|
Name |
Accession |
Description |
Interval |
E-value |
| fabF |
TIGR03150 |
beta-ketoacyl-acyl-carrier-protein synthase II; 3-oxoacyl-[acyl-carrier-protein] synthase 2 ... |
4-409 |
0e+00 |
|
beta-ketoacyl-acyl-carrier-protein synthase II; 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis]
Pssm-ID: 274452 [Multi-domain] Cd Length: 407 Bit Score: 728.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 4 KRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELFPAKVAAEINDFEVEKYIDKKEARRMDRFTQYAVAAAK 83
Cdd:TIGR03150 1 RRVVVTGLGAVTPLGNGVEEFWENLLAGKSGIGPITRFDASDLPVKIAGEVKDFDPEDYIDKKEARRMDRFIQYALAAAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 84 MAVADAKLEITEENGPRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKGINTCSVTA 163
Cdd:TIGR03150 81 EAVEDSGLDIEEEDAERVGVIIGSGIGGLETIEEQHIVLLEKGPRRVSPFFIPMSIINMAAGQISIRYGAKGPNHAVVTA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 164 CASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKAL-TFNEDPATACRPFDKNRSGFVMGEGSGILILEE 242
Cdd:TIGR03150 161 CATGTHAIGDAFRLIQRGDADVMIAGGAEAAITPLGIAGFAAMKALsTRNDDPEKASRPFDKDRDGFVMGEGAGVLVLEE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 243 LEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKETF 322
Cdd:TIGR03150 241 LEHAKARGAKIYAEIVGYGMSGDAYHITAPAPEGEGAARAMRAALKDAGINPEDVDYINAHGTSTPLGDKAETKAIKKVF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 323 GEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNARHQEVNAVLSNSLGFGGH 402
Cdd:TIGR03150 321 GDHAYKLAVSSTKSMTGHLLGAAGAIEAIFTVLAIRDGIVPPTINLDNPDPECDLDYVPNEAREAKIDYALSNSFGFGGT 400
|
....*..
gi 721831997 403 NAVLVFK 409
Cdd:TIGR03150 401 NASLVFK 407
|
|
| PRK07314 |
PRK07314 |
beta-ketoacyl-ACP synthase II; |
3-412 |
0e+00 |
|
beta-ketoacyl-ACP synthase II;
Pssm-ID: 235987 [Multi-domain] Cd Length: 411 Bit Score: 718.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 3 KKRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELFPAKVAAEINDFEVEKYIDKKEARRMDRFTQYAVAAA 82
Cdd:PRK07314 1 KRRVVVTGLGAVSPLGNDVESTWKNLLAGKSGIGPITHFDTSDLAVKIAGEVKDFNPDDYMSRKEARRMDRFIQYGIAAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 83 KMAVADAKLEITEENGPRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKGINTCSVT 162
Cdd:PRK07314 81 KQAVEDAGLEITEENADRIGVIIGSGIGGLETIEEQHITLLEKGPRRVSPFFVPMAIINMAAGHVSIRYGAKGPNHSIVT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 163 ACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKAL-TFNEDPATACRPFDKNRSGFVMGEGSGILILE 241
Cdd:PRK07314 161 ACATGAHAIGDAARLIAYGDADVMVAGGAEAAITPLGIAGFAAARALsTRNDDPERASRPFDKDRDGFVMGEGAGILVLE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 242 ELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKET 321
Cdd:PRK07314 241 ELEHAKARGAKIYAEVVGYGMTGDAYHMTAPAPDGEGAARAMKLALKDAGINPEDIDYINAHGTSTPAGDKAETQAIKRV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 322 FGEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNARHQEVNAVLSNSLGFGG 401
Cdd:PRK07314 321 FGEHAYKVAVSSTKSMTGHLLGAAGAVEAIFSVLAIRDQVIPPTINLDNPDEECDLDYVPNEARERKIDYALSNSFGFGG 400
|
410
....*....|.
gi 721831997 402 HNAVLVFKSYK 412
Cdd:PRK07314 401 TNASLVFKRYE 411
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
4-411 |
0e+00 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 691.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 4 KRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELFPAKVAAEINDFEVEKYIDKKEARRMDRFTQYAVAAAK 83
Cdd:COG0304 1 RRVVITGLGAVSPLGNGVEEFWEALLAGRSGIRPITRFDASGLPVRIAGEVKDFDPEEYLDRKELRRMDRFTQYALAAAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 84 MAVADAKLEITEENGPRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKGINTCSVTA 163
Cdd:COG0304 81 EALADAGLDLDEVDPDRTGVIIGSGIGGLDTLEEAYRALLEKGPRRVSPFFVPMMMPNMAAGHVSIRFGLKGPNYTVSTA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 164 CASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKAL-TFNEDPATACRPFDKNRSGFVMGEGSGILILEE 242
Cdd:COG0304 161 CASGAHAIGEAYRLIRRGRADVMIAGGAEAAITPLGLAGFDALGALsTRNDDPEKASRPFDKDRDGFVLGEGAGVLVLEE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 243 LEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKETF 322
Cdd:COG0304 241 LEHAKARGAKIYAEVVGYGASSDAYHITAPAPDGEGAARAMRAALKDAGLSPEDIDYINAHGTSTPLGDAAETKAIKRVF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 323 GEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNARHQEVNAVLSNSLGFGGH 402
Cdd:COG0304 321 GDHAYKVPVSSTKSMTGHLLGAAGAIEAIASVLALRDGVIPPTINLENPDPECDLDYVPNEAREAKIDYALSNSFGFGGH 400
|
....*....
gi 721831997 403 NAVLVFKSY 411
Cdd:COG0304 401 NASLVFKRY 409
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
4-408 |
0e+00 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 638.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 4 KRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELFPAKVAAEINDFEVEKYIDKKEARRMDRFTQYAVAAAK 83
Cdd:cd00834 1 RRVVITGLGAVTPLGNGVEEFWEALLAGRSGIRPITRFDASGFPSRIAGEVPDFDPEDYLDRKELRRMDRFAQFALAAAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 84 MAVADAKLEITEENGPRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKGINTCSVTA 163
Cdd:cd00834 81 EALADAGLDPEELDPERIGVVIGSGIGGLATIEEAYRALLEKGPRRVSPFFVPMALPNMAAGQVAIRLGLRGPNYTVSTA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 164 CASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKAL-TFNEDPATACRPFDKNRSGFVMGEGSGILILEE 242
Cdd:cd00834 161 CASGAHAIGDAARLIRLGRADVVIAGGAEALITPLTLAGFAALRALsTRNDDPEKASRPFDKDRDGFVLGEGAGVLVLES 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 243 LEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKETF 322
Cdd:cd00834 241 LEHAKARGAKIYAEILGYGASSDAYHITAPDPDGEGAARAMRAALADAGLSPEDIDYINAHGTSTPLNDAAESKAIKRVF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 323 GEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNARHQEVNAVLSNSLGFGGH 402
Cdd:cd00834 321 GEHAKKVPVSSTKSMTGHLLGAAGAVEAIATLLALRDGVLPPTINLEEPDPECDLDYVPNEAREAPIRYALSNSFGFGGH 400
|
....*.
gi 721831997 403 NAVLVF 408
Cdd:cd00834 401 NASLVF 406
|
|
| PRK06333 |
PRK06333 |
beta-ketoacyl-ACP synthase; |
1-412 |
0e+00 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235781 [Multi-domain] Cd Length: 424 Bit Score: 515.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 1 MEKKRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELFPAKVAAEIND--------FEVEKYIDKKEARRMD 72
Cdd:PRK06333 1 MNKKRIVVTGMGAVSPLGCGVETFWQRLLAGQSGIRTLTDFPVGDLATKIGGQVPDlaedaeagFDPDRYLDPKDQRKMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 73 RFTQYAVAAAKMAVADAKLEITEENGP-RIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIAT 151
Cdd:PRK06333 81 RFILFAMAAAKEALAQAGWDPDTLEDReRTATIIGSGVGGFPAIAEAVRTLDSRGPRRLSPFTIPSFLTNMAAGHVSIRY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 152 GAKGINTCSVTACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALT--FNEDPATACRPFDKNRSGF 229
Cdd:PRK06333 161 GFKGPLGAPVTACAAGVQAIGDAARLIRSGEADVAVCGGTEAAIDRVSLAGFAAARALStrFNDAPEQASRPFDRDRDGF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 230 VMGEGSGILILEELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDA 309
Cdd:PRK06333 241 VMGEGAGILVIETLEHALARGAPPLAELVGYGTSADAYHMTAGPEDGEGARRAMLIALRQAGIPPEEVQHLNAHATSTPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 310 NEKYETMAIKETFGeHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECD-LDYVPNNARHQE 388
Cdd:PRK06333 321 GDLGEVAAIKKVFG-HVSGLAVSSTKSATGHLLGAAGGVEAIFTILALRDQIAPPTLNLENPDPAAEgLDVVANKARPMD 399
|
410 420
....*....|....*....|....
gi 721831997 389 VNAVLSNSLGFGGHNAVLVFKSYK 412
Cdd:PRK06333 400 MDYALSNGFGFGGVNASILFRRWE 423
|
|
| PRK08439 |
PRK08439 |
3-oxoacyl-(acyl carrier protein) synthase II; Reviewed |
4-411 |
2.97e-171 |
|
3-oxoacyl-(acyl carrier protein) synthase II; Reviewed
Pssm-ID: 236265 [Multi-domain] Cd Length: 406 Bit Score: 485.01 E-value: 2.97e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 4 KRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELFPAKVAAEINDFEVEKYIDKKEARRMDRFTQYAVAAAK 83
Cdd:PRK08439 2 KRVVVTGIGMINSLGLNKESSFKAICNGECGIKKITLFDASDFPVQIAGEITDFDPTEVMDPKEVKKADRFIQLGLKAAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 84 MAVADAKLEITEENGPRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKGINTCSVTA 163
Cdd:PRK08439 82 EAMKDAGFLPEELDAERFGVSSASGIGGLPNIEKNSIICFEKGPRKISPFFIPSALVNMLGGFISIEHGLKGPNLSSVTA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 164 CASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKAL-TFNEDPATACRPFDKNRSGFVMGEGSGILILEE 242
Cdd:PRK08439 162 CAAGTHAIIEAVKTIMLGGADKMLVVGAESAICPVGIGGFAAMKALsTRNDDPKKASRPFDKDRDGFVMGEGAGALVLEE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 243 LEHALARGAHIYAEIAGYGATGDAFHITMPAPggEGGVRAMRQALADAGLQPedIDYINAHGTSTDANEKYETMAIKETF 322
Cdd:PRK08439 242 YESAKKRGAKIYAEIIGFGESGDANHITSPAP--EGPLRAMKAALEMAGNPK--IDYINAHGTSTPYNDKNETAALKELF 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 323 GEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNARHQEVNAVLSNSLGFGGH 402
Cdd:PRK08439 318 GSKEKVPPVSSTKGQIGHCLGAAGAIEAVISIMAMRDGILPPTINQETPDPECDLDYIPNVARKAELNVVMSNSFGFGGT 397
|
....*....
gi 721831997 403 NAVLVFKSY 411
Cdd:PRK08439 398 NGVVIFKKV 406
|
|
| PTZ00050 |
PTZ00050 |
3-oxoacyl-acyl carrier protein synthase; Provisional |
13-411 |
9.52e-166 |
|
3-oxoacyl-acyl carrier protein synthase; Provisional
Pssm-ID: 240245 [Multi-domain] Cd Length: 421 Bit Score: 471.48 E-value: 9.52e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 13 AVTPVGTDVETAWENIKKGVSGIGRLTRID----------------PELFPAKVAAEInDFEVEKYIDKKEARRMDRFTQ 76
Cdd:PTZ00050 1 VVTPLGVGAESTWEALIAGKSGIRKLTEFPkflpdcipeqkalenlVAAMPCQIAAEV-DQSEFDPSDFAPTKRESRATH 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 77 YAVAAAKMAVADAKLEITEENGP-RIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKG 155
Cdd:PTZ00050 80 FAMAAAREALADAKLDILSEKDQeRIGVNIGSGIGSLADLTDEMKTLYEKGHSRVSPYFIPKILGNMAAGLVAIKHKLKG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 156 INTCSVTACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALT--FNEDPATACRPFDKNRSGFVMGE 233
Cdd:PTZ00050 160 PSGSAVTACATGAHCIGEAFRWIKYGEADIMICGGTEASITPVSFAGFSRMRALCtkYNDDPQRASRPFDKDRAGFVMGE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 234 GSGILILEELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQP-EDIDYINAHGTSTDANEK 312
Cdd:PTZ00050 240 GAGILVLEELEHALRRGAKIYAEIRGYGSSSDAHHITAPHPDGRGARRCMENALKDGANINiNDVDYVNAHATSTPIGDK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 313 YETMAIKETFGEH-AYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNARH--QEV 389
Cdd:PTZ00050 320 IELKAIKKVFGDSgAPKLYVSSTKGGLGHLLGAAGAVESIVTILSLYEQIIPPTINLENPDAECDLNLVQGKTAHplQSI 399
|
410 420
....*....|....*....|..
gi 721831997 390 NAVLSNSLGFGGHNAVLVFKSY 411
Cdd:PTZ00050 400 DAVLSTSFGFGGVNTALLFTKY 421
|
|
| PRK08722 |
PRK08722 |
beta-ketoacyl-ACP synthase II; |
1-409 |
1.61e-148 |
|
beta-ketoacyl-ACP synthase II;
Pssm-ID: 181539 [Multi-domain] Cd Length: 414 Bit Score: 427.50 E-value: 1.61e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 1 MEKKRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELFPAKVAAEINDFEVEKYIDKKEARRMDRFTQYAVA 80
Cdd:PRK08722 1 MSKRRVVVTGMGMLSPVGNTVESSWKALLAGQSGIVNIEHFDTTNFSTRFAGLVKDFNCEEYMSKKDARKMDLFIQYGIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 81 AAKMAVADAKLEITEENGPRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKGINTCS 160
Cdd:PRK08722 81 AGIQALDDSGLEVTEENAHRIGVAIGSGIGGLGLIEAGHQALVEKGPRKVSPFFVPSTIVNMIAGNLSIMRGLRGPNIAI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 161 VTACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKAL-TFNEDPATACRPFDKNRSGFVMGEGSGILI 239
Cdd:PRK08722 161 STACTTGLHNIGHAARMIAYGDADAMVAGGAEKASTPLGMAGFGAAKALsTRNDEPQKASRPWDKDRDGFVLGDGAGMMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 240 LEELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIK 319
Cdd:PRK08722 241 LEEYEHAKARGAKIYAELVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDAGVTGEQIGYVNAHGTSTPAGDVAEIKGIK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 320 ETFGEH-AYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNARHQE-VNAVLSNSL 397
Cdd:PRK08722 321 RALGEAgSKQVLVSSTKSMTGHLLGAAGSVEAIITVMSLVDQIVPPTINLDDPEEGLDIDLVPHTARKVEsMEYAICNSF 400
|
410
....*....|..
gi 721831997 398 GFGGHNAVLVFK 409
Cdd:PRK08722 401 GFGGTNGSLIFK 412
|
|
| PLN02836 |
PLN02836 |
3-oxoacyl-[acyl-carrier-protein] synthase |
4-410 |
2.94e-146 |
|
3-oxoacyl-[acyl-carrier-protein] synthase
Pssm-ID: 215449 [Multi-domain] Cd Length: 437 Bit Score: 422.66 E-value: 2.94e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 4 KRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPEL--------------FPAKVAAEI------NDFEVEKYI 63
Cdd:PLN02836 6 RRVVVTGLGLVTPLGCGVETTWRRLIAGECGVRALTQDDLKMksedeetqlytldqLPSRVAALVprgtgpGDFDEELWL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 64 dkkEARRMDRFTQYAVAAAKMAVADAKLEITE-ENGPRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDM 142
Cdd:PLN02836 86 ---NSRSSSRFIGYALCAADEALSDARWLPSEdEAKERTGVSIGGGIGSITDILEAAQLICEKRLRRLSPFFVPRILINM 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 143 AAGQVSIATGAKGINTCSVTACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALT--FNEDPATACR 220
Cdd:PLN02836 163 AAGHVSIRYGFQGPNHAAVTACATGAHSIGDAFRMIQFGDADVMVAGGTESSIDALSIAGFSRSRALStkFNSCPTEASR 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 221 PFDKNRSGFVMGEGSGILILEELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYI 300
Cdd:PLN02836 243 PFDCDRDGFVIGEGAGVLVLEELEHAKRRGAKIYAEVRGYGMSGDAHHITQPHEDGRGAVLAMTRALQQSGLHPNQVDYV 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 301 NAHGTSTDANEKYETMAIKETFGEHAY--KVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLD 378
Cdd:PLN02836 323 NAHATSTPLGDAVEARAIKTVFSEHATsgGLAFSSTKGATGHLLGAAGAVEAIFSVLAIHHGIAPPTLNLERPDPIFDDG 402
|
410 420 430
....*....|....*....|....*....|...
gi 721831997 379 YVP-NNARHQEVNAVLSNSLGFGGHNAVLVFKS 410
Cdd:PLN02836 403 FVPlTASKAMLIRAALSNSFGFGGTNASLLFTS 435
|
|
| PLN02787 |
PLN02787 |
3-oxoacyl-[acyl-carrier-protein] synthase II |
1-412 |
9.05e-115 |
|
3-oxoacyl-[acyl-carrier-protein] synthase II
Pssm-ID: 215421 [Multi-domain] Cd Length: 540 Bit Score: 345.81 E-value: 9.05e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 1 MEKKRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELFPAKVAAEINDFEVEKYIDKKEARRMDRFTQYAVA 80
Cdd:PLN02787 126 TKQRRVVVTGMGVVSPLGHDPDVFYNNLLEGVSGISEIERFDCSQFPTRIAGEIKSFSTDGWVAPKLSKRMDKFMLYLLT 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 81 AAKMAVADAKleITEE-----NGPRIGVWIGSGIGGMETYEEQFKIFtEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKG 155
Cdd:PLN02787 206 AGKKALADGG--ITEDvmkelDKTKCGVLIGSAMGGMKVFNDAIEAL-RISYRKMNPFCVPFATTNMGSAMLAMDLGWMG 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 156 INTCSVTACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALT-FNEDPATACRPFDKNRSGFVMGEG 234
Cdd:PLN02787 283 PNYSISTACATSNFCILNAANHIIRGEADVMLCGGSDAAIIPIGLGGFVACRALSqRNDDPTKASRPWDMNRDGFVMGEG 362
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 235 SGILILEELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYE 314
Cdd:PLN02787 363 AGVLLLEELEHAKKRGANIYAEFLGGSFTCDAYHMTEPHPEGAGVILCIEKALAQSGVSKEDVNYINAHATSTKAGDLKE 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 315 TMAIKETFGEHAyKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLD-YVPNNARHQEVNAVL 393
Cdd:PLN02787 443 YQALMRCFGQNP-ELRVNSTKSMIGHLLGAAGAVEAIATVQAIRTGWVHPNINLENPESGVDTKvLVGPKKERLDIKVAL 521
|
410
....*....|....*....
gi 721831997 394 SNSLGFGGHNAVLVFKSYK 412
Cdd:PLN02787 522 SNSFGFGGHNSSILFAPYK 540
|
|
| PRK07910 |
PRK07910 |
beta-ketoacyl-ACP synthase; |
6-411 |
3.03e-107 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 236129 [Multi-domain] Cd Length: 418 Bit Score: 322.45 E-value: 3.03e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 6 VVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELF--PAKVAAEINDfEVEKYIDKKEARRMDRFTQYAVAAAK 83
Cdd:PRK07910 14 VVVTGIAMTTALATDAETTWKLLLDGQSGIRTLDDPFVEEFdlPVRIGGHLLE-EFDHQLTRVELRRMSYLQRMSTVLGR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 84 MAVADAKLEITEENgpRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKGINTCSVTA 163
Cdd:PRK07910 93 RVWENAGSPEVDTN--RLMVSIGTGLGSAEELVFAYDDMRARGLRAVSPLAVQMYMPNGPAAAVGLERHAKAGVITPVSA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 164 CASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKAL--TFNEDPATACRPFDKNRSGFVMGEGSGILILE 241
Cdd:PRK07910 171 CASGSEAIAQAWRQIVLGEADIAICGGVETRIEAVPIAGFAQMRIVmsTNNDDPAGACRPFDKDRDGFVFGEGGALMVIE 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 242 ELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKET 321
Cdd:PRK07910 251 TEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAMTRAIELAGLTPGDIDHVNAHATGTSVGDVAEGKAINNA 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 322 FGEHayKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNARHQEVNAVLSNSLGFGG 401
Cdd:PRK07910 331 LGGH--RPAVYAPKSALGHSVGAVGAVESILTVLALRDGVIPPTLNLENLDPEIDLDVVAGEPRPGNYRYAINNSFGFGG 408
|
410
....*....|
gi 721831997 402 HNAVLVFKSY 411
Cdd:PRK07910 409 HNVALAFGRY 418
|
|
| PRK06501 |
PRK06501 |
beta-ketoacyl-ACP synthase; |
6-412 |
1.76e-106 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235817 [Multi-domain] Cd Length: 425 Bit Score: 320.81 E-value: 1.76e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 6 VVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELFPAKVAAEINDFEVEKYIDKKEARRMDRFTqyavaaAKMA 85
Cdd:PRK06501 13 VAVTGMGVVTSLGQGKADNWAALTAGESGIHTITRFPTEGLRTRIAGTVDFLPESPFGASALSEALARLA------AEEA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 86 VADAKLEITEENGP--------------RIGVWIGSGIGGMETYEEQFKIfteKGPRRVSPFFVPMMIPDMAAgQVSIAT 151
Cdd:PRK06501 87 LAQAGIGKGDFPGPlflaappvelewpaRFALAAAVGDNDAPSYDRLLRA---ARGGRFDALHERFQFGSIAD-RLADRF 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 152 GAKGINTCSVTACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKAL-TFNEDPATACRPFDKNRSGFV 230
Cdd:PRK06501 163 GTRGLPISLSTACASGATAIQLGVEAIRRGETDRALCIATDGSVSAEALIRFSLLSALsTQNDPPEKASKPFSKDRDGFV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 231 MGEGSGILILEELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDAN 310
Cdd:PRK06501 243 MAEGAGALVLESLESAVARGAKILGIVAGCGEKADSFHRTRSSPDGSPAIGAIRAALADAGLTPEQIDYINAHGTSTPEN 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 311 EKYETMAIKETFGEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNARHQEVN 390
Cdd:PRK06501 323 DKMEYLGLSAVFGERLASIPVSSNKSMIGHTLTAAGAVEAVFSLLTIQTGRLPPTINYDNPDPAIPLDVVPNVARDARVT 402
|
410 420
....*....|....*....|..
gi 721831997 391 AVLSNSLGFGGHNAVLVFKSYK 412
Cdd:PRK06501 403 AVLSNSFGFGGQNASLVLTAEP 424
|
|
| PRK07967 |
PRK07967 |
beta-ketoacyl-ACP synthase I; |
4-412 |
1.23e-105 |
|
beta-ketoacyl-ACP synthase I;
Pssm-ID: 181184 [Multi-domain] Cd Length: 406 Bit Score: 317.77 E-value: 1.23e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 4 KRVVITGLGAVTPVGTDVETAWENIKKGVSGIgrltRIDPEL----FPAKVAAEInDFEVEKYIDKKEARRMDRFTQYAV 79
Cdd:PRK07967 2 RRVVITGLGIVSSIGNNQQEVLASLREGRSGI----TFSPEFaemgMRSQVWGNV-KLDPTGLIDRKVMRFMGDASAYAY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 80 AAAKMAVADAKLEITEENGPRIGVWIGSGIGGMETYEEQFKIF-TEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKGINT 158
Cdd:PRK07967 77 LAMEQAIADAGLSEEQVSNPRTGLIAGSGGGSTRNQVEAADAMrGPRGPKRVGPYAVTKAMASTVSACLATPFKIKGVNY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 159 CSVTACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAgFSSAKALT--FNEDPATACRPFDKNRSGFVMGEGSG 236
Cdd:PRK07967 157 SISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELDWEMSCL-FDAMGALStkYNDTPEKASRAYDANRDGFVIAGGGG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 237 ILILEELEHALARGAHIYAEIAGYGATGDAFhiTMPAPGGEGGVRAMRQALADAGlqpEDIDYINAHGTSTDANEKYETM 316
Cdd:PRK07967 236 VVVVEELEHALARGAKIYAEIVGYGATSDGY--DMVAPSGEGAVRCMQMALATVD---TPIDYINTHGTSTPVGDVKELG 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 317 AIKETFGEHAykVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPE-CDLDYVPNNARHQEVNAVLSN 395
Cdd:PRK07967 311 AIREVFGDKS--PAISATKSLTGHSLGAAGVQEAIYSLLMMEHGFIAPSANIEELDPQaAGMPIVTETTDNAELTTVMSN 388
|
410
....*....|....*..
gi 721831997 396 SLGFGGHNAVLVFKSYK 412
Cdd:PRK07967 389 SFGFGGTNATLVFRRYK 405
|
|
| PRK09116 |
PRK09116 |
beta-ketoacyl-ACP synthase; |
4-409 |
8.86e-104 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 181657 [Multi-domain] Cd Length: 405 Bit Score: 313.08 E-value: 8.86e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 4 KRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRID--PELfPAKVAAEINDFEVEKYIDKKEARRMDRFTQYAVAA 81
Cdd:PRK09116 2 RRVVVTGMGGVTALGEDWQTIAARLKAGRNAVRRMPEWDryDGL-NTRLAAPIDDFELPAHYTRKKIRSMGRVSLMATRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 82 AKMAVADAKL----EITeeNGpRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSP-FFVPMMiPDMAAGQVSIATGAKG- 155
Cdd:PRK09116 81 SELALEDAGLlgdpILT--DG-RMGIAYGSSTGSTDPIGAFGTMLLEGSMSGITAtTYVRMM-PHTTAVNVGLFFGLKGr 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 156 -INTCSvtACASGANSIGDAFKAIQRGDADAMITGGAEApLTSMAFAGFSSAKAL-TFNEDPATACRPFDKNRSGFVMGE 233
Cdd:PRK09116 157 vIPTSS--ACTSGSQGIGYAYEAIKYGYQTVMLAGGAEE-LCPTEAAVFDTLFATsTRNDAPELTPRPFDANRDGLVIGE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 234 GSGILILEELEHALARGAHIYAEIAGYGATGDAFHITMPAPggEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKY 313
Cdd:PRK09116 234 GAGTLVLEELEHAKARGATIYAEIVGFGTNSDGAHVTQPQA--ETMQIAMELALKDAGLAPEDIGYVNAHGTATDRGDIA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 314 ETMAIKETFGEhayKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPEC-DLDYVPNNARHQEVNAV 392
Cdd:PRK09116 312 ESQATAAVFGA---RMPISSLKSYFGHTLGACGALEAWMSIEMMNEGWFAPTLNLTQVDPACgALDYIMGEAREIDTEYV 388
|
410
....*....|....*..
gi 721831997 393 LSNSLGFGGHNAVLVFK 409
Cdd:PRK09116 389 MSNNFAFGGINTSLIFK 405
|
|
| PRK14691 |
PRK14691 |
3-oxoacyl-(acyl carrier protein) synthase II; Provisional |
96-411 |
1.49e-99 |
|
3-oxoacyl-(acyl carrier protein) synthase II; Provisional
Pssm-ID: 173154 [Multi-domain] Cd Length: 342 Bit Score: 300.11 E-value: 1.49e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 96 ENGPRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKGINTCSVTACASGANSIGDAF 175
Cdd:PRK14691 23 EKQERTATIIGAGIGGFPAIAHAVRTSDSRGPKRLSPFTVPSFLVNLAAGHVSIKHHFKGPIGAPVTACAAGVQAIGDAV 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 176 KAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALT--FNEDPATACRPFDKNRSGFVMGEGSGILILEELEHALARGAHI 253
Cdd:PRK14691 103 RMIRNNEADVALCGGAEAVIDTVSLAGFAAARALSthFNSTPEKASRPFDTARDGFVMGEGAGLLIIEELEHALARGAKP 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 254 YAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKETFGEhAYKVAISS 333
Cdd:PRK14691 183 LAEIVGYGTSADAYHMTSGAEDGDGAYRAMKIALRQAGITPEQVQHLNAHATSTPVGDLGEINAIKHLFGE-SNALAITS 261
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 721831997 334 TKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECD-LDYVPNNARHQEVNAVLSNSLGFGGHNAVLVFKSY 411
Cdd:PRK14691 262 TKSATGHLLGAAGGLETIFTVLALRDQIVPATLNLENPDPAAKgLNIIAGNAQPHDMTYALSNGFGFAGVNASILLKRW 340
|
|
| PRK05952 |
PRK05952 |
beta-ketoacyl-ACP synthase; |
5-407 |
3.12e-84 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235653 [Multi-domain] Cd Length: 381 Bit Score: 262.30 E-value: 3.12e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 5 RVVITGLGAVTPVGtDVETAWENIKKGVSGIgRLTRIDPELfPAKVAAEINDFEVEkyidkkearrmdrFTQYAVAAAKM 84
Cdd:PRK05952 3 KVVVTGIGLVSALG-DLEQSWQRLLQGKSGI-KLHQPFPEL-PPLPLGLIGNQPSS-------------LEDLTKTVVTA 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 85 AVADAKLEITEengPRIGVWIGSGIGGMETYEEQFK-IFTEKGPRRVSPFFVPMM--IPDMAAGQVSIATGAKGINTCSV 161
Cdd:PRK05952 67 ALKDAGLTPPL---TDCGVVIGSSRGCQGQWEKLARqMYQGDDSPDEELDLENWLdtLPHQAAIAAARQIGTQGPVLAPM 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 162 TACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALTfnedpATACRPFDKNRSGFVMGEGSGILILE 241
Cdd:PRK05952 144 AACATGLWAIAQGVELIQTGQCQRVIAGAVEAPITPLTLAGFQQMGALA-----KTGAYPFDRQREGLVLGEGGAILVLE 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 242 ELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKET 321
Cdd:PRK05952 219 SAELAQKRGAKIYGQILGFGLTCDAYHMSAPEPDGKSAIAAIQQCLARSGLTPEDIDYIHAHGTATRLNDQREANLIQAL 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 322 FGEhayKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETpdPECDLDYVpNNARHQEVNAVLSNSLGFGG 401
Cdd:PRK05952 299 FPH---RVAVSSTKGATGHTLGASGALGVAFSLLALRHQQLPPCVGLQE--PEFDLNFV-RQAQQSPLQNVLCLSFGFGG 372
|
....*.
gi 721831997 402 HNAVLV 407
Cdd:PRK05952 373 QNAAIA 378
|
|
| CLF |
cd00832 |
Chain-length factor (CLF) is a factor required for polyketide chain initiation of aromatic ... |
4-407 |
6.11e-83 |
|
Chain-length factor (CLF) is a factor required for polyketide chain initiation of aromatic antibiotic-producing polyketide synthases (PKSs) of filamentous bacteria. CLFs have been shown to have decarboxylase activity towards malonyl-acyl carrier protein (ACP). CLFs are similar to other elongation ketosynthase domains, but their active site cysteine is replaced by a conserved glutamine.
Pssm-ID: 238428 [Multi-domain] Cd Length: 399 Bit Score: 259.60 E-value: 6.11e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 4 KRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELFPAKVAAEINDFEVEKYIDKKEARRMDRFTQYAVAAAK 83
Cdd:cd00832 1 RRAVVTGIGVVAPNGLGVEEYWKAVLDGRSGLGPITRFDPSGYPARLAGEVPDFDAAEHLPGRLLPQTDRMTRLALAAAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 84 MAVADAKLEITEENGPRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKGINTCSVTA 163
Cdd:cd00832 81 WALADAGVDPAALPPYDMGVVTASAAGGFEFGQRELQKLWSKGPRHVSAYQSFAWFYAVNTGQISIRHGMRGPSGVVVAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 164 CASGANSIGDAFKAIQRGdADAMITGGAEAPLTSMAFAGFSSAKALTFNEDPATACRPFDKNRSGFVMGEGSGILILEEL 243
Cdd:cd00832 161 QAGGLDALAQARRLVRRG-TPLVVSGGVDSALCPWGWVAQLSSGRLSTSDDPARAYLPFDAAAAGYVPGEGGAILVLEDA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 244 EHALARGAHIYAEIAGYGATGDAfhitMPAPGGEGG-VRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKETF 322
Cdd:cd00832 240 AAARERGARVYGEIAGYAATFDP----PPGSGRPPGlARAIRLALADAGLTPEDVDVVFADAAGVPELDRAEAAALAAVF 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 323 GEHAykVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNARHQEVNAVLSNSLGFGGH 402
Cdd:cd00832 316 GPRG--VPVTAPKTMTGRLYAGGAPLDVATALLALRDGVIPPTVNVTDVPPAYGLDLVTGRPRPAALRTALVLARGRGGF 393
|
....*
gi 721831997 403 NAVLV 407
Cdd:cd00832 394 NSALV 398
|
|
| elong_cond_enzymes |
cd00828 |
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
5-407 |
6.35e-83 |
|
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP) thioesters as primer substrates, as well as the nature of their active site residues.
Pssm-ID: 238424 [Multi-domain] Cd Length: 407 Bit Score: 259.68 E-value: 6.35e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 5 RVVITGLGAVTPVGT---DVETAWENIKKGVSGIGRLTRIDPElFPAKVAAEINDFEVEKYIDKKEaRRMDRFTQYAVAA 81
Cdd:cd00828 2 RVVITGIGVVSPHGEgcdEVEEFWEALREGRSGIAPVARLKSR-FDRGVAGQIPTGDIPGWDAKRT-GIVDRTTLLALVA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 82 AKMAVADAKLEI-TEENGPRIGVWIGSGIGGMETYEEQFKIFTEKGPRRVSPFFvpMMIPDMAAGQVSIA-TGAKGINTC 159
Cdd:cd00828 80 TEEALADAGITDpYEVHPSEVGVVVGSGMGGLRFLRRGGKLDARAVNPYVSPKW--MLSPNTVAGWVNILlLSSHGPIKT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 160 SVTACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFaGFSSAKALTFNED-PATACRPFDKNRSGFVMGEGSGIL 238
Cdd:cd00828 158 PVGACATALEALDLAVEAIRSGKADIVVVGGVEDPLEEGLS-GFANMGALSTAEEePEEMSRPFDETRDGFVEAEGAGVL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 239 ILEELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGeGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAI 318
Cdd:cd00828 237 VLERAELALARGAPIYGRVAGTASTTDGAGRSVPAGGK-GIARAIRTALAKAGLSLDDLDVISAHGTSTPANDVAESRAI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 319 KETFGEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNAR--HQEVNAVLSNS 396
Cdd:cd00828 316 AEVAGALGAPLPVTAQKALFGHSKGAAGALQLIGALQSLEHGLIPPTANLDDVDPDVEHLSVVGLSRdlNLKVRAALVNA 395
|
410
....*....|.
gi 721831997 397 LGFGGHNAVLV 407
Cdd:cd00828 396 FGFGGSNAALV 406
|
|
| PRK09185 |
PRK09185 |
beta-ketoacyl-ACP synthase; |
100-408 |
2.57e-75 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 236398 [Multi-domain] Cd Length: 392 Bit Score: 239.36 E-value: 2.57e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 100 RIGVWIG---SGIGGMETYEEQFKIFTEKGPrrvSPFFVPMMIPDMAAGQVSIATGAKG-INTCSvTACASGANSIGDAF 175
Cdd:PRK09185 96 RIGVVLGtstSGILEGELAYRRRDPAHGALP---ADYHYAQQELGSLADFLRAYLGLSGpAYTIS-TACSSSAKVFASAR 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 176 KAIQRGDADAMITGGAEApLTSMAFAGFSSAKALTfnedpATACRPFDKNRSGFVMGEGSGILILE-ELEHALArgahiy 254
Cdd:PRK09185 172 RLLEAGLCDAAIVGGVDS-LCRLTLNGFNSLESLS-----PQPCRPFSANRDGINIGEAAAFFLLErEDDAAVA------ 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 255 aeIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKETFGEHaykVAISST 334
Cdd:PRK09185 240 --LLGVGESSDAHHMSAPHPEGLGAILAMQQALADAGLAPADIGYINLHGTATPLNDAMESRAVAAVFGDG---VPCSST 314
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 721831997 335 KSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNNARHQEVNAVLSNSLGFGGHNAVLVF 408
Cdd:PRK09185 315 KGLTGHTLGAAGAVEAAICWLALRHGLPPHGWNTGQPDPALPPLYLVENAQALAIRYVLSNSFAFGGNNCSLIF 388
|
|
| PRK07103 |
PRK07103 |
polyketide beta-ketoacyl:acyl carrier protein synthase; Validated |
3-407 |
5.04e-75 |
|
polyketide beta-ketoacyl:acyl carrier protein synthase; Validated
Pssm-ID: 180839 [Multi-domain] Cd Length: 410 Bit Score: 239.16 E-value: 5.04e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 3 KKRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLTRIDPELF--------PAKVAAEINDFEVEKYIDKKEARRMDRF 74
Cdd:PRK07103 1 MDEVVVTGVGVVSAIGQGRPSFAAALLAGRHAFGVMRRPGRQVPddagaglaSAFIGAELDSLALPERLDAKLLRRASLS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 75 TQYAVAAAKMAVADAKLEitEENGPRIGVWI-GSGIGGMETYEeQFKIFTEKgPRRVSP-FFVPMMIPDmAAGQVSIATG 152
Cdd:PRK07103 81 AQAALAAAREAWRDAALG--PVDPDRIGLVVgGSNLQQREQAL-VHETYRDR-PAFLRPsYGLSFMDTD-LVGLCSEQFG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 153 AKGInTCSV-TACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKAL---TFNEDPATACRPFDKNRSG 228
Cdd:PRK07103 156 IRGE-GFTVgGASASGQLAVIQAARLVQSGSVDACIAVGALMDLSYWECQALRSLGAMgsdRFADEPEAACRPFDQDRDG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 229 FVMGEGSGILILEELEHALARGAHIYAEIAGYGATGDAFHitMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTD 308
Cdd:PRK07103 235 FIYGEACGAVVLESAESARRRGARPYAKLLGWSMRLDANR--GPDPSLEGEMRVIRAALRRAGLGPEDIDYVNPHGTGSP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 309 ANEKYETMAIketFGEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETP-DPECdlDYVPNNARHQ 387
Cdd:PRK07103 313 LGDETELAAL---FASGLAHAWINATKSLTGHGLSAAGIVELIATLLQMRAGFLHPSRNLDEPiDERF--RWVGSTAESA 387
|
410 420
....*....|....*....|
gi 721831997 388 EVNAVLSNSLGFGGHNAVLV 407
Cdd:PRK07103 388 RIRYALSLSFGFGGINTALV 407
|
|
| PKS |
cd00833 |
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different ... |
5-407 |
1.51e-66 |
|
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.
Pssm-ID: 238429 [Multi-domain] Cd Length: 421 Bit Score: 217.81 E-value: 1.51e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 5 RVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLT--RIDPELFPAKVAA-------------EINDFEVEKY-IDKKEA 68
Cdd:cd00833 2 PIAIVGMACRFPGAADPDEFWENLLEGRDAISEIPedRWDADGYYPDPGKpgktytrrggfldDVDAFDAAFFgISPREA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 69 RRMD---RFtqyavaaakmavadaKLEITEE------------NGPRIGVWIGSGiggMETYEEQFKifteKGPRRVSPF 133
Cdd:cd00833 82 EAMDpqqRL---------------LLEVAWEaledagyspeslAGSRTGVFVGAS---SSDYLELLA----RDPDEIDAY 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 134 FVPMMIPDMAAGQVSIATGAKGiNTCSV-TACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALTfn 212
Cdd:cd00833 140 AATGTSRAFLANRISYFFDLRG-PSLTVdTACSSSLVALHLACQSLRSGECDLALVGGVNLILSPDMFVGFSKAGMLS-- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 213 edPATACRPFDKNRSGFVMGEGSGILILEELEHALARGAHIYAEIAGYGAT--GDAFHITmpAPGGEGGVRAMRQALADA 290
Cdd:cd00833 217 --PDGRCRPFDADADGYVRGEGVGVVVLKRLSDALRDGDRIYAVIRGSAVNqdGRTKGIT--APSGEAQAALIRRAYARA 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 291 GLQPEDIDYINAHGTSTDANEKYETMAIKETFGEHAYK---VAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTIN 367
Cdd:cd00833 293 GVDPSDIDYVEAHGTGTPLGDPIEVEALAKVFGGSRSAdqpLLIGSVKSNIGHLEAAAGLAGLIKVVLALEHGVIPPNLH 372
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 721831997 368 YETPDPECDLD----YVPNNARHQEVNAVLS----NSLGFGGHNAVLV 407
Cdd:cd00833 373 FETPNPKIDFEesplRVPTEARPWPAPAGPRragvSSFGFGGTNAHVI 420
|
|
| decarbox_cond_enzymes |
cd00825 |
decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new ... |
91-407 |
2.60e-57 |
|
decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new carbon-carbon bond by a decarboxylating Claisen-like condensation reaction. Members are involved in the synthesis of fatty acids and polyketides, a diverse group of natural products. Both pathways are an iterative series of additions of small carbon units, usually acetate, to a nascent acyl group. There are 2 classes of decarboxylating condensing enzymes, which can be distinguished by sequence similarity, type of active site residues and type of primer units (acetyl CoA or acyl carrier protein (ACP) linked units).
Pssm-ID: 238421 [Multi-domain] Cd Length: 332 Bit Score: 190.92 E-value: 2.60e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 91 LEITEENGPRIGVWIGSGIGGMEtyeeqFKIFTEKGPRRVSPFFVPMMIPDMAAGQVSIATGAKGINTCSVTACASGANS 170
Cdd:cd00825 28 LSREYQKNPIVGVVVGTGGGSPR-----FQVFGADAMRAVGPYVVTKAMFPGASGQIATPLGIHGPAYDVSAACAGSLHA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 171 IGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALTfnedPATACRPFDKNRSGFVMGEGSGILILEELEHALARG 250
Cdd:cd00825 103 LSLAADAVQNGKQDIVLAGGSEELAAPMDCEFDAMGALST----PEKASRTFDAAADGFVFGDGAGALVVEELEHALARG 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 251 AHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKETFGEHayKVA 330
Cdd:cd00825 179 AHIYAEIVGTAATIDGAGMGAFAPSAEGLARAAKEALAVAGLTVWDIDYLVAHGTGTPIGDVKELKLLRSEFGDK--SPA 256
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 721831997 331 ISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPecDLDYVPNNARHQEVNAVLSNSLGFGGHNAVLV 407
Cdd:cd00825 257 VSATKAMTGNLSSAAVVLAVDEAVLMLEHGFIPPSIHIEELDE--AGLNIVTETTPRELRTALLNGFGLGGTNATLV 331
|
|
| ketoacyl-synt |
pfam00109 |
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar ... |
4-246 |
3.35e-55 |
|
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains. The N-terminal domain contains most of the structures involved in dimer formation and also the active site cysteine.
Pssm-ID: 425468 [Multi-domain] Cd Length: 251 Bit Score: 182.83 E-value: 3.35e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 4 KRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRL--TRIDPELF---PAKVAAEI--------NDFEVEKY---IDKKE 67
Cdd:pfam00109 1 EPVAIVGMGCRFPGGNDPEEFWENLLEGRDGISEIpaDRWDPDKLydpPSRIAGKIytkwggldDIFDFDPLffgISPRE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 68 ARRMDRFTQYAVAAAKMAVADAKLEITEENGPRIGVWIGSGIGGmetYEEQFKIFTEKGPRRVSPFFVPMMiPDMAAGQV 147
Cdd:pfam00109 81 AERMDPQQRLLLEAAWEALEDAGITPDSLDGSRTGVFIGSGIGD---YAALLLLDEDGGPRRGSPFAVGTM-PSVIAGRI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 148 SIATGAKGINTCSVTACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALTFNEdpatACRPFDKNRS 227
Cdd:pfam00109 157 SYFLGLRGPSVTVDTACSSSLVAIHAAVQSIRSGEADVALAGGVNLLLTPLGFAGFSAAGMLSPDG----PCKAFDPFAD 232
|
250
....*....|....*....
gi 721831997 228 GFVMGEGSGILILEELEHA 246
Cdd:pfam00109 233 GFVRGEGVGAVVLKRLSDA 251
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
1-407 |
1.85e-50 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 183.15 E-value: 1.85e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 1 MEKKRVVITGLGAVTPVGTDVETAWENIKKGVSGIGRLT--RIDPELF--PAKVAA------------EINDFEVEKY-I 63
Cdd:COG3321 1 AADEPIAIIGMACRFPGADDPEEFWRNLRAGRDAITEVPadRWDADAYydPDPDAPgktyvrwggfldDVDEFDALFFgI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 64 DKKEARRMD---RFtqyavaaakmavadaKLEITEE------------NGPRIGVWIGSGiggMETYEeqfkIFTEKGPR 128
Cdd:COG3321 81 SPREAEAMDpqqRL---------------LLEVAWEaledagydpeslAGSRTGVFVGAS---SNDYA----LLLLADPE 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 129 RVSPFFVPMMIPDMAAGQVSIATGAKGINtCSV-TACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAK 207
Cdd:COG3321 139 AIDAYALTGNAKSVLAGRISYKLDLRGPS-VTVdTACSSSLVAVHLACQSLRSGECDLALAGGVNLMLTPESFILFSKGG 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 208 ALTfnedPATACRPFDKNRSGFVMGEGSGILILEELEHALARGAHIYAEIAGY-----GAT-GdafhITmpAPGGEGGVR 281
Cdd:COG3321 218 MLS----PDGRCRAFDADADGYVRGEGVGVVVLKRLSDALRDGDRIYAVIRGSavnqdGRSnG----LT--APNGPAQAA 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 282 AMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKETFGEHAYK---VAISSTKSMTGHLLGAAGA---VEAIFSIK 355
Cdd:COG3321 288 VIRRALADAGVDPATVDYVEAHGTGTPLGDPIEAAALTAAFGQGRPAdqpCAIGSVKSNIGHLEAAAGVaglIKAVLALR 367
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 721831997 356 SitdGVIPPTINYETPDPECDLD----YVPNNARHQEVN------AVlsNSLGFGGHNAVLV 407
Cdd:COG3321 368 H---GVLPPTLHFETPNPHIDFEnspfYVNTELRPWPAGggprraGV--SSFGFGGTNAHVV 424
|
|
| Ketoacyl-synt_C |
pfam02801 |
Beta-ketoacyl synthase, C-terminal domain; The structure of beta-ketoacyl synthase is similar ... |
254-369 |
1.93e-50 |
|
Beta-ketoacyl synthase, C-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains.
Pssm-ID: 426989 Cd Length: 118 Bit Score: 165.82 E-value: 1.93e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 254 YAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPEDIDYINAHGTSTDANEKYETMAIKETFGEHAYK--VAI 331
Cdd:pfam02801 1 YAVIKGSAVNHDGRHNGLTAPNGEGQARAIRRALADAGVDPEDVDYVEAHGTGTPLGDPIEAEALKRVFGSGARKqpLAI 80
|
90 100 110
....*....|....*....|....*....|....*...
gi 721831997 332 SSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYE 369
Cdd:pfam02801 81 GSVKSNIGHLEGAAGAAGLIKVVLALRHGVIPPTLNLE 118
|
|
| omega_3_PfaA |
TIGR02813 |
polyketide-type polyunsaturated fatty acid synthase PfaA; Members of the seed for this ... |
136-412 |
4.97e-35 |
|
polyketide-type polyunsaturated fatty acid synthase PfaA; Members of the seed for this alignment are involved in omega-3 polyunsaturated fatty acid biosynthesis, such as the protein PfaA from the eicosapentaenoic acid biosynthesis operon in Photobacterium profundum strain SS9. PfaA is encoded together with PfaB, PfaC, and PfaD, and the functions of the individual polypeptides have not yet been described. More distant homologs of PfaA, also included with the reach of this model, appear to be involved in polyketide-like biosynthetic mechanisms of polyunsaturated fatty acid biosynthesis, an alternative to the more familiar iterated mechanism of chain extension and desaturation, and in most cases are encoded near genes for homologs of PfaB, PfaC, and/or PfaD.
Pssm-ID: 274311 [Multi-domain] Cd Length: 2582 Bit Score: 137.83 E-value: 4.97e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 136 PMMIPDMAAGQVSIATGAKGINTCSVTACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALTFNEDp 215
Cdd:TIGR02813 178 PGSLGNVISGRIANRFDLGGMNCVVDAACAGSLAAIRMALSELLEGRSEMMITGGVCTDNSPFMYMSFSKTPAFTTNED- 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 216 ataCRPFDKNRSGFVMGEGSGILILEELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGGVRAMRQALADAGLQPE 295
Cdd:TIGR02813 257 ---IQPFDIDSKGMMIGEGIGMMALKRLEDAERDGDRIYAVIKGVGASSDGKFKSIYAPRPEGQAKALKRAYDDAGFAPH 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 296 DIDYINAHGTSTDANEKYETMAIKETFGE---HAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPD 372
Cdd:TIGR02813 334 TCGLIEAHGTGTAAGDVAEFGGLVSVFSQdndQKQHIALGSVKSQIGHTKSTAGTAGMIKAVLALHHKVLPPTINVDQPN 413
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 721831997 373 PECDLD----YVPNNAR--HQEVNAVLS----NSLGFGGHNAVLVFKSYK 412
Cdd:TIGR02813 414 PKLDIEnspfYLNTETRpwMQREDGTPRragiSSFGFGGTNFHMVLEEYS 463
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
143-407 |
1.00e-31 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 121.01 E-value: 1.00e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 143 AAGQVSIATGAKGINTCSVT-ACASGANSIGDAFKAIQRGDADAMITGGAEApltsmafagfssakaltfnedpatacrp 221
Cdd:cd00327 46 AAGQLAYHLGISGGPAYSVNqACATGLTALALAVQQVQNGKADIVLAGGSEE---------------------------- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 222 fdknrsgFVMGEGSGILILEELEHALARGAHIYAEIAGYGATGDAFHItMPAPGGEGGVRAMRQALADAGLQPEDIDYIN 301
Cdd:cd00327 98 -------FVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAATFDGASM-VPAVSGEGLARAARKALEGAGLTPSDIDYVE 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 302 AHGTSTDANEKYETMAIKETFGEHAykVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTinyetpdpecdldyvp 381
Cdd:cd00327 170 AHGTGTPIGDAVELALGLDPDGVRS--PAVSATLIMTGHPLGAAGLAILDELLLMLEHEFIPPT---------------- 231
|
250 260
....*....|....*....|....*.
gi 721831997 382 nnarHQEVNAVLSNSLGFGGHNAVLV 407
Cdd:cd00327 232 ----PREPRTVLLLGFGLGGTNAAVV 253
|
|
| PKS_KS |
smart00825 |
Beta-ketoacyl synthase; The structure of beta-ketoacyl synthase is similar to that of the ... |
162-407 |
2.84e-25 |
|
Beta-ketoacyl synthase; The structure of beta-ketoacyl synthase is similar to that of the thiolase family and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains.
Pssm-ID: 214836 [Multi-domain] Cd Length: 298 Bit Score: 104.33 E-value: 2.84e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 162 TACASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALTfnedPATACRPFDKNRSGFVMGEGSGILILE 241
Cdd:smart00825 95 TACSSSLVALHLACQSLRSGECDMALAGGVNLILSPDTFVGLSRAGMLS----PDGRCKTFDASADGYVRGEGVGVVVLK 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 242 ELEHALARGAHIYAEIAGYGATGDAFHITMPAPGGEGgvramrQaladaglqpedidyinahgtstdanekyetmaiket 321
Cdd:smart00825 171 RLSDALRDGDPILAVIRGSAVNQDGRSNGITAPSGPA------Q------------------------------------ 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 322 fgehaykVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLD----YVPNNARHQEVN------A 391
Cdd:smart00825 209 -------LLIGSVKSNIGHLEAAAGVAGLIKVVLALKHGVIPPTLHFETPNPHIDLEesplRVPTELTPWPPPgrprraG 281
|
250
....*....|....*.
gi 721831997 392 VlsNSLGFGGHNAVLV 407
Cdd:smart00825 282 V--SSFGFGGTNAHVI 295
|
|
| PRK06147 |
PRK06147 |
3-oxoacyl-(acyl carrier protein) synthase; Validated |
165-300 |
4.83e-06 |
|
3-oxoacyl-(acyl carrier protein) synthase; Validated
Pssm-ID: 235715 [Multi-domain] Cd Length: 348 Bit Score: 48.09 E-value: 4.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 165 ASGANSIGDAFKAIQRGDADAMITGGAEAPLTSMAFAGFSSAKALTFNEdpatacrpfdkNRSGFVMGEGSGILILEELE 244
Cdd:PRK06147 134 VSGAVALAQARRLIAAGGCPRVLVAGVDSLLTGPTLAHYEARDRLLTSQ-----------NSNGFIPGEAAAAVLLGRPA 202
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 721831997 245 HALARGAHIYA-----EIAGYGATGDAfhitmpaPG-GEGGVRAMRQALADAGLQPEDIDYI 300
Cdd:PRK06147 203 GGEAPGLPLLGlglgrEPAPVGESEDL-------PLrGDGLTQAIRAALAEAGCGLEDMDYR 257
|
|
| PRK06519 |
PRK06519 |
beta-ketoacyl-ACP synthase; |
144-345 |
1.61e-05 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235819 [Multi-domain] Cd Length: 398 Bit Score: 46.87 E-value: 1.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 144 AGQVSIATGAKGINTCSVTACASGANSIGDAFKAIQRGDADAMITGG---AEAP--LTSMAFAGFSSAKALTfnedPATA 218
Cdd:PRK06519 155 AGNISIVHKVTGSSRTFMGEESAGVSAIEIAFARIASGQSDHALVGGaynAERPdmLLLYELGGLLLKGGWA----PVWS 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 219 CRPFDKnrSGFVMGEGSGILILEELEHALARGAHIYAEIAGYgatgdafhITMPAPGGEGGVRA-MRQALADAGLQPEDI 297
Cdd:PRK06519 231 RGGEDG--GGFILGSGGAFLVLESREHAEARGARPYARISGV--------ESDRARRAPGDLEAsLERLLKPAGGLAAPT 300
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 721831997 298 DYINAhgtstdANEKYETMAIKETFGEHAYKVAISSTKSMTGHLLGAA 345
Cdd:PRK06519 301 AVISG------ATGAHPATAEEKAALEAALAGPVRGIGTLFGHTMEAQ 342
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
211-347 |
1.67e-04 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 43.54 E-value: 1.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 211 FNEDPATACRPFDKNRSGFV-------MGEGSGILILEELEHALARGAHIYAEIAGYG--ATGDAFHITMPApggeggvR 281
Cdd:PLN02644 223 FDPAKLRKLRPSFKEDGGSVtagnassISDGAAALVLVSGEKALELGLQVIAKIRGYAdaAQAPELFTTAPA-------L 295
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 721831997 282 AMRQALADAGLQPEDIDYInahgtstDANEKYETMAI--KETFGEHAYKVAISSTKSMTGHLLGAAGA 347
Cdd:PLN02644 296 AIPKALKHAGLEASQVDYY-------EINEAFSVVALanQKLLGLDPEKVNVHGGAVSLGHPIGCSGA 356
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
222-357 |
8.37e-04 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 41.48 E-value: 8.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 222 FDKNRSGFVMGEGSGI------LILEELEHALARGAHIYAEIAGYGATGdafhiTMPAPGGEGGVRAMRQALADAGLQPE 295
Cdd:PRK09051 236 FKKENGTVTAGNASGIndgaaaVVLAEADAAEARGLKPLARLVGYAHAG-----VDPEYMGIGPVPATQKALERAGLTVA 310
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 721831997 296 DIDYInahgtstDANEKY--ETMAIKETFGEHAYKV-----AISstksmTGHLLGAAGaveAIFSIKSI 357
Cdd:PRK09051 311 DLDVI-------EANEAFaaQACAVTRELGLDPAKVnpngsGIS-----LGHPVGATG---AIITVKAL 364
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
220-347 |
1.20e-03 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 40.91 E-value: 1.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 220 RP-FDKNrsGFVM-GEGSGI------LILEELEHALARGAHIYAEIAGYG-ATGDafhitmPAPGGEGGVRAMRQALADA 290
Cdd:PRK05790 233 RPaFDKD--GTVTaGNASGIndgaaaVVVMSEAKAKELGLTPLARIVSYAvAGVD------PAIMGIGPVPAIRKALEKA 304
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 721831997 291 GLQPEDIDYInahgtstDANEKYETMAI---KEtFGEHAYKV-----AISstksmTGHLLGAAGA 347
Cdd:PRK05790 305 GWSLADLDLI-------EINEAFAAQALaveKE-LGLDPEKVnvnggAIA-----LGHPIGASGA 356
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
234-300 |
1.62e-03 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 40.43 E-value: 1.62e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 721831997 234 GSGILILEELEHALARGAHIYAEIAGYGATGDAFHItMpapgGEGGVRAMRQALADAGLQPEDIDYI 300
Cdd:COG0183 251 GAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEI-M----GIGPVPATRKALARAGLTLDDIDLI 312
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
163-209 |
1.90e-03 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 40.05 E-value: 1.90e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 721831997 163 ACASGANSIGDAFKAIQRGDADAMITGGAEapltSMAFAGFSSAKAL 209
Cdd:COG0183 87 VCGSGLQAVALAAQAIAAGDADVVIAGGVE----SMSRAPMLLPKAR 129
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
234-300 |
3.94e-03 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 39.00 E-value: 3.94e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 721831997 234 GSGILILEELEHALARGAHIYAEIAGYGATGDAFHItMpapgGEGGVRAMRQALADAGLQPEDIDYI 300
Cdd:cd00751 247 GAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAI-M----GIGPVPAIPKALKRAGLTLDDIDLI 308
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
225-348 |
6.60e-03 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 38.60 E-value: 6.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 721831997 225 NRSGFVmgEGSGILILEELEHALARGAHIYAEIAGYGATGDAFHITMPAPggeggVRAMRQALADAGLQPEDIDYInahg 304
Cdd:PRK06025 270 NSSGVV--DGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTLMLNAP-----VPAAKKVLAKAGLTKDDIDLW---- 338
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 721831997 305 tstDANEKYETMAIK--ETFGEHAYKVAISSTKSMTGHLLGAAGAV 348
Cdd:PRK06025 339 ---EINEAFAVVAEKfiRDLDLDRDKVNVNGGAIALGHPIGATGSI 381
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
279-305 |
8.80e-03 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 37.78 E-value: 8.80e-03
10 20
....*....|....*....|....*...
gi 721831997 279 GVRAMRQALADAGLQPEDIDY-INAHGT 305
Cdd:COG0332 55 AVEAARKALEAAGIDPEDIDLiIVATVT 82
|
|
| |
