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pfam12356: DUF3643 
Protein of unknown function (DUF3643)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 217 and 4852 amino acids in length. There is a conserved TLA sequence motif.
Statistics
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PSSM-Id: 257002
View PSSM: pfam12356
Aligned: 5 rows
Threshold Bit Score: 229.876
Threshold Setting Gi: 82270770
Created: 29-Mar-2013
Updated: 4-Apr-2013
Structure
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Aligned Rows:
pfam12356 is a member of the superfamily cl13752.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104079 3462 RVAaMKRSGRMNYMCP----NSSTVEYGLLMPSPSHLHCVAAILWHSYELLVEYDLPALLDQELFELLFNWSMSLPCNMV 3537
gi 82270770   817 QVAsHKMSSPLGYAGPgaytSASLREFGLLMPSPSHLHCVAAILWHSYELPVNYDLHSLLNRDLFELLYSWSMSLPCNTA 896
gi 260831154 3439 arvaLRRHSCLSFRGSm--aTLSSVEQVLSTPSPAHIHCVAAIVWASYELPVQYNLLDILSQDFLSSIYEWSMVLDLGSP 3516
gi 194740932 3548 WVMqLHDNYSKQARCN--------------NPQSGFVKVIASILWRVHAQQQLPELPLLISSSLFETCFEWVSNLEHDEP 3613
gi 195388742 1509 WIMqLHDTYSKQARCN--------------NPQSGFVKVIASILWQVQRQQQVPDLPQLITPAFFETCYRWIAELEHDEP 1574
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 313104079 3538 LKKAVDSLLCSMCHVHPNYFSLLMGWMGITPPPVQCh-----hRLSMTDDSKKQDlssSLTDDSKNAQ------------ 3600
gi 82270770   897 LKKAVDSLLCSLCYIHPSYFSLLMSWMGIISLSSSSrsqvqhhHLSITDDGKKQQ---NVTDDSKHAR------------ 961
gi 260831154 3517 LKKSVDSLICSVCHVNPRYFTMLLEWMGISLNMAAS-------SANSTDDNKDRNa--SISDDTKEAHqehfdspmpsip 3587
gi 194740932 3614 LKSSFDSLLCALCYIKPELFNQLLVKLGVKLEPPAR----------------------GQTDDSKVQSgsawfrr---ag 3668
gi 195388742 1575 LKSSFDALICALCYIKPELFNQLLVKLGVKLEQQPR----------------------GKTDDSKVQSgcawfrr---eg 1629
                         170       180
                  ....*....|....*....|..
gi 313104079 3601 ----APLALTESHLATLASSSQ 3618
gi 82270770   962 ----PPVNLSESQLSTLAAASQ 979
gi 260831154 3588 vqdfSHLVLDESHLNTLAFACQ 3609
gi 194740932 3669 genlTVLLQRPTFLKTLALACQ 3690
gi 195388742 1630 tenlTQLLQYPAFLKTLALACQ 1651
Citing CDD
Marchler-Bauer A et al. (2013), "CDD: conserved domains and protein three-dimensional structure.", Nucleic Acids Res. 41(D1):D384-52.
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