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pfam12409: P5-ATPase 
P5-type ATPase cation transporter
This domain family is found in eukaryotes, and is typically between 110 and 126 amino acids in length. The family is found in association with pfam00122, pfam00702. P-type ATPases comprise a large superfamily of proteins, present in both prokaryotes and eukaryotes, that transport inorganic cations and other substrates across cell membranes.
Statistics
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PSSM-Id: 257032
View PSSM: pfam12409
Aligned: 66 rows
Threshold Bit Score: 48.3619
Threshold Setting Gi: 74862432
Created: 29-Mar-2013
Updated: 4-Apr-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam12409 is a member of the superfamily cl13797.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74755755    31 SV--SSV-RLSGYCGSPWRVIGYHVVVWMMAGIPLLLFRWKPLWGVRLRLRPCNLAHAETLVieIRDKEDsswQLFTVQV 107
gi 74697535    13 EK--PFI-SVEGRKRRIS-TGFYNVLCVLTLGGFHMVCRYLPKVKHFLLSSPCSLSDADCVI--VTSQNG---RREFVDV 83
gi 124444750   23 T---TKItNIEPIRLQKRRIVLGVFLSVITSFLFTLACSWSKKLVRKFFFKESQLEKATHMW--ITNNDN---SNNISKL 94
gi 74999922    41 SHkfDYPvYITPICRRLYLEKVYLIFQIFTLGIISIICHWFPNFYRWMNFKASTISECDSFL--VITKES---YYSVVNR 115
gi 74997157    23 NDp-LEIdYMRGYQTTTLSNILHYGLIILSAGLLLLVYHWVPRWGIKMRFKECKLNDANYVY--VKAKDK---KYELSQV 96
gi 74996861    44 GDdmLLVdKMVGYQSISSRELIYWLSILFSCGGILLIFYWFESFYINTRFKKSSISSANHVL--VYSKDS---RTEFCKV 118
gi 268537294    6 gD--HTL-TLFAYRTGPLKTVLFYALTFLTLGIFRLILHWKQKWNVKVRMVPCTFEAAEYVF--IVDNHN---VTELQPV 77
gi 170587426   14 DD--ENL-YLWGYKTNRIKMVLTWIVTVLTLGTFRLLLYWYPKWWVKCTASECSLSTADCLL--IRDAHM---DVAFRPV 85
gi 300706870    9 SD--SFI-EIEGRRKTIL-YNFYNFFCIITFGILYIICKNFPRVRIVLTTKQCDLKSADKAV--ITNKFK---KHELVDI 79
gi 169806312    1 mddkiTI-QFVGKRKIP--IMHRYLFTICTLGIYYVICKISKRMKIWLTYTSSTLYNATHIL--IIDQFR---NSKLYAI 72
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 74755755   108 QT-----EAIGEGSLEPSPQSqaedgrsqaavgavpegawkdtaqlhkseeAKRVLRYYLFQ 164
gi 74697535    84 LA-----YSTEEIPSLRRYSLegkarvvds------------lfsrliydvVSRRFVVPPEQ 128
gi 124444750   95 VKkq--nQVYFINRKLKYIYDsamntf-------------------kaleyDLKTKRELLKS 135
gi 74999922   116 NKffslnKNFSNDELNLLRFLnilpsqykfsdl-------kgqknsnnnisNSHRTSIINSS 170
gi 74997157    97 KH-----VLIGKKDLEFSESEkkdkyiefkft---------rlfynvekdlFIRPISNTDYH 144
gi 74996861   119 NYlveenEKYIIYRFSRFFFNeklqeyek--------------tklinqyeKIDFLRLVENG 166
gi 268537294   78 LR-----KT-----ETMIPTEnge-------------------------mrKVPELRWFLYR 104
gi 170587426   86 LC-----MISDSVMQMGFPITgfq-------------------------mtDVSTLRYFTFK 117
gi 300706870   80 LV-----YKCTKSQLMSRFVFngyvrvidt------------vyarliydvGFEKFVVYSYK 124
gi 169806312   73 KH-----ITLNPNHQYQLANSiilkc---------------------ffntKSNSIKILDtp 108
Citing CDD
Marchler-Bauer A et al. (2013), "CDD: conserved domains and protein three-dimensional structure.", Nucleic Acids Res. 41(D1):D384-52.
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