Conserved Protein Domain Family
Troponin
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pfam00992: Troponin (this model, PSSM-Id:366404 is obsolete and has been replaced by 460018)
Troponin
Troponin (Tn) contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). this Pfam contains members of the TnT subunit. Troponin is a complex of three proteins, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). The troponin complex regulates Ca++ induced muscle contraction. This family includes troponin T and troponin I. Troponin I binds to actin and troponin T binds to tropomyosin.
Links
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Statistics
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PSSM-Id: 366404
Aligned: 104 rows
Threshold Bit Score: 48.6925
Created: 23-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q0D2W2        11 RHHLKSLVLSIAFNLLDAEAKQHIADKESHMSENCPALD-LPGsvQELQDLCKKLHQQIDKVDEERYDMEAKVAKADKEI 89  zebrafish
CBY22310       7 qRAEKDLAELKKLIENHFAQRKQDEEVLNELVQKMESRKeLRQ--RQIEDRNQREKERAQRERDDRNKREETEAKKKLEE 84  Oikopleura dioica
CAG02062      71 KRMEKDLLELQTLIDVHFDQRKKDEEELISLKERIERRRaERA--EIQRVRAEKEKDRQNRIAEERHRKEEEEAKKKADD 148 spotted green p...
PWA21945      81 KRMEKDLLELQTLIDVHFEQRKKEEEELIGLKDRIERRRaERA--EQQRVRAEKERDRQTRIAEERQRKEDEEAKKRADD 158 western mosquit...
XP_012019000  60 KRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRaERA--EQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAED 137 mouflon
XP_011474243  48 KRQEKDLAELQSLIEAHFVQRHKDEEELVALVNRIDKRRaERA--EQQRVRAEREKERQARLADERERREQEEQRKKQDD 125 Japanese medaka
XP_007252908  48 KRQEKDQSELQALIEAHFIQRKKEEEELIALVNRIEKRRtERA--DQHRIRAEKEKERQARLAEEKERKEQEEQRKKQDE 125 Mexican tetra
XP_013126051  50 KRQEKDLAELQSLIEAHFVQRKKEEEELVALVNRIEKRRsERA--EQQRIRAEREKERQNRLAEEKERKEQEEQRKKMDE 127 Nile tilapia
XP_015194440  82 KRMEKDLMELQTLIESHFIQRKKEEEELIALVNRIEKRRtERA--EQQRIRTEKEKERQAKLAEEKARKEEEEHRKKHVD 159 spotted gar
XP_004225995  46 KRMEKDMVELQGLINAHFEQRKKDEEEIEELRVRIEERKsKRA--EQIRIRQDRERERMAQEREERKRKEEEEESKRQEE 123 vase tunicate

Q0D2W2        90 EDLKIKVIDLKgK-FKKPALK-------KVRMSADAMLQALLGSKHK-VSMDLRANLKQVK 141 zebrafish
CBY22310      85 EEKKKDALAAMsMnYGGYLAKrqeqarnKRGGAEKEKKKKILADRRKpLNIDHMDNDKLQA 145 Oikopleura dioica
CAG02062     149 EAKKKKVLSGMgAnFGGFLAKaet--rkGKRFTGREIKKKTLAERRQpLAIDSLREDGLRQ 207 spotted green pufferfish
PWA21945     159 EAKKKKVLSNMgAhFGGFLAKeeq--rrGKRQTAREIKKKTLAERRKpLSIESLKEDGLR- 216 western mosquitofish
XP_012019000 138 DAKKKKVLSNMgAhFGGYLVKaeq--krGKRQTGREMKVRILSERKKpLNIDHMGEEQLRE 196 mouflon
XP_011474243 126 DAKKKKVLTNMtQqYTVGQKnen--rkgAKKQTEREKKKKALAERRKpLNIDHLNEDKLKE 184 Japanese medaka
XP_007252908 126 DAKKKKALTNMtHqYGGLQQRtdg-rkgGKKQTEREKKKKILADRRKpLTIDHLNEDKLRE 185 Mexican tetra
XP_013126051 128 DAKKKKALSNMsQqYGA-GQKsdt--rrGKKQTEREKKKKILAERKKpLSVDHLNEDKLKD 185 Nile tilapia
XP_015194440 160 DAKKKKALSNMsFqYGSYLQKtes-rrgAKKQTEREKKKKILAERRKaLNIDHLNEDKLKy 219 spotted gar
XP_004225995 124 EARKKAAIANMsLhYGGYLARaek-nkpNKRQTDREKKKKLLADRRKpLNIDHLSDDKLKE 183 vase tunicate
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