2NBB,2MXT


Conserved Protein Domain Family
NURR_hnRNPQ

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cd21066: NURR_hnRNPQ 
NURR (N-terminal unit for RNA recognition) domain found in heterogeneous nuclear ribonucleoprotein Q (hnRNPQ) and similar proteins
hnRNPQ, also termed glycine- and tyrosine-rich RNA-binding protein (GRY-RBP), or NS1-associated protein 1 (NSAP1), or Synaptotagmin-binding, cytoplasmic RNA-interacting protein (SYNCRIP), is a highly conserved RNA-binding protein that mediates the exosomal partition of a set of miRNAs. It acts as a component of the hepatocyte exosomal miRNA sorting machinery. The model corresponds to NURR domain of hnRNPQ, which has structural similarity to bacterial protein Barstar and binds to Apobec1.
Statistics
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PSSM-Id: 410954
Aligned: 11 rows
Threshold Bit Score: 165.212
Created: 30-Nov-2018
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2NBB_A         1 GSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTY 80  human
2MXT_A         1 GSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTY 80  human
Q7TMK9        23 HSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTY 102 house mouse
NP_999861     23 HSDHFNTLLEAGLPQKVAEKLDEIYLAGLVAHSDLDERAIEALKEFNEEGALQVLIQFKESDLSHVQNKSAFLCGVMKTY 102 zebrafish
NP_001026254  23 HSEHFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTY 102 chicken
O60506        23 HSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTY 102 human
NP_001084953  27 QSEHTQTLLDAGLPQKVAEKLDEIYIAGLVAHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTY 106 African clawed ...
AAI61767      38 QSEHMQTLLDAGLPQKVAEKLDEIYISGLVTHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTY 117 tropical clawed...
EMP42604      23 HSEHFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTY 102 Green sea turtle
XP_007892052  28 RSEHYQTLLDAGLPQKVAEKLDEVYIAGLVAHSDLDERAIDALREFNEDGALSVLQQFKESDLSHVQNKSAFLCGVMKTY 107 elephant shark
XP_014351830  23 HSEHFQTLLDAGLPQKVAEKLDEIYIAGLVAHSDLDERAIEALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTY 102 coelacanth
2NBB_A        81 RQREK 85  human
2MXT_A        81 RQREK 85  human
Q7TMK9       103 RQREK 107 house mouse
NP_999861    103 RQREK 107 zebrafish
NP_001026254 103 RQREK 107 chicken
O60506       103 RQREK 107 human
NP_001084953 107 RQREK 111 African clawed frog
AAI61767     118 RQREK 122 tropical clawed frog
EMP42604     103 RQREK 107 Green sea turtle
XP_007892052 108 RQREK 112 elephant shark
XP_014351830 103 RQREK 107 coelacanth
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