6A4I


Conserved Protein Domain Family
Trp_dioxygenase

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pfam03301: Trp_dioxygenase 
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Tryptophan 2,3-dioxygenase
Statistics
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PSSM-Id: 281317
Aligned: 6 rows
Threshold Bit Score: 350.406
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6A4I_A  29 DKSQTGVNRASKG-GLIYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRD 107
O77457  11 DSVQGGHHLGSEA-GMLYGEYLMLDKVLSAQRMLSVEGKKPVHDEHLFIVTHQAYELWFKQIIFELDSIRDLFSTEHIEE 89  African malaria mosquito
P21643  26 DGAQTGVNRASKG-GLIYGDYLQLEKILNAQELQSEIKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRD 104 Norway rat
Q9X8R3   1 MSHDAPNLDFEGS--TPYEDYVKADVLTHLQHTLSD-----DPGEMVFLVTTQVMELWFTVIVHEWETAARALREDRTPV 73  Streptomyces coelicolor
Q9RYH4  16 HSAEQAHRDFSRS--LSYGDYLHLDELRSAHQPITD-----AHDEHLFIAIHHVSEVWLSLIVRELQAAMRLLDAGITDA 88  Deinococcus radiodurans
Q09474  22 EECQQGVNKVEMGfGQTYSEYLQLDKILTAQRLKSEADGQRVDDEHLFIVIHQAHELWFKQIIFDLDNVRKLLNNTIVDE 101 Caenorhabditis elegans
6A4I_A 108 ERnMLKVVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQNMRVPYNRRhYRDNF 187
O77457  90 SR-TLEILKRLNRIVMILKLLVDQVPILETMTPLDFMDFRDYLSPASGFQSLQFRLLENKLGVKSEHRVKYNQK-YTEVF 167 African malaria mosquito
P21643 105 ERnMLKVMTRMHRVVVIFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRKhYRDNF 184 Norway rat
Q9X8R3  74 AT------DALKRSVRELEALNASWTPLAGLTPAQFNSYRSALGEGSGFQSAMYRRLEFLLGDKSAS------------- 134 Streptomyces coelicolor
Q9RYH4  89 PL------KMLTRVVRAQEQLTAAWDVLKTMTPADYLQFRGAFGQASGFQSQNYRMVEFLLGNRNS-----------T-- 149 Deinococcus radiodurans
Q09474 102 TK-TLKIVSGLDRMTKILSLLTEQITLLDTMSPLDFVDFRKYLTPASGFQSLQFRVLENKLGVRQERRIKYNAQhYKNVF 180 Caenorhabditis elegans
6A4I_A 188 KGEEN--ELLLKSEQEKTLLELVEAWLERTPGLEPHGFN--FWGKLEKNITRGLEEEFIRIQAKEESEEKEEQV-AEFQK 262
O77457 168 ASDPGaiERIGTTETEPSLADLVQKWLERTPGLEQDGFN--FWGKFQESVEQLLAEQEASAMSEEHENVREYRL-MDIDK 244 African malaria mosquito
P21643 185 EGDYN--ELLLKSEQEQTLLQLVEAWLERTPGLEPHGFN--FWGKFEKNILKGLEEEFLKIQAKKDSEEKEEQM-AEFRK 259 Norway rat
Q9X8R3 135 ---------MLVPHRGAPRVHAELEKALHEP-----------------SLYDEVVRLLARRGYDIPDAVLQRDLtRKYEA 188 Streptomyces coelicolor
Q9RYH4 150 ---------LLRPHEHRADLHRPLAAALHAP-----------------SVYDLTLRLLAARGLPVPAEVLQRDYaQPYQT 203 Deinococcus radiodurans
Q09474 181 NDTDL--KTLNVTEEEKSLLTLIESWLERTPGLKSTSEDegFWIKYEKSVNKYLADLAKQAADPSNTEEIAKQLtAEYHK 258 Caenorhabditis elegans
6A4I_A 263 QKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDSLMTKWRYNHVCMVHRMLGS- 341
O77457 245 RREVYKSIFDAQVHDALVARGERRFTHKALQGAIMITFYRDEPRFSQPHQLLMLLMDIDSLITKWRYNHVIMVQRMIGSq 324 African malaria mosquito
P21643 260 QKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMLGS- 338 Norway rat
Q9X8R3 189 APEVEAAWTA---------------------------VYSGDQNG-ELARLGEALTDVAELVWRWRNDHLVATRRAMGS- 239 Streptomyces coelicolor
Q9RYH4 204 NEAVLASWLS---------------------------VYCDTETYWDLYELAEKLVDVEDNFRRWRFNHLTTVERTIGF- 255 Deinococcus radiodurans
Q09474 259 TADAFQSILDPRQHEQHIRNGNRLLSHDATKGAMMIYFYRDMPRFSQPYQILTFLMDIDSLFTKWRYNHVLLVQRMLGA- 337 Caenorhabditis elegans
6A4I_A 342 KAGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYL 375
O77457 325 QLGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFL 358 African malaria mosquito
P21643 339 KAGTGGSSGYYYLRSTVSDRYKVFVDLFNLSSYL 372 Norway rat
Q9X8R3 240 KTGTGGSAGVAWLEK--RARNNVFPELWTARSYV 271 Streptomyces coelicolor
Q9RYH4 256 KRGSGGTSGVGYLRG--ALDVVLFPELWDVRTQL 287 Deinococcus radiodurans
Q09474 338 KQGTGGSSGYMYLRSTVSDRYKVFLDLFNLSTWL 371 Caenorhabditis elegans
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