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COG0575: CdsA 
CDP-diglyceride synthetase [Lipid metabolism]
Statistics
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PSSM-Id: 223648
View PSSM: COG0575
Aligned: 66 rows
Threshold Bit Score: 54.2444
Threshold Setting Gi: 13541017
Created: 7-Oct-2002
Updated: 16-Jan-2013
Structure
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Aligned Rows:

COG0575 is a member of the superfamily cl17511.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586479    61 NFFIRTVWTFVMI------------SGFFITLASG-HAWCIVLILGCQIATFKECIAVTSASGREKnlpLTKTLNWYLLF 127
gi 14600705   1 ---------------------maleLAVDWR----------IDNILEAIILMLPAMIANATPVVAG---GRRPVDMGVVL 46
gi 20092121   1 ---------------------------------------------------MLPAYLSNPFAAVFG---GGKPIDGGRTY 26
gi 15669796   1 ---------------------------MFYR------------LLFASLWYILPAYVANASACIFG---GGTPVDLGKNF 38
gi 20094509   1 ---------------------mvemGSGAW------------LELGKGLWFILPAYIANLSACLFG---GGRPLDFGKKL 44
gi 15678852   5 SANVIYLILEIIHvssslnlthshgVLKFLRGVQVnTDIINIIDVLYVIYFMLPAYMANISGLVFG---GGKPLDMGITL 81
gi 15897678   1 -------------------------MSIAY-------------DLLLSILIYLPAFVANGSGPFIK---RGTPIDFGKNF 39
gi 13541017   1 --------------------------------------------MAQAIILFVPALIANSGAVLTG---GYFVLDRGKNF 33
gi 16081274   1 ---------------------------------------------MQSIILFIPALIANSGAVITG---GHFIIDRGKKF 32
gi 15790955   1 -----MGGIIPTSrsphvlntrplgIRGFLPGARPpTRMDLVGTVVVAVWAMLPAYVPNNAAVLAG---GGRPIDGGRSL 72
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586479   128 TTIYYLDGKSLfkffqatfyEYPVLNFIVTNHkficycLYLMGFVLFVCSLRKGFLKFQFGSLCVTHMVLLLVVFqahli 207
gi 14600705  47 PDGRRLLGDGK---------TIEGLLAGFAAG------SAAGVLAALAS-----------GNMLLAVH------------ 88
gi 20092121  27 KDGRRILGDGK---------TYRGLFSGIFCG------FLAGCIEIWLSMRG----FEIMGIKMPTFGPNYASALi---- 83
gi 15669796  39 IDGRRLIGNGV---------TYRGCIFGILCG------TLVGLIQGILVDFNIFNSLDFYGTVLDHVIL----------- 92
gi 20094509  45 SDGRRLLGDGV---------TIRGFIVGVLAG------AVVGLGEGLVV-----------GDPWKAGD------------ 86
gi 15678852  82 ADGRRLIGDGV---------TWRGTAAGTFVG------LVVGIIQGLLS-----------GSIIIGVIT----------- 124
gi 15897678  40 VDGRRLFGDGK---------TFEGLIVALTFG------TTVGVIISKFF---------T----AEWTLI----------- 80
gi 13541017  34 IDGRRILGDGK---------TLSGYLGGSFIG------IVSGVIIYWISYATH-FILGNYGSIALSIEI----------- 86
gi 16081274  33 IDGRRILGNGK---------TLSGYAGGIAIG------TVTGFIIYLISTLFN-YALGTYGTLAEAIII----------- 85
gi 15790955  73 G-GRRLLGDGK---------TWRGTAVGTAAG------VALAVALNALRPAA----ADALGVVLPAFPP----AAm---- 124
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586479   208 iknvlnglfwFLLPCGLVIVNDIFAYLCGITFGKTkLIEISPKKTLEGFLGAWFFTALASIILTRILSpytyltcpvedl 287
gi 14600705  89 ----------SPAIALGALAGDMAGSFVKRRLGIE-RGRPAPLLDQLDFYLGALAVSIALGYTWTPR------------- 144
gi 20092121  84 ---------vVLALPSGALFGDMFKSFFKRRMGLK-RGASLPLVDQLDFVVGAWFFTYLAAPEWFVSN------------ 141
gi 15669796  93 ----------AFFLSVGAIVGDAVGSFIKRRLNIE-RGKPAPLLDQLDFVIGALAFGYIVAPIPYEM------------- 148
gi 20094509  87 ----------GFILGLGAMAGDAVGSFVKRRIGLE-RGAPAPVLDQLDFFVGAVLL-YYLVYGWHPPG------------ 142
gi 15678852 125 ----------GLLLGFGALMGDAAGSFIKRRLKID-RGRPAPILDQLDFVFGALILVSPIVVLPIDY------------- 180
gi 15897678  81 ----------SFLESLFAMIGDMIGAFIKRRLGIP-RGGRVLGLDQLDFVLGASLILVLMRVNITWY------------- 136
gi 13541017  87 ----------PAVMAFGSLTGDILGSFVKRRIGIK-SGGKGGLLDQWPFALVAFLFLFLMERPFFLHY------------ 143
gi 16081274  86 ----------PFIMATGSLTGDIAGSFVKRRIGID-RGGKGGLLDQWPFALMAFLFLYIFERPFFMYH------------ 142
gi 15790955 125 ---------gTLAF--GAMVGDIAASFLKRRTGRQ-RGAAFPVVDQLDFVVVALALTALAVPAWVGDT------------ 180
                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 586479   288 htnffsnltcelnpvflpqvyrlppiffdkvqinsitvkpiyFHALNLATFASLFAPFGGFFAsGLKRTFKVKDFGH 364
gi 14600705 145 ----------------------------------------------VAVEAAAAVLLLHLAAN-ITAYLLGLKKVPW 174
gi 20092121 142 ------------------------------------------FTTGIALTVLIMTPLLHLTTN-IIGYFIGVKKEPW 175
gi 15669796 149 -----------------------------------------------IIIICLFTVFVHLLGN-IIAYKLGIKDVWW 177
gi 20094509 143 ------------------------------------------W---VLVGLAILTLALHWLTN-VIGYLLKLKEVPW 173
gi 15678852 181 -----------------------------------------------IILIMLITLVLHLSAN-IIAYLLGMKDVWY 209
gi 15897678 137 ----------------------------------------------QFLFICGLAFFLHQGTN-YVAYLLKIKNVPW 166
gi 13541017 144 ------------------------------------------YFFAGIIVILAIVPPLHRAVN-IIGYKLHKKDVPW 177
gi 16081274 143 ------------------------------------------YFYVTMIVILVIVPPIHRAVN-IIGYKMHKKDVPW 176
gi 15790955 181 ------------------------------------------FGLPVLVTVAVLTPALHLLTN-GIAYALGVKDEPW 214
Citing CDD
Marchler-Bauer A et al. (2013), "CDD: conserved domains and protein three-dimensional structure.", Nucleic Acids Res. 41(D1):D384-52.
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