Conserved Protein Domain Family
SecD

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COG0342: SecD 
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport]
Statistics
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PSSM-Id: 440111
Aligned: 801 rows
Threshold Bit Score: 139.865
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_128151900   1 MKgKg--fVKFFaivlSLIcLAELfptfyvnrieskanslsngteaskrteleklakdtlnlgivklnyfdakKKEMKLG 78  
WP_011011287   3 WR-RillnFRVIvl-iFFL-LISIta---------------------------------------------laTRGLTFG 34  
WP_048165722   3 WK-NlllnWRVLll-lIFV-IGSFas---------------------------------------------iiAYGLTFG 34  
WP_010868888   3 WK-KillnGRVIll-tLFL-IMSIvs---------------------------------------------laTRGLTFG 34  
WP_011171467   1 -M-KllkdHKVVil-lVCV-LASLll---------------------------------------------iaFKGISFG 31  
WP_011250545   5 LK-KillnWKVLll-iIFL-IGSIgs---------------------------------------------lyTRGLTFG 36  
WP_013799808   1 -M-KllkdSKILil-lISL-VASIll---------------------------------------------iaFKGVSLG 31  
AAM02222       4 LG-WmkenWRLLvi-tAVW-IVAAts---------------------------------------------laVKGVNLG 35  
WP_013866714   1 -M-KllkdSRILil-iGCI-VLSIll---------------------------------------------isFKGISYG 31  
WP_010869603   3 IS-KllkdRKILil-iIFV-TLSVfl---------------------------------------------ivFKGLDFG 34  
WP_128151900  79 LDLKGGLNLLLEisekdllldladnsenpvfrkaldiatsqevksnatytsnffkafesakkelgqpdlklsspdvfgtk 158 
WP_011011287  35 LDISGGISITVK-------------------------------------------------------------------- 46  
WP_048165722  35 LDISGGTAITVR-------------------------------------------------------------------- 46  
WP_010868888  35 LDISGGISITVK-------------------------------------------------------------------- 46  
WP_011171467  32 VDLSGGSTIVLQ-------------------------------------------------------------------- 43  
WP_011250545  37 IDISGGVALIAQ-------------------------------------------------------------------- 48  
WP_013799808  32 IDLSGGSIIVLK-------------------------------------------------------------------- 43  
AAM02222      36 LELKGGTMVIAK-------------------------------------------------------------------- 47  
WP_013866714  32 VDLSGGSIIVLK-------------------------------------------------------------------- 43  
WP_010869603  35 IDLSGGTIIVLK-------------------------------------------------------------------- 46  
WP_128151900 159 dlsgqiqyntsdanvekyISG-VVESKVNKAIDVIRARIKKLNIDEPNIARVpgTGRILVEL-PGVtDA----DRVKKLL 232 
WP_011011287  47 ------------------LEKpVDSQTMEQVKIALEQRLNTLGVKNIVVEPWg-DQFVIVKV-ANV-TEee-aDQLIKTI 104 
WP_048165722  47 ------------------LEKpVDQNTMDKVVTSLTNRINRLGIADVKVEPWg-DQYIIVKV-ANV-SEdt-vRGIKETI 104 
WP_010868888  47 ------------------LEKpVDTQTMEQVRIALEQRLNALGVKDITIEPWg-NQFVLVKV-AGV-NEee-aNQLVETI 104 
WP_011171467  44 ------------------TESeLSESEMTTVNEILTSRLNTNGLSDVRIYPRg-SDEIVIEIpESA-DL----ERIQKIL 99  
WP_011250545  49 ------------------TEEpVDSKTMELVVDSLQKRLNTFGLRDISVEGQg-NSIVVVKV-ANV-SSteeaNQLKQVI 107 
WP_013799808  44 ------------------SERpMTDEEITLTVDILGKRLNANGLSDVRIYPRg-NDEIIVEIpKSA-DL----ERIEKIL 99  
AAM02222      48 ------------------TDHpVSKKEMDQTVTVLESRLSTFGFKGIKIQPVg-RDHIIVML-PGT-PP----KEAVELI 102 
WP_013866714  44 ------------------TNEpLSEQNMTVVTTILSNRLNTNGLSDITVYPRg-NDEIVVEIpKTA-DL----DRIKKIL 99  
WP_010869603  47 ------------------AEKpMSDKEIEATIKIITERLNYNGLNDVVIYPRg-NDEIIVEIpKSC-DT----DRIIKIL 102 
WP_128151900 233 QTSARLEFWEVFdqasvwaylmdanqkiannklsallapsnrsnavavakiqdtaavnqiifsdkakkllpvslkyskfl 312 
WP_011011287 105 ERQGVFYAEFQG-------------------------------------------------------------------- 116 
WP_048165722 105 EKQGVFYAEFEG-------------------------------------------------------------------- 116 
WP_010868888 105 ERQGVFYAEFQG-------------------------------------------------------------------- 116 
WP_011171467 100 TQQGVFTAVIDN-------------------------------------------------------------------- 111 
WP_011250545 108 ESQGVFFMEFNG-------------------------------------------------------------------- 119 
WP_013799808 100 SKQGVFVAKIDN-------------------------------------------------------------------- 111 
AAM02222     103 TKPGRFEAKYKG-------------------------------------------------------------------- 114 
WP_013866714 100 TQQGVFIAKIDN-------------------------------------------------------------------- 111 
WP_010869603 103 KQQGVFVAKIDN-------------------------------------------------------------------- 114 
WP_128151900 313 waskpdsrfpnelelyairgtknnKAPLVG-AVTEAHI-TFD-Q-FN-RIQISMQMSPESAVTWKDLTKRNiGKPIAVVL 387 
WP_011011287 117 ------------------------IIFATGkDILNVGSvSYDpQhSA--WVVPFRLSKEAAEKFAQLALGKaGYPVDMFL 170 
WP_048165722 117 ------------------------EIFATGeDIVQVFEyRIEpStYR--WHVPFQISQKAAERFAQLALNKpGYPVDMFL 170 
WP_010868888 117 ------------------------VIFATGkDILNVGSvSYDpRqSA--WVVPFRLSKDAAEKFAKLALGKaGYPVDMFL 170 
WP_011171467 112 ------------------------QTAYTGqDVSYVEEpGMTaSg----YGVGFKLTLDGAQKFADVAYGKgGYPVELYM 163 
WP_011250545 120 ------------------------VVFGTGkDITYVGPyEIKsDnS---WAVPFRISKSAAEKFAELAKGKaGWPVDMFL 172 
WP_013799808 112 ------------------------ITAYTGkDVKSVEIpQKIpQgNSwAYGVPFELTLEGAKKFAEVAKGKaYHRVELYM 167 
AAM02222     115 ------------------------KTVITGqDIESVESpRIErVeGGyQWSVPFRLTAEGARKFAEVAKNApGQPIDMYL 170 
WP_013866714 112 ------------------------ITAYTGqDVAYVEEpGNTpSg----YGVSFKLTSEGANKFAKVAYGKgGHTVELYM 163 
WP_010869603 115 ------------------------ITAYTGsDVQNVELpTKIpQgETwAYGVPFELTLEGAKKFAEVAKGKaYHKVELYM 170 
WP_128151900 388 DEVVYTA------------------------------------------------------------------------- 394 
WP_011011287 171 DPPVNSTlvvsnrvyeamlsktfmlegdmtlveriekafgikvvpyanvtpeeiaeia-kgseriilldvdgnlskalke 249 
WP_048165722 171 DPPVNSLllvsqetynvmkdefnaqapqamslperikkafnidtvvyanqsideivdlakdkdlvvligvngnlkdeles 250 
WP_010868888 171 DPPVNSTlvvskdfydalnsprfmfegnmtlaeriekafnikiikynnqtaqeiakia-kgsekvllvdvdgnlekqlka 249 
WP_011171467 164 DEKAISA------------------------------------------------------------------------- 170 
WP_011250545 173 DPPINSLlvvpqdvfmtmngtafnagapdapplaariekalnittimytnqsatelkemangraivlagvprelydglkd 252 
WP_013799808 168 DGKLISA------------------------------------------------------------------------- 174 
AAM02222     171 DNKKVSS------------------------------------------------------------------------- 177 
WP_013866714 164 DGKLVSN------------------------------------------------------------------------- 170 
WP_010869603 171 DGKLISA------------------------------------------------------------------------- 177 
WP_128151900 395 -----------------------------PNVNTEIp-----N---GQSIIS-GNF-----SEQEANDLVDVLKSGNLPA 431 
WP_011011287 250 mgfevetrsmrsdedvydfikrslglygpYRVSEGLa----tGnpsTEVMISiTAPktdiqARQDAQVVSVVLRSGSLPV 325 
WP_048165722 251 rgvrvrviergkdettydlitkalglygpYSVGEGLt----hGqaaTNVEIT-GSSsnpylAQQEASIISVVLASGSLPI 325 
WP_010868888 250 lglkvevwkrgndedmesfvrrvlrlygpYRVGEGLa----tGrasTEVMISiGGSqndlkARNDAQVVAVVLRSGSLPV 325 
WP_011171467 171 -----------------------------PLLSADLa----dGnihQNQVITvAGSnpteeDIDEAWVIYTALKSGSLPV 217 
WP_011250545 253 mnvsvkyipsepsadttsfvkeilglygpYSLGEGLa----nGvpqTDVQIT-GRAsnrveAEREAKTVYTVLKSGSLPV 327 
WP_013799808 175 -----------------------------PVLAEELt----dGkphPRQVITvGPYpptkeEEDEAMAIYTALKSGSLPV 221 
AAM02222     178 -----------------------------PRISEDLamaaasGhmeREIEIV-GGAktkeqAEREAKEIMAVLRSGQLPA 227 
WP_013866714 171 -----------------------------PTLSPGLa----dGkphPDQIITvSGSnptksDEDEAWAIYTALKSGSLPV 217 
WP_010869603 178 -----------------------------PVLSPDLa----dGkphPQQVITvGAYpptkeEIDEAMAIYSALKSGALPV 224 
WP_128151900 432 KAKIIQSEIVGPTLGQQSINNGLLSIVVSYVFILAWMLFYYGKAGLYANI-ALII-NLFFLIGIMASTGAVLTLPGIAGI 509 
WP_011011287 326 KLSIERIDYISPKLGENFKRQVLVAGIAALLVVGLIVFLHYRKIKIAIPVmFTSFsEVLIILGIAALIRWNLDLPSIAGI 405 
WP_048165722 326 KVYVEGTQYISAELGRDFKNQVLIAGIAALLVVGAVVYAHYRKLRIAIPVvSTSLsEVIIILGVAALIKWNLDLPSIAGI 405 
WP_010868888 326 KLSIERIDYISPKLGEDFKRQVLIAGIAALLVVGAIVYLHYRKLKIAIPVmFTSFsEVLIILGIASIIRWNLDLPSIAGI 405 
WP_011171467 218 KVHIEYISSVSPTLGSEFIKGSVIAGIFAFIAVAAVISFRYKNPKIVLPIlITGFsEVLLILGFASLIDWKLDLASIAGI 297 
WP_011250545 328 KLKVISMEFISPKLGQDFKKQALYAGLAALVAVLLIVYFHYRNWKIAIPVaSTSLfEVIIILGIAALIKWNLDLPSIAGI 407 
WP_013799808 222 KVEIEYVSSISPTLGKEFVKGALIAGLLAFIAVGLVVGVRYKQPKIVLPIlFTCAsEILLILGFASLIDWKIDLASIAGI 301 
AAM02222     228 KLVPEGVYSVSATLGQNFLKMAMIAGAIAFAAVSVIIALRYRDIRISGPIlFTGSsEVVFLIGLASLTGFTIDLPALAGI 307 
WP_013866714 218 KLHIEYISSISPTLGKEFINGAIIAGLFAFLAVGAVVAIRYKKPMIVLPImITCAsEILLILGFASAIGWKLDLASIAGI 297 
WP_010869603 225 KLDIEYISTISPEFGKEFLKGTAIALLLAFIAVGIIVSIRYKQPKIAIPIlITCIsEVIIILGFASLIDWKLDLPSIAGI 304 
WP_128151900 510 VLSMAMAVDANIIIFERVKEELRLGKP---LKQAFMEGQKHALAAIIDGNLTTLIVGIVLL-FSTGPIKGFAVTLVIGIF 585 
WP_011011287 406 IAAIGTGVDQQIVITDELLGEEES--RrrvKRSGVLRRMGRAFFIILASATTTIVAMSFLFkFFVGGLRGFAFTTILGVL 483 
WP_048165722 406 IAAIGTGVDQQIVITDELLGSQRK--EritKRSGVLKRMGRAFFVILASATTTVVAMSFLFkFFVGGLRGFAFTTILGVL 483 
WP_010868888 406 IAAIGTGVDQQIVITDELLGDVTAGKKrivKRSGILKRMGRAFFIILASASTTIVAMSFLFkFFVGGLRGFAFTTILGIL 485 
WP_011171467 298 IAAVGTGVDHQIVITDETISGEAK---------KVTKSIKRAFFIIFGAAATTIAAMLPLFvMGIGMLKGFAITTIAGVL 368 
WP_011250545 408 IAAIGTGVDQQVVITDELLGGERS--TritRRAGALKRIGRAFFIIFASAATTIAAMSFLLvYFVGTLKGFAVTTIIGVL 485 
WP_013799808 302 IAAVGTGVDDQIVITDEVLK-GTK---------KLKKSIKRAFFIIFAAAGTTIAAMTPLFvMGVGMLKGFAITTIAGVL 371 
AAM02222     308 ILSIGSGVDDLIVITDEIVRGERRk-----eEVTLRQRIKRAFSVVLASFATLAAAMAVLFvAGMGLLKGFAIMTIAGAF 382 
WP_013866714 298 IASVGTGVDDQIVITDETLSRESN---------RVKKSIKRAFFIIFASAGTTIAAMLPLFaMSIGMLKGFAITTIAGVL 368 
WP_010869603 305 IAAVGTGVDNQIVITDEALKRGAG---------KIRASIKRAFFIIFASAATSIAAMLPLFvLGVGMLKGFAITTIAGVL 375 
WP_128151900 586 CTLFTAIFITGMLIYGAMDKG 606 
WP_011011287 484 VGIFITRPAYGEIAKVLIGER 504 
WP_048165722 484 IGISITRPAYAEIAKMLLSEK 504 
WP_010868888 486 IGILITRPAYGEIAKVLIGER 506 
WP_011171467 369 MGISISRPAFSRIIQYVLKH- 388 
WP_011250545 486 IGIFVTRPAYAEVAKYLIGEE 506 
WP_013799808 372 IGVFITRPAFARIIKYIV--- 389 
AAM02222     383 YGVVITRPVYADLLKKILGTE 403 
WP_013866714 369 IGIFITRPAFARIVQYVIKKE 389 
WP_010869603 376 IGIFITRPAFARIIEEMFKKF 396 
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