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Conserved domains on  [gi|12232485|ref|NP_073626.1|]
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interleukin-25 isoform 1 precursor

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
IL17 super family cl05558
Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T ...
84-172 4.18e-26

Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T cells. The IL-17 family is thought to represent a distinct signaling system that appears to have been highly conserved across vertebrate evolution.


The actual alignment was detected with superfamily member pfam06083:

Pssm-ID: 253550  Cd Length: 84  Bit Score: 96.63  E-value: 4.18e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12232485    84 SRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQTGSHMDpRGNSELLYHNQTVFYRRPchgeKGTHKGYCLERRLYR 163
Cdd:pfam06083   1 NRSLSPWTYEISHDPNRYPSVLPEAKCLCRGCINAQTGEEDF-SMNSVPIYQEILVLRRTP----PPTGGRYSFRLEKVT 75

                  ....*....
gi 12232485   164 VSLACVCVR 172
Cdd:pfam06083  76 VTVGCTCVP 84
 
Name Accession Description Interval E-value
IL17 pfam06083
Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T ...
84-172 4.18e-26

Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T cells. The IL-17 family is thought to represent a distinct signaling system that appears to have been highly conserved across vertebrate evolution.


Pssm-ID: 253550  Cd Length: 84  Bit Score: 96.63  E-value: 4.18e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12232485    84 SRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQTGSHMDpRGNSELLYHNQTVFYRRPchgeKGTHKGYCLERRLYR 163
Cdd:pfam06083   1 NRSLSPWTYEISHDPNRYPSVLPEAKCLCRGCINAQTGEEDF-SMNSVPIYQEILVLRRTP----PPTGGRYSFRLEKVT 75

                  ....*....
gi 12232485   164 VSLACVCVR 172
Cdd:pfam06083  76 VTVGCTCVP 84
 
Name Accession Description Interval E-value
IL17 pfam06083
Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T ...
84-172 4.18e-26

Interleukin-17; IL-17 is a potent proinflammatory cytokine produced by activated memory T cells. The IL-17 family is thought to represent a distinct signaling system that appears to have been highly conserved across vertebrate evolution.


Pssm-ID: 253550  Cd Length: 84  Bit Score: 96.63  E-value: 4.18e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12232485    84 SRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQTGSHMDpRGNSELLYHNQTVFYRRPchgeKGTHKGYCLERRLYR 163
Cdd:pfam06083   1 NRSLSPWTYEISHDPNRYPSVLPEAKCLCRGCINAQTGEEDF-SMNSVPIYQEILVLRRTP----PPTGGRYSFRLEKVT 75

                  ....*....
gi 12232485   164 VSLACVCVR 172
Cdd:pfam06083  76 VTVGCTCVP 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.14
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2015), "CDD: NCBI's conserved domain database.", Nucleic Acids Res.43(D)222-6.
  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A et al. (2009), "CDD: specific functional annotation with the Conserved Domain Database.", Nucleic Acids Res.37(D)205-10.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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