3DLU,1KVV


Conserved Protein Domain Family
SRP19
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pfam01922: SRP19 (this model, PSSM-Id:396484 is obsolete and has been replaced by 460383)
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SRP19 protein
The signal recognition particle (SRP) binds to the signal peptide of proteins as they are being translated. The binding of the SRP halts translation and the complex is then transported to the endoplasmic reticulum's cytoplasmic surface. The SRP then aids translocation of the protein through the ER membrane. The SRP is a ribonucleoprotein that is composed of a small RNA and several proteins. One of these proteins is the SRP19 protein (Sec65 in yeast).
Links
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Statistics
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PSSM-Id: 396484
Aligned: 200 rows
Threshold Bit Score: 64.8018
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3DLU_A                 5 VVWPSELDSRLSRKYGRIVPRSIAVESPRVEEIVRAAEELKFKVIr--vEEDKLNPRLsgideELrt------------- 69  Pyrococ...
WP_022532979          10 VLWPEYFDSGLTRAQGRRLPTALCVKQPSLDMIAKGAILLDLEYRv---IEDKSYPSD-----WPsk------------- 68  Candida...
EHY64888               5 rIYPIYFNRGIKRSQGRKVPFSSNSKPVTLQQLLKALIQLKIEYKv---E-TKQHPKHs----YAlcaeclpaatkpeev 76  Nematoc...
EIJ87917               5 rIYPIYFNSGIKRSQGRKVPFRNNAKAVTLQQLLKALNQLKIEYTv---E-TKQHPKHs----YElcaqflpstskpeev 76  Nematoc...
jgi:Nmar_0519          8 VIWLDYFNKNLKKSKGRRLGLEKCVFDPSLKELTDAAKAAGFEITe--sDDKVRFPKRp----FVr-------------- 67  Nitroso...
goetting:Ngar_c15270   8 VLWLDYFNKNLKRRQGRKVNREQAVFDPTVQELAEAAKAAGFQFSdqevNDNARFPRRs----FTr-------------- 69  Candida...
A1RX38                 8 IVWPVYFDSTKPRKW-RRVPRKLAVEKPTLSEIVEAVKREGFSFTv---EENAKHPAY-----WYev------------- 65  Thermof...
Q9YDZ7                19 ILWPAYFDSTLPRRLGRRVPRDMGVPSPKPEDVAEAARRAGFEAVv---E-ESSYPRL-----WWrv------------- 76  Aeropyr...
BAJ47268               8 ILWPVYFDSKSSRKQGRRVSRGLAVQRPSADDLAAACRRLGYEVE----KNDAAYPRR-----WSrr------------- 65  Candida...
jgi:Vdis_2405          8 IIWTVYFDSSKSRGFGRKVPSNVAIKSPTIDELVKAISNLGLEFEv---YGDKKHPGN-----WFeg------------- 66  Vulcani...

3DLU_A                70 -------fGMIVLES--P----Y--GKSKSLKLIAQKIREF 95  Pyrococcus furiosus
WP_022532979          69 -------rGCVRVEK--G----Km-KKSEILPKIGEILVKn 95  Candidatus Methanomethylophilus alvus
EHY64888              77 erlfsttgGSVMIT---T----D--SKRQLIKEINDLLSTn 108 Nematocida sp. 1 ERTm2
EIJ87917              77 erlfsttgGAVKIT---T----D--SKRQLIKDIDNLLngs 108 Nematocida parisii ERTm3
jgi:Nmar_0519         68 -------sGYVVLPK--G----S--SKTKILNKISEKLVAK 93  Nitrosopumilus maritimus SCM1
goetting:Ngar_c15270  70 -------sGYVMVAKke------gvKKSQVIDAVAEKIVQR 97  Candidatus Nitrososphaera gargensis Ga9.2
A1RX38                66 -------qGRVIVQA--N----V--KKSVLLKKIAENLQKI 91  Thermofilum pendens Hrk 5
Q9YDZ7                77 -------rRRIVVLApeD----V--SKTDIIKAVATELRKI 104 Aeropyrum pernix K1
BAJ47268              66 -------tGYVVVKPrp------kiSKNMFLKMVAEELRKH 93  Candidatus Caldiarchaeum subterraneum
jgi:Vdis_2405         67 ------pyGYVAVKKesairrfgsiNKRRLLMLIARELVRI 101 Vulcanisaeta distributa DSM 14429
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