2494301 11 SPIHPAIis-----------rQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKCSNeecp 79 fission yeast 3122252 2 RRNPSTFkyiplridfmsevpLPEVNIGLVGHVDHGKTTLVAALSGVWTDRHSEELKRGISIKLGYADATFRKCPE---- 77 Archaeoglobus fulgidus 7674079 8 SGGDKR---------------QPEVNIGVVGHVDHGKTTLVQALTGVWTMRHSEEIRRGMTIKLGYADGEVWECEG---- 68 Aeropyrum pernix 20092490 23 ISDYLHStggn------ynlsQPCVNIGMVGHVDHGKTTLVKALSGVWTDTHSEEVKRGISIRLGYADSPFMKCPK---- 92 Methanosarcina acet... 20094883 1 MDDERf--------------qQAEMNIGMVGHVDHGKTTLTKALSGVWTDTHSEETRRGISIRLGYADTVLTRCPE---- 62 Methanopyrus kandle... 18311686 1 MAFVY-----------------PDAIVSTAGHVDHGKTQTTYALSGVWVMRHSEEIKKAMTIKLGYTQIGIYDCGE---- 59 Pyrobaculum aerophilum 15897345 1 MAWPKV---------------QPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCES---- 61 Sulfolobus solfatar... 13542105 2 ISKLKMP--------------QPTVNIGMVGHVDHGKSTLTLALTGVKTDTHSEEIKRGISIKLGYADTPVYKCYD---- 63 Thermoplasma volcanium 13878555 2 ISKLKMP--------------QPSVNIGMVGHVDHGKSTLTLALTGTKTDTHSEEIKRGISIKLGYADTPIYRCYD---- 63 Thermoplasma acidop... 20532138 1 MAD-EHR--------------QPEVNIGLVGHVDHGKTTLVRALSGEWTDQHSEEMKRGISIRLGYADATLRRCPD---- 61 Halobacterium sp. N...
2494301 80 rpgCYRSysSNKEDHPPCEICNSPm--NLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAI 157 fission yeast 3122252 78 ---CEPP--EAYTVEEICPIHGVEt--EILRTVSFVDSPGHEMLMATMLSGAAIMDGAVLVIAANEKCPRPQTKEHLMAL 150 Archaeoglobus fulgidus 7674079 69 ---CGFP--ERFSPEPVCE-CDPQasaSLRRRVSYVDAPGHEILMATMLSGAALMDGALLVVAANEPCPQPQTKEHLVAL 142 Aeropyrum pernix 20092490 93 ---CPAP--QCYTVEKTCPNCGEKt--EEHRIVSFVDAPGHETLMATMLSGAAIMDGAVLVIAANEECPQPQTKEHLMAL 165 Methanosarcina acet... 20094883 63 ---CD-----TYSVEEKCPECGAEt--EWLRRVSFVDSPGHETLMATMLSGAAIMDAAILVIAANEPCPQPQTREHLMAL 132 Methanopyrus kandle... 18311686 60 ---EYYYs-DGILQNGKCP-NGAEp--KLIRRISLLDVPGHEVLVATMVSGAAVVDGALLVVDASQPAPQPQTVEHFAVL 132 Pyrobaculum aerophilum 15897345 62 ---CKKP--EAYVTEPSCKSCGSDdepKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVAL 136 Sulfolobus solfatar... 13542105 64 ---ASG---NPYYTRQPSENC------ELERVISIVDAPGHETLMATMLSGSALMNGALLVIAANEHCPQPQTREHLTAL 131 Thermoplasma volcanium 13878555 64 ---SSG---NVHYTREKGENC------DLERVISIVDAPGHETLMATMLSGSALMNGALLVIAANEHCPQPQTREHLTAL 131 Thermoplasma acidop... 20532138 62 ---CDEP--ECYTVAETCPEHDTAt--EIERTVSFVDAPGHETLMATMLSGAALMDGAVLVVGANEPVPQPQTEEHLMAL 134 Halobacterium sp. N...
2494301 158 EIMQLKHIIILQNKVDLIRESAAEEHYQSILKFIKGTV---AENSPIVPISAQLKYNIDAILEYIVKKIPIPVRDFTTAP 234 fission yeast 3122252 151 QIIGIDKIVIAQNKIDIVSRERVLENYQEIKEFVKGTV---AENAPIIPISAQQKVNMDALIEAIEETIPTPERDLDSPP 227 Archaeoglobus fulgidus 7674079 143 EIIGIKNIVIVQNKVDVVSRERAKESYQEILNFIKGTI---AEGSPIIPVSALKRANIDAVLAAIEKFIPTPPRDLDKPP 219 Aeropyrum pernix 20092490 166 DIIGIKNIVIVQNKIDLVSREKLVENYHQIKEFVKGTV---AENAPIIPISAQQNINIDVLIDALETQIPTPVHKVDKPA 242 Methanosarcina acet... 20094883 133 EIIGTEDVIVVQNKIDLVTPEEAREHYEQIVQFLEEEThldPDKTPIIPVSAQHKANLDVLVEAMYEHFEPPEYDLDAPF 212 Methanopyrus kandle... 18311686 133 DIIGVRHMVVAQNKIDLVTKEKALENYEQIKNFLKGTW---AEKAKVVPISALHRVNIDALVTYLAKEIPKREAELGKPA 209 Pyrobaculum aerophilum 15897345 137 GIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTW---AENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKP 213 Sulfolobus solfatar... 13542105 132 EIMGIKNIVIVQNKIDLVTRERALESYKEIKAFVKGSI---AENAPIIPVSAYHNTNIDILFEAIEKYIPTPEYNEGSDP 208 Thermoplasma volcanium 13878555 132 EIMGIKNIIIVQNKIDLVTRERAIESYREIKNFVKGSI---AENAPIIPVSAYHSTNIDALFEAIEKYIPSPKFNENDDP 208 Thermoplasma acidop... 20532138 135 DIIGIENIVIAQNKVDLVDAEEARQNYEEIQAFVEGTV---AEDAPVVPVSAEQEINVDLVIDALQTEIATPDRDPSADP 211 Halobacterium sp. N...
2494301 235 RLIVIRSFDVNKPGAEVDDLKGGVAGGSILTGVLRLNDEIEIRPGIVTKDDDgRIRCQPIFSRIISLFAEHNDLKIAVPG 314 fission yeast 3122252 228 LMHVARSFDVNKPGTPPEKLLGGVLGGSLSRGRIRVGDEIEIRPGV---KDE-RGNWNPLFTEVQSIVASGRFVDEATPG 303 Archaeoglobus fulgidus 7674079 220 VMYISRSFDVNRPGTPPERLVGGVVGGSIIQGVFRVGDEIEISPGVAVRKPGgRVEYVRLHTTITSLRFGSIEVEEARPG 299 Aeropyrum pernix 20092490 243 SMLIARSFDINKPGASIDEIRGGVIGGTLTEGVLHPGDELEIRPGIKVTTEG-STKWIPIVTTISSIYAGPTKVEEATPG 321 Methanosarcina acet... 20094883 213 RMYIARSFDVNKPGTRPSDLKGGVIGGAIVQGEVEIGDEIEIRPGIRVERYG-RTEWEPVYTEVVSLHANVTPVERARPG 291 Methanopyrus kandle... 18311686 210 LFSVLRSFNVNPPGTAPDKLRGGVLGGTLLRGVLRVGDEIELRPGLKVDKPK--PGYQPIYTKVLSIEYSGQKVEEARPG 287 Pyrobaculum aerophilum 15897345 214 VMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQG-KVSYEPIFTKISSIRFGDEEFKEAKPG 292 Sulfolobus solfatar... 13542105 209 IMYIARSFDVNKPGTPIDQIKGGIIGGSLTQGSLKIGDEIEIVPGIQNTRGN-KTVWTNVTTEVVSLMAGKYSYDMIKPG 287 Thermoplasma volcanium 13878555 209 IMYIARSFDINRPGTPVSELKGGVIGGSLTQGEFALGDEIEIVPGIQTTKGN-KTVWNNVTTEVVSLMAGKYSYDRIRPG 287 Thermoplasma acidop... 20532138 212 LLYAARSFDINRPGTEWGGLLGGVIGGSLVDGELEAGDELELRPGREVEEGG-KTEWRPVTTDVRSLQAGGEDVDSASPG 290 Halobacterium sp. N...
2494301 315 GLIGVGTTVDPTLCRADRLVGQVLGSKGNLPEVYTELEINYFLLRRLLGVKsgdkNTTKVQKLAKNEVLMVNIGSTSTGG 394 fission yeast 3122252 304 GLVGIATKLDPTLTKSDALVGNVVGHPGNLPDVLTSFTMEVNLLERVVGLD----EEMEVEKIKMNEPLMLAVGTAITLG 379 Archaeoglobus fulgidus 7674079 300 GLVAIGTQLDPSVTKADNLVGNVVGKPGELPEPLTTLRIEHHLLEKVVGMK----EEARVEPIRRGEMLMLSVGTAITLG 375 Aeropyrum pernix 20092490 322 GLLAVGTYLDPTLTKGDSLTGQIAGVPGTLPETRHQFVMELHLLDRVVGVT----REEKINEIKTSEPLMLNIGTATTVG 397 Methanosarcina acet... 20094883 292 GLVGIGTKLDPTMTKADRLSGQVAGEPDTLPPVRHELLLEVELLERVVGTE----EERKVEPIRTNEVLMLTVGTATTVG 367 Methanopyrus kandle... 18311686 288 GLVGIMTGLDPALTKADALAGAVVGKPGTLPPVWTAVEVETRPIPRALA--------EKIEPFKQNEVVLLAVGPATVFG 359 Pyrobaculum aerophilum 15897345 293 GLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAK----EMLKVDPIRAKETLMLSVGSSTTLG 368 Sulfolobus solfatar... 13542105 288 GLAAVGTKLDPFLTKGDAFTGRIAGYIGKVPPISFSMRLEAHLLKRVVGSD----QELNVEPIRAKETLMFTVATANTVG 363 Thermoplasma volcanium 13878555 288 GLAAIGTKLDPFLTKGDAFTGRIAGHVGKVPPVAFSMRLESHLLKRVVGSD----QELNVEPIRPKETLMFTVATANTVG 363 Thermoplasma acidop... 20532138 291 GLLGVGTGLDPSLTKGDALAGQVAGPPGSLPPTWESFEMDVDLLERLVGAA----DGEQIDDISTGEPLMLTVGTATTVG 366 Halobacterium sp. N...
2494301 395 RVMMVKADMAKILLTAPACTEI-GEKVALSRRIEKHWRLIGWAKVVEGK 442 fission yeast 3122252 380 VVTSARDDIVEVKLRRPVCADK-GSRVAISRRVGSRWRLIGAGIIR--- 424 Archaeoglobus fulgidus 7674079 376 VVTRAGKDEIEVQLRRPVVTWP-KARVALSRRIMGRWRLIGWGLIK--- 420 Aeropyrum pernix 20092490 398 IVTSARKNEAQVALKRPISAAV-GAMVAISRRIDSRWRLIGVGVIKS-- 443 Methanosarcina acetivorans C2A 20094883 368 VVTSARDDEIEIKLKQPVCAEE-GDRVAISRRI-QRWRLIGHGVIKG-- 412 Methanopyrus kandleri AV19 18311686 360 VVQAVKKDAITVALKKAVCAEQ-GSKVVVIRQVKNRWIVTNYGTLKGGT 407 Pyrobaculum aerophilum 15897345 369 IVTSVKKDEIEVELRRPVAVWSnNIRTVISRQIAGRWRMIGWGLVEI-- 415 Sulfolobus solfataricus 13542105 364 VVSNVKGTDIEVSLKYPVAAFN-GMRVAIGRRVLNRWRLIGYGVIESLE 411 Thermoplasma volcanium 13878555 364 VVNAMKGSEIEVSLKYPVAAFN-GMRVAIGRRVMNRWRLIGYGIIQSLE 411 Thermoplasma acidophilum 20532138 367 SVTSARDGECEVALKRPVCAPA-GAKIAINRRVGARWRLIGVGTLTESE 414 Halobacterium sp. NRC-1
Jiyao W et al.(2023). "The conserved domain database in 2023.",