2ZF5_O 3 KFVLSLDEGTTSARAIIFD-RESNIHGIGQYEFPQHYPRPGWVEHNPEEIWDAQLRAIKDAIQSAR---IE---PNQ-IA 74 Thermococ... CAC36363 9 PFIAAIDQGTTSSRCIVFD-RDGRIVSVDQKEHEQIFPKPGWVEHDATEIWTNVQEVVAGAVEKAG---IT---RDD-IK 80 Streptomy... CAC25769 8 AYVAAIDQGTTSTRCIFID-AQGKVVSSASKEHRQIFPQQGWVEHDPEEIWDNIRSVVSQAMVSID---IT---PHE-VA 79 Corynebac... AAF27123 6 GFIGSIDQGTTSTRFIIYD-HDARPVASHQVEFTQFYPEAGWVEHDPMEILESVKVCIAKALDKAT---ADghnVDGgLK 81 thale cress FlyBase:CG18374-PA 18 PFVGAIDEGTTSARFIIFRaGTDEIVCFHQIEVESIFQKEGWCEQDPMAIVNTVNECITGACKKLV---AVggkVEE-II 93 fruit fly FlyBase:CG7995-PA 31 GLVGVIDEGTKTIGFSIYTtPDFKEIAAHRVELSVITPQDGWYEQDPLEMMASINKCAEEAIKQLP---EQgfsASD-IV 106 fruit fly AAF61320 2 KYVGSIDQGTTSTRFIIFD-ERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLR---QKdasFRK-IE 76 Trypanoso... Q21944 2 VLLAAIDQGTSSSRFLVFEaDTGELVTSHQIEVRQLFPHGGWVEMDPMELYDTVVSCISKTIEKLE---NLgisADE-IK 77 Caenorhab... WP_003899643 15 DFIAAIDQGTTSTRCMIFD-HHGAEVARHQLEHEQILPRAGWVEHNPVEIWERTASVLISVLNATN---LS---PKD-IA 86 Mycobacte... XP_009232964 11 PLVGAVDQGTSSTRFLVFNsKTAELLSHHQVEIKQEFPREGWVEQDPKEILHSVYECIEKTCEKLGqlnID---ISN-IK 86 Sumatran ...
2ZF5_O 75 AIGVTNQRETTLVWDKD-GKPLYNAIVWQCRRTAEMVEEIKRE-YG-----T--MIKEKTGLVPDAYFSASKLKWLLDNV 145 Thermococ... CAC36363 81 AIGITNQRETTLVWDKNtGEPVHNAIVWQDTRTDALCKELGRNvGQ-----D--RFRRETGLPLASYFAGPKARWLLDNV 153 Streptomy... CAC25769 80 SLGVTNQRETTVVWDKHtGEPVYNAIVWQDTRTSDICLEIAGEeGQ-----E--KWLDRTGLLINSYPSGPKIKWILDNV 152 Corynebac... AAF27123 82 AIGLTDQRETTVVWSKStGLPLHKAIVWMDARTSSICRRLEKElSGg---rS--HFVESCGLPISTYFSAMKLLWLMENV 156 thale cress FlyBase:CG18374-PA 94 TIGITNQRESTVVWDRNsGQPLVNAIIWLDNRTTSTVEELLETiPNnarniN--YLRPLCGLPLSPYFSGVKLRWLRDNV 171 fruit fly FlyBase:CG7995-PA 107 TVGITNQRETTIVWDAVtGKPLYNALLWKDIRTSTTVEQIVAKvQDp----N--HFRSSTGLPISTYFSALKIRWLRDNV 180 fruit fly AAF61320 77 AIGITNQRETTVAWDRVtKEPLCYAPVWNDLRTYDITKKVTAElGGgd--sM--FASKITGLPVSTYFAAFKMRWMLENV 152 Trypanoso... Q21944 78 SVGVANQRETSIVWDKEtGKPLYNAIVWLDTRTSSLADEAISRtASks--kD--EFRAKTGLPIHPYFSALKLKWLFQNV 153 Caenorhab... WP_003899643 87 ALGITNQRETTLVWNRHtGRPYYNAIVWQDTRTDRIASALDRDgRG-----N--LIRRKAGLPPATYFSGGKLQWILENV 159 Mycobacte... XP_009232964 87 AIGVSNQRETTVVWDKItGEPLYNAVVWLDLRTQSTVESLSKRiPG-----NnnFVKSKTGLPLSTYFSAVKLRWLLDNV 161 Sumatran ...
2ZF5_O 146 PGLREKAEKGEVMFGTVDTFLIYRLTG----------EHVTDYSNASRTMLFNIKKLDWDDELLELFDIPESVLPEVRES 215 Thermococ... CAC36363 154 DGLRERAEAGDLLFGTMDTWVIWNLTGgvn-----ggKHVTDVTNASRTMLMNLHTMAWDEKIAESIGVPMQMLPEIRSS 228 Streptomy... CAC25769 153 EGARERAEKGDLLFGTMDTWVLWNLTGgvrgddgddaIHVTDVTNASRTLLMDLRTQQWDPELCEALDIPMSMLPEIRPS 232 Corynebac... AAF27123 157 DDVKDAIKKGDAIFGTIDTWLIWNMTGgin-----ggLHVTDVTNASRTMLMNLKTLSWDQDTLKTLGIPAEILPKIVSN 231 thale cress FlyBase:CG18374-PA 172 PVVSQAMEKGTAMFGTIDTWLMYNLTGgkd-----cgVHKTDVTNASRTMLMNIETLQWDANLLKFFGLPKTILPEICSS 246 fruit fly FlyBase:CG7995-PA 181 PEVRQAIRERRCKAGTVDSWIVWNLTng--------aLHITDVTNASRTLLMNLETQAWDPVLLKTFGIREEMLPTIHSC 252 fruit fly AAF61320 153 PAVADACRRGTLCFGTIDTWLMYKLSGg--------kAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSN 224 Trypanoso... Q21944 154 PEVKKAYADGNLMFGTVDTWLIWKLTg----------AYVTDVSNASRTLLLDLHKRKWSTQLCEFFDLPIEILPEIRSS 223 Caenorhab... WP_003899643 160 DGVRAAAENGDALFGTPDTWVLWNLTGgpr-----ggVHVTDVTNASRTMLMDLETLDWDDELLSLFSIPRAMLPEIASS 234 Mycobacte... XP_009232964 162 RKVQKAVEEKRALFGTIDSWLIWSLTGgvn-----ggVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEILPNVRSS 236 Sumatran ...
2ZF5_O 216 --SEVYGYTKK-E------LLGAEIPVSGDAGDQQAALFGQAAFEAGMVKATYGTGSFILVNTDKMVLYSDN-LLTTIAW 285 Thermococ... CAC36363 229 --AEVYGEITG-Grl---gELLGGIPVASALGDQQAALFGQTCFSEGETKSTYGTGTFMVMNTGDKLINSYSgLLTTVGY 302 Streptomy... CAC25769 233 -----VGEFRS-Vrh---rGTLADVPITGVLGDQQAALFGQGGFHEGAAKNTYGTGLFLLMNTGTSLKISEHgLLSTIAY 303 Corynebac... AAF27123 232 --SEVIGEICK-G------WPIPGIKIAGCLGDQHAAMLGQACRK-GEAKSTYGTGAFILLNTGEVPIKSGHgLLTTLAY 301 thale cress FlyBase:CG18374-PA 247 --SEFYGSIAQ-G-------VLQGIGITSVLGDQQAALVGQQCLAKGQAKATYGTGCFLLYNTGPSIVHSTHgLLTTVGY 316 fruit fly FlyBase:CG7995-PA 253 --SEIFGKITS-Er-----sPLRGMTLSGIMGNQQASLLGQMCVKPGQTKNTYRSGCFLLCNTGDKPVFSRHgLLTTVAY 324 fruit fly AAF61320 225 --SELFGYVET-DecgvaaALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHgLLSTVGF 301 Trypanoso... Q21944 224 --AEVYGHFDK-G-------PLEGVPLSGCLGDQQAAMVGHQCLNAGQTKNTYGTGTFMLCNIGTRPIISKNgLLTTVGF 293 Caenorhab... WP_003899643 235 apSEPYGVTLAtG------PVGGEVPITGVLGDQHAAMVGQVCLAPGEAKNTYGTGNFLLLNTGETIVRSNNgLLTTVCY 308 Mycobacte... XP_009232964 237 --SEIYGLMKA-G------AL-EGVPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHgLLTTVAY 306 Sumatran ...
2ZF5_O 286 GLNGRVs--YALEGSIFVTGAAVQWLRDGIKIIKHASETEELATKLESNEGVYFVPAFVGLGAPYWDQFARGIIIGITRG 363 Thermococ... CAC36363 303 KIGDQDt-vYALEGSIAVTGSLVQWMRDQMGLISTAAEIETLALTVEDNGGAYFVPAFSGLFAPYWRSDARGVIAGLTRY 381 Streptomy... CAC25769 304 QREGSAp-vYALEGSVSMGGSLVQWLRDNLQLIPNAPAIENLAREVEDNGGVHVVPAFTGLFAPRWRPDARGVITGLTRF 382 Corynebac... AAF27123 302 KLGPQAqtnYALEGSIAIAGAAVQWLRDSLGIIKSASEIEDLAAMVDSTGGVYFVPAFNGLFAPWWREDARGVCIGITRF 381 thale cress FlyBase:CG18374-PA 317 QLGRKAvpfYALEGSVSIAGAAFNWLRDNMNLIQNSGQIETMASTVDNSLDVYFVPAFNGLYAPYWNQDARGVICGLSEE 396 fruit fly FlyBase:CG7995-PA 325 KLGPQAptiYAIEGAVSVAGHALSWLQNKVRILPDSRDAEKYAEMVPTSGDVYFVPAFTGLYAPYWRQNARGIIIGLTQF 404 fruit fly AAF61320 302 QVGRDGpcyYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLK 381 Trypanoso... Q21944 294 QFGADSpvvYALEGSGSIGGNVVRFLRDNFKFISDAKEMEGLCRSVEDTSGAYFVPSFTGLYTPYWDSTARGTILGLTQV 373 Caenorhab... WP_003899643 309 QFGNAKp-vYALEGSIAVTGSAVQWLRDQLGIISGAAQSEALARQVPDNGGMYFVPAFSGLFAPYWRSDARGAIVGLSRF 387 Mycobacte... XP_009232964 307 KLGRDKpvyYALEGSVAIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQF 386 Sumatran ...
2ZF5_O 364 TGREHLARATLEAIAYLTRDVVDEMEK--L--VQIK--------ELRVDGGATANDFLMQFQADILNRKVIRPVVKETTA 431 Thermococ... CAC36363 382 VTKAHLARAVLEATAWQTREIADAMTKdsG--VELT--------ALKVDGGMTSNNLLMQTLADFVDAPVVRPMVAETTC 451 Streptomy... CAC25769 383 ANRKHIARAVLEANAFQTREVVDAMAKdaG--KALE--------SLRVDGAMVENDLLMQMQADFLGIDVQRLEDVETTA 452 Corynebac... AAF27123 382 TNKSHIARAVLESMCFQVKDVLDSMNKdaG--EKGSlnngkgefLLRVDGGATANNLLMQIQADLMGSPVVRPVDIETTA 459 thale cress FlyBase:CG18374-PA 397 TTSEHIVRATLEAVCFQVRDILDSMHKdcK--IPLA--------KLMVDGGMTVNNLFLQLQSDLVGIQVLRAKIAETTA 466 fruit fly FlyBase:CG7995-PA 405 TRKNHIVRAALESICFQTRDILECMHQecG--YEIN--------KLHADGKLTTNNLLMQLQADTIGMPVFRSQLMDSTA 474 fruit fly AAF61320 382 TTRAHVIRAALQAIALQLNDVVGSMKRdaG--LNLS--------SLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTA 451 Trypanoso... Q21944 374 TQREHICLAALRAVAFQSAEMIAAVEQdlEggTKVT--------TLKVDGGMIANKLFNEIQADIMGRDIVTPKITEISG 445 Caenorhab... WP_003899643 388 NTNAHLARATLEAICYQSRDVVDAMEAdsG--VRLQ--------VLKVDGGITGNDLCMQIQADVLGVDVVRPVVAETTA 457 Mycobacte... XP_009232964 387 TNKCHIAFAALEAVCFQTREILDAMNRdcG--IPLS--------HLQVDGGMTSNKILMQLQADILYIPVVKPSMPETTA 456 Sumatran ...
2ZF5_O 432 LGAAYLAGLAVDYWADTREIAELWKAE---RIFEPKMDEKTRERLYKGWKEAVKRAMGW 487 Thermococcus kodakarensis KOD1 CAC36363 452 LGAAYAAGLAVGFWNSTDDLRANWRRA---AEWTPRMDADIRDREYKSWLKAVERTMGW 507 Streptomyces coelicolor A3(2) CAC25769 453 VGVAFAAGLGSGFFKTTDEIEKLIAVK---KVWNPDMSEEERERRYAEWNRAVEHSYDQ 508 Corynebacterium glutamicum AAF27123 460 LGAAYAAGLAVG-FWKEADIFESGEKAknsKVFRPAMEEGIRKKKVASWCKAVERTFDL 517 thale cress FlyBase:CG18374-PA 467 LGAAMAAYKAVEN-RYQMEAPLSKSGPr--EAIKPSISATDRNLRYQKWKMAIDRSLNW 522 fruit fly FlyBase:CG7995-PA 475 FGAAMCAAQADGVNLCQFEPEKRYYENvhyDTFLATTTDVERKERYGKWKRAVERSLGW 533 fruit fly AAF61320 452 LGAALCAGLAAGVWTSLEEVKAVSRREnswKTVSPSGSAMEREAMIAEWREALKRT-KW 509 Trypanosoma brucei brucei Q21944 446 WGAAVAGGIG--AQQISLDEFLQQSSe--dNRYTPQKDDNWRSAELARWKEAVKRSCGW 500 Caenorhabditis elegans WP_003899643 458 LGVAYAAGLAVGFWAAPSDLRANWRED---KRWTPTWDDDERAAGYAGWRKAVQRTLDW 513 Mycobacterium tuberculosis XP_009232964 457 LGAAMAAGAAEGVGVWSLEPEDLSAVTm--ERFEPQINAEESEIRYSTWKKAVMKSMGW 513 Sumatran orangutan
Jiyao W et al.(2023). "The conserved domain database in 2023.",