Conserved Protein Domain Family
NPDC1
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pfam06809: NPDC1 
Neural proliferation differentiation control-1 protein (NPDC1)
This family consists of several neural proliferation differentiation control-1 (NPDC1) proteins. NPDC1 plays a role in the control of neural cell proliferation and differentiation. It has been suggested that NPDC1 may be involved in the development of several secretion glands. This family also contains the C-terminal region of the C. elegans protein CAB-1 which is known to interact with AEX-3.
Links
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Statistics
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PSSM-Id: 284276
Aligned: 2 rows
Threshold Bit Score: 472.757
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EDL08242   1 MATPVPPPSPRHLRLLRLLLSGLILGAALNGATARRPDATTCPGSLDCALKRRAKCPPGAHACGPCLQSFQEDQRGFCVP 80 
Q9NQX5     1 MATPLPPPSPRHLRLLRLLLSGLVLGAALRGAAAGHPDVAACPGSLDCALKRRARCPPGAHACGPCLQPFQEDQQGLCVP 80  human

EDL08242  81 RkhlssdpsvvtmetkivklwMGPSISGG-----------CLLQELAlkEKEAGHSrltAQPLLEAAQKLLEPaATLGFS 149
Q9NQX5    81 R--------------------MRRPPGGGrpqprledeidFLAQELA--RKESGHS---TPPLPKDRQRLPEP-ATLGFS 134 human

EDL08242 150 QWGQRLEPGLPSTHGTSSPIPHTSLSSRASSGPVQMSPLEPQGRHGNGLTLVLILAFCLASSAALAVAALCWCRLQREIR 229
Q9NQX5   135 ARGQGLELGLPSTPGTPTPTPHTSLGSPVSSDPVHMSPLEPRGGQGDGLALVLILAFCVAGAAALSVASLCWCRLQREIR 214 human

EDL08242 230 LTQKADYaATAKGPTSPSTPRISPGDQRLAHSAEMYHYQHQRQQMLCLERHKEPPKELESASSDEENEDGDFTVYECPGL 309
Q9NQX5   215 LTQKADY-ATAKAPGSPAAPRISPGDQRLAQSAEMYHYQHQRQQMLCLERHKEPPKELDTASSDEENEDGDFTVYECPGL 293 human

EDL08242 310 APTGEMEVRNPLFDHSTLSAPVPGPHSLPPLQ 341
Q9NQX5   294 APTGEMEVRNPLFDHAALSAPLPAPSSPPALP 325 human
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