3ECH,1S3J,2NYX,5X80,1Z9C,2FXA,3BPX,3Q5F


Conserved Protein Domain Family
MarR
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pfam01047: MarR 
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MarR family
The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.
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Statistics
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PSSM-Id: 426012
Aligned: 35 rows
Threshold Bit Score: 57.5573
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3ECH_B  35 LTPPDVHVLKLIDEQRGLNLQ---DLGRQMCRDKALITRKIRELEGRNLVRRERNPSDQRSF 93  Pseudomonas aeruginosa
O31443  35 FSLTETRILFEIYNTPNCTAK---ALQDKLGLDRGYVSRIVKQFEKEDLIYKQRSKDDARHH 93  Bacillus subtilis subsp. subtilis str. 168
O34692  47 WTLTQLHIVSCIHTSQNVNNS---FLASRLHISKAAVSKAVHALLKHNIITVTKKPGNKKEI 105 Bacillus subtilis subsp. subtilis str. 168
Q796S4  49 LTMTEIHVLSCVGDNEPINVT---SIAEKMNTTKATVSRISTKLLGAGFLHRTQLSDNKKEV 107 Bacillus subtilis subsp. subtilis str. 168
P40762  45 KNMTSIHVIDCIGQHEPINNA---GIARKMNLSKANVTKISTKLIKEEFINSYQLTDNKKEV 103 Bacillus subtilis subsp. subtilis str. 168
O34949  41 FNPTEFAVLELLYTRGPQKLQ---QIGSRLLLVSGNVTYVIDKLERNGFLVREQDPKDKRSV 99  Bacillus subtilis subsp. subtilis str. 168
O31672  32 LNPTEFAVLELLYHKGDQPLQ---QIGDKILLASGSITYVVDKLEQKELLIRKASPTDRRVT 90  Bacillus subtilis subsp. subtilis str. 168
2FXA_C  46 LNINEHHILWIAYQLNGASIS---EIAKFGVXHVSTAFNFSKKLEERGYLRFSKRLNDKRNT 104 Bacillus subtilis
P0ACR9  53 INETLFMALITLESQENHSIQp-sELSCALGSSRTNATRIADELEKRGWIERRESDNDRRCL 113 Escherichia coli K-12
P42195  52 LSAREFDILATLRRRGAPYAIspsQIVNALMINNSTLTSRLDRLEQAGWLRRMPIEGDRRSV 113 Dickeya dadantii 3937
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