Conserved Protein Domain Family
ABC_tran

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pfam00005: ABC_tran 
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ABC transporter
ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Statistics
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PSSM-Id: 278435
View PSSM: pfam00005
Aligned: 55 rows
Threshold Bit Score: 95.025
Threshold Setting Gi: 127359
Created: 10-Jun-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam00005 is a member of the superfamily cl21455.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JJ7_A         33 LQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQP--TGGQLlldgkp-----------------------------l 81
gi 398987      22 LNSLNLSIKPGEIHAIMGKNGSGKSTLAKVIAGHPSYkiTNGQIlfenqd------------------------------ 71
gi 26393280   709 LDNVTVGLSLSSRVAILGPNGAGKSTLIKVLIGEVIP--QEGKVfkhpnlrvgyvaqhafhhldqhlektpsqyiqwrya 786
gi 742871313   21 FSDVSFDLWPGEVLGIVGESGSGKTTLLKSISARLTP--QQGEIhyenrsly-------------------------ams 73
gi 768816517  411 YEHLNFGVDMDSRIALVGPNGVGKSTLLKIMTGELTP--QSGRVs----------------------------------- 453
gi 553675940   40 IDDLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQEQP--DSGTItl---------------------------------- 83
gi 745776037   18 LNDVSLSLPTGKITALIGPNGCGKSTLLNCFSRLLMP--QSGTVflgdnp-----------------------------i 66
gi 12724192    37 LKDITWKVNPGENWVILGLNGSGKSSLLKLILAEEWK--TSGEItvlntq-----------------------------f 85
gi 207341112  176 LKPMDGCLNPGELLVVLGRPGSGCTTLLKSISSNTHGfdlgadtkis----------------------------ysgys 227
gi 323356004  347 LNEISGIVKPGQILAIMGGSGAGKTTLLDILAMKRKTghVSGSIkvngi------------------------------- 395
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JJ7_A         82 pqyehRYLHRQVAAVGQE--PQVFGRS--LQENIAYGLTqk------------------------------------ptM 121
gi 398987      72 vteiePEDRSHLGIFLAFqyPVEIPGVt-NADFLR--------------------------------------------I 106
gi 26393280   787 ggqdrEVSEKESRKLTEEdrAQLQRDItvNGERRRVEALigrqklkksfqyeikwfgkphkyntwvsreillengfqkfV 866
gi 742871313   74 eadrrRLLRTEWGVVHQHplDGLRRQVs-AGGNIGER------------------------------------------L 110
gi 768816517  454 -----RHTHVKLGVYSQHsqDQLDLTKs-ALE-----------------------------------------------F 480
gi 553675940   84 ------gETVKLASVDQFr-DSMDNSKt-VWEEVSGGLD----------------------------------------I 115
gi 745776037   67 nmlssRQLARRLSLLPQH---HLTPEGitVQELVSYGRNpw------------------------------------lsL 107
gi 12724192    86 gngeiPKLRKRISVVGSFiaERFQPNI--KAENLVYTGKf--------------------------------------nS 125
gi 207341112  228 gddikKHFRGEVVYNAEA--DVHLPHLt-VFETLVTIAR----------------------------------------L 264
gi 323356004  396 -smdrKSFSKIIGFVDQD--DFLLPTLt-VFETVLNSALlr-------------------------------------lP 434
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
1JJ7_A        122 EEITAAAVKSG--------AHSFISGLPQGY--DTEVde-agSQLSGGQRQAVALARALIRKPCVLILDDATS 183
gi 398987     107 AYNAKRAFDNKeeldplsfFSFIENKISNIDlnSTFLsrnvnEGFSGGEKKKNEILQMSLLNSKLAILDETDS 179
gi 26393280   867 QAFDDMESSREglgfreliPEDIRAHFEDVGlpGDIAdyspiSSLSGGQKVKVVIAACLWNNPQLLVLDEPTN 939
gi 742871313  111 MATGARHYGDI--------RATAQKWLEEVEipANRIdd-lpTTFSGGMQQRLQIARNLVTHPKLVFMDEPTG 174
gi 768816517  481 VRDKYSNISQD--------FQFWRGQLGRYGltGEGQtv-qmATLSEGQRSRVVFALLALEQPNVLLLDEPTN 544
gi 553675940  116 MKIGNTEMPSR--------AYVGRFNFKGVDqgKRV------GELSGGERGRLHLAKLLQVGGNMLLLDEPTN 174
gi 745776037  108 WGRLSAEDNAR--------VNVAMNQTRINHlaVRRL-----TELSGGQRQRAFLAMVLAQNTPVVLLDEPTT 167
gi 12724192   126 SMLYKPYTDQE--------LDEARQLLRQMGa-KSLIgr-nyASLSQGEKQVLLIARSLILKPELLILDEATN 188
gi 207341112  265 KTPQNRIKGVDresyanhlAEVAMATYGLSHtrNTKVgndivRGVSGGERKRVSIAEVSICGSKFQCWDNATR 337
gi 323356004  435 KALSFEAKKAR--------VYKVLEELRIIDikDRIIgnefdRGISGGEKRRVSIACELVTSPLVLFLDEPTS 499
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