2XWU,2X19


Conserved Protein Domain Family
Importin_rep
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pfam18773: Importin_rep (this model, PSSM-Id:408544 is obsolete and has been replaced by 436727)
Importin 13 repeat
Importin 13 has a spiralic structure containing repeats structurally similar to HEAT repeats. It serves as receptor for nuclear localization signals (NLS) in cargo substrates, mediating docking of the importin/substrate complex to the nuclear pore complex (NPC). It contains several repeats structurally similar to the HEAT repeat. This Pfam entry represents a single repeat unit.
Links
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Statistics
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PSSM-Id: 408544
Aligned: 16 rows
Threshold Bit Score: 78.5503
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2XWU_B       402 QFPSDEEyGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAE 441 
XP_008198199 414 MFPLNED-GDWSLDDKEVFRCYRQDIADTFIYCYNVLNLE 452  red flour beetle
XP_018334259 414 qYPGSWEeSGWSLDDQEVFRCYRQDITDTLMYCYNILNVE 453  emerald ash borer
XP_002128195 392 KYPQDNShNEWTADEKEQHRIYRIDISDTLMYLLEMLHTD 431  vase tunicate
XP_017328195 391 RFPNQHDyASWSSDDKEQFRTYRVDISDTLMCLYELLGPE 430  channel catfish
XP_694685    385 CFPRDEDfTAWSADDKEQFRTYRVDISDTLMYTYELLGPE 424  zebrafish
XP_014342856 394 QFPTDEEyGTWSSDEKEQFRIYRVDVSDTLMYVYEMLGAE 433  coelacanth
KOF80503     239 QYPPDQEyNSWSTEQKEQFRCYRHDIGDTMMYSFTILKDF 278  Octopus bimaculoides
EKC31329     329 QYPEEEEyNSWTKDDKEEFRCYRQDIGDTMMYSYSILREP 368  Pacific oyster
XP_013073345 386 RHPPEADySSWSLEEKEKFRCYRQDIGDTLMYSYNILGVE 425  Biomphalaria glabrata
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