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pfam01048: PNP_UDP_1 
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Phosphorylase superfamily
Members of this family include: purine nucleoside phosphorylase (PNP) Uridine phosphorylase (UdRPase) 5'-methylthioadenosine phosphorylase (MTA phosphorylase)
Statistics
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PSSM-Id: 250322
View PSSM: pfam01048
Aligned: 159 rows
Threshold Bit Score: 71.615
Threshold Setting Gi: 81759741
Created: 28-Mar-2013
Updated: 4-Apr-2013
Structure
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Program:
Drawing:
Aligned Rows:

pfam01048 is a member of the superfamily cl00303.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3BSF_B        15 TIVFIVAMQKEAQPLINRlrlvE--EVNTPFPKEvt---wiMFKGMYKDLNINIVCPGkdstlgvesVGTVPASlvTYAS 89
gi 81437139    2 KLGVIAAMDLELQKLLEY----------FPPQRKiqlakntFYIYEQKTSQVIMVCAG---------QGKTNAT--LYSQ 60
gi 81613824    2 KFGIIGPSEDEIMPFIEE-------MTNKEITNLam---ltFHSGKYENVEVVALYCG---------VCKVNAA--IATQ 60
gi 81609892   27 NVLIVTAMDSELEEINKLm--sN--KEEIVLKEYgln--kkIVKGKLSNRNVMAIVCG---------VGKVNAG--VWTS 89
gi 81572143    4 TIGVVVAMEKEFRLLPDI-------LENKEEIRDav---frAVVGIVGGHRVIYALSG---------IGKVAAA--VCAG 62
gi 221272130   2 IIGVIGAMEQEVMLLSKQ-------LAKLNIWQQar---cnIYSGWLHGKKVVLVQSG---------IGKVSAA--LGCT 60
gi 81741653    9 KIGIIGALSREIQIIISK-------LKNYSIKKDki---ftLHMGTINFSKIAIIKSG---------IGKVLSS--INTL 67
gi 118497093   3 KIAILGAMEIEIQPILDK----LnsYETIEYANNk------YYLANYQDKELVIAYSK---------IGKVFSSl-TATI 62
gi 157961390  41 TIAILGAMDAEIEKLL------P--EIKQRQTHTiak--ntYYTGVIQGKPVVVARSG---------VGKVNAA--ITTY 99
gi 123446857   3 TIAFLCALKEEEEAISKKfqetC--EAKVEKISSytf--kvFTKGNV---KIIITICG---------CGKVNAS--ITAT 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3BSF_B        90 ILAI--QPDLIINAGTAGGFk---AKGACISDVYVVSTVAFHDRRIP---VPVLD----IYGV-GMRNTFPTPNLIKE-- 154
gi 81437139   61 ILIDsfQIEQLINIGICGCL----NEKLQLFEMVLGEEYCHYDIRER---QSI------NKFP-YQLYYKGDKGMLAElq 126
gi 81613824   61 ILIDkfDITHIIVTGVAGAI----DKVLKIGDTVISTEIAYHDVDEGi-lTEY------HPWM-ESVYFKTDSTLLELsr 128
gi 81609892   90 YILSkyNISHVINYGVAGGVisdkYKDIKVGDIVVSSEIAYHDVDLT---KFGYKm--gQLMG-LPQKFIANKNLVNKak 163
gi 81572143   63 ELICryRPDYLINIGVSGGL----GRNVAIHDTVVSTAVCYHDVSCGadiAWG------QVQG-FPLYYPVSEDLLALfr 131
gi 221272130  61 LLLTnfEATLVINIGSAGGL----SPALAVGDIIVSEEVQYHDVNVT---AFGYDkgqmAQYP-LLFPA--SPSLVALtk 130
gi 81741653   68 HLIKlfNPDLIINIGISGSL----RKELLIGDIIISKKICYHDVDLT---YFGYKi--gQIPK-NPKYYYSPYPLVKIle 137
gi 118497093  63 -MIErfGVEALLFSGVAGGL----Q-DLKVGDMIAATATVQHDVDIT---AFGYPy--gKIPI-SEVEIKTSAKLLKQaq 130
gi 157961390 100 VLINhfDVNSIIFTGIAGAA----GPDLNVADVVISTALVQHDVDLT---AFGAPk--gLLDGyDDRLFYADKKLQALal 170
gi 123446857  65 LTIVtyKPDYVINCGVAGGF----DKQQKILDWVISTNFVYHDVDIE---CLGFKp--gQLLG-EPTEFDASAKLVNLik 134
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3BSF_B       155 ---------LNLKVgrlSTGDSMDMSPh--DEES---ITANDA--TVkDMEGAAVAYVADIFKVPTILIKGVTD----IV 214
gi 81437139  127 h------ldEKIKCvrfGTGEGFVCDTt--EKRN---LIEQFSidCV-DMESAAIAQCCFLNDCAFVSIRIICD----RA 190
gi 81613824  129 eviennqftQNIYFgkvVTGEAFISES---GRTE---IISKYNplCV-DMETASIAHVCYANTIPFLAVRSITD-----T 196
gi 81609892  164 eavklkvrgSNAYSgliLTGDQFIDPIyikKIIR---DFKDVI--AV-EMEGAAIGHVAHMLNVPFVVIRSISD----IV 233
gi 81572143  132 s------lpVPVREgvvCCGDRFLSSSe--EQDFvrrTFPDAV--AV-DMESAALAQVAYIYRVPFIAVRIISDiageGR 200
gi 221272130 131 qlt--ehtnINVVCgqiISGDIFINGGq--ELYK---LKRRFPqaIAvDMEVTAIAQICYLFAVPFVGIRVITD-----I 198
gi 81741653  138 nis--dligLNFKSgliISGDSFIHCKeknNLLKikkFFPHAY--AV-DMESSSIAQVCNIFCIPFISIRSISD----CI 208
gi 118497093 131 nva--nelgLNLHTgviATGDQFVHCAe--RKDF---VIKEFDakAI-EMEGASVNLICNEMGVPSLILRSISDtadgNA 202
gi 157961390 171 naavesvgkARVHTgiiATGDQFIADKa--VVSM---LLKEFSaiAV-EMEGAAVAQVTDMFDIPLVVIRTISDkadgSA 244
gi 123446857 135 elekenkfpMNIFYgtiASGDQFVSTDd--QVQRiqkKFPSVI--CV-EMEGCAIAHACSKFNVPVLAIRALSDiavsEH 209
                        250       260
                 ....*....|....*....|....*....
3BSF_B       215 DGNR--PTSEEFLENLAAVTAKLDESLTK 241
gi 81437139  191 DANAv-KVTEDTQTQAMEKVFELVCAYIN 218
gi 81613824  197 EEASgiEVFEDNCVSASYHSIHFVKKLLE 225
gi 81609892  234 NKEEneVEYSKFLKLASFNSAKVVQEILR 262
gi 81572143  201 DNF---AEYMDFWRKASPATFSILERVFD 226
gi 221272130 199 ADSVshKSFKDNLITVVSHLSLLVSDIIQ 227
gi 81741653  209 YEENk-IKFKLNSYLAIKNFSNITLKFIK 236
gi 118497093 203 P-----ENFDEFAKMAAKRSANFIMQILS 226
gi 157961390 245 h-----LVYEEAKQVTADNSVAITLNMLS 268
gi 123446857 210 DNS---VDFTRTCVVASERAANLAYLIVE 235
Citing CDD
Marchler-Bauer A et al. (2013), "CDD: conserved domains and protein three-dimensional structure.", Nucleic Acids Res. 41(D1):D384-52.
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