25407027 1036 IWEVMTFKR---GMNFWEYPLPNLEILIFSTFFIWRLLDISFNKIGlrVPRFTYMMIVRIILGQTCHFSNKSWIHDIFFp 1112 thale cress 15219224 1 --MDPKMLFclpEGDALFNPLNTMFIQMACILVFSQFFYLFLKPCG--QAGPVAQILAg-IVLs-LLTIIRKVHEFFLQ- 73 thale cress 25411916 -------------------------------------------------------------------------------- thale cress 15231125 3 STTTKNVCGdkwYLNLDRPEEALKILVFIAIFVVRTLLHYLMKPLG--QPYLTTDFAIg-LIL----GNIPRFRGAFSG- 74 thale cress 7444648 1 ---------------------------------------------------------------------MEFNCLPPTFi 11 thale cress 25407295 1 -MVKQHSVRlkhCVFTVKSSVPVYSEGVNDGIKLHSFGNLVKKKVF----LDTSKRFY--FQG--RWSESSGRRVETYAg 71 thale cress 15241036 19 PWVGAGSLGigrGENPLKFALPLLLLQISVFSIFSVSFQFLLRPFG--KFAFLTQMLAGICLGPSVIGRNKQYMATFFY- 95 thale cress 10177870 -------------------------------------------------------------------------------- thale cress 15237673 45 QVHDKQPFGmfkGENGMNYTFSTFLIEAILIIFFIKIVYVLLRPLR--QPRIVCEIIGGMMIGPSMLGRNRNFNYYLFPp 122 thale cress 19114377 10 MSTQSIFDGdnvVVYSASDPLLLFIVQAIIIIALCRLIHIPLSFLQ--QPRVIAEIIGGIVLGPTVMGRIPKFLDYIFP- 86 fission yeast
25407027 1113 dDNRPKVAETLGAFGFVLYWFLKGVTMDAELPFRTEKRSSV-IGFITVIIP-LICGSLTFR----YRERRGDSSILRMEY 1186 thale cress 15219224 74 -KDSASYYIFFSFLLRTAFVFLIGLEIDLDFMKRNLKNSIV-ITLGSLVISgIIWLPFLWFli-rFMQIKGDFLT---FY 147 thale cress 25411916 1 ----MRLLTLLLIC-TFFFFFSFAYSAESDNETDSVVTRE--INGTVVESNa----TSAKPredsFADMIDRALEKEFPD 69 thale cress 15231125 75 --PYSITLNNIIEFGMICHMFVMGLEMNPSVLLRPPTKDAF-IAYTSMITTfVLAFVTTPFlhytKTSPYIFS------- 144 thale cress 7444648 12 tLRLMRRKLPFSMCCGYCLQASYSCL-YFRKFLEVTPVLGY-LAAGILIGPyG--LSIIRNvhgtKAIAEFGVVFLLFNI 87 thale cress 25407295 72 -VDVASAVDVINDLGFDTLTFLMVTVIIVPAFRILKASPILgFFFAGVVLN---QFGLIRNltdvKVLSEWGILFLLFEM 147 thale cress 15241036 96 -ARSVYIIESFEAICFLFICYITTCQVDTRMIKRVGKLAFI-NGILLFLIPfVWGQFAAILi--sKRLKSGPAGIPPVEF 171 thale cress 10177870 1 ----MARFAVIGL--TFLLLLGTSLSARSDEE-----TRER-FYGNVVNS------TAPGNgegsIAKMFDRVLEKEFSE 62 thale cress 15237673 123 --IANYICANIGLMGFFYFFFLTAAKTDVAEIFKAPRKHKY-IAAVSVLVP-IACVGSTGAa---LKHKMDIRLQKPSSI 195 thale cress 19114377 87 -TSSMGPLNLVSNLGLVLFLFVIGMEVDLRVLVLNYKVTLL-VTVFSIVIPfGAGAGISAGlykfTTREFEFGk----FL 160 fission yeast
25407027 1187 RLIIFLQSISAFTSIDTLLKDLQIKHSEFGRIALSGAMVTDMLAFGVTFFNAIYYEKLY--------G---FMQTVGFCL 1255 thale cress 15219224 148 LAFLITLSNTAAPVVIRSIIDWKLHTSEIGRLAISCGLFIEITNIFIYTIVLSFISGTm------------TADIFIYSF 215 thale cress 25411916 70 NDQNEVPDPGSFNNSVADQ----------------QAVLETVARV---KPKKNETK---------------TK--EEKSF 113 thale cress 15231125 145 LALSLMASSTGSPILTRVIANLKIRKSDLGKLASAAGVHTDMISTLLYCFGFIFFPTEKplarplhrFfraLLMFCLFLA 224 thale cress 7444648 88 GLELSVERLSSMKKYVFGLG--------------SAQVLVTAAVIG-LITHYVAGQ---------------AGPAAIVIG 137 thale cress 25407295 148 GLELSLARLKALAKFAFGMG---LTQVLLCTAAFTAFELPPNGAIGTKILEFLFHSRPDl------vNi-rSIDEAVVIG 217 thale cress 15241036 172 HHVAIVQSTMFFQVVYGVLSSLKMLNTEPGRLALASMMVHDCLSWCFFMLNIAIKLNVDlpnk-nraAflsVLQTEMNAD 250 thale cress 10177870 63 NDSPEGSDGASFNSSVADQ----------------QAEIETVAKVTHEKGKRNDTQENNg-----------TRPFQLQDV 115 thale cress 15237673 196 GGVTFALGFTSFPVIYTVLRDMNLLNSEIGKFAMSVTLLGDMVGVYVLVLFEAMAQADGgg-----gAysvIWFLISAAI 270 thale cress 19114377 161 LFISTAMSITAFPVLARILSELHLLHKRVGVIVLSAGIGNDVIGWILLALSVTLVNSGs--------GvraVYILLLALG 232 fission yeast
25407027 1256 FVVVMICVVRPAMYWVIKQ-TPEGRPVKDFYLYSIFGIAFACFTFFNKVIHLFGPAGSFVFGLTVPNGYPLGTTLIQKFE 1334 thale cress 15219224 216 ATGVIILTNRFLASWLPKR-NPKEKYLSKAETLAFIILILIIALTIESSN-LNSTLFVFIIGLMFPREGKTYRTLIQRLS 293 thale cress 25411916 114 FNLDNENGVEDTPRLIDRKdNVFI--MSNPKSKYPVL-QLDLRLISDLVVVIVS---ATCGGIAFA-------CAGQPVI 180 thale cress 15231125 225 QVTFTSIVSPIFLNWVNNE-NPEGKPLKGFPTWPPESMYNPILS-------------AFTAGLFLPNKGRMSKWIINKIN 290 thale cress 7444648 138 NGLALSSTAVVLQVLQERGeSTSR--HGRATFSVLLFQDLAVVVLLILIPLISPN--SSKGGIGFQ-------AIAEALG 206 thale cress 25407295 218 AALSLSSSAFVLQLLAEKGeLPTR--FGSATLGILLLQDIAVVPLLVILPVLE---SQDIGGESIW---P---MLAK--E 284 thale cress 15241036 251 DNDIGDSICVPTTNAVDEE-S--NTRRTLSQGLLSLCYMR------------------LALHLLP-------------LG 296 thale cress 10177870 116 FSLENED--SDDMTLIDKKnNVFV--MSNKKSKYPIL-QVDLRLISDLVVIIVF---AAIGGIVFS-------CLGQPVI 180 thale cress 15237673 271 MAACLLLVVKRSFEWIVAK-TPEGGLVNQNYIVNILMGVLVSCFLTDMFGMAI-AVGPIWLGLVVPHGPPLGSTLAIRSE 348 thale cress 19114377 233 WCLFLFIAIKPLVYLLAVKtRSLKDKPSESFICIVLSMVLVSAFFTDIIG-IHPIFGGFLVGTIIPHENDLTVKITEKIE 311 fission yeast
25407027 1335 SFN-LGSILPLFGSLTMMQVDLLRLFKesgdlirmegqIYEVISFILLVNTTKFVVTTITAY-AFKMPLRDSFALALVLS 1412 thale cress 15219224 294 YPI-HEFVLPVYFGYIGFRFSVNSLTKr---------hYLVLGMTVALSLLGKLLGVLFACS-FLKIPKQYWLFLSTMLS 362 thale cress 25411916 181 TG----YLLAGSIIGPGGLSFVS---------------EMVQVETVAQFGVIFLLFALGLEFsAAKLRVVRAVAIPGGLL 241 thale cress 15231125 291 YLL-STVFYPIFFFWVG---------------------FIIHMRNFDITDKMAWLSSKVKST------------------ 330 thale cress 7444648 207 LAA-IKAAVAITGIIAGGRLLLRPIYK-----------QIAENRNAEIFSANTLLVILGTSLlTAR---AGLSMALGAFL 271 thale cress 25407295 285 SAK---ALGGLGILSLGGKFFLRRIFE-----------VVAETRSSEAFVALCLLTVAGTSLvTQWLGFSDTLG---AFL 347 thale cress 15241036 297 RICgFTLLLWC-----G---RLRSSHPk---------tSASRHGTVRQNRFAKMIAIALPSL-YYKVPLWHAILVGFIVN 358 thale cress 10177870 181 VG----YLLAGSIIGPGGLKFIS---------------EMVQVETVAQFGVVFLLFALGLEFsMTKLKVVGPVAVLGGLL 241 thale cress 15237673 349 TFV-NEFLMPFSFALVGQKTNVNLISKetw-----pkqISPLIYMSIVGFVTKFVSSTGAAL-FFKVPTRDSLTLGLMMN 421 thale cress 19114377 312 DLV-NCLFLPLYFASSGLKTNISTLNTgk--------iWGYTIGTICVAIASKMGSSMLAAR-ILKMPWSDSLVVGSLMS 381 fission yeast
25407027 1413 NKGIFELAYYTYAVELKLIRPEVFTILAAYTLLNSIFIPMLLELVHDPTKRFRC-----YRKRNLGILK-------DGAA 1480 thale cress 15219224 363 VKGHIGLVLLDSNLMYKKWFTPVVHDMFVAALVIMTLLSGVITSLLLRSQEKSFa----HIKTSLELFD-------TTEE 431 thale cress 25411916 242 QIFLFMCLSGITASLCGGKLTEGIFVGAFLSMSSTAVVLKFLMERN-SISALHG-----QIT--------------DCAV 301 thale cress 15231125 331 ----------------------TGALIIFIIVFTVVYSPFVVMDIIKRARKRVP-----VHIMALQWLD-------PTTE 376 thale cress 7444648 272 AGLLLAETEFSLQVESDIAPYRGLLLGLFFMTVGMSIDPKLLLANFPLIMGTLG-----LLLVG------------KTIL 334 thale cress 25407295 348 AGALLAETNFRTQIEADIRPFRGLLLGLFFVTTGTSIDMEVLFREWPNVLSLLGgl--iVIKTLIITAIgprvgltIQES 425 thale cress 15241036 359 IQGLYDVQIYKQNFNYTKISSKSFGAMVMSATVNSTIFIVIVKKLYQTMSKRNP-----YKRRTVQHCR-------VEAP 426 thale cress 10177870 242 QIVLLMFLCGVTALLCGARLSEGIFVGAFLSMSSTAVVVKFLVERN-STSSLHG-----QVTIGILIFQ-------DCVV 308 thale cress 15237673 422 LRGQIDILLYLHWIDKQMVGLPGYSVMVLYAIVVTGVTAPLISFLYDPTRPYRS-----SKRRTIQHTP-------QNTE 489 thale cress 19114377 382 CKGLVELIVLNIGLSTGILNETIFSMFVFMAVITTFVTTPMTKFFLRFTKSEHDdnsieSSEELVQYLP--------ELP 453 fission yeast
25407027 1481 LQCLMCVYRPDHITSMTDLLETFSPSQDS-----PMACNILHLVEL-VGQANP-MFISHQLQKP---------------- 1537 thale cress 15219224 432 LRVLTCVYGVRHARGSISLVSALSGFSPGts-ssPFTPYLMHLIPL-PKKRKT-ELLYHELDEDagns------------ 496 thale cress 25411916 302 GLLFALLPVLGGTSGVLQGVLSMAKSL-------AILIAFLGALFV-LSRTW----VPWFLKLM---------------- 353 thale cress 15231125 377 LRILIGLHGPHNIGSTLNVMEICHGGREP-----GSIFYATDMVEL-TDEIAAtLKKGGGAGQSnd-------------- 436 thale cress 7444648 335 VVIIGKLFGISIISAVRVGLLLAPGGE-------FAFVAFGEAVNQ-VIIYMM-ISVFCFFTMG---------------- 389 thale cress 25407295 426 VRVGFLLSQGGEFAFVVFSLANRLGVLPN-----ELNKLLIIVVVL-SMALTP--YLNQLGRKAa--------------- 482 thale cress 15241036 427 LRILTCFRNREAVRPVLDLVELSR-PAIGs----PLSVFAVNLEEL-NNHSLP-LLIHHT--QEi--------------- 482 thale cress 10177870 309 GLLFALLPVLGGNSGLLQGIISMGKLL-------LILSIYLTVASL-LTWSF----VPRFLKLM---------------- 360 thale cress 15237673 490 TGLVLAVTDHDTFSGLITFLDFAYPTKTS-----PFSVFAIQLVEL-EGRAQP-LFIAHDKKREeeyee----------- 551 thale cress 19114377 454 TRLSFLINHPLDASAAMIFIQHIYENRDKvsgclHLPQIIIHSIWTlFVDSRTsNLLRASQVDNkvenealmglfetfvk 533 fission yeast
25407027 1538 -----EPGSTSLSD-NV--IISFRGFQR-Qf-------FEYTSLDIFTSVSVSQHMHEDICWLALSRSLSLIVLPFHRTW 1601 thale cress 15219224 497 --nggDDEFGTNEGlEI--NDSIDSFTRdR----------KIMVRQVKLVAPMENMHEEICNATEDLRVSIVFLPFHKHQ 562 thale cress 25411916 354 -----TSLS------SQ--TNEL--YQL-----------AAVAFCLLVAWCSDKLGLSLELG-SFAAGVMISTTDLAQH- 405 thale cress 15231125 437 ---svTVTDRSVTEmREsiTAAVNGYGElRn-------GQGVTVRRMLALSTFVTMAHDVCGLADELMVSIIILPFHKRL 506 thale cress 7444648 390 -----LVTA------VF--LGELDWYFF-----------QGIMTPQLSSLLFLVVGISMALTPWLAAGGQLIASRFELQ- 444 thale cress 25407295 483 ----dFLDERLDPGeKIgeDVNFDVSESiVi------iGFGQMGQVLANFLSTPLVSDSDLVGWPYIGFDLNPAVVKESR 552 thale cress 15241036 483 -----SPFLVPSRRdQI--VKAFHNFEKtN--------QETVLIECFTAVAPRKTMHEDVCAIAFDQETDIVILTLDAGI 547 thale cress 10177870 361 -----IQLS------SQ--TNEL--YQL-----------AAVAFCLLSAWCSDKLGLSLELG-SFVAGVMLSTTEFAQH- 412 thale cress 15237673 552 -eeepAERMGSRRVdQV--QSAFKLYQE-Kr-------SECVTMHAYTAHASKHNMYQNICELALTKKTAFILLPYQKER 620 thale cress 19114377 534 ikkfeYESNALLVSgTGyyNVVLETLKKsSsnilimpyLKDYKTIENESSSSPLSLSSIRLALGDSFKSLDELIPLIKMA 613 fission yeast
25407027 1602 Sv------DRSTVISNDDNLRMLNVNVLRRAPCSVGIFVYR---------------KPIVESHMAK--SHSKICLIFNGG 1658 thale cress 15219224 563 R-------IDGKTTNDGEVFRHMNRKVLKQAQCSIGIFVDRn---------------ITGFHQLHGsdSVQHVAALFFGG 620 thale cress 25411916 406 -----------TLEQARSQVEPIRNFFAALFLASIGMLIH-------------------------------M---HFLWN 440 thale cress 15231125 507 N-------PDGTLDAGHAGFRHVNRKILKNAPCSVGILVDRsf---------------gQTEEAWRpgASMGIAIIFIGG 564 thale cress 7444648 445 -----------DVRSLLPVESETDDLQGHIIICGFGRIGQ---------------------------------VLHKIGA 480 thale cress 25407295 553 K-------LGFPILYGDGSRPSVLQSAGVSSPKAIMIMYKG---------------------KKRTteAVQRLRLAFPGS 604 thale cress 15241036 548 ----------------ELWERLLCRNLLHNCPCSVALFIDRgrl----------pdFR--FVPLKK--LTINIGAIFLGG 597 thale cress 10177870 413 -----------TLEQV-LILNSGRFCFAS---TCIGMLIN-------------------------------V---HFLWN 443 thale cress 15237673 621 Lq------DAALTELRDSGMLSVNADVLAHTPCSVCIYYEKgrlknamvrssmdpqHTTNSSHMRQ--EMYRFVVLFLGG 692 thale cress 19114377 614 RipvgvffTRNPHNLSVKKIRPIIRSTEYGSPKNDFEQLEKdkks--------fdqVEISVKEKGStyERSKVVILIYLG 685 fission yeast
25407027 1659 KDDRE---ALAITNRMRLtEKRTRLTIIRFIPKSSEMDNDEWEQQQSINLKESVTSI-V---GSNIKENDAKVTYi---- 1727 thale cress 15219224 621 PDDRE---ALSLCKWLTN-NSQIHLTVIQFVADDSKTEKIVGDAVTKENNEVFLEIVsE---DQTENETDRIFLEefyhr 693 thale cress 25411916 441 HVDIL---LAAVLLVIVI-KTVVVAIVVKVFG----YNNKTAVLVGMSLAQIGEFAFvL---LSRASNLHLIES------ 503 thale cress 15231125 565 RDDRE---ALAFAAQVAR-HPAVKLKVIRFLEDKSSQNAQKRSSILNRASVVDQEEEmKlddECFAEFYERYIAGggrv- 639 thale cress 7444648 481 DRACA---AAIALDTPGA-NYRCVWALSKYFPNVKTFVRAHDVDHGLNLEKAGATAVvP---ETLEPSLQLAAA------ 547 thale cress 25407295 605 PIYAR---AQDLPHLLELkKAGATDAILENAETSLQLGSKLLTGFGVMSDDVSFLSKvFrdsMEIQAQEEITASEtn--- 678 thale cress 15241036 598 PDDRE---MLAYATRLAS-HPSVELQVFRLVDQNGVSPLR--DMVERNHDMRVINVF-R---KENSEK-NIIFRE----- 661 thale cress 10177870 444 HVDIL---LASVILVIVI-KTAIAAVVVKAFR----YNMRISFHVGVLLAQIGEFAFvL---LSRASNLHVIEG------ 506 thale cress 15237673 693 ADNRE---ALHLADRMTE-NPFINLTVIRFLAHNHEGED----EREKKLDDGVVTWF-W---VKNESNARVSYK------ 754 thale cress 19114377 686 TENDLialELLLKFLYEEtSIAYIYTYDEFYKDDYATSLPNVVYTSEVLLSKHNDSAfKvwpKLRKNIRKITKPNgfttd 765 fission yeast
25407027 1728 ------------DKAVSDGSETSRILRAMAN--DYDLFIVGSGSGIGTE-ATSGISEWTEFNELGP-IGDLLASHEY-PS 1790 thale cress 15219224 694 fvt--tgqvgfiEKRVSNGMQTLTILREIGE--MYSLFVVGKNRG-DCP-MTSGMNDWEECPELGT-VGDFLASSNMdVN 766 thale cress 25411916 504 -------------KLYLLLLGTTALSLVTTP----LLFKLIPAVVHL-----GVLLRWFSPDSSTE-IGFKGELYHSeSA 560 thale cress 15231125 640 ---------symEKHLTNSSETFTALKSLDG--EYGLVIVGRGGGRASSgLTTGLNDWQQCPELGP-IGDVLSGSDFsHN 707 thale cress 7444648 548 -------------VLAQAKLPTSEIATTINE----FRSRHLSELAELCE-ASGSSLGYGFSRSTSK-PKPP---SPSeTS 605 thale cress 25407295 679 ----------agLKPMQMKASDINVVSAATQ----KQVQLMKPMQMKAS-DSNSDSAAEILQETAG-LSQPPEIDDSsVN 742 thale cress 15241036 662 -------------VRIEEAVNLLDLLRKEGD--DFDLMMVGIRHEENLL-MLEGLSEWSDMKELGE-VGDVLISKDL-EL 723 thale cress 10177870 507 -------------KMYLLLLGTTALSLVTTP----LLFKLIPSAMNL-----GVLLRWF-PSENS-------------SP 550 thale cress 15237673 755 ------------EVVVKNGAETLAAIQAMNVn-DYDLWITGRREGINPK-ILEGLSTWSEDHQLGV-IGDTVAGSVF-AS 818 thale cress 19114377 766 qhsqtfipsqthTKLDLRLSDVTDSVRSRINvvKFGNLNSLLSCLHELIqPATLTPSFETEKSITMfLGCRDKQAVSeKL 845 fission yeast
25407027 1791 KILWDLCETIRPV--L 1804 thale cress 15219224 767 ASVLVVQRHRNSFd-S 781 thale cress 25411916 561 KRISLMIQGSLHDs-- 574 thale cress 15231125 708 TSMLIIQQQRTRG--Q 721 thale cress 7444648 606 DDNQIIEG-TLAI--- 617 thale cress 25407295 743 IDNGFVGKADKAQd-- 756 thale cress 15241036 724 SVSVLAVQQ------- 732 thale cress 10177870 551 NEVILFSR-SIYI--- 562 thale cress 15237673 819 EGSVLVVQQQVRN--Q 832 thale cress 19114377 846 EVAALSEMKKLGYieS 861 fission yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",