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PH domain
PH stands for pleckstrin homology.
Statistics
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PSSM-Id: 249648
View PSSM: pfam00169
Aligned: 133 rows
Threshold Bit Score: 31.6697
Threshold Setting Gi: 76363537
Created: 28-Mar-2013
Updated: 4-Apr-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam00169 is a member of the superfamily cl17171.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3KRX_A       558 CIMHGYMSKMGn----PFLTQWQRRYFYLFP--NRLEWRGEG-----EAPQSLLTMEEI-QSVEETQI---------KER 616
gi 67477442  457 PEMEGFLYLKS-----DGRKSWKKHYFVLRP--SGLYYAPKSkkpttKDLTCLMNLHSN-QVYTGIGWekky-ksptPWC 527
gi 6016154   229 PEIQGFLQLRGsg-rgSGRKLWKRFFCFLRR--SGLYYSTKGtskdpRHLQYVADVNES-NVYVVTQGrkl---ygmPTD 301
3HK0_B       132 PEIQGFLHVKE-----LGKKSWKKLYVCLRR--SGLYCSTKGtsaapRHLQLLADLEDS-NIFSLIAGrkq---ynaPTD 200
gi 730742    310 PEKSGWLYMKTqv-gkPTREIWVRRWCFLKNavFGMFLLSPSktyveETDKFGVFLTNV-RYDPEED-----------RK 376
gi 731730    309 KGLSGWLYMKTtvghdPKRVVWVRRWCFLQN--NVFGVFSLSpsktyVEETDKFGILWI-TVEYLPKE---------PRN 376
gi 73619423  239 VKMSGNLNIRT------KLIRSTRYWCVLKN--HLFSMYTSSte--lYFPVLTIDLREVqKIETQKHTln------gSAT 302
gi 74962052  893 VEYRGFLYLFDer-spNGEAAWDRYWAMLHR--GIIFFWKNPi----DEKNQKVPLSQI-DLTKCTNQsveetrngrDHE 964
gi 586539    216 QVCSGILYTKVkkkklFNRAKWQKFNVELTNtsFNLYSFKTG------KLKKSIKLDKIiDCIELDNNsk-----mkNDD 284
gi 2828204   635 NVKDGSLLLRRpk-tlTGNSTWRVRYGILRD--DVLQLFDKN------QLTETIKLRQS-SIELIPNLped----rfGTR 700
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
3KRX_A       617 KCLLLKIRGGk------------QFILQCDSDPELVQWKKELRDAYR 651
gi 67477442  528 ISIKLTALQMkrs--------qfIKYICAEDEMTFKKWLVALRIAKN 566
gi 6016154   302 FGFCVKPNKLrng-------hkgLHIFCSEDEQSRTCWLAAFRLFKY 341
3HK0_B       201 HGLCIKPNKVrne-------tkeLRLLCAEDEQTRTSWMTAFRLLKY 240
gi 730742    377 FCFEVKIFGNkvteahdnmskdiTLVFQTSNYLDLKSWLIAFEATKK 423
gi 731730    377 FCFKLRIQNPncktee--entyiDIILQAESIDELKSWINTLTSHKR 421
gi 73619423  303 KTFKLYTDES-------------TFKFNADSEFSAKSWVNALKKEQF 336
gi 74962052  965 FHIELLIDQTpsll------ekrRVVLAAESSDHLASWLNAINDTLF 1005
gi 586539    285 TNFALITFDE-------------RLSFKAANDQDMVDWIINFKSGIL 318
gi 2828204   701 NGFLITEHKKsgls------tstKYYICTETSKERELWLSAFSDYID 741
Citing CDD
Marchler-Bauer A et al. (2013), "CDD: conserved domains and protein three-dimensional structure.", Nucleic Acids Res. 41(D1):D384-52.
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