Conserved Protein Domain Family
Fibrinogen_C

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pfam00147: Fibrinogen_C 
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Fibrinogen beta and gamma chains, C-terminal globular domain
Statistics
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PSSM-Id: 278572
View PSSM: pfam00147
Aligned: 5 rows
Threshold Bit Score: 355.677
Threshold Setting Gi: 120140
Created: 11-Jun-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam00147 is a member of the superfamily cl00085.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1M1J_E        212 SGRECEDIYRKGGETSEMYIIQPDPFt-TPYRVYCDMETDNGGWTLIQNRQDGSVNFGRAWDEYKRGFGNIAKsggkkyc 290
gi 120140     173 TGRDCQDVANKGAKESGLYFIRPLKA--KQFLVYCEIDGSGNGWTVFQKRLDGSLDFKKNWIQYKEGFGHLSPtgt---- 246
gi 120159     202 IYKDCSDHYVLGRRSSGAYRVTPDHRn-SSFEVYCDMETMGGGWTVLQARLDGSTNFTREWKDYKAGFGNLER------- 273
gi 281185495 1980 FPKDCSQAMLNGDTTSGLYTIYLNGDkaEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRR-------- 2051
gi 290457668 4071 FPRDCGEEMQNGAGASRTSTIFLNGNreRPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNIS-------- 4142
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1M1J_E        291 dtpGEYWLGNDKISQLTKIG--PTKVLIEMEDWNGDKVSALYGGFTIHNEGNKYQLSVSNYKG-NAGNALMegasqlyGE 367
gi 120140     247 -gnTEFWLGNEKIHLISTQSsiPYVLRIQLEDWNGRTSTADYASFKVTGENDKYRLTYAYFIGgDAGDAFDgydfgddSS 325
gi 120159     274 ----EFWLGNDKIHLLTKSK--EMILRIDLEDFNGLTLYALYDQFYVANEFLKYRLHIGNYNG-TAGDALR--------F 338
gi 281185495 2052 ---EEFWLGLDNLNKITAQG--QYELRVDLRDH-GETAFAVYDKFSVGDAKTRYKLKVEGYSG---------------TA 2110
gi 290457668 4143 ---GEFWLGNEALHSLTQAG--DYSMRVDLRAG-DEAVFAQYDSFHVDSAAEYYRLHLEGYHG---------------TA 4201
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1M1J_E        368 NRTMTIHNGMYFSTYDRDNDgwlttDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGTYSWDmakhgtdDGIVWMNWKGS 447
gi 120140     326 DKFFTSHNGMQFSTWDSDND-----KYDGNCAEQVGIGWWMNKCHAGHLNGVYYQGGTYSKTstpngydNGIIWATWKSR 400
gi 120159     339 SR-HYNHDLRFFTTPDRDNDr----YPSGNCGLYYSSGWWFDSCLSANLNGKYYHQKYKGVR-------NGIFWGTWPGI 406
gi 281185495 2111 GDSMAYHNGRSFSTFDKDTD-----SAITNCALSYKGAFWYRNCHRVNLMG--RYGDNNHSQ--------GVNWFHWKGH 2175
gi 290457668 4202 GDSMSYHSGSVFSARDRDPN-----SLLISCAVSYRGAWWYRNCHYANLNG--LYGSTVDHQ--------GVSWYHWKGF 4266
                         250       260
                  ....*....|....*....|..
1M1J_E        448 --------WYSMKKMSMKIKPY 461
gi 120140     401 --------WYSMKKTTMKIIPL 414
gi 120159     407 nqaqpggyKSSFKQAKMMIRPK 428
gi 281185495 2176 --------EHSIQFAEMKLRPS 2189
gi 290457668 4267 --------EFSVPFTEMKLRPR 4280
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