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Conserved domains on  [gi|341600024|emb|CCC62692|]
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conserved hypothetical protein [Mycobacterium tuberculosis variant bovis BCG str. Moreau RDJ]

Protein Classification

13E12 repeat family protein( domain architecture ID 11697)

13E12 repeat family protein is a DUF222 domain-containing protein; similar to Mycobacterium tuberculosis uncharacterized protein Rv0095c

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF222 super family cl03674
Domain of unknown function (DUF222); This family is often found associated to the N-terminus ...
 75-177 2.31e-15

Domain of unknown function (DUF222); This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.


The actual alignment was detected with superfamily member pfam02720:

Pssm-ID: 397024  Cd Length: 305  Bit Score: 73.93  E-value: 2.31e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 341600024   75 LRSLERLECLVRRLPAVGHTLINQLDTQASEEELGGT-LCCALANRLRITKPDAALRIADAADLGPRraltgeplapqLT 153
Cdd:pfam02720   1 LAALEELEAAARRLAAVGHLLINRLDEDGDWAEDGGEaVAAEVAAALRISRAEASRRVRYARALRER-----------LP 69

                          90       100
                  ....*....|....*....|....
gi 341600024  154 ATATAQRQGLIGEAHIKVIRALFR 177
Cdd:pfam02720  70 ATAAAFRAGRIDLRHVRVIVARTD 93
 
Name Accession Description Interval E-value
DUF222 pfam02720
Domain of unknown function (DUF222); This family is often found associated to the N-terminus ...
 75-177 2.31e-15

Domain of unknown function (DUF222); This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.


Pssm-ID: 397024  Cd Length: 305  Bit Score: 73.93  E-value: 2.31e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 341600024   75 LRSLERLECLVRRLPAVGHTLINQLDTQASEEELGGT-LCCALANRLRITKPDAALRIADAADLGPRraltgeplapqLT 153
Cdd:pfam02720   1 LAALEELEAAARRLAAVGHLLINRLDEDGDWAEDGGEaVAAEVAAALRISRAEASRRVRYARALRER-----------LP 69

                          90       100
                  ....*....|....*....|....
gi 341600024  154 ATATAQRQGLIGEAHIKVIRALFR 177
Cdd:pfam02720  70 ATAAAFRAGRIDLRHVRVIVARTD 93
 
Name Accession Description Interval E-value
DUF222 pfam02720
Domain of unknown function (DUF222); This family is often found associated to the N-terminus ...
 75-177 2.31e-15

Domain of unknown function (DUF222); This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.


Pssm-ID: 397024  Cd Length: 305  Bit Score: 73.93  E-value: 2.31e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 341600024   75 LRSLERLECLVRRLPAVGHTLINQLDTQASEEELGGT-LCCALANRLRITKPDAALRIADAADLGPRraltgeplapqLT 153
Cdd:pfam02720   1 LAALEELEAAARRLAAVGHLLINRLDEDGDWAEDGGEaVAAEVAAALRISRAEASRRVRYARALRER-----------LP 69

                          90       100
                  ....*....|....*....|....
gi 341600024  154 ATATAQRQGLIGEAHIKVIRALFR 177
Cdd:pfam02720  70 ATAAAFRAGRIDLRHVRVIVARTD 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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