Conserved Protein Domain Family
PRK07238

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PRK07238: PRK07238 
bifunctional RNase H/acid phosphatase; Provisional
Statistics
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PSSM-Id: 180903
Aligned: 43 rows
Threshold Bit Score: 519.535
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
21220768   10 REFVVEADGGSRGNPGPAGYGAVVLDPVTGEALVEAAEYLGVVTNNVAEYRGLLAGLRAAAEL--------DPDa----T 77 
68535744    1 MRLDVECDGGSRGNPGIAGCGSSVLEGDQE--VAARWEFIAKATNNVAEYQGLINALELAIEVakirgvaaGDL-----E 73 
86740144    5 RRLVIEADGGSRGNPGPAGYGAVVRDAGSGKLLAERADSIGRATNNVAEYSGLIAGLRAAAEI--------APDa----E 72 
158316831   5 RRLVVEADGGSRGNPGPAGYGALVRDAGTGQVLAERAASIGTATNNVAEYEGLLAGLRAAAEL--------DPGa----D 72 
111221655  21 RRLVVEADGGSRGNPGPAGYGAVVRDAADGTVLAERAASIGHATNNVAEYSGLIAGLRAAAEI--------APDa----E 88 
290960926   2 REFIVEADGGSRGNPGPAGYGSVVLDAVTGETLVEAAEYIGVATNNVAEYRGLIAGLKAAYEL--------DPEa----S 69 
182439007   5 RQVVVEADGGSRGNPGPAGYGAVVIDPATGEPLAEAAEYIGVATNNVAEYRGLIAGLTAAKAL--------FPDagdalR 76 
29832420    3 REFIVEADGGSRGNPGPAGYGAVVIDAATGETLAETAEYIGVATNNVAEYRGLLAGLKAARAL--------DPAa----R 70 
269125916  10 RKLIVEADGGSRGNPGPAGYGALVRDALTGEVLAEVAEAIGHATNNVAEYRGLIAGLRAAAEV--------DPAa----R 77 
72162352    7 RRIVIEADGASRGNPGPAGYGARVRDADTGELLAEVASPIGEATNNVAEYRGLIAGLEAAAAI--------DPTa----A 74 
21220768   78 VHVRMDSKLVVEQMSGRWKIKHPDMKPLAAEAARVFPP-GRVTYEWIPRASNKHADRLANEAMDAGARGEAWSPSDstae 156
68535744   74 IQVRMDSKLVVEQMSGRWKIKHPDMKPLAARVKELEATlAAVTYNWVPRAQNKRADELANRAMDDGVGGRWFDDALsfqp 153
86740144   73 LEVRMDSKLVVEQMSGRWKVKHPAMRPLVAEATELAARfPAVRFQWVPRARNADADRLANEAMDAAAAGRAWEPA----- 147
158316831  73 IEVRMDSKLVVEQMSGRWKIKHPSMRPLAAQAAEIAAGlGRVRFVWVPRARNGDADRLANEAMDAAAAGRSWEPS----- 147
111221655  89 VEARLDSKLVVEQMSGRWKVKHPAMRPLADEAAALARTfPAVRYQWVPRARNADADRLANEAMDAAAAGRSWEPS----- 163
290960926  70 VRVRMDSKLVVEQLSGRWKIKHPDMKPLAAEAARVFPP-GRVTYEWMPREQNKHADRLANEAMDAGKRGEQWSPAAstad 148
182439007  77 VHVRMDSKLVVEQMSGRWKIKHPDMKPLAARAAAVLPP-SSVTYEWIPRAQNKHADRLANEAMDAGRDGRQWEASAstaa 155
29832420   71 IRVRMDSKLVVEQMSGRWKIKHPDMKPLAREAAAVFPP-SQVTYEWIPRERNKHADRLANEAMDAGKRGERWSPSTsta- 148
269125916  78 VEVRMDSKLVVEQMSGRWKIRHPDLMPLALQARDAAAAlGAVSYTWVPRDRNAHADRLANEAMDAAARGEPWTR------ 151
72162352   75 VEVRMDSKLVVEQMSGRWKIKHPALQPLARQARQVAASlASVTYRWVPREQNAQADRLANEALDGAVRNWSTQRTEpv-- 152
21220768  157 --ldaaAADRAAPAgrtagsrrtgaasavapagteggdggEPAPDGGGA-----------AAGEplaragrdrvdaaslg 223
68535744  154 aadsaeADGDAAPA--------------------------PAGTAGAEAtgaeavtdaasAPEW---------------- 191
86740144  148 ------VPQSPDPV--------------------------PHHAPTTNR-----------LSGW---------------- 168
158316831 148 ------VPQSPDPL--------------------------PHQAPTTNR-----------LSGW---------------- 168
111221655 164 ------VPQSPDPA--------------------------PHRAPTTNR-----------LSGW---------------- 184
290960926 149 --ldtrASRSAAAAa------------------------pEPSGPPGDA-----------TAGAalaraalagskgkpts 191
182439007 156 --ldapARTVTAPP--------------------------PAQGPPGDQ-----------AAGAararaalasargaaap 196
29832420  149 ----elSARTPAPAa------------------------pEPTGPPGDA-----------AAGAararaalaggrvatsp 189
269125916 152 ------KVTGNDSP--------------------------KPAASTAPA--------------W---------------- 169
72162352  153 -----qAAEPVEPP--------------------------VDQGKTDGT-----------ALGW---------------- 174
21220768  224 agtraatstgasatgtsgtgasat---------------------------gtsgtgasatgapglgvaaetsgeadvra 276
68535744      --------------------------------------------------------------------------------    
86740144      --------------------------------------------------------------------------------    
158316831     --------------------------------------------------------------------------------    
111221655     --------------------------------------------------------------------------------    
290960926 192 tggrtgtdssgggrsagadssdggrsaeppsdggsrsagartpgtgdgsrstahgprttadgprtsttaavdatsaaaad 271
182439007 197 addalfpvp--------------------------------------------------------epgppgarvptaper 220
29832420  190 avpepggtaad----------------------------------------------------tgaraardvasvpadad 217
269125916     --------------------------------------------------------------------------------    
72162352      --------------------------------------------------------------------------------    
21220768  277 akvvaspgwgPPDMGAPATFVLLRHGETPLTPQKRFSGSGgsDPSLSPVGREQAERVAASLARR--------GTIEAVVA 348
68535744  192 -----------HPGGKPTRLWVLRHGQTEMSVKKQFSGLS--DPELTSHGHEQARRAAAYVAGQlaggaggsAGPVAIYS 258
86740144  169 ----------MAPPAPPTTTVLLRHGQTPLSVEKRFSGTV--EAALTDVGLGQAAAVANRLRDE---------PFDLVVS 227
158316831 169 ----------MAPPAPPTTTVLLRHGQTPLSVEKRFSGTV--EASLTDLGLEQAAAAADRLRGE---------PFDAVIS 227
111221655 185 ----------MAPPAPPTTTVLLRHGQTPLSVDKRFSGTV--EASLTDLGMSQAAAVADRLRDE---------PFDLIVS 243
290960926 272 lraaknvasvAPDLGTPATFVLLRHGETPLTPQKRFSGSGgsDPSLSEVGRYQAERVAAALAAR--------GTIQEVVS 343
182439007 221 agvpgtgwgsAPDLGAPATLVLLRHGETALTPEKRFSGSGgtDPELSATGRGQAERAAGHFAAL--------GAVQEIVS 292
29832420  218 vraarnvaspPADLGAPATFVLLRHGETPLTPQKRFSGSGgsDPALSDVGRRQAELVGAALAAR--------GTIQAVVS 289
269125916 170 ----------SKAASAPTTTLLLRHGQTPLSIERRFAGTG--DVPLTEVGREQARAAARALKDR---------GLDVIVT 228
72162352  175 ----------GPADTNPTRLLLLRHGQTPMSVERRFAGIG--DIPLTEVGHEQAKAAARRLAQR---------PVDVVVS 233
21220768  349 SPLARTRETAGIVAARLG--LEVAIEEGLRETDFGAWEGLTFGEVRERHPADLDAWLASPDAEPTgGGESFAATGTRIAA 426
68535744  259 SPLKRTRQTAEAVAEALAtsPRVHVTEALIEMNFGDWEGRTFAEVMDEFPLEHDACFWDSSAAPS-GGESPDDVLARVRP 337
86740144  228 SPLKRARQTA----EALG--RDYVVVDDLRETDFGAWEGLTFAEVREKFPDELNAWLADPHVPPP-GGESLIATVARVAR 300
158316831 228 SPLKRARQTA----DALG--RDYLIDEDLRETDFGAWEGMTFAEVRERFPDELNAWLADPAVPPP-GGESLLSTGARVAA 300
111221655 244 SPLKRARQTA----EALG--RDYVVDDDLRETSFGAWEGMTFGEVRERFPDELNAWLADPNVPPP-GGESLISTVTRVAR 316
290960926 344 SPLARCRETAGIVAARLG--LGMTVEDGLRETDFGAWEGLSFGEVRERYPDDMNAWLASPDAEPTgGGESFAAVAHRVAA 421
182439007 293 SPLRRCRETAAAVADRLG--LDVRIDEGLRETDFGAWEGLTFGEVRERYADDLTAWLASPDTAPTgGGESFAEVAERVAA 370
29832420  290 SPLARCRETAGIVAARLG--IEVSVEEGLRETDFGAWEGLTFGEVRERHPEDMNAWLADPEAEPTgGGESFAAVARRVAT 367
269125916 229 SPLTRCRDTAAEVAAATG--APVRIEEGFRETDFGAWEGLTFGEVRERWPREMEAWLADPAAAPP-GGESFEQVARRVRT 305
72162352  234 SPLRRTLDTAQYVAKECG--LDVEVEEDFREADFGAWEGMTFAEARKHSPQEFHRWLSDPHVPPP-GGESFAEVSRRVTR 310
21220768  427 TRDRLVAAYAGRTVLLVSHVTPIKTFVRLALGAPPESLFRMELSAASLSAVAYYADG------------------GASVR 488
68535744  338 FLRDVARNHPGEDVVLVSHVTPIKSILRHALCASGALYRTLHLDLAGLSVIEIFPDGsngsggevgvnnkgsnkdSAVVR 417
86740144  301 VRDRLLAEQPGGRVLIVSHVTPIKGLAQLALAAEPAVLYRLHLDLVSMTTIDWYSDG------------------PAVLR 362
158316831 301 ARDRIMAQYPAGRVLVVSHVTPIKGLTQLALAAEPTVLYRLHLDLVSITTVDWYSDG------------------PAVLR 362
111221655 317 VRDRLLAEQPGKRVLVVSHVTPIKGLTQLALAAEPTVLYRLHLDLVSLTTIDWYSDG------------------PAVLR 378
290960926 422 TRDALAAAHRGRTVLLVSHVTPIKTLVRLALGAPPESLFRMELSAASLSALAYYADG------------------NATLR 483
182439007 371 ARDRIVARYAGRTVLLVTHVTPIKTLVRLALGAPPEALFRMELSAASISAVAYYGDG------------------NASVR 432
29832420  368 TRDKLLAAYAGRTVLLVSHVTPIKTLVRLALDAPPQSLFRMELSAASVSAVAYYADG------------------NASVR 429
269125916 306 ALDKLTVRHRHQKVLVVSHVTPIKLLVREALQAPMDALYRMHLDVSSLTQIDWYADG------------------PAVLR 367
72162352  311 ARDRVLARHRGRTVVVVTHVTPIKLLVQQAMLAPLPALYRMHLDVACLCEVHCFSDG------------------PMVVR 372
21220768  489 LFNETSHLR 497
68535744  418 RVNDTHFLD 426
86740144  363 GFNDTHHLA 371
158316831 363 GFNDTHHVA 371
111221655 379 GFNDTHHSA 387
290960926 484 LLNDTSHLR 492
182439007 433 VLNDTSHLR 441
29832420  430 LLNDTSHLR 438
269125916 368 AFNDTHHLP 376
72162352  373 SLNDTGHLA 381
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