  Bit Score: 785.19  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 100 LPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVAD 179
Cdd:COG1626    3 LPEPDESYVSDPGQTLREHIDALWPVLTRTPDEPNEGSSLLPLPHPYVVPGGRFREIYYWDSYFTMLGLAESGRWDLARD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 180 MVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVK 259
Cdd:COG1626   83 MVDNFAYLIDRYGHIPNGNRTYYLSRSQPPFFALMVELLAEHTGDEWLRRYLPQLEKEYAFWMDGADSLAPGQAYRRVVR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 260 LQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPHQLNTLRTTSIVPVDLNS 339
Cdd:COG1626  163 LPDGTVLNRYWDDRDTPRPESYREDVETAKQSPERPAEEVYRDLRAGAESGWDFSSRWLADGKDLATIRTTDIVPVDLNA 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 340 LMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDQQGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDRA 419
Cdd:COG1626  243 LLYHLETTLAKAYALAGDPAKAAEYRARAERRKEAINRYLWDEERGFYFDYDFVTGKQTAVLSAAAFYPLFAGIATPEQA 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 420 NKMATATKTHLLQPGGLNTTSGKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYD 499
Cdd:COG1626  323 ARVAETLEPQLLKPGGLVTTLVNSGQQWDAPNGWAPLQWMAVKGLRNYGYDDLAREIARRWLALVERVYERTGKLVEKYN 402

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 487518213 500 VSTTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPK 535
Cdd:COG1626  403 VVDPSLEAGGGEYPLQDGFGWTNGVYLALLALLGEP 438
treA PRK13272
alpha,alpha-trehalase TreA;
5-535 0e+00

alpha,alpha-trehalase TreA;


Pssm-ID: 183936  Cd Length: 542  Bit Score: 678.17  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213   5 APSRPQKMALIPACIFLCFAALSVQAEETPV------TPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMILAD 78
Cdd:PRK13272   4 APPCCTSLLGLSLSLLLAPCSLTAAPLDGPVvnapapTPPTPDLAYPELFQAVQEGELFDDQKHFVDALPLRDPALINAD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  79 YRMQQNQSGFDLLHFVNVNFPLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYY 158
Cdd:PRK13272  84 YLAQHEHPGFDLRKFVDANFEESPPVQTDAIRQDTALREHIDALWPKLVRSQEQVPAHSSLLALPHPYVVPGGRFREVYY 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 159 WDSYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQKEY 238
Cdd:PRK13272 164 WDSYFTMLGLVKSGQTTLSRQMLDNFAYLIDTYGHIPNGNRTYYLSRSQPPFFSYMVELQAGVEGDAAYQRYLPQLQKEY 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 239 AYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWM 318
Cdd:PRK13272 244 AYWMQGSDDLQPGQAARHVVRLADGSLLNRYWDERDTPRPEAWLHDTRTAAEAKDRPAAEVYRDLRAGAESGWDYSSRWL 323

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 319 DNPHQLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDqQGWYADYDLKSHKVR 398
Cdd:PRK13272 324 ADGKTLASIRTTAIVPVDLNSLLYHLERTLAQACASSGLAACSQDYAALAQQRKQAIDAHLWNP-AGYYADYDWQTRTLS 402

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 399 NQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSGKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISW 478
Cdd:PRK13272 403 EQVTAAALYPLFAGLASDDRAKRTADSVRAQLLRPGGLATTALKTGQQWDEPNGWAPLQWVAVDGLRRYGEDALARTIGE 482

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 487518213 479 HFLTNVQHTYDREKKLVEKYDVSTTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPK 535
Cdd:PRK13272 483 RFLAQVQALFAREHKLVEKYGLDGNAAGGGGGEYALQDGFGWTNGVTLMLLNLYPPG 539
Trehalase pfam01204
Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a ...
 55-532 0e+00

Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi.


Pssm-ID: 395961 [Multi-domain]  Cd Length: 509  Bit Score: 660.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213   55 KLFPDQKTFADAVPNSDPLMILADYRMQQNQ------SGFDLLHFVNVNFPLP--------KEGEKYVPP-----EGQSL 115
Cdd:pfam01204   1 KLFPDQKTFVDEARLNEPNRILRLIRAQFWRaltrriDGEDLRAFVEDYFDEPgdelprivPYDEKEQPEflqkiEDPDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  116 R---EHIDGLWPVLTR----STENTEKWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFAHEI 188
Cdd:pfam01204  81 RlwvEELNALWPALVRkinkKPGLLPEASSLLPLPNPFVVPGGRFRELYYWDSYFTILGLLESGMHDLAKGMVENFIYLI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  189 DTYGHIPNGNRSYYLSRSQPPFFALMVELLAQH-EGDAALKQYLPQMQKEYAYWMdgvenlqAGQQEKRVVKLQDGTLLN 267
Cdd:pfam01204 161 ETYGHIPNGNRSYYLNRSQPPFLTDMVLLVYEKtEDDALLRRYLAALKKEYAFWM-------ANPRLDPVTGLSDGYLLN 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  268 RYWDDRDTPRPESWVEDIATAKSNP-NRPATEIYRDLRSAAASGWDFSSRWMDNPH---QLNTLRTTSIVPVDLNSLMFK 343
Cdd:pfam01204 234 RYGVPPETPRPESYLEDVEYAEKLPkERPKAYNYRDLKAGAESGWDFSSRWVREGHdtgYLAEIRTTSLVPVDLNALLYK 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  344 MEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDQQGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDR----A 419
Cdd:pfam01204 314 YEKDIAFFCDVLGDSETSAIWEERAEQRRLAIDKYLWNEEAGVWFDYDLKKRKQTNYFSATNFWPLWAGLASPDQakmvA 393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  420 NKMATATKTHLLQ-PGGLNTTSGKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKY 498
Cdd:pfam01204 394 KVLPKLEESGLLVfPGGRPTSLLDSGQQWDYPNGWAPLQWLAVEGLQRYGYDELAERLAYRWLFTNTKAFVDEGKMVEKY 473

                         490       500       510
                  ....*....|....*....|....*....|....*
gi 487518213  499 DVSTTGTG-GGGGEYPLQDGFGWTNGVTLKMLDLI 532
Cdd:pfam01204 474 DVTRGGEYgGGGGEYVPQEGFGWTNGVYLYFLDLY 508
treF PRK13270
alpha,alpha-trehalase TreF;
47-531 0e+00

alpha,alpha-trehalase TreF;


Pssm-ID: 183934  Cd Length: 549  Bit Score: 611.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  47 LFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLLHFVNVNFPLPKEGE-KYVPPEGQSLREHIDGLWPV 125
Cdd:PRK13270  62 LFEHVQSSKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSsEYVSDPQNSLKEHIDQLWPV 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 126 LTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSR 205
Cdd:PRK13270 142 LTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSR 221

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 206 SQPPFFALMVELLaQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDI 285
Cdd:PRK13270 222 SQPPVFALMVELF-EEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDV 300

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 286 ATAKsNPNRPATEIYRDLRSAAASGWDFSSRWMDNPHQLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYE 365
Cdd:PRK13270 301 ETAK-HSGRPPNEVYRDLRAGAASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLYKLESAIANISALKGEKETEALFR 379

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 366 TLANARQKGIEKYMWNDQQGWYADYDLKshkvRNQL---TAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSGK 442
Cdd:PRK13270 380 QKASARRDAVNRYLWDDENGIYRDYDWR----REQLalfSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYE 455

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 443 SGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGG-GGEYPLQDGFGWT 521
Cdd:PRK13270 456 TGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYQEHHKLIEKYHIAGGVPREGgGGEYPLQDGFGWT 535

                        490
                 ....*....|
gi 487518213 522 NGVTLKMLDL 531
Cdd:PRK13270 536 NGVVRRLIGL 545
PLN02567 PLN02567
alpha,alpha-trehalase
 40-530 1.18e-132

alpha,alpha-trehalase


Pssm-ID: 215307  Cd Length: 554  Bit Score: 397.87  E-value: 1.18e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213  40 PDILLGPLFNDVQNAKL-------FPDQKTFAD---AVPNSDPLMILADY-RMQQNQSGF--DLLHFVNVNFPLP-KEGE 105
Cdd:PLN02567   3 PTTPLLTFLVRVQSTALasfggedTFDPKLYVDlplKFSLSETEKAFDALpRSNINGSVPveELEEFVAEYFDVAgSDLL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 106 KYVPP-------------EGQSLRE---HIDGLWPVLTR----STENTEKWDSLLPLPEPYVVPGGRFREVYYWDSYFTM 165
Cdd:PLN02567  83 PYTPPdfvpeppgflpkvENPEAREwalKVHSLWKNLARkvsdSVEERPDRHTLLPLPNPVVVPGSRFREVYYWDSYWVI 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 166 LGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAAL-KQYLPQMQKEYAYWMDG 244
Cdd:PLN02567 163 RGLLASKMYETAKGVVENLLYLVDTYGFVPNGARAYYTNRSQPPLLSAMVLAVYAATKDVELvRRALPALLKEHAFWTSG 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 245 venlqagqqeKRVVKLQDGT----LLNRYWDDRDTPRPESWVEDIATA-KSNPNRPATEIYRDLRSAAASGWDFSSRWMD 319
Cdd:PLN02567 243 ----------RHTVTIRDANgvvhVLSRYYAMWDKPRPESSRIDKEVAsKFSSSSEKQQLYRDIASAAESGWDFSSRWMR 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 320 NPHQLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDQQGWYADY--------D 391
Cdd:PLN02567 313 DGSNLTTLRTTSILPVDLNAFLLKMELDIAFFAKLLGDKATAERFLKAAKARKRAINAVLWNEEMGQWLDYwlppngatC 392

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 392 LKSHKVR----NQLTAAALF-PLYVNAAAKD--RANKMATATKTH-LLQPGGLNTTSGKSGQQWDAPNGWAPLQWVATEG 463
Cdd:PLN02567 393 QESYTWDaenqNTNVYASNFvPLWCGVVPPGdaKVEKVVESLKSSgLVLPAGIATSLRNTGQQWDFPNAWAPLQHMIVEG 472

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 487518213 464 LQNYG---QKEVAMDISWHFL-TNVQhTYDREKKLVEKYDVSTTGTGGGGGEYPLQDGFGWTNGVTLKMLD 530
Cdd:PLN02567 473 LAASGskeGKALAEDIARRWLrSNYV-AYKKTGAMHEKYDARYCGEVGGGGEYIPQTGFGWSNGVVLSLLE 542
GDB1 COG3408
Glycogen debranching enzyme (alpha-1,6-glucosidase) [Carbohydrate transport and metabolism];
141-481 3.24e-16

Glycogen debranching enzyme (alpha-1,6-glucosidase) [Carbohydrate transport and metabolism];


Pssm-ID: 442634 [Multi-domain]  Cd Length: 353  Bit Score: 80.31  E-value: 3.24e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 141 PLPEPYVVPG-GRFREVYYWDSYFTMLGLAeSGHWDKVADMVANFAHEIDTYGHIPN----GNRSYYLSRSQPPFFALMV 215
Cdd:COG3408   16 PGDGPTVIAGyPWFSTDWGRDTLIALPGLL-LLDPELARGILRTLARYQEEPGKIPHevrdGEEPYYGTVDATPWFIIAL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 216 ELLAQHEGDAA-LKQYLPQMQKEYAYWMDGVENlqagqqekrvvklQDGtLLnrywddrdtprpeswvediataksnpnr 294
Cdd:COG3408   95 GEYYRWTGDLAfLRELLPALEAALDWILRGDRD-------------GDG-LL---------------------------- 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 295 pateiyrdlrSAAASGWDfSSRWMDNPHQLNTLRttSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKG 374
Cdd:COG3408  133 ----------EYGRSGLD-NQTWMDSKVDSVTPR--SGALVEVQALWYNALRALAELARALGDPELAARWRELAERLKES 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 375 IEKYMWNDQQGWYADYDLKSHKVRNQLTAAALF--PLYVNAAAKDRANKMATATKT-HLLQPGGLNTTSGKSGqQWDAP- 450
Cdd:COG3408  200 FNERFWNEELGYLADALDGDGRPDDSIRPNQLFahALPTGILDPERARAVLRRLVSpELLTPWGLRTLSPGDP-AYNPMa 278

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 487518213 451 --NG--WAPLQWVATEGLQNYGQKEVAMDISWHFL 481
Cdd:COG3408  279 yhNGsvWPWLNGLYAEGLLRYGFREEARRLLEGLL 313
PRK10137 PRK10137
alpha-glucosidase; Provisional
 299-485 4.06e-03

alpha-glucosidase; Provisional


Pssm-ID: 236653  Cd Length: 786  Bit Score: 40.14  E-value: 4.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 299 IYRD-LRSAAASGW---DFSSRWMDNPHQLNTLRTTSIV--PVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQ 372
Cdd:PRK10137 536 IDKEqLDKYVANGGkrsDWTVKFAENRSQDGTLLGYSLLqeSVDQASYMYSDNHYLAEMATILGKPEEAKRYRQLAQQLA 615

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487518213 373 KGIEKYMWNDQQGWYADYDLKSHKVRNQLTAAALF----------PLYVNAAAKDRANKMATAtkthLLQPGGLNT---- 438
Cdd:PRK10137 616 DYINTCMFDETTGFYYDVRIEDKPLANGCAGKPIVergkgpegwsPLFNGAATQANADAVVKV----MLDPKEFNTfvpl 691

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 487518213 439 -TSGKSGQQWDAPNGWAPLQWV-----ATEGLQNYGQKEVAMDISWHFLTNVQ 485
Cdd:PRK10137 692 gTAALTNPAFGADIYWRGRVWVdqfyfGLKGMERYGYRDDALKLADTFFRHAK 744
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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