|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
113-1105 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 797.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 113 TVKGVVTDQNGDPIIGANVLEKGTTNGCITNMEGNFSLNVPSNSILTITYIGYHPQNIQVNGQQNLNIKMQEEAMALEQV 192
Cdd:TIGR04056 2 TVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDEV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 193 VVTAMGIKKKEaSLTYSTQQVGGDELTRAKDPNMINALAGKTAGVQITKSSSGLGGSAKVSIRGSRSISGNNQPLYVIDG 272
Cdd:TIGR04056 82 VVVGYGTQKKK-SLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVIDG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 273 VPMLNssneqastaiggtadagnrdggdGISNLNPDDIESMSILKGASAAALYGSQAANGVILITTKKGKAGIQKITFSS 352
Cdd:TIGR04056 161 VPRDN-----------------------GLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGKPKISYNA 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 353 NLTVDHAICLPEFQNSY-----------AMDPEAKNGWGKKATLKDYDNADN------------FFQNGVTAINSVSFMN 409
Cdd:TIGR04056 218 EFGFSTPTRLPEMLNAYeyaelyneallNRGSSPPDIYTDEEIEAYRNGLDPdlypntdwqdeiFKRTAFNQRHNLSVSG 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 410 GSEKMQTYFSYANTTAKGIVEKNKMQKHNLNFRETANfFNDYLKLDANVNLMTQTIKNRPTSggyYMNPLVGLYGFPRGE 489
Cdd:TIGR04056 298 GTEKARYYVSLGYYNEEGILKNSDYKRYNFRANIDAK-LTKTLKLSLNVSGSLSKYNNPGGS---TSNIWGALMLFPRGT 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 490 DLSEYKnnfeVFDPARNMNVQNWYTSYqdmeQNPYWITNRINSNDKRTRAIASLTANVKITDWLNIQARGTADYTHDQYQ 569
Cdd:TIGR04056 374 PYSTPP----VYSDGYYPAYNSGNTSL----QNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYDYSNYKNK 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 570 QR--MYASTAPALSGQNGRYIDLNHTETLYYGDVMAMINKKWNDFSLNGAIGGSINSTnvNSLRLDSKTASLyypnvftv 647
Cdd:TIGR04056 446 KYykNPYYYNATGGANNGYYSESNSRSRNYYLEATLNYNRTFGKHNVSALLGYSQQEN--KSSSYGGLLDDL-------- 515
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 648 ANIKMTQAAYIDEQINQKRVLQSLFGTAQLGWKESLYLDVTARNDWSSTLAyTKHSSFFYPSVGLSWVLNNTV---KLPE 724
Cdd:TIGR04056 516 PSLDAGTSDASVSGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFA-KGNRWGFFPSVSLGWRISEEKfmkKLKK 594
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 725 WISFGKIRGSWSKVGND--------LPLFISNTIPGSNDI-IGAGGAIVTYSKAPFNDLKPEMSTSYEIGTEWKFFNYRL 795
Cdd:TIGR04056 595 WLSFLKLRASYGIVGNDnigdrypyLSLYNLGDGGYNFGTnNGTSVTGITESRYGNPNLKWEKTKKWNLGLDLGFFNNRL 674
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 796 DFDFTYYRTNTKNQLF--TLPSSAGaeYKYYMVNAGNIQNEGIEITLGATPVMNDAFRWKIQFNFSTNKNKIIKLHPDLK 873
Cdd:TIGR04056 675 SLTVDYYYKKTKDILQsrSLPSVTG--YSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILELDEGAY 752
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 874 TFVygdesfssSYSMRLVEGGSFGDIYGK--------------AFERDKNGKVVFtADADGDkipNVIGGGNTEKVGNCN 939
Cdd:TIGR04056 753 LPV--------KYPYISKEGGPIGQIYGYiadglfkdddspkqTFGNVRPGDIKY-KDVNGD---GKIDDDDRVPIGYSN 820
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 940 -PDFMLGWSNTFTYKGFSLYFLIDGRFGGDVLSQTQAELDQRGVSLNSGKARDA-GYVNVDGTQVKPQKFYTAVSGRD-- 1015
Cdd:TIGR04056 821 tPDLTYGFGNSFSYKGFDLSALFQGSGGGDVFNDGRGFYPFNGGDWGNVLKIVAdNRWTPENPNADYPRLSYGDSNNSnn 900
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 1016 -GCTEYYMYDATNIRLRELSLGYSLPQSWLAKAGgaFKDVQLSFVARNLFFISKKAPFDPDAvlstgndnQGIDVFGMPT 1094
Cdd:TIGR04056 901 yQASTRWLEDGSYLRLKNLTLGYTLPKKWLKKIG--ISNLRVYFSGQNLFTFSKYKGWDPEL--------QGNDGGAYPL 970
|
1050
....*....|.
gi 1650039217 1095 TRSLGFNIKFT 1105
Cdd:TIGR04056 971 QRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
189-865 |
1.73e-44 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 171.93 E-value: 1.73e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 189 LEQVVVTAMGIKKKEASLTYSTQQVGGDELTRAKDPNMINALaGKTAGVQITKSSsglGGSAKVSIRGSRSisGNNQPLY 268
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSVTSAG---GGAGQISIRGFGG--GGNRVLV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 269 VIDGVPMLNSSNeqastaiggtadagnrdGGDGISNLNPDDIESMSILKGASAAaLYGSQAANGVILITTKKGKAGIQ-- 346
Cdd:COG1629 75 LVDGVPLNDPSG-----------------GDGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDGKGge 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 347 -KITFSSNLTVDHaiclpefqnsyamdpeakngwgkkatlkdydnadnffqngvtainSVSFMNGSEKMQTYFSYANTTA 425
Cdd:COG1629 137 vSASYGSYGTYRA---------------------------------------------SLSLSGGNGKLAYRLSASYRDS 171
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 426 KGIVEKNKMQKHNLNFReTANFFNDYLKLDANVNlmtqtiknrptsggyYMNPLVGLYGFPRGEDLSEYKNNFEVFDPAR 505
Cdd:COG1629 172 DGYRDNSDSDRYNLRAK-LGYQLGDDTRLTLSAS---------------YSDSDQDSPGYLTLAALRPRGAMDDGTNPYS 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 506 NmnvqnwytsyqdmeqnpywitnrinSNDKRTRAIASLTANVK-ITDWLNIQARGTADYTHDQYQQRMYASTApalsgQN 584
Cdd:COG1629 236 N-------------------------DTDDNTRDRYSLSLEYEhLGDGLKLSASAYYRYDDTDLDSDFTPTPA-----DG 285
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 585 GRYIDLNHTETLYYGDVMAMINKKWNDfSLNGAIGGSINSTNVNSLRLDSKTASLYYPNVFTVANIKMTQAAYideqinq 664
Cdd:COG1629 286 GTLEQTDFDNRTYGLELRLTYDLGFGG-KHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSGADDDGTTTSL------- 357
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 665 krvlqSLFGTAQLGWKESLYLDVTARNDWSSTLAY-----------TKHSSFFYPSVGLSWVLNNTVKLpewisfgkiRG 733
Cdd:COG1629 358 -----ALYAQDTYKLTDKLTLTAGLRYDYVSYDVDdtvtgtdsasgSRSYSAFSPSLGLTYQLSPNLSL---------YA 423
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 734 SWSKvgndlplfiSNTIPGSNDIIGAGGAIVTYskaPFNDLKPEMSTSYEIGTEWKFFNYRLDFDFTYYRTNTKNQLFTL 813
Cdd:COG1629 424 SYSR---------GFRAPTFGELYANGTDPYSV---GNPDLKPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILSV 491
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 1650039217 814 PSSAGAEYKYYMVNAGNIQNEGIEITLGATPVMNdafrWKIQFNFSTNKNKI 865
Cdd:COG1629 492 PLPNDSGFSTYYTNAGKARSYGVELELSYQLTPG----LSLNASYSYTDAKF 539
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
227-871 |
1.63e-20 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 97.14 E-value: 1.63e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 227 INALAGKTAGVQITksSSGLGGSAKVSIRGSRSisgnNQPLYVIDGVPMLNSSNeqastaiggtadagnrDGGDGISNLN 306
Cdd:cd01347 18 LADLLRRIPGVSVT--RGGGGGGSTISIRGFGP----DRTLVLVDGLPLASSNY----------------GRGVDLNTIP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 307 PDDIESMSILKGASAAaLYGSQAANGVILITTKKgkagiqkitfssnltvdhaiclpefqnsyamdpeAKNGWGKKATLk 386
Cdd:cd01347 76 PELIERVEVLKGPSSA-LYGSGAIGGVVNIITKR----------------------------------PTDEFGGSVTA- 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 387 DYdNADNFFQNGVTAINSVSFMNGSEKMQTYFSYANTTAKGIVEKNkmQKHNLNFRETANFfndYLKLDANVNLMTQTik 466
Cdd:cd01347 120 GY-GSDNSGSSGGGGFDVSGALADDGAFGARLYGAYRDGDGTIDGD--GQADDSDEERYNV---AGKLDWRPDDDTRL-- 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 467 nrptsggyymnplvglygfprgeDLSEYKNNFEVFDPARNMNVQ-NWYTSYQDMEQNPYWITNRINSNDKRTRAIASLTA 545
Cdd:cd01347 192 -----------------------TLDAGYQDQDADGPGGTLPANgTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLEH 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 546 NVKITDW-LNIQARGTADYTHDQYQQRMYASTAPALSGQNGRYIDlNHTETLYYGDvmAMINKKWNDFSLNGAIGGSINs 624
Cdd:cd01347 249 DLNDTGWtLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSS-ERDTTQLGFD--AGLNAPFGTGPVAHTLTLGVE- 324
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 625 tnvnslrldsktaslyypnvftvanikmtqaaYIDEQINQKrvLQSLFGTAQLGWKESLYLDVTARNDWSSTLAY----- 699
Cdd:cd01347 325 --------------------------------YRREELDEK--QTALYAQDTIELTDDLTLTLGLRYDHYDQDSKdtiag 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 700 ----TKHSSFFYPSVGLSWVLNNTVKLpewisfgkiRGSWSKVgndlplFisnTIPGSNDIIGAGGAIVTYSkAPFNDLK 775
Cdd:cd01347 371 gttaKKSYSHWSPSLGLVYKLTDGLSL---------YASYSQG------F---RAPSLGELYGGGSHGGTAA-VGNPNLK 431
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 776 PEMSTSYEIGTEWKFFNyRLDFDFTYYRTNTKNQLFTLPSSAGAEYKYYMVNAGNIQNEGIEITLGATPvmndAFRWKIQ 855
Cdd:cd01347 432 PEKSKQYELGLKYDPGD-GLTLSAALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARIRGVELEASYDL----TDGLGLT 506
|
650
....*....|....*.
gi 1650039217 856 FNFSTNKNKIIKLHPD 871
Cdd:cd01347 507 GSYTYTDTEVKRTDGA 522
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
114-194 |
2.66e-19 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 83.41 E-value: 2.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 114 VKGVVTD-QNGDPIIGANVLEKGTTNGCITNMEGNFSL-NVPSNS-ILTITYIGYHPQNIQV----NGQQNLNIKMQEEA 186
Cdd:pfam13715 1 ISGTVVDeNTGEPLPGATVYVKGTTKGTVTDADGNFELkNLPAGTyTLVVSFVGYKTQEKKVtvsnDNTLDVNFLLKEDA 80
|
....*...
gi 1650039217 187 MALEQVVV 194
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| STN |
pfam07660 |
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ... |
51-99 |
4.61e-08 |
|
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.
Pssm-ID: 429580 [Multi-domain] Cd Length: 51 Bit Score: 50.21 E-value: 4.61e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1650039217 51 FVYNKKNVDTRRTVNVQADNKAVSEVLDEAFKGTNIKYVMEGHNIVLTK 99
Cdd:pfam07660 2 ILYDSDLVDGKQSVSLNVGNVTLEEALDQLLAGTGLSYEIGGNTIVLRP 50
|
|
| PRK13486 |
PRK13486 |
TonB-dependent receptor; |
186-442 |
1.69e-05 |
|
TonB-dependent receptor;
Pssm-ID: 139606 [Multi-domain] Cd Length: 696 Bit Score: 48.86 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 186 AMALEQVVVTAMGIKKKEASLTYSTQQVGGDELTRAKDPNMINALAGkTAGVQItKSSSGLGGSAKVSIRGSRSisgnNQ 265
Cdd:PRK13486 22 AAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRS-VEGVDV-ESGTGKTGGLEISIRGMPA----SY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 266 PLYVIDGVPMlnssneqastaiGGTADAGNrdggDGISNLNPD------DIESMSILKGAsAAALYGSQAANGVILITTK 339
Cdd:PRK13486 96 TLILIDGVRQ------------GGSSDVTP----NGFSAMNTGfmpplaAIERIEVIRGP-MSTLYGSDAMGGVVNIITR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 340 KGKagiQKITFSSNLTVDhaiclpeFQNSyamdpeakNGWGKKATLkdydnadNFFQNGVTAINSVSF-MNGSEKMQ--- 415
Cdd:PRK13486 159 KNA---DKWLSSVNAGLN-------LQES--------NKWGNSSQF-------NFWSSGPLVDDSVSLqVRGSTQQRqgs 213
|
250 260
....*....|....*....|....*..
gi 1650039217 416 TYFSYANTTAKGIVEKNKMQKHNLNFR 442
Cdd:PRK13486 214 SVTSLSDTAATRIPYPTESQNYNLGAR 240
|
|
| STN |
smart00965 |
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ... |
49-97 |
5.96e-04 |
|
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.
Pssm-ID: 198033 [Multi-domain] Cd Length: 52 Bit Score: 38.64 E-value: 5.96e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1650039217 49 YLFVYNKKNVdTRRTVNVQADNKAVSEVLDEAFKGTNIKYVMEGHNIVL 97
Cdd:smart00965 1 LNFVYDPALV-AGRRVSLLLGNVTVEQALDRLLAGTGLTYRRIGGNTIV 48
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
113-1105 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 797.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 113 TVKGVVTDQNGDPIIGANVLEKGTTNGCITNMEGNFSLNVPSNSILTITYIGYHPQNIQVNGQQNLNIKMQEEAMALEQV 192
Cdd:TIGR04056 2 TVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDEV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 193 VVTAMGIKKKEaSLTYSTQQVGGDELTRAKDPNMINALAGKTAGVQITKSSSGLGGSAKVSIRGSRSISGNNQPLYVIDG 272
Cdd:TIGR04056 82 VVVGYGTQKKK-SLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVIDG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 273 VPMLNssneqastaiggtadagnrdggdGISNLNPDDIESMSILKGASAAALYGSQAANGVILITTKKGKAGIQKITFSS 352
Cdd:TIGR04056 161 VPRDN-----------------------GLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGKPKISYNA 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 353 NLTVDHAICLPEFQNSY-----------AMDPEAKNGWGKKATLKDYDNADN------------FFQNGVTAINSVSFMN 409
Cdd:TIGR04056 218 EFGFSTPTRLPEMLNAYeyaelyneallNRGSSPPDIYTDEEIEAYRNGLDPdlypntdwqdeiFKRTAFNQRHNLSVSG 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 410 GSEKMQTYFSYANTTAKGIVEKNKMQKHNLNFRETANfFNDYLKLDANVNLMTQTIKNRPTSggyYMNPLVGLYGFPRGE 489
Cdd:TIGR04056 298 GTEKARYYVSLGYYNEEGILKNSDYKRYNFRANIDAK-LTKTLKLSLNVSGSLSKYNNPGGS---TSNIWGALMLFPRGT 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 490 DLSEYKnnfeVFDPARNMNVQNWYTSYqdmeQNPYWITNRINSNDKRTRAIASLTANVKITDWLNIQARGTADYTHDQYQ 569
Cdd:TIGR04056 374 PYSTPP----VYSDGYYPAYNSGNTSL----QNPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYDYSNYKNK 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 570 QR--MYASTAPALSGQNGRYIDLNHTETLYYGDVMAMINKKWNDFSLNGAIGGSINSTnvNSLRLDSKTASLyypnvftv 647
Cdd:TIGR04056 446 KYykNPYYYNATGGANNGYYSESNSRSRNYYLEATLNYNRTFGKHNVSALLGYSQQEN--KSSSYGGLLDDL-------- 515
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 648 ANIKMTQAAYIDEQINQKRVLQSLFGTAQLGWKESLYLDVTARNDWSSTLAyTKHSSFFYPSVGLSWVLNNTV---KLPE 724
Cdd:TIGR04056 516 PSLDAGTSDASVSGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFA-KGNRWGFFPSVSLGWRISEEKfmkKLKK 594
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 725 WISFGKIRGSWSKVGND--------LPLFISNTIPGSNDI-IGAGGAIVTYSKAPFNDLKPEMSTSYEIGTEWKFFNYRL 795
Cdd:TIGR04056 595 WLSFLKLRASYGIVGNDnigdrypyLSLYNLGDGGYNFGTnNGTSVTGITESRYGNPNLKWEKTKKWNLGLDLGFFNNRL 674
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 796 DFDFTYYRTNTKNQLF--TLPSSAGaeYKYYMVNAGNIQNEGIEITLGATPVMNDAFRWKIQFNFSTNKNKIIKLHPDLK 873
Cdd:TIGR04056 675 SLTVDYYYKKTKDILQsrSLPSVTG--YSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILELDEGAY 752
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 874 TFVygdesfssSYSMRLVEGGSFGDIYGK--------------AFERDKNGKVVFtADADGDkipNVIGGGNTEKVGNCN 939
Cdd:TIGR04056 753 LPV--------KYPYISKEGGPIGQIYGYiadglfkdddspkqTFGNVRPGDIKY-KDVNGD---GKIDDDDRVPIGYSN 820
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 940 -PDFMLGWSNTFTYKGFSLYFLIDGRFGGDVLSQTQAELDQRGVSLNSGKARDA-GYVNVDGTQVKPQKFYTAVSGRD-- 1015
Cdd:TIGR04056 821 tPDLTYGFGNSFSYKGFDLSALFQGSGGGDVFNDGRGFYPFNGGDWGNVLKIVAdNRWTPENPNADYPRLSYGDSNNSnn 900
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 1016 -GCTEYYMYDATNIRLRELSLGYSLPQSWLAKAGgaFKDVQLSFVARNLFFISKKAPFDPDAvlstgndnQGIDVFGMPT 1094
Cdd:TIGR04056 901 yQASTRWLEDGSYLRLKNLTLGYTLPKKWLKKIG--ISNLRVYFSGQNLFTFSKYKGWDPEL--------QGNDGGAYPL 970
|
1050
....*....|.
gi 1650039217 1095 TRSLGFNIKFT 1105
Cdd:TIGR04056 971 QRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
189-865 |
1.73e-44 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 171.93 E-value: 1.73e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 189 LEQVVVTAMGIKKKEASLTYSTQQVGGDELTRAKDPNMINALaGKTAGVQITKSSsglGGSAKVSIRGSRSisGNNQPLY 268
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSVTSAG---GGAGQISIRGFGG--GGNRVLV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 269 VIDGVPMLNSSNeqastaiggtadagnrdGGDGISNLNPDDIESMSILKGASAAaLYGSQAANGVILITTKKGKAGIQ-- 346
Cdd:COG1629 75 LVDGVPLNDPSG-----------------GDGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDGKGge 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 347 -KITFSSNLTVDHaiclpefqnsyamdpeakngwgkkatlkdydnadnffqngvtainSVSFMNGSEKMQTYFSYANTTA 425
Cdd:COG1629 137 vSASYGSYGTYRA---------------------------------------------SLSLSGGNGKLAYRLSASYRDS 171
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 426 KGIVEKNKMQKHNLNFReTANFFNDYLKLDANVNlmtqtiknrptsggyYMNPLVGLYGFPRGEDLSEYKNNFEVFDPAR 505
Cdd:COG1629 172 DGYRDNSDSDRYNLRAK-LGYQLGDDTRLTLSAS---------------YSDSDQDSPGYLTLAALRPRGAMDDGTNPYS 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 506 NmnvqnwytsyqdmeqnpywitnrinSNDKRTRAIASLTANVK-ITDWLNIQARGTADYTHDQYQQRMYASTApalsgQN 584
Cdd:COG1629 236 N-------------------------DTDDNTRDRYSLSLEYEhLGDGLKLSASAYYRYDDTDLDSDFTPTPA-----DG 285
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 585 GRYIDLNHTETLYYGDVMAMINKKWNDfSLNGAIGGSINSTNVNSLRLDSKTASLYYPNVFTVANIKMTQAAYideqinq 664
Cdd:COG1629 286 GTLEQTDFDNRTYGLELRLTYDLGFGG-KHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSGADDDGTTTSL------- 357
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 665 krvlqSLFGTAQLGWKESLYLDVTARNDWSSTLAY-----------TKHSSFFYPSVGLSWVLNNTVKLpewisfgkiRG 733
Cdd:COG1629 358 -----ALYAQDTYKLTDKLTLTAGLRYDYVSYDVDdtvtgtdsasgSRSYSAFSPSLGLTYQLSPNLSL---------YA 423
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 734 SWSKvgndlplfiSNTIPGSNDIIGAGGAIVTYskaPFNDLKPEMSTSYEIGTEWKFFNYRLDFDFTYYRTNTKNQLFTL 813
Cdd:COG1629 424 SYSR---------GFRAPTFGELYANGTDPYSV---GNPDLKPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNEILSV 491
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 1650039217 814 PSSAGAEYKYYMVNAGNIQNEGIEITLGATPVMNdafrWKIQFNFSTNKNKI 865
Cdd:COG1629 492 PLPNDSGFSTYYTNAGKARSYGVELELSYQLTPG----LSLNASYSYTDAKF 539
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
182-864 |
4.15e-38 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 151.93 E-value: 4.15e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 182 MQEEAMALEQVVVTAMGIKKKEASLTYSTQQVGGDELTRAKDPNMINALAgKTAGVQITkSSSGLGGSAKVSIRGSrsis 261
Cdd:COG4771 20 LAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALR-LLPGVSVT-RSGGRGGSSGISIRGL---- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 262 GNNQPLYVIDGVPMLNSsneqastaiggtadagNRDGGDGISNLNPDDIESMSILKGAsAAALYGSQAANGVILITTKKG 341
Cdd:COG4771 94 GGDRVLVLIDGVPVNNP----------------ALGGGGDLSYIPPDDIERIEVIRGP-ASALYGSDAIGGVINIITKKP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 342 kagiqkitfssnltvdhaiclpefqnsyamdpeaKNGWGKKATLkDYDNADNFFQNGvtainSVSFMNGSEKMQTYFSYA 421
Cdd:COG4771 157 ----------------------------------TDELEGSVSL-GYGSNGNGTYSG-----SLSLGGPGDKLSFLLSGS 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 422 NTTAKGIVEKNKMQKHNLNFRETANF-------FNDYLKLDANVNLMTQTIKNRPTSGGyymnPLVGLYGFPRGEDLSEY 494
Cdd:COG4771 197 YRDRDGYLDYRNGGFVGNSGYERYNLnaklgyrLSDNHRLSLSGGYSRQDRDGGPPTLG----DTEISSDNAGDRDTTTD 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 495 KNNFEV---FDPARNMNVQnwyTSYQDMEQNPYWITNRINSNDKRTRAIASLTANVKITDWLNIQARGT--ADYTHDQYQ 569
Cdd:COG4771 273 RGNYSLrynGDLGDNLDLS---LYYSRTDRDSTNGSLGGSTGSFSDSDDTTYGLELDLTYPLGGNHTLTlgAEYRYDDLD 349
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 570 QRMYASTApalsgqngryidlnhtetlyygdvmaminkkwndfslngaiggsinstnvnslrldsktaslyypnvftvan 649
Cdd:COG4771 350 SSSFLGGA------------------------------------------------------------------------ 357
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 650 ikmtqaayideqiNQKRVLQSLFGTAQLGWKESLYLDVTARNDWSSTLAYTkHSSFFYPSVGLSWVLNNTVKLpewisfg 729
Cdd:COG4771 358 -------------DASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGAS-NYTAFSPRLGLRYDLSDNLTL------- 416
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 730 kiRGSWS---KVGNDLPLFISNTIPGSNDIIGAggaivtyskapfNDLKPEMSTSYEIGTEWKFFNYRLDFDFTYYRTNT 806
Cdd:COG4771 417 --RASYGrgfRAPSLAELYGSGTGTPGRYVLGN------------PDLKPETSDNYELGLEYRLGNGGLSLSLTGFYTDI 482
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 1650039217 807 KNQLFTLPSSAGAEYKYYMVNAGNIQNEGIEITLGATPvmNDAFRWKIQFNFSTNKNK 864
Cdd:COG4771 483 KDLIVLVPVGPGPGDVLQYENVGKARTYGLELELKYRL--GKGLTLTASYTYLDSKID 538
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
192-354 |
4.45e-34 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 132.30 E-value: 4.45e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 192 VVVTAMGIKKKEASLTYSTQQVGGDELTRAKDPNMINALAgKTAGVQItKSSSGLGGSAKVSIRGSRSisgnNQPLYVID 271
Cdd:COG4206 1 VVVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALR-RVPGVQV-SSSGGPGSAASISIRGLGS----NQTLVLID 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 272 GVPMLNSSNeqastaiggtadagnrdGGDGISNLNPDDIESMSILKGAsAAALYGSQAANGVILITTKKGKAGiQKITFS 351
Cdd:COG4206 75 GVPLNDPSL-----------------GGVDLSLIPPDDIERIEVLKGA-ASALYGSDAIGGVINITTKKGKKG-FKGSVS 135
|
...
gi 1650039217 352 SNL 354
Cdd:COG4206 136 ASY 138
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
227-871 |
1.63e-20 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 97.14 E-value: 1.63e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 227 INALAGKTAGVQITksSSGLGGSAKVSIRGSRSisgnNQPLYVIDGVPMLNSSNeqastaiggtadagnrDGGDGISNLN 306
Cdd:cd01347 18 LADLLRRIPGVSVT--RGGGGGGSTISIRGFGP----DRTLVLVDGLPLASSNY----------------GRGVDLNTIP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 307 PDDIESMSILKGASAAaLYGSQAANGVILITTKKgkagiqkitfssnltvdhaiclpefqnsyamdpeAKNGWGKKATLk 386
Cdd:cd01347 76 PELIERVEVLKGPSSA-LYGSGAIGGVVNIITKR----------------------------------PTDEFGGSVTA- 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 387 DYdNADNFFQNGVTAINSVSFMNGSEKMQTYFSYANTTAKGIVEKNkmQKHNLNFRETANFfndYLKLDANVNLMTQTik 466
Cdd:cd01347 120 GY-GSDNSGSSGGGGFDVSGALADDGAFGARLYGAYRDGDGTIDGD--GQADDSDEERYNV---AGKLDWRPDDDTRL-- 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 467 nrptsggyymnplvglygfprgeDLSEYKNNFEVFDPARNMNVQ-NWYTSYQDMEQNPYWITNRINSNDKRTRAIASLTA 545
Cdd:cd01347 192 -----------------------TLDAGYQDQDADGPGGTLPANgTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLEH 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 546 NVKITDW-LNIQARGTADYTHDQYQQRMYASTAPALSGQNGRYIDlNHTETLYYGDvmAMINKKWNDFSLNGAIGGSINs 624
Cdd:cd01347 249 DLNDTGWtLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSS-ERDTTQLGFD--AGLNAPFGTGPVAHTLTLGVE- 324
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 625 tnvnslrldsktaslyypnvftvanikmtqaaYIDEQINQKrvLQSLFGTAQLGWKESLYLDVTARNDWSSTLAY----- 699
Cdd:cd01347 325 --------------------------------YRREELDEK--QTALYAQDTIELTDDLTLTLGLRYDHYDQDSKdtiag 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 700 ----TKHSSFFYPSVGLSWVLNNTVKLpewisfgkiRGSWSKVgndlplFisnTIPGSNDIIGAGGAIVTYSkAPFNDLK 775
Cdd:cd01347 371 gttaKKSYSHWSPSLGLVYKLTDGLSL---------YASYSQG------F---RAPSLGELYGGGSHGGTAA-VGNPNLK 431
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 776 PEMSTSYEIGTEWKFFNyRLDFDFTYYRTNTKNQLFTLPSSAGAEYKYYMVNAGNIQNEGIEITLGATPvmndAFRWKIQ 855
Cdd:cd01347 432 PEKSKQYELGLKYDPGD-GLTLSAALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARIRGVELEASYDL----TDGLGLT 506
|
650
....*....|....*.
gi 1650039217 856 FNFSTNKNKIIKLHPD 871
Cdd:cd01347 507 GSYTYTDTEVKRTDGA 522
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
114-194 |
2.66e-19 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 83.41 E-value: 2.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 114 VKGVVTD-QNGDPIIGANVLEKGTTNGCITNMEGNFSL-NVPSNS-ILTITYIGYHPQNIQV----NGQQNLNIKMQEEA 186
Cdd:pfam13715 1 ISGTVVDeNTGEPLPGATVYVKGTTKGTVTDADGNFELkNLPAGTyTLVVSFVGYKTQEKKVtvsnDNTLDVNFLLKEDA 80
|
....*...
gi 1650039217 187 MALEQVVV 194
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
205-333 |
2.42e-18 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 81.55 E-value: 2.42e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 205 SLTYSTQQVGGDELTRAKDPNMINALAGkTAGVQItkSSSGLGGSAKVSIRGSrsisGNNQPLYVIDGVPMLNSSNeqas 284
Cdd:pfam07715 4 DTPGSVSVVTAEDIEDQGATNLADALRG-VPGVSV--SSGGGGGGSSISIRGF----GSNRVLVLVDGVPLNSGGG---- 72
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1650039217 285 taiggtadagnrdGGDGISNLNPDDIESMSILKGAsAAALYGSQAANGV 333
Cdd:pfam07715 73 -------------GSVDLNSIDPEDIERVEVLKGP-ASALYGSGAIGGV 107
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
483-844 |
5.17e-18 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 88.67 E-value: 5.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 483 YGFPRGEDLSEYKNNFEVFDPARNMNVQ-NWYTSYQDMEQNPYWITNRINSNDKRTRAIASLTANVKITDWLNIQARGTA 561
Cdd:pfam00593 6 LDLLGDDTLLTLGYDYSRYTDGLDLGLTlDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 562 DYTHDQYQQRMYASTapalsgqNGRYIDLNHTETLYYGDVMAMINKKWNDFSLNGAIGGSINSTNVNSLRLDSKTASLY- 640
Cdd:pfam00593 86 RYSSLDGDYTSNSSG-------LSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYd 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 641 --YPNVFTVANIKMTQAAyideqinqkrvlqsLFGTAQLGWKESLYLDVTARNDWSST---------LAYTKHSSFFYPS 709
Cdd:pfam00593 159 paNPSSSSYSDTTTDSYG--------------LYLQDNIKLTDRLTLTLGLRYDHYSTdgddgngggDNFSRSYSAFSPR 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 710 VGLSWVLNNTVKLpewisfgkiRGSWSKvgndlplfiSNTIPGSNDIIGAGGAIVTYSKAPFN-DLKPEMSTSYEIGteW 788
Cdd:pfam00593 225 LGLVYKPTDNLSL---------YASYSR---------GFRAPSLGELYGSGSGGGGGAVAGGNpDLKPETSDNYELG--L 284
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1650039217 789 KFFNYRLDFDFTYYRTNTKNQLFTLPSSAGAEYK-YYMVNAGNIQNEGIEITLGATP 844
Cdd:pfam00593 285 KYDDGRLSLSLALFYIDIKNLITSDPDGPGLGGTvYTYTNVGKARIRGVELELSGRL 341
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
183-859 |
1.83e-14 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 78.05 E-value: 1.83e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 183 QEEAMALEQVVVTAMGIKKKEA-SLTYSTQQVGGDELtRAKDPNMINALAGKTAGVQItKSSSGLGGSAKVSIRGS--RS 259
Cdd:COG4772 17 AEAATTLETVVVTGSRAAEARLkDVPGSVSVVDREEL-ENQAATSLREVLRRVPGVNV-QEEDGFGLRPNIGIRGLgpRR 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 260 ISGNNqpLYViDGVPMlnssneqastaiggTADAGnrdgGDGISNLNPDdIESMS---ILKGAsAAALYGSQAANGVILI 336
Cdd:COG4772 95 SRGIT--LLE-DGIPI--------------APAPY----GDPAAYYFPD-LERMErieVLRGA-AALRYGPQTVGGAINF 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 337 TTKKGKagiQKITFSSNLTVdhaiclpefqnsyamdpeakngwgkkatlkdydNADNFFQNGVtainSVSFMNGseKMQT 416
Cdd:COG4772 152 VTRTIP---TAFGGELRVTG---------------------------------GSFGYRRTHA----SVGGTVG--NFGY 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 417 YFSYANTTAKGIVEKNKMQKHNLNFRETANFfNDYLKLDANVNlmtqtiknrptsggyYMNPLVGLYGfprgeDLSEykn 496
Cdd:COG4772 190 LVEYSRKRGDGFRDNSGFDINDFNAKLGYRL-SDRQELTLKFQ---------------YYDEDANTPG-----GLTD--- 245
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 497 nfevfdparnmnvqnwytsyQDMEQNPYWiTNRINSNDKRTRAIASLTANVKITDWLNIQARGTADYTHDQYQQRMYAST 576
Cdd:COG4772 246 --------------------AQFDADPRQ-SYRPADQFDTRRTQLSLRYEHQLSDNTTLTTTAYYNDFSRNWYIRQNTAD 304
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 577 ApalsGQNGRYIDLNHTETLYYGdVMAMINKKWNDFSLNGAIGGSINSTN--------VNSLRLDSKTASLYYPNVFTVA 648
Cdd:COG4772 305 P----NTPGLGLRGNPRGYRSYG-IEPRLTHRFELGGVPHTLEVGLRYHReeedrkqyVNTYGQGRSGAGLRRDRRFSAD 379
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 649 NIkmtqAAYIDEQINqkrVLQSLFGTAQLGWkESLYLDVTARNDWSST--LAYTKHSSFFYPSVGLSWVLNNTVKLpewi 726
Cdd:COG4772 380 AL----AAYAQNRFE---LTGRLTLTPGLRY-EHIRRDRTDRYSTRTGgdDSGSNSYSEFLPGLGLLYQLTDNLQL---- 447
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 727 sFGKIRGSwskvgndlplFISntiPGSNDIIGAGGaivtyskaPFNDLKPEMSTSYEIGTEWKFFNyRLDFDFTYYRTNT 806
Cdd:COG4772 448 -YANVSRG----------FEP---PTFGDLAYGNG--------GNPDLKPEKSWNYELGTRGRIGN-GLSAEVALFYIDY 504
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|...
gi 1650039217 807 KNQLFTLPSSAGAEYKYymVNAGNIQNEGIEITLGATPVMNDAFRWKIQFNFS 859
Cdd:COG4772 505 DNELGSCSAAGGDRSTF--TNAGETRHQGLELALDYDLLKGGGLGLPLFAAYT 555
|
|
| SusC_RagA_signa |
TIGR04057 |
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ... |
309-339 |
5.62e-13 |
|
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.
Pssm-ID: 274949 [Multi-domain] Cd Length: 31 Bit Score: 63.75 E-value: 5.62e-13
10 20 30
....*....|....*....|....*....|.
gi 1650039217 309 DIESMSILKGASAAALYGSQAANGVILITTK 339
Cdd:TIGR04057 1 DIESISVLKDASAAAIYGSRGANGVILITTK 31
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
156-867 |
1.81e-12 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 71.46 E-value: 1.81e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 156 SILTITYIGYHPQNIQVNGQQNlnikMQEEAMALEQVVVTAmgikKKEASLTYSTQQVGGdeLTRAKDPNM--------- 226
Cdd:COG4773 3 ALLAGSGLAAAAAGALAQAAAA----AAAEATTLPEVTVTG----TAEGTGGYTAKSSST--ATKLDTPLRetpqsvsvv 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 227 ------------INALAGKTAGVQITKSSSGLGGSakVSIRGSRSISgnnqplYVIDGVPMLNSSNEQASTAIggtadag 294
Cdd:COG4773 73 trqliedqgattLDDALRNVPGVTVSSYDGGGRDS--FSIRGFSIDN------YLRDGLPLGGFGGGQPDTAN------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 295 nrdggdgisnlnpddIESMSILKGASAAaLYGSQAANGVILITTKKGKAgiqkiTFSSNLTVdhaiclpefqnSYamdpe 374
Cdd:COG4773 138 ---------------LERVEVLKGPAGL-LYGAGSPGGLVNLVTKRPTA-----EPQGEVSL-----------SA----- 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 375 akNGWGKKATLKDYD---NADNFFQ---NGVTAiNSVSFMNGSEKMQTYFSyanttakGIVEknkmqkhnlnFRETANff 448
Cdd:COG4773 181 --GSWDTYRATADVGgplNEDGTLRyrlNAAYE-DGDSFRDGVDNRRTLIA-------PSLD----------WDLTDD-- 238
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 449 ndylkLDANVNLMTQTIKNRPTSGGYymnPLVG-LYGFPRGedlseyknnfevfdpaRNMNvQNWytSYQDMEQNpywit 527
Cdd:COG4773 239 -----TTLTLGAEYQDDDSTGDRGFL---PLDGtLLDLPRS----------------TNLG-EPW--DYYDTETT----- 286
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 528 nrinsndkrtraIASLTANVKITDWLNIQARGT-ADYTHDQYQQRMYASTAPALSGQNGRYIDLNHTETLYYGDVMAMIn 606
Cdd:COG4773 287 ------------TLFAELEHRFNDDWSLRANARySDSDRDGRSAYAYGAPDAATGTLTRYASARDGDSRSDSLDANLNG- 353
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 607 kkwnDFSLNG-----AIGGSINSTNVNSLRLDSKTASLYYPNVFTVANIKmTQAAYIDEQINQkrvlQSLFGTAQLGWKE 681
Cdd:COG4773 354 ----KFETGGlehtlLVGADYSRYDSDSDSATAGTINIYNPVYGNLPEPD-FDASDTDTTTRQ----TGLYAQDQISLTD 424
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 682 SLYLDVTARNDW--------SSTLAYTKHSSFFYPSVGLSWvlnntvKLPEWISfgkIRGSWSKVgndlplFISNTIPGS 753
Cdd:COG4773 425 RLSLLLGGRYDWyetdstnrLGGSTTSYDDSAFTPRAGLVY------DLTPGLS---LYASYSES------FEPQSGADN 489
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 754 NDiigaggaivtyskapfNDLKPEMSTSYEIGTEWKFFNYRLDFDFTYYRTNTKNQLFTLPSSAGaeykyYMVNAGNIQN 833
Cdd:COG4773 490 NG----------------NPLDPETGKQYEAGVKGELFDGRLNATLAVFDITQKNVATTDPDNPN-----FYVQVGEVRS 548
|
730 740 750
....*....|....*....|....*....|....
gi 1650039217 834 EGIEITLGATPVMNdafrWKIQFNFSTNKNKIIK 867
Cdd:COG4773 549 RGVELELSGELTPG----LNLIAGYTYTDAKITK 578
|
|
| TonB-hemlactrns |
TIGR01786 |
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ... |
190-864 |
6.54e-12 |
|
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273808 [Multi-domain] Cd Length: 715 Bit Score: 69.75 E-value: 6.54e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 190 EQVVVTAMGIKKKEASLTYSTQQ----VGGDELTRaKDPNMINALAGKTAGVQItkSSSGLGGSAKVSIRGSrsisGNNQ 265
Cdd:TIGR01786 1 DTITVTATRTADPQRRDLSVTPAsvsvISREQLKS-QQVRNLRDLLRYEPGVSV--VEGGRGGSQGINIRGL----DKNR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 266 PLYVIDGVPmlnssneQASTAIGGTADAGnrdggdGISNLNPDDIESMSILKGASAAaLYGSQAANGVILITTKKGKagi 345
Cdd:TIGR01786 74 VAVLVDGIR-------QNTSYGGQGSTFY------AINSIDPELIKSIEIVKGASSS-LYGSGALGGVVAFRTKDAA--- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 346 qkitfssnltvDHaicLPEFQNSYAMdpeAKNGwgkkatlkdYDNADNFFQNGVTAinsvsfmNGSEKMQTYFSYANTTa 425
Cdd:TIGR01786 137 -----------DL---LKPGKDLGGL---SKLG---------YSSANNRFTQSVAA-------AGRNDDVDALVQATYR- 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 426 kgiveknkmqkhnlNFRETANFfndylkLDANVNLMTQTIKnrPTSGGYYMNPLVGLYG--FPRGEDLSEYKNNFEVFDP 503
Cdd:TIGR01786 183 --------------RGHELKNG------NKANIGNESKRSK--PNPSDYKSQSFLAKLGwqLNDAHRLGLSLEYTQTDYD 240
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 504 ARNMNVQNWYTSyQDMEQNPYWitnRINSNDKRTRAiASLTANVKI---TDWLNiQARGTADYTH---DQYQQRMYASTA 577
Cdd:TIGR01786 241 EPEMTNTSYLTK-PLGAPLLSS---TVVLGDSKTRD-RRTGLDYELnpdNSWLD-TVKLALDKQYiqlYNYLNATSASDY 314
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 578 PALSgQNGRYIDLNHtetLYYGDVMAMINKKWNDFSLNGAIGGSINSTNVNslrldsktaslyYPNVF-TVANIKMTQAA 656
Cdd:TIGR01786 315 PGVD-KNGRYKDKYD---YYTLGFDTNNKIEFSVHSLSLTYGLDRFKDKVS------------TGDSRrNLPTAAYNLYG 378
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 657 YIDEQINQKRVLQSLFGTAQLGWKESLYLDVTARNDWSST----------LAYTKHSSFFYPSVGLSWVLNntvklPEWI 726
Cdd:TIGR01786 379 YEGENRPVKGSNFGLFLQDNIKLGDWLSLSAGLRYDHYKTdpkadeskdyGAISKTYSRWSPSLGLTYKPT-----PWLT 453
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 727 SFGKIRGSWSkVGNDLPLFISntipgsndiiGAGGAIVTYSKAPFNDLKPEMSTSYEIGtewkfFNYR---LDFDFTYYR 803
Cdd:TIGR01786 454 LYYSYSQGFR-APSFDELYGT----------GAHPGGGPYTFLPNPNLKPETSKNWEIG-----INLHfdqLDFKVSYFR 517
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1650039217 804 TNTKNQLFTLPSSAGAEYK--------YYMVNAGNIQNEGIEIT----LGATPVMNDAFRWKIQFNFSTNKNK 864
Cdd:TIGR01786 518 NDYKDFIDLGIGVTAKGNMaqvgsntiTNYVNIDNARIRGIELSgrydLGSFFSGPDGWTTTLKYGYTKGKDS 590
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
531-867 |
6.54e-11 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 66.44 E-value: 6.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 531 NSNDKRTRAIASLTANVKITDWLNIQAR-GTADYTHDQYQQRMYASTAPALSGQNGRYIDlnHTETLYYGDVMAMINKKW 609
Cdd:COG4774 220 DDYSDSETDSATLRLEHDFNDNWTLRNAlRYSDYDRDYRNTYPTGGNATGTVTRSAYRRD--QDNDTLSNQTDLTGKFDT 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 610 NDFSLNGAIGGSINSTNVNSLRLDSK----TASLYYPNVFTVANIKMTQAAYIDEQINQkrvlQSLFGTAQLGWKESLYL 685
Cdd:COG4774 298 GGVKHTLLAGVEYSREDSDNARYSGGgtapTVNLYNPVYGAPVTGPTLGGADNDSRTDT----TGLYLQDTISLTDRWSL 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 686 DVTARNDW---------SSTLAYTKHSSFFYPSVGLSWvlnntvKLPEWISFgkiRGSWSKvgndlplfiSNTIPGSNDI 756
Cdd:COG4774 374 LAGLRYDRfdtdytdrtTGATTSSYDDSAFSPRAGLVY------KPTPNLSL---YASYST---------SFNPGGGAPS 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 757 IGAGGAivtyskapfnDLKPEMSTSYEIGTEWKFFNYRLDFDFTYYRTNTKNQLFTLPSSAGaeykyYMVNAGNIQNEGI 836
Cdd:COG4774 436 LSNAGQ----------ALDPEKSRQYEVGVKWDLLDGRLSLTAALFRIEKTNVRTTDPANPG-----VYVQTGEQRSRGV 500
|
330 340 350
....*....|....*....|....*....|.
gi 1650039217 837 EITLGATPVmndaFRWKIQFNFSTNKNKIIK 867
Cdd:COG4774 501 ELEATGELT----PGWSVLAGYTYLDAEITK 527
|
|
| TonB-hemin |
TIGR01785 |
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ... |
189-864 |
2.18e-10 |
|
TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273807 [Multi-domain] Cd Length: 665 Bit Score: 64.72 E-value: 2.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 189 LEQVVVTAMGIKKKEASLTYSTQQVGGDELTRaKDPNMINALAGKTAGVQITksSSGLGGSAKVSIRGSrsisGNNQPLY 268
Cdd:TIGR01785 1 LDTVTVTATRTRQVLSEAPASVSVISGEQIES-KQANNLADALNTVPGVDVT--GGGRPPGQSINIRGL----QDNRVLV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 269 VIDGVPMlnssneqastaiGGTADAGNrdggDGISNLNPDDIESMSILKGASAAaLYGSQAANGVILITTKKGKAGIQ-- 346
Cdd:TIGR01785 74 VVDGARQ------------NYQRGGAH----NGSLFVDPELLKRIEIVKGPSSS-LYGSGALGGVVAFRTKDAADLLRpg 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 347 -------KITFSSNltvDHaiclpEFQNSYAmdpeakngwgkkATLKDYDNADNFFQNGVTAINSVSFMNGSEKMQTYFS 419
Cdd:TIGR01785 137 qlfgglaKLSYGSN---NN-----SFGGSVA------------VAGRLDDNLDALVAATYRDGGNYRNGNKEEATNSAYV 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 420 YANTTAKGIVEKNkmQKHNLNFretaNFFNDYLKLDANVNLMTQTiKNRPTSGgyymnplVGLYGfprgedlseyknnfe 499
Cdd:TIGR01785 197 QKNLLAKLGWQLD--DAQRLEF----SYFTTEGSLDEAQNSGPGT-EYVLGSS-------STLLA--------------- 247
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 500 vfDPARNMNVQnwYTSYQDMEQNPYWitnrinsndkrtRAIASLTANVKITDWLNIQARGTADYThdqYQQRMYASTApa 579
Cdd:TIGR01785 248 --SSTRDRSAT--LTYNWTPEDNPWL------------DATASLYYNRTENDNDRSARGVGREEG---YQYTTYGATL-- 306
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 580 lsgQNGRYIDLNHTETLYYGdvmaminkkwNDFSLNGAIGGSINSTNVNSLRLDSKTASLYYPNVFTVANIKMtqaayid 659
Cdd:TIGR01785 307 ---QNTSRFDVASWSTLTYG----------VDWMKDKRRTESFDPNSVTTIVPNPPSAKEYFFGLFLQDNIPL------- 366
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 660 eqinqkrvlqslfgtaqlgWKESLYLDVTARNDW--------SSTLAYTKHSSFFYPSVGLSWVLnntvkLPEWISFGKI 731
Cdd:TIGR01785 367 -------------------LDDRLTLSAGLRYDHyklspkttADTEAVDRSYSRWSPSLGLSYKP-----VDWLTLYASY 422
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 732 RGSWSKvgndlplfisntiPGSNDIIGAG---GAIVTYSKAPFNDLKPEMSTSYEIGTEWKFFNY-----RLDFDFTYYR 803
Cdd:TIGR01785 423 SQGFRA-------------PSIDELYGTGdhpGTPGGYTFAPNPNLKPETSKTWELGANLSFDNLlldndQLQFKVAYFY 489
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1650039217 804 TNTKN-----QLFTLPSSAGAEYKYYMVNAGNIQNEGIEITLgatpvMNDAFRWKIQFNFSTNKNK 864
Cdd:TIGR01785 490 NDVKDfidltIGVTDNVTAGMNNITQYVNIDGARIRGIEASA-----SYDAGLWATGLSYGYTIGK 550
|
|
| CarboxypepD_reg |
pfam13620 |
Carboxypeptidase regulatory-like domain; |
113-182 |
7.33e-09 |
|
Carboxypeptidase regulatory-like domain;
Pssm-ID: 433354 [Multi-domain] Cd Length: 81 Bit Score: 53.44 E-value: 7.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 113 TVKGVVTDQNGDPIIGANV----LEKGTTNGCITNMEGNFSL-NVPSNSI-LTITYIGYHPQ-----NIQVNGQQNLNIK 181
Cdd:pfam13620 1 TISGTVTDPSGAPVPGATVtvtnTDTGTVRTTTTDADGRYRFpGLPPGTYtVTVSAPGFKTAtrtgvTVTAGQTTTLDVT 80
|
.
gi 1650039217 182 M 182
Cdd:pfam13620 81 L 81
|
|
| STN |
pfam07660 |
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ... |
51-99 |
4.61e-08 |
|
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.
Pssm-ID: 429580 [Multi-domain] Cd Length: 51 Bit Score: 50.21 E-value: 4.61e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1650039217 51 FVYNKKNVDTRRTVNVQADNKAVSEVLDEAFKGTNIKYVMEGHNIVLTK 99
Cdd:pfam07660 2 ILYDSDLVDGKQSVSLNVGNVTLEEALDQLLAGTGLSYEIGGNTIVLRP 50
|
|
| PRK13486 |
PRK13486 |
TonB-dependent receptor; |
186-442 |
1.69e-05 |
|
TonB-dependent receptor;
Pssm-ID: 139606 [Multi-domain] Cd Length: 696 Bit Score: 48.86 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 186 AMALEQVVVTAMGIKKKEASLTYSTQQVGGDELTRAKDPNMINALAGkTAGVQItKSSSGLGGSAKVSIRGSRSisgnNQ 265
Cdd:PRK13486 22 AAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRS-VEGVDV-ESGTGKTGGLEISIRGMPA----SY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 266 PLYVIDGVPMlnssneqastaiGGTADAGNrdggDGISNLNPD------DIESMSILKGAsAAALYGSQAANGVILITTK 339
Cdd:PRK13486 96 TLILIDGVRQ------------GGSSDVTP----NGFSAMNTGfmpplaAIERIEVIRGP-MSTLYGSDAMGGVVNIITR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 340 KGKagiQKITFSSNLTVDhaiclpeFQNSyamdpeakNGWGKKATLkdydnadNFFQNGVTAINSVSF-MNGSEKMQ--- 415
Cdd:PRK13486 159 KNA---DKWLSSVNAGLN-------LQES--------NKWGNSSQF-------NFWSSGPLVDDSVSLqVRGSTQQRqgs 213
|
250 260
....*....|....*....|....*..
gi 1650039217 416 TYFSYANTTAKGIVEKNKMQKHNLNFR 442
Cdd:PRK13486 214 SVTSLSDTAATRIPYPTESQNYNLGAR 240
|
|
| PRK10064 |
PRK10064 |
catecholate siderophore receptor CirA; Provisional |
189-360 |
5.98e-05 |
|
catecholate siderophore receptor CirA; Provisional
Pssm-ID: 236646 [Multi-domain] Cd Length: 663 Bit Score: 47.19 E-value: 5.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 189 LEQVVVTAMGIKKKEASLTYSTQQVGGDELTRAKDPNMINALaGKTAGVQITKSSSGLGGsakVSIRGSRSisgnNQPLY 268
Cdd:PRK10064 30 GETMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVL-KEVPGVQLTNEGDNRKG---VSIRGLDS----SYTLI 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 269 VIDGvPMLNSSNeqastaiggtadAGNRdGGDGISNLNP-DDIESMSILKGAsAAALYGSQAANGVILITTKK-GKAgiq 346
Cdd:PRK10064 102 LIDG-KRVNSRN------------AVFR-HNDFDLNWIPvDAIERIEVVRGP-MSSLYGSDALGGVVNIITKKiGQK--- 163
|
170
....*....|....
gi 1650039217 347 kitFSSNLTVDHAI 360
Cdd:PRK10064 164 ---WHGTVTVDTTI 174
|
|
| PRK13524 |
PRK13524 |
FepA family TonB-dependent siderophore receptor; |
184-341 |
1.61e-04 |
|
FepA family TonB-dependent siderophore receptor;
Pssm-ID: 237410 [Multi-domain] Cd Length: 744 Bit Score: 45.79 E-value: 1.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 184 EEAMALEQVVVTAMGIKKKEASLTYSTQqvggDELTRAKDPNMINALAGKTAGVQIT-KSSSG-LGGSAKVSIRGSrsis 261
Cdd:PRK13524 33 TPASHEDTIVVTAAEQNLQAPGVSTITA----EDIRKRPPANDVSEIIRTMPGVNLTgNSTSGqRGNNRQIDIRGM---- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 262 GNNQPLYVIDGVPmLNSSNeqaSTAIGGtadAGNRDG-GDgiSN-LNPDDIESMSILKGAsAAALYGSQAANGVILITTK 339
Cdd:PRK13524 105 GPENTLILIDGKP-VSSRN---SVRYGW---RGERDTrGD--TNwVPPEMIERIEVLRGP-AAARYGNGAAGGVVNIITK 174
|
..
gi 1650039217 340 KG 341
Cdd:PRK13524 175 KP 176
|
|
| PRK13528 |
PRK13528 |
outer membrane receptor FepA; Provisional |
211-340 |
2.61e-04 |
|
outer membrane receptor FepA; Provisional
Pssm-ID: 237413 [Multi-domain] Cd Length: 727 Bit Score: 45.13 E-value: 2.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 211 QQVGGDELTR---AKDP--NMINALAGKTAGVQIT-KSSSGL-GGSAKVSIRGSrsisGNNQPLYVIDGVPmLNSSNeqa 283
Cdd:PRK13528 49 QQPGVSIITAediKKRPpvNDLSDIIRKMPGVNLTgNSASGTrGNNRQIDIRGM----GPENTLILIDGVP-VTSRN--- 120
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1650039217 284 STAIGGTADAGNRdgGDgiSN-LNPDDIESMSILKGAsAAALYGSQAANGVILITTKK 340
Cdd:PRK13528 121 SVRYSWRGERDTR--GD--TNwVPPEMVERIEVIRGP-AAARYGSGAAGGVVNIITKR 173
|
|
| STN |
smart00965 |
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ... |
49-97 |
5.96e-04 |
|
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.
Pssm-ID: 198033 [Multi-domain] Cd Length: 52 Bit Score: 38.64 E-value: 5.96e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1650039217 49 YLFVYNKKNVdTRRTVNVQADNKAVSEVLDEAFKGTNIKYVMEGHNIVL 97
Cdd:smart00965 1 LNFVYDPALV-AGRRVSLLLGNVTVEQALDRLLAGTGLTYRRIGGNTIV 48
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
261-838 |
9.52e-04 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 43.17 E-value: 9.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 261 SGNNQPLYVIDGVPMlnssneqaSTAIGGTADAGNRDGGD-GISNLNPDDIESMSILKGAsAAALYGSQAANGVILITTK 339
Cdd:TIGR01783 39 GTTQFGNITIRGFGL--------EVDIDNVYLDGVPLLSRgNLAIVDPAMVERVEVLRGP-ASLLYGGSAPGGVINIVTK 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 340 KGKAgiqkiTFSSNLTVdhaiclpefqnsyamdpeakngwgkkatlkdydNADNFFQNGVTAINSVSFmNGSEKMQTYFS 419
Cdd:TIGR01783 110 RPQD-----EPKGSVTF---------------------------------GAGTRSGYRTAFDLGGPL-GADGTFRGRLN 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 420 YANTTAKGIVEKnkmQKHNLNFRETANffndYLKLDANVNLMTQTIKNRPTSGGYYmnplvglYGFPRGEDLSEYKNNFE 499
Cdd:TIGR01783 151 GARQDGDSFYDG---AGEETRLGATAT----DWQLDDRTLLRLGAYYQKERDRGGY-------GGLPASGGTSGRDLSSD 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 500 vfdpaRNMNVQNWyTSYQDMEQNPYWITNRINSNDKRTRaiaSLTANVKITDWLNIQARGTAdYTHDQYQQRMYASTAPa 579
Cdd:TIGR01783 217 -----RYLGTSSN-RNYDDREYLSYGLSLEYQFNDVWTG---KQNLRYSYFDTDSNQVQASG-YSSDGGLFGRSLTVVN- 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 580 lSGQNGRYIDLNhtetlYYGDVM-AMINkkwNDFSLNGAIGGSINSTNVNSLRLDSKTaslYYPNVFTVANIKMTQAAYI 658
Cdd:TIGR01783 286 -VKQDRVQIDAG-----LDGEFEtGPIE---HDLLLGVSYGQRTTNRFNNTGYPSDNI---YSLTATSSARTDIGDSPKD 353
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 659 DEQINQKRVLQSLFGTAQLGWkESLYLDVTARNDW--------SSTLAYTKHSSFFYPSVGLSWvlnntvKLPEWISFGK 730
Cdd:TIGR01783 354 RALSSTTKALNGVALQRILLA-DKWTLTLGGRYDSvdvksnngVAGSTGKRDDSQFTPSLGVAY------KPTDDWSLYA 426
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 731 IRGSWSKVGNDLPLFISNtipgSNDIigaggaivtyskapfndLKPEMSTSYEIGTEWKFFNYRLdFDFTYYRTNTKNQL 810
Cdd:TIGR01783 427 SYAESFKPGGYYPKGAGN----SGDI-----------------LEPEKGKNYELGVRYDLGDSLL-ATAALFRITKDNQL 484
|
570 580
....*....|....*....|....*...
gi 1650039217 811 FTLPSSAgaeykYYMVNAGNIQNEGIEI 838
Cdd:TIGR01783 485 VQDPVNG-----TFSVNAGKTRNRGVEL 507
|
|
| PRK13528 |
PRK13528 |
outer membrane receptor FepA; Provisional |
773-864 |
1.29e-03 |
|
outer membrane receptor FepA; Provisional
Pssm-ID: 237413 [Multi-domain] Cd Length: 727 Bit Score: 42.82 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1650039217 773 DLKPEMSTSYEIGTEWKFFNYRLdfDFTYYRTNTKNQLFtlpssAGAEYKYYMVNAGNI---QN------EGIEITLgAT 843
Cdd:PRK13528 518 NLDPEISVNKEIGLEFTVDDYHA--SVTYFRNDYQNKIV-----AGDDVIGRTASGAYIlqwQNggkavvEGLEGNL-LV 589
|
90 100
....*....|....*....|..
gi 1650039217 844 PVMNDAFRWKIQFNFS-TNKNK 864
Cdd:PRK13528 590 PLMKDRLNWNTNATYMiTSEQK 611
|
|
| Peptidase_M14NE-CP-C_like |
cd11308 |
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, ... |
114-173 |
4.36e-03 |
|
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; This domain is found C-terminal to the M14 carboxypeptidase (CP) N/E subfamily containing zinc-binding enzymes that hydrolyze single C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. The N/E subfamily includes enzymatically active members (carboxypeptidase N, E, M, D, and Z), as well as non-active members (carboxypeptidase-like protein 1, -2, aortic CP-like protein, and adipocyte enhancer binding protein-1) which lack the critical active site and substrate-binding residues considered necessary for activity. The active N/E enzymes fulfill a variety of cellular functions, including prohormone processing, regulation of peptide hormone activity, alteration of protein-protein or protein-cell interactions and transcriptional regulation. For M14 CPs, it has been suggested that this domain may assist in folding of the CP domain, regulate enzyme activity, or be involved in interactions with other proteins or with membranes; for carboxypeptidase M, it may interact with the bradykinin 1 receptor at the cell surface. This domain may also be found in other peptidase families.
Pssm-ID: 200604 [Multi-domain] Cd Length: 76 Bit Score: 37.12 E-value: 4.36e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1650039217 114 VKGVVTDQNGDPIIGANVLEKGTTNGCITNMEGNF-SLNVPSNSILTITYIGYHP--QNIQVN 173
Cdd:cd11308 2 IKGFVTDATGNPIANATISVEGINHDVTTAKDGDYwRLLLPGTYNVTASAPGYQPvtKTVTVP 64
|
|
| |
